Incidental Mutation 'R1921:Atrn'
| ID |
213027 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| MMRRC Submission |
039939-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1921 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
130748415-130872253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 130836971 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 1145
(Y1145C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000028781
AA Change: Y1145C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: Y1145C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132557
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134964
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151364
|
| Meta Mutation Damage Score |
0.9433 |
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.7%
- 10x: 94.9%
- 20x: 91.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
C |
A |
6: 121,631,571 (GRCm39) |
L623M |
probably benign |
Het |
| Abhd2 |
T |
C |
7: 78,998,104 (GRCm39) |
I212T |
possibly damaging |
Het |
| Adam7 |
A |
C |
14: 68,750,074 (GRCm39) |
S449A |
possibly damaging |
Het |
| Alkbh2 |
C |
T |
5: 114,262,287 (GRCm39) |
E148K |
probably damaging |
Het |
| Aox3 |
T |
C |
1: 58,219,810 (GRCm39) |
Y1137H |
probably damaging |
Het |
| Atp11b |
T |
C |
3: 35,888,474 (GRCm39) |
Y715H |
probably damaging |
Het |
| Btbd7 |
A |
G |
12: 102,760,055 (GRCm39) |
I631T |
probably benign |
Het |
| Cadps |
T |
C |
14: 12,465,859 (GRCm38) |
K1017R |
possibly damaging |
Het |
| Cfap45 |
A |
G |
1: 172,372,679 (GRCm39) |
E458G |
probably damaging |
Het |
| Cptp |
C |
T |
4: 155,950,995 (GRCm39) |
R157H |
probably damaging |
Het |
| Dcbld1 |
A |
C |
10: 52,195,747 (GRCm39) |
E318D |
possibly damaging |
Het |
| Ddr2 |
G |
T |
1: 169,831,814 (GRCm39) |
P197Q |
probably damaging |
Het |
| Dlg5 |
T |
C |
14: 24,226,639 (GRCm39) |
Y421C |
probably damaging |
Het |
| Dlgap2 |
A |
G |
8: 14,893,624 (GRCm39) |
K980E |
probably benign |
Het |
| Drc7 |
T |
C |
8: 95,782,644 (GRCm39) |
V3A |
unknown |
Het |
| Dst |
T |
C |
1: 34,200,110 (GRCm39) |
V96A |
probably damaging |
Het |
| Ect2l |
T |
C |
10: 18,018,752 (GRCm39) |
D548G |
possibly damaging |
Het |
| Efcab10 |
A |
T |
12: 33,448,434 (GRCm39) |
Y89F |
probably benign |
Het |
| Eif1ad |
CGAGGAGGAGGAGGAGGAGG |
CGAGGAGGAGGAGGAGG |
19: 5,420,086 (GRCm39) |
|
probably benign |
Het |
| Entpd6 |
A |
G |
2: 150,600,732 (GRCm39) |
T147A |
probably damaging |
Het |
| Fbxl5 |
T |
A |
5: 43,922,832 (GRCm39) |
E189D |
probably benign |
Het |
| Fer1l6 |
T |
A |
15: 58,497,080 (GRCm39) |
S1217T |
probably damaging |
Het |
| Frem2 |
A |
T |
3: 53,560,916 (GRCm39) |
V1197D |
possibly damaging |
Het |
| Fsip2 |
T |
A |
2: 82,811,127 (GRCm39) |
L2482* |
probably null |
Het |
| Fsip2 |
A |
T |
2: 82,817,164 (GRCm39) |
D4299V |
probably benign |
Het |
| Gipc3 |
T |
A |
10: 81,174,049 (GRCm39) |
I242F |
probably damaging |
Het |
| Hoxb1 |
T |
A |
11: 96,256,938 (GRCm39) |
Y96N |
probably damaging |
Het |
| Ibsp |
A |
G |
5: 104,458,078 (GRCm39) |
E205G |
probably damaging |
Het |
| Ibtk |
A |
G |
9: 85,585,135 (GRCm39) |
S1170P |
probably benign |
Het |
| Igfn1 |
A |
G |
1: 135,893,801 (GRCm39) |
|
probably null |
Het |
| Iqsec1 |
A |
G |
6: 90,639,877 (GRCm39) |
S954P |
probably benign |
Het |
| Kalrn |
A |
T |
16: 34,212,463 (GRCm39) |
D28E |
probably benign |
Het |
| Lrmda |
T |
C |
14: 22,627,938 (GRCm39) |
F52L |
probably damaging |
Het |
| Lrp2 |
T |
C |
2: 69,353,631 (GRCm39) |
D543G |
probably damaging |
Het |
| Lrrtm3 |
T |
C |
10: 63,924,157 (GRCm39) |
T337A |
probably benign |
Het |
| Marf1 |
C |
T |
16: 13,946,465 (GRCm39) |
D1219N |
possibly damaging |
Het |
| Mkln1 |
A |
G |
6: 31,405,113 (GRCm39) |
K118R |
probably benign |
Het |
| Nedd4l |
T |
C |
18: 65,300,646 (GRCm39) |
|
probably null |
Het |
| Neu2 |
A |
G |
1: 87,525,023 (GRCm39) |
E336G |
probably benign |
Het |
| Nfasc |
A |
G |
1: 132,538,543 (GRCm39) |
F448S |
probably damaging |
Het |
| Nlrx1 |
C |
A |
9: 44,165,431 (GRCm39) |
E822* |
probably null |
Het |
| Nr5a1 |
T |
C |
2: 38,584,108 (GRCm39) |
Y437C |
probably damaging |
Het |
| Or4c119 |
A |
G |
2: 88,986,925 (GRCm39) |
V198A |
probably benign |
Het |
| Or7a37 |
T |
A |
10: 78,805,975 (GRCm39) |
L164* |
probably null |
Het |
| Or8b38 |
T |
C |
9: 37,972,981 (GRCm39) |
Y122H |
probably damaging |
Het |
| Phtf1 |
C |
T |
3: 103,876,438 (GRCm39) |
Q13* |
probably null |
Het |
| Pnldc1 |
A |
G |
17: 13,107,815 (GRCm39) |
L525P |
possibly damaging |
Het |
| Ppl |
T |
A |
16: 4,923,988 (GRCm39) |
D162V |
possibly damaging |
Het |
| Prkdc |
T |
A |
16: 15,532,079 (GRCm39) |
S1448T |
possibly damaging |
Het |
| Ptgdr |
A |
G |
14: 45,090,738 (GRCm39) |
I340T |
probably benign |
Het |
| Recql |
T |
C |
6: 142,311,315 (GRCm39) |
I458M |
probably benign |
Het |
| Rrbp1 |
A |
T |
2: 143,830,211 (GRCm39) |
V652E |
probably benign |
Het |
| Rtp1 |
T |
A |
16: 23,250,160 (GRCm39) |
I175N |
probably damaging |
Het |
| Ryr1 |
A |
G |
7: 28,754,369 (GRCm39) |
M3523T |
probably damaging |
Het |
| S100a16 |
T |
C |
3: 90,449,703 (GRCm39) |
L62P |
probably damaging |
Het |
| Samd11 |
T |
C |
4: 156,333,166 (GRCm39) |
E364G |
probably damaging |
Het |
| Satb1 |
C |
A |
17: 52,049,143 (GRCm39) |
G603* |
probably null |
Het |
| Shroom3 |
T |
A |
5: 93,110,224 (GRCm39) |
|
probably null |
Het |
| Slc25a15 |
A |
G |
8: 22,885,777 (GRCm39) |
S3P |
probably benign |
Het |
| Socs2 |
A |
T |
10: 95,248,900 (GRCm39) |
L71* |
probably null |
Het |
| Sptbn1 |
T |
C |
11: 30,054,469 (GRCm39) |
E2208G |
probably damaging |
Het |
| St14 |
A |
G |
9: 31,001,166 (GRCm39) |
V855A |
possibly damaging |
Het |
| Susd1 |
T |
A |
4: 59,412,191 (GRCm39) |
T121S |
probably benign |
Het |
| Svs3b |
A |
T |
2: 164,097,848 (GRCm39) |
S158T |
probably benign |
Het |
| Synpo |
C |
T |
18: 60,736,661 (GRCm39) |
M428I |
probably benign |
Het |
| Syt10 |
C |
T |
15: 89,674,979 (GRCm39) |
D456N |
probably damaging |
Het |
| Taar4 |
A |
G |
10: 23,837,239 (GRCm39) |
D283G |
probably damaging |
Het |
| Tango6 |
T |
A |
8: 107,415,426 (GRCm39) |
D82E |
probably benign |
Het |
| Tcof1 |
T |
C |
18: 60,971,927 (GRCm39) |
T127A |
possibly damaging |
Het |
| Tle3 |
G |
A |
9: 61,318,622 (GRCm39) |
|
probably null |
Het |
| Tmem45a |
A |
G |
16: 56,642,665 (GRCm39) |
F169L |
probably benign |
Het |
| Trp53rkb |
T |
A |
2: 166,637,743 (GRCm39) |
V233E |
probably damaging |
Het |
| Ttc7b |
C |
T |
12: 100,381,389 (GRCm39) |
|
probably null |
Het |
| Tubgcp3 |
A |
T |
8: 12,671,932 (GRCm39) |
L770* |
probably null |
Het |
| Tut1 |
G |
A |
19: 8,943,466 (GRCm39) |
G851D |
probably benign |
Het |
| Ubr1 |
G |
A |
2: 120,761,449 (GRCm39) |
T576I |
probably benign |
Het |
| Vmn1r125 |
T |
A |
7: 21,006,530 (GRCm39) |
Y143N |
probably damaging |
Het |
| Vmn2r120 |
T |
A |
17: 57,831,839 (GRCm39) |
I317F |
probably benign |
Het |
| Vmn2r95 |
T |
A |
17: 18,644,575 (GRCm39) |
N70K |
probably benign |
Het |
| Vps35l |
A |
G |
7: 118,432,971 (GRCm39) |
N568S |
probably damaging |
Het |
| Wdr59 |
A |
T |
8: 112,213,582 (GRCm39) |
L311* |
probably null |
Het |
| Wnt2 |
A |
G |
6: 18,030,252 (GRCm39) |
L12P |
unknown |
Het |
| Xrn1 |
T |
C |
9: 95,881,550 (GRCm39) |
I700T |
probably benign |
Het |
| Ypel1 |
A |
G |
16: 16,900,443 (GRCm39) |
H98R |
probably benign |
Het |
| Zfp219 |
T |
C |
14: 52,245,691 (GRCm39) |
T434A |
probably benign |
Het |
| Zik1 |
A |
C |
7: 10,223,943 (GRCm39) |
C385G |
probably damaging |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,799,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,836,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,789,556 (GRCm39) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
130,844,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,777,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,800,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
130,844,674 (GRCm39) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
130,862,897 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,814,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,789,654 (GRCm39) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,812,064 (GRCm39) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,799,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0403:Atrn
|
UTSW |
2 |
130,748,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,841,085 (GRCm39) |
nonsense |
probably null |
|
|
R0544:Atrn
|
UTSW |
2 |
130,828,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0570:Atrn
|
UTSW |
2 |
130,822,054 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0606:Atrn
|
UTSW |
2 |
130,748,776 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0617:Atrn
|
UTSW |
2 |
130,837,005 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,841,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
130,862,927 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,799,000 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,777,544 (GRCm39) |
missense |
probably benign |
|
|
R1795:Atrn
|
UTSW |
2 |
130,814,208 (GRCm39) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,824,692 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,799,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,812,142 (GRCm39) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,777,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,799,916 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,799,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,803,595 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
130,862,876 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,836,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,806,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,836,148 (GRCm39) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,775,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,812,128 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,802,388 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,815,424 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,823,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,775,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
130,862,910 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,836,967 (GRCm39) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,817,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,836,113 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,812,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R5256:Atrn
|
UTSW |
2 |
130,787,939 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5494:Atrn
|
UTSW |
2 |
130,864,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,811,936 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,748,464 (GRCm39) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,775,356 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
130,862,900 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,788,011 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,821,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
130,864,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,828,664 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,789,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,803,491 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,822,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,806,807 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,812,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,777,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
130,855,561 (GRCm39) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,817,908 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,802,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
130,864,920 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,777,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,846,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,748,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8831:Atrn
|
UTSW |
2 |
130,748,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8937:Atrn
|
UTSW |
2 |
130,841,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,777,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,803,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,786,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF009:Atrn
|
UTSW |
2 |
130,748,842 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0024:Atrn
|
UTSW |
2 |
130,800,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,815,319 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,788,113 (GRCm39) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,787,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGGTGTAAATTACTGAGCAG -3'
(R):5'- GCTAACTGCTCTGGATGACC -3'
Sequencing Primer
(F):5'- GCAGTTAGCAGAAACATTCCTG -3'
(R):5'- CCCCCAAGCATTTATCATT -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation