Mutagenetix > Incidental Mutation

Incidental Mutation 'R1925:Dnhd1'

213351

Institutional Source

Beutler Lab

Gene Symbol

Dnhd1

Ensembl Gene

ENSMUSG00000030882

Gene Name

dynein heavy chain domain 1

Synonyms

8030491N06Rik

MMRRC Submission

039943-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.089) question?

Stock #

R1925 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

105300034-105371006 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 105301459 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Glutamic Acid at position 272 (V272E)

Ref Sequence

ENSEMBL: ENSMUSP00000121261 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000106785] [ENSMUST00000106786] [ENSMUST00000142363] [ENSMUST00000142874] [ENSMUST00000145988] [ENSMUST00000149819] [ENSMUST00000210312] [ENSMUST00000211054]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000106785

SMART Domains

Protein: ENSMUSP00000102397
Gene: ENSMUSG00000110234

Domain	Start	End	E-Value	Type
Pfam:zf-Tim10_DDP	2	67	3.8e-20	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000106786

SMART Domains

Protein: ENSMUSP00000102398
Gene: ENSMUSG00000110234

Domain	Start	End	E-Value	Type
Pfam:zf-Tim10_DDP	3	66	3.6e-18	PFAM
low complexity region	89	107	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000142363

Predicted Effect

probably benign
Transcript: ENSMUST00000142874

Predicted Effect

probably damaging
Transcript: ENSMUST00000145988
AA Change: V272E

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000121261
Gene: ENSMUSG00000030882
AA Change: V272E

Domain	Start	End	E-Value	Type
low complexity region	5	18	N/A	INTRINSIC
low complexity region	102	115	N/A	INTRINSIC
low complexity region	183	191	N/A	INTRINSIC
low complexity region	253	269	N/A	INTRINSIC
low complexity region	943	962	N/A	INTRINSIC
Pfam:DHC_N2	1018	1472	4.6e-50	PFAM
Pfam:AAA_6	1652	1875	2.7e-14	PFAM
low complexity region	1906	1918	N/A	INTRINSIC
Blast:AAA	1993	2196	1e-34	BLAST
Pfam:AAA_7	2362	2610	3.3e-11	PFAM
low complexity region	2697	2714	N/A	INTRINSIC
low complexity region	2722	2733	N/A	INTRINSIC
low complexity region	2800	2810	N/A	INTRINSIC
low complexity region	3116	3134	N/A	INTRINSIC
Pfam:MT	3178	3470	3.9e-16	PFAM
coiled coil region	3590	3642	N/A	INTRINSIC
coiled coil region	3816	3843	N/A	INTRINSIC
Pfam:Dynein_heavy	3976	4746	7.3e-97	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000149819

Predicted Effect

probably benign
Transcript: ENSMUST00000210312

Predicted Effect

probably benign
Transcript: ENSMUST00000211054

Predicted Effect

probably benign
Transcript: ENSMUST00000210893

Meta Mutation Damage Score

0.1932

Coding Region Coverage

1x: 97.5%
3x: 97.0%
10x: 95.6%
20x: 93.2%

Validation Efficiency

99% (79/80)

Allele List at MGI

All alleles(1) : Gene trapped(1)

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc9	T	C	6: 142,617,333 (GRCm39)	H577R	probably damaging	Het
Acvr1	T	C	2: 58,337,661 (GRCm39)	M474V	probably damaging	Het
Adam1a	A	T	5: 121,657,513 (GRCm39)	C593*	probably null	Het
Agap2	A	G	10: 126,926,744 (GRCm39)	N927S	probably damaging	Het
Ahctf1	T	C	1: 179,598,218 (GRCm39)	H958R	probably damaging	Het
Apaf1	A	G	10: 90,835,581 (GRCm39)	V1088A	probably damaging	Het
Brpf1	G	T	6: 113,296,891 (GRCm39)	K958N	probably damaging	Het
Cadps	A	G	14: 12,705,726 (GRCm38)	I223T	probably damaging	Het
Catsperg2	T	C	7: 29,397,189 (GRCm39)	M1105V	probably benign	Het
Clasp2	T	A	9: 113,735,265 (GRCm39)	F1033L	possibly damaging	Het
Col4a3	T	A	1: 82,678,094 (GRCm39)	I1232N	unknown	Het
Col4a3	T	G	1: 82,689,595 (GRCm39)		probably benign	Het
Comtd1	T	G	14: 21,897,731 (GRCm39)	E134A	probably damaging	Het
Cyp2c55	A	T	19: 39,022,821 (GRCm39)	T320S	probably benign	Het
Dlx2	T	C	2: 71,376,522 (GRCm39)	N72S	probably benign	Het
Dpysl3	T	A	18: 43,465,996 (GRCm39)	I140F	probably damaging	Het
Elmod2	G	A	8: 84,048,093 (GRCm39)	A123V	probably benign	Het
Etv4	T	C	11: 101,662,507 (GRCm39)		probably benign	Het
F3	A	T	3: 121,523,032 (GRCm39)	T81S	probably damaging	Het
Faf2	C	T	13: 54,799,865 (GRCm39)	A224V	probably damaging	Het
Fbn1	A	T	2: 125,205,549 (GRCm39)	M1109K	probably damaging	Het
Fnbp4	A	G	2: 90,596,187 (GRCm39)	E586G	probably damaging	Het
Gm10428	G	T	11: 62,644,179 (GRCm39)		probably benign	Het
Gm5884	A	T	6: 128,622,050 (GRCm39)		noncoding transcript	Het
Gm6471	T	A	7: 142,385,319 (GRCm39)		noncoding transcript	Het
Gtse1	T	C	15: 85,757,939 (GRCm39)	V515A	probably benign	Het
H2-M2	T	C	17: 37,793,391 (GRCm39)	E205G	probably damaging	Het
Ido1	T	A	8: 25,075,306 (GRCm39)	T259S	possibly damaging	Het
Il1r2	A	G	1: 40,154,308 (GRCm39)	Y225C	probably damaging	Het
Kcnq3	T	G	15: 65,876,658 (GRCm39)	D495A	possibly damaging	Het
Lrrc49	T	C	9: 60,556,773 (GRCm39)	N321D	probably benign	Het
Lztr1	G	T	16: 17,341,247 (GRCm39)	R291L	probably damaging	Het
Micu1	C	T	10: 59,568,983 (GRCm39)		probably benign	Het
Msh5	C	T	17: 35,248,928 (GRCm39)	V702I	probably benign	Het
Myh1	T	C	11: 67,101,996 (GRCm39)	I792T	probably benign	Het
Nav1	T	A	1: 135,534,967 (GRCm39)		probably benign	Het
Ntn4	C	T	10: 93,543,215 (GRCm39)	R314W	probably damaging	Het
Or11i1	C	T	3: 106,729,688 (GRCm39)	M62I	probably damaging	Het
Or5ac22	A	G	16: 59,135,027 (GRCm39)	S248P	probably damaging	Het
Or8u9	T	C	2: 86,001,354 (GRCm39)	D269G	probably benign	Het
Otof	G	C	5: 30,551,532 (GRCm39)	N340K	probably benign	Het
Pdlim2	C	T	14: 70,402,228 (GRCm39)	R296H	probably damaging	Het
Plek2	T	A	12: 78,941,664 (GRCm39)	Y155F	probably damaging	Het
Ppa1	T	A	10: 61,487,388 (GRCm39)	Y38*	probably null	Het
Pramel22	T	A	4: 143,381,025 (GRCm39)	T333S	probably damaging	Het
Prmt9	T	A	8: 78,303,968 (GRCm39)	C684S	possibly damaging	Het
Rasl10a	A	G	11: 5,009,473 (GRCm39)	D87G	possibly damaging	Het
Rtn4rl1	C	A	11: 75,156,864 (GRCm39)	P432Q	probably benign	Het
Scd4	T	G	19: 44,329,823 (GRCm39)	Y265D	probably damaging	Het
Scn5a	C	T	9: 119,358,085 (GRCm39)	A719T	probably benign	Het
Sdk1	T	A	5: 142,171,040 (GRCm39)	F1968I	probably benign	Het
Sh3bp5	T	C	14: 31,157,880 (GRCm39)	E12G	probably benign	Het
Slc6a12	T	A	6: 121,337,485 (GRCm39)	F390I	probably benign	Het
Snapin	A	T	3: 90,397,539 (GRCm39)	D77E	possibly damaging	Het
Sox2	G	T	3: 34,704,820 (GRCm39)	E86*	probably null	Het
Sparcl1	A	G	5: 104,241,220 (GRCm39)	L68P	probably benign	Het
Sptb	T	A	12: 76,669,027 (GRCm39)	E562V	probably damaging	Het
Taar3	A	T	10: 23,826,483 (GRCm39)	H343L	probably benign	Het
Tanc1	T	A	2: 59,555,095 (GRCm39)	V51E	possibly damaging	Het
Tbc1d22a	T	C	15: 86,123,350 (GRCm39)	S128P	probably damaging	Het
Thada	A	G	17: 84,751,927 (GRCm39)	S350P	probably benign	Het
Tmem161b	T	C	13: 84,408,348 (GRCm39)	V93A	probably benign	Het
Tnn	T	C	1: 159,924,799 (GRCm39)	Y1185C	probably damaging	Het
Trim43a	T	C	9: 88,464,371 (GRCm39)	V94A	probably benign	Het
Ttll12	C	T	15: 83,465,976 (GRCm39)	E407K	probably benign	Het
Ttn	T	C	2: 76,555,856 (GRCm39)	E30383G	probably damaging	Het
Vmn1r29	T	A	6: 58,285,087 (GRCm39)	M269K	possibly damaging	Het
Vmn2r117	A	G	17: 23,697,363 (GRCm39)	S110P	probably benign	Het
Vmn2r6	C	A	3: 64,463,698 (GRCm39)	V290L	possibly damaging	Het
Vmn2r8	A	T	5: 108,950,019 (GRCm39)	L276Q	probably damaging	Het
Zan	C	A	5: 137,423,904 (GRCm39)	C2665F	unknown	Het
Zfp507	C	T	7: 35,493,150 (GRCm39)	R631Q	probably damaging	Het
Zfp983	A	G	17: 21,880,933 (GRCm39)	H287R	probably damaging	Het

Other mutations in Dnhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Dnhd1	APN	7	105,327,202 (GRCm39)	missense	probably damaging	1.00
IGL00516:Dnhd1	APN	7	105,306,418 (GRCm39)	missense	possibly damaging	0.52
IGL00576:Dnhd1	APN	7	105,341,882 (GRCm39)	missense	probably damaging	1.00
IGL00990:Dnhd1	APN	7	105,370,895 (GRCm39)	missense	possibly damaging	0.85
IGL01346:Dnhd1	APN	7	105,363,116 (GRCm39)	missense	probably benign
IGL01714:Dnhd1	APN	7	105,370,149 (GRCm39)	missense	probably damaging	1.00
IGL01735:Dnhd1	APN	7	105,362,961 (GRCm39)	missense	probably benign	0.37
IGL01814:Dnhd1	APN	7	105,301,237 (GRCm39)	missense	probably benign
IGL01999:Dnhd1	APN	7	105,370,422 (GRCm39)	missense	possibly damaging	0.50
IGL02022:Dnhd1	APN	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
IGL02131:Dnhd1	APN	7	105,370,009 (GRCm39)	missense	probably damaging	1.00
IGL02156:Dnhd1	APN	7	105,370,951 (GRCm39)	missense	probably damaging	1.00
IGL02674:Dnhd1	APN	7	105,370,688 (GRCm39)	missense	probably benign	0.00
IGL02966:Dnhd1	APN	7	105,369,948 (GRCm39)	missense	probably benign	0.00
IGL03066:Dnhd1	APN	7	105,369,089 (GRCm39)	missense	probably damaging	0.99
IGL03298:Dnhd1	APN	7	105,363,682 (GRCm39)	missense	probably damaging	0.98
IGL03378:Dnhd1	APN	7	105,362,940 (GRCm39)	missense	possibly damaging	0.87
IGL02802:Dnhd1	UTSW	7	105,304,930 (GRCm39)	missense	possibly damaging	0.83
R0060:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	0.99
R0129:Dnhd1	UTSW	7	105,370,131 (GRCm39)	missense	probably benign	0.19
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0384:Dnhd1	UTSW	7	105,369,321 (GRCm39)	missense	possibly damaging	0.56
R0453:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R0540:Dnhd1	UTSW	7	105,369,995 (GRCm39)	missense	probably benign	0.04
R0554:Dnhd1	UTSW	7	105,343,602 (GRCm39)	missense	probably benign	0.10
R0576:Dnhd1	UTSW	7	105,363,252 (GRCm39)	missense	probably damaging	1.00
R0607:Dnhd1	UTSW	7	105,369,995 (GRCm39)	missense	probably benign	0.04
R0631:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R0639:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0668:Dnhd1	UTSW	7	105,344,958 (GRCm39)	missense	probably benign
R0669:Dnhd1	UTSW	7	105,342,911 (GRCm39)	missense	probably benign	0.01
R0670:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0699:Dnhd1	UTSW	7	105,301,113 (GRCm39)	missense	probably damaging	0.98
R1019:Dnhd1	UTSW	7	105,358,378 (GRCm39)	missense	probably damaging	1.00
R1144:Dnhd1	UTSW	7	105,362,238 (GRCm39)	missense	probably damaging	1.00
R1226:Dnhd1	UTSW	7	105,346,106 (GRCm39)	missense	probably damaging	1.00
R1257:Dnhd1	UTSW	7	105,343,360 (GRCm39)	missense	probably damaging	1.00
R1391:Dnhd1	UTSW	7	105,369,331 (GRCm39)	missense	probably damaging	1.00
R1453:Dnhd1	UTSW	7	105,370,480 (GRCm39)	critical splice donor site	probably null
R1501:Dnhd1	UTSW	7	105,317,670 (GRCm39)	missense	probably benign	0.00
R1503:Dnhd1	UTSW	7	105,342,867 (GRCm39)	missense	possibly damaging	0.67
R1515:Dnhd1	UTSW	7	105,353,355 (GRCm39)	missense	probably benign	0.11
R1615:Dnhd1	UTSW	7	105,362,913 (GRCm39)	missense	possibly damaging	0.74
R1615:Dnhd1	UTSW	7	105,352,413 (GRCm39)	missense	probably benign	0.00
R1656:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	1.00
R1720:Dnhd1	UTSW	7	105,343,035 (GRCm39)	missense	probably benign
R1723:Dnhd1	UTSW	7	105,364,127 (GRCm39)	missense	possibly damaging	0.60
R1766:Dnhd1	UTSW	7	105,343,179 (GRCm39)	missense	possibly damaging	0.50
R1799:Dnhd1	UTSW	7	105,304,974 (GRCm39)	missense	probably benign	0.31
R1860:Dnhd1	UTSW	7	105,353,412 (GRCm39)	missense	probably benign
R1920:Dnhd1	UTSW	7	105,362,614 (GRCm39)	missense	probably benign	0.00
R1925:Dnhd1	UTSW	7	105,323,061 (GRCm39)	missense	probably damaging	0.96
R1934:Dnhd1	UTSW	7	105,357,789 (GRCm39)	missense	probably benign	0.05
R1935:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R1936:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R2035:Dnhd1	UTSW	7	105,354,128 (GRCm39)	missense	probably damaging	0.99
R2125:Dnhd1	UTSW	7	105,327,178 (GRCm39)	missense	probably benign	0.35
R2127:Dnhd1	UTSW	7	105,342,928 (GRCm39)	missense	possibly damaging	0.56
R2254:Dnhd1	UTSW	7	105,352,979 (GRCm39)	missense	probably damaging	1.00
R2301:Dnhd1	UTSW	7	105,354,606 (GRCm39)	missense	probably damaging	1.00
R2316:Dnhd1	UTSW	7	105,323,628 (GRCm39)	missense	probably damaging	1.00
R2324:Dnhd1	UTSW	7	105,359,297 (GRCm39)	missense	probably damaging	1.00
R2337:Dnhd1	UTSW	7	105,352,674 (GRCm39)	missense	probably benign	0.07
R2381:Dnhd1	UTSW	7	105,342,871 (GRCm39)	missense	probably benign	0.42
R2394:Dnhd1	UTSW	7	105,369,438 (GRCm39)	missense	probably benign	0.19
R2862:Dnhd1	UTSW	7	105,361,766 (GRCm39)	missense	probably benign	0.01
R3038:Dnhd1	UTSW	7	105,369,436 (GRCm39)	missense	probably damaging	0.99
R3114:Dnhd1	UTSW	7	105,345,772 (GRCm39)	critical splice donor site	probably null
R3404:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3405:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3439:Dnhd1	UTSW	7	105,343,992 (GRCm39)	missense	probably damaging	1.00
R3959:Dnhd1	UTSW	7	105,362,329 (GRCm39)	missense	probably benign	0.21
R4014:Dnhd1	UTSW	7	105,364,045 (GRCm39)	missense	probably damaging	0.99
R4084:Dnhd1	UTSW	7	105,358,795 (GRCm39)	missense	probably damaging	1.00
R4181:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4255:Dnhd1	UTSW	7	105,362,205 (GRCm39)	missense	probably damaging	1.00
R4302:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4440:Dnhd1	UTSW	7	105,345,935 (GRCm39)	nonsense	probably null
R4565:Dnhd1	UTSW	7	105,301,163 (GRCm39)	missense	possibly damaging	0.92
R4569:Dnhd1	UTSW	7	105,306,373 (GRCm39)	splice site	probably null
R4584:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4586:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4590:Dnhd1	UTSW	7	105,363,237 (GRCm39)	missense	probably damaging	1.00
R4593:Dnhd1	UTSW	7	105,364,653 (GRCm39)	missense	probably benign	0.02
R4600:Dnhd1	UTSW	7	105,352,851 (GRCm39)	missense	probably damaging	1.00
R4705:Dnhd1	UTSW	7	105,304,948 (GRCm39)	missense	probably damaging	1.00
R4731:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4732:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4733:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4786:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R4791:Dnhd1	UTSW	7	105,370,324 (GRCm39)	missense	probably damaging	1.00
R4811:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	0.99
R4822:Dnhd1	UTSW	7	105,353,171 (GRCm39)	missense	probably benign	0.00
R4886:Dnhd1	UTSW	7	105,364,015 (GRCm39)	missense	probably benign	0.00
R4890:Dnhd1	UTSW	7	105,306,164 (GRCm39)	missense	possibly damaging	0.47
R4973:Dnhd1	UTSW	7	105,362,840 (GRCm39)	missense	probably benign	0.24
R5007:Dnhd1	UTSW	7	105,362,283 (GRCm39)	missense	probably damaging	1.00
R5048:Dnhd1	UTSW	7	105,342,904 (GRCm39)	missense	probably benign	0.01
R5151:Dnhd1	UTSW	7	105,362,647 (GRCm39)	missense	probably benign	0.22
R5179:Dnhd1	UTSW	7	105,363,759 (GRCm39)	missense	probably damaging	1.00
R5182:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5183:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5185:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5209:Dnhd1	UTSW	7	105,345,667 (GRCm39)	missense	probably benign	0.00
R5225:Dnhd1	UTSW	7	105,353,130 (GRCm39)	missense	possibly damaging	0.73
R5250:Dnhd1	UTSW	7	105,334,968 (GRCm39)	missense	probably damaging	1.00
R5257:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5258:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5273:Dnhd1	UTSW	7	105,363,689 (GRCm39)	missense	probably damaging	0.99
R5288:Dnhd1	UTSW	7	105,363,644 (GRCm39)	missense	possibly damaging	0.94
R5396:Dnhd1	UTSW	7	105,362,891 (GRCm39)	missense	probably benign	0.00
R5453:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R5511:Dnhd1	UTSW	7	105,363,363 (GRCm39)	missense	probably damaging	1.00
R5518:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5523:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5528:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5529:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5561:Dnhd1	UTSW	7	105,364,028 (GRCm39)	missense	probably damaging	0.99
R5681:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5682:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5683:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5684:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5686:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5697:Dnhd1	UTSW	7	105,323,395 (GRCm39)	missense	probably damaging	1.00
R5789:Dnhd1	UTSW	7	105,354,217 (GRCm39)	missense	possibly damaging	0.50
R5790:Dnhd1	UTSW	7	105,304,981 (GRCm39)	missense	probably damaging	1.00
R5814:Dnhd1	UTSW	7	105,369,102 (GRCm39)	missense	possibly damaging	0.69
R5828:Dnhd1	UTSW	7	105,369,388 (GRCm39)	missense	probably benign	0.00
R5852:Dnhd1	UTSW	7	105,344,955 (GRCm39)	missense	probably damaging	1.00
R5883:Dnhd1	UTSW	7	105,369,711 (GRCm39)	missense	probably damaging	0.98
R6115:Dnhd1	UTSW	7	105,363,194 (GRCm39)	missense	probably benign	0.00
R6119:Dnhd1	UTSW	7	105,358,647 (GRCm39)	missense	probably benign	0.18
R6212:Dnhd1	UTSW	7	105,353,255 (GRCm39)	missense	probably damaging	1.00
R6243:Dnhd1	UTSW	7	105,301,216 (GRCm39)	missense	probably damaging	1.00
R6265:Dnhd1	UTSW	7	105,342,577 (GRCm39)	missense	probably benign	0.07
R6332:Dnhd1	UTSW	7	105,343,273 (GRCm39)	missense	probably benign	0.02
R6344:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R6477:Dnhd1	UTSW	7	105,327,093 (GRCm39)	missense	probably benign	0.05
R6642:Dnhd1	UTSW	7	105,353,006 (GRCm39)	missense	probably benign
R6663:Dnhd1	UTSW	7	105,334,899 (GRCm39)	splice site	probably null
R6730:Dnhd1	UTSW	7	105,353,082 (GRCm39)	missense	probably benign	0.00
R6748:Dnhd1	UTSW	7	105,369,844 (GRCm39)	missense	probably benign	0.03
R6833:Dnhd1	UTSW	7	105,352,580 (GRCm39)	missense	probably benign	0.01
R6850:Dnhd1	UTSW	7	105,369,137 (GRCm39)	missense	possibly damaging	0.68
R6853:Dnhd1	UTSW	7	105,352,935 (GRCm39)	missense	probably benign
R6860:Dnhd1	UTSW	7	105,327,473 (GRCm39)	missense	probably benign
R6898:Dnhd1	UTSW	7	105,336,584 (GRCm39)	missense	probably damaging	0.99
R6927:Dnhd1	UTSW	7	105,364,770 (GRCm39)	missense	probably damaging	1.00
R6952:Dnhd1	UTSW	7	105,362,895 (GRCm39)	missense	probably damaging	1.00
R6987:Dnhd1	UTSW	7	105,353,792 (GRCm39)	missense	probably damaging	0.98
R6988:Dnhd1	UTSW	7	105,363,417 (GRCm39)	missense	probably damaging	1.00
R7022:Dnhd1	UTSW	7	105,370,005 (GRCm39)	missense	probably benign	0.36
R7053:Dnhd1	UTSW	7	105,344,161 (GRCm39)	missense	probably damaging	1.00
R7085:Dnhd1	UTSW	7	105,364,468 (GRCm39)	missense	probably benign	0.26
R7086:Dnhd1	UTSW	7	105,357,739 (GRCm39)	missense	probably benign	0.03
R7112:Dnhd1	UTSW	7	105,363,192 (GRCm39)	missense	probably damaging	1.00
R7140:Dnhd1	UTSW	7	105,342,973 (GRCm39)	missense	probably benign	0.00
R7151:Dnhd1	UTSW	7	105,359,234 (GRCm39)	missense	probably benign	0.03
R7178:Dnhd1	UTSW	7	105,344,200 (GRCm39)	missense	probably damaging	0.98
R7326:Dnhd1	UTSW	7	105,370,137 (GRCm39)	missense	probably damaging	0.96
R7345:Dnhd1	UTSW	7	105,353,174 (GRCm39)	missense	probably benign	0.17
R7349:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R7397:Dnhd1	UTSW	7	105,354,504 (GRCm39)	missense	possibly damaging	0.87
R7520:Dnhd1	UTSW	7	105,345,255 (GRCm39)	missense	probably benign	0.07
R7536:Dnhd1	UTSW	7	105,358,768 (GRCm39)	missense	probably damaging	1.00
R7539:Dnhd1	UTSW	7	105,370,119 (GRCm39)	missense	probably damaging	1.00
R7541:Dnhd1	UTSW	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
R7619:Dnhd1	UTSW	7	105,323,475 (GRCm39)	missense	probably benign	0.01
R7676:Dnhd1	UTSW	7	105,333,294 (GRCm39)	missense	probably benign	0.09
R7689:Dnhd1	UTSW	7	105,363,170 (GRCm39)	missense	probably benign	0.07
R7712:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R7729:Dnhd1	UTSW	7	105,354,472 (GRCm39)	missense	probably damaging	1.00
R7767:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R7768:Dnhd1	UTSW	7	105,370,302 (GRCm39)	missense	possibly damaging	0.87
R7779:Dnhd1	UTSW	7	105,327,122 (GRCm39)	missense	probably benign	0.01
R7879:Dnhd1	UTSW	7	105,352,646 (GRCm39)	missense	probably benign	0.09
R7922:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	1.00
R7951:Dnhd1	UTSW	7	105,327,211 (GRCm39)	missense	probably damaging	1.00
R8259:Dnhd1	UTSW	7	105,343,995 (GRCm39)	missense	probably benign	0.38
R8350:Dnhd1	UTSW	7	105,327,231 (GRCm39)	missense	probably damaging	0.99
R8380:Dnhd1	UTSW	7	105,327,073 (GRCm39)	missense	probably benign	0.31
R8392:Dnhd1	UTSW	7	105,352,550 (GRCm39)	missense	possibly damaging	0.84
R8478:Dnhd1	UTSW	7	105,332,001 (GRCm39)	missense	probably benign	0.00
R8708:Dnhd1	UTSW	7	105,343,487 (GRCm39)	nonsense	probably null
R8767:Dnhd1	UTSW	7	105,301,330 (GRCm39)	missense	probably damaging	1.00
R8825:Dnhd1	UTSW	7	105,343,174 (GRCm39)	missense	possibly damaging	0.95
R8849:Dnhd1	UTSW	7	105,370,723 (GRCm39)	missense	probably benign	0.00
R8903:Dnhd1	UTSW	7	105,362,855 (GRCm39)	nonsense	probably null
R8910:Dnhd1	UTSW	7	105,332,904 (GRCm39)	missense	possibly damaging	0.92
R8940:Dnhd1	UTSW	7	105,363,854 (GRCm39)	intron	probably benign
R8954:Dnhd1	UTSW	7	105,343,986 (GRCm39)	missense	probably benign	0.35
R8956:Dnhd1	UTSW	7	105,341,852 (GRCm39)	missense	probably damaging	0.99
R8971:Dnhd1	UTSW	7	105,358,528 (GRCm39)	nonsense	probably null
R8996:Dnhd1	UTSW	7	105,323,242 (GRCm39)	missense	probably damaging	1.00
R9051:Dnhd1	UTSW	7	105,341,933 (GRCm39)	missense	possibly damaging	0.54
R9058:Dnhd1	UTSW	7	105,333,270 (GRCm39)	missense	probably benign	0.01
R9109:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9284:Dnhd1	UTSW	7	105,301,091 (GRCm39)	missense	probably damaging	1.00
R9295:Dnhd1	UTSW	7	105,363,348 (GRCm39)	missense	probably benign
R9298:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9299:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9308:Dnhd1	UTSW	7	105,353,484 (GRCm39)	missense	probably damaging	1.00
R9337:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9385:Dnhd1	UTSW	7	105,361,972 (GRCm39)	missense	probably damaging	1.00
R9463:Dnhd1	UTSW	7	105,344,223 (GRCm39)	missense	probably benign
R9463:Dnhd1	UTSW	7	105,306,454 (GRCm39)	missense	probably benign	0.00
R9476:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9489:Dnhd1	UTSW	7	105,300,804 (GRCm39)	missense	probably benign
R9500:Dnhd1	UTSW	7	105,353,709 (GRCm39)	missense	probably benign
R9510:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9513:Dnhd1	UTSW	7	105,354,179 (GRCm39)	missense	probably damaging	1.00
R9537:Dnhd1	UTSW	7	105,344,740 (GRCm39)	missense	probably damaging	0.99
R9567:Dnhd1	UTSW	7	105,353,473 (GRCm39)	missense	probably benign	0.03
R9622:Dnhd1	UTSW	7	105,353,342 (GRCm39)	missense	probably benign
R9623:Dnhd1	UTSW	7	105,344,134 (GRCm39)	missense	probably damaging	1.00
R9623:Dnhd1	UTSW	7	105,335,773 (GRCm39)	missense	probably damaging	1.00
R9674:Dnhd1	UTSW	7	105,363,429 (GRCm39)	missense	probably damaging	1.00
R9756:Dnhd1	UTSW	7	105,353,135 (GRCm39)	missense	probably benign	0.19
R9777:Dnhd1	UTSW	7	105,369,456 (GRCm39)	missense	probably benign	0.14
R9778:Dnhd1	UTSW	7	105,353,240 (GRCm39)	missense	probably benign
R9781:Dnhd1	UTSW	7	105,352,917 (GRCm39)	missense	probably benign	0.31
R9796:Dnhd1	UTSW	7	105,342,537 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnhd1	UTSW	7	105,361,934 (GRCm39)	missense	probably benign	0.00
Z1176:Dnhd1	UTSW	7	105,352,243 (GRCm39)	critical splice acceptor site	probably null
Z1176:Dnhd1	UTSW	7	105,327,506 (GRCm39)	missense	probably benign
Z1176:Dnhd1	UTSW	7	105,317,754 (GRCm39)	missense	probably damaging	0.98
Z1176:Dnhd1	UTSW	7	105,352,787 (GRCm39)	frame shift	probably null
Z1177:Dnhd1	UTSW	7	105,332,048 (GRCm39)	missense	possibly damaging	0.90

Predicted Primers

PCR Primer
(F):5'- AAGAGGTTTCATCGAGGGC -3'
(R):5'- TCACTTTAGAGGTGGGCTAATCC -3'

Sequencing Primer
(F):5'- CAGCATGCCCTTTTGTGAAG -3'
(R):5'- TGGGCTAATCCTGAAGAGCC -3'

Posted On

2014-07-14