Incidental Mutation 'R1937:Sphkap'
| ID |
213492 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sphkap
|
| Ensembl Gene |
ENSMUSG00000026163 |
| Gene Name |
SPHK1 interactor, AKAP domain containing |
| Synonyms |
SKIP, A930009L15Rik, 4930544G21Rik |
| MMRRC Submission |
039955-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.074)
|
| Stock # |
R1937 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
83233163-83385853 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to A
at 83245162 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Stop codon
at position 1486
(E1486*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124872
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159078]
[ENSMUST00000160953]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000053075
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159078
AA Change: E1199*
|
| SMART Domains |
Protein: ENSMUSP00000124384
Gene: ENSMUSG00000026163
AA Change: E1199*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
303 |
314 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
382 |
462 |
5e-3 |
SMART |
|
low complexity region
|
809 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1221 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1254 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1281 |
1398 |
7.5e-13 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000160953
AA Change: E1486*
|
| SMART Domains |
Protein: ENSMUSP00000124872
Gene: ENSMUSG00000026163
AA Change: E1486*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
590 |
601 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
669 |
749 |
6e-3 |
SMART |
|
low complexity region
|
1096 |
1106 |
N/A |
INTRINSIC |
|
low complexity region
|
1141 |
1152 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1508 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1540 |
1655 |
6.4e-12 |
PFAM |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.7%
- 20x: 93.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5730480H06Rik |
C |
A |
5: 48,531,777 (GRCm39) |
T35K |
probably benign |
Het |
| Abhd14a |
A |
G |
9: 106,317,446 (GRCm39) |
|
probably benign |
Het |
| Abhd8 |
A |
G |
8: 71,914,506 (GRCm39) |
F41L |
possibly damaging |
Het |
| Ace2 |
A |
T |
X: 162,939,524 (GRCm39) |
M123L |
possibly damaging |
Het |
| Actr5 |
T |
C |
2: 158,477,949 (GRCm39) |
Y440H |
possibly damaging |
Het |
| Akr1c6 |
T |
A |
13: 4,496,383 (GRCm39) |
N81K |
probably benign |
Het |
| Aqp11 |
T |
A |
7: 97,386,725 (GRCm39) |
N157I |
possibly damaging |
Het |
| Arhgap10 |
T |
C |
8: 78,071,282 (GRCm39) |
E568G |
probably damaging |
Het |
| Asb7 |
T |
A |
7: 66,329,001 (GRCm39) |
Q13L |
probably benign |
Het |
| Atf7ip |
C |
A |
6: 136,537,778 (GRCm39) |
A345E |
probably benign |
Het |
| Atp8a2 |
T |
C |
14: 60,097,719 (GRCm39) |
K770E |
probably benign |
Het |
| Bpifb4 |
A |
T |
2: 153,785,996 (GRCm39) |
I259F |
probably damaging |
Het |
| Cand1 |
A |
T |
10: 119,038,925 (GRCm39) |
D1218E |
probably damaging |
Het |
| Capg |
A |
G |
6: 72,535,236 (GRCm39) |
|
probably null |
Het |
| Cep290 |
C |
T |
10: 100,333,815 (GRCm39) |
T289M |
possibly damaging |
Het |
| Cfap69 |
T |
C |
5: 5,643,818 (GRCm39) |
Y548C |
probably damaging |
Het |
| Cfap97d1 |
A |
T |
11: 101,877,989 (GRCm39) |
H17L |
probably damaging |
Het |
| Cimip2b |
T |
A |
4: 43,427,586 (GRCm39) |
K220N |
probably damaging |
Het |
| Clock |
A |
G |
5: 76,377,340 (GRCm39) |
L652P |
probably damaging |
Het |
| Col3a1 |
C |
T |
1: 45,373,453 (GRCm39) |
|
probably benign |
Het |
| Coro7 |
T |
C |
16: 4,446,596 (GRCm39) |
E843G |
probably benign |
Het |
| Crebrf |
T |
C |
17: 26,961,442 (GRCm39) |
S188P |
probably damaging |
Het |
| Crppa |
G |
A |
12: 36,440,367 (GRCm39) |
V92I |
probably benign |
Het |
| Cul1 |
T |
C |
6: 47,485,289 (GRCm39) |
F307L |
probably benign |
Het |
| Cyb561d2 |
G |
A |
9: 107,417,515 (GRCm39) |
R79W |
probably damaging |
Het |
| Cyp3a59 |
T |
C |
5: 146,031,187 (GRCm39) |
S117P |
possibly damaging |
Het |
| Ddias |
A |
G |
7: 92,507,830 (GRCm39) |
I695T |
probably benign |
Het |
| Dhx29 |
G |
A |
13: 113,101,864 (GRCm39) |
G1311D |
probably benign |
Het |
| Dync2h1 |
A |
G |
9: 7,139,159 (GRCm39) |
|
probably null |
Het |
| Ece2 |
T |
A |
16: 20,436,616 (GRCm39) |
V146E |
probably damaging |
Het |
| Eml2 |
A |
G |
7: 18,937,889 (GRCm39) |
K586E |
possibly damaging |
Het |
| Eps8l3 |
A |
G |
3: 107,791,708 (GRCm39) |
E316G |
probably benign |
Het |
| Fam135b |
A |
T |
15: 71,493,863 (GRCm39) |
L22H |
probably damaging |
Het |
| Focad |
T |
A |
4: 88,319,318 (GRCm39) |
M1K |
probably null |
Het |
| Fryl |
A |
G |
5: 73,290,710 (GRCm39) |
S65P |
probably damaging |
Het |
| Gm14190 |
C |
T |
11: 99,581,556 (GRCm39) |
C4Y |
unknown |
Het |
| H2-T5 |
T |
A |
17: 36,478,899 (GRCm39) |
T117S |
probably damaging |
Het |
| Ift74 |
T |
A |
4: 94,550,883 (GRCm39) |
M345K |
probably benign |
Het |
| Jag1 |
C |
G |
2: 136,925,393 (GRCm39) |
V1070L |
possibly damaging |
Het |
| Kcng1 |
T |
C |
2: 168,104,941 (GRCm39) |
T302A |
probably benign |
Het |
| Kif20b |
T |
C |
19: 34,930,278 (GRCm39) |
V1221A |
possibly damaging |
Het |
| Kif23 |
A |
T |
9: 61,853,892 (GRCm39) |
|
probably null |
Het |
| Lpxn |
T |
G |
19: 12,802,274 (GRCm39) |
S200A |
probably benign |
Het |
| Meiob |
A |
G |
17: 25,037,305 (GRCm39) |
H61R |
probably benign |
Het |
| Mfhas1 |
C |
T |
8: 36,056,799 (GRCm39) |
L425F |
probably damaging |
Het |
| Myo3a |
A |
T |
2: 22,401,126 (GRCm39) |
S632C |
probably damaging |
Het |
| Naip2 |
T |
C |
13: 100,298,362 (GRCm39) |
E558G |
probably benign |
Het |
| Naip2 |
C |
T |
13: 100,298,368 (GRCm39) |
G556D |
probably benign |
Het |
| Nbeal1 |
T |
A |
1: 60,307,100 (GRCm39) |
Y374* |
probably null |
Het |
| Notch3 |
T |
C |
17: 32,372,826 (GRCm39) |
S582G |
probably benign |
Het |
| Nphs1 |
A |
T |
7: 30,173,798 (GRCm39) |
Q985L |
probably damaging |
Het |
| Oas1c |
T |
A |
5: 120,941,049 (GRCm39) |
H248L |
probably benign |
Het |
| Or5c1 |
A |
T |
2: 37,221,896 (GRCm39) |
N46Y |
probably damaging |
Het |
| Or5g26 |
T |
C |
2: 85,494,341 (GRCm39) |
I146V |
probably benign |
Het |
| Or5h25 |
A |
T |
16: 58,930,157 (GRCm39) |
M272K |
probably benign |
Het |
| Or8g35 |
A |
G |
9: 39,381,333 (GRCm39) |
S230P |
possibly damaging |
Het |
| Pamr1 |
A |
T |
2: 102,472,617 (GRCm39) |
I639F |
possibly damaging |
Het |
| Panx1 |
G |
T |
9: 14,918,980 (GRCm39) |
T293K |
possibly damaging |
Het |
| Papss1 |
G |
T |
3: 131,305,632 (GRCm39) |
V226F |
probably benign |
Het |
| Pax1 |
G |
T |
2: 147,209,809 (GRCm39) |
G301V |
possibly damaging |
Het |
| Pdlim5 |
C |
A |
3: 141,950,742 (GRCm39) |
R557L |
possibly damaging |
Het |
| Pdyn |
C |
A |
2: 129,531,729 (GRCm39) |
M20I |
probably benign |
Het |
| Pelp1 |
G |
A |
11: 70,284,541 (GRCm39) |
|
probably null |
Het |
| Pkd2 |
T |
C |
5: 104,626,790 (GRCm39) |
V324A |
probably damaging |
Het |
| Pkdrej |
A |
G |
15: 85,703,368 (GRCm39) |
I856T |
probably benign |
Het |
| Polr1a |
T |
C |
6: 71,913,536 (GRCm39) |
|
probably null |
Het |
| Pot1a |
A |
T |
6: 25,753,323 (GRCm39) |
D404E |
probably benign |
Het |
| Ppp2r2a |
A |
T |
14: 67,253,878 (GRCm39) |
I430N |
possibly damaging |
Het |
| Prob1 |
C |
T |
18: 35,787,279 (GRCm39) |
R325Q |
possibly damaging |
Het |
| Prrc2a |
T |
C |
17: 35,376,884 (GRCm39) |
D742G |
probably damaging |
Het |
| Psmc1 |
C |
T |
12: 100,081,102 (GRCm39) |
P54S |
probably benign |
Het |
| Rab22a |
A |
G |
2: 173,530,004 (GRCm39) |
T61A |
probably damaging |
Het |
| Rims1 |
T |
A |
1: 22,358,754 (GRCm39) |
K184N |
probably damaging |
Het |
| Rnf213 |
G |
A |
11: 119,322,511 (GRCm39) |
R1376H |
probably damaging |
Het |
| Ryr2 |
T |
C |
13: 11,683,848 (GRCm39) |
E3072G |
probably damaging |
Het |
| Serpina1b |
T |
C |
12: 103,698,420 (GRCm39) |
K143R |
probably benign |
Het |
| Slc22a15 |
T |
G |
3: 101,787,505 (GRCm39) |
|
probably null |
Het |
| Slc25a14 |
G |
A |
X: 47,740,840 (GRCm39) |
V210I |
probably benign |
Het |
| Slc25a48 |
A |
C |
13: 56,596,811 (GRCm39) |
T31P |
probably damaging |
Het |
| Slc9a3 |
C |
T |
13: 74,314,175 (GRCm39) |
|
probably null |
Het |
| Slx4 |
T |
C |
16: 3,805,030 (GRCm39) |
*105W |
probably null |
Het |
| Smc6 |
A |
G |
12: 11,349,399 (GRCm39) |
N794S |
probably benign |
Het |
| Spata18 |
G |
A |
5: 73,834,307 (GRCm39) |
R387Q |
probably damaging |
Het |
| Srsf6 |
C |
T |
2: 162,776,403 (GRCm39) |
|
probably benign |
Het |
| St8sia1 |
C |
T |
6: 142,909,398 (GRCm39) |
A33T |
probably damaging |
Het |
| Tet2 |
T |
C |
3: 133,194,399 (GRCm39) |
T12A |
possibly damaging |
Het |
| Tmem144 |
G |
T |
3: 79,732,611 (GRCm39) |
S222R |
probably damaging |
Het |
| Tnrc6c |
A |
G |
11: 117,646,849 (GRCm39) |
D1450G |
possibly damaging |
Het |
| Top1 |
A |
T |
2: 160,512,042 (GRCm39) |
K27N |
unknown |
Het |
| Tox2 |
A |
G |
2: 163,067,476 (GRCm39) |
H30R |
probably benign |
Het |
| Tra2b |
T |
C |
16: 22,065,993 (GRCm39) |
|
probably benign |
Het |
| Trio |
A |
T |
15: 27,833,142 (GRCm39) |
V1165E |
probably damaging |
Het |
| Troap |
T |
A |
15: 98,975,269 (GRCm39) |
S145R |
probably damaging |
Het |
| Ttc34 |
G |
A |
4: 154,950,139 (GRCm39) |
A1031T |
possibly damaging |
Het |
| Ttc6 |
C |
T |
12: 57,663,109 (GRCm39) |
P302S |
probably benign |
Het |
| Ubiad1 |
A |
G |
4: 148,528,468 (GRCm39) |
L147P |
probably damaging |
Het |
| Ugt2b35 |
G |
T |
5: 87,149,141 (GRCm39) |
V131F |
probably damaging |
Het |
| Utp25 |
A |
T |
1: 192,804,401 (GRCm39) |
D200E |
probably damaging |
Het |
| Vmn1r167 |
G |
A |
7: 23,204,452 (GRCm39) |
T188I |
probably benign |
Het |
| Vmn1r46 |
G |
T |
6: 89,953,716 (GRCm39) |
M188I |
probably benign |
Het |
| Vmn2r115 |
T |
A |
17: 23,578,388 (GRCm39) |
N620K |
probably damaging |
Het |
| Vmn2r66 |
A |
G |
7: 84,644,344 (GRCm39) |
S689P |
probably damaging |
Het |
| Wipf2 |
C |
T |
11: 98,783,236 (GRCm39) |
R221* |
probably null |
Het |
| Zbtb16 |
T |
C |
9: 48,571,078 (GRCm39) |
S563G |
probably benign |
Het |
| Zfp319 |
T |
C |
8: 96,055,199 (GRCm39) |
T335A |
probably damaging |
Het |
| Zfp418 |
A |
G |
7: 7,185,401 (GRCm39) |
R455G |
possibly damaging |
Het |
|
| Other mutations in Sphkap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00332:Sphkap
|
APN |
1 |
83,258,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00337:Sphkap
|
APN |
1 |
83,317,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00470:Sphkap
|
APN |
1 |
83,255,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL00577:Sphkap
|
APN |
1 |
83,256,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00657:Sphkap
|
APN |
1 |
83,254,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01868:Sphkap
|
APN |
1 |
83,258,120 (GRCm39) |
splice site |
probably null |
|
|
IGL02101:Sphkap
|
APN |
1 |
83,268,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02471:Sphkap
|
APN |
1 |
83,253,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02945:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03008:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03031:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03059:Sphkap
|
APN |
1 |
83,234,963 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03085:Sphkap
|
APN |
1 |
83,258,075 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03355:Sphkap
|
APN |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03356:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03368:Sphkap
|
APN |
1 |
83,253,397 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0294:Sphkap
|
UTSW |
1 |
83,255,966 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0308:Sphkap
|
UTSW |
1 |
83,254,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0478:Sphkap
|
UTSW |
1 |
83,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Sphkap
|
UTSW |
1 |
83,258,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0678:Sphkap
|
UTSW |
1 |
83,256,349 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1216:Sphkap
|
UTSW |
1 |
83,268,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1253:Sphkap
|
UTSW |
1 |
83,256,619 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1532:Sphkap
|
UTSW |
1 |
83,234,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Sphkap
|
UTSW |
1 |
83,256,121 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1655:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1657:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1701:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1734:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1736:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1743:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1744:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1760:Sphkap
|
UTSW |
1 |
83,255,265 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1893:Sphkap
|
UTSW |
1 |
83,256,687 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1986:Sphkap
|
UTSW |
1 |
83,255,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1993:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1995:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R2001:Sphkap
|
UTSW |
1 |
83,254,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2004:Sphkap
|
UTSW |
1 |
83,255,632 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2111:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2112:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2156:Sphkap
|
UTSW |
1 |
83,255,710 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2182:Sphkap
|
UTSW |
1 |
83,254,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Sphkap
|
UTSW |
1 |
83,234,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Sphkap
|
UTSW |
1 |
83,254,833 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3919:Sphkap
|
UTSW |
1 |
83,254,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3980:Sphkap
|
UTSW |
1 |
83,245,215 (GRCm39) |
splice site |
probably null |
|
|
R4130:Sphkap
|
UTSW |
1 |
83,255,619 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4539:Sphkap
|
UTSW |
1 |
83,255,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4602:Sphkap
|
UTSW |
1 |
83,256,782 (GRCm39) |
nonsense |
probably null |
|
|
R4735:Sphkap
|
UTSW |
1 |
83,256,838 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4793:Sphkap
|
UTSW |
1 |
83,255,805 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4849:Sphkap
|
UTSW |
1 |
83,255,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4880:Sphkap
|
UTSW |
1 |
83,266,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5213:Sphkap
|
UTSW |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5277:Sphkap
|
UTSW |
1 |
83,253,885 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5331:Sphkap
|
UTSW |
1 |
83,254,503 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5632:Sphkap
|
UTSW |
1 |
83,256,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5647:Sphkap
|
UTSW |
1 |
83,385,720 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5751:Sphkap
|
UTSW |
1 |
83,253,618 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5935:Sphkap
|
UTSW |
1 |
83,317,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5999:Sphkap
|
UTSW |
1 |
83,245,126 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6232:Sphkap
|
UTSW |
1 |
83,258,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Sphkap
|
UTSW |
1 |
83,256,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Sphkap
|
UTSW |
1 |
83,256,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6602:Sphkap
|
UTSW |
1 |
83,253,479 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6674:Sphkap
|
UTSW |
1 |
83,255,555 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6716:Sphkap
|
UTSW |
1 |
83,339,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6803:Sphkap
|
UTSW |
1 |
83,258,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Sphkap
|
UTSW |
1 |
83,234,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Sphkap
|
UTSW |
1 |
83,385,811 (GRCm39) |
start gained |
probably benign |
|
|
R7170:Sphkap
|
UTSW |
1 |
83,243,706 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7263:Sphkap
|
UTSW |
1 |
83,254,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Sphkap
|
UTSW |
1 |
83,241,547 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7640:Sphkap
|
UTSW |
1 |
83,256,649 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7722:Sphkap
|
UTSW |
1 |
83,256,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7810:Sphkap
|
UTSW |
1 |
83,254,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7887:Sphkap
|
UTSW |
1 |
83,255,133 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7974:Sphkap
|
UTSW |
1 |
83,256,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7990:Sphkap
|
UTSW |
1 |
83,245,066 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8096:Sphkap
|
UTSW |
1 |
83,255,279 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8110:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8125:Sphkap
|
UTSW |
1 |
83,241,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Sphkap
|
UTSW |
1 |
83,255,730 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8245:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8394:Sphkap
|
UTSW |
1 |
83,253,797 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8443:Sphkap
|
UTSW |
1 |
83,255,953 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8508:Sphkap
|
UTSW |
1 |
83,254,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8531:Sphkap
|
UTSW |
1 |
83,254,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Sphkap
|
UTSW |
1 |
83,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8674:Sphkap
|
UTSW |
1 |
83,255,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8682:Sphkap
|
UTSW |
1 |
83,256,997 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8837:Sphkap
|
UTSW |
1 |
83,253,384 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8857:Sphkap
|
UTSW |
1 |
83,258,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8902:Sphkap
|
UTSW |
1 |
83,256,685 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8916:Sphkap
|
UTSW |
1 |
83,255,108 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8944:Sphkap
|
UTSW |
1 |
83,256,927 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9154:Sphkap
|
UTSW |
1 |
83,234,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9579:Sphkap
|
UTSW |
1 |
83,255,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9616:Sphkap
|
UTSW |
1 |
83,254,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9781:Sphkap
|
UTSW |
1 |
83,255,772 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,256,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,254,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,258,163 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,253,754 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Sphkap
|
UTSW |
1 |
83,254,152 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCACTGGACCATAACATGC -3'
(R):5'- GAAAGACTCCACCTGTGACC -3'
Sequencing Primer
(F):5'- GACCATAACATGCATTTTTGGAGTCC -3'
(R):5'- GACCAACATCCTGCCTGGTATG -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation