Mutagenetix > Incidental Mutation

Incidental Mutation 'R1938:Dennd4a'

213708

Institutional Source

Beutler Lab

Gene Symbol

Dennd4a

Ensembl Gene

ENSMUSG00000053641

Gene Name

DENN/MADD domain containing 4A

Synonyms

F730015K02Rik

MMRRC Submission

039956-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.432) question?

Stock #

R1938 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

64811340-64919667 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 64842490 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Arginine at position 121 (Q121R)

Ref Sequence

ENSEMBL: ENSMUSP00000037915 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000038890] [ENSMUST00000213926]

AlphaFold

E9Q8V6

Predicted Effect

probably damaging
Transcript: ENSMUST00000038890
AA Change: Q121R

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: Q121R

Domain	Start	End	E-Value	Type
internal_repeat_1	45	93	3.26e-5	PROSPERO
uDENN	169	276	1.71e-28	SMART
DENN	309	493	2.4e-73	SMART
dDENN	559	633	4.15e-27	SMART
low complexity region	724	735	N/A	INTRINSIC
low complexity region	936	950	N/A	INTRINSIC
low complexity region	1176	1191	N/A	INTRINSIC
low complexity region	1249	1262	N/A	INTRINSIC
low complexity region	1402	1417	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000213437

Predicted Effect

probably benign
Transcript: ENSMUST00000213926

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000214001

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215025

Coding Region Coverage

1x: 97.5%
3x: 96.9%
10x: 95.4%
20x: 92.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]

Allele List at MGI

Other mutations in this stock

Total: 133 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310007B03Rik	T	C	1: 93,152,008 (GRCm38)	*453W	probably null	Het
Abcc8	T	C	7: 46,175,371 (GRCm38)	K134R	possibly damaging	Het
Adamts17	T	C	7: 67,125,072 (GRCm38)	S980P	probably damaging	Het
Adap2	T	A	11: 80,170,682 (GRCm38)	I221K	probably damaging	Het
Adgrv1	C	T	13: 81,391,757 (GRCm38)	R5681Q	probably damaging	Het
Adipor1	T	A	1: 134,423,103 (GRCm38)	L30Q	probably benign	Het
Agpat5	A	G	8: 18,878,165 (GRCm38)	T249A	probably benign	Het
Agxt2	G	T	15: 10,391,935 (GRCm38)	G329V	probably damaging	Het
Ankrd28	A	G	14: 31,705,276 (GRCm38)	V801A	possibly damaging	Het
Ap1g2	A	G	14: 55,099,772 (GRCm38)	V702A	possibly damaging	Het
Arid3a	A	G	10: 79,950,706 (GRCm38)	Q429R	probably damaging	Het
Arsb	T	A	13: 93,862,150 (GRCm38)	L322Q	probably damaging	Het
Ash1l	A	G	3: 88,984,422 (GRCm38)	T1203A	probably damaging	Het
Atad2	T	A	15: 58,096,705 (GRCm38)	N1308Y	possibly damaging	Het
Atp10b	A	T	11: 43,230,418 (GRCm38)	R969S	probably benign	Het
Bmp10	T	C	6: 87,433,720 (GRCm38)	I165T	possibly damaging	Het
Ccne1	A	G	7: 38,106,277 (GRCm38)		probably null	Het
Cenpe	A	G	3: 135,247,479 (GRCm38)	N1565D	probably damaging	Het
Chd1	A	T	17: 15,762,486 (GRCm38)	E1404D	probably benign	Het
Chd7	G	A	4: 8,847,200 (GRCm38)	E1648K	probably damaging	Het
Chodl	T	C	16: 78,941,426 (GRCm38)	I94T	possibly damaging	Het
Chsy3	T	C	18: 59,409,512 (GRCm38)	F574S	probably damaging	Het
Clpb	A	T	7: 101,763,656 (GRCm38)	I317F	probably damaging	Het
Cnga3	T	A	1: 37,261,873 (GRCm38)	V558D	possibly damaging	Het
Col9a1	C	T	1: 24,222,473 (GRCm38)	P573S	probably damaging	Het
Crat	A	T	2: 30,413,061 (GRCm38)	D71E	probably benign	Het
Cspg4	A	G	9: 56,887,101 (GRCm38)	T707A	probably benign	Het
Ctsr	T	A	13: 61,162,445 (GRCm38)	R132S	probably benign	Het
Ctu2	T	C	8: 122,479,285 (GRCm38)	L255P	probably damaging	Het
Cyp2c69	T	C	19: 39,849,366 (GRCm38)	Y424C	probably damaging	Het
Ddx27	A	T	2: 167,034,109 (GRCm38)	K726N	probably damaging	Het
Dis3	A	G	14: 99,097,590 (GRCm38)	F192S	probably benign	Het
Ect2l	C	T	10: 18,144,635 (GRCm38)	S487N	probably benign	Het
Eml1	T	A	12: 108,521,396 (GRCm38)	F524L	possibly damaging	Het
Espl1	T	C	15: 102,305,042 (GRCm38)	I601T	probably benign	Het
Fbxo40	C	A	16: 36,969,351 (GRCm38)	V466L	probably damaging	Het
Frmpd1	C	T	4: 45,283,711 (GRCm38)	T844M	probably damaging	Het
Frs2	T	A	10: 117,081,106 (GRCm38)		probably benign	Het
Fuom	G	T	7: 140,099,608 (GRCm38)	T133K	probably benign	Het
Garnl3	T	A	2: 33,005,200 (GRCm38)	H619L	probably damaging	Het
Gm4861	G	T	3: 137,552,115 (GRCm38)	N36K	unknown	Het
Gm6588	C	A	5: 112,449,801 (GRCm38)	C71*	probably null	Het
Gps2	G	T	11: 69,915,369 (GRCm38)	M153I	probably benign	Het
Gtf2ird1	A	G	5: 134,415,245 (GRCm38)	V52A	probably damaging	Het
Gtpbp8	A	T	16: 44,745,422 (GRCm38)	D137E	probably benign	Het
Haus4	A	G	14: 54,544,276 (GRCm38)	C213R	probably damaging	Het
Hdc	T	A	2: 126,606,397 (GRCm38)	H142L	possibly damaging	Het
Hephl1	T	C	9: 15,053,987 (GRCm38)	D1069G	possibly damaging	Het
Herc6	T	A	6: 57,625,941 (GRCm38)	V535D	probably damaging	Het
Hipk3	A	T	2: 104,430,188 (GRCm38)	H1082Q	possibly damaging	Het
Hps5	A	T	7: 46,773,267 (GRCm38)	V513D	probably damaging	Het
Ifna13	T	A	4: 88,644,175 (GRCm38)	I71F	probably damaging	Het
Il1rl2	T	C	1: 40,363,324 (GRCm38)	I426T	probably damaging	Het
Irf5	A	T	6: 29,536,739 (GRCm38)	D483V	probably benign	Het
Jakmip3	A	G	7: 139,020,138 (GRCm38)	R256G	probably damaging	Het
Jazf1	T	C	6: 52,777,615 (GRCm38)	I159V	probably damaging	Het
Kmo	A	G	1: 175,651,588 (GRCm38)	D230G	possibly damaging	Het
Lrrc74b	A	G	16: 17,553,194 (GRCm38)	V213A	probably benign	Het
Ly6g5b	T	C	17: 35,114,728 (GRCm38)	D36G	possibly damaging	Het
Macc1	T	G	12: 119,445,731 (GRCm38)	L78R	probably damaging	Het
Mettl4	A	T	17: 94,747,857 (GRCm38)	D51E	possibly damaging	Het
Mfap1a	G	A	2: 121,502,354 (GRCm38)	L199F	possibly damaging	Het
Mmp17	G	T	5: 129,602,126 (GRCm38)	R363L	probably damaging	Het
Mrc1	G	A	2: 14,319,241 (GRCm38)	A1130T	possibly damaging	Het
Mrpl15	C	T	1: 4,777,582 (GRCm38)	A165T	probably damaging	Het
Mrpl45	G	A	11: 97,315,944 (GRCm38)		probably null	Het
Ms4a3	C	T	19: 11,635,840 (GRCm38)	A85T	possibly damaging	Het
Mttp	A	T	3: 138,125,121 (GRCm38)	D77E	probably benign	Het
Muc6	A	G	7: 141,637,098 (GRCm38)	L2489P	probably damaging	Het
Myl3	G	A	9: 110,766,734 (GRCm38)	E100K	probably damaging	Het
Nbea	T	A	3: 56,085,322 (GRCm38)	N288Y	probably damaging	Het
Ncoa7	A	G	10: 30,698,170 (GRCm38)	V181A	probably benign	Het
Oat	C	T	7: 132,558,205 (GRCm38)	V429M	probably benign	Het
Olfr1152	G	A	2: 87,868,461 (GRCm38)	V157I	probably benign	Het
Olfr1163	A	T	2: 88,070,956 (GRCm38)	L142Q	probably damaging	Het
Olfr1269	T	G	2: 90,119,083 (GRCm38)	I172L	probably damaging	Het
Olfr285	T	A	15: 98,313,380 (GRCm38)	M57L	probably damaging	Het
Olfr319	A	T	11: 58,702,623 (GRCm38)	*307C	probably null	Het
Olfr508	T	C	7: 108,630,838 (GRCm38)	I282T	probably benign	Het
Olfr524	A	G	7: 140,202,231 (GRCm38)	F180L	probably benign	Het
Olfr810	T	A	10: 129,790,890 (GRCm38)	K233M	probably damaging	Het
Olfr922	A	G	9: 38,815,850 (GRCm38)	T116A	probably benign	Het
Oraov1	A	G	7: 144,916,468 (GRCm38)	S45G	probably damaging	Het
Otof	A	G	5: 30,376,369 (GRCm38)	S1464P	probably benign	Het
Otogl	A	T	10: 107,777,575 (GRCm38)	Y2010N	probably damaging	Het
Pgap3	C	T	11: 98,400,214 (GRCm38)		probably null	Het
Pgbd5	T	A	8: 124,374,249 (GRCm38)	K332*	probably null	Het
Pgs1	C	T	11: 118,005,727 (GRCm38)	P410L	probably damaging	Het
Pkhd1l1	G	A	15: 44,500,038 (GRCm38)	S618N	probably benign	Het
Plcb1	A	T	2: 135,386,302 (GRCm38)	D1073V	probably damaging	Het
Pola2	T	A	19: 5,951,180 (GRCm38)	T309S	probably benign	Het
Polg2	T	A	11: 106,778,961 (GRCm38)	H161L	probably damaging	Het
Postn	T	A	3: 54,377,612 (GRCm38)		probably null	Het
Ppt1	G	T	4: 122,845,991 (GRCm38)	C128F	probably damaging	Het
Ptpn12	G	A	5: 20,993,263 (GRCm38)	P678S	probably damaging	Het
Rcan3	A	T	4: 135,412,501 (GRCm38)		probably null	Het
Rgs22	T	C	15: 36,101,804 (GRCm38)	N216S	probably benign	Het
Rgs7bp	T	A	13: 104,951,582 (GRCm38)	D228V	probably damaging	Het
Rhobtb2	A	T	14: 69,796,613 (GRCm38)	S388T	probably benign	Het
Rnps1	C	T	17: 24,420,390 (GRCm38)	R138C	unknown	Het
Rpl38	T	C	11: 114,671,776 (GRCm38)	V36A	probably benign	Het
Rps7	G	T	12: 28,631,753 (GRCm38)	H126Q	possibly damaging	Het
Sec24b	G	T	3: 129,991,361 (GRCm38)	Q999K	possibly damaging	Het
Slc19a3	A	G	1: 83,019,368 (GRCm38)	V373A	possibly damaging	Het
Spats2l	T	A	1: 57,885,782 (GRCm38)	V113E	probably benign	Het
Ss18l1	A	T	2: 180,063,345 (GRCm38)	T377S	unknown	Het
Surf1	A	G	2: 26,915,970 (GRCm38)	F38L	probably benign	Het
Ticrr	G	A	7: 79,675,394 (GRCm38)	R556H	probably damaging	Het
Tmem184b	A	G	15: 79,365,814 (GRCm38)	S254P	probably damaging	Het
Tnfrsf4	G	T	4: 156,016,235 (GRCm38)	R237L	possibly damaging	Het
Tnk2	C	A	16: 32,663,742 (GRCm38)		probably benign	Het
Tnks	A	T	8: 34,838,530 (GRCm38)	D1191E	probably damaging	Het
Tnr	C	A	1: 159,895,037 (GRCm38)	Y1017*	probably null	Het
Tomm34	A	G	2: 164,061,006 (GRCm38)	I128T	probably benign	Het
Trim2	G	A	3: 84,177,792 (GRCm38)	S540F	possibly damaging	Het
Trio	A	T	15: 27,732,891 (GRCm38)	I2968N	probably damaging	Het
Ttc24	T	C	3: 88,074,874 (GRCm38)	E17G	probably benign	Het
Ttc41	A	G	10: 86,776,214 (GRCm38)	H1117R	probably benign	Het
Ttn	A	T	2: 76,762,386 (GRCm38)	S20801T	possibly damaging	Het
Ttn	A	T	2: 76,735,408 (GRCm38)	V28200D	probably damaging	Het
Ube2cbp	C	T	9: 86,448,787 (GRCm38)	C114Y	probably damaging	Het
Ugt2b37	A	C	5: 87,240,857 (GRCm38)	L499R	probably damaging	Het
Vmn1r81	T	C	7: 12,260,662 (GRCm38)	I6M	possibly damaging	Het
Vmn2r97	A	T	17: 18,929,331 (GRCm38)	Y327F	probably benign	Het
Vps13b	T	C	15: 35,709,507 (GRCm38)	S1867P	probably damaging	Het
Wdr11	T	C	7: 129,606,607 (GRCm38)	V362A	probably benign	Het
Zan	T	A	5: 137,388,939 (GRCm38)	M4951L	unknown	Het
Zcwpw1	T	A	5: 137,811,622 (GRCm38)	L337Q	probably damaging	Het
Zfp2	A	T	11: 50,899,982 (GRCm38)	D411E	possibly damaging	Het
Zfp628	C	T	7: 4,920,768 (GRCm38)	T663I	probably benign	Het
Zfpm1	T	A	8: 122,334,924 (GRCm38)		probably null	Het
Zfyve19	T	C	2: 119,211,212 (GRCm38)	S87P	probably benign	Het
Zswim9	T	A	7: 13,260,214 (GRCm38)	K672*	probably null	Het

Other mutations in Dennd4a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00476:Dennd4a	APN	9	64,911,762 (GRCm38)	missense	probably damaging	1.00
IGL01610:Dennd4a	APN	9	64,906,884 (GRCm38)	missense	probably damaging	0.99
IGL01788:Dennd4a	APN	9	64,842,621 (GRCm38)	missense	probably benign	0.00
IGL01827:Dennd4a	APN	9	64,842,561 (GRCm38)	nonsense	probably null
IGL01828:Dennd4a	APN	9	64,842,561 (GRCm38)	nonsense	probably null
IGL01829:Dennd4a	APN	9	64,842,561 (GRCm38)	nonsense	probably null
IGL01979:Dennd4a	APN	9	64,894,409 (GRCm38)	missense	probably benign	0.00
IGL02100:Dennd4a	APN	9	64,909,706 (GRCm38)	splice site	probably benign
IGL02339:Dennd4a	APN	9	64,842,561 (GRCm38)	nonsense	probably null
IGL02341:Dennd4a	APN	9	64,842,561 (GRCm38)	nonsense	probably null
IGL02584:Dennd4a	APN	9	64,851,298 (GRCm38)	missense	probably damaging	1.00
IGL02607:Dennd4a	APN	9	64,862,327 (GRCm38)	missense	probably damaging	0.99
IGL02654:Dennd4a	APN	9	64,910,191 (GRCm38)	splice site	probably benign
IGL02701:Dennd4a	APN	9	64,897,353 (GRCm38)	missense	possibly damaging	0.50
IGL03051:Dennd4a	APN	9	64,862,414 (GRCm38)	missense	probably damaging	1.00
IGL03257:Dennd4a	APN	9	64,871,874 (GRCm38)	missense	possibly damaging	0.93
IGL03346:Dennd4a	APN	9	64,888,526 (GRCm38)	missense	possibly damaging	0.47
IGL03349:Dennd4a	APN	9	64,888,974 (GRCm38)	missense	probably damaging	1.00
IGL03398:Dennd4a	APN	9	64,871,882 (GRCm38)	missense	probably benign	0.32
R0010:Dennd4a	UTSW	9	64,896,715 (GRCm38)	missense	probably benign	0.00
R0010:Dennd4a	UTSW	9	64,896,715 (GRCm38)	missense	probably benign	0.00
R0129:Dennd4a	UTSW	9	64,893,294 (GRCm38)	missense	probably damaging	1.00
R0220:Dennd4a	UTSW	9	64,852,445 (GRCm38)	missense	probably damaging	1.00
R0396:Dennd4a	UTSW	9	64,862,391 (GRCm38)	missense	probably damaging	1.00
R0881:Dennd4a	UTSW	9	64,851,383 (GRCm38)	critical splice donor site	probably null
R1225:Dennd4a	UTSW	9	64,911,675 (GRCm38)	missense	probably benign	0.03
R1311:Dennd4a	UTSW	9	64,910,004 (GRCm38)	missense	probably benign	0.34
R1448:Dennd4a	UTSW	9	64,906,045 (GRCm38)	missense	possibly damaging	0.95
R1450:Dennd4a	UTSW	9	64,911,665 (GRCm38)	missense	probably benign	0.03
R1630:Dennd4a	UTSW	9	64,871,882 (GRCm38)	missense	probably benign	0.32
R1709:Dennd4a	UTSW	9	64,889,605 (GRCm38)	missense	possibly damaging	0.92
R1824:Dennd4a	UTSW	9	64,859,358 (GRCm38)	critical splice donor site	probably null
R1851:Dennd4a	UTSW	9	64,862,030 (GRCm38)	missense	probably damaging	1.00
R1870:Dennd4a	UTSW	9	64,897,234 (GRCm38)	missense	probably benign	0.00
R1900:Dennd4a	UTSW	9	64,897,336 (GRCm38)	missense	probably damaging	0.99
R1911:Dennd4a	UTSW	9	64,889,086 (GRCm38)	missense	probably damaging	1.00
R1954:Dennd4a	UTSW	9	64,852,467 (GRCm38)	missense	probably benign	0.02
R1955:Dennd4a	UTSW	9	64,852,467 (GRCm38)	missense	probably benign	0.02
R2049:Dennd4a	UTSW	9	64,889,605 (GRCm38)	missense	possibly damaging	0.92
R2129:Dennd4a	UTSW	9	64,905,974 (GRCm38)	splice site	probably null
R2138:Dennd4a	UTSW	9	64,889,337 (GRCm38)	missense	probably damaging	1.00
R2929:Dennd4a	UTSW	9	64,852,417 (GRCm38)	missense	possibly damaging	0.85
R3083:Dennd4a	UTSW	9	64,906,081 (GRCm38)	missense	probably benign	0.03
R3108:Dennd4a	UTSW	9	64,912,387 (GRCm38)	missense	probably benign	0.23
R3176:Dennd4a	UTSW	9	64,888,993 (GRCm38)	missense	probably damaging	1.00
R3177:Dennd4a	UTSW	9	64,888,993 (GRCm38)	missense	probably damaging	1.00
R3276:Dennd4a	UTSW	9	64,888,993 (GRCm38)	missense	probably damaging	1.00
R3277:Dennd4a	UTSW	9	64,888,993 (GRCm38)	missense	probably damaging	1.00
R3890:Dennd4a	UTSW	9	64,872,028 (GRCm38)	missense	probably damaging	1.00
R3953:Dennd4a	UTSW	9	64,852,575 (GRCm38)	missense	probably damaging	1.00
R3963:Dennd4a	UTSW	9	64,862,331 (GRCm38)	missense	probably damaging	1.00
R4059:Dennd4a	UTSW	9	64,911,892 (GRCm38)	missense	possibly damaging	0.92
R4499:Dennd4a	UTSW	9	64,910,123 (GRCm38)	missense	possibly damaging	0.78
R4500:Dennd4a	UTSW	9	64,910,123 (GRCm38)	missense	possibly damaging	0.78
R4501:Dennd4a	UTSW	9	64,910,123 (GRCm38)	missense	possibly damaging	0.78
R4671:Dennd4a	UTSW	9	64,894,407 (GRCm38)	missense	probably benign
R4701:Dennd4a	UTSW	9	64,897,357 (GRCm38)	missense	possibly damaging	0.91
R4821:Dennd4a	UTSW	9	64,897,249 (GRCm38)	missense	possibly damaging	0.92
R4829:Dennd4a	UTSW	9	64,889,056 (GRCm38)	missense	probably damaging	1.00
R4876:Dennd4a	UTSW	9	64,896,590 (GRCm38)	missense	probably benign
R4881:Dennd4a	UTSW	9	64,838,844 (GRCm38)	missense	possibly damaging	0.77
R4962:Dennd4a	UTSW	9	64,906,003 (GRCm38)	missense	probably benign	0.00
R5225:Dennd4a	UTSW	9	64,888,928 (GRCm38)	missense	possibly damaging	0.94
R5557:Dennd4a	UTSW	9	64,904,227 (GRCm38)	missense	probably benign	0.07
R5649:Dennd4a	UTSW	9	64,851,209 (GRCm38)	splice site	probably null
R5868:Dennd4a	UTSW	9	64,896,729 (GRCm38)	missense	probably benign	0.02
R5876:Dennd4a	UTSW	9	64,911,755 (GRCm38)	missense	probably damaging	1.00
R6052:Dennd4a	UTSW	9	64,886,945 (GRCm38)	missense	probably damaging	1.00
R6411:Dennd4a	UTSW	9	64,871,899 (GRCm38)	missense	probably benign	0.04
R6596:Dennd4a	UTSW	9	64,852,420 (GRCm38)	missense	probably damaging	1.00
R6668:Dennd4a	UTSW	9	64,886,965 (GRCm38)	missense	probably damaging	1.00
R6915:Dennd4a	UTSW	9	64,852,489 (GRCm38)	nonsense	probably null
R7056:Dennd4a	UTSW	9	64,906,923 (GRCm38)	missense	possibly damaging	0.89
R7107:Dennd4a	UTSW	9	64,894,399 (GRCm38)	missense	possibly damaging	0.79
R7203:Dennd4a	UTSW	9	64,896,474 (GRCm38)	missense	probably benign	0.05
R7238:Dennd4a	UTSW	9	64,861,956 (GRCm38)	missense	probably damaging	1.00
R7373:Dennd4a	UTSW	9	64,897,269 (GRCm38)	missense	probably benign	0.01
R7454:Dennd4a	UTSW	9	64,852,570 (GRCm38)	missense	probably damaging	1.00
R7546:Dennd4a	UTSW	9	64,873,044 (GRCm38)	missense	probably damaging	1.00
R7590:Dennd4a	UTSW	9	64,888,587 (GRCm38)	missense	probably benign	0.01
R7662:Dennd4a	UTSW	9	64,852,431 (GRCm38)	missense	probably damaging	1.00
R7782:Dennd4a	UTSW	9	64,906,920 (GRCm38)	missense	probably damaging	0.98
R7909:Dennd4a	UTSW	9	64,872,993 (GRCm38)	critical splice acceptor site	probably null
R7976:Dennd4a	UTSW	9	64,852,512 (GRCm38)	missense	possibly damaging	0.95
R8026:Dennd4a	UTSW	9	64,873,030 (GRCm38)	missense	probably damaging	1.00
R8034:Dennd4a	UTSW	9	64,888,568 (GRCm38)	missense	probably benign	0.01
R8089:Dennd4a	UTSW	9	64,849,175 (GRCm38)	missense	probably damaging	1.00
R8298:Dennd4a	UTSW	9	64,906,875 (GRCm38)	missense	probably benign	0.00
R8397:Dennd4a	UTSW	9	64,889,109 (GRCm38)	missense	probably benign
R8425:Dennd4a	UTSW	9	64,838,974 (GRCm38)	missense	probably damaging	1.00
R8495:Dennd4a	UTSW	9	64,886,879 (GRCm38)	missense	probably damaging	1.00
R8855:Dennd4a	UTSW	9	64,912,390 (GRCm38)	missense	probably benign
R9219:Dennd4a	UTSW	9	64,889,094 (GRCm38)	missense	probably damaging	0.96
R9275:Dennd4a	UTSW	9	64,842,624 (GRCm38)	missense	probably damaging	1.00
R9376:Dennd4a	UTSW	9	64,912,692 (GRCm38)	missense	probably benign	0.00
R9485:Dennd4a	UTSW	9	64,907,106 (GRCm38)	nonsense	probably null
R9672:Dennd4a	UTSW	9	64,893,358 (GRCm38)	missense	probably benign
R9746:Dennd4a	UTSW	9	64,894,511 (GRCm38)	missense	probably benign
X0026:Dennd4a	UTSW	9	64,897,320 (GRCm38)	missense	possibly damaging	0.67
Z1088:Dennd4a	UTSW	9	64,872,022 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CACCCAACTCTTTTGCAGAAG -3'
(R):5'- GTCGACCTTGCAGAATGTGTG -3'

Sequencing Primer
(F):5'- CCCAACTCTTTTGCAGAAGATGGAG -3'
(R):5'- GTGGTGGGCTCTCTCCTTTAC -3'

Posted On

2014-07-14