Incidental Mutation 'R1900:Dennd4a'
| ID |
214205 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
039920-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R1900 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 64897336 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1319
(V1319A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038890
AA Change: V1319A
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: V1319A
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000216098
|
| Meta Mutation Damage Score |
0.1705 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.5%
- 20x: 93.0%
|
| Validation Efficiency |
96% (100/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3632451O06Rik |
T |
C |
14: 49,770,583 (GRCm38) |
T478A |
probably damaging |
Het |
| 6330409D20Rik |
T |
C |
2: 32,740,547 (GRCm38) |
|
probably benign |
Het |
| Ago4 |
T |
C |
4: 126,516,936 (GRCm38) |
I221V |
probably benign |
Het |
| Ankfy1 |
C |
T |
11: 72,754,407 (GRCm38) |
Q771* |
probably null |
Het |
| Ankrd50 |
T |
C |
3: 38,455,387 (GRCm38) |
T944A |
probably damaging |
Het |
| AU040320 |
A |
C |
4: 126,853,280 (GRCm38) |
|
probably null |
Het |
| Axdnd1 |
A |
G |
1: 156,380,774 (GRCm38) |
|
probably null |
Het |
| Cdadc1 |
A |
T |
14: 59,586,532 (GRCm38) |
D170E |
probably damaging |
Het |
| Cep164 |
C |
A |
9: 45,809,825 (GRCm38) |
R93L |
probably damaging |
Het |
| Cep250 |
T |
C |
2: 155,985,374 (GRCm38) |
|
probably null |
Het |
| Cfdp1 |
G |
A |
8: 111,768,729 (GRCm38) |
R286* |
probably null |
Het |
| Chrdl2 |
A |
G |
7: 100,033,664 (GRCm38) |
I377V |
possibly damaging |
Het |
| Cntrob |
A |
T |
11: 69,308,054 (GRCm38) |
S623T |
probably benign |
Het |
| Col6a5 |
C |
T |
9: 105,931,213 (GRCm38) |
G879S |
unknown |
Het |
| Cyp2c38 |
T |
A |
19: 39,438,312 (GRCm38) |
I182F |
probably benign |
Het |
| Dysf |
T |
G |
6: 84,039,567 (GRCm38) |
V70G |
probably damaging |
Het |
| Edn3 |
A |
G |
2: 174,761,605 (GRCm38) |
T49A |
possibly damaging |
Het |
| Elac1 |
C |
G |
18: 73,739,245 (GRCm38) |
L226F |
probably damaging |
Het |
| Eps8l3 |
A |
G |
3: 107,890,952 (GRCm38) |
D445G |
probably benign |
Het |
| Fam71a |
T |
A |
1: 191,164,434 (GRCm38) |
K4M |
possibly damaging |
Het |
| Fgf11 |
G |
T |
11: 69,801,453 (GRCm38) |
T58K |
probably benign |
Het |
| Fstl5 |
T |
A |
3: 76,708,160 (GRCm38) |
W843R |
probably damaging |
Het |
| Fyb2 |
A |
G |
4: 104,945,455 (GRCm38) |
R185G |
probably benign |
Het |
| Gal3st2c |
G |
A |
1: 94,009,044 (GRCm38) |
R237H |
probably damaging |
Het |
| Galnt15 |
G |
T |
14: 32,049,865 (GRCm38) |
R289L |
probably damaging |
Het |
| Gdf5 |
T |
A |
2: 155,942,081 (GRCm38) |
D317V |
probably damaging |
Het |
| Gm10436 |
A |
C |
12: 88,177,260 (GRCm38) |
L261R |
probably benign |
Het |
| Gm7808 |
A |
G |
9: 19,928,114 (GRCm38) |
|
probably benign |
Het |
| Hcn3 |
T |
C |
3: 89,148,263 (GRCm38) |
E559G |
probably benign |
Het |
| Hdlbp |
A |
T |
1: 93,422,237 (GRCm38) |
|
probably benign |
Het |
| Hhip |
T |
C |
8: 79,975,046 (GRCm38) |
T620A |
probably benign |
Het |
| Hs3st3a1 |
T |
C |
11: 64,520,442 (GRCm38) |
S269P |
probably damaging |
Het |
| Il17ra |
A |
T |
6: 120,477,394 (GRCm38) |
|
probably null |
Het |
| Kif2a |
T |
C |
13: 106,976,995 (GRCm38) |
N417S |
possibly damaging |
Het |
| Klhl41 |
T |
A |
2: 69,674,619 (GRCm38) |
|
probably benign |
Het |
| L3mbtl4 |
G |
T |
17: 68,459,805 (GRCm38) |
C169F |
probably damaging |
Het |
| Lap3 |
T |
C |
5: 45,511,910 (GRCm38) |
F467S |
probably damaging |
Het |
| Lpar6 |
A |
T |
14: 73,239,139 (GRCm38) |
Y180F |
probably benign |
Het |
| Lrig3 |
T |
C |
10: 126,002,393 (GRCm38) |
|
probably benign |
Het |
| Ltbp2 |
A |
T |
12: 84,830,658 (GRCm38) |
S378T |
probably damaging |
Het |
| Ltf |
T |
C |
9: 111,022,845 (GRCm38) |
F117L |
possibly damaging |
Het |
| Med16 |
T |
C |
10: 79,898,931 (GRCm38) |
E533G |
probably damaging |
Het |
| Meltf |
T |
C |
16: 31,881,969 (GRCm38) |
|
probably null |
Het |
| Mphosph10 |
C |
T |
7: 64,381,028 (GRCm38) |
E488K |
possibly damaging |
Het |
| Mroh1 |
A |
G |
15: 76,433,385 (GRCm38) |
T812A |
probably benign |
Het |
| Mto1 |
T |
C |
9: 78,461,517 (GRCm38) |
|
probably benign |
Het |
| Ndst1 |
A |
T |
18: 60,712,721 (GRCm38) |
|
probably null |
Het |
| Ndst4 |
T |
A |
3: 125,697,895 (GRCm38) |
|
probably null |
Het |
| Nhlh1 |
A |
T |
1: 172,054,041 (GRCm38) |
I86N |
probably damaging |
Het |
| Nme9 |
A |
C |
9: 99,459,774 (GRCm38) |
D59A |
probably damaging |
Het |
| Nox4 |
A |
T |
7: 87,360,796 (GRCm38) |
R402* |
probably null |
Het |
| Npr1 |
T |
C |
3: 90,462,188 (GRCm38) |
D410G |
probably damaging |
Het |
| Nrip1 |
T |
A |
16: 76,292,039 (GRCm38) |
T877S |
probably benign |
Het |
| Nsd2 |
A |
G |
5: 33,846,169 (GRCm38) |
N221S |
probably benign |
Het |
| Olfr1230 |
T |
C |
2: 89,296,670 (GRCm38) |
N200S |
probably damaging |
Het |
| Olfr1463 |
T |
A |
19: 13,234,913 (GRCm38) |
I221K |
possibly damaging |
Het |
| Olfr23 |
C |
A |
11: 73,940,660 (GRCm38) |
P138Q |
possibly damaging |
Het |
| Olfr250 |
A |
T |
9: 38,368,064 (GRCm38) |
I173L |
probably benign |
Het |
| Olfr561 |
A |
T |
7: 102,775,331 (GRCm38) |
H269L |
probably benign |
Het |
| Olfr61 |
A |
T |
7: 140,638,592 (GRCm38) |
D297V |
probably damaging |
Het |
| Olfr616 |
A |
T |
7: 103,564,607 (GRCm38) |
L224* |
probably null |
Het |
| Ophn1 |
A |
T |
X: 98,726,059 (GRCm38) |
Y181* |
probably null |
Het |
| Parp1 |
A |
G |
1: 180,597,339 (GRCm38) |
K819R |
probably damaging |
Het |
| Parp9 |
T |
C |
16: 35,972,221 (GRCm38) |
S829P |
probably benign |
Het |
| Pde6c |
T |
A |
19: 38,161,940 (GRCm38) |
F511Y |
probably damaging |
Het |
| Per3 |
G |
T |
4: 151,041,426 (GRCm38) |
H145Q |
probably damaging |
Het |
| Pglyrp1 |
C |
T |
7: 18,890,226 (GRCm38) |
R145W |
probably damaging |
Het |
| Piezo1 |
T |
C |
8: 122,482,645 (GRCm38) |
|
probably benign |
Het |
| Plb1 |
T |
C |
5: 32,286,847 (GRCm38) |
I312T |
probably benign |
Het |
| Plin3 |
T |
A |
17: 56,279,824 (GRCm38) |
T408S |
possibly damaging |
Het |
| Polr2a |
A |
T |
11: 69,743,946 (GRCm38) |
I636N |
probably damaging |
Het |
| Prex2 |
G |
T |
1: 11,162,366 (GRCm38) |
E886* |
probably null |
Het |
| Proca1 |
A |
T |
11: 78,205,021 (GRCm38) |
I73F |
probably damaging |
Het |
| Prpmp5 |
A |
T |
6: 132,314,698 (GRCm38) |
L11Q |
unknown |
Het |
| Ptpn6 |
A |
G |
6: 124,728,933 (GRCm38) |
S83P |
probably benign |
Het |
| Rtp1 |
G |
T |
16: 23,429,299 (GRCm38) |
V41L |
probably benign |
Het |
| Scn4a |
A |
G |
11: 106,327,533 (GRCm38) |
I1035T |
probably damaging |
Het |
| Sell |
A |
T |
1: 164,065,338 (GRCm38) |
Y41F |
probably damaging |
Het |
| Serping1 |
C |
T |
2: 84,771,449 (GRCm38) |
V226M |
probably damaging |
Het |
| Sf3b1 |
A |
T |
1: 54,998,188 (GRCm38) |
D856E |
possibly damaging |
Het |
| Sfmbt1 |
T |
A |
14: 30,802,567 (GRCm38) |
Y503N |
probably damaging |
Het |
| Slc16a1 |
T |
A |
3: 104,653,564 (GRCm38) |
V395D |
probably damaging |
Het |
| Slc22a7 |
A |
T |
17: 46,438,231 (GRCm38) |
D53E |
probably benign |
Het |
| Slc35b3 |
A |
G |
13: 38,960,611 (GRCm38) |
|
probably null |
Het |
| Slc6a1 |
T |
C |
6: 114,311,854 (GRCm38) |
M274T |
possibly damaging |
Het |
| Slco1a5 |
A |
G |
6: 142,242,063 (GRCm38) |
S517P |
probably benign |
Het |
| Smo |
A |
G |
6: 29,736,056 (GRCm38) |
R16G |
unknown |
Het |
| Srebf1 |
A |
G |
11: 60,203,486 (GRCm38) |
L601P |
probably damaging |
Het |
| Sspo |
A |
G |
6: 48,459,350 (GRCm38) |
I1086M |
probably benign |
Het |
| Tas2r106 |
A |
T |
6: 131,678,410 (GRCm38) |
N159K |
probably damaging |
Het |
| Thsd1 |
G |
A |
8: 22,252,318 (GRCm38) |
|
probably benign |
Het |
| Tmeff1 |
T |
C |
4: 48,658,938 (GRCm38) |
|
probably benign |
Het |
| Tmem140 |
G |
A |
6: 34,872,903 (GRCm38) |
C118Y |
possibly damaging |
Het |
| Tmem168 |
A |
G |
6: 13,583,071 (GRCm38) |
C220R |
probably benign |
Het |
| Tox2 |
A |
T |
2: 163,276,167 (GRCm38) |
N129Y |
probably damaging |
Het |
| Trappc12 |
C |
T |
12: 28,746,985 (GRCm38) |
E183K |
probably damaging |
Het |
| Unc50 |
A |
G |
1: 37,438,799 (GRCm38) |
Y254C |
probably damaging |
Het |
| Unk |
T |
G |
11: 116,059,081 (GRCm38) |
D691E |
probably benign |
Het |
| Uox |
T |
A |
3: 146,610,379 (GRCm38) |
V23D |
probably damaging |
Het |
| Vps13d |
A |
G |
4: 145,126,606 (GRCm38) |
C2313R |
probably benign |
Het |
| Zfp804b |
T |
A |
5: 6,769,283 (GRCm38) |
H1260L |
probably damaging |
Het |
| Zfyve26 |
A |
G |
12: 79,264,351 (GRCm38) |
L147P |
probably damaging |
Het |
| Zmynd10 |
A |
T |
9: 107,550,037 (GRCm38) |
Q288L |
probably benign |
Het |
| Zzef1 |
T |
A |
11: 72,848,714 (GRCm38) |
D662E |
probably damaging |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,906,045 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,859,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,862,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,886,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,852,431 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,906,920 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGTCAAGGCCTGCAGAAG -3'
(R):5'- GACAGATGTGCTCATAAGAAAGCTG -3'
Sequencing Primer
(F):5'- TAATTCTCCTAGGCCAGTGAGAC -3'
(R):5'- CTCATAAGAAAGCTGTAAGTGGCTG -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation