Incidental Mutation 'R1913:Plxnd1'
| ID |
214559 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnd1
|
| Ensembl Gene |
ENSMUSG00000030123 |
| Gene Name |
plexin D1 |
| Synonyms |
6230425C21Rik, b2b1863Clo, b2b553Clo |
| MMRRC Submission |
039931-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1913 (G1)
|
| Quality Score |
185 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
115931772-115971966 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 115954978 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Serine
at position 595
(A595S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000015511
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000015511]
|
| AlphaFold |
Q3UH93 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000015511
AA Change: A595S
PolyPhen 2
Score 0.504 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000015511
Gene: ENSMUSG00000030123
AA Change: A595S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
48 |
N/A |
INTRINSIC |
|
Sema
|
61 |
531 |
6.52e-90 |
SMART |
|
PSI
|
550 |
603 |
6.06e-12 |
SMART |
|
PSI
|
703 |
755 |
1.06e-2 |
SMART |
|
Blast:PSI
|
850 |
891 |
9e-20 |
BLAST |
|
IPT
|
892 |
981 |
4.43e-20 |
SMART |
|
IPT
|
982 |
1068 |
6.61e-19 |
SMART |
|
IPT
|
1070 |
1149 |
6.13e-14 |
SMART |
|
transmembrane domain
|
1271 |
1293 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1345 |
1888 |
5e-238 |
PFAM |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.6%
- 20x: 93.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display neonatal lethality, thin-walled atria, and vascular abnormalities including abnormal branchial arch artery development, cardiac outflow tract abnormalities, and reduced vascular smooth muscle around some vessels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca16 |
A |
T |
7: 120,140,463 (GRCm39) |
I1588F |
probably benign |
Het |
| Abcc2 |
A |
T |
19: 43,795,683 (GRCm39) |
T480S |
probably benign |
Het |
| Acnat1 |
A |
G |
4: 49,447,498 (GRCm39) |
I361T |
probably damaging |
Het |
| Adamts10 |
A |
T |
17: 33,768,529 (GRCm39) |
H869L |
probably benign |
Het |
| Agpat5 |
T |
C |
8: 18,929,629 (GRCm39) |
C253R |
probably benign |
Het |
| Agtrap |
T |
A |
4: 148,168,434 (GRCm39) |
H15L |
probably damaging |
Het |
| Ahnak |
T |
A |
19: 8,985,286 (GRCm39) |
V2190E |
probably damaging |
Het |
| Alx4 |
A |
G |
2: 93,505,732 (GRCm39) |
E278G |
probably damaging |
Het |
| Amz2 |
T |
C |
11: 109,319,697 (GRCm39) |
S28P |
probably damaging |
Het |
| Atr |
T |
A |
9: 95,748,786 (GRCm39) |
Y444N |
probably benign |
Het |
| Brdt |
T |
C |
5: 107,496,479 (GRCm39) |
I197T |
probably benign |
Het |
| Ccser1 |
G |
T |
6: 62,356,878 (GRCm39) |
S772I |
probably damaging |
Het |
| Cdh16 |
T |
C |
8: 105,343,100 (GRCm39) |
H657R |
probably benign |
Het |
| Ceacam5 |
A |
T |
7: 17,493,502 (GRCm39) |
K842* |
probably null |
Het |
| Cep120 |
G |
A |
18: 53,856,358 (GRCm39) |
T353I |
probably benign |
Het |
| Chrnb1 |
T |
C |
11: 69,684,410 (GRCm39) |
N164S |
possibly damaging |
Het |
| Cse1l |
T |
C |
2: 166,764,111 (GRCm39) |
F123L |
probably damaging |
Het |
| Cul7 |
T |
A |
17: 46,974,116 (GRCm39) |
L1467H |
probably damaging |
Het |
| Dcx |
G |
C |
X: 142,706,099 (GRCm39) |
L231V |
probably damaging |
Het |
| Dnah12 |
T |
C |
14: 26,514,221 (GRCm39) |
|
probably null |
Het |
| Dnah2 |
A |
T |
11: 69,355,756 (GRCm39) |
M2227K |
probably damaging |
Het |
| Dnajc30 |
G |
A |
5: 135,093,186 (GRCm39) |
A28T |
probably benign |
Het |
| Dnm1l |
T |
C |
16: 16,147,830 (GRCm39) |
T306A |
probably benign |
Het |
| Elapor2 |
T |
G |
5: 9,316,275 (GRCm39) |
L2R |
probably damaging |
Het |
| Enpp3 |
C |
A |
10: 24,652,669 (GRCm39) |
E763* |
probably null |
Het |
| Esyt3 |
T |
C |
9: 99,202,364 (GRCm39) |
S516G |
probably benign |
Het |
| Exoc3 |
T |
C |
13: 74,330,435 (GRCm39) |
Q498R |
probably damaging |
Het |
| Fbn2 |
T |
A |
18: 58,194,814 (GRCm39) |
N1449I |
probably damaging |
Het |
| Fgb |
T |
C |
3: 82,952,287 (GRCm39) |
D194G |
probably benign |
Het |
| Fgd3 |
T |
C |
13: 49,417,324 (GRCm39) |
D713G |
possibly damaging |
Het |
| Foxb1 |
T |
A |
9: 69,667,383 (GRCm39) |
Y49F |
possibly damaging |
Het |
| Fpr3 |
A |
G |
17: 18,191,670 (GRCm39) |
I314V |
probably damaging |
Het |
| Gfod1 |
A |
T |
13: 43,456,921 (GRCm39) |
I18N |
probably damaging |
Het |
| Gm5407 |
T |
C |
16: 49,117,283 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr89 |
A |
G |
3: 96,782,949 (GRCm39) |
F334L |
possibly damaging |
Het |
| Gucy2d |
G |
T |
7: 98,093,054 (GRCm39) |
V144F |
probably benign |
Het |
| H2-M10.5 |
C |
A |
17: 37,085,660 (GRCm39) |
P273H |
probably damaging |
Het |
| H2-T13 |
T |
A |
17: 36,391,908 (GRCm39) |
K237M |
probably damaging |
Het |
| Hcn2 |
A |
G |
10: 79,566,777 (GRCm39) |
M485V |
probably benign |
Het |
| Helz2 |
G |
T |
2: 180,875,543 (GRCm39) |
S1650R |
probably damaging |
Het |
| Ifnar2 |
T |
C |
16: 91,201,058 (GRCm39) |
V433A |
probably benign |
Het |
| Igsf21 |
T |
A |
4: 139,834,623 (GRCm39) |
Y83F |
probably benign |
Het |
| Kcnk18 |
A |
G |
19: 59,223,490 (GRCm39) |
I212V |
possibly damaging |
Het |
| Kcns2 |
T |
C |
15: 34,839,855 (GRCm39) |
I406T |
probably damaging |
Het |
| Krt42 |
C |
T |
11: 100,158,075 (GRCm39) |
V166M |
possibly damaging |
Het |
| Lama3 |
T |
C |
18: 12,628,336 (GRCm39) |
M1476T |
probably benign |
Het |
| Lcor |
A |
G |
19: 41,546,913 (GRCm39) |
R166G |
probably benign |
Het |
| Mapt |
C |
T |
11: 104,218,901 (GRCm39) |
P354L |
probably damaging |
Het |
| Mep1b |
A |
T |
18: 21,226,286 (GRCm39) |
I383F |
probably benign |
Het |
| Mpzl1 |
C |
A |
1: 165,429,374 (GRCm39) |
C222F |
probably benign |
Het |
| Mug2 |
T |
C |
6: 122,047,829 (GRCm39) |
L780P |
probably damaging |
Het |
| Naip2 |
C |
T |
13: 100,288,665 (GRCm39) |
|
probably null |
Het |
| Ndufab1 |
T |
C |
7: 121,695,914 (GRCm39) |
D41G |
probably benign |
Het |
| Ntn1 |
A |
G |
11: 68,104,011 (GRCm39) |
C546R |
probably damaging |
Het |
| Or2a5 |
T |
A |
6: 42,873,687 (GRCm39) |
F101I |
probably damaging |
Het |
| Pakap |
A |
G |
4: 57,892,963 (GRCm39) |
E880G |
probably damaging |
Het |
| Pde6b |
A |
G |
5: 108,575,056 (GRCm39) |
E639G |
probably benign |
Het |
| Phf10 |
T |
C |
17: 15,177,071 (GRCm39) |
T83A |
probably benign |
Het |
| Phkb |
T |
A |
8: 86,628,549 (GRCm39) |
I186N |
possibly damaging |
Het |
| Pkhd1 |
A |
G |
1: 20,636,980 (GRCm39) |
|
probably null |
Het |
| Ppara |
T |
A |
15: 85,685,300 (GRCm39) |
H416Q |
probably damaging |
Het |
| Prodh |
T |
A |
16: 17,898,891 (GRCm39) |
D188V |
probably damaging |
Het |
| Psmd14 |
A |
T |
2: 61,615,800 (GRCm39) |
K223M |
possibly damaging |
Het |
| Ptpn5 |
A |
G |
7: 46,728,616 (GRCm39) |
M528T |
possibly damaging |
Het |
| Rassf9 |
G |
A |
10: 102,380,800 (GRCm39) |
E59K |
probably benign |
Het |
| Rnf2 |
A |
T |
1: 151,351,936 (GRCm39) |
L140H |
probably damaging |
Het |
| Scai |
A |
G |
2: 38,970,093 (GRCm39) |
F557S |
probably damaging |
Het |
| Sdk2 |
A |
G |
11: 113,747,552 (GRCm39) |
S653P |
possibly damaging |
Het |
| Sec24c |
A |
G |
14: 20,739,179 (GRCm39) |
D534G |
probably benign |
Het |
| Semp2l2a |
T |
A |
8: 13,887,143 (GRCm39) |
Q316L |
probably benign |
Het |
| Septin4 |
T |
C |
11: 87,457,838 (GRCm39) |
S71P |
probably benign |
Het |
| Serinc1 |
A |
G |
10: 57,395,561 (GRCm39) |
V375A |
probably benign |
Het |
| Serpinb9f |
C |
T |
13: 33,509,829 (GRCm39) |
A7V |
probably damaging |
Het |
| Smco1 |
T |
C |
16: 32,092,700 (GRCm39) |
S124P |
probably damaging |
Het |
| Smim23 |
C |
A |
11: 32,774,441 (GRCm39) |
C26F |
possibly damaging |
Het |
| Sppl2c |
T |
A |
11: 104,078,715 (GRCm39) |
M505K |
probably benign |
Het |
| Sprr1b |
C |
A |
3: 92,344,775 (GRCm39) |
V34F |
possibly damaging |
Het |
| Sun1 |
G |
A |
5: 139,221,487 (GRCm39) |
|
probably null |
Het |
| Supt16 |
A |
G |
14: 52,415,592 (GRCm39) |
L381P |
possibly damaging |
Het |
| Syne2 |
A |
G |
12: 75,946,020 (GRCm39) |
D364G |
possibly damaging |
Het |
| Tax1bp1 |
G |
T |
6: 52,742,937 (GRCm39) |
V775F |
probably damaging |
Het |
| Tial1 |
T |
A |
7: 128,046,383 (GRCm39) |
I231F |
probably damaging |
Het |
| Tiam1 |
C |
A |
16: 89,595,582 (GRCm39) |
V1300L |
probably damaging |
Het |
| Tmem132e |
A |
G |
11: 82,334,243 (GRCm39) |
T585A |
probably damaging |
Het |
| Tnni3k |
C |
T |
3: 154,684,836 (GRCm39) |
A165T |
probably benign |
Het |
| Tomm40 |
A |
T |
7: 19,444,886 (GRCm39) |
I165N |
probably damaging |
Het |
| Tomt |
T |
C |
7: 101,550,454 (GRCm39) |
E104G |
probably damaging |
Het |
| Topaz1 |
T |
C |
9: 122,596,078 (GRCm39) |
S950P |
possibly damaging |
Het |
| Traf3ip2 |
C |
G |
10: 39,501,936 (GRCm39) |
P28R |
probably benign |
Het |
| Trim24 |
C |
T |
6: 37,934,750 (GRCm39) |
P822S |
probably damaging |
Het |
| Upf3a |
T |
G |
8: 13,842,108 (GRCm39) |
Y175D |
probably damaging |
Het |
| Vars2 |
G |
A |
17: 35,977,814 (GRCm39) |
P69S |
probably benign |
Het |
| Veph1 |
T |
C |
3: 66,151,976 (GRCm39) |
Y151C |
probably damaging |
Het |
| Vmn2r11 |
T |
A |
5: 109,202,654 (GRCm39) |
D141V |
probably benign |
Het |
| Vwa5b1 |
G |
A |
4: 138,319,331 (GRCm39) |
Q442* |
probably null |
Het |
| Wdr17 |
T |
A |
8: 55,140,761 (GRCm39) |
D197V |
probably damaging |
Het |
| Wdr70 |
G |
T |
15: 7,913,891 (GRCm39) |
T586N |
possibly damaging |
Het |
| Wfdc18 |
G |
A |
11: 83,600,754 (GRCm39) |
G52R |
probably benign |
Het |
| Zc3h6 |
T |
C |
2: 128,858,540 (GRCm39) |
I857T |
probably damaging |
Het |
| Zfp318 |
TGAAGAAGAAGAAGAAGAAGAAGAAGAAG |
TGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAG |
17: 46,723,440 (GRCm39) |
|
probably benign |
Het |
| Zfp318 |
GAAGAA |
GAAGAACAAGAA |
17: 46,723,450 (GRCm39) |
|
probably benign |
Het |
| Zfp647 |
C |
T |
15: 76,796,151 (GRCm39) |
V170I |
probably benign |
Het |
| Zfp871 |
T |
C |
17: 32,994,891 (GRCm39) |
N76D |
possibly damaging |
Het |
| Zpld2 |
A |
G |
4: 133,919,986 (GRCm39) |
|
probably null |
Het |
| Zwilch |
A |
G |
9: 64,068,234 (GRCm39) |
Y194H |
probably damaging |
Het |
|
| Other mutations in Plxnd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00764:Plxnd1
|
APN |
6 |
115,944,933 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01099:Plxnd1
|
APN |
6 |
115,946,906 (GRCm39) |
missense |
probably benign |
|
|
IGL01323:Plxnd1
|
APN |
6 |
115,943,760 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01382:Plxnd1
|
APN |
6 |
115,937,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Plxnd1
|
APN |
6 |
115,936,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02244:Plxnd1
|
APN |
6 |
115,955,218 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02272:Plxnd1
|
APN |
6 |
115,970,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02293:Plxnd1
|
APN |
6 |
115,940,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02465:Plxnd1
|
APN |
6 |
115,932,703 (GRCm39) |
makesense |
probably null |
|
|
IGL02873:Plxnd1
|
APN |
6 |
115,936,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03209:Plxnd1
|
APN |
6 |
115,939,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Hiss
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
murmer
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
mutter
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
rattle
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0357:Plxnd1
|
UTSW |
6 |
115,946,421 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0646:Plxnd1
|
UTSW |
6 |
115,935,660 (GRCm39) |
splice site |
probably benign |
|
|
R0648:Plxnd1
|
UTSW |
6 |
115,970,962 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0718:Plxnd1
|
UTSW |
6 |
115,943,599 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1116:Plxnd1
|
UTSW |
6 |
115,943,966 (GRCm39) |
splice site |
probably null |
|
|
R1292:Plxnd1
|
UTSW |
6 |
115,939,644 (GRCm39) |
unclassified |
probably benign |
|
|
R1715:Plxnd1
|
UTSW |
6 |
115,945,642 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1760:Plxnd1
|
UTSW |
6 |
115,944,740 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1799:Plxnd1
|
UTSW |
6 |
115,971,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1817:Plxnd1
|
UTSW |
6 |
115,957,562 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1848:Plxnd1
|
UTSW |
6 |
115,943,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1851:Plxnd1
|
UTSW |
6 |
115,940,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Plxnd1
|
UTSW |
6 |
115,946,402 (GRCm39) |
splice site |
probably null |
|
|
R1865:Plxnd1
|
UTSW |
6 |
115,946,402 (GRCm39) |
splice site |
probably null |
|
|
R1875:Plxnd1
|
UTSW |
6 |
115,955,045 (GRCm39) |
splice site |
probably null |
|
|
R1899:Plxnd1
|
UTSW |
6 |
115,946,324 (GRCm39) |
missense |
probably benign |
|
|
R1970:Plxnd1
|
UTSW |
6 |
115,939,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2007:Plxnd1
|
UTSW |
6 |
115,944,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2134:Plxnd1
|
UTSW |
6 |
115,934,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Plxnd1
|
UTSW |
6 |
115,939,725 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2230:Plxnd1
|
UTSW |
6 |
115,941,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2267:Plxnd1
|
UTSW |
6 |
115,939,704 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2427:Plxnd1
|
UTSW |
6 |
115,944,709 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4108:Plxnd1
|
UTSW |
6 |
115,936,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4233:Plxnd1
|
UTSW |
6 |
115,942,914 (GRCm39) |
missense |
probably benign |
0.30 |
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,056 (GRCm39) |
splice site |
probably null |
|
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,055 (GRCm39) |
splice site |
probably benign |
|
|
R4346:Plxnd1
|
UTSW |
6 |
115,954,941 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4439:Plxnd1
|
UTSW |
6 |
115,970,937 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4572:Plxnd1
|
UTSW |
6 |
115,932,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Plxnd1
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4599:Plxnd1
|
UTSW |
6 |
115,971,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4614:Plxnd1
|
UTSW |
6 |
115,949,486 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4700:Plxnd1
|
UTSW |
6 |
115,935,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Plxnd1
|
UTSW |
6 |
115,935,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4806:Plxnd1
|
UTSW |
6 |
115,937,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Plxnd1
|
UTSW |
6 |
115,932,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4977:Plxnd1
|
UTSW |
6 |
115,971,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5069:Plxnd1
|
UTSW |
6 |
115,942,862 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5155:Plxnd1
|
UTSW |
6 |
115,935,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5460:Plxnd1
|
UTSW |
6 |
115,934,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5729:Plxnd1
|
UTSW |
6 |
115,942,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Plxnd1
|
UTSW |
6 |
115,945,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5992:Plxnd1
|
UTSW |
6 |
115,944,748 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6129:Plxnd1
|
UTSW |
6 |
115,955,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Plxnd1
|
UTSW |
6 |
115,954,921 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6273:Plxnd1
|
UTSW |
6 |
115,955,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6310:Plxnd1
|
UTSW |
6 |
115,953,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6732:Plxnd1
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6857:Plxnd1
|
UTSW |
6 |
115,970,724 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7243:Plxnd1
|
UTSW |
6 |
115,949,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7282:Plxnd1
|
UTSW |
6 |
115,937,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7632:Plxnd1
|
UTSW |
6 |
115,953,600 (GRCm39) |
missense |
probably benign |
|
|
R7699:Plxnd1
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7915:Plxnd1
|
UTSW |
6 |
115,943,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8090:Plxnd1
|
UTSW |
6 |
115,933,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8382:Plxnd1
|
UTSW |
6 |
115,949,433 (GRCm39) |
missense |
probably benign |
|
|
R8507:Plxnd1
|
UTSW |
6 |
115,943,866 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8539:Plxnd1
|
UTSW |
6 |
115,939,768 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8548:Plxnd1
|
UTSW |
6 |
115,934,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8963:Plxnd1
|
UTSW |
6 |
115,949,506 (GRCm39) |
nonsense |
probably null |
|
|
R9119:Plxnd1
|
UTSW |
6 |
115,932,832 (GRCm39) |
splice site |
probably benign |
|
|
R9177:Plxnd1
|
UTSW |
6 |
115,943,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9182:Plxnd1
|
UTSW |
6 |
115,970,746 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9185:Plxnd1
|
UTSW |
6 |
115,934,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9226:Plxnd1
|
UTSW |
6 |
115,934,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9433:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9449:Plxnd1
|
UTSW |
6 |
115,932,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9451:Plxnd1
|
UTSW |
6 |
115,940,277 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9599:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9627:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9644:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9672:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
X0024:Plxnd1
|
UTSW |
6 |
115,940,271 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0026:Plxnd1
|
UTSW |
6 |
115,943,745 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
Z1088:Plxnd1
|
UTSW |
6 |
115,944,471 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGGTTGCATGGTCCTAACTG -3'
(R):5'- CTACTGTGGTTGGTGCACTC -3'
Sequencing Primer
(F):5'- CCTAACTGTTGACTAGGTCTTGCAAG -3'
(R):5'- TTGGTGCACTCTGGAGACC -3'
|
| Posted On |
2014-07-14 |
Incidental Mutation