Mutagenetix > Incidental Mutation

Incidental Mutation 'R1929:Dnah3'

215176

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

Dnahc3

MMRRC Submission

039947-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R1929 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

119521894-119694503 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 119574352 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 2136 (I2136F)

Ref Sequence

ENSEMBL: ENSMUSP00000146895 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000046993
AA Change: I2147F

PolyPhen 2 Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273
AA Change: I2147F

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000209154
AA Change: I2136F

PolyPhen 2 Score 0.096 (Sensitivity: 0.93; Specificity: 0.85)

Predicted Effect

probably benign
Transcript: ENSMUST00000213149

Meta Mutation Damage Score

0.1302

Coding Region Coverage

1x: 97.5%
3x: 96.9%
10x: 95.3%
20x: 92.4%

Validation Efficiency

98% (107/109)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 103 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adcy10	A	T	1: 165,337,866 (GRCm39)	E160V	probably damaging	Het
Amdhd2	T	C	17: 24,376,860 (GRCm39)		probably null	Het
Angel1	A	C	12: 86,749,093 (GRCm39)	L656V	probably damaging	Het
Ankrd12	G	A	17: 66,293,681 (GRCm39)	S584L	possibly damaging	Het
Apbb2	T	A	5: 66,464,958 (GRCm39)	N679Y	probably benign	Het
Arid3c	T	A	4: 41,724,744 (GRCm39)	I364F	probably damaging	Het
Bcan	T	A	3: 87,900,401 (GRCm39)	S611C	probably damaging	Het
Bnip3	T	G	7: 138,496,359 (GRCm39)		silent	Het
Btc	T	C	5: 91,510,260 (GRCm39)	Y111C	probably damaging	Het
Carnmt1	T	C	19: 18,680,734 (GRCm39)	L336P	probably damaging	Het
Ccdc83	C	T	7: 89,873,285 (GRCm39)	V357I	probably damaging	Het
Cd2bp2	T	C	7: 126,793,050 (GRCm39)	D324G	probably benign	Het
Cdc20b	A	G	13: 113,208,451 (GRCm39)	T216A	probably benign	Het
Cdk17	T	C	10: 93,064,540 (GRCm39)	Y270H	probably damaging	Het
Cenpv	T	C	11: 62,416,059 (GRCm39)	E230G	probably benign	Het
Chst11	T	C	10: 83,027,004 (GRCm39)	Y144H	probably damaging	Het
Cracr2a	T	A	6: 127,584,261 (GRCm39)	F107I	probably damaging	Het
Cyfip1	G	T	7: 55,549,705 (GRCm39)	R624L	probably null	Het
Cyp27b1	T	A	10: 126,884,181 (GRCm39)	V11D	probably damaging	Het
Ddc	T	C	11: 11,785,764 (GRCm39)	N308D	probably damaging	Het
Des	T	G	1: 75,340,137 (GRCm39)	M348R	probably damaging	Het
Dis3l	T	A	9: 64,238,165 (GRCm39)	D109V	probably damaging	Het
Dnah9	T	C	11: 65,867,224 (GRCm39)	S2785G	probably benign	Het
Dop1a	T	G	9: 86,376,471 (GRCm39)	V235G	probably damaging	Het
Dtx3l	A	T	16: 35,754,059 (GRCm39)	D182E	possibly damaging	Het
Efcab6	A	G	15: 83,777,163 (GRCm39)		probably benign	Het
Elac2	T	A	11: 64,870,015 (GRCm39)	S27T	probably benign	Het
Emsy	T	G	7: 98,275,830 (GRCm39)	K352N	probably damaging	Het
Erbb4	T	C	1: 68,238,047 (GRCm39)	N814S	probably damaging	Het
Fgd6	T	C	10: 93,880,868 (GRCm39)	V574A	probably benign	Het
Filip1	T	C	9: 79,727,212 (GRCm39)	E469G	probably damaging	Het
Fmo1	A	T	1: 162,661,424 (GRCm39)	D286E	probably damaging	Het
Fmo4	A	T	1: 162,626,616 (GRCm39)	I310N	possibly damaging	Het
Focad	A	G	4: 88,260,449 (GRCm39)	N902D	unknown	Het
Focad	A	G	4: 88,315,416 (GRCm39)	S1525G	probably benign	Het
Fras1	T	C	5: 96,815,296 (GRCm39)	W1338R	probably benign	Het
Fry	A	G	5: 150,324,389 (GRCm39)	I1151V	probably null	Het
Garin5b	T	A	7: 4,761,186 (GRCm39)	T509S	probably benign	Het
Gm10076	T	G	14: 105,919,304 (GRCm39)		noncoding transcript	Het
Gm5698	T	G	1: 31,017,042 (GRCm39)	D3A	probably damaging	Het
Gngt2	C	T	11: 95,735,972 (GRCm39)		probably benign	Het
Gsdma	T	C	11: 98,562,193 (GRCm39)		probably null	Het
Gtf2h3	A	T	5: 124,740,262 (GRCm39)		probably benign	Het
Hkdc1	T	C	10: 62,253,677 (GRCm39)	T35A	probably benign	Het
Irs1	T	C	1: 82,266,180 (GRCm39)	S679G	probably benign	Het
Itpr1	T	A	6: 108,470,716 (GRCm39)	C2214S	probably damaging	Het
Kcnh8	GAGACCAACGAGCAGCTGATGCTTCAGA	GAGA	17: 53,032,934 (GRCm39)	74	probably benign	Het
Kcnk16	A	G	14: 20,315,347 (GRCm39)	V72A	probably damaging	Het
Lipa	T	A	19: 34,488,290 (GRCm39)	R119*	probably null	Het
Matr3	T	A	18: 35,721,378 (GRCm39)		probably benign	Het
Med13l	T	G	5: 118,866,898 (GRCm39)	F651V	probably benign	Het
Mfsd11	T	C	11: 116,764,740 (GRCm39)	V388A	probably benign	Het
Mki67	C	T	7: 135,299,794 (GRCm39)	V1747I	possibly damaging	Het
Mms22l	T	C	4: 24,535,936 (GRCm39)		probably benign	Het
Msh5	A	G	17: 35,263,366 (GRCm39)	I154T	probably benign	Het
Myo5b	G	T	18: 74,866,996 (GRCm39)	L1382F	probably damaging	Het
Ncbp2	T	C	16: 31,775,769 (GRCm39)	Y138H	probably damaging	Het
Ndufv1	C	A	19: 4,058,347 (GRCm39)	R359L	probably benign	Het
Ntrk3	A	C	7: 78,166,471 (GRCm39)		probably null	Het
Or1e1c	T	A	11: 73,266,427 (GRCm39)	V287E	probably damaging	Het
Or4a15	A	G	2: 89,193,353 (GRCm39)	V140A	probably benign	Het
Or8b12i	T	A	9: 20,082,705 (GRCm39)	H54L	possibly damaging	Het
P4ha1	A	G	10: 59,206,859 (GRCm39)	E523G	probably damaging	Het
Per3	T	A	4: 151,103,342 (GRCm39)	Y530F	probably damaging	Het
Pes1	C	A	11: 3,919,524 (GRCm39)	L66I	probably damaging	Het
Pigr	G	A	1: 130,774,399 (GRCm39)		probably benign	Het
Pkd1l1	A	T	11: 8,786,197 (GRCm39)		probably benign	Het
Plch1	T	A	3: 63,651,956 (GRCm39)	K378N	probably damaging	Het
Plxnb1	T	C	9: 108,931,776 (GRCm39)		probably null	Het
Pramel22	G	A	4: 143,380,712 (GRCm39)	T437I	probably damaging	Het
Prkdc	A	G	16: 15,472,681 (GRCm39)		probably null	Het
Prrc1	G	T	18: 57,514,718 (GRCm39)	D312Y	probably damaging	Het
Psma5-ps	A	G	10: 85,149,595 (GRCm39)		noncoding transcript	Het
Rab3gap2	T	A	1: 185,015,739 (GRCm39)		probably null	Het
Rgs3	A	G	4: 62,620,384 (GRCm39)	I537V	probably damaging	Het
Rhobtb2	T	G	14: 70,033,893 (GRCm39)	D444A	probably damaging	Het
Rnf40	T	C	7: 127,190,956 (GRCm39)	S314P	probably damaging	Het
Rngtt	T	A	4: 33,500,302 (GRCm39)	C565*	probably null	Het
Samd3	A	G	10: 26,139,884 (GRCm39)		probably benign	Het
Sec61a2	A	G	2: 5,878,547 (GRCm39)		probably benign	Het
Serpina3m	G	A	12: 104,355,581 (GRCm39)	A83T	probably damaging	Het
Serpinb13	A	T	1: 106,926,756 (GRCm39)	I251L	possibly damaging	Het
Sez6	C	T	11: 77,863,758 (GRCm39)	T439I	probably damaging	Het
Shc1	G	A	3: 89,330,849 (GRCm39)	G91S	probably damaging	Het
Slc26a2	A	G	18: 61,331,650 (GRCm39)	C594R	possibly damaging	Het
Specc1l	C	T	10: 75,081,438 (GRCm39)	S278F	probably damaging	Het
Spg11	C	T	2: 121,890,688 (GRCm39)	V2044M	probably damaging	Het
Stx18	T	A	5: 38,285,383 (GRCm39)		probably null	Het
Suclg2	T	C	6: 95,566,075 (GRCm39)		probably benign	Het
Tlr4	A	T	4: 66,757,681 (GRCm39)	H158L	probably damaging	Het
Tmem131	A	G	1: 36,851,352 (GRCm39)	V966A	possibly damaging	Het
Tram1l1	T	A	3: 124,115,635 (GRCm39)	I265N	probably damaging	Het
Trim58	T	A	11: 58,531,493 (GRCm39)	F67Y	possibly damaging	Het
Ttc19	A	G	11: 62,172,650 (GRCm39)	Q74R	probably benign	Het
Usp7	T	C	16: 8,516,333 (GRCm39)	S649G	probably benign	Het
Vmn2r16	A	G	5: 109,487,124 (GRCm39)	Y115C	possibly damaging	Het
Zfp444	T	C	7: 6,192,554 (GRCm39)	C191R	probably damaging	Het
Zfp451	A	G	1: 33,821,274 (GRCm39)	F151L	probably damaging	Het
Zfp451	G	A	1: 33,822,937 (GRCm39)	P99S	probably benign	Het
Zfp729b	A	T	13: 67,740,352 (GRCm39)	C648S	probably damaging	Het
Zfp799	A	G	17: 33,040,777 (GRCm39)	Y58H	probably damaging	Het
Zfp804b	A	G	5: 6,819,748 (GRCm39)	V1069A	probably benign	Het
Zfp938	C	T	10: 82,061,381 (GRCm39)	G413D	probably damaging	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,538,128 (GRCm39)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,550,820 (GRCm39)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	119,622,164 (GRCm39)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,525,787 (GRCm39)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,566,943 (GRCm39)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,564,753 (GRCm39)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,542,798 (GRCm39)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,550,874 (GRCm39)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,550,437 (GRCm39)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	119,628,277 (GRCm39)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,550,494 (GRCm39)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,566,802 (GRCm39)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,550,215 (GRCm39)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,565,470 (GRCm39)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,538,137 (GRCm39)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,536,246 (GRCm39)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,564,720 (GRCm39)	missense	probably benign
IGL03404:Dnah3	APN	7	119,538,200 (GRCm39)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	119,618,924 (GRCm39)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	119,676,998 (GRCm39)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,521,953 (GRCm39)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	119,644,882 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,564,882 (GRCm39)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	possibly damaging	0.91
R0426:Dnah3	UTSW	7	119,542,795 (GRCm39)	missense	probably benign	0.11
R0525:Dnah3	UTSW	7	119,527,977 (GRCm39)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	119,671,110 (GRCm39)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	119,620,138 (GRCm39)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,567,128 (GRCm39)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	119,629,274 (GRCm39)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,551,962 (GRCm39)	splice site	probably benign
R0972:Dnah3	UTSW	7	119,634,563 (GRCm39)	splice site	probably null
R1066:Dnah3	UTSW	7	119,660,232 (GRCm39)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	119,677,668 (GRCm39)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,522,253 (GRCm39)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,538,227 (GRCm39)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	119,689,899 (GRCm39)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,551,202 (GRCm39)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	119,646,853 (GRCm39)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	119,670,181 (GRCm39)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	119,618,918 (GRCm39)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,525,672 (GRCm39)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,570,402 (GRCm39)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,527,963 (GRCm39)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	119,645,009 (GRCm39)	splice site	probably null
R1711:Dnah3	UTSW	7	119,677,794 (GRCm39)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	119,634,582 (GRCm39)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	119,677,625 (GRCm39)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,528,079 (GRCm39)	splice site	probably null
R1883:Dnah3	UTSW	7	119,677,142 (GRCm39)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	119,685,557 (GRCm39)	missense	probably benign	0.05
R1988:Dnah3	UTSW	7	119,567,182 (GRCm39)	missense	probably damaging	0.99
R1988:Dnah3	UTSW	7	119,566,793 (GRCm39)	missense	possibly damaging	0.92
R2010:Dnah3	UTSW	7	119,694,400 (GRCm39)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,550,465 (GRCm39)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	119,638,629 (GRCm39)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,551,132 (GRCm39)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,566,982 (GRCm39)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,551,236 (GRCm39)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,550,792 (GRCm39)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,574,352 (GRCm39)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	119,645,011 (GRCm39)	splice site	probably null
R2567:Dnah3	UTSW	7	119,551,920 (GRCm39)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,567,161 (GRCm39)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,550,722 (GRCm39)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,550,338 (GRCm39)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,550,333 (GRCm39)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	119,677,704 (GRCm39)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,566,879 (GRCm39)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,550,303 (GRCm39)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	119,685,943 (GRCm39)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	119,682,516 (GRCm39)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,522,061 (GRCm39)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	119,628,248 (GRCm39)	nonsense	probably null
R4478:Dnah3	UTSW	7	119,671,086 (GRCm39)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	119,608,554 (GRCm39)	missense	probably damaging	1.00
R4600:Dnah3	UTSW	7	119,689,169 (GRCm39)	missense	probably benign
R4649:Dnah3	UTSW	7	119,646,921 (GRCm39)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,549,874 (GRCm39)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	119,658,589 (GRCm39)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	119,677,169 (GRCm39)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	119,678,629 (GRCm39)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,567,047 (GRCm39)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	119,610,295 (GRCm39)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,550,904 (GRCm39)	nonsense	probably null
R4935:Dnah3	UTSW	7	119,615,700 (GRCm39)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,530,783 (GRCm39)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,555,424 (GRCm39)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,528,002 (GRCm39)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	119,671,128 (GRCm39)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,550,803 (GRCm39)	missense	probably damaging	1.00
R5056:Dnah3	UTSW	7	119,620,169 (GRCm39)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5069:Dnah3	UTSW	7	119,632,013 (GRCm39)	missense	probably benign
R5154:Dnah3	UTSW	7	119,551,642 (GRCm39)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	119,631,861 (GRCm39)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	119,620,234 (GRCm39)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,542,871 (GRCm39)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,524,126 (GRCm39)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	119,689,299 (GRCm39)	missense	probably benign	0.02
R5564:Dnah3	UTSW	7	119,570,689 (GRCm39)	critical splice donor site	probably null
R5594:Dnah3	UTSW	7	119,570,844 (GRCm39)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,538,288 (GRCm39)	splice site	probably null
R5673:Dnah3	UTSW	7	119,550,812 (GRCm39)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	119,677,074 (GRCm39)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	119,658,421 (GRCm39)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,577,445 (GRCm39)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	119,689,175 (GRCm39)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,542,822 (GRCm39)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,530,696 (GRCm39)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	119,638,585 (GRCm39)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,538,056 (GRCm39)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,550,244 (GRCm39)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,574,331 (GRCm39)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	119,668,927 (GRCm39)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	119,677,724 (GRCm39)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	119,615,749 (GRCm39)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,522,103 (GRCm39)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	119,672,764 (GRCm39)	missense	probably benign
R6004:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	119,670,870 (GRCm39)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,566,745 (GRCm39)	missense	probably damaging	0.99
R6056:Dnah3	UTSW	7	119,629,254 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah3	UTSW	7	119,685,469 (GRCm39)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,564,711 (GRCm39)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	119,608,607 (GRCm39)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	119,653,856 (GRCm39)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,522,191 (GRCm39)	splice site	probably null
R6447:Dnah3	UTSW	7	119,522,277 (GRCm39)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	119,660,179 (GRCm39)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	119,670,172 (GRCm39)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,522,197 (GRCm39)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,570,950 (GRCm39)	missense	probably benign
R6882:Dnah3	UTSW	7	119,570,407 (GRCm39)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	119,653,824 (GRCm39)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	119,631,977 (GRCm39)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	119,629,233 (GRCm39)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,570,312 (GRCm39)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,521,965 (GRCm39)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	119,670,746 (GRCm39)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	119,631,893 (GRCm39)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,542,856 (GRCm39)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,580,567 (GRCm39)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	119,629,208 (GRCm39)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	119,628,239 (GRCm39)	missense	probably benign
R7375:Dnah3	UTSW	7	119,550,900 (GRCm39)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	119,660,183 (GRCm39)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,565,474 (GRCm39)	missense
R7431:Dnah3	UTSW	7	119,650,967 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	119,660,135 (GRCm39)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	119,672,815 (GRCm39)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,570,817 (GRCm39)	missense	probably benign
R7618:Dnah3	UTSW	7	119,577,601 (GRCm39)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,566,657 (GRCm39)	missense
R7728:Dnah3	UTSW	7	119,538,051 (GRCm39)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,570,438 (GRCm39)	splice site	probably null
R7757:Dnah3	UTSW	7	119,670,793 (GRCm39)	missense	probably benign
R7774:Dnah3	UTSW	7	119,550,975 (GRCm39)	nonsense	probably null
R7804:Dnah3	UTSW	7	119,610,235 (GRCm39)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,551,841 (GRCm39)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,550,927 (GRCm39)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,566,775 (GRCm39)	missense
R7903:Dnah3	UTSW	7	119,641,351 (GRCm39)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,550,494 (GRCm39)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	119,677,012 (GRCm39)	missense	probably benign
R8142:Dnah3	UTSW	7	119,660,189 (GRCm39)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,566,837 (GRCm39)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,525,636 (GRCm39)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,550,375 (GRCm39)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	119,671,104 (GRCm39)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,551,728 (GRCm39)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	119,610,253 (GRCm39)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,551,431 (GRCm39)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,536,253 (GRCm39)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,550,591 (GRCm39)	missense	probably damaging	1.00
R8885:Dnah3	UTSW	7	119,561,375 (GRCm39)	missense
R8912:Dnah3	UTSW	7	119,689,869 (GRCm39)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,549,881 (GRCm39)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,536,294 (GRCm39)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,551,272 (GRCm39)	missense	probably benign
R9053:Dnah3	UTSW	7	119,618,987 (GRCm39)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	119,684,368 (GRCm39)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	119,684,351 (GRCm39)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,566,859 (GRCm39)	missense
R9383:Dnah3	UTSW	7	119,646,819 (GRCm39)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	119,628,205 (GRCm39)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,551,473 (GRCm39)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,551,523 (GRCm39)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	119,644,912 (GRCm39)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	119,650,951 (GRCm39)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	119,610,114 (GRCm39)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	119,670,236 (GRCm39)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,561,356 (GRCm39)	missense
R9633:Dnah3	UTSW	7	119,550,216 (GRCm39)	missense	probably benign
R9654:Dnah3	UTSW	7	119,641,396 (GRCm39)	nonsense	probably null
R9665:Dnah3	UTSW	7	119,644,981 (GRCm39)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	119,677,611 (GRCm39)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,574,299 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	119,610,096 (GRCm39)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	119,685,520 (GRCm39)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,567,026 (GRCm39)	missense
Z1177:Dnah3	UTSW	7	119,607,085 (GRCm39)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,567,124 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- ACATGAAGTCTGGAGCTAACCC -3'
(R):5'- TTGACCCCTGTAAAACCAAAGG -3'

Sequencing Primer
(F):5'- GTCTGGAGCTAACCCAAACCTTAG -3'
(R):5'- GGATCCCATAGACTCAGTGTG -3'

Posted On

2014-07-14