Mutagenetix > Incidental Mutation

Incidental Mutation 'R1932:Polq'

215513

Institutional Source

Beutler Lab

Gene Symbol

Polq

Ensembl Gene

ENSMUSG00000034206

Gene Name

polymerase (DNA directed), theta

Synonyms

A430110D14Rik

MMRRC Submission

039950-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.382) question?

Stock #

R1932 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

37011786-37095417 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 37062304 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Glutamine at position 1610 (R1610Q)

Ref Sequence

ENSEMBL: ENSMUSP00000059757 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000054034] [ENSMUST00000071452] [ENSMUST00000182946] [ENSMUST00000183112]

AlphaFold

Q8CGS6

Predicted Effect

possibly damaging
Transcript: ENSMUST00000054034
AA Change: R1610Q

PolyPhen 2 Score 0.917 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000059757
Gene: ENSMUSG00000034206
AA Change: R1610Q

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
DEXDc	87	298	4.09e-18	SMART
HELICc	398	484	4.02e-17	SMART
Blast:DEXDc	485	550	2e-25	BLAST
low complexity region	609	626	N/A	INTRINSIC
PDB:2ZJA\|A	712	826	5e-9	PDB
low complexity region	845	852	N/A	INTRINSIC
low complexity region	898	911	N/A	INTRINSIC
low complexity region	1126	1149	N/A	INTRINSIC
low complexity region	1813	1822	N/A	INTRINSIC
POLAc	2265	2504	3.3e-101	SMART
low complexity region	2521	2531	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000071452
AA Change: R1331Q

PolyPhen 2 Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000071396
Gene: ENSMUSG00000034206
AA Change: R1331Q

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
Pfam:DEAD	92	216	5.9e-12	PFAM
low complexity region	330	347	N/A	INTRINSIC
PDB:2ZJA\|A	433	547	5e-9	PDB
low complexity region	566	573	N/A	INTRINSIC
low complexity region	619	632	N/A	INTRINSIC
low complexity region	847	870	N/A	INTRINSIC
low complexity region	1534	1543	N/A	INTRINSIC
POLAc	1986	2225	3.3e-101	SMART
low complexity region	2242	2252	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000182622

Predicted Effect

probably benign
Transcript: ENSMUST00000182946

SMART Domains

Protein: ENSMUSP00000138685
Gene: ENSMUSG00000034206

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
Pfam:DEAD	92	164	1.3e-9	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000183112

SMART Domains

Protein: ENSMUSP00000138648
Gene: ENSMUSG00000034206

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
Pfam:DEAD	92	164	1.3e-9	PFAM

Coding Region Coverage

1x: 97.5%
3x: 97.0%
10x: 95.6%
20x: 93.3%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Animals carrying a homozygous mutation at this locus display elevated levels of chromosomal damage. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcg4	T	A	9: 44,279,394 (GRCm38)	Q278H	probably benign	Het
Ace3	T	C	11: 106,004,610 (GRCm38)		probably null	Het
Aco1	T	C	4: 40,176,499 (GRCm38)	V221A	probably damaging	Het
Adamts20	T	A	15: 94,404,010 (GRCm38)	H27L	probably benign	Het
Adamts8	A	G	9: 30,956,512 (GRCm38)	D544G	probably benign	Het
Angptl4	C	A	17: 33,781,275 (GRCm38)	E40*	probably null	Het
Arsi	G	A	18: 60,916,651 (GRCm38)	G202E	probably benign	Het
Atf7ip2	T	A	16: 10,241,703 (GRCm38)	I369N	possibly damaging	Het
Atp6ap1l	T	A	13: 90,883,687 (GRCm38)	Y292F	probably damaging	Het
Atp6v1b2	A	T	8: 69,102,807 (GRCm38)	K217*	probably null	Het
Bid	C	T	6: 120,897,255 (GRCm38)	A110T	possibly damaging	Het
Blvra	T	A	2: 127,095,148 (GRCm38)	W174R	probably damaging	Het
Catsperg1	C	T	7: 29,198,143 (GRCm38)	G239R	probably damaging	Het
Ccdc157	G	T	11: 4,146,549 (GRCm38)	A400D	probably damaging	Het
Chd2	G	T	7: 73,454,445 (GRCm38)	P1298T	probably damaging	Het
CK137956	G	A	4: 127,946,858 (GRCm38)	L352F	possibly damaging	Het
Col22a1	G	A	15: 71,870,140 (GRCm38)	P503S	unknown	Het
Cox15	C	T	19: 43,746,785 (GRCm38)	R181H	probably benign	Het
Crem	C	T	18: 3,299,284 (GRCm38)	G47R	probably benign	Het
Crygs	T	A	16: 22,806,554 (GRCm38)	T46S	probably benign	Het
Cts8	T	A	13: 61,253,615 (GRCm38)	H62L	probably damaging	Het
Cyp4a32	T	A	4: 115,611,277 (GRCm38)	F319I	possibly damaging	Het
Dchs1	T	C	7: 105,765,902 (GRCm38)	S692G	probably damaging	Het
Ddx23	G	A	15: 98,650,718 (GRCm38)	R370W	possibly damaging	Het
Defa29	A	T	8: 21,326,849 (GRCm38)	S43T	probably damaging	Het
Dnajc14	A	G	10: 128,816,792 (GRCm38)	D573G	probably damaging	Het
Drd5	A	G	5: 38,319,976 (GRCm38)	Y104C	probably benign	Het
Efcab7	C	T	4: 99,911,018 (GRCm38)	P102L	probably damaging	Het
Efhc1	A	G	1: 20,967,400 (GRCm38)	Y267C	probably damaging	Het
Eif2ak4	T	C	2: 118,448,486 (GRCm38)	Y243H	probably damaging	Het
Gfm2	T	A	13: 97,141,967 (GRCm38)	I7N	probably damaging	Het
Gmds	A	G	13: 32,127,997 (GRCm38)	F150L	possibly damaging	Het
Gp2	T	C	7: 119,454,232 (GRCm38)	T169A	possibly damaging	Het
Grb14	A	G	2: 64,912,802 (GRCm38)	F508L	probably damaging	Het
Hdac5	T	A	11: 102,195,872 (GRCm38)		probably benign	Het
Heatr1	T	A	13: 12,435,185 (GRCm38)	M620K	probably damaging	Het
Herc3	A	G	6: 58,876,793 (GRCm38)	E608G	probably damaging	Het
Hoxb4	T	C	11: 96,320,041 (GRCm38)	Y156H	probably damaging	Het
Ifi205	T	A	1: 174,028,414 (GRCm38)	I17F	possibly damaging	Het
Il2rb	A	T	15: 78,491,777 (GRCm38)	S25T	possibly damaging	Het
Kansl1	T	C	11: 104,335,097 (GRCm38)	T998A	probably damaging	Het
Kcna6	G	T	6: 126,738,488 (GRCm38)	H479Q	probably benign	Het
Kif2a	T	C	13: 106,978,091 (GRCm38)	K350R	probably benign	Het
Lct	G	T	1: 128,294,161 (GRCm38)	A1547E	probably damaging	Het
Lhx9	T	A	1: 138,842,009 (GRCm38)		probably benign	Het
Lingo1	T	A	9: 56,619,650 (GRCm38)	I552F	possibly damaging	Het
Lrp4	G	A	2: 91,497,355 (GRCm38)	W1516*	probably null	Het
Lrp5	C	T	19: 3,610,131 (GRCm38)	V978I	probably benign	Het
Ltbp1	T	A	17: 75,313,034 (GRCm38)	D719E	probably benign	Het
Ltbp4	A	G	7: 27,307,766 (GRCm38)		probably null	Het
Macf1	A	G	4: 123,452,037 (GRCm38)	I1326T	probably damaging	Het
Manba	T	C	3: 135,544,740 (GRCm38)	F376S	probably benign	Het
Mink1	T	C	11: 70,608,428 (GRCm38)		probably null	Het
Nfatc2ip	C	T	7: 126,384,992 (GRCm38)	V410I	probably damaging	Het
Nlrp1b	A	T	11: 71,182,138 (GRCm38)	I293N	probably damaging	Het
Olfr432	T	C	1: 174,050,678 (GRCm38)	Y102H	probably damaging	Het
Otol1	A	C	3: 70,028,104 (GRCm38)	E476D	probably benign	Het
Pcdhb4	C	T	18: 37,309,541 (GRCm38)	P635S	probably benign	Het
Pfkfb4	T	A	9: 108,999,169 (GRCm38)	F91I	probably damaging	Het
Polr3c	A	T	3: 96,719,298 (GRCm38)	L270H	probably damaging	Het
Ppp1r15b	C	T	1: 133,131,625 (GRCm38)		probably benign	Het
Prkca	T	G	11: 108,192,149 (GRCm38)	D90A	probably benign	Het
Sall3	T	C	18: 80,969,753 (GRCm38)	D1156G	probably benign	Het
Scn7a	A	T	2: 66,676,102 (GRCm38)	L1481H	probably damaging	Het
Selenon	A	T	4: 134,544,618 (GRCm38)	I292N	probably damaging	Het
Sema6d	T	A	2: 124,659,886 (GRCm38)		probably null	Het
Sgpp1	G	T	12: 75,716,179 (GRCm38)	Y409*	probably null	Het
Sh3pxd2a	A	G	19: 47,267,508 (GRCm38)	S924P	probably benign	Het
Slc25a13	A	G	6: 6,042,264 (GRCm38)	V638A	probably benign	Het
Snhg11	T	C	2: 158,376,826 (GRCm38)		probably benign	Het
Sorbs2	A	G	8: 45,796,352 (GRCm38)	Q800R	probably benign	Het
Srf	C	A	17: 46,549,986 (GRCm38)	G401C	probably damaging	Het
Stradb	A	C	1: 58,991,105 (GRCm38)	N173H	probably benign	Het
Swap70	C	T	7: 110,279,263 (GRCm38)	A480V	possibly damaging	Het
Sycp2	A	G	2: 178,381,957 (GRCm38)	V422A	probably damaging	Het
Taf4	G	A	2: 179,932,029 (GRCm38)	T682M	probably damaging	Het
Tet3	T	C	6: 83,404,379 (GRCm38)	N269S	possibly damaging	Het
Thap12	A	T	7: 98,716,838 (GRCm38)	I738F	possibly damaging	Het
Tiam2	C	T	17: 3,514,725 (GRCm38)	R1413C	possibly damaging	Het
Tmem229a	A	T	6: 24,955,011 (GRCm38)	F248Y	probably damaging	Het
Tmprss7	G	A	16: 45,684,593 (GRCm38)	Q145*	probably null	Het
Tnc	A	T	4: 63,993,025 (GRCm38)		probably null	Het
Tonsl	A	T	15: 76,624,597 (GRCm38)	Y21N	probably damaging	Het
Tpr	A	G	1: 150,421,663 (GRCm38)	D1009G	probably benign	Het
Trpm2	G	A	10: 77,941,158 (GRCm38)	A435V	probably damaging	Het
Ubr3	T	A	2: 69,953,476 (GRCm38)		probably null	Het
Vcan	T	C	13: 89,705,534 (GRCm38)	N436D	possibly damaging	Het
Vmn2r104	T	A	17: 20,040,769 (GRCm38)	Y464F	probably damaging	Het
Vmn2r44	T	A	7: 8,367,982 (GRCm38)	R688S	probably benign	Het
Wdr74	G	T	19: 8,737,947 (GRCm38)	V157L	probably benign	Het
Wnt7a	T	A	6: 91,394,548 (GRCm38)	D144V	probably benign	Het
Zfp106	C	T	2: 120,531,681 (GRCm38)	A986T	possibly damaging	Het

Other mutations in Polq

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00336:Polq	APN	16	37,065,247 (GRCm38)	splice site	probably benign
IGL00539:Polq	APN	16	37,060,569 (GRCm38)	missense	probably damaging	0.98
IGL00960:Polq	APN	16	37,060,512 (GRCm38)	missense	probably damaging	0.96
IGL01100:Polq	APN	16	37,061,112 (GRCm38)	missense	probably benign
IGL01112:Polq	APN	16	37,017,309 (GRCm38)	missense	probably damaging	1.00
IGL01138:Polq	APN	16	37,045,869 (GRCm38)	missense	possibly damaging	0.94
IGL01432:Polq	APN	16	37,071,822 (GRCm38)	splice site	probably benign
IGL01522:Polq	APN	16	37,027,903 (GRCm38)	missense	probably damaging	1.00
IGL01565:Polq	APN	16	37,013,113 (GRCm38)	missense	probably benign	0.00
IGL01592:Polq	APN	16	37,034,850 (GRCm38)	missense	probably benign	0.01
IGL01690:Polq	APN	16	37,062,838 (GRCm38)	missense	probably damaging	0.97
IGL01943:Polq	APN	16	37,061,443 (GRCm38)	missense	possibly damaging	0.47
IGL02531:Polq	APN	16	37,062,374 (GRCm38)	missense	possibly damaging	0.75
IGL02553:Polq	APN	16	37,041,768 (GRCm38)	missense	probably damaging	1.00
IGL02623:Polq	APN	16	37,060,375 (GRCm38)	missense	probably benign	0.04
IGL02692:Polq	APN	16	37,060,627 (GRCm38)	missense	probably damaging	1.00
IGL02717:Polq	APN	16	37,022,740 (GRCm38)	missense	probably damaging	1.00
IGL02937:Polq	APN	16	37,013,109 (GRCm38)	missense	probably benign	0.14
IGL02959:Polq	APN	16	37,086,566 (GRCm38)	missense	probably damaging	1.00
IGL03086:Polq	APN	16	37,091,049 (GRCm38)	missense	probably benign	0.02
IGL03141:Polq	APN	16	37,017,358 (GRCm38)	splice site	probably benign
IGL03302:Polq	APN	16	37,071,772 (GRCm38)	missense	probably damaging	1.00
IGL03393:Polq	APN	16	37,044,794 (GRCm38)	missense	probably damaging	1.00
R0013_Polq_667	UTSW	16	37,061,839 (GRCm38)	missense	possibly damaging	0.56
R4238_Polq_233	UTSW	16	37,013,181 (GRCm38)	missense	probably damaging	1.00
R4280_polq_867	UTSW	16	37,082,057 (GRCm38)	missense	probably damaging	1.00
G1Funyon:Polq	UTSW	16	37,061,819 (GRCm38)	missense	probably damaging	1.00
PIT4403001:Polq	UTSW	16	37,060,587 (GRCm38)	missense	probably benign	0.00
R0013:Polq	UTSW	16	37,061,839 (GRCm38)	missense	possibly damaging	0.56
R0082:Polq	UTSW	16	37,017,257 (GRCm38)	missense	probably benign	0.01
R0212:Polq	UTSW	16	37,066,854 (GRCm38)	missense	probably damaging	0.99
R0387:Polq	UTSW	16	37,089,317 (GRCm38)	missense	probably damaging	1.00
R0387:Polq	UTSW	16	37,029,430 (GRCm38)	missense	probably damaging	1.00
R0427:Polq	UTSW	16	37,061,993 (GRCm38)	nonsense	probably null
R0454:Polq	UTSW	16	37,034,890 (GRCm38)	missense	probably damaging	0.98
R0513:Polq	UTSW	16	37,094,502 (GRCm38)	missense	probably damaging	1.00
R0622:Polq	UTSW	16	37,060,993 (GRCm38)	missense	probably benign	0.02
R0848:Polq	UTSW	16	37,062,130 (GRCm38)	missense	probably benign	0.08
R1142:Polq	UTSW	16	37,013,217 (GRCm38)	missense	probably damaging	0.98
R1218:Polq	UTSW	16	37,029,446 (GRCm38)	missense	possibly damaging	0.93
R1331:Polq	UTSW	16	37,041,747 (GRCm38)	missense	probably damaging	1.00
R1398:Polq	UTSW	16	37,062,495 (GRCm38)	missense	possibly damaging	0.87
R1424:Polq	UTSW	16	37,086,528 (GRCm38)	missense	probably damaging	1.00
R1644:Polq	UTSW	16	37,060,264 (GRCm38)	missense	probably damaging	0.96
R1777:Polq	UTSW	16	37,060,224 (GRCm38)	missense	possibly damaging	0.94
R1820:Polq	UTSW	16	37,029,418 (GRCm38)	missense	possibly damaging	0.48
R1854:Polq	UTSW	16	37,062,109 (GRCm38)	missense	probably benign	0.01
R1880:Polq	UTSW	16	37,086,592 (GRCm38)	missense	possibly damaging	0.90
R2008:Polq	UTSW	16	37,062,482 (GRCm38)	missense	probably damaging	0.96
R2014:Polq	UTSW	16	37,078,366 (GRCm38)	missense	probably damaging	1.00
R2026:Polq	UTSW	16	37,062,745 (GRCm38)	missense	possibly damaging	0.93
R2178:Polq	UTSW	16	37,062,829 (GRCm38)	missense	probably damaging	1.00
R2259:Polq	UTSW	16	37,062,097 (GRCm38)	missense	probably benign	0.03
R2266:Polq	UTSW	16	37,062,153 (GRCm38)	missense	possibly damaging	0.59
R2305:Polq	UTSW	16	37,062,337 (GRCm38)	missense	probably damaging	0.99
R2370:Polq	UTSW	16	37,073,939 (GRCm38)	missense	probably damaging	1.00
R2504:Polq	UTSW	16	37,011,942 (GRCm38)	missense	unknown
R2517:Polq	UTSW	16	37,089,325 (GRCm38)	missense	probably damaging	1.00
R2697:Polq	UTSW	16	37,042,153 (GRCm38)	missense	probably damaging	1.00
R2858:Polq	UTSW	16	37,062,753 (GRCm38)	missense	possibly damaging	0.88
R3436:Polq	UTSW	16	37,062,337 (GRCm38)	missense	probably damaging	0.99
R3437:Polq	UTSW	16	37,062,337 (GRCm38)	missense	probably damaging	0.99
R3699:Polq	UTSW	16	37,042,156 (GRCm38)	missense	probably damaging	1.00
R3838:Polq	UTSW	16	37,078,349 (GRCm38)	missense	probably damaging	1.00
R3875:Polq	UTSW	16	37,074,027 (GRCm38)	missense	probably damaging	0.99
R4050:Polq	UTSW	16	37,092,820 (GRCm38)	critical splice acceptor site	probably null
R4172:Polq	UTSW	16	37,060,758 (GRCm38)	missense	probably benign	0.02
R4238:Polq	UTSW	16	37,013,181 (GRCm38)	missense	probably damaging	1.00
R4240:Polq	UTSW	16	37,013,181 (GRCm38)	missense	probably damaging	1.00
R4280:Polq	UTSW	16	37,082,057 (GRCm38)	missense	probably damaging	1.00
R4296:Polq	UTSW	16	37,061,301 (GRCm38)	missense	possibly damaging	0.94
R4360:Polq	UTSW	16	37,060,339 (GRCm38)	missense	probably benign	0.00
R4373:Polq	UTSW	16	37,013,181 (GRCm38)	missense	probably damaging	1.00
R4375:Polq	UTSW	16	37,013,181 (GRCm38)	missense	probably damaging	1.00
R4376:Polq	UTSW	16	37,013,181 (GRCm38)	missense	probably damaging	1.00
R4509:Polq	UTSW	16	37,048,563 (GRCm38)	missense	probably damaging	1.00
R4510:Polq	UTSW	16	37,048,563 (GRCm38)	missense	probably damaging	1.00
R4511:Polq	UTSW	16	37,048,563 (GRCm38)	missense	probably damaging	1.00
R4543:Polq	UTSW	16	37,060,785 (GRCm38)	missense	probably benign	0.43
R4633:Polq	UTSW	16	37,048,542 (GRCm38)	missense	probably damaging	1.00
R4739:Polq	UTSW	16	37,041,747 (GRCm38)	missense	probably damaging	1.00
R4834:Polq	UTSW	16	37,027,814 (GRCm38)	missense	probably damaging	1.00
R4841:Polq	UTSW	16	37,048,783 (GRCm38)	critical splice donor site	probably null
R4842:Polq	UTSW	16	37,048,783 (GRCm38)	critical splice donor site	probably null
R4937:Polq	UTSW	16	37,027,912 (GRCm38)	missense	probably benign	0.01
R4955:Polq	UTSW	16	37,061,082 (GRCm38)	missense	probably benign	0.32
R4992:Polq	UTSW	16	37,061,162 (GRCm38)	missense	possibly damaging	0.59
R5008:Polq	UTSW	16	37,062,387 (GRCm38)	missense	probably benign
R5221:Polq	UTSW	16	37,042,178 (GRCm38)	missense	probably damaging	0.98
R5254:Polq	UTSW	16	37,089,319 (GRCm38)	missense	probably damaging	1.00
R5292:Polq	UTSW	16	37,061,383 (GRCm38)	missense	probably damaging	1.00
R5375:Polq	UTSW	16	37,082,784 (GRCm38)	missense	probably damaging	1.00
R5480:Polq	UTSW	16	37,013,290 (GRCm38)	splice site	probably benign
R5552:Polq	UTSW	16	37,094,510 (GRCm38)	missense	possibly damaging	0.93
R5591:Polq	UTSW	16	37,011,885 (GRCm38)	utr 5 prime	probably benign
R5653:Polq	UTSW	16	37,040,534 (GRCm38)	missense	probably damaging	1.00
R5708:Polq	UTSW	16	37,061,018 (GRCm38)	missense	probably damaging	0.98
R5754:Polq	UTSW	16	37,017,263 (GRCm38)	missense	probably benign
R5757:Polq	UTSW	16	37,086,681 (GRCm38)	missense	probably benign	0.01
R5764:Polq	UTSW	16	37,017,344 (GRCm38)	missense	probably damaging	0.97
R6019:Polq	UTSW	16	37,061,764 (GRCm38)	missense	probably damaging	1.00
R6170:Polq	UTSW	16	37,045,812 (GRCm38)	missense	possibly damaging	0.82
R6177:Polq	UTSW	16	37,071,709 (GRCm38)	missense	probably damaging	0.98
R6307:Polq	UTSW	16	37,017,356 (GRCm38)	critical splice donor site	probably null
R6499:Polq	UTSW	16	37,060,827 (GRCm38)	missense	probably benign	0.03
R6520:Polq	UTSW	16	37,060,377 (GRCm38)	missense	possibly damaging	0.88
R6598:Polq	UTSW	16	37,061,631 (GRCm38)	missense	probably benign	0.39
R6694:Polq	UTSW	16	37,015,173 (GRCm38)	missense	probably null	0.99
R6788:Polq	UTSW	16	37,077,148 (GRCm38)	missense	probably damaging	1.00
R7104:Polq	UTSW	16	37,089,353 (GRCm38)	nonsense	probably null
R7159:Polq	UTSW	16	37,062,853 (GRCm38)	missense	possibly damaging	0.87
R7222:Polq	UTSW	16	37,086,633 (GRCm38)	nonsense	probably null
R7340:Polq	UTSW	16	37,060,926 (GRCm38)	missense	probably benign	0.00
R7361:Polq	UTSW	16	37,060,428 (GRCm38)	missense	probably benign	0.00
R7384:Polq	UTSW	16	37,029,418 (GRCm38)	missense	probably damaging	1.00
R7509:Polq	UTSW	16	37,060,344 (GRCm38)	missense	probably benign	0.00
R7509:Polq	UTSW	16	37,060,343 (GRCm38)	missense	probably benign
R7575:Polq	UTSW	16	37,091,134 (GRCm38)	missense	probably benign	0.00
R7785:Polq	UTSW	16	37,027,877 (GRCm38)	missense	probably damaging	1.00
R7787:Polq	UTSW	16	37,017,309 (GRCm38)	missense	probably damaging	1.00
R7891:Polq	UTSW	16	37,027,882 (GRCm38)	missense	probably damaging	1.00
R7898:Polq	UTSW	16	37,044,883 (GRCm38)	missense	probably damaging	0.98
R7917:Polq	UTSW	16	37,065,288 (GRCm38)	missense	probably benign	0.08
R7940:Polq	UTSW	16	37,060,642 (GRCm38)	missense	probably benign	0.27
R8028:Polq	UTSW	16	37,061,316 (GRCm38)	missense	possibly damaging	0.82
R8114:Polq	UTSW	16	37,042,215 (GRCm38)	missense	possibly damaging	0.94
R8144:Polq	UTSW	16	37,029,484 (GRCm38)	missense	probably benign	0.01
R8288:Polq	UTSW	16	37,027,910 (GRCm38)	missense	probably damaging	1.00
R8301:Polq	UTSW	16	37,061,819 (GRCm38)	missense	probably damaging	1.00
R8341:Polq	UTSW	16	37,071,771 (GRCm38)	missense	possibly damaging	0.96
R8348:Polq	UTSW	16	37,017,197 (GRCm38)	critical splice acceptor site	probably null
R8448:Polq	UTSW	16	37,017,197 (GRCm38)	critical splice acceptor site	probably null
R8815:Polq	UTSW	16	37,033,531 (GRCm38)	missense	probably damaging	1.00
R8843:Polq	UTSW	16	37,011,918 (GRCm38)	missense	unknown
R8878:Polq	UTSW	16	37,040,507 (GRCm38)	missense	probably benign	0.02
R9016:Polq	UTSW	16	37,022,797 (GRCm38)	missense	probably damaging	1.00
R9189:Polq	UTSW	16	37,044,903 (GRCm38)	missense	probably damaging	1.00
R9209:Polq	UTSW	16	37,048,649 (GRCm38)	missense	possibly damaging	0.94
R9352:Polq	UTSW	16	37,041,890 (GRCm38)	missense	probably damaging	0.98
R9398:Polq	UTSW	16	37,061,032 (GRCm38)	missense	probably benign	0.02
R9403:Polq	UTSW	16	37,061,853 (GRCm38)	missense	probably benign	0.00
R9489:Polq	UTSW	16	37,022,811 (GRCm38)	missense	probably benign	0.00
R9605:Polq	UTSW	16	37,022,811 (GRCm38)	missense	probably benign	0.00
R9664:Polq	UTSW	16	37,027,814 (GRCm38)	missense	probably damaging	0.98
R9801:Polq	UTSW	16	37,092,828 (GRCm38)	missense	probably damaging	1.00
X0060:Polq	UTSW	16	37,017,237 (GRCm38)	nonsense	probably null
Z1176:Polq	UTSW	16	37,042,257 (GRCm38)	critical splice donor site	probably null

Predicted Primers

PCR Primer
(F):5'- CAGTGATTCTGCAGTGCTGG -3'
(R):5'- ACTTTCTTTACGAGGCAAGGG -3'

Sequencing Primer
(F):5'- CTGGGTAATGAGTGTCCCCAAG -3'
(R):5'- ACTTTCTTTACGAGGCAAGGGAGATG -3'

Posted On

2014-07-14