Incidental Mutation 'R1964:Ddx60'
| ID |
217107 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| Synonyms |
|
| MMRRC Submission |
039977-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.199)
|
| Stock # |
R1964 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
61928087-62038244 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 61948869 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 260
(C260S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000122841
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
[ENSMUST00000154398]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070631
AA Change: C260S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
AA Change: C260S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093485
AA Change: C260S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
AA Change: C260S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154398
AA Change: C260S
PolyPhen 2
Score 0.097 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000122841
Gene: ENSMUSG00000037921
AA Change: C260S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
C |
T |
17: 8,992,492 (GRCm38) |
H158Y |
probably damaging |
Het |
| 1810009J06Rik |
T |
A |
6: 40,968,207 (GRCm38) |
C207S |
probably damaging |
Het |
| Aadac |
T |
A |
3: 60,037,338 (GRCm38) |
|
probably null |
Het |
| Abca6 |
T |
A |
11: 110,184,676 (GRCm38) |
I1330F |
probably damaging |
Het |
| Adar |
A |
T |
3: 89,745,895 (GRCm38) |
S263C |
probably benign |
Het |
| Adra2b |
T |
C |
2: 127,363,814 (GRCm38) |
Y84H |
probably damaging |
Het |
| Arnt2 |
A |
T |
7: 84,343,789 (GRCm38) |
V181E |
possibly damaging |
Het |
| Atg7 |
T |
C |
6: 114,706,230 (GRCm38) |
L418P |
probably damaging |
Het |
| Atp2c1 |
A |
G |
9: 105,446,123 (GRCm38) |
L181P |
probably damaging |
Het |
| Awat2 |
G |
A |
X: 100,404,559 (GRCm38) |
P148S |
probably damaging |
Het |
| Birc6 |
A |
G |
17: 74,634,885 (GRCm38) |
M2737V |
possibly damaging |
Het |
| Ccdc81 |
A |
G |
7: 89,886,153 (GRCm38) |
C292R |
probably benign |
Het |
| Cd14 |
T |
A |
18: 36,726,339 (GRCm38) |
E21V |
probably damaging |
Het |
| Cdc14b |
A |
C |
13: 64,215,537 (GRCm38) |
C303W |
probably damaging |
Het |
| Cdh23 |
T |
C |
10: 60,385,222 (GRCm38) |
I1248V |
probably benign |
Het |
| Ceacam1 |
T |
C |
7: 25,474,708 (GRCm38) |
D174G |
probably benign |
Het |
| Cgas |
T |
G |
9: 78,437,455 (GRCm38) |
Y228S |
probably damaging |
Het |
| Chd7 |
A |
G |
4: 8,865,978 (GRCm38) |
M717V |
probably damaging |
Het |
| Cib1 |
T |
C |
7: 80,232,372 (GRCm38) |
T20A |
possibly damaging |
Het |
| Clec4d |
A |
G |
6: 123,262,360 (GRCm38) |
K9R |
probably benign |
Het |
| Cntnap1 |
C |
A |
11: 101,178,024 (GRCm38) |
S131* |
probably null |
Het |
| Crybg1 |
T |
C |
10: 43,958,330 (GRCm38) |
K1581R |
probably damaging |
Het |
| Csf2 |
T |
G |
11: 54,248,458 (GRCm38) |
T100P |
probably benign |
Het |
| Csrp2 |
T |
A |
10: 110,932,033 (GRCm38) |
D26E |
probably benign |
Het |
| Cul1 |
T |
C |
6: 47,502,571 (GRCm38) |
V257A |
probably damaging |
Het |
| Cul4a |
G |
A |
8: 13,136,406 (GRCm38) |
M505I |
possibly damaging |
Het |
| Cul4a |
T |
C |
8: 13,136,854 (GRCm38) |
M530T |
probably benign |
Het |
| Dcp2 |
T |
C |
18: 44,395,971 (GRCm38) |
M51T |
possibly damaging |
Het |
| Dennd2c |
G |
A |
3: 103,166,491 (GRCm38) |
R851H |
probably damaging |
Het |
| Dnah11 |
T |
C |
12: 118,142,292 (GRCm38) |
E625G |
possibly damaging |
Het |
| Edem1 |
T |
C |
6: 108,844,947 (GRCm38) |
W322R |
probably benign |
Het |
| Egflam |
T |
C |
15: 7,247,105 (GRCm38) |
T527A |
probably damaging |
Het |
| Ephb1 |
T |
A |
9: 101,971,123 (GRCm38) |
M659L |
possibly damaging |
Het |
| Fbxl2 |
A |
G |
9: 113,989,169 (GRCm38) |
I203T |
probably benign |
Het |
| Gabbr1 |
G |
A |
17: 37,048,459 (GRCm38) |
G109R |
probably damaging |
Het |
| Gabra2 |
T |
C |
5: 71,014,450 (GRCm38) |
I148V |
possibly damaging |
Het |
| Golga1 |
A |
G |
2: 39,047,087 (GRCm38) |
V161A |
probably benign |
Het |
| Gps2 |
T |
G |
11: 69,916,420 (GRCm38) |
S301A |
probably benign |
Het |
| H2-D1 |
T |
C |
17: 35,263,619 (GRCm38) |
L105P |
probably benign |
Het |
| Igdcc4 |
T |
C |
9: 65,122,769 (GRCm38) |
V367A |
probably benign |
Het |
| Igkv4-69 |
T |
G |
6: 69,283,798 (GRCm38) |
Y115S |
probably benign |
Het |
| Itga5 |
A |
G |
15: 103,354,314 (GRCm38) |
L309P |
probably damaging |
Het |
| Itih1 |
A |
G |
14: 30,929,623 (GRCm38) |
Y871H |
probably damaging |
Het |
| Itpr2 |
T |
A |
6: 146,111,693 (GRCm38) |
N2662I |
probably damaging |
Het |
| Kctd19 |
T |
A |
8: 105,388,470 (GRCm38) |
E486D |
probably damaging |
Het |
| Kif5b |
C |
T |
18: 6,209,059 (GRCm38) |
R901Q |
possibly damaging |
Het |
| Kmt2a |
G |
A |
9: 44,820,644 (GRCm38) |
S2792F |
probably benign |
Het |
| Magi3 |
A |
G |
3: 104,020,402 (GRCm38) |
V1023A |
probably damaging |
Het |
| Mapk9 |
C |
A |
11: 49,854,333 (GRCm38) |
R25S |
probably null |
Het |
| Memo1 |
T |
C |
17: 74,245,008 (GRCm38) |
T98A |
possibly damaging |
Het |
| Mill2 |
A |
G |
7: 18,856,604 (GRCm38) |
K203R |
probably damaging |
Het |
| Mios |
T |
A |
6: 8,215,798 (GRCm38) |
H331Q |
probably damaging |
Het |
| Muc6 |
G |
T |
7: 141,640,062 (GRCm38) |
S1566* |
probably null |
Het |
| Muc6 |
A |
G |
7: 141,640,063 (GRCm38) |
|
probably benign |
Het |
| Napsa |
T |
C |
7: 44,581,685 (GRCm38) |
F113L |
probably benign |
Het |
| Or5ac16 |
T |
A |
16: 59,201,908 (GRCm38) |
I173F |
possibly damaging |
Het |
| Or9m1 |
A |
G |
2: 87,903,667 (GRCm38) |
V3A |
probably benign |
Het |
| Oscp1 |
T |
G |
4: 126,083,622 (GRCm38) |
V226G |
possibly damaging |
Het |
| Osgin2 |
G |
T |
4: 15,998,358 (GRCm38) |
S421R |
probably damaging |
Het |
| Pclaf |
A |
G |
9: 65,893,395 (GRCm38) |
N50D |
probably damaging |
Het |
| Pdgfc |
A |
T |
3: 81,174,985 (GRCm38) |
I162F |
probably benign |
Het |
| Plag1 |
T |
C |
4: 3,903,956 (GRCm38) |
T412A |
probably benign |
Het |
| Pogz |
A |
T |
3: 94,878,193 (GRCm38) |
T820S |
probably benign |
Het |
| Ptpn9 |
T |
A |
9: 57,059,912 (GRCm38) |
V473D |
probably damaging |
Het |
| Qdpr |
A |
T |
5: 45,439,318 (GRCm38) |
M66K |
possibly damaging |
Het |
| Qrich1 |
A |
G |
9: 108,534,422 (GRCm38) |
N382S |
possibly damaging |
Het |
| Rbbp8 |
T |
C |
18: 11,742,679 (GRCm38) |
V883A |
possibly damaging |
Het |
| Rgl1 |
T |
A |
1: 152,549,104 (GRCm38) |
I375F |
probably damaging |
Het |
| Rif1 |
C |
T |
2: 52,098,409 (GRCm38) |
T720I |
probably benign |
Het |
| Rilp |
A |
T |
11: 75,510,502 (GRCm38) |
Q95L |
probably benign |
Het |
| Rnf169 |
T |
A |
7: 99,925,525 (GRCm38) |
N621I |
probably damaging |
Het |
| Rps27a |
T |
C |
11: 29,547,229 (GRCm38) |
K27R |
probably null |
Het |
| Sar1a |
T |
C |
10: 61,685,168 (GRCm38) |
V54A |
probably benign |
Het |
| Sash1 |
T |
A |
10: 8,729,713 (GRCm38) |
H971L |
probably benign |
Het |
| Sdk2 |
G |
A |
11: 113,781,017 (GRCm38) |
Q2102* |
probably null |
Het |
| Serpina1e |
T |
A |
12: 103,951,207 (GRCm38) |
I68F |
probably damaging |
Het |
| Serpinb9e |
A |
C |
13: 33,253,491 (GRCm38) |
Q119P |
probably benign |
Het |
| Sh3tc2 |
A |
T |
18: 61,991,155 (GRCm38) |
K965* |
probably null |
Het |
| Slc16a1 |
A |
T |
3: 104,649,466 (GRCm38) |
S56C |
probably damaging |
Het |
| Slc26a11 |
T |
A |
11: 119,380,194 (GRCm38) |
L563Q |
possibly damaging |
Het |
| Smarca2 |
G |
T |
19: 26,672,724 (GRCm38) |
E24* |
probably null |
Het |
| Smgc |
G |
A |
15: 91,860,270 (GRCm38) |
G239D |
probably damaging |
Het |
| Sos2 |
A |
T |
12: 69,616,862 (GRCm38) |
M616K |
possibly damaging |
Het |
| Tet1 |
T |
A |
10: 62,812,947 (GRCm38) |
D1902V |
possibly damaging |
Het |
| Thap2 |
C |
T |
10: 115,384,247 (GRCm38) |
C10Y |
probably damaging |
Het |
| Tln2 |
T |
C |
9: 67,342,135 (GRCm38) |
D890G |
probably benign |
Het |
| Tor2a |
G |
A |
2: 32,758,704 (GRCm38) |
G62D |
probably damaging |
Het |
| Ubqln5 |
A |
T |
7: 104,128,888 (GRCm38) |
V243E |
possibly damaging |
Het |
| Utrn |
A |
T |
10: 12,684,437 (GRCm38) |
D1369E |
probably damaging |
Het |
| Vcan |
A |
G |
13: 89,692,742 (GRCm38) |
V1561A |
probably benign |
Het |
| Vmn1r70 |
T |
C |
7: 10,633,810 (GRCm38) |
F56S |
possibly damaging |
Het |
| Vmn2r25 |
A |
G |
6: 123,823,295 (GRCm38) |
L696S |
possibly damaging |
Het |
| Washc2 |
A |
G |
6: 116,208,987 (GRCm38) |
T53A |
probably damaging |
Het |
| Wnk1 |
T |
A |
6: 119,934,382 (GRCm38) |
T2417S |
possibly damaging |
Het |
| Zbtb49 |
A |
T |
5: 38,203,761 (GRCm38) |
C12* |
probably null |
Het |
| Zfp472 |
C |
A |
17: 32,977,874 (GRCm38) |
P308T |
possibly damaging |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
61,958,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
61,987,431 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
61,969,583 (GRCm38) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
61,942,514 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
61,982,526 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
61,963,740 (GRCm38) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
61,983,865 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,017,823 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,000,709 (GRCm38) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,017,247 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
61,975,832 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
61,958,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,024,951 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
61,942,436 (GRCm38) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
61,984,115 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
61,988,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
61,979,341 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
61,956,122 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
61,988,083 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,012,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
61,977,882 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
61,958,113 (GRCm38) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
61,972,254 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
61,942,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,033,493 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0325:Ddx60
|
UTSW |
8 |
61,983,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0367:Ddx60
|
UTSW |
8 |
62,017,749 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R0403:Ddx60
|
UTSW |
8 |
61,994,541 (GRCm38) |
splice site |
probably benign |
|
|
R0479:Ddx60
|
UTSW |
8 |
61,969,657 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,017,794 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
61,987,361 (GRCm38) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
61,942,544 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
61,958,159 (GRCm38) |
splice site |
probably benign |
|
|
R1778:Ddx60
|
UTSW |
8 |
61,974,176 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1840:Ddx60
|
UTSW |
8 |
61,969,553 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1970:Ddx60
|
UTSW |
8 |
61,972,206 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R2101:Ddx60
|
UTSW |
8 |
61,940,645 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,017,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
61,956,141 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
61,958,063 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,037,091 (GRCm38) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,012,436 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,037,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
61,956,144 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
61,972,220 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
61,994,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
61,948,978 (GRCm38) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
61,942,461 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
61,987,421 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,023,261 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,012,424 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
61,945,906 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
61,974,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
61,984,158 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,010,002 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
61,950,451 (GRCm38) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
61,958,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,000,578 (GRCm38) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
61,948,921 (GRCm38) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
61,948,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,012,388 (GRCm38) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
61,963,722 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
61,940,740 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,021,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,000,582 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,023,241 (GRCm38) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
61,945,940 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
61,950,578 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
61,983,905 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
61,998,681 (GRCm38) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
61,977,950 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
61,956,239 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
61,983,890 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,000,689 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,037,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
61,988,108 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
61,958,578 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
61,940,674 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
61,975,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
61,977,890 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,017,171 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,017,250 (GRCm38) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
61,977,968 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
61,998,769 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
61,942,635 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
61,974,171 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
61,956,243 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
61,974,150 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
61,958,606 (GRCm38) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
61,945,956 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
61,940,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
61,994,519 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
61,974,134 (GRCm38) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
61,989,864 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,017,841 (GRCm38) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
61,977,978 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,009,960 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
61,972,214 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,012,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,033,417 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
61,963,692 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,000,588 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGGAGTGGCATACCTTAATTTC -3'
(R):5'- GAATCCTGCTGTAACAACCTTTATCC -3'
Sequencing Primer
(F):5'- CCCTTGCAGTTGTTATATTACTGAAG -3'
(R):5'- CCCATTGTAACAATCTGTATTCCAG -3'
|
| Posted On |
2014-08-01 |
Incidental Mutation