Incidental Mutation 'R1954:Dennd4a'
| ID |
217572 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
039968-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.465)
|
| Stock # |
R1954 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 64852467 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 285
(T285S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000038890
AA Change: T285S
PolyPhen 2
Score 0.020 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: T285S
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000215025
|
| Meta Mutation Damage Score |
0.0649 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
97% (101/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts15 |
T |
A |
9: 30,910,708 (GRCm38) |
M478L |
probably benign |
Het |
| Akap8l |
T |
A |
17: 32,336,736 (GRCm38) |
Y123F |
possibly damaging |
Het |
| Anapc4 |
T |
G |
5: 52,846,625 (GRCm38) |
|
probably benign |
Het |
| Arap3 |
A |
G |
18: 37,982,002 (GRCm38) |
V987A |
probably damaging |
Het |
| Atp2b4 |
T |
A |
1: 133,739,992 (GRCm38) |
T105S |
probably damaging |
Het |
| Atp6v0d1 |
A |
G |
8: 105,565,893 (GRCm38) |
L7P |
probably damaging |
Het |
| Atp6v1b2 |
T |
C |
8: 69,105,903 (GRCm38) |
V341A |
possibly damaging |
Het |
| Baz2b |
C |
A |
2: 59,968,743 (GRCm38) |
A346S |
probably benign |
Het |
| Brpf3 |
G |
A |
17: 28,806,559 (GRCm38) |
S202N |
probably benign |
Het |
| Btnl4 |
T |
C |
17: 34,472,930 (GRCm38) |
K233E |
possibly damaging |
Het |
| Capn7 |
A |
G |
14: 31,360,150 (GRCm38) |
T438A |
probably damaging |
Het |
| Cars2 |
A |
T |
8: 11,550,286 (GRCm38) |
Y68N |
probably damaging |
Het |
| Cbx2 |
G |
T |
11: 119,028,340 (GRCm38) |
G244W |
probably damaging |
Het |
| Ccr4 |
A |
T |
9: 114,492,685 (GRCm38) |
V104D |
probably damaging |
Het |
| Cdc5l |
T |
C |
17: 45,426,516 (GRCm38) |
|
probably null |
Het |
| Cep170 |
A |
T |
1: 176,756,384 (GRCm38) |
C810S |
probably benign |
Het |
| Cfap299 |
A |
T |
5: 98,566,753 (GRCm38) |
|
probably benign |
Het |
| Clp1 |
T |
C |
2: 84,724,051 (GRCm38) |
D258G |
probably damaging |
Het |
| Clstn3 |
T |
C |
6: 124,459,298 (GRCm38) |
E164G |
possibly damaging |
Het |
| Col28a1 |
T |
C |
6: 7,998,516 (GRCm38) |
E1131G |
probably damaging |
Het |
| Cps1 |
A |
G |
1: 67,195,196 (GRCm38) |
D914G |
possibly damaging |
Het |
| Ctnnal1 |
C |
T |
4: 56,817,242 (GRCm38) |
|
probably benign |
Het |
| Cyp2c38 |
A |
G |
19: 39,404,687 (GRCm38) |
L312P |
probably damaging |
Het |
| Cytip |
T |
C |
2: 58,148,253 (GRCm38) |
N99D |
possibly damaging |
Het |
| Dhx8 |
A |
G |
11: 101,753,279 (GRCm38) |
S842G |
probably damaging |
Het |
| Disp1 |
A |
T |
1: 183,088,543 (GRCm38) |
M771K |
probably damaging |
Het |
| Dnah17 |
A |
G |
11: 118,024,731 (GRCm38) |
I4326T |
probably damaging |
Het |
| Efcab7 |
T |
C |
4: 99,900,690 (GRCm38) |
F345L |
probably damaging |
Het |
| Erc1 |
G |
T |
6: 119,797,305 (GRCm38) |
Q230K |
probably damaging |
Het |
| Ern1 |
A |
T |
11: 106,421,974 (GRCm38) |
|
probably benign |
Het |
| Espl1 |
T |
C |
15: 102,298,388 (GRCm38) |
Y96H |
probably damaging |
Het |
| Fam135a |
A |
T |
1: 24,029,602 (GRCm38) |
L533I |
probably damaging |
Het |
| Fat2 |
G |
A |
11: 55,311,084 (GRCm38) |
T388I |
probably benign |
Het |
| Galnt1 |
T |
G |
18: 24,271,774 (GRCm38) |
|
probably benign |
Het |
| Glmn |
A |
G |
5: 107,572,377 (GRCm38) |
F212S |
probably damaging |
Het |
| Gm3604 |
A |
T |
13: 62,369,211 (GRCm38) |
N444K |
probably damaging |
Het |
| Gvin-ps5 |
A |
C |
7: 106,329,681 (GRCm38) |
D336E |
probably damaging |
Het |
| H1f2 |
T |
C |
13: 23,739,402 (GRCm38) |
V185A |
unknown |
Het |
| H1f3 |
A |
G |
13: 23,555,516 (GRCm38) |
|
probably benign |
Het |
| H2-M10.3 |
T |
C |
17: 36,367,498 (GRCm38) |
D145G |
probably damaging |
Het |
| Hic2 |
T |
A |
16: 17,258,993 (GRCm38) |
L562Q |
probably damaging |
Het |
| Hip1r |
G |
T |
5: 124,001,844 (GRCm38) |
E1003D |
probably damaging |
Het |
| Hsfy2 |
C |
T |
1: 56,637,183 (GRCm38) |
C65Y |
probably benign |
Het |
| Inpp1 |
T |
C |
1: 52,794,629 (GRCm38) |
T103A |
probably damaging |
Het |
| Ints5 |
T |
C |
19: 8,894,896 (GRCm38) |
V73A |
probably damaging |
Het |
| Iqch |
A |
T |
9: 63,548,016 (GRCm38) |
D166E |
probably benign |
Het |
| Klhdc3 |
A |
T |
17: 46,677,975 (GRCm38) |
N96K |
probably damaging |
Het |
| Klk1b8 |
C |
T |
7: 43,953,848 (GRCm38) |
|
probably benign |
Het |
| Klrb1 |
T |
C |
6: 128,723,073 (GRCm38) |
|
probably null |
Het |
| Krt71 |
C |
A |
15: 101,735,466 (GRCm38) |
G446* |
probably null |
Het |
| Lars1 |
G |
A |
18: 42,210,050 (GRCm38) |
R1101C |
probably damaging |
Het |
| Lemd3 |
G |
T |
10: 120,978,940 (GRCm38) |
S129R |
probably damaging |
Het |
| Lrp1b |
A |
G |
2: 40,858,441 (GRCm38) |
L3015P |
probably damaging |
Het |
| Mdga2 |
T |
C |
12: 66,486,708 (GRCm38) |
|
probably benign |
Het |
| Mlst8 |
A |
T |
17: 24,477,221 (GRCm38) |
I178N |
probably damaging |
Het |
| Mon2 |
A |
T |
10: 123,038,483 (GRCm38) |
I320N |
probably damaging |
Het |
| Morc2b |
T |
C |
17: 33,137,490 (GRCm38) |
Y436C |
probably damaging |
Het |
| Moxd1 |
T |
A |
10: 24,279,883 (GRCm38) |
M295K |
probably benign |
Het |
| Mrps5 |
T |
A |
2: 127,596,897 (GRCm38) |
|
probably null |
Het |
| Mtor |
C |
A |
4: 148,468,273 (GRCm38) |
S744R |
probably damaging |
Het |
| Myo3a |
T |
A |
2: 22,241,226 (GRCm38) |
D61E |
probably damaging |
Het |
| Nars1 |
C |
T |
18: 64,500,564 (GRCm38) |
R545Q |
probably damaging |
Het |
| Ncoa6 |
A |
G |
2: 155,406,821 (GRCm38) |
V1521A |
possibly damaging |
Het |
| Ndor1 |
T |
C |
2: 25,255,293 (GRCm38) |
E20G |
possibly damaging |
Het |
| Nipsnap3b |
T |
C |
4: 53,017,213 (GRCm38) |
|
probably benign |
Het |
| Notch3 |
G |
T |
17: 32,166,678 (GRCm38) |
A39E |
probably benign |
Het |
| Olfr237-ps1 |
T |
C |
6: 43,153,977 (GRCm38) |
I224T |
possibly damaging |
Het |
| Or1j16 |
A |
G |
2: 36,640,215 (GRCm38) |
M59V |
possibly damaging |
Het |
| Or6z3 |
G |
T |
7: 6,461,145 (GRCm38) |
W212L |
probably benign |
Het |
| Otud3 |
T |
C |
4: 138,898,032 (GRCm38) |
K237R |
possibly damaging |
Het |
| Papola |
T |
A |
12: 105,828,273 (GRCm38) |
|
probably null |
Het |
| Parl |
T |
A |
16: 20,302,327 (GRCm38) |
M1L |
possibly damaging |
Het |
| Parp14 |
G |
T |
16: 35,858,301 (GRCm38) |
N432K |
probably benign |
Het |
| Patz1 |
T |
G |
11: 3,291,088 (GRCm38) |
S159A |
probably damaging |
Het |
| Prpf6 |
T |
G |
2: 181,632,077 (GRCm38) |
M338R |
probably benign |
Het |
| Psd3 |
A |
G |
8: 67,697,075 (GRCm38) |
L343P |
probably damaging |
Het |
| Ptpn23 |
A |
T |
9: 110,386,325 (GRCm38) |
N1422K |
probably damaging |
Het |
| Rab19 |
A |
T |
6: 39,384,082 (GRCm38) |
T55S |
probably benign |
Het |
| Sh3yl1 |
A |
G |
12: 30,922,333 (GRCm38) |
K34E |
possibly damaging |
Het |
| Skint8 |
T |
A |
4: 111,950,081 (GRCm38) |
F321L |
possibly damaging |
Het |
| Slc25a46 |
A |
T |
18: 31,600,241 (GRCm38) |
|
probably null |
Het |
| Slc26a3 |
T |
C |
12: 31,450,816 (GRCm38) |
L184S |
probably damaging |
Het |
| Slc39a10 |
A |
T |
1: 46,835,174 (GRCm38) |
S323T |
possibly damaging |
Het |
| Sorbs2 |
G |
T |
8: 45,745,738 (GRCm38) |
R20L |
probably benign |
Het |
| Stk32a |
A |
T |
18: 43,212,025 (GRCm38) |
D13V |
probably benign |
Het |
| Tab2 |
T |
C |
10: 7,919,330 (GRCm38) |
T463A |
probably damaging |
Het |
| Tenm2 |
T |
A |
11: 36,047,547 (GRCm38) |
N1433I |
possibly damaging |
Het |
| Tmem200c |
A |
T |
17: 68,840,961 (GRCm38) |
I180F |
probably damaging |
Het |
| Tmem232 |
G |
T |
17: 65,484,487 (GRCm38) |
H129N |
probably benign |
Het |
| Tmem242 |
T |
C |
17: 5,439,579 (GRCm38) |
T47A |
possibly damaging |
Het |
| Ube2d1 |
A |
T |
10: 71,285,123 (GRCm38) |
M1K |
probably null |
Het |
| Ube2frt |
A |
G |
12: 36,090,596 (GRCm38) |
|
probably benign |
Het |
| Uckl1 |
T |
C |
2: 181,570,527 (GRCm38) |
Q332R |
probably benign |
Het |
| Unc5b |
T |
C |
10: 60,769,265 (GRCm38) |
|
probably benign |
Het |
| Vmn2r114 |
T |
C |
17: 23,311,112 (GRCm38) |
Y107C |
probably benign |
Het |
| Vmn2r82 |
A |
T |
10: 79,396,056 (GRCm38) |
S630C |
probably damaging |
Het |
| Wdr25 |
T |
A |
12: 108,898,541 (GRCm38) |
V204E |
probably damaging |
Het |
| Xab2 |
T |
A |
8: 3,616,094 (GRCm38) |
D227V |
probably damaging |
Het |
| Zfp286 |
A |
G |
11: 62,783,708 (GRCm38) |
S104P |
possibly damaging |
Het |
| Zfp345 |
T |
C |
2: 150,474,821 (GRCm38) |
D22G |
probably damaging |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,906,045 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,859,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,862,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,897,336 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,886,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,852,431 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,906,920 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTTCCTAGTCCCTGACAC -3'
(R):5'- CATCTTGGATTGTCAATGCTTTCTG -3'
Sequencing Primer
(F):5'- AGTCCCTGACACCTCACCTG -3'
(R):5'- TGGAACTCACTCTGTAGACCAGG -3'
|
| Posted On |
2014-08-01 |
Incidental Mutation