Mutagenetix > Incidental Mutation

Incidental Mutation 'R1959:Hmcn1'

218095

Institutional Source

Beutler Lab

Gene Symbol

Hmcn1

Ensembl Gene

ENSMUSG00000066842

Gene Name

hemicentin 1

Synonyms

EG545370, LOC240793

MMRRC Submission

039973-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1959 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

150438275-150869186 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 150525427 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 3366 (T3366A)

Ref Sequence

ENSEMBL: ENSMUSP00000121500 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074783] [ENSMUST00000137197]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000074783
AA Change: T3366A

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)

SMART Domains

Protein: ENSMUSP00000074340
Gene: ENSMUSG00000066842
AA Change: T3366A

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
Pfam:G2F	4869	5051	1.5e-57	PFAM
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5354	4.32e-10	SMART
low complexity region	5384	5400	N/A	INTRINSIC
low complexity region	5401	5412	N/A	INTRINSIC
EGF_CA	5431	5470	2.78e-13	SMART
EGF	5474	5516	1.44e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000137197
AA Change: T3366A

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)

SMART Domains

Protein: ENSMUSP00000121500
Gene: ENSMUSG00000066842
AA Change: T3366A

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
PDB:1GL4\|A	4869	5082	3e-6	PDB
SCOP:d1gl4a1	4869	5082	3e-79	SMART
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5353	2.78e-13	SMART
EGF	5357	5399	1.44e1	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177239

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177268

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.5%
20x: 93.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(4) : Targeted(3) Gene trapped(1)

Other mutations in this stock

Total: 130 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc1	T	C	16: 14,214,257 (GRCm39)	Y191H	probably damaging	Het
Aco1	T	C	4: 40,167,193 (GRCm39)		probably null	Het
Adap1	A	G	5: 139,259,096 (GRCm39)	Y364H	probably benign	Het
Add2	T	C	6: 86,073,738 (GRCm39)	F209S	probably damaging	Het
Adgb	A	T	10: 10,270,993 (GRCm39)	D883E	probably benign	Het
Anapc1	C	A	2: 128,475,335 (GRCm39)	R1381S	probably benign	Het
Aoah	A	G	13: 20,978,564 (GRCm39)	M1V	probably null	Het
Arap1	C	A	7: 101,022,222 (GRCm39)	A8E	probably damaging	Het
Arhgap10	A	G	8: 78,136,255 (GRCm39)	F319S	possibly damaging	Het
Btrc	T	G	19: 45,515,782 (GRCm39)	I480S	probably damaging	Het
Cabin1	A	T	10: 75,570,924 (GRCm39)	V784E	possibly damaging	Het
Card9	T	A	2: 26,244,885 (GRCm39)		probably null	Het
Cdk18	A	G	1: 132,045,559 (GRCm39)	I238T	possibly damaging	Het
Clec12a	A	C	6: 129,327,444 (GRCm39)	T21P	possibly damaging	Het
Commd3	A	T	2: 18,678,774 (GRCm39)	I70F	probably benign	Het
Cspg5	G	A	9: 110,080,094 (GRCm39)	V340M	probably damaging	Het
Cyb5r4	G	A	9: 86,937,902 (GRCm39)	S307N	possibly damaging	Het
Cyp26c1	T	A	19: 37,675,825 (GRCm39)	F230I	probably damaging	Het
Ddx11	A	G	17: 66,437,723 (GRCm39)	M150V	probably benign	Het
Dennd4b	A	G	3: 90,176,080 (GRCm39)	Y190C	probably damaging	Het
Det1	A	G	7: 78,493,191 (GRCm39)	V271A	probably benign	Het
Dgkd	C	A	1: 87,857,549 (GRCm39)	P754T	possibly damaging	Het
Dhx36	T	C	3: 62,386,806 (GRCm39)	S649G	probably benign	Het
Dlgap5	A	G	14: 47,653,843 (GRCm39)	I62T	possibly damaging	Het
Dmgdh	A	G	13: 93,857,067 (GRCm39)	M724V	probably benign	Het
Dnah7a	A	G	1: 53,724,142 (GRCm39)	S108P	probably benign	Het
Dock4	A	T	12: 40,760,797 (GRCm39)	K495M	probably damaging	Het
Dse	A	G	10: 34,036,202 (GRCm39)	Y225H	probably damaging	Het
Emx1	G	A	6: 85,180,916 (GRCm39)	R211K	probably damaging	Het
Ergic2	A	G	6: 148,100,852 (GRCm39)		probably null	Het
Fbxo27	G	A	7: 28,397,797 (GRCm39)	C277Y	possibly damaging	Het
Fcrl1	T	C	3: 87,283,827 (GRCm39)	I9T	possibly damaging	Het
Fjx1	T	C	2: 102,281,152 (GRCm39)	E261G	probably benign	Het
Flacc1	A	T	1: 58,698,437 (GRCm39)	V327D	possibly damaging	Het
Flnb	C	T	14: 7,884,735 (GRCm38)	Q445*	probably null	Het
Flrt2	G	A	12: 95,747,074 (GRCm39)	V471I	probably benign	Het
Frmd4a	G	A	2: 4,539,997 (GRCm39)	V210M	probably damaging	Het
Fsip2	A	G	2: 82,821,894 (GRCm39)	K5876E	probably benign	Het
Galnt10	T	C	11: 57,656,443 (GRCm39)	L209P	probably damaging	Het
Gata5	A	T	2: 179,968,729 (GRCm39)	S382T	possibly damaging	Het
Glt6d1	C	A	2: 25,684,425 (GRCm39)	V194L	probably damaging	Het
Gm10803	T	G	2: 93,394,288 (GRCm39)	V20G	unknown	Het
Gm44511	T	G	6: 128,797,234 (GRCm39)	T52P	probably damaging	Het
Gpat4	A	T	8: 23,672,952 (GRCm39)	L88Q	possibly damaging	Het
Gpr15	T	A	16: 58,538,370 (GRCm39)	I240L	probably benign	Het
Hivep2	A	T	10: 14,008,453 (GRCm39)	I1684F	probably benign	Het
Hnmt	A	G	2: 23,893,894 (GRCm39)	V200A	possibly damaging	Het
Hps6	A	T	19: 45,992,774 (GRCm39)	H237L	probably benign	Het
Hspg2	C	T	4: 137,292,206 (GRCm39)	P4033S	probably damaging	Het
Ift70b	C	T	2: 75,767,443 (GRCm39)	E437K	probably benign	Het
Irf9	T	A	14: 55,845,174 (GRCm39)	S297T	possibly damaging	Het
Kdm3b	T	C	18: 34,945,448 (GRCm39)	V753A	possibly damaging	Het
Kif21a	G	A	15: 90,855,051 (GRCm39)	A703V	probably damaging	Het
Kif27	T	G	13: 58,440,937 (GRCm39)	R1159S	probably benign	Het
Krtap4-16	A	G	11: 99,742,373 (GRCm39)	V9A	unknown	Het
Lama2	G	T	10: 27,298,614 (GRCm39)	P161T	probably damaging	Het
Ltbp4	G	A	7: 27,028,443 (GRCm39)	P273L	unknown	Het
Lvrn	T	A	18: 47,027,784 (GRCm39)	S866R	probably damaging	Het
Med13	A	G	11: 86,189,805 (GRCm39)	Y1035H	probably damaging	Het
Mertk	T	A	2: 128,601,010 (GRCm39)	N331K	probably damaging	Het
Mios	T	A	6: 8,215,437 (GRCm39)	F211Y	probably benign	Het
Mpeg1	G	A	19: 12,440,275 (GRCm39)	V578M	probably damaging	Het
Mphosph9	A	T	5: 124,453,764 (GRCm39)	S183T	possibly damaging	Het
Mrto4	A	T	4: 139,076,949 (GRCm39)	I56N	probably damaging	Het
Muc5b	T	C	7: 141,416,374 (GRCm39)	C3107R	possibly damaging	Het
Ncoa2	A	G	1: 13,230,476 (GRCm39)	Y1023H	probably damaging	Het
Nlrp2	T	C	7: 5,330,737 (GRCm39)	E553G	probably damaging	Het
Nlrp6	GAGAAGAAGAAGAAGAAGAAGA	GAGAAGAAGAAGAAGAAGA	7: 140,504,026 (GRCm39)		probably benign	Het
Nr2f1	T	C	13: 78,337,935 (GRCm39)	T237A	probably damaging	Het
Nup205	C	A	6: 35,210,301 (GRCm39)	Q1621K	probably benign	Het
Nup50l	A	G	6: 96,142,250 (GRCm39)	S265P	possibly damaging	Het
Nxpe2	T	A	9: 48,231,026 (GRCm39)	S448C	probably benign	Het
Ogdh	T	A	11: 6,296,638 (GRCm39)	C498S	possibly damaging	Het
Oplah	G	A	15: 76,181,664 (GRCm39)	T1119I	probably damaging	Het
Or14a256	A	T	7: 86,265,639 (GRCm39)	F71L	probably benign	Het
Or2ag15	T	C	7: 106,340,601 (GRCm39)	E180G	probably damaging	Het
Or2d2	A	T	7: 106,727,717 (GRCm39)	D294E	possibly damaging	Het
Or5ak24	T	C	2: 85,260,963 (GRCm39)	D70G	probably damaging	Het
Or5d46	T	C	2: 88,170,545 (GRCm39)	L212P	probably damaging	Het
Or6p1	A	T	1: 174,258,471 (GRCm39)	K159M	probably damaging	Het
Or8s8	T	C	15: 98,354,634 (GRCm39)	S148P	probably damaging	Het
Pcdhb9	T	A	18: 37,536,369 (GRCm39)	Y788N	probably damaging	Het
Pcsk5	T	C	19: 17,410,782 (GRCm39)	D1870G	unknown	Het
Pde6g	A	G	11: 120,338,962 (GRCm39)	L76P	probably damaging	Het
Peak1	A	T	9: 56,114,073 (GRCm39)	Y593N	probably damaging	Het
Pfas	C	T	11: 68,885,110 (GRCm39)	G16R	probably damaging	Het
Pkd1l2	A	T	8: 117,769,970 (GRCm39)		probably null	Het
Pla2g3	C	T	11: 3,440,983 (GRCm39)	T316I	probably benign	Het
Ptpru	T	A	4: 131,530,788 (GRCm39)	I489F	probably damaging	Het
Rere	T	G	4: 150,553,247 (GRCm39)	H146Q	probably benign	Het
Rundc1	A	T	11: 101,322,322 (GRCm39)	Q272L	probably damaging	Het
Scml4	T	C	10: 42,832,017 (GRCm39)	L305P	probably damaging	Het
Sec16a	A	T	2: 26,320,144 (GRCm39)	H1431Q	probably benign	Het
Serpina1a	G	A	12: 103,820,059 (GRCm39)	Q373*	probably null	Het
Shank1	A	T	7: 43,974,801 (GRCm39)	N377I	unknown	Het
Shc2	T	C	10: 79,462,625 (GRCm39)		probably null	Het
Slc22a29	C	A	19: 8,146,557 (GRCm39)	R415M	probably benign	Het
Slc7a2	A	T	8: 41,368,002 (GRCm39)	I589F	probably damaging	Het
Smim8	C	T	4: 34,771,316 (GRCm39)	R26Q	probably damaging	Het
Smox	C	A	2: 131,362,384 (GRCm39)	A221D	probably damaging	Het
Sox5	A	G	6: 143,819,831 (GRCm39)	S62P	possibly damaging	Het
Spg21	A	C	9: 65,391,774 (GRCm39)	K240N	probably damaging	Het
Sv2c	C	T	13: 96,113,153 (GRCm39)	V599M	probably damaging	Het
Tanc2	T	A	11: 105,801,121 (GRCm39)	H1112Q	probably damaging	Het
Tbata	T	C	10: 61,011,623 (GRCm39)	I58T	possibly damaging	Het
Tbc1d2	T	G	4: 46,606,419 (GRCm39)	Y842S	probably benign	Het
Tctn1	A	T	5: 122,379,903 (GRCm39)		probably null	Het
Tenm1	T	C	X: 41,916,078 (GRCm39)	D402G	probably benign	Het
Tfcp2l1	T	C	1: 118,597,119 (GRCm39)	V400A	probably benign	Het
Tm9sf2	T	A	14: 122,363,576 (GRCm39)	L99I	probably benign	Het
Top2a	T	C	11: 98,886,803 (GRCm39)		probably null	Het
Traf7	C	A	17: 24,732,255 (GRCm39)	G191C	probably damaging	Het
Trpm1	T	A	7: 63,879,978 (GRCm39)	L661Q	probably damaging	Het
Ttn	T	C	2: 76,580,967 (GRCm39)	I23309V	probably benign	Het
Usp50	T	C	2: 126,619,881 (GRCm39)	K199E	possibly damaging	Het
Vmn1r218	T	C	13: 23,320,683 (GRCm39)	F10S	probably damaging	Het
Vmn2r89	C	A	14: 51,694,897 (GRCm39)	T459K	probably benign	Het
Vps13a	T	G	19: 16,655,302 (GRCm39)	S1909R	possibly damaging	Het
Vwa5b2	T	C	16: 20,420,941 (GRCm39)		probably null	Het
Vwa8	A	G	14: 79,219,800 (GRCm39)	H516R	possibly damaging	Het
Wnk1	T	C	6: 119,946,208 (GRCm39)	I648M	probably damaging	Het
Zfat	G	C	15: 68,018,392 (GRCm39)	P974R	probably benign	Het
Zfc3h1	T	A	10: 115,259,158 (GRCm39)	I1601K	probably benign	Het
Zfp239	A	G	6: 117,848,778 (GRCm39)	K172R	probably benign	Het
Zfp335	C	T	2: 164,736,722 (GRCm39)	G971D	probably damaging	Het
Zfp532	A	T	18: 65,757,563 (GRCm39)	I499F	probably damaging	Het
Zfp647	T	C	15: 76,795,314 (GRCm39)	T449A	possibly damaging	Het
Zfp938	C	T	10: 82,061,465 (GRCm39)	G385D	probably damaging	Het
Zfp959	T	G	17: 56,204,404 (GRCm39)	V147G	probably damaging	Het
Znfx1	A	T	2: 166,892,270 (GRCm39)	C649S	probably damaging	Het

Other mutations in Hmcn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00417:Hmcn1	APN	1	150,553,029 (GRCm39)	missense	probably benign
IGL00571:Hmcn1	APN	1	150,514,750 (GRCm39)	missense	probably benign	0.05
IGL00726:Hmcn1	APN	1	150,682,117 (GRCm39)	critical splice donor site	probably null
IGL00802:Hmcn1	APN	1	150,540,687 (GRCm39)	missense	probably benign	0.19
IGL00824:Hmcn1	APN	1	150,532,485 (GRCm39)	missense	probably damaging	1.00
IGL00834:Hmcn1	APN	1	150,506,091 (GRCm39)	missense	probably benign	0.00
IGL00843:Hmcn1	APN	1	150,486,464 (GRCm39)	missense	possibly damaging	0.95
IGL00845:Hmcn1	APN	1	150,480,757 (GRCm39)	missense	probably damaging	0.98
IGL00851:Hmcn1	APN	1	150,458,052 (GRCm39)	missense	probably benign	0.02
IGL00909:Hmcn1	APN	1	150,514,620 (GRCm39)	missense	probably benign	0.12
IGL01074:Hmcn1	APN	1	150,502,784 (GRCm39)	missense	possibly damaging	0.82
IGL01112:Hmcn1	APN	1	150,508,303 (GRCm39)	splice site	probably benign
IGL01304:Hmcn1	APN	1	150,498,675 (GRCm39)	missense	probably damaging	0.99
IGL01307:Hmcn1	APN	1	150,620,752 (GRCm39)	missense	possibly damaging	0.84
IGL01318:Hmcn1	APN	1	150,594,991 (GRCm39)	missense	probably damaging	1.00
IGL01403:Hmcn1	APN	1	150,468,848 (GRCm39)	missense	probably damaging	1.00
IGL01417:Hmcn1	APN	1	150,734,990 (GRCm39)	missense	probably damaging	1.00
IGL01503:Hmcn1	APN	1	150,480,823 (GRCm39)	missense	probably benign	0.38
IGL01509:Hmcn1	APN	1	150,485,382 (GRCm39)	missense	probably damaging	1.00
IGL01550:Hmcn1	APN	1	150,474,148 (GRCm39)	missense	probably damaging	1.00
IGL01601:Hmcn1	APN	1	150,503,164 (GRCm39)	missense	probably benign	0.01
IGL01617:Hmcn1	APN	1	150,547,783 (GRCm39)	missense	probably benign	0.05
IGL01636:Hmcn1	APN	1	150,455,984 (GRCm39)	missense	probably damaging	1.00
IGL01662:Hmcn1	APN	1	150,613,050 (GRCm39)	missense	possibly damaging	0.46
IGL01693:Hmcn1	APN	1	150,459,031 (GRCm39)	missense	probably damaging	1.00
IGL01723:Hmcn1	APN	1	150,620,711 (GRCm39)	missense	probably benign	0.01
IGL01776:Hmcn1	APN	1	150,547,789 (GRCm39)	missense	possibly damaging	0.70
IGL01783:Hmcn1	APN	1	150,491,051 (GRCm39)	missense	possibly damaging	0.60
IGL01789:Hmcn1	APN	1	150,566,352 (GRCm39)	missense	probably damaging	1.00
IGL01900:Hmcn1	APN	1	150,618,011 (GRCm39)	splice site	probably benign
IGL01906:Hmcn1	APN	1	150,543,638 (GRCm39)	missense	probably benign	0.01
IGL01947:Hmcn1	APN	1	150,608,643 (GRCm39)	missense	possibly damaging	0.93
IGL01958:Hmcn1	APN	1	150,479,622 (GRCm39)	missense	probably benign	0.01
IGL02002:Hmcn1	APN	1	150,491,049 (GRCm39)	missense	probably damaging	1.00
IGL02058:Hmcn1	APN	1	150,579,932 (GRCm39)	missense	probably benign	0.02
IGL02115:Hmcn1	APN	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
IGL02127:Hmcn1	APN	1	150,598,358 (GRCm39)	missense	probably benign
IGL02155:Hmcn1	APN	1	150,439,349 (GRCm39)	missense	probably damaging	1.00
IGL02222:Hmcn1	APN	1	150,682,152 (GRCm39)	missense	probably benign	0.05
IGL02293:Hmcn1	APN	1	150,540,666 (GRCm39)	missense	probably damaging	0.97
IGL02398:Hmcn1	APN	1	150,678,648 (GRCm39)	missense	possibly damaging	0.78
IGL02420:Hmcn1	APN	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
IGL02553:Hmcn1	APN	1	150,868,774 (GRCm39)	missense	probably benign	0.12
IGL02561:Hmcn1	APN	1	150,685,477 (GRCm39)	missense	probably benign	0.32
IGL02569:Hmcn1	APN	1	150,573,244 (GRCm39)	missense	probably benign	0.01
IGL02607:Hmcn1	APN	1	150,620,746 (GRCm39)	missense	possibly damaging	0.88
IGL02676:Hmcn1	APN	1	150,494,760 (GRCm39)	missense	probably benign	0.01
IGL02725:Hmcn1	APN	1	150,480,654 (GRCm39)	missense	possibly damaging	0.92
IGL02726:Hmcn1	APN	1	150,532,445 (GRCm39)	nonsense	probably null
IGL02735:Hmcn1	APN	1	150,522,583 (GRCm39)	missense	probably benign	0.02
IGL02737:Hmcn1	APN	1	150,439,579 (GRCm39)	missense	probably damaging	1.00
IGL02892:Hmcn1	APN	1	150,551,725 (GRCm39)	critical splice donor site	probably null
IGL02927:Hmcn1	APN	1	150,453,029 (GRCm39)	missense	probably damaging	1.00
IGL02931:Hmcn1	APN	1	150,532,958 (GRCm39)	missense	probably benign	0.37
IGL02936:Hmcn1	APN	1	150,573,273 (GRCm39)	missense	probably damaging	0.98
IGL02985:Hmcn1	APN	1	150,547,668 (GRCm39)	missense	probably damaging	1.00
IGL03027:Hmcn1	APN	1	150,684,290 (GRCm39)	missense	probably benign
IGL03195:Hmcn1	APN	1	150,678,660 (GRCm39)	missense	probably benign	0.06
IGL03217:Hmcn1	APN	1	150,619,418 (GRCm39)	missense	possibly damaging	0.58
IGL03232:Hmcn1	APN	1	150,646,103 (GRCm39)	splice site	probably benign
IGL03268:Hmcn1	APN	1	150,648,261 (GRCm39)	missense	probably damaging	1.00
IGL03271:Hmcn1	APN	1	150,474,175 (GRCm39)	missense	possibly damaging	0.92
IGL03304:Hmcn1	APN	1	150,505,982 (GRCm39)	missense	probably damaging	0.97
IGL03329:Hmcn1	APN	1	150,608,661 (GRCm39)	missense	probably damaging	1.00
IGL03339:Hmcn1	APN	1	150,577,720 (GRCm39)	missense	probably benign	0.04
IGL03368:Hmcn1	APN	1	150,539,623 (GRCm39)	missense	probably damaging	1.00
Backbone	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
Cambrian	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
chordate	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
Justamere	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
Lancelet	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
notochord	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
wippoorwill	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
BB004:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
BB014:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
IGL02991:Hmcn1	UTSW	1	150,614,409 (GRCm39)	missense	possibly damaging	0.56
P0017:Hmcn1	UTSW	1	150,596,440 (GRCm39)	missense	possibly damaging	0.49
PIT1430001:Hmcn1	UTSW	1	150,684,488 (GRCm39)	missense	probably benign	0.00
PIT4514001:Hmcn1	UTSW	1	150,545,238 (GRCm39)	missense	possibly damaging	0.93
R0006:Hmcn1	UTSW	1	150,684,427 (GRCm39)	missense	probably damaging	0.99
R0018:Hmcn1	UTSW	1	150,528,302 (GRCm39)	missense	probably benign	0.16
R0052:Hmcn1	UTSW	1	150,553,157 (GRCm39)	missense	probably damaging	1.00
R0107:Hmcn1	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
R0115:Hmcn1	UTSW	1	150,684,398 (GRCm39)	missense	possibly damaging	0.88
R0149:Hmcn1	UTSW	1	150,553,075 (GRCm39)	missense	probably benign	0.00
R0152:Hmcn1	UTSW	1	150,539,630 (GRCm39)	missense	probably benign	0.01
R0381:Hmcn1	UTSW	1	150,479,562 (GRCm39)	missense	probably damaging	1.00
R0398:Hmcn1	UTSW	1	150,674,565 (GRCm39)	missense	possibly damaging	0.83
R0414:Hmcn1	UTSW	1	150,591,573 (GRCm39)	missense	possibly damaging	0.72
R0494:Hmcn1	UTSW	1	150,608,543 (GRCm39)	splice site	probably benign
R0503:Hmcn1	UTSW	1	150,735,003 (GRCm39)	missense	probably damaging	1.00
R0504:Hmcn1	UTSW	1	150,752,170 (GRCm39)	splice site	probably benign
R0506:Hmcn1	UTSW	1	150,618,092 (GRCm39)	missense	possibly damaging	0.69
R0554:Hmcn1	UTSW	1	150,594,868 (GRCm39)	missense	probably benign	0.34
R0576:Hmcn1	UTSW	1	150,525,768 (GRCm39)	nonsense	probably null
R0599:Hmcn1	UTSW	1	150,485,552 (GRCm39)	missense	possibly damaging	0.91
R0605:Hmcn1	UTSW	1	150,533,127 (GRCm39)	critical splice donor site	probably null
R0607:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R0620:Hmcn1	UTSW	1	150,469,767 (GRCm39)	missense	probably benign	0.04
R0626:Hmcn1	UTSW	1	150,674,470 (GRCm39)	splice site	probably null
R0699:Hmcn1	UTSW	1	150,695,161 (GRCm39)	missense	probably damaging	1.00
R0765:Hmcn1	UTSW	1	150,684,538 (GRCm39)	missense	probably damaging	1.00
R0782:Hmcn1	UTSW	1	150,629,416 (GRCm39)	missense	possibly damaging	0.82
R0783:Hmcn1	UTSW	1	150,525,824 (GRCm39)	missense	probably damaging	1.00
R0841:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R0975:Hmcn1	UTSW	1	150,453,128 (GRCm39)	missense	probably benign	0.00
R1070:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1118:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1119:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1233:Hmcn1	UTSW	1	150,624,777 (GRCm39)	missense	probably benign
R1234:Hmcn1	UTSW	1	150,629,405 (GRCm39)	nonsense	probably null
R1291:Hmcn1	UTSW	1	150,623,942 (GRCm39)	missense	probably damaging	1.00
R1334:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1372:Hmcn1	UTSW	1	150,556,466 (GRCm39)	missense	probably benign	0.22
R1424:Hmcn1	UTSW	1	150,522,545 (GRCm39)	missense	probably benign	0.00
R1450:Hmcn1	UTSW	1	150,528,257 (GRCm39)	splice site	probably benign
R1458:Hmcn1	UTSW	1	150,485,451 (GRCm39)	missense	probably damaging	1.00
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1473:Hmcn1	UTSW	1	150,648,303 (GRCm39)	missense	probably benign	0.03
R1517:Hmcn1	UTSW	1	150,545,172 (GRCm39)	missense	probably damaging	1.00
R1527:Hmcn1	UTSW	1	150,649,554 (GRCm39)	missense	probably benign	0.00
R1557:Hmcn1	UTSW	1	150,610,283 (GRCm39)	missense	possibly damaging	0.86
R1576:Hmcn1	UTSW	1	150,532,992 (GRCm39)	missense	possibly damaging	0.77
R1617:Hmcn1	UTSW	1	150,620,778 (GRCm39)	missense	probably damaging	0.98
R1635:Hmcn1	UTSW	1	150,545,309 (GRCm39)	missense	probably benign	0.00
R1655:Hmcn1	UTSW	1	150,506,084 (GRCm39)	missense	probably benign	0.03
R1698:Hmcn1	UTSW	1	150,441,120 (GRCm39)	nonsense	probably null
R1710:Hmcn1	UTSW	1	150,551,735 (GRCm39)	missense	probably damaging	1.00
R1717:Hmcn1	UTSW	1	150,734,937 (GRCm39)	missense	probably damaging	1.00
R1753:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1756:Hmcn1	UTSW	1	150,474,781 (GRCm39)	missense	probably damaging	1.00
R1772:Hmcn1	UTSW	1	150,439,319 (GRCm39)	missense	probably damaging	0.99
R1793:Hmcn1	UTSW	1	150,624,834 (GRCm39)	missense	probably benign	0.01
R1794:Hmcn1	UTSW	1	150,502,903 (GRCm39)	missense	probably damaging	0.98
R1794:Hmcn1	UTSW	1	150,474,036 (GRCm39)	missense	probably benign	0.00
R1856:Hmcn1	UTSW	1	150,597,415 (GRCm39)	missense	probably benign	0.02
R1859:Hmcn1	UTSW	1	150,532,944 (GRCm39)	missense	probably damaging	1.00
R1862:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1865:Hmcn1	UTSW	1	150,479,563 (GRCm39)	missense	probably damaging	1.00
R1874:Hmcn1	UTSW	1	150,596,446 (GRCm39)	missense	probably damaging	1.00
R1880:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1881:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1886:Hmcn1	UTSW	1	150,453,046 (GRCm39)	missense	probably benign	0.02
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1899:Hmcn1	UTSW	1	150,533,202 (GRCm39)	missense	probably damaging	1.00
R1905:Hmcn1	UTSW	1	150,868,606 (GRCm39)	missense	probably damaging	1.00
R1912:Hmcn1	UTSW	1	150,480,633 (GRCm39)	missense	probably benign	0.28
R1960:Hmcn1	UTSW	1	150,553,127 (GRCm39)	missense	possibly damaging	0.72
R1960:Hmcn1	UTSW	1	150,551,742 (GRCm39)	missense	probably benign	0.00
R2001:Hmcn1	UTSW	1	150,614,364 (GRCm39)	missense	possibly damaging	0.81
R2011:Hmcn1	UTSW	1	150,553,085 (GRCm39)	missense	probably benign	0.01
R2075:Hmcn1	UTSW	1	150,453,074 (GRCm39)	missense	possibly damaging	0.86
R2136:Hmcn1	UTSW	1	150,509,410 (GRCm39)	missense	probably damaging	1.00
R2192:Hmcn1	UTSW	1	150,591,566 (GRCm39)	missense	probably damaging	0.97
R2267:Hmcn1	UTSW	1	150,474,761 (GRCm39)	missense	probably benign	0.00
R2268:Hmcn1	UTSW	1	150,500,349 (GRCm39)	splice site	probably benign
R2303:Hmcn1	UTSW	1	150,579,977 (GRCm39)	missense	probably damaging	1.00
R2330:Hmcn1	UTSW	1	150,528,429 (GRCm39)	splice site	probably benign
R2338:Hmcn1	UTSW	1	150,498,685 (GRCm39)	missense	possibly damaging	0.89
R2380:Hmcn1	UTSW	1	150,441,135 (GRCm39)	missense	probably benign	0.01
R2405:Hmcn1	UTSW	1	150,736,092 (GRCm39)	missense	probably damaging	1.00
R2443:Hmcn1	UTSW	1	150,474,783 (GRCm39)	missense	probably benign	0.01
R2496:Hmcn1	UTSW	1	150,490,972 (GRCm39)	missense	probably benign	0.01
R2504:Hmcn1	UTSW	1	150,562,618 (GRCm39)	nonsense	probably null
R2519:Hmcn1	UTSW	1	150,649,571 (GRCm39)	nonsense	probably null
R2520:Hmcn1	UTSW	1	150,619,398 (GRCm39)	missense	possibly damaging	0.72
R2679:Hmcn1	UTSW	1	150,528,326 (GRCm39)	missense	possibly damaging	0.67
R2831:Hmcn1	UTSW	1	150,506,403 (GRCm39)	critical splice donor site	probably null
R2847:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2849:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2873:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2897:Hmcn1	UTSW	1	150,678,624 (GRCm39)	missense	probably damaging	1.00
R2905:Hmcn1	UTSW	1	150,624,786 (GRCm39)	missense	probably damaging	1.00
R3498:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3499:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3724:Hmcn1	UTSW	1	150,565,269 (GRCm39)	missense	possibly damaging	0.82
R3765:Hmcn1	UTSW	1	150,620,776 (GRCm39)	missense	possibly damaging	0.72
R3778:Hmcn1	UTSW	1	150,678,575 (GRCm39)	missense	possibly damaging	0.95
R3790:Hmcn1	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
R3796:Hmcn1	UTSW	1	150,462,169 (GRCm39)	missense	probably damaging	1.00
R3811:Hmcn1	UTSW	1	150,525,328 (GRCm39)	critical splice donor site	probably null
R3825:Hmcn1	UTSW	1	150,462,716 (GRCm39)	missense	probably benign	0.28
R3890:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3891:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3892:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3918:Hmcn1	UTSW	1	150,566,361 (GRCm39)	missense	probably benign	0.00
R3964:Hmcn1	UTSW	1	150,449,320 (GRCm39)	missense	probably benign	0.00
R4005:Hmcn1	UTSW	1	150,598,204 (GRCm39)	missense	possibly damaging	0.88
R4026:Hmcn1	UTSW	1	150,598,120 (GRCm39)	missense	probably benign	0.03
R4037:Hmcn1	UTSW	1	150,648,253 (GRCm39)	missense	probably benign	0.00
R4088:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R4096:Hmcn1	UTSW	1	150,534,259 (GRCm39)	missense	probably benign	0.20
R4169:Hmcn1	UTSW	1	150,471,750 (GRCm39)	splice site	probably null
R4441:Hmcn1	UTSW	1	150,533,210 (GRCm39)	missense	probably null
R4493:Hmcn1	UTSW	1	150,577,650 (GRCm39)	missense	probably damaging	1.00
R4501:Hmcn1	UTSW	1	150,509,417 (GRCm39)	missense	probably damaging	1.00
R4535:Hmcn1	UTSW	1	150,439,531 (GRCm39)	missense	probably damaging	0.99
R4576:Hmcn1	UTSW	1	150,610,238 (GRCm39)	missense	probably benign
R4601:Hmcn1	UTSW	1	150,614,396 (GRCm39)	missense	probably damaging	0.99
R4627:Hmcn1	UTSW	1	150,471,645 (GRCm39)	missense	probably benign	0.11
R4647:Hmcn1	UTSW	1	150,551,262 (GRCm39)	critical splice donor site	probably null
R4657:Hmcn1	UTSW	1	150,500,301 (GRCm39)	missense	probably damaging	1.00
R4717:Hmcn1	UTSW	1	150,494,816 (GRCm39)	missense	probably benign	0.00
R4721:Hmcn1	UTSW	1	150,648,322 (GRCm39)	splice site	probably null
R4724:Hmcn1	UTSW	1	150,570,584 (GRCm39)	splice site	probably null
R4737:Hmcn1	UTSW	1	150,565,346 (GRCm39)	missense	possibly damaging	0.90
R4744:Hmcn1	UTSW	1	150,453,363 (GRCm39)	missense	probably damaging	1.00
R4795:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4796:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4871:Hmcn1	UTSW	1	150,468,836 (GRCm39)	missense	probably benign	0.02
R4895:Hmcn1	UTSW	1	150,553,130 (GRCm39)	missense	probably benign	0.00
R4934:Hmcn1	UTSW	1	150,598,286 (GRCm39)	missense	probably damaging	1.00
R4953:Hmcn1	UTSW	1	150,752,111 (GRCm39)	intron	probably benign
R4968:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.67
R4974:Hmcn1	UTSW	1	150,695,200 (GRCm39)	missense	probably benign	0.01
R5024:Hmcn1	UTSW	1	150,556,439 (GRCm39)	missense	possibly damaging	0.65
R5031:Hmcn1	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
R5093:Hmcn1	UTSW	1	150,613,007 (GRCm39)	missense	probably benign	0.14
R5096:Hmcn1	UTSW	1	150,486,420 (GRCm39)	missense	probably damaging	1.00
R5185:Hmcn1	UTSW	1	150,532,492 (GRCm39)	missense	probably benign	0.03
R5228:Hmcn1	UTSW	1	150,522,452 (GRCm39)	missense	probably benign	0.00
R5260:Hmcn1	UTSW	1	150,471,612 (GRCm39)	missense	possibly damaging	0.65
R5264:Hmcn1	UTSW	1	150,555,265 (GRCm39)	missense	probably benign	0.01
R5282:Hmcn1	UTSW	1	150,458,047 (GRCm39)	missense	probably damaging	1.00
R5334:Hmcn1	UTSW	1	150,631,123 (GRCm39)	missense	probably damaging	0.99
R5346:Hmcn1	UTSW	1	150,498,995 (GRCm39)	missense	probably damaging	1.00
R5423:Hmcn1	UTSW	1	150,577,723 (GRCm39)	missense	probably damaging	1.00
R5484:Hmcn1	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
R5491:Hmcn1	UTSW	1	150,485,576 (GRCm39)	splice site	probably null
R5531:Hmcn1	UTSW	1	150,619,539 (GRCm39)	missense	probably damaging	1.00
R5536:Hmcn1	UTSW	1	150,631,042 (GRCm39)	missense	probably benign	0.01
R5547:Hmcn1	UTSW	1	150,613,257 (GRCm39)	missense	possibly damaging	0.64
R5580:Hmcn1	UTSW	1	150,453,290 (GRCm39)	missense	probably benign	0.43
R5626:Hmcn1	UTSW	1	150,532,318 (GRCm39)	missense	probably damaging	1.00
R5657:Hmcn1	UTSW	1	150,534,313 (GRCm39)	missense	probably benign	0.02
R5677:Hmcn1	UTSW	1	150,485,529 (GRCm39)	missense	probably benign	0.00
R5718:Hmcn1	UTSW	1	150,566,351 (GRCm39)	nonsense	probably null
R5718:Hmcn1	UTSW	1	150,485,417 (GRCm39)	missense	probably damaging	1.00
R5723:Hmcn1	UTSW	1	150,570,600 (GRCm39)	missense	possibly damaging	0.95
R5739:Hmcn1	UTSW	1	150,634,225 (GRCm39)	splice site	probably null
R5739:Hmcn1	UTSW	1	150,684,448 (GRCm39)	missense	probably benign	0.45
R5751:Hmcn1	UTSW	1	150,449,305 (GRCm39)	missense	probably damaging	1.00
R5772:Hmcn1	UTSW	1	150,570,629 (GRCm39)	missense	possibly damaging	0.47
R5804:Hmcn1	UTSW	1	150,550,098 (GRCm39)	nonsense	probably null
R5809:Hmcn1	UTSW	1	150,525,358 (GRCm39)	missense	probably damaging	1.00
R5817:Hmcn1	UTSW	1	150,613,275 (GRCm39)	missense	possibly damaging	0.77
R5824:Hmcn1	UTSW	1	150,868,774 (GRCm39)	missense	probably benign	0.12
R5881:Hmcn1	UTSW	1	150,506,078 (GRCm39)	missense	probably damaging	0.99
R5928:Hmcn1	UTSW	1	150,474,648 (GRCm39)	missense	possibly damaging	0.64
R5929:Hmcn1	UTSW	1	150,453,047 (GRCm39)	nonsense	probably null
R5940:Hmcn1	UTSW	1	150,532,973 (GRCm39)	missense	probably benign	0.41
R5973:Hmcn1	UTSW	1	150,439,568 (GRCm39)	missense	probably damaging	1.00
R5997:Hmcn1	UTSW	1	150,579,924 (GRCm39)	missense	possibly damaging	0.74
R6027:Hmcn1	UTSW	1	150,678,646 (GRCm39)	missense	possibly damaging	0.79
R6029:Hmcn1	UTSW	1	150,508,188 (GRCm39)	missense	probably benign	0.13
R6056:Hmcn1	UTSW	1	150,539,660 (GRCm39)	missense	probably damaging	1.00
R6065:Hmcn1	UTSW	1	150,646,081 (GRCm39)	missense	probably benign	0.06
R6083:Hmcn1	UTSW	1	150,631,045 (GRCm39)	missense	probably damaging	1.00
R6083:Hmcn1	UTSW	1	150,631,044 (GRCm39)	missense	probably damaging	1.00
R6108:Hmcn1	UTSW	1	150,506,978 (GRCm39)	missense	possibly damaging	0.95
R6112:Hmcn1	UTSW	1	150,494,687 (GRCm39)	missense	probably damaging	1.00
R6140:Hmcn1	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
R6144:Hmcn1	UTSW	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
R6152:Hmcn1	UTSW	1	150,441,176 (GRCm39)	missense	probably damaging	1.00
R6174:Hmcn1	UTSW	1	150,522,535 (GRCm39)	missense	probably benign	0.06
R6185:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6187:Hmcn1	UTSW	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
R6276:Hmcn1	UTSW	1	150,614,432 (GRCm39)	missense	possibly damaging	0.69
R6278:Hmcn1	UTSW	1	150,573,170 (GRCm39)	critical splice donor site	probably null
R6427:Hmcn1	UTSW	1	150,573,227 (GRCm39)	missense	possibly damaging	0.85
R6431:Hmcn1	UTSW	1	150,620,711 (GRCm39)	missense	probably benign	0.01
R6441:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R6451:Hmcn1	UTSW	1	150,868,670 (GRCm39)	missense	probably damaging	1.00
R6478:Hmcn1	UTSW	1	150,540,535 (GRCm39)	missense	probably damaging	1.00
R6479:Hmcn1	UTSW	1	150,553,053 (GRCm39)	nonsense	probably null
R6490:Hmcn1	UTSW	1	150,459,029 (GRCm39)	missense	probably benign	0.00
R6525:Hmcn1	UTSW	1	150,573,317 (GRCm39)	missense	probably damaging	1.00
R6571:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6612:Hmcn1	UTSW	1	150,470,869 (GRCm39)	critical splice donor site	probably null
R6616:Hmcn1	UTSW	1	150,599,008 (GRCm39)	critical splice donor site	probably null
R6617:Hmcn1	UTSW	1	150,619,547 (GRCm39)	missense	probably benign	0.01
R6623:Hmcn1	UTSW	1	150,634,057 (GRCm39)	missense	probably benign
R6687:Hmcn1	UTSW	1	150,620,784 (GRCm39)	missense	probably benign	0.30
R6714:Hmcn1	UTSW	1	150,579,926 (GRCm39)	missense	probably damaging	0.97
R6751:Hmcn1	UTSW	1	150,610,269 (GRCm39)	missense	probably damaging	0.98
R6831:Hmcn1	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
R6971:Hmcn1	UTSW	1	150,868,802 (GRCm39)	start codon destroyed	probably benign	0.00
R7048:Hmcn1	UTSW	1	150,475,404 (GRCm39)	critical splice acceptor site	probably null
R7058:Hmcn1	UTSW	1	150,649,641 (GRCm39)	missense	probably benign	0.43
R7071:Hmcn1	UTSW	1	150,479,853 (GRCm39)	missense	probably damaging	1.00
R7078:Hmcn1	UTSW	1	150,736,118 (GRCm39)	missense	probably damaging	1.00
R7092:Hmcn1	UTSW	1	150,479,997 (GRCm39)	missense	probably damaging	1.00
R7120:Hmcn1	UTSW	1	150,576,292 (GRCm39)	missense	probably damaging	0.98
R7129:Hmcn1	UTSW	1	150,452,961 (GRCm39)	splice site	probably null
R7144:Hmcn1	UTSW	1	150,539,624 (GRCm39)	missense	probably damaging	1.00
R7148:Hmcn1	UTSW	1	150,562,605 (GRCm39)	missense	probably benign	0.00
R7162:Hmcn1	UTSW	1	150,624,744 (GRCm39)	missense	probably benign	0.18
R7172:Hmcn1	UTSW	1	150,629,450 (GRCm39)	missense	possibly damaging	0.92
R7193:Hmcn1	UTSW	1	150,525,331 (GRCm39)	missense	probably null	1.00
R7231:Hmcn1	UTSW	1	150,514,627 (GRCm39)	missense	probably benign	0.00
R7237:Hmcn1	UTSW	1	150,598,394 (GRCm39)	missense	probably damaging	0.98
R7258:Hmcn1	UTSW	1	150,591,574 (GRCm39)	missense	probably benign	0.12
R7286:Hmcn1	UTSW	1	150,458,088 (GRCm39)	missense	probably damaging	0.98
R7289:Hmcn1	UTSW	1	150,559,466 (GRCm39)	missense	possibly damaging	0.52
R7292:Hmcn1	UTSW	1	150,608,880 (GRCm39)	splice site	probably null
R7316:Hmcn1	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
R7327:Hmcn1	UTSW	1	150,479,565 (GRCm39)	missense	probably benign	0.01
R7328:Hmcn1	UTSW	1	150,514,617 (GRCm39)	missense	possibly damaging	0.95
R7346:Hmcn1	UTSW	1	150,559,496 (GRCm39)	missense	probably damaging	1.00
R7351:Hmcn1	UTSW	1	150,543,640 (GRCm39)	missense	probably damaging	0.98
R7354:Hmcn1	UTSW	1	150,682,196 (GRCm39)	nonsense	probably null
R7360:Hmcn1	UTSW	1	150,494,597 (GRCm39)	missense	probably damaging	1.00
R7396:Hmcn1	UTSW	1	150,439,382 (GRCm39)	missense	possibly damaging	0.83
R7398:Hmcn1	UTSW	1	150,522,421 (GRCm39)	missense	probably benign	0.00
R7400:Hmcn1	UTSW	1	150,550,181 (GRCm39)	missense	probably damaging	1.00
R7404:Hmcn1	UTSW	1	150,596,510 (GRCm39)	missense	probably benign	0.00
R7424:Hmcn1	UTSW	1	150,506,017 (GRCm39)	nonsense	probably null
R7454:Hmcn1	UTSW	1	150,439,355 (GRCm39)	missense	probably damaging	1.00
R7476:Hmcn1	UTSW	1	150,456,018 (GRCm39)	missense	probably damaging	0.99
R7480:Hmcn1	UTSW	1	150,552,985 (GRCm39)	critical splice donor site	probably null
R7516:Hmcn1	UTSW	1	150,498,718 (GRCm39)	missense	probably benign	0.35
R7526:Hmcn1	UTSW	1	150,532,324 (GRCm39)	missense	probably damaging	1.00
R7531:Hmcn1	UTSW	1	150,562,531 (GRCm39)	missense	probably benign	0.06
R7555:Hmcn1	UTSW	1	150,480,625 (GRCm39)	missense	probably benign	0.40
R7564:Hmcn1	UTSW	1	150,531,586 (GRCm39)	missense	probably benign
R7588:Hmcn1	UTSW	1	150,532,885 (GRCm39)	missense	possibly damaging	0.90
R7719:Hmcn1	UTSW	1	150,441,080 (GRCm39)	missense	possibly damaging	0.95
R7720:Hmcn1	UTSW	1	150,522,460 (GRCm39)	missense	probably benign	0.00
R7722:Hmcn1	UTSW	1	150,543,631 (GRCm39)	missense	probably damaging	0.98
R7761:Hmcn1	UTSW	1	150,598,196 (GRCm39)	missense	possibly damaging	0.70
R7787:Hmcn1	UTSW	1	150,632,343 (GRCm39)	missense	probably damaging	1.00
R7803:Hmcn1	UTSW	1	150,646,030 (GRCm39)	missense	probably benign	0.32
R7862:Hmcn1	UTSW	1	150,682,172 (GRCm39)	missense	probably damaging	0.96
R7876:Hmcn1	UTSW	1	150,620,722 (GRCm39)	missense	probably benign	0.03
R7886:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.94
R7891:Hmcn1	UTSW	1	150,468,940 (GRCm39)	missense	probably damaging	1.00
R7892:Hmcn1	UTSW	1	150,540,643 (GRCm39)	missense	probably benign	0.00
R7927:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
R7941:Hmcn1	UTSW	1	150,525,835 (GRCm39)	missense	possibly damaging	0.95
R7960:Hmcn1	UTSW	1	150,531,606 (GRCm39)	missense	probably damaging	1.00
R8001:Hmcn1	UTSW	1	150,540,629 (GRCm39)	nonsense	probably null
R8015:Hmcn1	UTSW	1	150,474,062 (GRCm39)	missense	possibly damaging	0.83
R8070:Hmcn1	UTSW	1	150,525,743 (GRCm39)	nonsense	probably null
R8072:Hmcn1	UTSW	1	150,532,256 (GRCm39)	missense	possibly damaging	0.62
R8113:Hmcn1	UTSW	1	150,624,841 (GRCm39)	missense	possibly damaging	0.50
R8143:Hmcn1	UTSW	1	150,734,957 (GRCm39)	missense	probably benign	0.03
R8145:Hmcn1	UTSW	1	150,629,411 (GRCm39)	missense	probably benign	0.33
R8155:Hmcn1	UTSW	1	150,480,705 (GRCm39)	missense	probably damaging	1.00
R8165:Hmcn1	UTSW	1	150,522,409 (GRCm39)	missense	probably benign	0.09
R8179:Hmcn1	UTSW	1	150,598,265 (GRCm39)	missense	probably benign	0.19
R8193:Hmcn1	UTSW	1	150,453,228 (GRCm39)	nonsense	probably null
R8234:Hmcn1	UTSW	1	150,469,761 (GRCm39)	missense	possibly damaging	0.83
R8249:Hmcn1	UTSW	1	150,695,117 (GRCm39)	missense	probably benign	0.24
R8267:Hmcn1	UTSW	1	150,735,005 (GRCm39)	missense	probably damaging	1.00
R8312:Hmcn1	UTSW	1	150,614,515 (GRCm39)	missense	probably damaging	0.99
R8338:Hmcn1	UTSW	1	150,614,485 (GRCm39)	missense	probably benign	0.35
R8354:Hmcn1	UTSW	1	150,634,142 (GRCm39)	missense	possibly damaging	0.79
R8440:Hmcn1	UTSW	1	150,570,671 (GRCm39)	missense	probably damaging	1.00
R8473:Hmcn1	UTSW	1	150,479,551 (GRCm39)	missense	possibly damaging	0.64
R8497:Hmcn1	UTSW	1	150,455,990 (GRCm39)	missense	probably benign	0.01
R8509:Hmcn1	UTSW	1	150,449,302 (GRCm39)	nonsense	probably null
R8559:Hmcn1	UTSW	1	150,551,789 (GRCm39)	missense	probably benign	0.25
R8701:Hmcn1	UTSW	1	150,631,008 (GRCm39)	missense	probably benign	0.00
R8755:Hmcn1	UTSW	1	150,509,371 (GRCm39)	missense	probably benign	0.19
R8765:Hmcn1	UTSW	1	150,556,413 (GRCm39)	missense	probably damaging	0.98
R8782:Hmcn1	UTSW	1	150,540,636 (GRCm39)	missense	probably benign	0.08
R8794:Hmcn1	UTSW	1	150,591,469 (GRCm39)	missense	probably benign	0.00
R8803:Hmcn1	UTSW	1	150,610,248 (GRCm39)	missense	probably damaging	1.00
R8808:Hmcn1	UTSW	1	150,531,570 (GRCm39)	missense	possibly damaging	0.64
R8853:Hmcn1	UTSW	1	150,547,726 (GRCm39)	missense	probably damaging	1.00
R8877:Hmcn1	UTSW	1	150,514,659 (GRCm39)	missense	probably benign	0.00
R8881:Hmcn1	UTSW	1	150,525,723 (GRCm39)	missense	probably damaging	1.00
R8916:Hmcn1	UTSW	1	150,649,530 (GRCm39)	missense	probably damaging	1.00
R9008:Hmcn1	UTSW	1	150,630,795 (GRCm39)	intron	probably benign
R9030:Hmcn1	UTSW	1	150,692,870 (GRCm39)	missense	probably benign	0.00
R9072:Hmcn1	UTSW	1	150,565,320 (GRCm39)	missense	probably benign	0.04
R9090:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9096:Hmcn1	UTSW	1	150,532,869 (GRCm39)	missense	probably benign	0.04
R9102:Hmcn1	UTSW	1	150,573,331 (GRCm39)	missense	probably benign	0.01
R9146:Hmcn1	UTSW	1	150,474,141 (GRCm39)	missense	probably benign	0.02
R9157:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9169:Hmcn1	UTSW	1	150,506,092 (GRCm39)	missense	probably damaging	0.99
R9182:Hmcn1	UTSW	1	150,488,405 (GRCm39)	missense	probably damaging	1.00
R9182:Hmcn1	UTSW	1	150,500,337 (GRCm39)	nonsense	probably null
R9204:Hmcn1	UTSW	1	150,610,262 (GRCm39)	missense	probably benign	0.40
R9219:Hmcn1	UTSW	1	150,594,844 (GRCm39)	critical splice donor site	probably null
R9267:Hmcn1	UTSW	1	150,473,740 (GRCm39)	missense	probably benign	0.26
R9271:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9274:Hmcn1	UTSW	1	150,506,046 (GRCm39)	missense	probably benign	0.01
R9313:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9414:Hmcn1	UTSW	1	150,545,187 (GRCm39)	missense	probably damaging	1.00
R9456:Hmcn1	UTSW	1	150,506,053 (GRCm39)	nonsense	probably null
R9464:Hmcn1	UTSW	1	150,599,248 (GRCm39)	missense	possibly damaging	0.80
R9474:Hmcn1	UTSW	1	150,506,471 (GRCm39)	missense	probably damaging	1.00
R9476:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9482:Hmcn1	UTSW	1	150,610,281 (GRCm39)	missense	probably benign	0.06
R9496:Hmcn1	UTSW	1	150,579,971 (GRCm39)	missense	probably benign	0.00
R9501:Hmcn1	UTSW	1	150,470,990 (GRCm39)	missense	possibly damaging	0.67
R9510:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9529:Hmcn1	UTSW	1	150,545,175 (GRCm39)	missense	probably damaging	1.00
R9566:Hmcn1	UTSW	1	150,498,660 (GRCm39)	missense	probably benign	0.00
R9608:Hmcn1	UTSW	1	150,475,303 (GRCm39)	missense	probably damaging	1.00
R9609:Hmcn1	UTSW	1	150,555,346 (GRCm39)	missense	probably damaging	0.96
R9616:Hmcn1	UTSW	1	150,684,473 (GRCm39)	missense	probably benign	0.16
R9627:Hmcn1	UTSW	1	150,506,054 (GRCm39)	missense	probably damaging	1.00
R9668:Hmcn1	UTSW	1	150,619,492 (GRCm39)	missense	probably benign	0.02
R9686:Hmcn1	UTSW	1	150,613,356 (GRCm39)	missense	probably damaging	0.99
R9717:Hmcn1	UTSW	1	150,485,378 (GRCm39)	missense	probably damaging	1.00
R9727:Hmcn1	UTSW	1	150,674,566 (GRCm39)	missense	probably benign	0.06
R9744:Hmcn1	UTSW	1	150,623,941 (GRCm39)	missense	probably damaging	1.00
R9749:Hmcn1	UTSW	1	150,632,339 (GRCm39)	missense	possibly damaging	0.94
R9761:Hmcn1	UTSW	1	150,868,625 (GRCm39)	missense	probably damaging	0.98
R9783:Hmcn1	UTSW	1	150,598,380 (GRCm39)	missense	probably benign	0.16
R9788:Hmcn1	UTSW	1	150,528,333 (GRCm39)	missense	probably benign	0.00
R9792:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9793:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9795:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9802:Hmcn1	UTSW	1	150,684,391 (GRCm39)	missense	probably benign	0.07
RF003:Hmcn1	UTSW	1	150,500,312 (GRCm39)	missense	probably damaging	1.00
RF005:Hmcn1	UTSW	1	150,510,897 (GRCm39)	nonsense	probably null
X0022:Hmcn1	UTSW	1	150,576,281 (GRCm39)	missense	probably benign	0.04
X0027:Hmcn1	UTSW	1	150,736,127 (GRCm39)	missense	probably damaging	1.00
X0028:Hmcn1	UTSW	1	150,539,652 (GRCm39)	missense	probably damaging	1.00
Z1088:Hmcn1	UTSW	1	150,524,688 (GRCm39)	missense	probably damaging	1.00
Z1176:Hmcn1	UTSW	1	150,539,668 (GRCm39)	missense	probably benign	0.12
Z1176:Hmcn1	UTSW	1	150,531,672 (GRCm39)	missense	possibly damaging	0.65
Z1176:Hmcn1	UTSW	1	150,462,196 (GRCm39)	missense	probably null	0.92

Predicted Primers

PCR Primer
(F):5'- AGCATGACTTAAACGTTGTGTAGG -3'
(R):5'- TCATTAATAGGCCACAGGTGAC -3'

Sequencing Primer
(F):5'- GGTTAAGAAGAGTTGGCAATCACTG -3'
(R):5'- GGTGACTGGAACATTTAAATGAAATC -3'

Posted On

2014-08-01