Incidental Mutation 'R0479:Wdr17'
| ID |
218510 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Wdr17
|
| Ensembl Gene |
ENSMUSG00000039375 |
| Gene Name |
WD repeat domain 17 |
| Synonyms |
B230207L18Rik, 3010002I12Rik |
| MMRRC Submission |
038679-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0479 (G1)
|
| Quality Score |
42 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
55082316-55180014 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
G to T
at 55104456 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135805
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000127511]
[ENSMUST00000127511]
[ENSMUST00000144711]
[ENSMUST00000150488]
[ENSMUST00000175915]
[ENSMUST00000175915]
|
| AlphaFold |
E9Q271 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000127511
|
| SMART Domains |
Protein: ENSMUSP00000115550
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
72 |
112 |
8.55e-8 |
SMART |
|
WD40
|
162 |
202 |
1.58e2 |
SMART |
|
WD40
|
205 |
252 |
4.26e1 |
SMART |
|
WD40
|
255 |
298 |
1.15e0 |
SMART |
|
WD40
|
383 |
422 |
1.59e-7 |
SMART |
|
WD40
|
425 |
465 |
2.39e0 |
SMART |
|
WD40
|
468 |
509 |
5.52e-2 |
SMART |
|
WD40
|
511 |
550 |
4.14e-6 |
SMART |
|
WD40
|
555 |
595 |
5.14e-11 |
SMART |
|
WD40
|
598 |
638 |
6.58e-9 |
SMART |
|
WD40
|
641 |
681 |
6.28e-6 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000127511
|
| SMART Domains |
Protein: ENSMUSP00000115550
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
72 |
112 |
8.55e-8 |
SMART |
|
WD40
|
162 |
202 |
1.58e2 |
SMART |
|
WD40
|
205 |
252 |
4.26e1 |
SMART |
|
WD40
|
255 |
298 |
1.15e0 |
SMART |
|
WD40
|
383 |
422 |
1.59e-7 |
SMART |
|
WD40
|
425 |
465 |
2.39e0 |
SMART |
|
WD40
|
468 |
509 |
5.52e-2 |
SMART |
|
WD40
|
511 |
550 |
4.14e-6 |
SMART |
|
WD40
|
555 |
595 |
5.14e-11 |
SMART |
|
WD40
|
598 |
638 |
6.58e-9 |
SMART |
|
WD40
|
641 |
681 |
6.28e-6 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128850
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000144711
|
| SMART Domains |
Protein: ENSMUSP00000117710
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
72 |
112 |
8.55e-8 |
SMART |
|
WD40
|
194 |
235 |
7.64e1 |
SMART |
|
WD40
|
238 |
281 |
1.15e0 |
SMART |
|
WD40
|
366 |
405 |
1.59e-7 |
SMART |
|
WD40
|
408 |
448 |
2.39e0 |
SMART |
|
WD40
|
451 |
492 |
5.52e-2 |
SMART |
|
WD40
|
494 |
533 |
4.14e-6 |
SMART |
|
WD40
|
538 |
578 |
5.14e-11 |
SMART |
|
WD40
|
581 |
621 |
6.58e-9 |
SMART |
|
WD40
|
624 |
664 |
6.28e-6 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000150488
|
| SMART Domains |
Protein: ENSMUSP00000122326
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
48 |
88 |
8.55e-8 |
SMART |
|
WD40
|
138 |
178 |
1.58e2 |
SMART |
|
WD40
|
181 |
228 |
4.26e1 |
SMART |
|
WD40
|
231 |
274 |
1.15e0 |
SMART |
|
WD40
|
359 |
398 |
1.59e-7 |
SMART |
|
WD40
|
401 |
441 |
2.39e0 |
SMART |
|
WD40
|
444 |
485 |
5.52e-2 |
SMART |
|
WD40
|
487 |
526 |
4.14e-6 |
SMART |
|
WD40
|
531 |
571 |
5.14e-11 |
SMART |
|
WD40
|
574 |
614 |
6.58e-9 |
SMART |
|
WD40
|
617 |
657 |
6.28e-6 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153074
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000175915
|
| SMART Domains |
Protein: ENSMUSP00000135805
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
48 |
88 |
8.55e-8 |
SMART |
|
WD40
|
138 |
178 |
1.58e2 |
SMART |
|
WD40
|
181 |
228 |
4.26e1 |
SMART |
|
WD40
|
231 |
274 |
1.15e0 |
SMART |
|
WD40
|
359 |
398 |
1.59e-7 |
SMART |
|
WD40
|
401 |
441 |
2.39e0 |
SMART |
|
WD40
|
444 |
485 |
5.52e-2 |
SMART |
|
WD40
|
487 |
526 |
4.14e-6 |
SMART |
|
WD40
|
531 |
571 |
5.14e-11 |
SMART |
|
WD40
|
574 |
614 |
6.58e-9 |
SMART |
|
WD40
|
617 |
657 |
6.28e-6 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000175915
|
| SMART Domains |
Protein: ENSMUSP00000135805
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
48 |
88 |
8.55e-8 |
SMART |
|
WD40
|
138 |
178 |
1.58e2 |
SMART |
|
WD40
|
181 |
228 |
4.26e1 |
SMART |
|
WD40
|
231 |
274 |
1.15e0 |
SMART |
|
WD40
|
359 |
398 |
1.59e-7 |
SMART |
|
WD40
|
401 |
441 |
2.39e0 |
SMART |
|
WD40
|
444 |
485 |
5.52e-2 |
SMART |
|
WD40
|
487 |
526 |
4.14e-6 |
SMART |
|
WD40
|
531 |
571 |
5.14e-11 |
SMART |
|
WD40
|
574 |
614 |
6.58e-9 |
SMART |
|
WD40
|
617 |
657 |
6.28e-6 |
SMART |
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.6%
|
| Validation Efficiency |
98% (105/107) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a WD repeat-containing protein. It is abundantly expressed in retina and testis, and is thought to be a candidate gene for retinal disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2009]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ackr1 |
A |
G |
1: 173,159,712 (GRCm39) |
V269A |
probably benign |
Het |
| Acsl1 |
G |
A |
8: 46,984,109 (GRCm39) |
G543R |
probably damaging |
Het |
| Adam18 |
T |
C |
8: 25,141,838 (GRCm39) |
N244D |
probably benign |
Het |
| Adgra3 |
C |
T |
5: 50,147,607 (GRCm39) |
V478M |
probably benign |
Het |
| Arhgap39 |
C |
T |
15: 76,619,086 (GRCm39) |
D833N |
probably damaging |
Het |
| Arhgef10 |
A |
T |
8: 15,041,070 (GRCm39) |
E723V |
probably damaging |
Het |
| Arid3a |
C |
A |
10: 79,787,128 (GRCm39) |
N519K |
possibly damaging |
Het |
| Atrn |
T |
A |
2: 130,841,085 (GRCm39) |
Y1162* |
probably null |
Het |
| Cacng5 |
T |
A |
11: 107,768,777 (GRCm39) |
N172Y |
probably benign |
Het |
| Cct8 |
C |
T |
16: 87,284,594 (GRCm39) |
V198M |
probably damaging |
Het |
| Cep192 |
G |
A |
18: 67,991,089 (GRCm39) |
S1857N |
probably damaging |
Het |
| Cherp |
A |
T |
8: 73,216,991 (GRCm39) |
D657E |
possibly damaging |
Het |
| Clca3a2 |
T |
G |
3: 144,796,610 (GRCm39) |
D199A |
probably damaging |
Het |
| Cops7b |
A |
G |
1: 86,532,798 (GRCm39) |
T219A |
probably benign |
Het |
| Crb1 |
C |
T |
1: 139,126,352 (GRCm39) |
M1392I |
probably damaging |
Het |
| Csf3r |
A |
C |
4: 125,937,616 (GRCm39) |
E833D |
probably damaging |
Het |
| Cutc |
A |
G |
19: 43,756,655 (GRCm39) |
E247G |
probably damaging |
Het |
| Cyp2c38 |
A |
G |
19: 39,451,449 (GRCm39) |
L17P |
probably damaging |
Het |
| D5Ertd615e |
T |
A |
5: 45,320,796 (GRCm39) |
|
noncoding transcript |
Het |
| Ddx60 |
G |
T |
8: 62,422,691 (GRCm39) |
G643W |
probably damaging |
Het |
| Depdc1a |
C |
T |
3: 159,226,497 (GRCm39) |
T268I |
probably damaging |
Het |
| Dgke |
T |
C |
11: 88,943,296 (GRCm39) |
E231G |
probably benign |
Het |
| Dhrs7b |
T |
A |
11: 60,746,513 (GRCm39) |
|
probably benign |
Het |
| Dll3 |
A |
G |
7: 28,000,974 (GRCm39) |
V27A |
probably damaging |
Het |
| Dnmt3c |
T |
A |
2: 153,556,861 (GRCm39) |
|
probably null |
Het |
| Duox1 |
T |
C |
2: 122,176,861 (GRCm39) |
F1461L |
probably damaging |
Het |
| Enpep |
A |
G |
3: 129,106,323 (GRCm39) |
V301A |
possibly damaging |
Het |
| Eny2 |
T |
A |
15: 44,299,000 (GRCm39) |
|
probably null |
Het |
| Esr1 |
A |
G |
10: 4,947,911 (GRCm39) |
D488G |
probably damaging |
Het |
| Ets1 |
A |
G |
9: 32,641,476 (GRCm39) |
K110E |
probably damaging |
Het |
| Eya2 |
T |
A |
2: 165,557,876 (GRCm39) |
Y157* |
probably null |
Het |
| F830045P16Rik |
T |
G |
2: 129,314,608 (GRCm39) |
D223A |
possibly damaging |
Het |
| Fbh1 |
A |
G |
2: 11,763,230 (GRCm39) |
Y475H |
probably damaging |
Het |
| Fbxo39 |
T |
C |
11: 72,208,419 (GRCm39) |
I257T |
probably damaging |
Het |
| Fkbp10 |
T |
C |
11: 100,306,740 (GRCm39) |
V23A |
probably damaging |
Het |
| Foxp3 |
A |
G |
X: 7,453,583 (GRCm39) |
I128V |
possibly damaging |
Het |
| Fzd7 |
T |
C |
1: 59,522,867 (GRCm39) |
F250S |
probably damaging |
Het |
| Gaa |
A |
G |
11: 119,172,062 (GRCm39) |
T722A |
possibly damaging |
Het |
| Gemin5 |
A |
G |
11: 58,030,377 (GRCm39) |
V816A |
probably benign |
Het |
| Glb1l3 |
T |
A |
9: 26,740,389 (GRCm39) |
T314S |
probably benign |
Het |
| H2-Ab1 |
A |
G |
17: 34,483,942 (GRCm39) |
E101G |
possibly damaging |
Het |
| Hydin |
A |
C |
8: 111,325,720 (GRCm39) |
T4710P |
probably damaging |
Het |
| Ica1 |
C |
T |
6: 8,754,627 (GRCm39) |
V48M |
probably damaging |
Het |
| Ica1 |
T |
C |
6: 8,754,683 (GRCm39) |
Y29C |
probably damaging |
Het |
| Ints7 |
T |
A |
1: 191,346,666 (GRCm39) |
|
probably null |
Het |
| Iqub |
T |
C |
6: 24,505,809 (GRCm39) |
E33G |
probably benign |
Het |
| Itgb1bp2 |
T |
A |
X: 100,492,806 (GRCm39) |
C10S |
probably damaging |
Het |
| Katnip |
T |
C |
7: 125,442,518 (GRCm39) |
L809S |
probably benign |
Het |
| Kcnd1 |
T |
A |
X: 7,697,461 (GRCm39) |
I391N |
possibly damaging |
Het |
| Kdm8 |
T |
C |
7: 125,051,812 (GRCm39) |
L135P |
probably damaging |
Het |
| Ksr1 |
T |
C |
11: 78,916,109 (GRCm39) |
D574G |
probably damaging |
Het |
| Lama5 |
C |
T |
2: 179,826,250 (GRCm39) |
R2331H |
probably benign |
Het |
| Larp1 |
C |
A |
11: 57,933,646 (GRCm39) |
N357K |
possibly damaging |
Het |
| Lgi3 |
C |
T |
14: 70,771,992 (GRCm39) |
|
probably benign |
Het |
| Lmbrd1 |
T |
A |
1: 24,785,878 (GRCm39) |
|
probably benign |
Het |
| Methig1 |
A |
T |
15: 100,272,825 (GRCm39) |
K53* |
probably null |
Het |
| Mfap3 |
T |
A |
11: 57,420,469 (GRCm39) |
I150N |
probably damaging |
Het |
| Mug1 |
A |
T |
6: 121,817,186 (GRCm39) |
Q85L |
probably benign |
Het |
| Npl |
A |
G |
1: 153,391,155 (GRCm39) |
V200A |
probably damaging |
Het |
| Nuf2 |
A |
T |
1: 169,326,503 (GRCm39) |
|
probably benign |
Het |
| Obscn |
A |
G |
11: 59,003,533 (GRCm39) |
V1255A |
probably damaging |
Het |
| Or2z8 |
C |
T |
8: 72,812,244 (GRCm39) |
T240M |
probably damaging |
Het |
| Or5h18 |
C |
T |
16: 58,847,491 (GRCm39) |
V260M |
possibly damaging |
Het |
| Or8b51 |
T |
C |
9: 38,569,478 (GRCm39) |
D70G |
probably damaging |
Het |
| P2rx1 |
T |
C |
11: 72,903,787 (GRCm39) |
V283A |
probably damaging |
Het |
| Pex2 |
C |
A |
3: 5,626,355 (GRCm39) |
L151F |
probably damaging |
Het |
| Pias1 |
A |
G |
9: 62,800,400 (GRCm39) |
|
probably benign |
Het |
| Pmfbp1 |
A |
T |
8: 110,257,105 (GRCm39) |
|
probably benign |
Het |
| Pogz |
A |
G |
3: 94,783,947 (GRCm39) |
K545E |
possibly damaging |
Het |
| Ppp3cb |
T |
C |
14: 20,553,309 (GRCm39) |
|
probably null |
Het |
| Prl |
G |
A |
13: 27,248,911 (GRCm39) |
D189N |
probably damaging |
Het |
| Prpf6 |
A |
G |
2: 181,292,920 (GRCm39) |
N794S |
probably benign |
Het |
| Prr36 |
G |
A |
8: 4,263,930 (GRCm39) |
Q579* |
probably null |
Het |
| Ptprq |
A |
T |
10: 107,479,855 (GRCm39) |
Y1138* |
probably null |
Het |
| Rabepk |
A |
T |
2: 34,675,592 (GRCm39) |
H179Q |
probably damaging |
Het |
| Rest |
T |
C |
5: 77,430,598 (GRCm39) |
S1006P |
probably damaging |
Het |
| Rimklb |
A |
C |
6: 122,441,175 (GRCm39) |
|
probably benign |
Het |
| Rnpepl1 |
T |
C |
1: 92,846,587 (GRCm39) |
|
probably benign |
Het |
| Ro60 |
A |
T |
1: 143,633,489 (GRCm39) |
D536E |
possibly damaging |
Het |
| Sacs |
T |
A |
14: 61,428,928 (GRCm39) |
L329Q |
probably damaging |
Het |
| Safb |
C |
T |
17: 56,913,025 (GRCm39) |
R914C |
probably damaging |
Het |
| Setd5 |
A |
T |
6: 113,091,994 (GRCm39) |
I272F |
probably damaging |
Het |
| Sgk1 |
G |
T |
10: 21,872,209 (GRCm39) |
A262S |
probably benign |
Het |
| Skint2 |
G |
A |
4: 112,481,238 (GRCm39) |
V34I |
possibly damaging |
Het |
| Skint5 |
G |
C |
4: 113,512,869 (GRCm39) |
Q888E |
unknown |
Het |
| Slc4a3 |
T |
C |
1: 75,528,472 (GRCm39) |
|
probably benign |
Het |
| Sox10 |
T |
C |
15: 79,047,519 (GRCm39) |
E133G |
probably damaging |
Het |
| Spryd3 |
G |
A |
15: 102,038,835 (GRCm39) |
R129* |
probably null |
Het |
| Stag1 |
T |
A |
9: 100,810,144 (GRCm39) |
N782K |
probably benign |
Het |
| Stam |
T |
C |
2: 14,122,306 (GRCm39) |
L132P |
probably damaging |
Het |
| Stard9 |
T |
A |
2: 120,528,077 (GRCm39) |
S1445T |
probably damaging |
Het |
| Syt5 |
C |
T |
7: 4,546,108 (GRCm39) |
R94Q |
probably benign |
Het |
| Tbc1d23 |
A |
T |
16: 56,992,177 (GRCm39) |
H594Q |
probably damaging |
Het |
| Tecta |
T |
A |
9: 42,249,235 (GRCm39) |
I1871F |
probably damaging |
Het |
| Tek |
A |
G |
4: 94,692,549 (GRCm39) |
D219G |
probably benign |
Het |
| Thrb |
T |
C |
14: 18,033,643 (GRCm38) |
F469L |
probably damaging |
Het |
| Tyr |
T |
C |
7: 87,142,429 (GRCm39) |
S44G |
possibly damaging |
Het |
| Usp20 |
T |
A |
2: 30,907,487 (GRCm39) |
V673E |
probably benign |
Het |
| Usp28 |
T |
C |
9: 48,948,513 (GRCm39) |
S873P |
probably damaging |
Het |
| Usp43 |
C |
T |
11: 67,788,100 (GRCm39) |
V306M |
possibly damaging |
Het |
| Wsb2 |
T |
G |
5: 117,514,744 (GRCm39) |
|
probably benign |
Het |
| Xkrx |
A |
T |
X: 133,051,715 (GRCm39) |
L312Q |
probably damaging |
Het |
|
| Other mutations in Wdr17 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00309:Wdr17
|
APN |
8 |
55,140,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00496:Wdr17
|
APN |
8 |
55,112,614 (GRCm39) |
splice site |
probably benign |
|
|
IGL01318:Wdr17
|
APN |
8 |
55,125,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01347:Wdr17
|
APN |
8 |
55,104,380 (GRCm39) |
missense |
probably benign |
|
|
IGL01654:Wdr17
|
APN |
8 |
55,115,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Wdr17
|
APN |
8 |
55,112,738 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02085:Wdr17
|
APN |
8 |
55,140,771 (GRCm39) |
nonsense |
probably null |
|
|
IGL02205:Wdr17
|
APN |
8 |
55,149,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02375:Wdr17
|
APN |
8 |
55,149,423 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02705:Wdr17
|
APN |
8 |
55,101,250 (GRCm39) |
splice site |
probably null |
|
|
IGL02719:Wdr17
|
APN |
8 |
55,146,089 (GRCm39) |
splice site |
probably null |
|
|
IGL03051:Wdr17
|
APN |
8 |
55,104,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03131:Wdr17
|
APN |
8 |
55,149,302 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03172:Wdr17
|
APN |
8 |
55,114,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
enthralled
|
UTSW |
8 |
55,112,716 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
riveted
|
UTSW |
8 |
55,085,522 (GRCm39) |
missense |
probably benign |
0.00 |
|
thrilled
|
UTSW |
8 |
55,149,303 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03138:Wdr17
|
UTSW |
8 |
55,102,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4458001:Wdr17
|
UTSW |
8 |
55,126,614 (GRCm39) |
nonsense |
probably null |
|
|
R0011:Wdr17
|
UTSW |
8 |
55,125,536 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0011:Wdr17
|
UTSW |
8 |
55,125,536 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0124:Wdr17
|
UTSW |
8 |
55,088,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0226:Wdr17
|
UTSW |
8 |
55,116,043 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0270:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0271:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0288:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0321:Wdr17
|
UTSW |
8 |
55,149,303 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0464:Wdr17
|
UTSW |
8 |
55,123,427 (GRCm39) |
splice site |
probably benign |
|
|
R0488:Wdr17
|
UTSW |
8 |
55,146,087 (GRCm39) |
unclassified |
probably benign |
|
|
R0552:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0553:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0600:Wdr17
|
UTSW |
8 |
55,114,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0621:Wdr17
|
UTSW |
8 |
55,096,226 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0655:Wdr17
|
UTSW |
8 |
55,102,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0730:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0789:Wdr17
|
UTSW |
8 |
55,112,607 (GRCm39) |
splice site |
probably benign |
|
|
R0854:Wdr17
|
UTSW |
8 |
55,156,916 (GRCm39) |
missense |
probably benign |
|
|
R0879:Wdr17
|
UTSW |
8 |
55,114,516 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1462:Wdr17
|
UTSW |
8 |
55,123,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Wdr17
|
UTSW |
8 |
55,123,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1497:Wdr17
|
UTSW |
8 |
55,125,536 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1589:Wdr17
|
UTSW |
8 |
55,156,942 (GRCm39) |
intron |
probably benign |
|
|
R1618:Wdr17
|
UTSW |
8 |
55,092,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1768:Wdr17
|
UTSW |
8 |
55,126,689 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1778:Wdr17
|
UTSW |
8 |
55,143,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1819:Wdr17
|
UTSW |
8 |
55,143,159 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1913:Wdr17
|
UTSW |
8 |
55,140,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2129:Wdr17
|
UTSW |
8 |
55,085,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Wdr17
|
UTSW |
8 |
55,125,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2309:Wdr17
|
UTSW |
8 |
55,096,283 (GRCm39) |
missense |
probably benign |
|
|
R3882:Wdr17
|
UTSW |
8 |
55,092,536 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4097:Wdr17
|
UTSW |
8 |
55,088,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4372:Wdr17
|
UTSW |
8 |
55,092,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4380:Wdr17
|
UTSW |
8 |
55,101,442 (GRCm39) |
intron |
probably benign |
|
|
R4480:Wdr17
|
UTSW |
8 |
55,117,999 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4654:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4656:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4669:Wdr17
|
UTSW |
8 |
55,143,083 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4719:Wdr17
|
UTSW |
8 |
55,092,911 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4912:Wdr17
|
UTSW |
8 |
55,082,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5000:Wdr17
|
UTSW |
8 |
55,118,161 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5073:Wdr17
|
UTSW |
8 |
55,143,271 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5176:Wdr17
|
UTSW |
8 |
55,106,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5194:Wdr17
|
UTSW |
8 |
55,140,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5270:Wdr17
|
UTSW |
8 |
55,096,221 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5300:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5325:Wdr17
|
UTSW |
8 |
55,112,716 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5336:Wdr17
|
UTSW |
8 |
55,085,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5394:Wdr17
|
UTSW |
8 |
55,092,524 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5424:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5425:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5426:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5548:Wdr17
|
UTSW |
8 |
55,156,886 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5681:Wdr17
|
UTSW |
8 |
55,115,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5722:Wdr17
|
UTSW |
8 |
55,113,806 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5894:Wdr17
|
UTSW |
8 |
55,149,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5906:Wdr17
|
UTSW |
8 |
55,092,503 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6038:Wdr17
|
UTSW |
8 |
55,085,346 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6038:Wdr17
|
UTSW |
8 |
55,085,346 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6391:Wdr17
|
UTSW |
8 |
55,114,495 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6605:Wdr17
|
UTSW |
8 |
55,134,559 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6892:Wdr17
|
UTSW |
8 |
55,126,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7019:Wdr17
|
UTSW |
8 |
55,134,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7257:Wdr17
|
UTSW |
8 |
55,085,522 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7481:Wdr17
|
UTSW |
8 |
55,114,371 (GRCm39) |
missense |
probably benign |
|
|
R7868:Wdr17
|
UTSW |
8 |
55,149,302 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7939:Wdr17
|
UTSW |
8 |
55,140,677 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7962:Wdr17
|
UTSW |
8 |
55,113,806 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8017:Wdr17
|
UTSW |
8 |
55,091,403 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8122:Wdr17
|
UTSW |
8 |
55,118,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8226:Wdr17
|
UTSW |
8 |
55,146,155 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8251:Wdr17
|
UTSW |
8 |
55,110,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8413:Wdr17
|
UTSW |
8 |
55,115,953 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8534:Wdr17
|
UTSW |
8 |
55,101,265 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8708:Wdr17
|
UTSW |
8 |
55,093,127 (GRCm39) |
intron |
probably benign |
|
|
R9116:Wdr17
|
UTSW |
8 |
55,114,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9258:Wdr17
|
UTSW |
8 |
55,112,654 (GRCm39) |
nonsense |
probably null |
|
|
R9351:Wdr17
|
UTSW |
8 |
55,143,057 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9475:Wdr17
|
UTSW |
8 |
55,088,512 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9546:Wdr17
|
UTSW |
8 |
55,112,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Wdr17
|
UTSW |
8 |
55,112,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9635:Wdr17
|
UTSW |
8 |
55,101,375 (GRCm39) |
missense |
probably damaging |
0.98 |
|
V5088:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
V5622:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
V5622:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
X0022:Wdr17
|
UTSW |
8 |
55,092,529 (GRCm39) |
missense |
probably benign |
0.04 |
|
X0066:Wdr17
|
UTSW |
8 |
55,126,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Wdr17
|
UTSW |
8 |
55,123,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Wdr17
|
UTSW |
8 |
55,096,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Predicted Primers |
|
| Posted On |
2014-08-12 |
Incidental Mutation