Incidental Mutation 'R1966:Kdm5b'
| ID |
218903 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kdm5b
|
| Ensembl Gene |
ENSMUSG00000042207 |
| Gene Name |
lysine (K)-specific demethylase 5B |
| Synonyms |
Jarid1b, Plu1, Rb-Bp2, 2210016I17Rik, 2010009J12Rik, PLU-1, D1Ertd202e |
| MMRRC Submission |
039979-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.268)
|
| Stock # |
R1966 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
134560171-134635285 bp(+) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 134613873 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107817
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047714]
[ENSMUST00000112198]
|
| AlphaFold |
Q80Y84 |
| PDB Structure |
Solution structure of the ARID domain of Jarid1b protein [SOLUTION NMR]
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000047714
|
| SMART Domains |
Protein: ENSMUSP00000038138
Gene: ENSMUSG00000042207
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
30 |
N/A |
INTRINSIC |
|
JmjN
|
31 |
72 |
2.87e-20 |
SMART |
|
ARID
|
94 |
183 |
7.39e-32 |
SMART |
|
BRIGHT
|
98 |
188 |
1.51e-35 |
SMART |
|
low complexity region
|
228 |
239 |
N/A |
INTRINSIC |
|
PHD
|
311 |
357 |
6.15e-14 |
SMART |
|
JmjC
|
453 |
619 |
2.33e-67 |
SMART |
|
Pfam:zf-C5HC2
|
692 |
744 |
2.2e-17 |
PFAM |
|
Pfam:PLU-1
|
757 |
1088 |
5.6e-92 |
PFAM |
|
low complexity region
|
1097 |
1109 |
N/A |
INTRINSIC |
|
PHD
|
1178 |
1222 |
6.2e-10 |
SMART |
|
low complexity region
|
1225 |
1236 |
N/A |
INTRINSIC |
|
low complexity region
|
1406 |
1417 |
N/A |
INTRINSIC |
|
low complexity region
|
1470 |
1484 |
N/A |
INTRINSIC |
|
PHD
|
1486 |
1536 |
1.18e-6 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000112198
|
| SMART Domains |
Protein: ENSMUSP00000107817
Gene: ENSMUSG00000042207
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
30 |
N/A |
INTRINSIC |
|
JmjN
|
31 |
72 |
2.87e-20 |
SMART |
|
ARID
|
94 |
183 |
7.39e-32 |
SMART |
|
BRIGHT
|
98 |
188 |
1.51e-35 |
SMART |
|
low complexity region
|
228 |
239 |
N/A |
INTRINSIC |
|
PHD
|
311 |
357 |
6.15e-14 |
SMART |
|
JmjC
|
453 |
619 |
2.33e-67 |
SMART |
|
Pfam:zf-C5HC2
|
692 |
745 |
6.7e-21 |
PFAM |
|
Pfam:PLU-1
|
756 |
1088 |
6e-94 |
PFAM |
|
low complexity region
|
1097 |
1109 |
N/A |
INTRINSIC |
|
PHD
|
1178 |
1222 |
6.2e-10 |
SMART |
|
low complexity region
|
1225 |
1236 |
N/A |
INTRINSIC |
|
low complexity region
|
1406 |
1417 |
N/A |
INTRINSIC |
|
low complexity region
|
1470 |
1484 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Homozygous mutant mice display decreased body weight, decreased female fertility, lower uterine weight, and a delay in mammary development. Knockout of this gene has also been associated with embryonic lethality. [provided by RefSeq, Dec 2016]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit decreased body weight, background-sensitive premature mortality, decreased female fertility, delayed mammary gland development, decreased serum estradiol levels, and reduced mammary epithelial cell proliferation in early puberty. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810013L24Rik |
A |
G |
16: 8,830,581 (GRCm38) |
E41G |
possibly damaging |
Het |
| 2410002F23Rik |
T |
A |
7: 44,251,226 (GRCm38) |
V185E |
probably benign |
Het |
| Abca1 |
A |
C |
4: 53,050,409 (GRCm38) |
V1608G |
probably damaging |
Het |
| Ap2b1 |
T |
C |
11: 83,346,895 (GRCm38) |
I557T |
probably benign |
Het |
| Arhgef15 |
G |
T |
11: 68,954,675 (GRCm38) |
P117Q |
probably damaging |
Het |
| Arhgef39 |
T |
C |
4: 43,496,710 (GRCm38) |
S335G |
probably benign |
Het |
| Blm |
A |
T |
7: 80,513,186 (GRCm38) |
F139Y |
possibly damaging |
Het |
| Cacna2d1 |
C |
T |
5: 16,333,785 (GRCm38) |
R581* |
probably null |
Het |
| Cadps |
C |
A |
14: 12,822,450 (GRCm38) |
E97* |
probably null |
Het |
| Cavin2 |
T |
A |
1: 51,289,642 (GRCm38) |
L86Q |
probably damaging |
Het |
| Ccdc136 |
A |
G |
6: 29,418,092 (GRCm38) |
E787G |
probably damaging |
Het |
| Ccdc39 |
T |
C |
3: 33,826,480 (GRCm38) |
K446R |
probably damaging |
Het |
| Cdh23 |
T |
C |
10: 60,323,582 (GRCm38) |
Y2138C |
probably damaging |
Het |
| Cdk12 |
T |
A |
11: 98,204,090 (GRCm38) |
Y241* |
probably null |
Het |
| Clcn4 |
T |
A |
7: 7,284,185 (GRCm38) |
*688L |
probably null |
Het |
| Cntnap1 |
T |
C |
11: 101,180,386 (GRCm38) |
V375A |
possibly damaging |
Het |
| Coq5 |
T |
A |
5: 115,294,831 (GRCm38) |
|
probably null |
Het |
| Cyp4b1 |
A |
G |
4: 115,625,879 (GRCm38) |
I405T |
probably benign |
Het |
| Det1 |
T |
C |
7: 78,843,218 (GRCm38) |
Y346C |
probably damaging |
Het |
| Enpp3 |
A |
T |
10: 24,807,491 (GRCm38) |
V276E |
probably damaging |
Het |
| Epb41l2 |
G |
A |
10: 25,441,768 (GRCm38) |
R61Q |
probably benign |
Het |
| Fam76b |
G |
A |
9: 13,828,066 (GRCm38) |
|
probably null |
Het |
| Fbxo45 |
A |
T |
16: 32,233,230 (GRCm38) |
D238E |
probably benign |
Het |
| Fnip2 |
G |
A |
3: 79,493,472 (GRCm38) |
T314I |
probably benign |
Het |
| Fsip2 |
T |
C |
2: 82,992,780 (GRCm38) |
S6286P |
possibly damaging |
Het |
| Gbf1 |
T |
C |
19: 46,271,564 (GRCm38) |
F999L |
probably damaging |
Het |
| Gm14139 |
T |
A |
2: 150,191,907 (GRCm38) |
D49E |
probably benign |
Het |
| Gnao1 |
C |
A |
8: 93,944,199 (GRCm38) |
T102K |
probably benign |
Het |
| Gpatch2 |
T |
A |
1: 187,322,301 (GRCm38) |
D76E |
probably damaging |
Het |
| Gpd1l |
A |
G |
9: 114,914,394 (GRCm38) |
I146T |
probably benign |
Het |
| Grik2 |
A |
T |
10: 49,355,909 (GRCm38) |
H508Q |
probably damaging |
Het |
| Hk3 |
A |
T |
13: 55,014,455 (GRCm38) |
F112Y |
probably damaging |
Het |
| Hmcn2 |
T |
G |
2: 31,389,329 (GRCm38) |
I1781S |
probably damaging |
Het |
| Inhba |
A |
T |
13: 16,026,636 (GRCm38) |
K261M |
probably damaging |
Het |
| Jarid2 |
T |
A |
13: 44,906,276 (GRCm38) |
N661K |
probably damaging |
Het |
| Kcna2 |
T |
C |
3: 107,104,630 (GRCm38) |
S176P |
probably damaging |
Het |
| Kcnj3 |
A |
T |
2: 55,437,331 (GRCm38) |
Q44L |
probably damaging |
Het |
| Kcns1 |
G |
T |
2: 164,168,535 (GRCm38) |
F101L |
probably damaging |
Het |
| Klhl14 |
C |
T |
18: 21,554,673 (GRCm38) |
G564D |
probably damaging |
Het |
| Klhl18 |
A |
T |
9: 110,476,590 (GRCm38) |
V2E |
probably benign |
Het |
| Klhl6 |
T |
C |
16: 19,982,822 (GRCm38) |
E61G |
probably damaging |
Het |
| Krt1 |
T |
C |
15: 101,848,992 (GRCm38) |
D261G |
probably benign |
Het |
| Lama5 |
C |
A |
2: 180,188,352 (GRCm38) |
C1896F |
probably damaging |
Het |
| Lrba |
A |
G |
3: 86,605,868 (GRCm38) |
|
probably null |
Het |
| Lrch3 |
A |
G |
16: 32,914,385 (GRCm38) |
T82A |
possibly damaging |
Het |
| Maml3 |
C |
G |
3: 52,104,139 (GRCm38) |
G2A |
unknown |
Het |
| Mapkap1 |
T |
A |
2: 34,518,679 (GRCm38) |
N34K |
probably damaging |
Het |
| Muc13 |
A |
T |
16: 33,814,539 (GRCm38) |
I488F |
probably damaging |
Het |
| Muc5ac |
A |
G |
7: 141,803,376 (GRCm38) |
D1129G |
possibly damaging |
Het |
| Nacc1 |
A |
T |
8: 84,676,381 (GRCm38) |
N288K |
probably damaging |
Het |
| Nek1 |
T |
G |
8: 61,016,296 (GRCm38) |
I129R |
probably damaging |
Het |
| Nf1 |
T |
A |
11: 79,411,564 (GRCm38) |
S319R |
possibly damaging |
Het |
| Nle1 |
C |
T |
11: 82,901,788 (GRCm38) |
G432D |
probably damaging |
Het |
| Nol4l |
A |
G |
2: 153,529,455 (GRCm38) |
V103A |
probably benign |
Het |
| Oca2 |
A |
G |
7: 56,414,467 (GRCm38) |
I737V |
probably damaging |
Het |
| Olfr1270 |
T |
C |
2: 90,149,404 (GRCm38) |
S201G |
probably damaging |
Het |
| Olfr231 |
G |
T |
1: 174,117,251 (GRCm38) |
S255* |
probably null |
Het |
| Olfr346 |
G |
A |
2: 36,688,784 (GRCm38) |
V261I |
probably benign |
Het |
| Olfr358 |
A |
T |
2: 37,004,948 (GRCm38) |
F222Y |
possibly damaging |
Het |
| Olfr630 |
G |
T |
7: 103,755,168 (GRCm38) |
T139K |
probably damaging |
Het |
| Olfr655 |
A |
G |
7: 104,596,801 (GRCm38) |
C127R |
probably damaging |
Het |
| Olfr750 |
T |
A |
14: 51,071,157 (GRCm38) |
I79F |
probably damaging |
Het |
| Orc1 |
T |
A |
4: 108,612,217 (GRCm38) |
I746N |
probably damaging |
Het |
| Pbxip1 |
A |
G |
3: 89,445,488 (GRCm38) |
D147G |
probably damaging |
Het |
| Pirb |
A |
T |
7: 3,717,638 (GRCm38) |
L287Q |
probably benign |
Het |
| Plin5 |
T |
A |
17: 56,112,186 (GRCm38) |
D412V |
probably damaging |
Het |
| Plxna2 |
A |
T |
1: 194,644,700 (GRCm38) |
Y314F |
possibly damaging |
Het |
| Ppid |
A |
T |
3: 79,602,299 (GRCm38) |
K308* |
probably null |
Het |
| Prss38 |
T |
C |
11: 59,373,484 (GRCm38) |
Y219C |
probably damaging |
Het |
| Ptx3 |
C |
T |
3: 66,224,621 (GRCm38) |
R188C |
probably damaging |
Het |
| Ralgds |
T |
A |
2: 28,545,875 (GRCm38) |
V504E |
probably damaging |
Het |
| Rere |
T |
C |
4: 150,616,873 (GRCm38) |
Y1237H |
probably damaging |
Het |
| Rpp30 |
C |
T |
19: 36,089,149 (GRCm38) |
S94L |
probably damaging |
Het |
| Rrp15 |
C |
T |
1: 186,736,205 (GRCm38) |
V205I |
possibly damaging |
Het |
| Scpep1 |
A |
G |
11: 88,952,414 (GRCm38) |
W73R |
probably damaging |
Het |
| Sec23ip |
A |
G |
7: 128,755,353 (GRCm38) |
H376R |
probably damaging |
Het |
| Serping1 |
G |
T |
2: 84,765,728 (GRCm38) |
T454K |
probably damaging |
Het |
| Shtn1 |
T |
G |
19: 58,975,038 (GRCm38) |
Y615S |
probably benign |
Het |
| Slc20a2 |
C |
A |
8: 22,545,537 (GRCm38) |
P184T |
probably damaging |
Het |
| Slc22a29 |
C |
A |
19: 8,218,408 (GRCm38) |
R89L |
probably damaging |
Het |
| Slc2a2 |
A |
G |
3: 28,719,485 (GRCm38) |
Q313R |
probably damaging |
Het |
| Tas2r122 |
A |
T |
6: 132,711,194 (GRCm38) |
Y245* |
probably null |
Het |
| Ticrr |
C |
A |
7: 79,694,735 (GRCm38) |
C1449* |
probably null |
Het |
| Tmem181a |
T |
C |
17: 6,303,226 (GRCm38) |
V412A |
probably benign |
Het |
| Tmtc4 |
T |
A |
14: 122,927,599 (GRCm38) |
E616V |
probably benign |
Het |
| Tnrc6b |
A |
G |
15: 80,880,439 (GRCm38) |
K714R |
probably damaging |
Het |
| Trpm8 |
T |
A |
1: 88,332,748 (GRCm38) |
|
probably null |
Het |
| Ubr2 |
T |
C |
17: 46,954,919 (GRCm38) |
T1163A |
probably benign |
Het |
| Ubr4 |
A |
G |
4: 139,451,244 (GRCm38) |
|
probably null |
Het |
| Ulk2 |
A |
T |
11: 61,819,471 (GRCm38) |
|
probably null |
Het |
| Ulk4 |
T |
A |
9: 121,257,116 (GRCm38) |
M350L |
probably benign |
Het |
| Vmn1r185 |
T |
C |
7: 26,611,531 (GRCm38) |
E183G |
probably benign |
Het |
| Vmn1r76 |
T |
A |
7: 11,930,514 (GRCm38) |
I223F |
probably damaging |
Het |
| Wdr27 |
T |
C |
17: 14,934,599 (GRCm38) |
T19A |
possibly damaging |
Het |
| Wdr59 |
T |
G |
8: 111,450,903 (GRCm38) |
T973P |
possibly damaging |
Het |
| Wnk2 |
A |
G |
13: 49,039,011 (GRCm38) |
S664P |
probably damaging |
Het |
| Zfp120 |
A |
T |
2: 150,117,398 (GRCm38) |
C335S |
probably damaging |
Het |
| Zfp30 |
C |
A |
7: 29,792,452 (GRCm38) |
Q44K |
probably benign |
Het |
| Zfp541 |
T |
C |
7: 16,079,071 (GRCm38) |
S550P |
probably benign |
Het |
| Zw10 |
C |
A |
9: 49,068,833 (GRCm38) |
N421K |
probably damaging |
Het |
|
| Other mutations in Kdm5b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00230:Kdm5b
|
APN |
1 |
134,620,955 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01458:Kdm5b
|
APN |
1 |
134,621,986 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
IGL01567:Kdm5b
|
APN |
1 |
134,602,540 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01625:Kdm5b
|
APN |
1 |
134,617,968 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
IGL01970:Kdm5b
|
APN |
1 |
134,600,727 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02183:Kdm5b
|
APN |
1 |
134,624,931 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02592:Kdm5b
|
APN |
1 |
134,624,853 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02695:Kdm5b
|
APN |
1 |
134,604,485 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL02697:Kdm5b
|
APN |
1 |
134,588,773 (GRCm38) |
splice site |
probably benign |
|
|
IGL03036:Kdm5b
|
APN |
1 |
134,608,937 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03056:Kdm5b
|
APN |
1 |
134,587,979 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL03206:Kdm5b
|
APN |
1 |
134,627,317 (GRCm38) |
missense |
probably benign |
|
|
IGL03342:Kdm5b
|
APN |
1 |
134,602,576 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03388:Kdm5b
|
APN |
1 |
134,627,322 (GRCm38) |
missense |
probably benign |
|
|
amaryllis
|
UTSW |
1 |
134,609,061 (GRCm38) |
critical splice donor site |
probably null |
|
|
PIT4486001:Kdm5b
|
UTSW |
1 |
134,628,685 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0233:Kdm5b
|
UTSW |
1 |
134,604,634 (GRCm38) |
splice site |
probably benign |
|
|
R0334:Kdm5b
|
UTSW |
1 |
134,604,522 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0504:Kdm5b
|
UTSW |
1 |
134,621,023 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0505:Kdm5b
|
UTSW |
1 |
134,602,571 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0521:Kdm5b
|
UTSW |
1 |
134,618,033 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R1004:Kdm5b
|
UTSW |
1 |
134,588,904 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R1087:Kdm5b
|
UTSW |
1 |
134,600,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1126:Kdm5b
|
UTSW |
1 |
134,613,991 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R1221:Kdm5b
|
UTSW |
1 |
134,599,091 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1230:Kdm5b
|
UTSW |
1 |
134,613,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1345:Kdm5b
|
UTSW |
1 |
134,630,550 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1482:Kdm5b
|
UTSW |
1 |
134,624,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1582:Kdm5b
|
UTSW |
1 |
134,624,853 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1653:Kdm5b
|
UTSW |
1 |
134,602,481 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1693:Kdm5b
|
UTSW |
1 |
134,597,576 (GRCm38) |
splice site |
probably benign |
|
|
R1721:Kdm5b
|
UTSW |
1 |
134,613,181 (GRCm38) |
splice site |
probably benign |
|
|
R1741:Kdm5b
|
UTSW |
1 |
134,618,017 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1762:Kdm5b
|
UTSW |
1 |
134,604,467 (GRCm38) |
nonsense |
probably null |
|
|
R1820:Kdm5b
|
UTSW |
1 |
134,597,670 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R1872:Kdm5b
|
UTSW |
1 |
134,624,994 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2056:Kdm5b
|
UTSW |
1 |
134,613,214 (GRCm38) |
missense |
probably benign |
0.05 |
|
R2059:Kdm5b
|
UTSW |
1 |
134,613,214 (GRCm38) |
missense |
probably benign |
0.05 |
|
R2405:Kdm5b
|
UTSW |
1 |
134,609,016 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3417:Kdm5b
|
UTSW |
1 |
134,587,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3771:Kdm5b
|
UTSW |
1 |
134,613,345 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3783:Kdm5b
|
UTSW |
1 |
134,630,542 (GRCm38) |
missense |
probably benign |
|
|
R3803:Kdm5b
|
UTSW |
1 |
134,615,941 (GRCm38) |
missense |
probably benign |
0.07 |
|
R3980:Kdm5b
|
UTSW |
1 |
134,619,670 (GRCm38) |
missense |
probably benign |
0.11 |
|
R3983:Kdm5b
|
UTSW |
1 |
134,631,304 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4013:Kdm5b
|
UTSW |
1 |
134,627,329 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4162:Kdm5b
|
UTSW |
1 |
134,625,161 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4701:Kdm5b
|
UTSW |
1 |
134,606,012 (GRCm38) |
intron |
probably benign |
|
|
R4791:Kdm5b
|
UTSW |
1 |
134,630,800 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4836:Kdm5b
|
UTSW |
1 |
134,593,315 (GRCm38) |
splice site |
probably null |
|
|
R4924:Kdm5b
|
UTSW |
1 |
134,631,351 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5135:Kdm5b
|
UTSW |
1 |
134,588,746 (GRCm38) |
intron |
probably benign |
|
|
R5248:Kdm5b
|
UTSW |
1 |
134,620,997 (GRCm38) |
missense |
probably benign |
0.11 |
|
R5290:Kdm5b
|
UTSW |
1 |
134,622,099 (GRCm38) |
splice site |
probably null |
|
|
R5358:Kdm5b
|
UTSW |
1 |
134,607,694 (GRCm38) |
nonsense |
probably null |
|
|
R5388:Kdm5b
|
UTSW |
1 |
134,608,897 (GRCm38) |
nonsense |
probably null |
|
|
R5396:Kdm5b
|
UTSW |
1 |
134,622,098 (GRCm38) |
splice site |
probably null |
|
|
R5397:Kdm5b
|
UTSW |
1 |
134,622,098 (GRCm38) |
splice site |
probably null |
|
|
R5398:Kdm5b
|
UTSW |
1 |
134,622,098 (GRCm38) |
splice site |
probably null |
|
|
R5399:Kdm5b
|
UTSW |
1 |
134,622,098 (GRCm38) |
splice site |
probably null |
|
|
R5529:Kdm5b
|
UTSW |
1 |
134,588,003 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5540:Kdm5b
|
UTSW |
1 |
134,631,241 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5661:Kdm5b
|
UTSW |
1 |
134,599,073 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5663:Kdm5b
|
UTSW |
1 |
134,630,635 (GRCm38) |
missense |
probably benign |
|
|
R5822:Kdm5b
|
UTSW |
1 |
134,588,773 (GRCm38) |
splice site |
probably benign |
|
|
R6226:Kdm5b
|
UTSW |
1 |
134,608,878 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6368:Kdm5b
|
UTSW |
1 |
134,599,207 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6681:Kdm5b
|
UTSW |
1 |
134,613,269 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R6715:Kdm5b
|
UTSW |
1 |
134,609,061 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7132:Kdm5b
|
UTSW |
1 |
134,599,106 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7202:Kdm5b
|
UTSW |
1 |
134,624,759 (GRCm38) |
missense |
probably benign |
|
|
R7258:Kdm5b
|
UTSW |
1 |
134,621,021 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7335:Kdm5b
|
UTSW |
1 |
134,560,439 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7420:Kdm5b
|
UTSW |
1 |
134,604,497 (GRCm38) |
missense |
probably benign |
0.14 |
|
R7426:Kdm5b
|
UTSW |
1 |
134,595,833 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7452:Kdm5b
|
UTSW |
1 |
134,624,948 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7595:Kdm5b
|
UTSW |
1 |
134,608,966 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7612:Kdm5b
|
UTSW |
1 |
134,624,918 (GRCm38) |
nonsense |
probably null |
|
|
R7704:Kdm5b
|
UTSW |
1 |
134,587,931 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7846:Kdm5b
|
UTSW |
1 |
134,617,840 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8115:Kdm5b
|
UTSW |
1 |
134,619,673 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R8146:Kdm5b
|
UTSW |
1 |
134,625,126 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8160:Kdm5b
|
UTSW |
1 |
134,613,919 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8527:Kdm5b
|
UTSW |
1 |
134,605,774 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8542:Kdm5b
|
UTSW |
1 |
134,605,774 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R8930:Kdm5b
|
UTSW |
1 |
134,616,272 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8932:Kdm5b
|
UTSW |
1 |
134,616,272 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8950:Kdm5b
|
UTSW |
1 |
134,613,926 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R9089:Kdm5b
|
UTSW |
1 |
134,607,768 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9109:Kdm5b
|
UTSW |
1 |
134,600,755 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9133:Kdm5b
|
UTSW |
1 |
134,602,585 (GRCm38) |
missense |
probably benign |
|
|
R9298:Kdm5b
|
UTSW |
1 |
134,600,755 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9423:Kdm5b
|
UTSW |
1 |
134,587,967 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R9630:Kdm5b
|
UTSW |
1 |
134,585,233 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9670:Kdm5b
|
UTSW |
1 |
134,630,502 (GRCm38) |
nonsense |
probably null |
|
|
X0063:Kdm5b
|
UTSW |
1 |
134,588,876 (GRCm38) |
missense |
probably benign |
0.07 |
|
Z1176:Kdm5b
|
UTSW |
1 |
134,625,035 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Kdm5b
|
UTSW |
1 |
134,595,798 (GRCm38) |
frame shift |
probably null |
|
|
| Predicted Primers |
|
| Posted On |
2014-08-25 |
Incidental Mutation