Incidental Mutation 'R1968:Arhgap45'
| ID |
219253 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap45
|
| Ensembl Gene |
ENSMUSG00000035697 |
| Gene Name |
Rho GTPase activating protein 45 |
| Synonyms |
6330406L22Rik, Hmha1 |
| MMRRC Submission |
039981-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1968 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
79852505-79867305 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 79863536 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 793
(I793T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043311]
[ENSMUST00000099501]
[ENSMUST00000105373]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043311
AA Change: I666T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000041019
Gene: ENSMUSG00000035697
AA Change: I666T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
142 |
153 |
N/A |
INTRINSIC |
|
FCH
|
157 |
244 |
4.14e-17 |
SMART |
|
low complexity region
|
255 |
269 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
330 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
536 |
N/A |
INTRINSIC |
|
C1
|
582 |
628 |
3.15e-8 |
SMART |
|
RhoGAP
|
653 |
852 |
2.73e-73 |
SMART |
|
low complexity region
|
856 |
869 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
876 |
999 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099501
AA Change: I782T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000097100
Gene: ENSMUSG00000035697
AA Change: I782T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
258 |
269 |
N/A |
INTRINSIC |
|
FCH
|
273 |
360 |
4.14e-17 |
SMART |
|
low complexity region
|
371 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
440 |
N/A |
INTRINSIC |
|
low complexity region
|
446 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
643 |
652 |
N/A |
INTRINSIC |
|
C1
|
698 |
744 |
3.15e-8 |
SMART |
|
RhoGAP
|
769 |
968 |
2.73e-73 |
SMART |
|
low complexity region
|
972 |
985 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
992 |
1115 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105373
AA Change: I793T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000101012
Gene: ENSMUSG00000035697
AA Change: I793T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
269 |
280 |
N/A |
INTRINSIC |
|
FCH
|
284 |
371 |
4.14e-17 |
SMART |
|
low complexity region
|
382 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
654 |
663 |
N/A |
INTRINSIC |
|
C1
|
709 |
755 |
3.15e-8 |
SMART |
|
RhoGAP
|
780 |
979 |
2.73e-73 |
SMART |
|
low complexity region
|
983 |
996 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
1003 |
1126 |
1e-21 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140974
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150022
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm4 |
A |
G |
4: 144,397,193 (GRCm39) |
Y180H |
possibly damaging |
Het |
| Abcc10 |
A |
T |
17: 46,633,125 (GRCm39) |
L528Q |
probably damaging |
Het |
| Adam18 |
T |
A |
8: 25,136,463 (GRCm39) |
T353S |
probably benign |
Het |
| Aldh1a3 |
A |
G |
7: 66,061,248 (GRCm39) |
|
probably null |
Het |
| Aldh3b2 |
T |
A |
19: 4,030,705 (GRCm39) |
M390K |
probably benign |
Het |
| Arsb |
A |
G |
13: 93,944,067 (GRCm39) |
M253V |
probably benign |
Het |
| Atcay |
T |
C |
10: 81,048,312 (GRCm39) |
D258G |
possibly damaging |
Het |
| Atf1 |
G |
T |
15: 100,152,395 (GRCm39) |
|
probably null |
Het |
| Atp1a4 |
C |
T |
1: 172,067,731 (GRCm39) |
E511K |
probably benign |
Het |
| Atp8a1 |
A |
G |
5: 67,825,000 (GRCm39) |
V777A |
probably benign |
Het |
| Baz1a |
T |
C |
12: 54,947,122 (GRCm39) |
T1173A |
possibly damaging |
Het |
| Bdh2 |
A |
T |
3: 134,991,370 (GRCm39) |
D15V |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,576,240 (GRCm39) |
Y69C |
probably damaging |
Het |
| Caskin2 |
A |
G |
11: 115,694,440 (GRCm39) |
L387P |
probably benign |
Het |
| Cat |
T |
C |
2: 103,315,334 (GRCm39) |
E17G |
probably benign |
Het |
| Ccdc15 |
T |
C |
9: 37,259,091 (GRCm39) |
I54M |
probably benign |
Het |
| Ccn1 |
T |
C |
3: 145,353,965 (GRCm39) |
Y275C |
probably damaging |
Het |
| Cdhr1 |
T |
G |
14: 36,801,682 (GRCm39) |
I754L |
probably benign |
Het |
| Cep120 |
G |
A |
18: 53,856,313 (GRCm39) |
T368I |
probably benign |
Het |
| Cep126 |
C |
A |
9: 8,100,909 (GRCm39) |
D542Y |
probably damaging |
Het |
| Cep135 |
T |
C |
5: 76,772,594 (GRCm39) |
S660P |
possibly damaging |
Het |
| Cfap70 |
A |
T |
14: 20,470,879 (GRCm39) |
S455R |
possibly damaging |
Het |
| Chd8 |
A |
G |
14: 52,458,450 (GRCm39) |
M886T |
probably damaging |
Het |
| Ckap5 |
T |
C |
2: 91,416,688 (GRCm39) |
S1098P |
probably benign |
Het |
| Clec4e |
A |
T |
6: 123,260,533 (GRCm39) |
I204N |
probably damaging |
Het |
| Cntnap5c |
G |
A |
17: 58,666,291 (GRCm39) |
R1107H |
probably damaging |
Het |
| Cramp1 |
T |
C |
17: 25,183,913 (GRCm39) |
D1234G |
probably damaging |
Het |
| Csf1r |
A |
T |
18: 61,245,867 (GRCm39) |
I275L |
probably benign |
Het |
| Cyp27a1 |
A |
G |
1: 74,776,435 (GRCm39) |
E457G |
probably benign |
Het |
| Cyp2d11 |
T |
C |
15: 82,273,749 (GRCm39) |
T410A |
probably benign |
Het |
| Cyp2d22 |
G |
C |
15: 82,257,373 (GRCm39) |
T264S |
probably benign |
Het |
| Daam2 |
G |
A |
17: 49,790,088 (GRCm39) |
R390W |
probably damaging |
Het |
| Decr2 |
T |
C |
17: 26,302,053 (GRCm39) |
S226G |
probably benign |
Het |
| Dennd6b |
T |
C |
15: 89,074,544 (GRCm39) |
D91G |
possibly damaging |
Het |
| Dglucy |
T |
C |
12: 100,825,903 (GRCm39) |
V515A |
possibly damaging |
Het |
| Dlg5 |
A |
T |
14: 24,214,187 (GRCm39) |
L734* |
probably null |
Het |
| Dop1b |
A |
G |
16: 93,579,307 (GRCm39) |
N1690D |
probably damaging |
Het |
| Exoc5 |
A |
G |
14: 49,272,347 (GRCm39) |
Y356H |
probably benign |
Het |
| Fut7 |
T |
A |
2: 25,315,738 (GRCm39) |
V332D |
probably benign |
Het |
| Gnas |
T |
C |
2: 174,140,526 (GRCm39) |
S232P |
probably damaging |
Het |
| Gramd4 |
A |
G |
15: 86,017,106 (GRCm39) |
E522G |
probably damaging |
Het |
| Gys1 |
A |
G |
7: 45,092,970 (GRCm39) |
T297A |
probably damaging |
Het |
| Herc4 |
T |
C |
10: 63,109,304 (GRCm39) |
S180P |
probably benign |
Het |
| Hivep3 |
C |
T |
4: 119,953,435 (GRCm39) |
P584S |
possibly damaging |
Het |
| Irag2 |
T |
A |
6: 145,115,499 (GRCm39) |
S310T |
probably damaging |
Het |
| Itpk1 |
G |
T |
12: 102,641,729 (GRCm39) |
|
probably null |
Het |
| Jmjd1c |
A |
T |
10: 67,061,219 (GRCm39) |
S1191C |
probably damaging |
Het |
| Lima1 |
T |
C |
15: 99,717,565 (GRCm39) |
N147S |
probably benign |
Het |
| Map4k5 |
G |
A |
12: 69,865,266 (GRCm39) |
T506I |
probably damaging |
Het |
| Mat1a |
A |
T |
14: 40,832,991 (GRCm39) |
E58V |
probably damaging |
Het |
| Mfsd13a |
T |
C |
19: 46,360,492 (GRCm39) |
L348P |
probably damaging |
Het |
| Mon2 |
A |
G |
10: 122,845,470 (GRCm39) |
Y1413H |
probably damaging |
Het |
| Mpp3 |
C |
A |
11: 101,909,378 (GRCm39) |
|
probably benign |
Het |
| Mpp4 |
T |
A |
1: 59,183,961 (GRCm39) |
I260F |
probably damaging |
Het |
| Myocd |
C |
A |
11: 65,091,733 (GRCm39) |
G70C |
probably damaging |
Het |
| Nckap1 |
C |
T |
2: 80,348,286 (GRCm39) |
S889N |
probably benign |
Het |
| Nckap5 |
T |
A |
1: 125,942,367 (GRCm39) |
D209V |
probably damaging |
Het |
| Nlrp9a |
A |
G |
7: 26,264,366 (GRCm39) |
K707R |
probably benign |
Het |
| Npr3 |
A |
G |
15: 11,905,055 (GRCm39) |
L224S |
probably benign |
Het |
| Or5m9b |
T |
A |
2: 85,905,549 (GRCm39) |
L155Q |
probably damaging |
Het |
| Or5w20 |
T |
A |
2: 87,727,383 (GRCm39) |
V280E |
probably damaging |
Het |
| Or6c74 |
A |
G |
10: 129,869,602 (GRCm39) |
S36G |
probably damaging |
Het |
| Otof |
C |
T |
5: 30,545,998 (GRCm39) |
D467N |
probably damaging |
Het |
| Paxx |
T |
C |
2: 25,350,640 (GRCm39) |
|
probably benign |
Het |
| Pcmt1 |
G |
A |
10: 7,516,474 (GRCm39) |
R179* |
probably null |
Het |
| Phkb |
T |
A |
8: 86,697,580 (GRCm39) |
V463D |
probably benign |
Het |
| Prkcq |
T |
C |
2: 11,250,208 (GRCm39) |
V175A |
probably damaging |
Het |
| Rasl11b |
T |
G |
5: 74,356,797 (GRCm39) |
I58S |
probably damaging |
Het |
| Rb1cc1 |
A |
T |
1: 6,318,419 (GRCm39) |
|
probably null |
Het |
| Reck |
T |
A |
4: 43,913,771 (GRCm39) |
|
probably null |
Het |
| Riox1 |
G |
T |
12: 83,998,156 (GRCm39) |
D231Y |
probably damaging |
Het |
| Rlf |
T |
A |
4: 121,005,617 (GRCm39) |
N1231I |
probably damaging |
Het |
| Rpn1 |
A |
G |
6: 88,072,530 (GRCm39) |
D291G |
possibly damaging |
Het |
| Samsn1 |
C |
T |
16: 75,742,461 (GRCm39) |
|
noncoding transcript |
Het |
| Scara5 |
T |
C |
14: 65,927,249 (GRCm39) |
C49R |
possibly damaging |
Het |
| Serpini1 |
A |
G |
3: 75,521,785 (GRCm39) |
D92G |
probably benign |
Het |
| Setdb2 |
A |
T |
14: 59,656,858 (GRCm39) |
L153Q |
probably damaging |
Het |
| Sh3rf3 |
C |
T |
10: 58,649,809 (GRCm39) |
T138M |
probably benign |
Het |
| Shkbp1 |
C |
T |
7: 27,054,825 (GRCm39) |
|
probably null |
Het |
| Slc22a29 |
G |
A |
19: 8,195,707 (GRCm39) |
P111S |
probably benign |
Het |
| Smarca1 |
A |
G |
X: 46,941,564 (GRCm39) |
V618A |
probably damaging |
Het |
| Spef2 |
T |
A |
15: 9,609,602 (GRCm39) |
M1308L |
probably damaging |
Het |
| Spink5 |
A |
G |
18: 44,123,775 (GRCm39) |
N354S |
probably benign |
Het |
| Srrm2 |
T |
C |
17: 24,040,465 (GRCm39) |
S2370P |
probably damaging |
Het |
| Ssxb3 |
A |
T |
X: 8,454,905 (GRCm39) |
I28N |
probably damaging |
Het |
| Sucla2 |
A |
G |
14: 73,831,119 (GRCm39) |
T411A |
probably damaging |
Het |
| Tex38 |
A |
C |
4: 115,637,537 (GRCm39) |
S89A |
probably benign |
Het |
| Tjp2 |
A |
T |
19: 24,088,437 (GRCm39) |
D723E |
probably damaging |
Het |
| Tln2 |
A |
T |
9: 67,163,183 (GRCm39) |
N1121K |
probably damaging |
Het |
| Tti1 |
T |
C |
2: 157,850,966 (GRCm39) |
E91G |
possibly damaging |
Het |
| Wbp2 |
A |
T |
11: 115,973,191 (GRCm39) |
M72K |
possibly damaging |
Het |
| Wdfy4 |
C |
A |
14: 32,828,001 (GRCm39) |
C1062F |
possibly damaging |
Het |
| Wiz |
A |
G |
17: 32,578,346 (GRCm39) |
Y389H |
probably damaging |
Het |
| Zcchc3 |
T |
C |
2: 152,256,012 (GRCm39) |
K229R |
probably damaging |
Het |
| Zmat3 |
C |
A |
3: 32,415,131 (GRCm39) |
D60Y |
probably damaging |
Het |
|
| Other mutations in Arhgap45 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01360:Arhgap45
|
APN |
10 |
79,864,482 (GRCm39) |
splice site |
probably benign |
|
|
IGL01414:Arhgap45
|
APN |
10 |
79,862,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01505:Arhgap45
|
APN |
10 |
79,862,376 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02203:Arhgap45
|
APN |
10 |
79,863,387 (GRCm39) |
nonsense |
probably null |
|
|
IGL02557:Arhgap45
|
APN |
10 |
79,857,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arhgap45
|
APN |
10 |
79,853,768 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03292:Arhgap45
|
APN |
10 |
79,856,803 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03352:Arhgap45
|
APN |
10 |
79,866,585 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Celt
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
celtic
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
druid
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
Mistletoe
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
Roman
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stonehenge
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03048:Arhgap45
|
UTSW |
10 |
79,852,851 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4677001:Arhgap45
|
UTSW |
10 |
79,856,583 (GRCm39) |
missense |
probably benign |
|
|
R0532:Arhgap45
|
UTSW |
10 |
79,857,917 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1233:Arhgap45
|
UTSW |
10 |
79,863,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Arhgap45
|
UTSW |
10 |
79,864,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1666:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1668:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1688:Arhgap45
|
UTSW |
10 |
79,864,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Arhgap45
|
UTSW |
10 |
79,853,932 (GRCm39) |
nonsense |
probably null |
|
|
R1902:Arhgap45
|
UTSW |
10 |
79,861,300 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1912:Arhgap45
|
UTSW |
10 |
79,856,524 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1935:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1955:Arhgap45
|
UTSW |
10 |
79,862,326 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1977:Arhgap45
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Arhgap45
|
UTSW |
10 |
79,856,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2074:Arhgap45
|
UTSW |
10 |
79,863,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2081:Arhgap45
|
UTSW |
10 |
79,863,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2162:Arhgap45
|
UTSW |
10 |
79,852,813 (GRCm39) |
start codon destroyed |
probably null |
0.02 |
|
R2937:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2938:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3081:Arhgap45
|
UTSW |
10 |
79,862,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4695:Arhgap45
|
UTSW |
10 |
79,861,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4736:Arhgap45
|
UTSW |
10 |
79,862,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4758:Arhgap45
|
UTSW |
10 |
79,866,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Arhgap45
|
UTSW |
10 |
79,856,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4943:Arhgap45
|
UTSW |
10 |
79,862,337 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5102:Arhgap45
|
UTSW |
10 |
79,857,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5128:Arhgap45
|
UTSW |
10 |
79,866,793 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5667:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5671:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5920:Arhgap45
|
UTSW |
10 |
79,864,965 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5998:Arhgap45
|
UTSW |
10 |
79,866,784 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6276:Arhgap45
|
UTSW |
10 |
79,862,068 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6675:Arhgap45
|
UTSW |
10 |
79,853,938 (GRCm39) |
missense |
probably null |
0.98 |
|
R6738:Arhgap45
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6783:Arhgap45
|
UTSW |
10 |
79,853,698 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6863:Arhgap45
|
UTSW |
10 |
79,853,616 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6978:Arhgap45
|
UTSW |
10 |
79,857,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7089:Arhgap45
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7215:Arhgap45
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7307:Arhgap45
|
UTSW |
10 |
79,865,016 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7308:Arhgap45
|
UTSW |
10 |
79,862,392 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7480:Arhgap45
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
R7481:Arhgap45
|
UTSW |
10 |
79,858,134 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7649:Arhgap45
|
UTSW |
10 |
79,866,835 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7652:Arhgap45
|
UTSW |
10 |
79,864,672 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7748:Arhgap45
|
UTSW |
10 |
79,852,766 (GRCm39) |
unclassified |
probably benign |
|
|
R7883:Arhgap45
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
R8121:Arhgap45
|
UTSW |
10 |
79,853,909 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8169:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8170:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8175:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8178:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8186:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8187:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8687:Arhgap45
|
UTSW |
10 |
79,852,621 (GRCm39) |
unclassified |
probably benign |
|
|
R8866:Arhgap45
|
UTSW |
10 |
79,853,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Arhgap45
|
UTSW |
10 |
79,855,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9299:Arhgap45
|
UTSW |
10 |
79,862,565 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9412:Arhgap45
|
UTSW |
10 |
79,855,564 (GRCm39) |
start codon destroyed |
probably null |
0.66 |
|
R9579:Arhgap45
|
UTSW |
10 |
79,853,843 (GRCm39) |
missense |
probably benign |
|
|
R9629:Arhgap45
|
UTSW |
10 |
79,863,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Arhgap45
|
UTSW |
10 |
79,857,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0023:Arhgap45
|
UTSW |
10 |
79,866,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
X0063:Arhgap45
|
UTSW |
10 |
79,866,190 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,864,886 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,861,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGGCCCAGCATTTACAGTAGATG -3'
(R):5'- CATTCTCAAAAGCCTGGCAC -3'
Sequencing Primer
(F):5'- CCCAGCATTTACAGTAGATGTCTGG -3'
(R):5'- TGGCACAGCTTCTCCACACG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation