Incidental Mutation 'R2008:Ppp4r4'
| ID |
219284 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ppp4r4
|
| Ensembl Gene |
ENSMUSG00000021209 |
| Gene Name |
protein phosphatase 4, regulatory subunit 4 |
| Synonyms |
8430415E04Rik |
| MMRRC Submission |
040017-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.134)
|
| Stock # |
R2008 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
103498542-103580090 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 103552016 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 195
(S195P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140874
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021631]
[ENSMUST00000187155]
[ENSMUST00000189871]
[ENSMUST00000190664]
|
| AlphaFold |
Q8C0Y0 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000021631
AA Change: S304P
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000021631
Gene: ENSMUSG00000021209
AA Change: S304P
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
55 |
577 |
6e-27 |
SMART |
|
PDB:3FGA|A
|
178 |
666 |
8e-6 |
PDB |
|
coiled coil region
|
690 |
726 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000187155
AA Change: S195P
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000140874
Gene: ENSMUSG00000021209
AA Change: S195P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HEAT
|
145 |
175 |
2.8e-3 |
PFAM |
|
low complexity region
|
484 |
495 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
617 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000189871
AA Change: S304P
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000139786
Gene: ENSMUSG00000021209
AA Change: S304P
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
95 |
577 |
7e-26 |
SMART |
|
PDB:1B3U|B
|
178 |
666 |
2e-6 |
PDB |
|
coiled coil region
|
690 |
726 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000190664
AA Change: S88P
PolyPhen 2
Score 0.974 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000140295
Gene: ENSMUSG00000021209
AA Change: S88P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HEAT
|
38 |
68 |
5.8e-4 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The encoded protein binds protein serine/threonine phosphatase 4c in the cytoplasm. [provided by RefSeq, Jan 2017]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510039O18Rik |
T |
A |
4: 148,026,034 (GRCm39) |
C185S |
probably benign |
Het |
| Acsbg3 |
A |
G |
17: 57,193,478 (GRCm39) |
N608S |
probably benign |
Het |
| Actl6b |
T |
A |
5: 137,567,592 (GRCm39) |
S409T |
probably damaging |
Het |
| Adam34l |
A |
T |
8: 44,080,074 (GRCm39) |
V50D |
probably benign |
Het |
| Adgrf2 |
T |
C |
17: 43,021,013 (GRCm39) |
T604A |
probably damaging |
Het |
| Adprs |
T |
A |
4: 126,211,137 (GRCm39) |
D260V |
probably benign |
Het |
| Akap9 |
A |
G |
5: 4,010,131 (GRCm39) |
E296G |
possibly damaging |
Het |
| Alg5 |
A |
G |
3: 54,653,894 (GRCm39) |
Y210C |
possibly damaging |
Het |
| Aoc1 |
T |
C |
6: 48,882,831 (GRCm39) |
W236R |
probably damaging |
Het |
| Atp11b |
A |
G |
3: 35,909,271 (GRCm39) |
D1155G |
probably damaging |
Het |
| Atp2c1 |
T |
A |
9: 105,309,925 (GRCm39) |
T551S |
probably benign |
Het |
| Atp7b |
A |
T |
8: 22,517,996 (GRCm39) |
C281S |
probably damaging |
Het |
| Bmp1 |
C |
T |
14: 70,729,906 (GRCm39) |
C466Y |
probably damaging |
Het |
| Cabin1 |
T |
C |
10: 75,570,810 (GRCm39) |
|
probably null |
Het |
| Capn9 |
T |
G |
8: 125,318,424 (GRCm39) |
C97G |
probably damaging |
Het |
| Cbfa2t3 |
A |
G |
8: 123,370,032 (GRCm39) |
V147A |
probably damaging |
Het |
| Ccdc83 |
T |
A |
7: 89,893,349 (GRCm39) |
Y136F |
probably damaging |
Het |
| Cdh6 |
C |
A |
15: 13,051,562 (GRCm39) |
R357L |
possibly damaging |
Het |
| Celf1 |
A |
T |
2: 90,840,753 (GRCm39) |
N367I |
probably damaging |
Het |
| Cep350 |
T |
C |
1: 155,790,467 (GRCm39) |
I1363V |
probably benign |
Het |
| Cfap299 |
C |
T |
5: 98,885,561 (GRCm39) |
T156I |
possibly damaging |
Het |
| Colec12 |
T |
A |
18: 9,874,813 (GRCm39) |
D696E |
probably benign |
Het |
| Ctbp1 |
C |
T |
5: 33,408,330 (GRCm39) |
E138K |
probably damaging |
Het |
| Cyp4a10 |
T |
C |
4: 115,382,589 (GRCm39) |
I293T |
probably damaging |
Het |
| Dclk2 |
G |
A |
3: 86,827,342 (GRCm39) |
P46S |
probably damaging |
Het |
| Dctn1 |
C |
T |
6: 83,166,938 (GRCm39) |
T263I |
probably damaging |
Het |
| Ddx49 |
A |
T |
8: 70,748,094 (GRCm39) |
V317E |
probably damaging |
Het |
| Edil3 |
G |
A |
13: 89,093,072 (GRCm39) |
|
probably null |
Het |
| Egflam |
A |
T |
15: 7,267,285 (GRCm39) |
V700E |
possibly damaging |
Het |
| Fam168b |
A |
G |
1: 34,858,946 (GRCm39) |
|
probably null |
Het |
| Gigyf2 |
T |
G |
1: 87,301,835 (GRCm39) |
|
probably null |
Het |
| H1f2 |
C |
G |
13: 23,923,392 (GRCm39) |
S187R |
probably benign |
Het |
| Heatr4 |
A |
G |
12: 84,026,514 (GRCm39) |
S248P |
probably benign |
Het |
| Hoxd1 |
A |
T |
2: 74,594,524 (GRCm39) |
I260F |
possibly damaging |
Het |
| Hsd3b3 |
A |
T |
3: 98,649,408 (GRCm39) |
L305Q |
probably damaging |
Het |
| Itch |
T |
A |
2: 155,052,379 (GRCm39) |
C660S |
possibly damaging |
Het |
| Ivd |
A |
T |
2: 118,701,981 (GRCm39) |
I138F |
probably benign |
Het |
| Katnip |
C |
G |
7: 125,459,738 (GRCm39) |
H1189D |
probably damaging |
Het |
| Lcn4 |
G |
T |
2: 26,561,228 (GRCm39) |
Q18K |
possibly damaging |
Het |
| Mapkbp1 |
T |
C |
2: 119,843,146 (GRCm39) |
Y192H |
probably damaging |
Het |
| Mn1 |
T |
C |
5: 111,566,723 (GRCm39) |
L231P |
probably damaging |
Het |
| Morc1 |
A |
G |
16: 48,386,009 (GRCm39) |
D544G |
probably benign |
Het |
| Mthfd1 |
C |
A |
12: 76,344,293 (GRCm39) |
T331K |
probably damaging |
Het |
| Myo18b |
T |
A |
5: 113,021,423 (GRCm39) |
Y546F |
probably benign |
Het |
| Nod1 |
T |
C |
6: 54,916,310 (GRCm39) |
Y129C |
probably damaging |
Het |
| Nprl3 |
A |
G |
11: 32,182,973 (GRCm39) |
V563A |
probably damaging |
Het |
| Or13a18 |
T |
C |
7: 140,190,498 (GRCm39) |
Y140H |
probably damaging |
Het |
| Or4a80 |
A |
T |
2: 89,582,417 (GRCm39) |
C252S |
possibly damaging |
Het |
| Or5g29 |
A |
G |
2: 85,421,766 (GRCm39) |
N294S |
probably damaging |
Het |
| Or5p72 |
T |
C |
7: 108,022,389 (GRCm39) |
F204L |
probably benign |
Het |
| Or8b1b |
T |
C |
9: 38,375,537 (GRCm39) |
S67P |
probably damaging |
Het |
| Orc3 |
T |
A |
4: 34,611,049 (GRCm39) |
|
probably null |
Het |
| Otog |
T |
C |
7: 45,913,498 (GRCm39) |
V777A |
probably benign |
Het |
| Pbxip1 |
G |
T |
3: 89,356,020 (GRCm39) |
V711L |
probably benign |
Het |
| Pcdhb16 |
A |
G |
18: 37,611,316 (GRCm39) |
D92G |
probably damaging |
Het |
| Phkb |
T |
A |
8: 86,783,096 (GRCm39) |
M964K |
probably damaging |
Het |
| Pitpnm2 |
T |
A |
5: 124,290,684 (GRCm39) |
M1L |
probably damaging |
Het |
| Pkhd1 |
A |
G |
1: 20,269,683 (GRCm39) |
V3287A |
probably damaging |
Het |
| Polq |
T |
A |
16: 36,882,844 (GRCm39) |
H1669Q |
probably damaging |
Het |
| Prdm2 |
T |
C |
4: 142,861,517 (GRCm39) |
Y591C |
probably damaging |
Het |
| Rgsl1 |
T |
A |
1: 153,701,651 (GRCm39) |
T268S |
possibly damaging |
Het |
| Scd2 |
A |
T |
19: 44,291,610 (GRCm39) |
T350S |
probably benign |
Het |
| Scn7a |
T |
A |
2: 66,518,091 (GRCm39) |
Q1040L |
possibly damaging |
Het |
| Sdhb |
T |
A |
4: 140,706,340 (GRCm39) |
L259Q |
probably damaging |
Het |
| Senp6 |
A |
G |
9: 80,033,680 (GRCm39) |
H701R |
probably damaging |
Het |
| Slc41a2 |
C |
T |
10: 83,140,167 (GRCm39) |
|
probably null |
Het |
| Slx4 |
T |
C |
16: 3,797,785 (GRCm39) |
D1533G |
probably damaging |
Het |
| Spef2 |
T |
C |
15: 9,713,271 (GRCm39) |
K367R |
possibly damaging |
Het |
| Sstr3 |
G |
A |
15: 78,424,711 (GRCm39) |
T12M |
probably benign |
Het |
| Synj2 |
G |
T |
17: 6,047,221 (GRCm39) |
E20D |
probably damaging |
Het |
| Tchh |
G |
T |
3: 93,353,281 (GRCm39) |
R907L |
unknown |
Het |
| Thsd1 |
A |
G |
8: 22,749,247 (GRCm39) |
E645G |
probably benign |
Het |
| Tmem176b |
A |
T |
6: 48,812,383 (GRCm39) |
M194K |
probably damaging |
Het |
| Tmprss11f |
T |
C |
5: 86,739,265 (GRCm39) |
|
probably null |
Het |
| Trim44 |
G |
A |
2: 102,230,722 (GRCm39) |
|
probably benign |
Het |
| Triml1 |
T |
A |
8: 43,583,642 (GRCm39) |
R320W |
probably damaging |
Het |
| Trmt6 |
A |
T |
2: 132,648,829 (GRCm39) |
C401* |
probably null |
Het |
| Trpv5 |
T |
C |
6: 41,636,662 (GRCm39) |
|
probably null |
Het |
| V1rd19 |
T |
A |
7: 23,702,726 (GRCm39) |
L64* |
probably null |
Het |
| Vmn1r216 |
A |
T |
13: 23,283,661 (GRCm39) |
R115W |
probably damaging |
Het |
| Vmn2r58 |
T |
C |
7: 41,509,924 (GRCm39) |
N551S |
probably damaging |
Het |
| Vmn2r77 |
T |
C |
7: 86,450,921 (GRCm39) |
V269A |
probably benign |
Het |
| Vps13d |
A |
T |
4: 144,881,813 (GRCm39) |
V1254D |
probably benign |
Het |
| Xpr1 |
T |
C |
1: 155,156,775 (GRCm39) |
|
probably null |
Het |
| Zan |
T |
A |
5: 137,450,712 (GRCm39) |
T1622S |
unknown |
Het |
| Zfp112 |
T |
C |
7: 23,826,176 (GRCm39) |
Y715H |
probably damaging |
Het |
| Zfp750 |
G |
A |
11: 121,403,951 (GRCm39) |
P308L |
possibly damaging |
Het |
|
| Other mutations in Ppp4r4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00827:Ppp4r4
|
APN |
12 |
103,545,335 (GRCm39) |
missense |
probably benign |
|
|
IGL01388:Ppp4r4
|
APN |
12 |
103,543,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01662:Ppp4r4
|
APN |
12 |
103,569,225 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01768:Ppp4r4
|
APN |
12 |
103,547,664 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL01894:Ppp4r4
|
APN |
12 |
103,559,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01921:Ppp4r4
|
APN |
12 |
103,542,569 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
IGL01960:Ppp4r4
|
APN |
12 |
103,547,753 (GRCm39) |
splice site |
probably benign |
|
|
IGL02084:Ppp4r4
|
APN |
12 |
103,566,657 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02287:Ppp4r4
|
APN |
12 |
103,553,747 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02315:Ppp4r4
|
APN |
12 |
103,566,620 (GRCm39) |
splice site |
probably benign |
|
|
IGL03137:Ppp4r4
|
APN |
12 |
103,547,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03170:Ppp4r4
|
APN |
12 |
103,557,033 (GRCm39) |
intron |
probably benign |
|
|
cataract
|
UTSW |
12 |
103,579,074 (GRCm39) |
nonsense |
probably null |
|
|
downfall
|
UTSW |
12 |
103,559,357 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0114:Ppp4r4
|
UTSW |
12 |
103,542,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0390:Ppp4r4
|
UTSW |
12 |
103,567,619 (GRCm39) |
splice site |
probably benign |
|
|
R0403:Ppp4r4
|
UTSW |
12 |
103,550,361 (GRCm39) |
missense |
probably benign |
|
|
R0548:Ppp4r4
|
UTSW |
12 |
103,579,074 (GRCm39) |
nonsense |
probably null |
|
|
R0601:Ppp4r4
|
UTSW |
12 |
103,566,779 (GRCm39) |
splice site |
probably benign |
|
|
R0894:Ppp4r4
|
UTSW |
12 |
103,566,754 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1127:Ppp4r4
|
UTSW |
12 |
103,545,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1177:Ppp4r4
|
UTSW |
12 |
103,542,582 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1378:Ppp4r4
|
UTSW |
12 |
103,547,751 (GRCm39) |
splice site |
probably benign |
|
|
R1442:Ppp4r4
|
UTSW |
12 |
103,564,504 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1497:Ppp4r4
|
UTSW |
12 |
103,573,204 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1651:Ppp4r4
|
UTSW |
12 |
103,550,331 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1797:Ppp4r4
|
UTSW |
12 |
103,564,410 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1880:Ppp4r4
|
UTSW |
12 |
103,571,294 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2038:Ppp4r4
|
UTSW |
12 |
103,542,539 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2404:Ppp4r4
|
UTSW |
12 |
103,547,749 (GRCm39) |
splice site |
probably null |
|
|
R2696:Ppp4r4
|
UTSW |
12 |
103,547,653 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2849:Ppp4r4
|
UTSW |
12 |
103,573,192 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2965:Ppp4r4
|
UTSW |
12 |
103,579,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3030:Ppp4r4
|
UTSW |
12 |
103,573,215 (GRCm39) |
missense |
probably benign |
|
|
R3805:Ppp4r4
|
UTSW |
12 |
103,566,625 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3862:Ppp4r4
|
UTSW |
12 |
103,562,680 (GRCm39) |
nonsense |
probably null |
|
|
R4194:Ppp4r4
|
UTSW |
12 |
103,524,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4320:Ppp4r4
|
UTSW |
12 |
103,564,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4558:Ppp4r4
|
UTSW |
12 |
103,573,192 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4783:Ppp4r4
|
UTSW |
12 |
103,557,117 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4866:Ppp4r4
|
UTSW |
12 |
103,566,706 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4903:Ppp4r4
|
UTSW |
12 |
103,557,030 (GRCm39) |
splice site |
probably null |
|
|
R5309:Ppp4r4
|
UTSW |
12 |
103,573,147 (GRCm39) |
splice site |
probably null |
|
|
R5312:Ppp4r4
|
UTSW |
12 |
103,573,147 (GRCm39) |
splice site |
probably null |
|
|
R5381:Ppp4r4
|
UTSW |
12 |
103,559,357 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5383:Ppp4r4
|
UTSW |
12 |
103,550,427 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5447:Ppp4r4
|
UTSW |
12 |
103,550,410 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5942:Ppp4r4
|
UTSW |
12 |
103,553,706 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6339:Ppp4r4
|
UTSW |
12 |
103,571,228 (GRCm39) |
nonsense |
probably null |
|
|
R6386:Ppp4r4
|
UTSW |
12 |
103,559,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6712:Ppp4r4
|
UTSW |
12 |
103,562,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6755:Ppp4r4
|
UTSW |
12 |
103,551,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6868:Ppp4r4
|
UTSW |
12 |
103,557,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6879:Ppp4r4
|
UTSW |
12 |
103,518,179 (GRCm39) |
splice site |
probably null |
|
|
R7355:Ppp4r4
|
UTSW |
12 |
103,570,841 (GRCm39) |
nonsense |
probably null |
|
|
R7397:Ppp4r4
|
UTSW |
12 |
103,579,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7447:Ppp4r4
|
UTSW |
12 |
103,551,985 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7576:Ppp4r4
|
UTSW |
12 |
103,562,708 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7653:Ppp4r4
|
UTSW |
12 |
103,550,404 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7683:Ppp4r4
|
UTSW |
12 |
103,553,364 (GRCm39) |
nonsense |
probably null |
|
|
R7748:Ppp4r4
|
UTSW |
12 |
103,571,320 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7831:Ppp4r4
|
UTSW |
12 |
103,557,080 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7833:Ppp4r4
|
UTSW |
12 |
103,564,407 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8238:Ppp4r4
|
UTSW |
12 |
103,557,066 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8559:Ppp4r4
|
UTSW |
12 |
103,559,420 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8674:Ppp4r4
|
UTSW |
12 |
103,562,720 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8799:Ppp4r4
|
UTSW |
12 |
103,567,623 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8847:Ppp4r4
|
UTSW |
12 |
103,562,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8968:Ppp4r4
|
UTSW |
12 |
103,566,706 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9075:Ppp4r4
|
UTSW |
12 |
103,570,290 (GRCm39) |
nonsense |
probably null |
|
|
R9106:Ppp4r4
|
UTSW |
12 |
103,570,315 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9393:Ppp4r4
|
UTSW |
12 |
103,571,296 (GRCm39) |
nonsense |
probably null |
|
|
R9508:Ppp4r4
|
UTSW |
12 |
103,542,561 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9520:Ppp4r4
|
UTSW |
12 |
103,500,378 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9636:Ppp4r4
|
UTSW |
12 |
103,564,688 (GRCm39) |
missense |
unknown |
|
|
R9641:Ppp4r4
|
UTSW |
12 |
103,567,811 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9765:Ppp4r4
|
UTSW |
12 |
103,550,346 (GRCm39) |
nonsense |
probably null |
|
|
R9766:Ppp4r4
|
UTSW |
12 |
103,562,735 (GRCm39) |
missense |
probably benign |
0.40 |
|
X0025:Ppp4r4
|
UTSW |
12 |
103,566,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCAAAGTCACAGTTTCTGGTG -3'
(R):5'- TAAGTTCTCCTAAGGCTGCG -3'
Sequencing Primer
(F):5'- CAAAGTCACAGTTTCTGGTGATCTC -3'
(R):5'- TAAGGCTGCGCACACTTGAG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation