Incidental Mutation 'R2010:Rusc2'
| ID |
219443 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rusc2
|
| Ensembl Gene |
ENSMUSG00000035969 |
| Gene Name |
RUN and SH3 domain containing 2 |
| Synonyms |
|
| MMRRC Submission |
040019-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.158)
|
| Stock # |
R2010 (G1)
|
| Quality Score |
160 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
43381979-43427088 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 43415212 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 173
(P173S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000095710
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035645]
[ENSMUST00000098106]
[ENSMUST00000125399]
[ENSMUST00000131668]
[ENSMUST00000135216]
[ENSMUST00000136360]
[ENSMUST00000139198]
[ENSMUST00000144911]
[ENSMUST00000173682]
[ENSMUST00000152322]
[ENSMUST00000149221]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000035645
AA Change: P173S
PolyPhen 2
Score 0.057 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000038379
Gene: ENSMUSG00000035969
AA Change: P173S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
SH3
|
1457 |
1512 |
7.4e-11 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098106
AA Change: P173S
PolyPhen 2
Score 0.057 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000095710
Gene: ENSMUSG00000035969
AA Change: P173S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
SH3
|
1457 |
1512 |
7.4e-11 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125393
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125399
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131037
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131668
AA Change: P173S
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000118528
Gene: ENSMUSG00000035969
AA Change: P173S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135216
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000136360
|
| SMART Domains |
Protein: ENSMUSP00000123431
Gene: ENSMUSG00000035969
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139198
|
| SMART Domains |
Protein: ENSMUSP00000121528
Gene: ENSMUSG00000035969
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144911
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146710
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173682
AA Change: P173S
PolyPhen 2
Score 0.028 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000133715
Gene: ENSMUSG00000035969
AA Change: P173S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
703 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
740 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150066
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000149556
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152322
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149221
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 92.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810062G17Rik |
G |
A |
3: 36,481,806 (GRCm38) |
G74S |
unknown |
Het |
| 4930452B06Rik |
A |
T |
14: 8,511,021 (GRCm38) |
F464L |
probably damaging |
Het |
| 4932438A13Rik |
T |
G |
3: 36,928,551 (GRCm38) |
N788K |
probably benign |
Het |
| Aimp1 |
A |
T |
3: 132,667,492 (GRCm38) |
L229Q |
probably benign |
Het |
| Arhgef6 |
T |
C |
X: 57,299,505 (GRCm38) |
T52A |
possibly damaging |
Het |
| Aste1 |
C |
A |
9: 105,403,502 (GRCm38) |
H25Q |
probably damaging |
Het |
| Atp13a1 |
G |
A |
8: 69,791,360 (GRCm38) |
G36R |
possibly damaging |
Het |
| Bahcc1 |
T |
C |
11: 120,272,778 (GRCm38) |
V634A |
probably damaging |
Het |
| C1s1 |
A |
T |
6: 124,537,394 (GRCm38) |
Y168N |
probably damaging |
Het |
| Camsap2 |
T |
C |
1: 136,274,868 (GRCm38) |
S612G |
probably damaging |
Het |
| Cdh23 |
C |
A |
10: 60,314,227 (GRCm38) |
R2611L |
probably damaging |
Het |
| Cilp2 |
A |
G |
8: 69,881,694 (GRCm38) |
Y885H |
probably damaging |
Het |
| D430042O09Rik |
A |
G |
7: 125,872,956 (GRCm38) |
I1544M |
possibly damaging |
Het |
| Dhrs3 |
C |
T |
4: 144,927,188 (GRCm38) |
T227I |
possibly damaging |
Het |
| Dnah2 |
A |
T |
11: 69,458,358 (GRCm38) |
|
probably null |
Het |
| Dnah3 |
T |
G |
7: 120,095,177 (GRCm38) |
M1L |
probably benign |
Het |
| Ehbp1l1 |
A |
G |
19: 5,719,283 (GRCm38) |
I664T |
probably benign |
Het |
| Eif4e |
C |
T |
3: 138,555,458 (GRCm38) |
T171I |
probably benign |
Het |
| Elfn1 |
C |
T |
5: 139,973,316 (GRCm38) |
R692W |
probably damaging |
Het |
| Eps8l3 |
T |
A |
3: 107,879,372 (GRCm38) |
M1K |
probably null |
Het |
| Evi5 |
C |
A |
5: 107,813,545 (GRCm38) |
|
probably null |
Het |
| Fancd2 |
A |
T |
6: 113,593,291 (GRCm38) |
D1401V |
probably damaging |
Het |
| Fat2 |
G |
A |
11: 55,253,827 (GRCm38) |
R4074C |
probably damaging |
Het |
| Fkbp4 |
A |
T |
6: 128,435,802 (GRCm38) |
V55E |
probably benign |
Het |
| Fnip1 |
A |
G |
11: 54,482,503 (GRCm38) |
D180G |
probably damaging |
Het |
| Galc |
A |
G |
12: 98,254,230 (GRCm38) |
F126S |
possibly damaging |
Het |
| Gdf7 |
C |
T |
12: 8,301,729 (GRCm38) |
V69M |
unknown |
Het |
| Glis2 |
A |
G |
16: 4,608,711 (GRCm38) |
E22G |
probably damaging |
Het |
| Hist1h2bb |
G |
A |
13: 23,747,128 (GRCm38) |
V112M |
possibly damaging |
Het |
| Hps4 |
T |
A |
5: 112,369,476 (GRCm38) |
V243E |
probably damaging |
Het |
| Ighe |
T |
A |
12: 113,271,488 (GRCm38) |
I351F |
unknown |
Het |
| Irak4 |
A |
T |
15: 94,551,806 (GRCm38) |
R55S |
probably damaging |
Het |
| Itpr2 |
G |
A |
6: 146,227,524 (GRCm38) |
|
probably null |
Het |
| Kirrel3 |
T |
C |
9: 34,939,198 (GRCm38) |
Y41H |
probably damaging |
Het |
| Krr1 |
A |
G |
10: 111,975,569 (GRCm38) |
E56G |
possibly damaging |
Het |
| Lgi1 |
G |
A |
19: 38,301,235 (GRCm38) |
V250I |
probably damaging |
Het |
| Lipf |
A |
G |
19: 33,973,546 (GRCm38) |
N306D |
probably benign |
Het |
| Lman2l |
C |
T |
1: 36,445,181 (GRCm38) |
W18* |
probably null |
Het |
| Lztfl1 |
T |
A |
9: 123,702,186 (GRCm38) |
N239I |
possibly damaging |
Het |
| Mief1 |
T |
C |
15: 80,247,925 (GRCm38) |
S66P |
possibly damaging |
Het |
| Mmp8 |
C |
A |
9: 7,567,534 (GRCm38) |
S465* |
probably null |
Het |
| Muc2 |
A |
T |
7: 141,700,875 (GRCm38) |
T208S |
probably damaging |
Het |
| Myh8 |
A |
T |
11: 67,297,164 (GRCm38) |
K921* |
probably null |
Het |
| Myh9 |
T |
C |
15: 77,771,947 (GRCm38) |
E1121G |
probably benign |
Het |
| Nbn |
T |
C |
4: 15,969,393 (GRCm38) |
S213P |
probably damaging |
Het |
| Nol10 |
A |
G |
12: 17,416,101 (GRCm38) |
E499G |
probably benign |
Het |
| Nxn |
T |
C |
11: 76,398,801 (GRCm38) |
E87G |
probably damaging |
Het |
| Olfr293 |
A |
G |
7: 86,664,603 (GRCm38) |
T314A |
probably benign |
Het |
| Olfr568 |
T |
A |
7: 102,877,685 (GRCm38) |
C188* |
probably null |
Het |
| Olfr937 |
T |
C |
9: 39,060,099 (GRCm38) |
H189R |
probably benign |
Het |
| Pds5b |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
5: 150,775,354 (GRCm38) |
|
probably benign |
Het |
| Pigk |
A |
G |
3: 152,766,514 (GRCm38) |
I354M |
probably damaging |
Het |
| Pigl |
T |
A |
11: 62,458,682 (GRCm38) |
C75S |
probably damaging |
Het |
| Pm20d1 |
T |
A |
1: 131,812,114 (GRCm38) |
I400N |
probably benign |
Het |
| Prkg2 |
T |
A |
5: 99,024,805 (GRCm38) |
H17L |
probably benign |
Het |
| Psmd1 |
T |
A |
1: 86,075,997 (GRCm38) |
L168Q |
probably damaging |
Het |
| Rab3gap2 |
A |
T |
1: 185,278,281 (GRCm38) |
H1136L |
possibly damaging |
Het |
| Rb1 |
T |
C |
14: 73,294,993 (GRCm38) |
T134A |
probably benign |
Het |
| Rims1 |
T |
C |
1: 22,296,996 (GRCm38) |
E1024G |
probably damaging |
Het |
| Rrp12 |
A |
G |
19: 41,872,937 (GRCm38) |
V977A |
probably benign |
Het |
| Selenov |
A |
T |
7: 28,288,022 (GRCm38) |
D310E |
probably damaging |
Het |
| Serpina3f |
T |
A |
12: 104,217,323 (GRCm38) |
L148Q |
probably damaging |
Het |
| Slc10a1 |
C |
T |
12: 80,960,447 (GRCm38) |
V187I |
probably benign |
Het |
| Spsb2 |
A |
G |
6: 124,810,376 (GRCm38) |
K258E |
probably damaging |
Het |
| Tas2r105 |
A |
C |
6: 131,687,402 (GRCm38) |
V21G |
probably benign |
Het |
| Tmem229b-ps |
T |
A |
10: 53,475,199 (GRCm38) |
|
noncoding transcript |
Het |
| Tnrc6a |
C |
G |
7: 123,171,046 (GRCm38) |
H686Q |
probably benign |
Het |
| Trpc2 |
T |
A |
7: 102,094,573 (GRCm38) |
F715L |
probably benign |
Het |
| Ube2t |
T |
A |
1: 134,969,298 (GRCm38) |
I56N |
probably benign |
Het |
| Ubr4 |
T |
C |
4: 139,480,652 (GRCm38) |
Y4915H |
possibly damaging |
Het |
| Usp32 |
T |
A |
11: 85,040,004 (GRCm38) |
E533D |
probably damaging |
Het |
| Vipr2 |
T |
G |
12: 116,122,810 (GRCm38) |
|
probably null |
Het |
| Vmn1r15 |
A |
G |
6: 57,258,284 (GRCm38) |
T46A |
probably benign |
Het |
| Vmn1r203 |
T |
G |
13: 22,524,447 (GRCm38) |
S133A |
possibly damaging |
Het |
| Vmn1r215 |
T |
G |
13: 23,076,208 (GRCm38) |
N139K |
probably damaging |
Het |
| Vmn1r232 |
C |
T |
17: 20,913,339 (GRCm38) |
R333H |
probably benign |
Het |
| Wdr20rt |
C |
A |
12: 65,227,214 (GRCm38) |
H311N |
possibly damaging |
Het |
| Zranb1 |
T |
C |
7: 132,966,696 (GRCm38) |
|
probably null |
Het |
|
| Other mutations in Rusc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01358:Rusc2
|
APN |
4 |
43,426,116 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL01474:Rusc2
|
APN |
4 |
43,416,434 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01541:Rusc2
|
APN |
4 |
43,415,840 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL01628:Rusc2
|
APN |
4 |
43,425,729 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01969:Rusc2
|
APN |
4 |
43,415,738 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL02030:Rusc2
|
APN |
4 |
43,416,095 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02079:Rusc2
|
APN |
4 |
43,425,668 (GRCm38) |
missense |
probably benign |
|
|
IGL02115:Rusc2
|
APN |
4 |
43,426,136 (GRCm38) |
splice site |
probably benign |
|
|
IGL02122:Rusc2
|
APN |
4 |
43,421,685 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
IGL02350:Rusc2
|
APN |
4 |
43,425,351 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02357:Rusc2
|
APN |
4 |
43,425,351 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02437:Rusc2
|
APN |
4 |
43,415,545 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02930:Rusc2
|
APN |
4 |
43,416,376 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL03154:Rusc2
|
APN |
4 |
43,425,806 (GRCm38) |
missense |
probably benign |
0.00 |
|
P0026:Rusc2
|
UTSW |
4 |
43,415,840 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0036:Rusc2
|
UTSW |
4 |
43,424,009 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0068:Rusc2
|
UTSW |
4 |
43,424,100 (GRCm38) |
splice site |
probably benign |
|
|
R0068:Rusc2
|
UTSW |
4 |
43,424,100 (GRCm38) |
splice site |
probably benign |
|
|
R0114:Rusc2
|
UTSW |
4 |
43,422,055 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0255:Rusc2
|
UTSW |
4 |
43,423,954 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0471:Rusc2
|
UTSW |
4 |
43,425,486 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1381:Rusc2
|
UTSW |
4 |
43,416,137 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1413:Rusc2
|
UTSW |
4 |
43,416,568 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1416:Rusc2
|
UTSW |
4 |
43,421,617 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R1731:Rusc2
|
UTSW |
4 |
43,426,046 (GRCm38) |
missense |
probably benign |
|
|
R1864:Rusc2
|
UTSW |
4 |
43,421,719 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R1897:Rusc2
|
UTSW |
4 |
43,421,749 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2212:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2275:Rusc2
|
UTSW |
4 |
43,416,260 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2885:Rusc2
|
UTSW |
4 |
43,415,456 (GRCm38) |
missense |
probably benign |
0.28 |
|
R2886:Rusc2
|
UTSW |
4 |
43,415,456 (GRCm38) |
missense |
probably benign |
0.28 |
|
R3412:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3413:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3414:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3852:Rusc2
|
UTSW |
4 |
43,416,424 (GRCm38) |
missense |
probably benign |
0.45 |
|
R4135:Rusc2
|
UTSW |
4 |
43,425,563 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4272:Rusc2
|
UTSW |
4 |
43,415,533 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4574:Rusc2
|
UTSW |
4 |
43,416,080 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4888:Rusc2
|
UTSW |
4 |
43,423,942 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5010:Rusc2
|
UTSW |
4 |
43,415,926 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5071:Rusc2
|
UTSW |
4 |
43,415,240 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5131:Rusc2
|
UTSW |
4 |
43,414,948 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5177:Rusc2
|
UTSW |
4 |
43,421,805 (GRCm38) |
splice site |
probably null |
|
|
R5540:Rusc2
|
UTSW |
4 |
43,423,975 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5561:Rusc2
|
UTSW |
4 |
43,415,932 (GRCm38) |
nonsense |
probably null |
|
|
R5628:Rusc2
|
UTSW |
4 |
43,425,348 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5645:Rusc2
|
UTSW |
4 |
43,425,758 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6129:Rusc2
|
UTSW |
4 |
43,424,271 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6362:Rusc2
|
UTSW |
4 |
43,416,416 (GRCm38) |
missense |
probably benign |
0.30 |
|
R6633:Rusc2
|
UTSW |
4 |
43,414,852 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6980:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm38) |
missense |
probably benign |
0.35 |
|
R7491:Rusc2
|
UTSW |
4 |
43,426,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7641:Rusc2
|
UTSW |
4 |
43,425,335 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7698:Rusc2
|
UTSW |
4 |
43,414,900 (GRCm38) |
nonsense |
probably null |
|
|
R7710:Rusc2
|
UTSW |
4 |
43,416,119 (GRCm38) |
missense |
probably benign |
0.07 |
|
R8052:Rusc2
|
UTSW |
4 |
43,421,851 (GRCm38) |
missense |
probably benign |
|
|
R8061:Rusc2
|
UTSW |
4 |
43,422,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8127:Rusc2
|
UTSW |
4 |
43,423,747 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R8319:Rusc2
|
UTSW |
4 |
43,425,378 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8355:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm38) |
missense |
probably benign |
0.35 |
|
R8397:Rusc2
|
UTSW |
4 |
43,424,206 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8455:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm38) |
missense |
probably benign |
0.35 |
|
R8553:Rusc2
|
UTSW |
4 |
43,416,508 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8725:Rusc2
|
UTSW |
4 |
43,401,351 (GRCm38) |
intron |
probably benign |
|
|
R8725:Rusc2
|
UTSW |
4 |
43,415,396 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8727:Rusc2
|
UTSW |
4 |
43,401,351 (GRCm38) |
intron |
probably benign |
|
|
R8834:Rusc2
|
UTSW |
4 |
43,416,431 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9295:Rusc2
|
UTSW |
4 |
43,416,382 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9483:Rusc2
|
UTSW |
4 |
43,415,897 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9666:Rusc2
|
UTSW |
4 |
43,416,262 (GRCm38) |
missense |
probably benign |
0.21 |
|
R9705:Rusc2
|
UTSW |
4 |
43,424,936 (GRCm38) |
missense |
probably benign |
0.00 |
|
X0025:Rusc2
|
UTSW |
4 |
43,422,226 (GRCm38) |
missense |
probably benign |
0.00 |
|
X0066:Rusc2
|
UTSW |
4 |
43,422,204 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ATCCCTTCTTGGTGCAGGAAG -3'
(R):5'- GATTCGTCGGAACTGATCTTCCAC -3'
Sequencing Primer
(F):5'- GGTGTGGGTGAGACAGGACTC -3'
(R):5'- TCTTCCACTCTTGCTCAAAGGAAAAG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation