Incidental Mutation 'R1969:Thada'
| ID |
219581 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
039982-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1969 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 84617470 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Threonine
at position 1349
(P1349T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047524
AA Change: P1349T
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: P1349T
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Meta Mutation Damage Score |
0.2332 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110059E24Rik |
T |
C |
19: 21,575,609 (GRCm39) |
|
probably benign |
Het |
| Apoh |
G |
A |
11: 108,298,288 (GRCm39) |
R196Q |
probably benign |
Het |
| Arnt |
C |
T |
3: 95,355,704 (GRCm39) |
S16L |
possibly damaging |
Het |
| B4galnt4 |
T |
C |
7: 140,644,761 (GRCm39) |
F194L |
probably benign |
Het |
| BC034090 |
A |
T |
1: 155,100,972 (GRCm39) |
L431M |
possibly damaging |
Het |
| Bdh2 |
G |
T |
3: 134,994,040 (GRCm39) |
A31S |
probably damaging |
Het |
| Brd10 |
C |
T |
19: 29,694,075 (GRCm39) |
S1873N |
possibly damaging |
Het |
| Cacna1s |
T |
C |
1: 136,046,833 (GRCm39) |
S1821P |
probably benign |
Het |
| Caskin1 |
A |
T |
17: 24,725,824 (GRCm39) |
Q1370L |
possibly damaging |
Het |
| Ccdc83 |
T |
A |
7: 89,893,362 (GRCm39) |
S132C |
probably damaging |
Het |
| Cdk15 |
A |
T |
1: 59,370,110 (GRCm39) |
H384L |
probably damaging |
Het |
| Col24a1 |
T |
C |
3: 145,020,691 (GRCm39) |
I354T |
probably benign |
Het |
| Coro7 |
T |
C |
16: 4,451,620 (GRCm39) |
I451V |
probably benign |
Het |
| Ctnna2 |
T |
C |
6: 77,735,483 (GRCm39) |
E65G |
probably damaging |
Het |
| Ctsll3 |
A |
T |
13: 60,948,162 (GRCm39) |
W172R |
probably benign |
Het |
| D630045J12Rik |
T |
C |
6: 38,145,078 (GRCm39) |
D1316G |
probably damaging |
Het |
| Ddx19b |
C |
T |
8: 111,734,890 (GRCm39) |
A493T |
probably benign |
Het |
| Ddx4 |
C |
T |
13: 112,736,547 (GRCm39) |
V608I |
probably damaging |
Het |
| Ddx4 |
T |
A |
13: 112,757,276 (GRCm39) |
H348L |
probably damaging |
Het |
| Dnah17 |
G |
C |
11: 117,995,361 (GRCm39) |
Q996E |
probably benign |
Het |
| Dnah9 |
G |
C |
11: 65,739,197 (GRCm39) |
N4180K |
probably damaging |
Het |
| Dok7 |
A |
G |
5: 35,234,610 (GRCm39) |
|
probably null |
Het |
| Dpf3 |
T |
A |
12: 83,371,809 (GRCm39) |
|
probably null |
Het |
| Efcab3 |
A |
G |
11: 104,637,090 (GRCm39) |
I988M |
probably damaging |
Het |
| Elfn1 |
G |
C |
5: 139,958,604 (GRCm39) |
R536P |
probably damaging |
Het |
| Eml6 |
A |
G |
11: 29,783,075 (GRCm39) |
V602A |
probably benign |
Het |
| Enpp2 |
T |
C |
15: 54,746,378 (GRCm39) |
D296G |
probably damaging |
Het |
| Evi5 |
A |
T |
5: 107,896,230 (GRCm39) |
F738I |
probably benign |
Het |
| Eya2 |
T |
C |
2: 165,558,039 (GRCm39) |
S212P |
probably benign |
Het |
| Fam83a |
T |
C |
15: 57,849,498 (GRCm39) |
L14P |
probably damaging |
Het |
| Fanca |
A |
T |
8: 124,014,803 (GRCm39) |
M735K |
probably benign |
Het |
| Fancm |
T |
A |
12: 65,148,466 (GRCm39) |
S694T |
probably benign |
Het |
| Fibcd1 |
G |
A |
2: 31,706,673 (GRCm39) |
T386I |
probably damaging |
Het |
| Foxd4 |
A |
G |
19: 24,877,178 (GRCm39) |
S341P |
probably benign |
Het |
| Foxp4 |
C |
T |
17: 48,186,796 (GRCm39) |
R378Q |
unknown |
Het |
| Fryl |
A |
T |
5: 73,255,609 (GRCm39) |
S807R |
probably benign |
Het |
| Fscb |
T |
C |
12: 64,520,008 (GRCm39) |
E486G |
unknown |
Het |
| Galnt17 |
A |
G |
5: 131,179,782 (GRCm39) |
S122P |
probably benign |
Het |
| Ghitm |
A |
G |
14: 36,853,586 (GRCm39) |
F85L |
probably benign |
Het |
| Ghrh |
C |
A |
2: 157,175,386 (GRCm39) |
V32L |
probably benign |
Het |
| Gli2 |
C |
T |
1: 118,765,430 (GRCm39) |
R907H |
probably benign |
Het |
| Gm28042 |
A |
G |
2: 119,872,096 (GRCm39) |
*1015W |
probably null |
Het |
| Gpr179 |
T |
C |
11: 97,228,784 (GRCm39) |
T1124A |
probably benign |
Het |
| Grid2 |
C |
A |
6: 63,885,902 (GRCm39) |
C99* |
probably null |
Het |
| Grin1 |
A |
T |
2: 25,187,927 (GRCm39) |
M523K |
probably benign |
Het |
| Gucy2g |
T |
C |
19: 55,211,328 (GRCm39) |
Y634C |
possibly damaging |
Het |
| Gucy2g |
T |
G |
19: 55,221,485 (GRCm39) |
T339P |
probably benign |
Het |
| Haus6 |
A |
T |
4: 86,522,483 (GRCm39) |
L116H |
probably damaging |
Het |
| Hey1 |
T |
C |
3: 8,731,879 (GRCm39) |
T18A |
probably benign |
Het |
| Hipk3 |
T |
C |
2: 104,264,186 (GRCm39) |
N792D |
probably damaging |
Het |
| Il19 |
A |
T |
1: 130,866,893 (GRCm39) |
L29Q |
probably damaging |
Het |
| Il21r |
A |
G |
7: 125,228,144 (GRCm39) |
Q205R |
probably damaging |
Het |
| Kcnip2 |
T |
C |
19: 45,782,122 (GRCm39) |
D169G |
probably null |
Het |
| Kctd18 |
T |
C |
1: 58,006,779 (GRCm39) |
I24V |
probably benign |
Het |
| Lcp1 |
T |
C |
14: 75,437,946 (GRCm39) |
S119P |
probably damaging |
Het |
| Lig3 |
G |
C |
11: 82,686,544 (GRCm39) |
D642H |
probably benign |
Het |
| Lrba |
A |
G |
3: 86,515,696 (GRCm39) |
K2166E |
probably damaging |
Het |
| Lrrn2 |
T |
C |
1: 132,866,972 (GRCm39) |
V679A |
probably benign |
Het |
| Lyst |
G |
A |
13: 13,904,929 (GRCm39) |
R3202H |
probably damaging |
Het |
| Micall2 |
A |
G |
5: 139,721,885 (GRCm39) |
C11R |
probably damaging |
Het |
| Morc2b |
T |
G |
17: 33,356,065 (GRCm39) |
Q569P |
probably benign |
Het |
| Mtrf1 |
A |
G |
14: 79,639,111 (GRCm39) |
E81G |
probably damaging |
Het |
| Myh2 |
G |
T |
11: 67,080,004 (GRCm39) |
S1099I |
possibly damaging |
Het |
| Nap1l1 |
T |
A |
10: 111,326,914 (GRCm39) |
D158E |
probably benign |
Het |
| Nckap5l |
T |
A |
15: 99,320,699 (GRCm39) |
T1285S |
probably damaging |
Het |
| Nsrp1 |
A |
T |
11: 76,936,612 (GRCm39) |
M528K |
probably damaging |
Het |
| Numa1 |
C |
T |
7: 101,658,529 (GRCm39) |
A1605V |
probably damaging |
Het |
| Nutm2 |
T |
C |
13: 50,627,878 (GRCm39) |
L453P |
probably damaging |
Het |
| Ofd1 |
T |
C |
X: 165,210,210 (GRCm39) |
Y205C |
probably benign |
Het |
| Or2ag12 |
T |
A |
7: 106,276,877 (GRCm39) |
N272I |
probably damaging |
Het |
| Or2n1c |
A |
G |
17: 38,519,355 (GRCm39) |
Y73C |
probably damaging |
Het |
| Or4c125 |
T |
A |
2: 89,170,640 (GRCm39) |
N2I |
probably damaging |
Het |
| Or52k2 |
A |
T |
7: 102,253,777 (GRCm39) |
D72V |
probably damaging |
Het |
| Or7a40 |
T |
A |
16: 16,491,447 (GRCm39) |
M133L |
probably benign |
Het |
| Patl1 |
T |
C |
19: 11,898,782 (GRCm39) |
L159P |
probably benign |
Het |
| Paxip1 |
G |
A |
5: 27,949,134 (GRCm39) |
T1045I |
probably damaging |
Het |
| Phaf1 |
T |
A |
8: 105,973,132 (GRCm39) |
D247E |
possibly damaging |
Het |
| Pik3ca |
A |
G |
3: 32,505,903 (GRCm39) |
|
probably null |
Het |
| Pkhd1 |
T |
A |
1: 20,451,747 (GRCm39) |
I2183F |
probably damaging |
Het |
| Plec |
C |
T |
15: 76,073,372 (GRCm39) |
R319H |
probably damaging |
Het |
| Pnkd |
G |
A |
1: 74,391,008 (GRCm39) |
G334D |
probably damaging |
Het |
| Prss50 |
A |
G |
9: 110,691,449 (GRCm39) |
Y251C |
probably damaging |
Het |
| Rab11b |
A |
T |
17: 33,979,209 (GRCm39) |
Y10N |
probably damaging |
Het |
| Rfc1 |
G |
A |
5: 65,476,867 (GRCm39) |
R4W |
probably damaging |
Het |
| Rgs19 |
A |
T |
2: 181,331,276 (GRCm39) |
F119Y |
probably damaging |
Het |
| Safb |
A |
G |
17: 56,912,821 (GRCm39) |
H883R |
probably benign |
Het |
| Serpine1 |
G |
A |
5: 137,096,601 (GRCm39) |
Q227* |
probably null |
Het |
| Slc25a13 |
A |
G |
6: 6,096,668 (GRCm39) |
|
probably null |
Het |
| Slc6a18 |
T |
A |
13: 73,812,308 (GRCm39) |
T502S |
possibly damaging |
Het |
| Sox4 |
T |
C |
13: 29,136,631 (GRCm39) |
D125G |
probably damaging |
Het |
| Spata31d1e |
T |
C |
13: 59,890,599 (GRCm39) |
D407G |
probably damaging |
Het |
| Stag3 |
C |
T |
5: 138,298,400 (GRCm39) |
T731I |
probably damaging |
Het |
| Tmem245 |
C |
A |
4: 56,937,964 (GRCm39) |
V195F |
probably benign |
Het |
| Tnxb |
A |
G |
17: 34,898,055 (GRCm39) |
H901R |
probably benign |
Het |
| Trim39 |
A |
T |
17: 36,579,645 (GRCm39) |
D103E |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,562,304 (GRCm39) |
V28847E |
probably damaging |
Het |
| Tubb1 |
A |
T |
2: 174,297,484 (GRCm39) |
D31V |
possibly damaging |
Het |
| Ush1g |
A |
G |
11: 115,209,280 (GRCm39) |
S305P |
probably damaging |
Het |
| Vmn1r191 |
A |
T |
13: 22,362,952 (GRCm39) |
N267K |
possibly damaging |
Het |
| Vmn1r59 |
A |
T |
7: 5,457,038 (GRCm39) |
Y241N |
probably damaging |
Het |
| Vmn2r49 |
T |
C |
7: 9,720,235 (GRCm39) |
N419D |
probably damaging |
Het |
| Vps35 |
T |
C |
8: 86,005,623 (GRCm39) |
D326G |
possibly damaging |
Het |
| Xdh |
A |
G |
17: 74,199,746 (GRCm39) |
S1187P |
possibly damaging |
Het |
| Xpc |
A |
C |
6: 91,478,007 (GRCm39) |
|
probably null |
Het |
| Zfp273 |
T |
C |
13: 67,973,282 (GRCm39) |
Y104H |
probably damaging |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,723,731 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,533,432 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,766,283 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,751,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,533,469 (GRCm39) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,736,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAAGTCACACAGAGCTGTTGTAC -3'
(R):5'- TCAAGTCAGTTTTGCTATCACCTG -3'
Sequencing Primer
(F):5'- GTACTTACTTGCAGAAGTGTCCCATG -3'
(R):5'- AGTCAGTTTTGCTATCACCTGTTATC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation