Incidental Mutation 'R1970:Ddx60'
| ID |
219719 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| Synonyms |
|
| MMRRC Submission |
039983-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.145)
|
| Stock # |
R1970 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
61928087-62038244 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 61972206 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 676
(H676L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000070631
AA Change: H675L
PolyPhen 2
Score 0.693 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
AA Change: H675L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000093485
AA Change: H676L
PolyPhen 2
Score 0.934 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
AA Change: H676L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Meta Mutation Damage Score |
0.2040 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.2%
|
| Validation Efficiency |
97% (121/125) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 121 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca17 |
A |
T |
17: 24,307,575 (GRCm38) |
H578Q |
probably benign |
Het |
| Abcc12 |
A |
G |
8: 86,527,281 (GRCm38) |
I958T |
probably benign |
Het |
| Abcg5 |
AATCATTTG |
AG |
17: 84,673,602 (GRCm38) |
|
probably null |
Het |
| Acap2 |
A |
G |
16: 31,133,527 (GRCm38) |
|
probably null |
Het |
| Adgrb1 |
T |
C |
15: 74,539,877 (GRCm38) |
|
probably benign |
Het |
| Akap6 |
T |
A |
12: 52,938,475 (GRCm38) |
V897E |
probably damaging |
Het |
| Als2 |
A |
T |
1: 59,215,169 (GRCm38) |
L343Q |
probably benign |
Het |
| Arhgap5 |
A |
G |
12: 52,542,593 (GRCm38) |
I1275M |
probably damaging |
Het |
| Arnt |
C |
T |
3: 95,448,393 (GRCm38) |
S16L |
possibly damaging |
Het |
| Bglap3 |
C |
T |
3: 88,376,993 (GRCm38) |
|
probably benign |
Het |
| Blnk |
T |
C |
19: 40,940,165 (GRCm38) |
|
probably benign |
Het |
| C1qtnf4 |
T |
C |
2: 90,889,659 (GRCm38) |
M92T |
probably damaging |
Het |
| C77080 |
A |
G |
4: 129,226,017 (GRCm38) |
|
probably benign |
Het |
| Ccdc177 |
G |
A |
12: 80,758,712 (GRCm38) |
R263C |
unknown |
Het |
| Ccdc83 |
T |
A |
7: 90,244,154 (GRCm38) |
S132C |
probably damaging |
Het |
| Cdc7 |
A |
G |
5: 106,973,074 (GRCm38) |
|
probably benign |
Het |
| Cgnl1 |
T |
A |
9: 71,725,535 (GRCm38) |
N178I |
probably benign |
Het |
| Col27a1 |
C |
T |
4: 63,273,117 (GRCm38) |
|
probably benign |
Het |
| Col5a1 |
A |
T |
2: 27,986,754 (GRCm38) |
M822L |
unknown |
Het |
| Coro7 |
T |
C |
16: 4,633,756 (GRCm38) |
I451V |
probably benign |
Het |
| Csmd3 |
T |
C |
15: 48,673,531 (GRCm38) |
T92A |
probably damaging |
Het |
| Ddc |
A |
G |
11: 11,815,292 (GRCm38) |
V460A |
possibly damaging |
Het |
| Ddx4 |
C |
T |
13: 112,600,013 (GRCm38) |
V608I |
probably damaging |
Het |
| Dmtf1 |
T |
C |
5: 9,148,989 (GRCm38) |
E48G |
probably benign |
Het |
| Dpf3 |
T |
A |
12: 83,325,035 (GRCm38) |
|
probably null |
Het |
| Dydc2 |
A |
G |
14: 41,061,903 (GRCm38) |
C88R |
probably benign |
Het |
| Elovl4 |
A |
G |
9: 83,780,719 (GRCm38) |
Y163H |
probably damaging |
Het |
| Enpp2 |
T |
C |
15: 54,882,982 (GRCm38) |
D296G |
probably damaging |
Het |
| Fam83h |
G |
T |
15: 76,006,570 (GRCm38) |
|
probably benign |
Het |
| Fbf1 |
T |
A |
11: 116,151,491 (GRCm38) |
Q511L |
possibly damaging |
Het |
| Fhdc1 |
A |
T |
3: 84,454,851 (GRCm38) |
L323Q |
probably damaging |
Het |
| Fmnl2 |
T |
A |
2: 53,105,576 (GRCm38) |
V437D |
possibly damaging |
Het |
| Foxo3 |
A |
G |
10: 42,197,262 (GRCm38) |
S420P |
probably benign |
Het |
| Foxp4 |
C |
T |
17: 47,875,871 (GRCm38) |
R378Q |
unknown |
Het |
| Garem2 |
G |
T |
5: 30,117,174 (GRCm38) |
G844* |
probably null |
Het |
| Glmp |
T |
C |
3: 88,327,870 (GRCm38) |
L269S |
probably damaging |
Het |
| Gm2000 |
T |
G |
1: 156,366,447 (GRCm38) |
*124G |
probably null |
Het |
| Gm9915 |
T |
C |
1: 42,230,721 (GRCm38) |
|
noncoding transcript |
Het |
| Gnb4 |
A |
T |
3: 32,598,141 (GRCm38) |
D27E |
probably damaging |
Het |
| Gnb5 |
A |
G |
9: 75,344,650 (GRCm38) |
|
probably null |
Het |
| Gpr161 |
T |
G |
1: 165,306,358 (GRCm38) |
V63G |
probably damaging |
Het |
| Gsk3a |
T |
A |
7: 25,229,721 (GRCm38) |
|
probably benign |
Het |
| Hapln2 |
T |
C |
3: 88,024,120 (GRCm38) |
|
probably null |
Het |
| Incenp |
G |
T |
19: 9,885,487 (GRCm38) |
T401N |
unknown |
Het |
| Kalrn |
A |
G |
16: 33,977,524 (GRCm38) |
|
probably null |
Het |
| Kcnq3 |
A |
G |
15: 66,028,623 (GRCm38) |
|
probably null |
Het |
| Kif21b |
T |
C |
1: 136,171,156 (GRCm38) |
V1394A |
probably damaging |
Het |
| Klhl23 |
T |
C |
2: 69,833,686 (GRCm38) |
C460R |
probably damaging |
Het |
| L3mbtl1 |
G |
A |
2: 162,959,572 (GRCm38) |
A291T |
probably damaging |
Het |
| Lcp1 |
T |
C |
14: 75,200,506 (GRCm38) |
S119P |
probably damaging |
Het |
| Ldhc |
A |
G |
7: 46,869,751 (GRCm38) |
I133V |
probably benign |
Het |
| Lmntd2 |
G |
A |
7: 141,212,059 (GRCm38) |
|
probably benign |
Het |
| Lpl |
A |
T |
8: 68,896,802 (GRCm38) |
K327* |
probably null |
Het |
| Lrp1b |
T |
C |
2: 40,875,069 (GRCm38) |
D2801G |
probably damaging |
Het |
| Mppe1 |
C |
A |
18: 67,229,772 (GRCm38) |
A131S |
probably benign |
Het |
| Msh3 |
T |
A |
13: 92,249,820 (GRCm38) |
|
probably benign |
Het |
| Msh5 |
A |
G |
17: 35,033,600 (GRCm38) |
I377T |
probably damaging |
Het |
| Myo1e |
T |
C |
9: 70,368,773 (GRCm38) |
F757L |
probably benign |
Het |
| Myof |
A |
T |
19: 37,945,634 (GRCm38) |
D955E |
probably damaging |
Het |
| Nckap1 |
C |
T |
2: 80,517,942 (GRCm38) |
S889N |
probably benign |
Het |
| Ncor2 |
T |
C |
5: 125,038,918 (GRCm38) |
D858G |
probably damaging |
Het |
| Neb |
A |
T |
2: 52,263,905 (GRCm38) |
V2398D |
possibly damaging |
Het |
| Nefl |
C |
G |
14: 68,086,672 (GRCm38) |
T453R |
probably benign |
Het |
| Nf1 |
A |
G |
11: 79,553,961 (GRCm38) |
N371D |
probably benign |
Het |
| Nlrp4f |
T |
C |
13: 65,194,091 (GRCm38) |
Y580C |
probably damaging |
Het |
| Nme8 |
A |
C |
13: 19,652,322 (GRCm38) |
L228R |
probably damaging |
Het |
| Numa1 |
C |
T |
7: 102,009,322 (GRCm38) |
A1605V |
probably damaging |
Het |
| Ofd1 |
T |
C |
X: 166,427,214 (GRCm38) |
Y205C |
probably benign |
Het |
| Olfr1047 |
T |
A |
2: 86,228,252 (GRCm38) |
T240S |
probably damaging |
Het |
| Olfr1283 |
C |
T |
2: 111,369,076 (GRCm38) |
S148L |
probably benign |
Het |
| Olfr1532-ps1 |
G |
A |
7: 106,914,246 (GRCm38) |
G16D |
probably damaging |
Het |
| Olfr693 |
T |
A |
7: 106,677,670 (GRCm38) |
N272I |
probably damaging |
Het |
| Olfr972 |
T |
A |
9: 39,873,938 (GRCm38) |
I221N |
probably damaging |
Het |
| Pclo |
A |
G |
5: 14,713,473 (GRCm38) |
T3987A |
unknown |
Het |
| Pdgfrb |
G |
A |
18: 61,066,494 (GRCm38) |
|
probably benign |
Het |
| Pdxk |
G |
A |
10: 78,441,154 (GRCm38) |
T270I |
probably damaging |
Het |
| Pex5 |
T |
C |
6: 124,414,405 (GRCm38) |
E10G |
probably damaging |
Het |
| Pik3c2g |
T |
A |
6: 139,900,386 (GRCm38) |
|
probably null |
Het |
| Pkhd1 |
T |
A |
1: 20,381,523 (GRCm38) |
I2183F |
probably damaging |
Het |
| Plppr2 |
T |
C |
9: 21,941,126 (GRCm38) |
V102A |
probably damaging |
Het |
| Plxnd1 |
T |
C |
6: 115,962,517 (GRCm38) |
T1449A |
probably damaging |
Het |
| Pnkd |
T |
A |
1: 74,285,910 (GRCm38) |
|
probably null |
Het |
| Pom121l2 |
A |
G |
13: 21,983,472 (GRCm38) |
I638V |
probably damaging |
Het |
| Prag1 |
A |
G |
8: 36,129,160 (GRCm38) |
|
probably null |
Het |
| Ranbp10 |
A |
G |
8: 105,786,708 (GRCm38) |
F191L |
probably damaging |
Het |
| Rapgef1 |
T |
C |
2: 29,733,711 (GRCm38) |
L824P |
probably damaging |
Het |
| Rec8 |
T |
C |
14: 55,624,142 (GRCm38) |
L418P |
probably damaging |
Het |
| Rimbp2 |
T |
A |
5: 128,797,241 (GRCm38) |
N429Y |
probably damaging |
Het |
| Rpe65 |
C |
A |
3: 159,615,670 (GRCm38) |
T373K |
probably benign |
Het |
| Rrn3 |
T |
C |
16: 13,789,074 (GRCm38) |
S151P |
probably damaging |
Het |
| Scn7a |
A |
G |
2: 66,684,289 (GRCm38) |
V1047A |
possibly damaging |
Het |
| Scn9a |
G |
T |
2: 66,515,380 (GRCm38) |
P1123Q |
probably damaging |
Het |
| Secisbp2l |
T |
C |
2: 125,747,510 (GRCm38) |
D706G |
probably damaging |
Het |
| Serpina5 |
A |
T |
12: 104,103,857 (GRCm38) |
T338S |
probably benign |
Het |
| Sez6 |
G |
A |
11: 77,954,068 (GRCm38) |
|
probably null |
Het |
| Shisa4 |
C |
T |
1: 135,372,274 (GRCm38) |
G157D |
probably damaging |
Het |
| Slc1a7 |
G |
T |
4: 107,968,585 (GRCm38) |
D14Y |
probably benign |
Het |
| Slc25a11 |
A |
C |
11: 70,646,173 (GRCm38) |
L51V |
probably benign |
Het |
| Slit3 |
A |
G |
11: 35,630,841 (GRCm38) |
|
probably null |
Het |
| Spata13 |
G |
T |
14: 60,691,463 (GRCm38) |
G157W |
probably damaging |
Het |
| Spta1 |
T |
C |
1: 174,240,367 (GRCm38) |
V2120A |
possibly damaging |
Het |
| Srpr |
T |
C |
9: 35,213,538 (GRCm38) |
|
probably null |
Het |
| Syt6 |
A |
G |
3: 103,587,420 (GRCm38) |
I234V |
probably benign |
Het |
| Thada |
G |
T |
17: 84,310,042 (GRCm38) |
P1349T |
probably damaging |
Het |
| Tmem161a |
C |
T |
8: 70,176,909 (GRCm38) |
R58W |
probably damaging |
Het |
| Top3b |
A |
G |
16: 16,883,519 (GRCm38) |
I232V |
probably damaging |
Het |
| Tspan1 |
T |
A |
4: 116,163,629 (GRCm38) |
Q197L |
possibly damaging |
Het |
| Ttc28 |
A |
C |
5: 111,235,635 (GRCm38) |
Y1334S |
probably benign |
Het |
| Ubxn6 |
G |
T |
17: 56,073,077 (GRCm38) |
N28K |
possibly damaging |
Het |
| Uggt1 |
T |
C |
1: 36,151,781 (GRCm38) |
D1366G |
probably damaging |
Het |
| Ugp2 |
A |
G |
11: 21,328,942 (GRCm38) |
S415P |
probably damaging |
Het |
| Vcan |
A |
T |
13: 89,689,038 (GRCm38) |
S2796T |
probably damaging |
Het |
| Vipr2 |
T |
C |
12: 116,136,206 (GRCm38) |
V231A |
probably benign |
Het |
| Vmn1r176 |
T |
C |
7: 23,834,948 (GRCm38) |
N260S |
probably benign |
Het |
| Vmn1r59 |
A |
T |
7: 5,454,039 (GRCm38) |
Y241N |
probably damaging |
Het |
| Vmn2r67 |
A |
T |
7: 85,151,805 (GRCm38) |
Y308N |
probably benign |
Het |
| Vmn2r75 |
A |
T |
7: 86,148,262 (GRCm38) |
M781K |
probably damaging |
Het |
| Vwa3a |
A |
T |
7: 120,780,171 (GRCm38) |
I500F |
probably damaging |
Het |
| Zfp609 |
A |
G |
9: 65,795,277 (GRCm38) |
V31A |
probably damaging |
Het |
| Zfp689 |
G |
T |
7: 127,444,787 (GRCm38) |
Q224K |
probably damaging |
Het |
| Zfp81 |
A |
T |
17: 33,335,501 (GRCm38) |
L113H |
probably benign |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
61,958,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
61,987,431 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
61,969,583 (GRCm38) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
61,942,514 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
61,982,526 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
61,963,740 (GRCm38) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
61,983,865 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,017,823 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,000,709 (GRCm38) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,017,247 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
61,975,832 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
61,958,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,024,951 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
61,942,436 (GRCm38) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
61,984,115 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
61,988,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
61,979,341 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
61,956,122 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
61,988,083 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,012,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
61,977,882 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
61,958,113 (GRCm38) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
61,972,254 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
61,942,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,033,493 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0325:Ddx60
|
UTSW |
8 |
61,983,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0367:Ddx60
|
UTSW |
8 |
62,017,749 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R0403:Ddx60
|
UTSW |
8 |
61,994,541 (GRCm38) |
splice site |
probably benign |
|
|
R0479:Ddx60
|
UTSW |
8 |
61,969,657 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,017,794 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
61,987,361 (GRCm38) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
61,942,544 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
61,958,159 (GRCm38) |
splice site |
probably benign |
|
|
R1778:Ddx60
|
UTSW |
8 |
61,974,176 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1840:Ddx60
|
UTSW |
8 |
61,969,553 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1964:Ddx60
|
UTSW |
8 |
61,948,869 (GRCm38) |
missense |
probably benign |
0.10 |
|
R2101:Ddx60
|
UTSW |
8 |
61,940,645 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,017,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
61,956,141 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
61,958,063 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,037,091 (GRCm38) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,012,436 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,037,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
61,956,144 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
61,972,220 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
61,994,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
61,948,978 (GRCm38) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
61,942,461 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
61,987,421 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,023,261 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,012,424 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
61,945,906 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
61,974,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
61,984,158 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,010,002 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
61,950,451 (GRCm38) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
61,958,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,000,578 (GRCm38) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
61,948,921 (GRCm38) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
61,948,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,012,388 (GRCm38) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
61,963,722 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
61,940,740 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,021,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,000,582 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,023,241 (GRCm38) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
61,945,940 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
61,950,578 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
61,983,905 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
61,998,681 (GRCm38) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
61,977,950 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
61,956,239 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
61,983,890 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,000,689 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,037,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
61,988,108 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
61,958,578 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
61,940,674 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
61,975,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
61,977,890 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,017,171 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,017,250 (GRCm38) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
61,977,968 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
61,998,769 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
61,942,635 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
61,974,171 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
61,956,243 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
61,974,150 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
61,958,606 (GRCm38) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
61,945,956 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
61,940,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
61,994,519 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
61,974,134 (GRCm38) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
61,989,864 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,017,841 (GRCm38) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
61,977,978 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,009,960 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
61,972,214 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,012,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,033,417 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
61,963,692 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,000,588 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGTGAGTAAGAGAGTAAGTGTC -3'
(R):5'- TGCAAACACAGCTCTTTTAGAAT -3'
Sequencing Primer
(F):5'- TGAGTAAGAGAGTAAGTGTCATGAAG -3'
(R):5'- TCCCCAAGAGAAGGTTGGTC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation