Incidental Mutation 'R1982:Crybg3'
| ID |
220023 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Crybg3
|
| Ensembl Gene |
ENSMUSG00000022723 |
| Gene Name |
beta-gamma crystallin domain containing 3 |
| Synonyms |
Gm9581 |
| MMRRC Submission |
039994-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.138)
|
| Stock # |
R1982 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
59312451-59421410 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 59364488 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 2378
(D2378G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156047
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044604]
[ENSMUST00000139989]
[ENSMUST00000172910]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000044604
AA Change: D664G
PolyPhen 2
Score 0.205 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000037682
Gene: ENSMUSG00000022723
AA Change: D664G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
258 |
273 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
290 |
N/A |
INTRINSIC |
|
XTALbg
|
430 |
516 |
2.78e-4 |
SMART |
|
Pfam:Crystall
|
536 |
599 |
3.3e-7 |
PFAM |
|
XTALbg
|
614 |
699 |
1.2e-21 |
SMART |
|
XTALbg
|
707 |
790 |
5.73e-19 |
SMART |
|
XTALbg
|
803 |
881 |
6.87e-5 |
SMART |
|
XTALbg
|
889 |
969 |
1.28e-7 |
SMART |
|
RICIN
|
972 |
1104 |
8.16e-14 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129350
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139989
|
| SMART Domains |
Protein: ENSMUSP00000122663
Gene: ENSMUSG00000022723
| Domain | Start | End | E-Value | Type |
|---|
|
XTALbg
|
1 |
86 |
2.15e-3 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000172910
AA Change: D2378G
PolyPhen 2
Score 0.851 (Sensitivity: 0.83; Specificity: 0.93)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000179383
AA Change: D664G
PolyPhen 2
Score 0.205 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000137452
Gene: ENSMUSG00000022723
AA Change: D664G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
390 |
405 |
N/A |
INTRINSIC |
|
low complexity region
|
414 |
422 |
N/A |
INTRINSIC |
|
XTALbg
|
562 |
648 |
2.78e-4 |
SMART |
|
Pfam:Crystall
|
668 |
731 |
1e-6 |
PFAM |
|
XTALbg
|
746 |
831 |
1.2e-21 |
SMART |
|
XTALbg
|
839 |
922 |
5.73e-19 |
SMART |
|
XTALbg
|
935 |
1013 |
6.87e-5 |
SMART |
|
XTALbg
|
1021 |
1101 |
1.28e-7 |
SMART |
|
RICIN
|
1104 |
1236 |
8.16e-14 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatk |
G |
T |
11: 119,904,340 (GRCm39) |
P252Q |
probably damaging |
Het |
| Adamts4 |
T |
C |
1: 171,086,503 (GRCm39) |
V765A |
probably benign |
Het |
| Agfg2 |
A |
T |
5: 137,662,515 (GRCm39) |
V184E |
possibly damaging |
Het |
| Alas1 |
A |
T |
9: 106,115,384 (GRCm39) |
I48N |
probably damaging |
Het |
| Anks1 |
T |
C |
17: 28,204,095 (GRCm39) |
V181A |
probably damaging |
Het |
| Anxa8 |
A |
T |
14: 33,818,527 (GRCm39) |
R261S |
probably damaging |
Het |
| Aqp4 |
T |
C |
18: 15,526,608 (GRCm39) |
D291G |
probably damaging |
Het |
| Atrn |
A |
G |
2: 130,812,142 (GRCm39) |
R696G |
probably benign |
Het |
| Barx2 |
A |
C |
9: 31,824,308 (GRCm39) |
I27S |
probably damaging |
Het |
| Btnl1 |
A |
T |
17: 34,598,725 (GRCm39) |
I114L |
possibly damaging |
Het |
| Casq1 |
C |
T |
1: 172,043,097 (GRCm39) |
A200T |
probably damaging |
Het |
| Ccdc33 |
T |
A |
9: 58,024,451 (GRCm39) |
E225D |
probably benign |
Het |
| Cd84 |
C |
A |
1: 171,712,152 (GRCm39) |
|
probably null |
Het |
| Ceacam9 |
T |
G |
7: 16,459,232 (GRCm39) |
L177R |
probably benign |
Het |
| Cenpi |
T |
A |
X: 133,218,782 (GRCm39) |
F161L |
possibly damaging |
Het |
| Cep63 |
T |
C |
9: 102,480,079 (GRCm39) |
K251E |
probably damaging |
Het |
| Cetn3 |
A |
G |
13: 81,932,816 (GRCm39) |
E25G |
probably damaging |
Het |
| Ddx19b |
T |
C |
8: 111,735,975 (GRCm39) |
T357A |
possibly damaging |
Het |
| Dpep2 |
A |
C |
8: 106,716,087 (GRCm39) |
Y266* |
probably null |
Het |
| Dqx1 |
G |
A |
6: 83,035,558 (GRCm39) |
D24N |
probably damaging |
Het |
| Dsg4 |
A |
T |
18: 20,604,269 (GRCm39) |
Y912F |
probably damaging |
Het |
| Fezf2 |
G |
T |
14: 12,344,405 (GRCm38) |
P261T |
probably benign |
Het |
| Fmo1 |
T |
C |
1: 162,667,325 (GRCm39) |
I163M |
possibly damaging |
Het |
| Garin1a |
A |
G |
6: 29,285,921 (GRCm39) |
T69A |
probably benign |
Het |
| Gatad2a |
G |
A |
8: 70,365,782 (GRCm39) |
R428* |
probably null |
Het |
| Gfpt1 |
T |
A |
6: 87,031,612 (GRCm39) |
F85I |
possibly damaging |
Het |
| Gimap7 |
A |
T |
6: 48,701,175 (GRCm39) |
I254F |
possibly damaging |
Het |
| Glcci1 |
T |
C |
6: 8,592,980 (GRCm39) |
S261P |
probably damaging |
Het |
| Glis3 |
A |
T |
19: 28,508,674 (GRCm39) |
F437I |
probably damaging |
Het |
| Glp1r |
C |
A |
17: 31,144,601 (GRCm39) |
S258* |
probably null |
Het |
| Gpt2 |
C |
T |
8: 86,242,832 (GRCm39) |
A288V |
possibly damaging |
Het |
| Grin2c |
G |
T |
11: 115,151,731 (GRCm39) |
S76R |
possibly damaging |
Het |
| Guf1 |
T |
A |
5: 69,724,569 (GRCm39) |
Y447* |
probably null |
Het |
| H2-T9 |
T |
A |
17: 36,439,614 (GRCm39) |
D122V |
probably damaging |
Het |
| Hectd1 |
A |
C |
12: 51,832,624 (GRCm39) |
L916V |
probably damaging |
Het |
| Hnf4g |
A |
G |
3: 3,703,268 (GRCm39) |
K96E |
probably damaging |
Het |
| Hsh2d |
G |
A |
8: 72,954,304 (GRCm39) |
D229N |
probably benign |
Het |
| Ifi207 |
T |
G |
1: 173,562,805 (GRCm39) |
M114L |
probably benign |
Het |
| Ifi35 |
A |
T |
11: 101,349,112 (GRCm39) |
E252V |
probably damaging |
Het |
| Igsf9b |
G |
A |
9: 27,233,535 (GRCm39) |
R345H |
possibly damaging |
Het |
| Itih3 |
T |
C |
14: 30,645,540 (GRCm39) |
|
probably benign |
Het |
| Kcnh8 |
GAGACCAACGAGCAGCTGATGCTTCAGA |
GAGA |
17: 53,032,934 (GRCm39) |
74 |
probably benign |
Het |
| Kidins220 |
A |
T |
12: 25,101,193 (GRCm39) |
M1252L |
probably benign |
Het |
| Kifap3 |
T |
A |
1: 163,689,591 (GRCm39) |
L525* |
probably null |
Het |
| Limk2 |
A |
T |
11: 3,305,461 (GRCm39) |
D35E |
probably benign |
Het |
| Lrrc37a |
G |
A |
11: 103,389,792 (GRCm39) |
P1878S |
probably benign |
Het |
| Mansc4 |
T |
A |
6: 146,977,173 (GRCm39) |
I148F |
probably benign |
Het |
| Mei1 |
A |
G |
15: 81,987,513 (GRCm39) |
N859S |
probably benign |
Het |
| Mib1 |
A |
G |
18: 10,812,064 (GRCm39) |
D987G |
probably damaging |
Het |
| Mroh8 |
A |
G |
2: 157,113,895 (GRCm39) |
V132A |
possibly damaging |
Het |
| Npnt |
T |
C |
3: 132,653,893 (GRCm39) |
I29M |
probably benign |
Het |
| Nrap |
T |
C |
19: 56,372,537 (GRCm39) |
D138G |
probably damaging |
Het |
| Or10a3m |
A |
G |
7: 108,312,902 (GRCm39) |
Y102C |
probably damaging |
Het |
| Or1e16 |
A |
T |
11: 73,285,918 (GRCm39) |
I310N |
probably benign |
Het |
| Or2h1 |
T |
A |
17: 37,404,700 (GRCm39) |
E22V |
probably damaging |
Het |
| Or6z7 |
T |
C |
7: 6,483,931 (GRCm39) |
M75V |
probably benign |
Het |
| Osbpl5 |
A |
C |
7: 143,295,408 (GRCm39) |
|
probably null |
Het |
| Pcna-ps2 |
T |
C |
19: 9,261,047 (GRCm39) |
V102A |
possibly damaging |
Het |
| Pik3c2g |
T |
C |
6: 139,599,546 (GRCm39) |
S221P |
probably damaging |
Het |
| Plppr3 |
A |
G |
10: 79,702,259 (GRCm39) |
I271T |
probably damaging |
Het |
| Ppp4r3c1 |
A |
T |
X: 88,975,051 (GRCm39) |
V382E |
probably damaging |
Het |
| Pramel25 |
C |
A |
4: 143,521,720 (GRCm39) |
H445Q |
probably benign |
Het |
| Prkar1b |
C |
T |
5: 139,113,398 (GRCm39) |
A41T |
probably benign |
Het |
| Prkcsh |
A |
G |
9: 21,924,164 (GRCm39) |
D458G |
probably damaging |
Het |
| Prr14 |
G |
T |
7: 127,074,662 (GRCm39) |
R398L |
possibly damaging |
Het |
| Ptafr |
A |
G |
4: 132,307,296 (GRCm39) |
R229G |
probably damaging |
Het |
| Rbp3 |
T |
C |
14: 33,676,502 (GRCm39) |
F150S |
probably damaging |
Het |
| Rel |
C |
T |
11: 23,692,761 (GRCm39) |
G424D |
probably benign |
Het |
| Rlf |
T |
C |
4: 121,007,309 (GRCm39) |
Y557C |
probably damaging |
Het |
| Samt3 |
A |
C |
X: 85,090,740 (GRCm39) |
M211L |
probably benign |
Het |
| Selenop |
A |
T |
15: 3,305,176 (GRCm39) |
I111F |
probably damaging |
Het |
| Slc2a2 |
G |
A |
3: 28,771,590 (GRCm39) |
M173I |
probably benign |
Het |
| Slc43a1 |
G |
T |
2: 84,687,233 (GRCm39) |
G361V |
possibly damaging |
Het |
| Slit2 |
G |
A |
5: 48,407,178 (GRCm39) |
V870M |
probably damaging |
Het |
| Ssxb10 |
A |
G |
X: 8,197,258 (GRCm39) |
D77G |
probably benign |
Het |
| Stk32b |
T |
A |
5: 37,806,458 (GRCm39) |
I29F |
probably damaging |
Het |
| Stra6l |
T |
A |
4: 45,867,237 (GRCm39) |
C161* |
probably null |
Het |
| Tecpr2 |
T |
A |
12: 110,921,219 (GRCm39) |
M1264K |
probably benign |
Het |
| Tfap2c |
A |
T |
2: 172,399,156 (GRCm39) |
I468F |
probably damaging |
Het |
| Ticam1 |
C |
T |
17: 56,578,555 (GRCm39) |
R180H |
probably damaging |
Het |
| Tlr4 |
T |
A |
4: 66,759,272 (GRCm39) |
N688K |
probably benign |
Het |
| Tmem35b |
A |
T |
4: 127,019,846 (GRCm39) |
|
probably benign |
Het |
| Ugt2b34 |
T |
C |
5: 87,054,172 (GRCm39) |
E203G |
probably damaging |
Het |
| Vegfa |
A |
C |
17: 46,329,786 (GRCm39) |
*393G |
probably null |
Het |
| Vmn2r16 |
T |
C |
5: 109,511,890 (GRCm39) |
V699A |
probably benign |
Het |
| Zfp324 |
T |
C |
7: 12,705,145 (GRCm39) |
S445P |
probably damaging |
Het |
| Zfp982 |
T |
A |
4: 147,597,049 (GRCm39) |
C135* |
probably null |
Het |
| Zfp990 |
A |
C |
4: 145,263,439 (GRCm39) |
N146H |
probably damaging |
Het |
| Zfyve26 |
A |
G |
12: 79,302,017 (GRCm39) |
Y431H |
possibly damaging |
Het |
|
| Other mutations in Crybg3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00516:Crybg3
|
APN |
16 |
59,350,803 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01305:Crybg3
|
APN |
16 |
59,349,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01809:Crybg3
|
APN |
16 |
59,345,216 (GRCm39) |
critical splice donor site |
probably benign |
0.00 |
|
IGL02247:Crybg3
|
APN |
16 |
59,323,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02252:Crybg3
|
APN |
16 |
59,372,887 (GRCm39) |
splice site |
probably benign |
|
|
IGL03036:Crybg3
|
APN |
16 |
59,375,542 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL03202:Crybg3
|
APN |
16 |
59,315,072 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03232:Crybg3
|
APN |
16 |
59,350,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU22:Crybg3
|
UTSW |
16 |
59,349,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Crybg3
|
UTSW |
16 |
59,386,019 (GRCm39) |
splice site |
probably benign |
|
|
R0335:Crybg3
|
UTSW |
16 |
59,364,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0691:Crybg3
|
UTSW |
16 |
59,385,574 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1511:Crybg3
|
UTSW |
16 |
59,374,475 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1579:Crybg3
|
UTSW |
16 |
59,350,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1965:Crybg3
|
UTSW |
16 |
59,323,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2225:Crybg3
|
UTSW |
16 |
59,375,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4074:Crybg3
|
UTSW |
16 |
59,376,120 (GRCm39) |
unclassified |
probably benign |
|
|
R4210:Crybg3
|
UTSW |
16 |
59,364,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4393:Crybg3
|
UTSW |
16 |
59,380,458 (GRCm39) |
unclassified |
probably benign |
|
|
R4394:Crybg3
|
UTSW |
16 |
59,380,458 (GRCm39) |
unclassified |
probably benign |
|
|
R4397:Crybg3
|
UTSW |
16 |
59,380,458 (GRCm39) |
unclassified |
probably benign |
|
|
R4427:Crybg3
|
UTSW |
16 |
59,363,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4578:Crybg3
|
UTSW |
16 |
59,350,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4720:Crybg3
|
UTSW |
16 |
59,360,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4917:Crybg3
|
UTSW |
16 |
59,350,782 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5007:Crybg3
|
UTSW |
16 |
59,378,463 (GRCm39) |
unclassified |
probably benign |
|
|
R5020:Crybg3
|
UTSW |
16 |
59,375,159 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R5155:Crybg3
|
UTSW |
16 |
59,345,264 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5306:Crybg3
|
UTSW |
16 |
59,380,356 (GRCm39) |
unclassified |
probably benign |
|
|
R5342:Crybg3
|
UTSW |
16 |
59,342,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5687:Crybg3
|
UTSW |
16 |
59,379,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5763:Crybg3
|
UTSW |
16 |
59,374,973 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5860:Crybg3
|
UTSW |
16 |
59,385,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5950:Crybg3
|
UTSW |
16 |
59,313,934 (GRCm39) |
unclassified |
probably benign |
|
|
R6007:Crybg3
|
UTSW |
16 |
59,374,837 (GRCm39) |
nonsense |
probably null |
|
|
R6042:Crybg3
|
UTSW |
16 |
59,370,838 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R6049:Crybg3
|
UTSW |
16 |
59,364,417 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6242:Crybg3
|
UTSW |
16 |
59,376,053 (GRCm39) |
missense |
probably benign |
|
|
R6301:Crybg3
|
UTSW |
16 |
59,350,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6408:Crybg3
|
UTSW |
16 |
59,316,053 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6724:Crybg3
|
UTSW |
16 |
59,364,501 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6745:Crybg3
|
UTSW |
16 |
59,372,607 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6777:Crybg3
|
UTSW |
16 |
59,378,678 (GRCm39) |
unclassified |
probably benign |
|
|
R6843:Crybg3
|
UTSW |
16 |
59,380,159 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6914:Crybg3
|
UTSW |
16 |
59,360,183 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6942:Crybg3
|
UTSW |
16 |
59,360,183 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7033:Crybg3
|
UTSW |
16 |
59,374,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7091:Crybg3
|
UTSW |
16 |
59,377,531 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7133:Crybg3
|
UTSW |
16 |
59,357,167 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7193:Crybg3
|
UTSW |
16 |
59,379,956 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7204:Crybg3
|
UTSW |
16 |
59,379,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7398:Crybg3
|
UTSW |
16 |
59,377,688 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7666:Crybg3
|
UTSW |
16 |
59,379,700 (GRCm39) |
nonsense |
probably null |
|
|
R7691:Crybg3
|
UTSW |
16 |
59,376,497 (GRCm39) |
missense |
not run |
|
|
R7714:Crybg3
|
UTSW |
16 |
59,379,236 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7860:Crybg3
|
UTSW |
16 |
59,375,605 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7901:Crybg3
|
UTSW |
16 |
59,377,907 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8371:Crybg3
|
UTSW |
16 |
59,377,414 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8394:Crybg3
|
UTSW |
16 |
59,378,651 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8438:Crybg3
|
UTSW |
16 |
59,385,655 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8529:Crybg3
|
UTSW |
16 |
59,376,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8699:Crybg3
|
UTSW |
16 |
59,375,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8766:Crybg3
|
UTSW |
16 |
59,375,696 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8767:Crybg3
|
UTSW |
16 |
59,376,500 (GRCm39) |
missense |
probably benign |
|
|
R8789:Crybg3
|
UTSW |
16 |
59,375,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8871:Crybg3
|
UTSW |
16 |
59,378,519 (GRCm39) |
missense |
probably benign |
|
|
R8878:Crybg3
|
UTSW |
16 |
59,380,547 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8894:Crybg3
|
UTSW |
16 |
59,342,552 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8928:Crybg3
|
UTSW |
16 |
59,376,715 (GRCm39) |
missense |
probably benign |
0.40 |
|
R8928:Crybg3
|
UTSW |
16 |
59,315,123 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8939:Crybg3
|
UTSW |
16 |
59,376,512 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9010:Crybg3
|
UTSW |
16 |
59,374,702 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9266:Crybg3
|
UTSW |
16 |
59,372,544 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9348:Crybg3
|
UTSW |
16 |
59,421,256 (GRCm39) |
start codon destroyed |
probably null |
0.66 |
|
R9353:Crybg3
|
UTSW |
16 |
59,421,107 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9406:Crybg3
|
UTSW |
16 |
59,378,839 (GRCm39) |
missense |
probably benign |
0.42 |
|
R9429:Crybg3
|
UTSW |
16 |
59,375,556 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9464:Crybg3
|
UTSW |
16 |
59,376,120 (GRCm39) |
unclassified |
probably benign |
|
|
R9621:Crybg3
|
UTSW |
16 |
59,326,613 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9703:Crybg3
|
UTSW |
16 |
59,375,939 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9751:Crybg3
|
UTSW |
16 |
59,377,887 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9766:Crybg3
|
UTSW |
16 |
59,376,207 (GRCm39) |
missense |
probably benign |
0.03 |
|
RF007:Crybg3
|
UTSW |
16 |
59,377,067 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Z1177:Crybg3
|
UTSW |
16 |
59,376,841 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1177:Crybg3
|
UTSW |
16 |
59,375,756 (GRCm39) |
nonsense |
probably null |
|
|
Z1187:Crybg3
|
UTSW |
16 |
59,326,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGCCAGGAAGTCGTCTTTC -3'
(R):5'- CAACCGGCGTTGTTCTTGTG -3'
Sequencing Primer
(F):5'- GAAGTCGTCTTTCTTGGGTACCC -3'
(R):5'- CTTGTGGAGAAATCCCATGGCAC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation