Incidental Mutation 'R1986:Arhgap45'
| ID |
220681 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap45
|
| Ensembl Gene |
ENSMUSG00000035697 |
| Gene Name |
Rho GTPase activating protein 45 |
| Synonyms |
6330406L22Rik, Hmha1 |
| MMRRC Submission |
039998-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1986 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
79852505-79867305 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 79856530 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 26
(L26P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041019
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043311]
[ENSMUST00000099501]
[ENSMUST00000105373]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043311
AA Change: L26P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000041019
Gene: ENSMUSG00000035697
AA Change: L26P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
142 |
153 |
N/A |
INTRINSIC |
|
FCH
|
157 |
244 |
4.14e-17 |
SMART |
|
low complexity region
|
255 |
269 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
330 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
536 |
N/A |
INTRINSIC |
|
C1
|
582 |
628 |
3.15e-8 |
SMART |
|
RhoGAP
|
653 |
852 |
2.73e-73 |
SMART |
|
low complexity region
|
856 |
869 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
876 |
999 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099501
AA Change: L142P
PolyPhen 2
Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000097100
Gene: ENSMUSG00000035697
AA Change: L142P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
258 |
269 |
N/A |
INTRINSIC |
|
FCH
|
273 |
360 |
4.14e-17 |
SMART |
|
low complexity region
|
371 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
440 |
N/A |
INTRINSIC |
|
low complexity region
|
446 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
643 |
652 |
N/A |
INTRINSIC |
|
C1
|
698 |
744 |
3.15e-8 |
SMART |
|
RhoGAP
|
769 |
968 |
2.73e-73 |
SMART |
|
low complexity region
|
972 |
985 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
992 |
1115 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105373
AA Change: L153P
PolyPhen 2
Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000101012
Gene: ENSMUSG00000035697
AA Change: L153P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
269 |
280 |
N/A |
INTRINSIC |
|
FCH
|
284 |
371 |
4.14e-17 |
SMART |
|
low complexity region
|
382 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
654 |
663 |
N/A |
INTRINSIC |
|
C1
|
709 |
755 |
3.15e-8 |
SMART |
|
RhoGAP
|
780 |
979 |
2.73e-73 |
SMART |
|
low complexity region
|
983 |
996 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
1003 |
1126 |
1e-21 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140974
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150022
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700006A11Rik |
A |
G |
3: 124,212,977 (GRCm39) |
S105P |
probably damaging |
Het |
| 9930111J21Rik2 |
T |
A |
11: 48,910,119 (GRCm39) |
K771N |
possibly damaging |
Het |
| Abcc2 |
A |
G |
19: 43,818,318 (GRCm39) |
E1268G |
probably damaging |
Het |
| Adamts4 |
T |
C |
1: 171,084,244 (GRCm39) |
F574L |
possibly damaging |
Het |
| Adamts9 |
A |
G |
6: 92,773,375 (GRCm39) |
V1165A |
probably benign |
Het |
| Agap2 |
A |
T |
10: 126,918,913 (GRCm39) |
K430* |
probably null |
Het |
| Amn |
G |
T |
12: 111,241,431 (GRCm39) |
G232V |
probably damaging |
Het |
| Ank3 |
A |
G |
10: 69,703,258 (GRCm39) |
E297G |
probably damaging |
Het |
| Atp10b |
C |
A |
11: 43,063,595 (GRCm39) |
Q177K |
probably benign |
Het |
| Bbs10 |
A |
T |
10: 111,135,118 (GRCm39) |
D77V |
probably damaging |
Het |
| Bltp2 |
A |
T |
11: 78,165,438 (GRCm39) |
H1318L |
probably damaging |
Het |
| Bpifa1 |
T |
A |
2: 153,986,256 (GRCm39) |
L127Q |
probably damaging |
Het |
| Brinp2 |
T |
C |
1: 158,074,348 (GRCm39) |
N591S |
probably damaging |
Het |
| C2cd2 |
A |
C |
16: 97,671,471 (GRCm39) |
V476G |
probably damaging |
Het |
| C7 |
T |
A |
15: 5,041,494 (GRCm39) |
T471S |
possibly damaging |
Het |
| Cacna1b |
A |
T |
2: 24,538,998 (GRCm39) |
Y1488N |
probably damaging |
Het |
| Cadps2 |
A |
G |
6: 23,323,379 (GRCm39) |
F1001L |
probably damaging |
Het |
| Ccdc188 |
T |
C |
16: 18,036,707 (GRCm39) |
S216P |
probably damaging |
Het |
| Ccdc24 |
A |
G |
4: 117,729,213 (GRCm39) |
L88P |
probably damaging |
Het |
| Dab1 |
T |
C |
4: 104,470,412 (GRCm39) |
I65T |
probably damaging |
Het |
| Dock4 |
A |
T |
12: 40,780,062 (GRCm39) |
D621V |
probably damaging |
Het |
| Drd5 |
A |
T |
5: 38,477,456 (GRCm39) |
M150L |
probably damaging |
Het |
| Eef2k |
T |
A |
7: 120,472,569 (GRCm39) |
M94K |
possibly damaging |
Het |
| Epg5 |
A |
G |
18: 78,025,521 (GRCm39) |
|
probably null |
Het |
| Epsti1 |
T |
C |
14: 78,169,673 (GRCm39) |
|
probably null |
Het |
| Ern2 |
T |
A |
7: 121,770,752 (GRCm39) |
D754V |
probably benign |
Het |
| Fbxo6 |
A |
G |
4: 148,230,552 (GRCm39) |
Y237H |
probably damaging |
Het |
| Fbxw24 |
A |
G |
9: 109,436,124 (GRCm39) |
S303P |
probably damaging |
Het |
| Fpr-rs3 |
A |
T |
17: 20,844,103 (GRCm39) |
|
probably null |
Het |
| Gab1 |
G |
T |
8: 81,493,010 (GRCm39) |
T679K |
probably damaging |
Het |
| Gbp9 |
C |
A |
5: 105,253,590 (GRCm39) |
V42F |
probably damaging |
Het |
| Gbp9 |
A |
T |
5: 105,253,652 (GRCm39) |
V21E |
probably damaging |
Het |
| Gm20821 |
A |
G |
Y: 9,783,927 (GRCm39) |
Q183R |
probably benign |
Het |
| Gpatch11 |
A |
T |
17: 79,151,266 (GRCm39) |
I226F |
probably benign |
Het |
| Hephl1 |
T |
G |
9: 14,965,848 (GRCm39) |
E1035A |
probably damaging |
Het |
| Hspa4l |
T |
C |
3: 40,714,833 (GRCm39) |
V156A |
probably damaging |
Het |
| Ifna13 |
A |
G |
4: 88,562,588 (GRCm39) |
V12A |
probably benign |
Het |
| Il24 |
G |
A |
1: 130,810,268 (GRCm39) |
T196I |
probably benign |
Het |
| Irgm2 |
A |
G |
11: 58,110,384 (GRCm39) |
D37G |
probably benign |
Het |
| Irs1 |
A |
G |
1: 82,266,486 (GRCm39) |
S577P |
probably damaging |
Het |
| Kif21b |
G |
A |
1: 136,075,284 (GRCm39) |
D166N |
probably damaging |
Het |
| Krtap4-16 |
T |
C |
11: 99,742,322 (GRCm39) |
Q26R |
unknown |
Het |
| Lig1 |
T |
A |
7: 13,043,067 (GRCm39) |
Y837* |
probably null |
Het |
| Lrrc69 |
T |
C |
4: 14,708,669 (GRCm39) |
E225G |
possibly damaging |
Het |
| Map3k20 |
C |
T |
2: 72,271,638 (GRCm39) |
Q589* |
probably null |
Het |
| Masp1 |
T |
G |
16: 23,302,211 (GRCm39) |
M347L |
probably benign |
Het |
| Mgat3 |
A |
T |
15: 80,096,390 (GRCm39) |
I406F |
probably benign |
Het |
| Mmp1b |
T |
G |
9: 7,368,577 (GRCm39) |
D425A |
probably benign |
Het |
| Mss51 |
T |
C |
14: 20,533,259 (GRCm39) |
H404R |
probably benign |
Het |
| Myo15b |
A |
T |
11: 115,773,701 (GRCm39) |
H1911L |
probably benign |
Het |
| Nedd4l |
A |
G |
18: 65,276,874 (GRCm39) |
D102G |
probably damaging |
Het |
| Niban3 |
T |
A |
8: 72,056,404 (GRCm39) |
I368N |
possibly damaging |
Het |
| Npc2 |
T |
C |
12: 84,807,523 (GRCm39) |
K112E |
probably benign |
Het |
| Nuggc |
T |
A |
14: 65,879,370 (GRCm39) |
V694E |
probably damaging |
Het |
| Olfm1 |
T |
G |
2: 28,104,718 (GRCm39) |
V157G |
probably benign |
Het |
| Or10h28 |
T |
C |
17: 33,488,489 (GRCm39) |
S264P |
probably benign |
Het |
| Or5p55 |
T |
C |
7: 107,566,877 (GRCm39) |
V91A |
probably benign |
Het |
| Otogl |
T |
A |
10: 107,630,051 (GRCm39) |
|
probably null |
Het |
| Ovgp1 |
G |
A |
3: 105,882,251 (GRCm39) |
C38Y |
probably damaging |
Het |
| Pisd |
A |
T |
5: 32,894,672 (GRCm39) |
S344T |
probably damaging |
Het |
| Psme4 |
T |
C |
11: 30,780,352 (GRCm39) |
V840A |
probably benign |
Het |
| Ptch1 |
T |
G |
13: 63,672,773 (GRCm39) |
E944A |
probably benign |
Het |
| Rims2 |
T |
A |
15: 39,208,710 (GRCm39) |
M171K |
probably damaging |
Het |
| Rin2 |
T |
A |
2: 145,720,860 (GRCm39) |
M731K |
probably damaging |
Het |
| Scgb1b19 |
T |
C |
7: 32,987,108 (GRCm39) |
|
probably null |
Het |
| Serpina10 |
A |
G |
12: 103,594,514 (GRCm39) |
I235T |
possibly damaging |
Het |
| Setbp1 |
T |
A |
18: 78,901,759 (GRCm39) |
E636V |
probably damaging |
Het |
| Sh3d21 |
C |
T |
4: 126,056,290 (GRCm39) |
E101K |
probably damaging |
Het |
| Ski |
T |
G |
4: 155,306,148 (GRCm39) |
D225A |
probably damaging |
Het |
| Slc28a2b |
A |
G |
2: 122,357,910 (GRCm39) |
T655A |
probably benign |
Het |
| Slc29a3 |
T |
C |
10: 60,559,593 (GRCm39) |
Y187C |
probably damaging |
Het |
| Sort1 |
T |
A |
3: 108,253,043 (GRCm39) |
D494E |
possibly damaging |
Het |
| Sphkap |
A |
T |
1: 83,255,643 (GRCm39) |
L702Q |
probably damaging |
Het |
| Srr |
A |
G |
11: 74,799,545 (GRCm39) |
I285T |
probably damaging |
Het |
| Stam2 |
T |
C |
2: 52,599,638 (GRCm39) |
T257A |
possibly damaging |
Het |
| Suds3 |
A |
T |
5: 117,246,417 (GRCm39) |
N112K |
probably damaging |
Het |
| Tedc2 |
T |
A |
17: 24,435,291 (GRCm39) |
E366V |
probably damaging |
Het |
| Tedc2 |
C |
A |
17: 24,435,292 (GRCm39) |
E366* |
probably null |
Het |
| Tesk2 |
T |
C |
4: 116,608,390 (GRCm39) |
L104P |
probably damaging |
Het |
| Tie1 |
C |
T |
4: 118,336,160 (GRCm39) |
R702H |
probably benign |
Het |
| Tpo |
G |
T |
12: 30,169,465 (GRCm39) |
A90E |
probably damaging |
Het |
| Trim30a |
T |
C |
7: 104,060,672 (GRCm39) |
D368G |
probably damaging |
Het |
| Ugt2a2 |
A |
T |
5: 87,608,438 (GRCm39) |
M633K |
possibly damaging |
Het |
| Vars2 |
A |
G |
17: 35,970,953 (GRCm39) |
W626R |
probably damaging |
Het |
| Vmn2r10 |
A |
T |
5: 109,154,120 (GRCm39) |
Y61* |
probably null |
Het |
| Vmn2r95 |
T |
C |
17: 18,671,805 (GRCm39) |
V514A |
probably benign |
Het |
| Vwa5a |
T |
G |
9: 38,649,110 (GRCm39) |
|
probably benign |
Het |
| Zfp365 |
A |
T |
10: 67,745,686 (GRCm39) |
C31S |
probably damaging |
Het |
| Zfp397 |
A |
T |
18: 24,093,108 (GRCm39) |
I198F |
possibly damaging |
Het |
| Zfp407 |
C |
T |
18: 84,577,898 (GRCm39) |
A1072T |
probably benign |
Het |
| Zfp593 |
T |
C |
4: 133,972,206 (GRCm39) |
E100G |
possibly damaging |
Het |
|
| Other mutations in Arhgap45 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01360:Arhgap45
|
APN |
10 |
79,864,482 (GRCm39) |
splice site |
probably benign |
|
|
IGL01414:Arhgap45
|
APN |
10 |
79,862,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01505:Arhgap45
|
APN |
10 |
79,862,376 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02203:Arhgap45
|
APN |
10 |
79,863,387 (GRCm39) |
nonsense |
probably null |
|
|
IGL02557:Arhgap45
|
APN |
10 |
79,857,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arhgap45
|
APN |
10 |
79,853,768 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03292:Arhgap45
|
APN |
10 |
79,856,803 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03352:Arhgap45
|
APN |
10 |
79,866,585 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Celt
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
celtic
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
druid
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
Mistletoe
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
Roman
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stonehenge
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03048:Arhgap45
|
UTSW |
10 |
79,852,851 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4677001:Arhgap45
|
UTSW |
10 |
79,856,583 (GRCm39) |
missense |
probably benign |
|
|
R0532:Arhgap45
|
UTSW |
10 |
79,857,917 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1233:Arhgap45
|
UTSW |
10 |
79,863,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Arhgap45
|
UTSW |
10 |
79,864,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1666:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1668:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1688:Arhgap45
|
UTSW |
10 |
79,864,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Arhgap45
|
UTSW |
10 |
79,853,932 (GRCm39) |
nonsense |
probably null |
|
|
R1902:Arhgap45
|
UTSW |
10 |
79,861,300 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1912:Arhgap45
|
UTSW |
10 |
79,856,524 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1935:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1955:Arhgap45
|
UTSW |
10 |
79,862,326 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1968:Arhgap45
|
UTSW |
10 |
79,863,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1977:Arhgap45
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2074:Arhgap45
|
UTSW |
10 |
79,863,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2081:Arhgap45
|
UTSW |
10 |
79,863,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2162:Arhgap45
|
UTSW |
10 |
79,852,813 (GRCm39) |
start codon destroyed |
probably null |
0.02 |
|
R2937:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2938:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3081:Arhgap45
|
UTSW |
10 |
79,862,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4695:Arhgap45
|
UTSW |
10 |
79,861,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4736:Arhgap45
|
UTSW |
10 |
79,862,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4758:Arhgap45
|
UTSW |
10 |
79,866,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Arhgap45
|
UTSW |
10 |
79,856,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4943:Arhgap45
|
UTSW |
10 |
79,862,337 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5102:Arhgap45
|
UTSW |
10 |
79,857,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5128:Arhgap45
|
UTSW |
10 |
79,866,793 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5667:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5671:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5920:Arhgap45
|
UTSW |
10 |
79,864,965 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5998:Arhgap45
|
UTSW |
10 |
79,866,784 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6276:Arhgap45
|
UTSW |
10 |
79,862,068 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6675:Arhgap45
|
UTSW |
10 |
79,853,938 (GRCm39) |
missense |
probably null |
0.98 |
|
R6738:Arhgap45
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6783:Arhgap45
|
UTSW |
10 |
79,853,698 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6863:Arhgap45
|
UTSW |
10 |
79,853,616 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6978:Arhgap45
|
UTSW |
10 |
79,857,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7089:Arhgap45
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7215:Arhgap45
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7307:Arhgap45
|
UTSW |
10 |
79,865,016 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7308:Arhgap45
|
UTSW |
10 |
79,862,392 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7480:Arhgap45
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
R7481:Arhgap45
|
UTSW |
10 |
79,858,134 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7649:Arhgap45
|
UTSW |
10 |
79,866,835 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7652:Arhgap45
|
UTSW |
10 |
79,864,672 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7748:Arhgap45
|
UTSW |
10 |
79,852,766 (GRCm39) |
unclassified |
probably benign |
|
|
R7883:Arhgap45
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
R8121:Arhgap45
|
UTSW |
10 |
79,853,909 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8169:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8170:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8175:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8178:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8186:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8187:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8687:Arhgap45
|
UTSW |
10 |
79,852,621 (GRCm39) |
unclassified |
probably benign |
|
|
R8866:Arhgap45
|
UTSW |
10 |
79,853,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Arhgap45
|
UTSW |
10 |
79,855,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9299:Arhgap45
|
UTSW |
10 |
79,862,565 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9412:Arhgap45
|
UTSW |
10 |
79,855,564 (GRCm39) |
start codon destroyed |
probably null |
0.66 |
|
R9579:Arhgap45
|
UTSW |
10 |
79,853,843 (GRCm39) |
missense |
probably benign |
|
|
R9629:Arhgap45
|
UTSW |
10 |
79,863,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Arhgap45
|
UTSW |
10 |
79,857,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0023:Arhgap45
|
UTSW |
10 |
79,866,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
X0063:Arhgap45
|
UTSW |
10 |
79,866,190 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,864,886 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,861,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGGCTTTCCCTCACTGTG -3'
(R):5'- TGTGTTTGTCAAATGCCTATGC -3'
Sequencing Primer
(F):5'- GCACATCTGCAGGGCCAG -3'
(R):5'- TGCCTATGCACCCTTCAAAAC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation