Mutagenetix > Incidental Mutation

Incidental Mutation 'R1971:Tenm3'

220878

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Ten-m3, Odz3, 2610100B16Rik

MMRRC Submission

039984-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.598) question?

Stock #

R1971 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

48227682-48843951 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 48236313 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 2080 (Y2080H)

Ref Sequence

ENSEMBL: ENSMUSP00000033965 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000033965
AA Change: Y2080H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: Y2080H

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000190840
AA Change: Y2064H

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: Y2064H

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Meta Mutation Damage Score

0.2988

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.3%

Validation Efficiency

99% (115/116)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 113 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001O22Rik	A	T	2: 30,796,554 (GRCm38)	I242N	probably benign	Het
2510009E07Rik	G	T	16: 21,653,298 (GRCm38)	Y217*	probably null	Het
4931429L15Rik	C	T	9: 46,308,788 (GRCm38)	V149M	probably benign	Het
9030624J02Rik	A	C	7: 118,775,334 (GRCm38)	R352S	probably damaging	Het
Abcg8	G	T	17: 84,695,159 (GRCm38)		probably benign	Het
Acox1	A	G	11: 116,198,261 (GRCm38)	F77S	probably benign	Het
Adgrb3	G	T	1: 25,547,444 (GRCm38)	H389Q	probably benign	Het
Ak7	A	G	12: 105,726,245 (GRCm38)	N186S	probably damaging	Het
Apobr	A	G	7: 126,586,225 (GRCm38)	T303A	probably benign	Het
Arnt	C	T	3: 95,448,393 (GRCm38)	S16L	possibly damaging	Het
Bcl9l	T	C	9: 44,508,699 (GRCm38)		probably null	Het
Bco2	T	C	9: 50,545,984 (GRCm38)	D86G	probably damaging	Het
Bmpr1b	T	A	3: 141,857,572 (GRCm38)	I204F	probably damaging	Het
Bpifb5	C	A	2: 154,230,344 (GRCm38)	Q324K	probably benign	Het
Cacna2d2	G	A	9: 107,512,006 (GRCm38)	V223I	probably damaging	Het
Capn3	A	G	2: 120,480,747 (GRCm38)	D105G	possibly damaging	Het
Ccdc40	G	T	11: 119,263,075 (GRCm38)		probably null	Het
Ccdc83	T	A	7: 90,244,154 (GRCm38)	S132C	probably damaging	Het
Ckap2l	A	G	2: 129,285,422 (GRCm38)	S279P	possibly damaging	Het
Cldn12	C	A	5: 5,508,137 (GRCm38)	A97S	probably benign	Het
Clec2l	T	G	6: 38,663,374 (GRCm38)	S47A	probably benign	Het
Csnk1d	C	A	11: 120,972,448 (GRCm38)	R222M	possibly damaging	Het
Ctnna1	T	A	18: 35,154,527 (GRCm38)	D96E	probably benign	Het
D630045J12Rik	T	C	6: 38,168,143 (GRCm38)	D1316G	probably damaging	Het
Ddx4	C	T	13: 112,600,013 (GRCm38)	V608I	probably damaging	Het
Dmtf1	T	C	5: 9,148,989 (GRCm38)	E48G	probably benign	Het
Dnah17	G	C	11: 118,104,535 (GRCm38)	Q996E	probably benign	Het
Dnah9	G	C	11: 65,848,371 (GRCm38)	N4180K	probably damaging	Het
Dpf3	T	A	12: 83,325,035 (GRCm38)		probably null	Het
Drd2	T	C	9: 49,407,059 (GRCm38)	F434L	probably damaging	Het
En1	A	G	1: 120,607,013 (GRCm38)	T344A	unknown	Het
Eri3	A	G	4: 117,564,767 (GRCm38)	T81A	probably benign	Het
Fam20a	T	C	11: 109,685,411 (GRCm38)	Y174C	probably damaging	Het
Fam234a	G	C	17: 26,216,655 (GRCm38)		probably null	Het
Fam76a	A	T	4: 132,903,983 (GRCm38)	I217N	probably damaging	Het
Fancm	T	A	12: 65,101,692 (GRCm38)	S694T	probably benign	Het
Fcgbpl1	C	A	7: 28,131,512 (GRCm38)	A50E	possibly damaging	Het
Foxo3	A	G	10: 42,197,262 (GRCm38)	S420P	probably benign	Het
Foxp4	C	T	17: 47,875,871 (GRCm38)	R378Q	unknown	Het
Gm136	T	G	4: 34,755,986 (GRCm38)	D9A	probably benign	Het
Gstt2	G	T	10: 75,832,665 (GRCm38)	T116N	probably benign	Het
Hs3st6	A	G	17: 24,753,293 (GRCm38)	T70A	probably benign	Het
Hspa14	A	G	2: 3,489,767 (GRCm38)	V461A	possibly damaging	Het
Itih5	A	T	2: 10,238,568 (GRCm38)	D372V	probably damaging	Het
Kcna2	A	T	3: 107,104,824 (GRCm38)	R240S	probably damaging	Het
Kctd18	T	C	1: 57,967,620 (GRCm38)	I24V	probably benign	Het
Lap3	T	C	5: 45,506,166 (GRCm38)		probably benign	Het
Lcp1	T	C	14: 75,200,506 (GRCm38)	S119P	probably damaging	Het
Lig3	G	C	11: 82,795,718 (GRCm38)	D642H	probably benign	Het
Lpin1	A	T	12: 16,580,723 (GRCm38)	L58H	probably damaging	Het
Map4k5	G	T	12: 69,826,328 (GRCm38)	P468Q	possibly damaging	Het
Med31	G	A	11: 72,215,418 (GRCm38)		probably benign	Het
Mki67	A	T	7: 135,713,959 (GRCm38)		probably null	Het
Mrc1	G	A	2: 14,244,292 (GRCm38)		probably null	Het
Msh3	T	A	13: 92,249,820 (GRCm38)		probably benign	Het
Msh3	A	G	13: 92,223,276 (GRCm38)	I16T	probably damaging	Het
Mst1r	A	T	9: 107,913,212 (GRCm38)	I675F	probably benign	Het
Myb	A	C	10: 21,140,656 (GRCm38)	S652A	probably benign	Het
Myh2	G	T	11: 67,189,178 (GRCm38)	S1099I	possibly damaging	Het
Myl6b	A	G	10: 128,494,643 (GRCm38)	V181A	probably damaging	Het
Myt1l	A	T	12: 29,827,092 (GRCm38)	K247N	unknown	Het
Nanos2	G	T	7: 18,987,704 (GRCm38)	V34L	probably benign	Het
Nav1	T	C	1: 135,532,353 (GRCm38)	T411A	probably benign	Het
Nedd9	T	A	13: 41,338,948 (GRCm38)	I23F	probably damaging	Het
Nes	G	A	3: 87,978,327 (GRCm38)	V1254I	possibly damaging	Het
Nol6	A	G	4: 41,119,542 (GRCm38)	F588S	probably damaging	Het
Numa1	C	T	7: 102,009,322 (GRCm38)	A1605V	probably damaging	Het
Ofd1	T	C	X: 166,427,214 (GRCm38)	Y205C	probably benign	Het
Olr1	T	C	6: 129,493,535 (GRCm38)	E223G	probably benign	Het
Or1e30	T	A	11: 73,787,790 (GRCm38)	M284K	probably damaging	Het
Or2ag12	T	A	7: 106,677,670 (GRCm38)	N272I	probably damaging	Het
Or4c118	A	T	2: 89,144,734 (GRCm38)	C96*	probably null	Het
Or51k2	A	T	7: 103,946,943 (GRCm38)	I126F	probably damaging	Het
Or51l4	C	T	7: 103,755,320 (GRCm38)	W88*	probably null	Het
Pate6	T	A	9: 35,789,013 (GRCm38)	H92L	probably benign	Het
Pclo	A	G	5: 14,713,473 (GRCm38)	T3987A	unknown	Het
Pik3cg	A	T	12: 32,192,153 (GRCm38)	V986D	probably damaging	Het
Pitpnm1	T	A	19: 4,112,450 (GRCm38)	D1093E	probably damaging	Het
Ppp1r12b	T	C	1: 134,865,913 (GRCm38)	D571G	probably benign	Het
Rfx1	A	G	8: 84,095,497 (GRCm38)	E875G	probably damaging	Het
Rnf145	T	A	11: 44,548,815 (GRCm38)	I146N	probably damaging	Het
Rttn	G	A	18: 89,090,433 (GRCm38)	R1587H	probably benign	Het
Safb	A	G	17: 56,605,821 (GRCm38)	H883R	probably benign	Het
Sdhb	A	G	4: 140,972,949 (GRCm38)	D120G	possibly damaging	Het
Serpine3	A	G	14: 62,665,084 (GRCm38)	N48S	probably damaging	Het
Sgms1	T	A	19: 32,159,957 (GRCm38)	I70L	probably benign	Het
Slc1a7	G	T	4: 107,968,585 (GRCm38)	D14Y	probably benign	Het
Smtnl2	C	T	11: 72,411,357 (GRCm38)	A93T	probably benign	Het
Srpra	T	C	9: 35,213,538 (GRCm38)		probably null	Het
Taf6l	A	G	19: 8,775,502 (GRCm38)		probably null	Het
Tbc1d10b	A	T	7: 127,207,864 (GRCm38)	V167E	probably benign	Het
Tbc1d9	G	A	8: 83,249,510 (GRCm38)	R566H	probably damaging	Het
Tex14	A	G	11: 87,511,605 (GRCm38)	N506S	probably damaging	Het
Thada	G	T	17: 84,310,042 (GRCm38)	P1349T	probably damaging	Het
Tjp1	G	T	7: 65,324,078 (GRCm38)	T476K	probably damaging	Het
Tlr11	A	T	14: 50,361,234 (GRCm38)	T226S	probably benign	Het
Tmem131	G	A	1: 36,804,599 (GRCm38)	Q1394*	probably null	Het
Tmem161a	C	T	8: 70,176,909 (GRCm38)	R58W	probably damaging	Het
Tmem219	T	C	7: 126,897,250 (GRCm38)	S13G	probably benign	Het
Trp53bp1	T	C	2: 121,205,036 (GRCm38)	Y47C	probably damaging	Het
Ttn	T	A	2: 76,901,578 (GRCm38)		probably benign	Het
Ush1g	A	G	11: 115,318,454 (GRCm38)	S305P	probably damaging	Het
Usp37	A	T	1: 74,439,968 (GRCm38)	Y948*	probably null	Het
Vav1	A	T	17: 57,327,697 (GRCm38)	Y805F	probably damaging	Het
Vmn1r59	A	T	7: 5,454,039 (GRCm38)	Y241N	probably damaging	Het
Vmn2r2	T	A	3: 64,126,700 (GRCm38)	Y467F	probably damaging	Het
Vps54	C	A	11: 21,292,051 (GRCm38)	L389I	probably damaging	Het
Vwa8	G	T	14: 78,925,254 (GRCm38)		probably benign	Het
Wdr19	G	T	5: 65,241,160 (GRCm38)		probably benign	Het
Wnt2b	A	T	3: 104,954,617 (GRCm38)		probably benign	Het
Xirp2	A	G	2: 67,511,695 (GRCm38)	R1427G	possibly damaging	Het
Ylpm1	T	C	12: 85,040,786 (GRCm38)	S1115P	probably damaging	Het
Zfp946	T	A	17: 22,455,425 (GRCm38)	C387S	probably damaging	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,417,060 (GRCm38)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,236,025 (GRCm38)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,279,042 (GRCm38)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,276,421 (GRCm38)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,417,132 (GRCm38)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,256,841 (GRCm38)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,236,423 (GRCm38)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,276,645 (GRCm38)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,228,802 (GRCm38)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,254,477 (GRCm38)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,236,758 (GRCm38)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,276,396 (GRCm38)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,276,576 (GRCm38)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,235,476 (GRCm38)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,236,694 (GRCm38)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,279,198 (GRCm38)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,288,016 (GRCm38)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,299,639 (GRCm38)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,298,956 (GRCm38)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,276,903 (GRCm38)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,298,878 (GRCm38)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	48,646,418 (GRCm38)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,235,523 (GRCm38)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,235,346 (GRCm38)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,235,607 (GRCm38)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,293,657 (GRCm38)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,343,345 (GRCm38)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,342,659 (GRCm38)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,341,034 (GRCm38)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,236,912 (GRCm38)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,232,105 (GRCm38)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,228,975 (GRCm38)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,287,791 (GRCm38)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,341,160 (GRCm38)	splice site	probably benign
R0573:Tenm3	UTSW	8	48,674,399 (GRCm38)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,277,710 (GRCm38)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,276,156 (GRCm38)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,236,525 (GRCm38)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,236,594 (GRCm38)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,335,742 (GRCm38)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,298,965 (GRCm38)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,228,542 (GRCm38)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,235,582 (GRCm38)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,240,396 (GRCm38)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,287,893 (GRCm38)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,276,400 (GRCm38)	missense	probably benign
R1455:Tenm3	UTSW	8	48,279,048 (GRCm38)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,235,971 (GRCm38)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,310,625 (GRCm38)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,343,316 (GRCm38)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,287,822 (GRCm38)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,395,576 (GRCm38)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,228,981 (GRCm38)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,236,421 (GRCm38)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,228,993 (GRCm38)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,279,074 (GRCm38)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,417,119 (GRCm38)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,310,634 (GRCm38)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,232,104 (GRCm38)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,417,179 (GRCm38)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	48,674,544 (GRCm38)	missense	probably damaging	0.98
R1801:Tenm3	UTSW	8	48,276,256 (GRCm38)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,276,346 (GRCm38)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,310,761 (GRCm38)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,228,591 (GRCm38)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,228,668 (GRCm38)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,342,256 (GRCm38)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,343,349 (GRCm38)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,417,006 (GRCm38)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,395,544 (GRCm38)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	48,674,550 (GRCm38)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,342,337 (GRCm38)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,287,953 (GRCm38)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,240,270 (GRCm38)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,228,555 (GRCm38)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,277,746 (GRCm38)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,349,223 (GRCm38)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,349,404 (GRCm38)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,395,658 (GRCm38)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,293,726 (GRCm38)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,235,970 (GRCm38)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,310,621 (GRCm38)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,235,821 (GRCm38)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,276,861 (GRCm38)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,300,971 (GRCm38)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,278,961 (GRCm38)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,229,137 (GRCm38)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,235,826 (GRCm38)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,342,308 (GRCm38)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,229,198 (GRCm38)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,236,855 (GRCm38)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,287,831 (GRCm38)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,236,564 (GRCm38)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,367,377 (GRCm38)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,279,006 (GRCm38)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,236,764 (GRCm38)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,228,762 (GRCm38)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	48,646,498 (GRCm38)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	48,646,447 (GRCm38)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,228,508 (GRCm38)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,343,406 (GRCm38)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,395,573 (GRCm38)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,298,808 (GRCm38)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,254,622 (GRCm38)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,293,665 (GRCm38)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,417,059 (GRCm38)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,367,394 (GRCm38)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,276,849 (GRCm38)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,236,063 (GRCm38)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6516:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6747:Tenm3	UTSW	8	48,343,243 (GRCm38)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	48,646,256 (GRCm38)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	48,674,493 (GRCm38)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,256,837 (GRCm38)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,276,738 (GRCm38)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	48,674,416 (GRCm38)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,240,479 (GRCm38)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,240,444 (GRCm38)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	48,674,553 (GRCm38)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,292,236 (GRCm38)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,300,969 (GRCm38)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,235,935 (GRCm38)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,236,177 (GRCm38)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,236,183 (GRCm38)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,287,812 (GRCm38)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,276,600 (GRCm38)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,341,049 (GRCm38)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,335,727 (GRCm38)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	48,646,333 (GRCm38)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,236,465 (GRCm38)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,276,300 (GRCm38)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,229,111 (GRCm38)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,310,703 (GRCm38)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,367,422 (GRCm38)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,293,773 (GRCm38)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,287,848 (GRCm38)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,293,509 (GRCm38)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,229,181 (GRCm38)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,342,633 (GRCm38)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,299,645 (GRCm38)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,349,356 (GRCm38)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,342,449 (GRCm38)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,310,724 (GRCm38)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8831:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8853:Tenm3	UTSW	8	48,342,347 (GRCm38)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,236,402 (GRCm38)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,235,602 (GRCm38)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,279,060 (GRCm38)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,235,348 (GRCm38)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,276,687 (GRCm38)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,342,653 (GRCm38)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,254,633 (GRCm38)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,292,151 (GRCm38)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,335,513 (GRCm38)	missense	unknown
R9231:Tenm3	UTSW	8	48,236,196 (GRCm38)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	48,555,900 (GRCm38)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,417,080 (GRCm38)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,299,655 (GRCm38)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	48,674,524 (GRCm38)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,313,257 (GRCm38)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,235,761 (GRCm38)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,236,211 (GRCm38)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,300,814 (GRCm38)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,335,561 (GRCm38)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,287,829 (GRCm38)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,236,477 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,276,780 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TCCATCGACGTCGTACTCGTAC -3'
(R):5'- GACAGATTTTCCGCTTCAGC -3'

Sequencing Primer
(F):5'- ACTCGTACGCGTATTTGGTAG -3'
(R):5'- GCTTCAGCGAGGATGGAATG -3'

Posted On

2014-08-25