Incidental Mutation 'R1971:Thada'
| ID |
220987 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
039984-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1971 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 84617470 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Threonine
at position 1349
(P1349T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047524
AA Change: P1349T
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: P1349T
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Meta Mutation Damage Score |
0.2332 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.3%
|
| Validation Efficiency |
99% (115/116) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700001O22Rik |
A |
T |
2: 30,686,566 (GRCm39) |
I242N |
probably benign |
Het |
| 2510009E07Rik |
G |
T |
16: 21,472,048 (GRCm39) |
Y217* |
probably null |
Het |
| 4931429L15Rik |
C |
T |
9: 46,220,086 (GRCm39) |
V149M |
probably benign |
Het |
| Abcg8 |
G |
T |
17: 85,002,587 (GRCm39) |
|
probably benign |
Het |
| Acox1 |
A |
G |
11: 116,089,087 (GRCm39) |
F77S |
probably benign |
Het |
| Adgrb3 |
G |
T |
1: 25,586,525 (GRCm39) |
H389Q |
probably benign |
Het |
| Ak7 |
A |
G |
12: 105,692,504 (GRCm39) |
N186S |
probably damaging |
Het |
| Apobr |
A |
G |
7: 126,185,397 (GRCm39) |
T303A |
probably benign |
Het |
| Arnt |
C |
T |
3: 95,355,704 (GRCm39) |
S16L |
possibly damaging |
Het |
| Bcl9l |
T |
C |
9: 44,419,996 (GRCm39) |
|
probably null |
Het |
| Bco2 |
T |
C |
9: 50,457,284 (GRCm39) |
D86G |
probably damaging |
Het |
| Bmpr1b |
T |
A |
3: 141,563,333 (GRCm39) |
I204F |
probably damaging |
Het |
| Bpifb5 |
C |
A |
2: 154,072,264 (GRCm39) |
Q324K |
probably benign |
Het |
| Cacna2d2 |
G |
A |
9: 107,389,205 (GRCm39) |
V223I |
probably damaging |
Het |
| Capn3 |
A |
G |
2: 120,311,228 (GRCm39) |
D105G |
possibly damaging |
Het |
| Ccdc40 |
G |
T |
11: 119,153,901 (GRCm39) |
|
probably null |
Het |
| Ccdc83 |
T |
A |
7: 89,893,362 (GRCm39) |
S132C |
probably damaging |
Het |
| Ckap2l |
A |
G |
2: 129,127,342 (GRCm39) |
S279P |
possibly damaging |
Het |
| Cldn12 |
C |
A |
5: 5,558,137 (GRCm39) |
A97S |
probably benign |
Het |
| Clec2l |
T |
G |
6: 38,640,309 (GRCm39) |
S47A |
probably benign |
Het |
| Csnk1d |
C |
A |
11: 120,863,274 (GRCm39) |
R222M |
possibly damaging |
Het |
| Ctnna1 |
T |
A |
18: 35,287,580 (GRCm39) |
D96E |
probably benign |
Het |
| D630045J12Rik |
T |
C |
6: 38,145,078 (GRCm39) |
D1316G |
probably damaging |
Het |
| Ddx4 |
C |
T |
13: 112,736,547 (GRCm39) |
V608I |
probably damaging |
Het |
| Dmtf1 |
T |
C |
5: 9,198,989 (GRCm39) |
E48G |
probably benign |
Het |
| Dnah17 |
G |
C |
11: 117,995,361 (GRCm39) |
Q996E |
probably benign |
Het |
| Dnah9 |
G |
C |
11: 65,739,197 (GRCm39) |
N4180K |
probably damaging |
Het |
| Dpf3 |
T |
A |
12: 83,371,809 (GRCm39) |
|
probably null |
Het |
| Drd2 |
T |
C |
9: 49,318,359 (GRCm39) |
F434L |
probably damaging |
Het |
| En1 |
A |
G |
1: 120,534,742 (GRCm39) |
T344A |
unknown |
Het |
| Eri3 |
A |
G |
4: 117,421,964 (GRCm39) |
T81A |
probably benign |
Het |
| Fam20a |
T |
C |
11: 109,576,237 (GRCm39) |
Y174C |
probably damaging |
Het |
| Fam234a |
G |
C |
17: 26,435,629 (GRCm39) |
|
probably null |
Het |
| Fam76a |
A |
T |
4: 132,631,294 (GRCm39) |
I217N |
probably damaging |
Het |
| Fancm |
T |
A |
12: 65,148,466 (GRCm39) |
S694T |
probably benign |
Het |
| Fcgbpl1 |
C |
A |
7: 27,830,937 (GRCm39) |
A50E |
possibly damaging |
Het |
| Foxo3 |
A |
G |
10: 42,073,258 (GRCm39) |
S420P |
probably benign |
Het |
| Foxp4 |
C |
T |
17: 48,186,796 (GRCm39) |
R378Q |
unknown |
Het |
| Gm136 |
T |
G |
4: 34,755,986 (GRCm39) |
D9A |
probably benign |
Het |
| Gstt2 |
G |
T |
10: 75,668,499 (GRCm39) |
T116N |
probably benign |
Het |
| Hs3st6 |
A |
G |
17: 24,972,267 (GRCm39) |
T70A |
probably benign |
Het |
| Hspa14 |
A |
G |
2: 3,490,804 (GRCm39) |
V461A |
possibly damaging |
Het |
| Itih5 |
A |
T |
2: 10,243,379 (GRCm39) |
D372V |
probably damaging |
Het |
| Kcna2 |
A |
T |
3: 107,012,140 (GRCm39) |
R240S |
probably damaging |
Het |
| Kctd18 |
T |
C |
1: 58,006,779 (GRCm39) |
I24V |
probably benign |
Het |
| Lap3 |
T |
C |
5: 45,663,508 (GRCm39) |
|
probably benign |
Het |
| Lcp1 |
T |
C |
14: 75,437,946 (GRCm39) |
S119P |
probably damaging |
Het |
| Lig3 |
G |
C |
11: 82,686,544 (GRCm39) |
D642H |
probably benign |
Het |
| Lpin1 |
A |
T |
12: 16,630,724 (GRCm39) |
L58H |
probably damaging |
Het |
| Map4k5 |
G |
T |
12: 69,873,102 (GRCm39) |
P468Q |
possibly damaging |
Het |
| Med31 |
G |
A |
11: 72,106,244 (GRCm39) |
|
probably benign |
Het |
| Mki67 |
A |
T |
7: 135,315,688 (GRCm39) |
|
probably null |
Het |
| Mrc1 |
G |
A |
2: 14,249,103 (GRCm39) |
|
probably null |
Het |
| Msh3 |
A |
G |
13: 92,359,784 (GRCm39) |
I16T |
probably damaging |
Het |
| Msh3 |
T |
A |
13: 92,386,328 (GRCm39) |
|
probably benign |
Het |
| Mst1r |
A |
T |
9: 107,790,411 (GRCm39) |
I675F |
probably benign |
Het |
| Myb |
A |
C |
10: 21,016,555 (GRCm39) |
S652A |
probably benign |
Het |
| Myh2 |
G |
T |
11: 67,080,004 (GRCm39) |
S1099I |
possibly damaging |
Het |
| Myl6b |
A |
G |
10: 128,330,512 (GRCm39) |
V181A |
probably damaging |
Het |
| Myt1l |
A |
T |
12: 29,877,091 (GRCm39) |
K247N |
unknown |
Het |
| Nanos2 |
G |
T |
7: 18,721,629 (GRCm39) |
V34L |
probably benign |
Het |
| Nav1 |
T |
C |
1: 135,460,091 (GRCm39) |
T411A |
probably benign |
Het |
| Nedd9 |
T |
A |
13: 41,492,424 (GRCm39) |
I23F |
probably damaging |
Het |
| Nes |
G |
A |
3: 87,885,634 (GRCm39) |
V1254I |
possibly damaging |
Het |
| Nol6 |
A |
G |
4: 41,119,542 (GRCm39) |
F588S |
probably damaging |
Het |
| Numa1 |
C |
T |
7: 101,658,529 (GRCm39) |
A1605V |
probably damaging |
Het |
| Ofd1 |
T |
C |
X: 165,210,210 (GRCm39) |
Y205C |
probably benign |
Het |
| Olr1 |
T |
C |
6: 129,470,498 (GRCm39) |
E223G |
probably benign |
Het |
| Or1e30 |
T |
A |
11: 73,678,616 (GRCm39) |
M284K |
probably damaging |
Het |
| Or2ag12 |
T |
A |
7: 106,276,877 (GRCm39) |
N272I |
probably damaging |
Het |
| Or4c118 |
A |
T |
2: 88,975,078 (GRCm39) |
C96* |
probably null |
Het |
| Or51k2 |
A |
T |
7: 103,596,150 (GRCm39) |
I126F |
probably damaging |
Het |
| Or51l4 |
C |
T |
7: 103,404,527 (GRCm39) |
W88* |
probably null |
Het |
| Pate6 |
T |
A |
9: 35,700,309 (GRCm39) |
H92L |
probably benign |
Het |
| Pclo |
A |
G |
5: 14,763,487 (GRCm39) |
T3987A |
unknown |
Het |
| Pik3cg |
A |
T |
12: 32,242,152 (GRCm39) |
V986D |
probably damaging |
Het |
| Pitpnm1 |
T |
A |
19: 4,162,450 (GRCm39) |
D1093E |
probably damaging |
Het |
| Ppp1r12b |
T |
C |
1: 134,793,651 (GRCm39) |
D571G |
probably benign |
Het |
| Rfx1 |
A |
G |
8: 84,822,126 (GRCm39) |
E875G |
probably damaging |
Het |
| Rnf145 |
T |
A |
11: 44,439,642 (GRCm39) |
I146N |
probably damaging |
Het |
| Rttn |
G |
A |
18: 89,108,557 (GRCm39) |
R1587H |
probably benign |
Het |
| Safb |
A |
G |
17: 56,912,821 (GRCm39) |
H883R |
probably benign |
Het |
| Sdhb |
A |
G |
4: 140,700,260 (GRCm39) |
D120G |
possibly damaging |
Het |
| Serpine3 |
A |
G |
14: 62,902,533 (GRCm39) |
N48S |
probably damaging |
Het |
| Sgms1 |
T |
A |
19: 32,137,357 (GRCm39) |
I70L |
probably benign |
Het |
| Slc1a7 |
G |
T |
4: 107,825,782 (GRCm39) |
D14Y |
probably benign |
Het |
| Smtnl2 |
C |
T |
11: 72,302,183 (GRCm39) |
A93T |
probably benign |
Het |
| Srpra |
T |
C |
9: 35,124,834 (GRCm39) |
|
probably null |
Het |
| Taf6l |
A |
G |
19: 8,752,866 (GRCm39) |
|
probably null |
Het |
| Tbc1d10b |
A |
T |
7: 126,807,036 (GRCm39) |
V167E |
probably benign |
Het |
| Tbc1d9 |
G |
A |
8: 83,976,139 (GRCm39) |
R566H |
probably damaging |
Het |
| Tenm3 |
A |
G |
8: 48,689,348 (GRCm39) |
Y2080H |
probably damaging |
Het |
| Tex14 |
A |
G |
11: 87,402,431 (GRCm39) |
N506S |
probably damaging |
Het |
| Tjp1 |
G |
T |
7: 64,973,826 (GRCm39) |
T476K |
probably damaging |
Het |
| Tlr11 |
A |
T |
14: 50,598,691 (GRCm39) |
T226S |
probably benign |
Het |
| Tmem131 |
G |
A |
1: 36,843,680 (GRCm39) |
Q1394* |
probably null |
Het |
| Tmem161a |
C |
T |
8: 70,629,559 (GRCm39) |
R58W |
probably damaging |
Het |
| Tmem219 |
T |
C |
7: 126,496,422 (GRCm39) |
S13G |
probably benign |
Het |
| Trp53bp1 |
T |
C |
2: 121,035,517 (GRCm39) |
Y47C |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,731,922 (GRCm39) |
|
probably benign |
Het |
| Ush1g |
A |
G |
11: 115,209,280 (GRCm39) |
S305P |
probably damaging |
Het |
| Usp37 |
A |
T |
1: 74,479,127 (GRCm39) |
Y948* |
probably null |
Het |
| Vav1 |
A |
T |
17: 57,634,697 (GRCm39) |
Y805F |
probably damaging |
Het |
| Vmn1r59 |
A |
T |
7: 5,457,038 (GRCm39) |
Y241N |
probably damaging |
Het |
| Vmn2r2 |
T |
A |
3: 64,034,121 (GRCm39) |
Y467F |
probably damaging |
Het |
| Vps35l |
A |
C |
7: 118,374,557 (GRCm39) |
R352S |
probably damaging |
Het |
| Vps54 |
C |
A |
11: 21,242,051 (GRCm39) |
L389I |
probably damaging |
Het |
| Vwa8 |
G |
T |
14: 79,162,694 (GRCm39) |
|
probably benign |
Het |
| Wdr19 |
G |
T |
5: 65,398,503 (GRCm39) |
|
probably benign |
Het |
| Wnt2b |
A |
T |
3: 104,861,933 (GRCm39) |
|
probably benign |
Het |
| Xirp2 |
A |
G |
2: 67,342,039 (GRCm39) |
R1427G |
possibly damaging |
Het |
| Ylpm1 |
T |
C |
12: 85,087,560 (GRCm39) |
S1115P |
probably damaging |
Het |
| Zfp946 |
T |
A |
17: 22,674,406 (GRCm39) |
C387S |
probably damaging |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,723,731 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,533,432 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,766,283 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,751,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,533,469 (GRCm39) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,736,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTCACACAGAGCTGTTGTAC -3'
(R):5'- TCAAGTCAGTTTTGCTATCACCTG -3'
Sequencing Primer
(F):5'- GTACTTACTTGCAGAAGTGTCCCATG -3'
(R):5'- AGTCAGTTTTGCTATCACCTGTTATC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation