Mutagenetix > Incidental Mutation

Incidental Mutation 'R2044:Nbeal1'

221556

Institutional Source

Beutler Lab

Gene Symbol

Nbeal1

Ensembl Gene

ENSMUSG00000073664

Gene Name

neurobeachin like 1

Synonyms

A530083I02Rik, A530050O19Rik, ALS2CR17, 2310076G13Rik

MMRRC Submission

040051-MU

Accession Numbers

Genbank: NM_173444; MGI: 2444343

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2044 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

60180599-60338328 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 60319687 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Lysine at position 1176 (I1176K)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160834] [ENSMUST00000162291]

AlphaFold

E9PYP2

Predicted Effect

probably damaging
Transcript: ENSMUST00000035569
AA Change: I1176K

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000049393
Gene: ENSMUSG00000073664
AA Change: I1176K

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
low complexity region	719	735	N/A	INTRINSIC
Pfam:DUF4704	851	1130	3.4e-39	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
Pfam:DUF4800	1575	1828	6.3e-126	PFAM
coiled coil region	1859	1882	N/A	INTRINSIC
Pfam:PH_BEACH	1889	1975	2e-24	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000160834
AA Change: I2512K

PolyPhen 2 Score 0.875 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000124056
Gene: ENSMUSG00000073664
AA Change: I2512K

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
Pfam:Laminin_G_3	567	801	8.3e-9	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
low complexity region	1849	1865	N/A	INTRINSIC
Pfam:PH_BEACH	1882	1975	4.9e-32	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000162291

SMART Domains

Protein: ENSMUSP00000125592
Gene: ENSMUSG00000073664

Domain	Start	End	E-Value	Type
low complexity region	114	132	N/A	INTRINSIC
low complexity region	580	596	N/A	INTRINSIC
Pfam:PH_BEACH	613	706	9.6e-33	PFAM

Meta Mutation Damage Score

0.6988

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.8%
20x: 93.7%

Validation Efficiency

98% (92/94)

Allele List at MGI

All alleles(16) : Targeted(1) Gene trapped(15)

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410137M14Rik	G	A	17: 36,978,094 (GRCm38)		probably benign	Het
Abhd15	A	G	11: 77,518,338 (GRCm38)	T293A	probably benign	Het
Aldh1l1	C	T	6: 90,562,665 (GRCm38)	P192L	probably benign	Het
Aldoart1	T	G	4: 72,852,542 (GRCm38)	I10L	probably benign	Het
Ankhd1	G	A	18: 36,645,113 (GRCm38)	G1653D	probably benign	Het
Ankk1	A	C	9: 49,419,364 (GRCm38)		probably null	Het
Astn1	A	G	1: 158,600,502 (GRCm38)	T748A	possibly damaging	Het
Bmp7	C	A	2: 172,939,915 (GRCm38)	R52L	possibly damaging	Het
Ccdc151	T	G	9: 21,991,858 (GRCm38)	T419P	possibly damaging	Het
Ccdc33	G	A	9: 58,031,112 (GRCm38)	P859S	possibly damaging	Het
Ccny	A	G	18: 9,449,644 (GRCm38)	S10P	probably damaging	Het
Cdc6	C	A	11: 98,910,461 (GRCm38)	F179L	probably benign	Het
Cdc7	T	A	5: 106,983,132 (GRCm38)	V491E	probably benign	Het
Cdh23	G	T	10: 60,596,730 (GRCm38)	S138R	possibly damaging	Het
Cenpc1	T	C	5: 86,037,755 (GRCm38)	H299R	probably benign	Het
Ciart	A	T	3: 95,878,701 (GRCm38)	M354K	probably benign	Het
Clasrp	G	T	7: 19,586,715 (GRCm38)		probably benign	Het
Col4a3	G	A	1: 82,696,319 (GRCm38)	G1132E	unknown	Het
Crebbp	G	A	16: 4,084,823 (GRCm38)	T2184I	probably benign	Het
Cyp2r1	A	C	7: 114,550,405 (GRCm38)	M458R	probably damaging	Het
Cyp7a1	C	A	4: 6,275,492 (GRCm38)	R27M	probably null	Het
Ddhd2	A	G	8: 25,752,165 (GRCm38)	F116L	probably damaging	Het
Dgkd	G	A	1: 87,927,691 (GRCm38)	R685K	probably benign	Het
Dnah2	A	G	11: 69,524,240 (GRCm38)	S223P	probably benign	Het
Exph5	A	T	9: 53,372,679 (GRCm38)	R353S	possibly damaging	Het
F11	C	A	8: 45,252,118 (GRCm38)	V129F	probably benign	Het
F830045P16Rik	A	T	2: 129,459,397 (GRCm38)	S454T	possibly damaging	Het
Fam124a	T	C	14: 62,587,207 (GRCm38)	I50T	probably damaging	Het
Fam20c	T	C	5: 138,756,227 (GRCm38)		probably null	Het
Fam234b	A	G	6: 135,226,914 (GRCm38)	T405A	probably benign	Het
Fbxo18	C	A	2: 11,762,970 (GRCm38)	V356L	possibly damaging	Het
Flywch1	G	A	17: 23,762,313 (GRCm38)	Q132*	probably null	Het
Foxo6	T	C	4: 120,286,969 (GRCm38)	D95G	probably benign	Het
Ggt5	T	C	10: 75,604,087 (GRCm38)	F174S	probably damaging	Het
Gm7104	G	A	12: 88,285,781 (GRCm38)		noncoding transcript	Het
Gpr155	A	G	2: 73,373,633 (GRCm38)	L279P	probably damaging	Het
H2-T23	A	G	17: 36,032,191 (GRCm38)	L98P	probably damaging	Het
Heatr5a	A	G	12: 51,955,403 (GRCm38)	V250A	probably benign	Het
Heyl	A	T	4: 123,241,363 (GRCm38)	I50F	probably damaging	Het
Hist4h4	G	C	6: 136,804,103 (GRCm38)	R93G	possibly damaging	Het
Ifitm10	A	T	7: 142,356,034 (GRCm38)	S179R	probably damaging	Het
Isg15	A	T	4: 156,199,792 (GRCm38)	I93N	probably benign	Het
Itga10	G	A	3: 96,657,690 (GRCm38)	V985I	probably benign	Het
Itga10	C	T	3: 96,651,738 (GRCm38)		probably benign	Het
Kcnt2	T	C	1: 140,375,154 (GRCm38)	I144T	probably benign	Het
Klk1	A	C	7: 44,229,034 (GRCm38)	K104T	possibly damaging	Het
Lemd3	C	A	10: 120,933,442 (GRCm38)	R654L	probably damaging	Het
Lmod1	A	T	1: 135,364,387 (GRCm38)	M327L	probably benign	Het
Lonrf2	T	C	1: 38,807,050 (GRCm38)	E347G	probably benign	Het
Ltbp1	A	G	17: 75,276,432 (GRCm38)	Y409C	probably damaging	Het
Mecom	A	T	3: 29,980,592 (GRCm38)	Y312N	probably damaging	Het
Mrgprb3	C	T	7: 48,643,734 (GRCm38)	C23Y	possibly damaging	Het
Mut	A	G	17: 40,941,451 (GRCm38)	T295A	probably benign	Het
Nadk	C	A	4: 155,585,441 (GRCm38)	L194I	probably damaging	Het
Naxd	A	G	8: 11,509,510 (GRCm38)	I182V	probably benign	Het
Nol4l	C	A	2: 153,529,521 (GRCm38)	R81L	possibly damaging	Het
Olfr1297	T	A	2: 111,621,814 (GRCm38)	R87W	probably benign	Het
Olfr1411	G	T	1: 92,596,969 (GRCm38)	R150L	probably benign	Het
Olfr957	A	T	9: 39,511,378 (GRCm38)	M114K	probably damaging	Het
Pcdh18	A	G	3: 49,754,940 (GRCm38)	V642A	probably benign	Het
Pdzk1	G	A	3: 96,855,848 (GRCm38)		probably benign	Het
Per3	C	T	4: 151,033,938 (GRCm38)	V233I	probably benign	Het
Pisd	G	A	5: 32,764,796 (GRCm38)	P267S	possibly damaging	Het
Prm1	T	A	16: 10,796,493 (GRCm38)		probably benign	Het
Ptprj	A	G	2: 90,463,095 (GRCm38)	V548A	probably damaging	Het
Ranbp3	G	A	17: 56,673,367 (GRCm38)		probably benign	Het
Raver2	T	A	4: 101,102,812 (GRCm38)	V163D	probably damaging	Het
Rbm14	A	T	19: 4,803,877 (GRCm38)	I159N	possibly damaging	Het
Rfx6	G	A	10: 51,718,126 (GRCm38)	V381I	probably benign	Het
Rhobtb1	T	C	10: 69,272,863 (GRCm38)		probably benign	Het
Rpl28-ps4	T	A	6: 117,213,895 (GRCm38)		noncoding transcript	Het
Rsph10b	A	G	5: 143,967,250 (GRCm38)		probably null	Het
Rspo4	A	G	2: 151,873,093 (GRCm38)	K217E	unknown	Het
Scgb2b27	G	A	7: 34,013,285 (GRCm38)	A44V	possibly damaging	Het
Sec14l2	G	A	11: 4,111,435 (GRCm38)		probably benign	Het
Sec31b	T	C	19: 44,536,156 (GRCm38)	N101D	probably benign	Het
Sema6a	A	T	18: 47,306,429 (GRCm38)	C9*	probably null	Het
Sept5	A	C	16: 18,623,012 (GRCm38)	L331R	probably benign	Het
Slc16a11	C	A	11: 70,215,651 (GRCm38)	Y238*	probably null	Het
Slc25a12	T	C	2: 71,312,548 (GRCm38)	T210A	probably benign	Het
Slc35f1	A	T	10: 53,089,347 (GRCm38)	Y286F	probably damaging	Het
Szt2	A	T	4: 118,376,448 (GRCm38)	L2225*	probably null	Het
Thap12	T	C	7: 98,716,620 (GRCm38)	L665P	probably damaging	Het
Tpsb2	T	A	17: 25,367,724 (GRCm38)	W237R	probably damaging	Het
Tyk2	T	C	9: 21,120,341 (GRCm38)	D451G	probably damaging	Het
Ube2j1	T	A	4: 33,049,696 (GRCm38)	N231K	probably benign	Het
Vmn1r225	A	T	17: 20,502,590 (GRCm38)	T98S	possibly damaging	Het
Vmn1r87	A	T	7: 13,131,821 (GRCm38)	S180T	probably benign	Het
Vmn2r6	A	G	3: 64,537,841 (GRCm38)	V821A	probably damaging	Het
Zfp689	C	A	7: 127,444,826 (GRCm38)	G211C	probably damaging	Het
Zfp827	A	G	8: 79,076,236 (GRCm38)	D479G	probably benign	Het
Zfp995	A	C	17: 21,880,594 (GRCm38)	F220V	probably damaging	Het

Other mutations in Nbeal1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Nbeal1	APN	1	60,235,191 (GRCm38)	nonsense	probably null	0.00
IGL00334:Nbeal1	APN	1	60,281,883 (GRCm38)	missense	probably damaging	0.98
IGL00334:Nbeal1	APN	1	60,328,103 (GRCm38)	missense	probably damaging	1.00
IGL00514:Nbeal1	APN	1	60,217,225 (GRCm38)	missense	probably benign	0.31
IGL00596:Nbeal1	APN	1	60,181,741 (GRCm38)	missense	probably damaging	0.96
IGL00654:Nbeal1	APN	1	60,195,011 (GRCm38)	critical splice acceptor site	probably benign	0.00
IGL00757:Nbeal1	APN	1	60,195,143 (GRCm38)	missense	possibly damaging	0.82
IGL00771:Nbeal1	APN	1	60,235,353 (GRCm38)	missense	probably benign	0.11
IGL01315:Nbeal1	APN	1	60,281,341 (GRCm38)	missense	probably damaging	1.00
IGL01445:Nbeal1	APN	1	60,242,625 (GRCm38)	critical splice donor site	probably null
IGL01456:Nbeal1	APN	1	60,230,628 (GRCm38)	missense	probably damaging	1.00
IGL01458:Nbeal1	APN	1	60,242,625 (GRCm38)	critical splice donor site	probably null
IGL01535:Nbeal1	APN	1	60,217,255 (GRCm38)	missense	probably damaging	1.00
IGL01608:Nbeal1	APN	1	60,242,535 (GRCm38)	critical splice acceptor site	probably benign	0.00
IGL02006:Nbeal1	APN	1	60,272,259 (GRCm38)	critical splice donor site	probably null
IGL02105:Nbeal1	APN	1	60,253,501 (GRCm38)	missense	probably damaging	1.00
IGL02409:Nbeal1	APN	1	60,329,335 (GRCm38)	missense	probably benign	0.01
IGL02713:Nbeal1	APN	1	60,235,237 (GRCm38)	missense	possibly damaging	0.94
IGL02720:Nbeal1	APN	1	60,283,987 (GRCm38)	missense	probably damaging	0.98
IGL02887:Nbeal1	APN	1	60,287,444 (GRCm38)	splice site	probably benign
IGL02945:Nbeal1	APN	1	60,206,410 (GRCm38)	missense	probably damaging	1.00
IGL03023:Nbeal1	APN	1	60,253,413 (GRCm38)	missense	probably damaging	0.98
IGL03114:Nbeal1	APN	1	60,278,727 (GRCm38)	missense	probably damaging	1.00
IGL03231:Nbeal1	APN	1	60,236,459 (GRCm38)	missense	probably benign	0.44
IGL03241:Nbeal1	APN	1	60,234,868 (GRCm38)	missense	possibly damaging	0.46
IGL03241:Nbeal1	APN	1	60,234,869 (GRCm38)	missense	probably benign	0.44
IGL03382:Nbeal1	APN	1	60,261,586 (GRCm38)	critical splice donor site	probably null
IGL03412:Nbeal1	APN	1	60,242,567 (GRCm38)	nonsense	probably null
coach	UTSW	1	60,253,481 (GRCm38)	nonsense	probably null
Committee	UTSW	1	60,292,903 (GRCm38)	missense	probably damaging	1.00
Disgrace	UTSW	1	60,281,310 (GRCm38)	nonsense	probably null
Dravrah	UTSW	1	60,284,092 (GRCm38)	missense	probably damaging	1.00
Harvard	UTSW	1	60,235,563 (GRCm38)	splice site	probably null
horrified	UTSW	1	60,244,824 (GRCm38)	missense	probably damaging	1.00
Lampoon	UTSW	1	60,261,586 (GRCm38)	critical splice donor site	probably null
lawyer	UTSW	1	60,310,224 (GRCm38)	nonsense	probably null
magistrate	UTSW	1	60,194,597 (GRCm38)	critical splice donor site	probably null
Maratimus	UTSW	1	60,291,888 (GRCm38)	missense	probably damaging	1.00
National	UTSW	1	60,222,263 (GRCm38)	missense	possibly damaging	0.95
phainopepla	UTSW	1	60,319,687 (GRCm38)	missense	probably damaging	1.00
R3875_Nbeal1_770	UTSW	1	60,194,599 (GRCm38)	splice site	probably benign
satirical	UTSW	1	60,235,562 (GRCm38)	critical splice donor site	probably null
silky	UTSW	1	60,330,878 (GRCm38)	splice site	probably benign
stiggs	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
3-1:Nbeal1	UTSW	1	60,264,272 (GRCm38)	splice site	probably benign
P0007:Nbeal1	UTSW	1	60,319,688 (GRCm38)	missense	probably damaging	0.98
P0028:Nbeal1	UTSW	1	60,291,937 (GRCm38)	missense	probably damaging	1.00
R0041:Nbeal1	UTSW	1	60,281,871 (GRCm38)	missense	probably benign	0.05
R0051:Nbeal1	UTSW	1	60,310,263 (GRCm38)	missense	probably benign	0.19
R0052:Nbeal1	UTSW	1	60,228,612 (GRCm38)	splice site	probably benign
R0054:Nbeal1	UTSW	1	60,287,401 (GRCm38)	utr 3 prime	probably benign
R0062:Nbeal1	UTSW	1	60,247,717 (GRCm38)	missense	probably benign	0.01
R0062:Nbeal1	UTSW	1	60,247,717 (GRCm38)	missense	probably benign	0.01
R0094:Nbeal1	UTSW	1	60,305,309 (GRCm38)	missense	possibly damaging	0.62
R0310:Nbeal1	UTSW	1	60,305,370 (GRCm38)	splice site	probably benign
R0324:Nbeal1	UTSW	1	60,292,873 (GRCm38)	missense	probably damaging	1.00
R0329:Nbeal1	UTSW	1	60,268,063 (GRCm38)	missense	probably damaging	1.00
R0330:Nbeal1	UTSW	1	60,268,063 (GRCm38)	missense	probably damaging	1.00
R0417:Nbeal1	UTSW	1	60,247,734 (GRCm38)	missense	probably benign	0.00
R0421:Nbeal1	UTSW	1	60,268,439 (GRCm38)	missense	probably benign	0.08
R0617:Nbeal1	UTSW	1	60,281,832 (GRCm38)	nonsense	probably null
R1034:Nbeal1	UTSW	1	60,290,006 (GRCm38)	nonsense	probably null
R1082:Nbeal1	UTSW	1	60,312,226 (GRCm38)	missense	probably damaging	0.99
R1123:Nbeal1	UTSW	1	60,260,269 (GRCm38)	missense	probably benign
R1187:Nbeal1	UTSW	1	60,194,528 (GRCm38)	missense	probably damaging	1.00
R1484:Nbeal1	UTSW	1	60,200,939 (GRCm38)	missense	probably damaging	1.00
R1594:Nbeal1	UTSW	1	60,305,291 (GRCm38)	missense	possibly damaging	0.91
R1651:Nbeal1	UTSW	1	60,200,119 (GRCm38)	missense	probably damaging	1.00
R1678:Nbeal1	UTSW	1	60,260,334 (GRCm38)	missense	probably benign	0.00
R1806:Nbeal1	UTSW	1	60,284,092 (GRCm38)	missense	probably damaging	1.00
R1937:Nbeal1	UTSW	1	60,267,941 (GRCm38)	nonsense	probably null
R1952:Nbeal1	UTSW	1	60,234,840 (GRCm38)	missense	probably damaging	1.00
R1953:Nbeal1	UTSW	1	60,234,840 (GRCm38)	missense	probably damaging	1.00
R2038:Nbeal1	UTSW	1	60,206,344 (GRCm38)	missense	probably benign	0.00
R2050:Nbeal1	UTSW	1	60,292,964 (GRCm38)	splice site	probably null
R2055:Nbeal1	UTSW	1	60,311,057 (GRCm38)	missense	probably damaging	1.00
R2064:Nbeal1	UTSW	1	60,270,356 (GRCm38)	missense	possibly damaging	0.89
R2100:Nbeal1	UTSW	1	60,305,271 (GRCm38)	splice site	probably null
R2181:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R2192:Nbeal1	UTSW	1	60,281,895 (GRCm38)	missense	probably damaging	1.00
R2203:Nbeal1	UTSW	1	60,284,006 (GRCm38)	missense	probably benign	0.21
R2267:Nbeal1	UTSW	1	60,330,878 (GRCm38)	splice site	probably benign
R2268:Nbeal1	UTSW	1	60,330,878 (GRCm38)	splice site	probably benign
R2351:Nbeal1	UTSW	1	60,237,098 (GRCm38)	missense	possibly damaging	0.90
R2366:Nbeal1	UTSW	1	60,251,352 (GRCm38)	missense	probably damaging	0.97
R2393:Nbeal1	UTSW	1	60,251,370 (GRCm38)	missense	probably damaging	0.98
R3545:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R3546:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R3547:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R3701:Nbeal1	UTSW	1	60,251,413 (GRCm38)	splice site	probably benign
R3747:Nbeal1	UTSW	1	60,195,023 (GRCm38)	missense	probably damaging	0.98
R3875:Nbeal1	UTSW	1	60,194,599 (GRCm38)	splice site	probably benign
R4119:Nbeal1	UTSW	1	60,291,870 (GRCm38)	missense	probably damaging	0.99
R4256:Nbeal1	UTSW	1	60,330,948 (GRCm38)	missense	probably benign	0.19
R4371:Nbeal1	UTSW	1	60,289,946 (GRCm38)	missense	possibly damaging	0.95
R4450:Nbeal1	UTSW	1	60,267,774 (GRCm38)	missense	probably damaging	0.97
R4558:Nbeal1	UTSW	1	60,281,310 (GRCm38)	nonsense	probably null
R4618:Nbeal1	UTSW	1	60,228,731 (GRCm38)	intron	probably benign
R4673:Nbeal1	UTSW	1	60,329,390 (GRCm38)	missense	probably damaging	1.00
R4719:Nbeal1	UTSW	1	60,235,563 (GRCm38)	splice site	probably null
R4798:Nbeal1	UTSW	1	60,222,193 (GRCm38)	splice site	probably null
R4826:Nbeal1	UTSW	1	60,251,342 (GRCm38)	missense	possibly damaging	0.79
R4841:Nbeal1	UTSW	1	60,253,375 (GRCm38)	missense	probably damaging	1.00
R4842:Nbeal1	UTSW	1	60,253,375 (GRCm38)	missense	probably damaging	1.00
R4895:Nbeal1	UTSW	1	60,292,903 (GRCm38)	missense	probably damaging	1.00
R4929:Nbeal1	UTSW	1	60,238,654 (GRCm38)	missense	probably damaging	1.00
R5026:Nbeal1	UTSW	1	60,237,179 (GRCm38)	missense	probably damaging	1.00
R5243:Nbeal1	UTSW	1	60,270,328 (GRCm38)	missense	probably damaging	0.99
R5300:Nbeal1	UTSW	1	60,235,559 (GRCm38)	nonsense	probably null
R5345:Nbeal1	UTSW	1	60,328,210 (GRCm38)	critical splice donor site	probably null
R5502:Nbeal1	UTSW	1	60,310,999 (GRCm38)	missense	probably damaging	1.00
R5542:Nbeal1	UTSW	1	60,277,194 (GRCm38)	missense	probably benign	0.00
R5555:Nbeal1	UTSW	1	60,237,152 (GRCm38)	missense	possibly damaging	0.93
R5580:Nbeal1	UTSW	1	60,242,602 (GRCm38)	missense	probably benign	0.45
R5765:Nbeal1	UTSW	1	60,291,847 (GRCm38)	missense	probably damaging	1.00
R5802:Nbeal1	UTSW	1	60,272,221 (GRCm38)	missense	probably benign	0.01
R5907:Nbeal1	UTSW	1	60,228,791 (GRCm38)	intron	probably benign
R5918:Nbeal1	UTSW	1	60,267,892 (GRCm38)	missense	possibly damaging	0.90
R5923:Nbeal1	UTSW	1	60,248,395 (GRCm38)	missense	probably damaging	1.00
R6066:Nbeal1	UTSW	1	60,248,405 (GRCm38)	missense	probably benign	0.29
R6091:Nbeal1	UTSW	1	60,181,556 (GRCm38)	start gained	probably benign
R6113:Nbeal1	UTSW	1	60,222,263 (GRCm38)	missense	possibly damaging	0.95
R6143:Nbeal1	UTSW	1	60,251,307 (GRCm38)	missense	possibly damaging	0.81
R6194:Nbeal1	UTSW	1	60,257,484 (GRCm38)	missense	possibly damaging	0.80
R6197:Nbeal1	UTSW	1	60,222,128 (GRCm38)	missense	probably damaging	0.99
R6228:Nbeal1	UTSW	1	60,295,924 (GRCm38)	missense	probably benign	0.00
R6229:Nbeal1	UTSW	1	60,248,365 (GRCm38)	missense	possibly damaging	0.88
R6309:Nbeal1	UTSW	1	60,238,719 (GRCm38)	missense	probably benign
R6457:Nbeal1	UTSW	1	60,253,474 (GRCm38)	missense	probably benign	0.31
R6489:Nbeal1	UTSW	1	60,330,942 (GRCm38)	missense	possibly damaging	0.89
R6845:Nbeal1	UTSW	1	60,281,310 (GRCm38)	nonsense	probably null
R7021:Nbeal1	UTSW	1	60,261,586 (GRCm38)	critical splice donor site	probably null
R7033:Nbeal1	UTSW	1	60,310,947 (GRCm38)	missense	probably damaging	1.00
R7144:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7145:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7146:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7157:Nbeal1	UTSW	1	60,260,634 (GRCm38)	nonsense	probably null
R7157:Nbeal1	UTSW	1	60,237,158 (GRCm38)	missense	probably damaging	1.00
R7209:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7210:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7211:Nbeal1	UTSW	1	60,200,951 (GRCm38)	missense	probably damaging	1.00
R7212:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7213:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7214:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7283:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7285:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7287:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7296:Nbeal1	UTSW	1	60,310,224 (GRCm38)	nonsense	probably null
R7312:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7313:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7329:Nbeal1	UTSW	1	60,217,196 (GRCm38)	missense	probably benign	0.39
R7380:Nbeal1	UTSW	1	60,244,810 (GRCm38)	missense	probably damaging	1.00
R7414:Nbeal1	UTSW	1	60,194,597 (GRCm38)	critical splice donor site	probably null
R7477:Nbeal1	UTSW	1	60,261,584 (GRCm38)	missense	probably benign
R7507:Nbeal1	UTSW	1	60,235,467 (GRCm38)	missense	probably damaging	1.00
R7642:Nbeal1	UTSW	1	60,277,227 (GRCm38)	missense	probably benign	0.31
R7678:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7689:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7728:Nbeal1	UTSW	1	60,244,824 (GRCm38)	missense	probably damaging	1.00
R7757:Nbeal1	UTSW	1	60,257,450 (GRCm38)	missense	probably damaging	0.97
R7761:Nbeal1	UTSW	1	60,319,341 (GRCm38)	missense	probably benign	0.00
R7813:Nbeal1	UTSW	1	60,291,889 (GRCm38)	missense	probably damaging	1.00
R7829:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7891:Nbeal1	UTSW	1	60,260,432 (GRCm38)	missense	probably benign
R7902:Nbeal1	UTSW	1	60,291,870 (GRCm38)	missense	probably damaging	0.99
R8022:Nbeal1	UTSW	1	60,260,272 (GRCm38)	nonsense	probably null
R8053:Nbeal1	UTSW	1	60,279,795 (GRCm38)	missense	probably damaging	0.98
R8169:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8170:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8178:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8182:Nbeal1	UTSW	1	60,200,133 (GRCm38)	missense	probably benign	0.00
R8186:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8187:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8193:Nbeal1	UTSW	1	60,253,481 (GRCm38)	nonsense	probably null
R8209:Nbeal1	UTSW	1	60,277,177 (GRCm38)	missense	probably damaging	0.99
R8226:Nbeal1	UTSW	1	60,277,177 (GRCm38)	missense	probably damaging	0.99
R8549:Nbeal1	UTSW	1	60,235,562 (GRCm38)	critical splice donor site	probably null
R8560:Nbeal1	UTSW	1	60,235,157 (GRCm38)	missense	probably benign	0.38
R8753:Nbeal1	UTSW	1	60,268,383 (GRCm38)	missense	probably damaging	1.00
R8769:Nbeal1	UTSW	1	60,235,211 (GRCm38)	missense	probably damaging	0.99
R8771:Nbeal1	UTSW	1	60,261,584 (GRCm38)	missense	probably benign
R8952:Nbeal1	UTSW	1	60,260,300 (GRCm38)	missense	probably benign	0.01
R9014:Nbeal1	UTSW	1	60,289,959 (GRCm38)	missense	probably damaging	1.00
R9056:Nbeal1	UTSW	1	60,278,726 (GRCm38)	missense	probably damaging	1.00
R9091:Nbeal1	UTSW	1	60,268,389 (GRCm38)	missense	possibly damaging	0.50
R9138:Nbeal1	UTSW	1	60,247,745 (GRCm38)	nonsense	probably null
R9168:Nbeal1	UTSW	1	60,291,888 (GRCm38)	missense	probably damaging	1.00
R9200:Nbeal1	UTSW	1	60,281,266 (GRCm38)	missense	probably damaging	1.00
R9205:Nbeal1	UTSW	1	60,278,680 (GRCm38)	missense	probably damaging	1.00
R9270:Nbeal1	UTSW	1	60,268,389 (GRCm38)	missense	possibly damaging	0.50
R9322:Nbeal1	UTSW	1	60,258,659 (GRCm38)	missense	possibly damaging	0.91
R9405:Nbeal1	UTSW	1	60,310,265 (GRCm38)	missense	probably damaging	1.00
R9554:Nbeal1	UTSW	1	60,251,128 (GRCm38)	nonsense	probably null
R9557:Nbeal1	UTSW	1	60,235,350 (GRCm38)	missense	probably benign
R9560:Nbeal1	UTSW	1	60,329,385 (GRCm38)	missense	probably damaging	1.00
R9641:Nbeal1	UTSW	1	60,311,088 (GRCm38)	missense	probably damaging	1.00
R9784:Nbeal1	UTSW	1	60,260,582 (GRCm38)	nonsense	probably null
X0022:Nbeal1	UTSW	1	60,277,232 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GTTTCTGGCATGAAAATAGGGG -3'
(R):5'- TGCCTCTGTAGTGTGGAAAG -3'

Sequencing Primer
(F):5'- GGATCTTATTGGCCTTATGAG -3'
(R):5'- GGACTGTCTATACCTACTGCAGAG -3'

Posted On

2014-08-25