Incidental Mutation 'R2044:Ptprj'
| ID |
221576 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ptprj
|
| Ensembl Gene |
ENSMUSG00000025314 |
| Gene Name |
protein tyrosine phosphatase, receptor type, J |
| Synonyms |
CD148, Byp, Scc1, Scc-1, DEP-1, RPTPJ |
| MMRRC Submission |
040051-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.167)
|
| Stock # |
R2044 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
90429754-90580647 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 90463095 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 548
(V548A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000129592
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000111493]
[ENSMUST00000111495]
[ENSMUST00000168621]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111493
AA Change: V362A
PolyPhen 2
Score 0.798 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000107119
Gene: ENSMUSG00000025314
AA Change: V362A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
46 |
N/A |
INTRINSIC |
|
FN3
|
47 |
182 |
3.76e-6 |
SMART |
|
FN3
|
194 |
271 |
4.56e-5 |
SMART |
|
FN3
|
282 |
357 |
5.32e-6 |
SMART |
|
FN3
|
368 |
446 |
2.19e-7 |
SMART |
|
FN3
|
455 |
531 |
5e-2 |
SMART |
|
FN3
|
546 |
628 |
2.77e1 |
SMART |
|
low complexity region
|
637 |
650 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
714 |
797 |
8e-26 |
BLAST |
|
PTPc
|
867 |
1127 |
3.37e-133 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000111495
AA Change: V455A
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000107121
Gene: ENSMUSG00000025314
AA Change: V455A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
25 |
N/A |
INTRINSIC |
|
FN3
|
59 |
131 |
2.85e-6 |
SMART |
|
FN3
|
140 |
275 |
3.76e-6 |
SMART |
|
FN3
|
287 |
364 |
4.56e-5 |
SMART |
|
FN3
|
375 |
450 |
5.32e-6 |
SMART |
|
FN3
|
461 |
539 |
2.19e-7 |
SMART |
|
FN3
|
548 |
624 |
5e-2 |
SMART |
|
FN3
|
639 |
721 |
2.77e1 |
SMART |
|
low complexity region
|
730 |
743 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
807 |
890 |
1e-25 |
BLAST |
|
PTPc
|
960 |
1220 |
3.37e-133 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000168621
AA Change: V548A
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000129592
Gene: ENSMUSG00000025314
AA Change: V548A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
94 |
N/A |
INTRINSIC |
|
low complexity region
|
133 |
140 |
N/A |
INTRINSIC |
|
FN3
|
152 |
224 |
2.85e-6 |
SMART |
|
FN3
|
233 |
368 |
3.76e-6 |
SMART |
|
FN3
|
380 |
457 |
4.56e-5 |
SMART |
|
FN3
|
468 |
543 |
5.32e-6 |
SMART |
|
FN3
|
554 |
632 |
2.19e-7 |
SMART |
|
FN3
|
641 |
717 |
5e-2 |
SMART |
|
FN3
|
732 |
814 |
2.77e1 |
SMART |
|
low complexity region
|
823 |
836 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
900 |
983 |
1e-25 |
BLAST |
|
PTPc
|
1053 |
1313 |
3.37e-133 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.7%
|
| Validation Efficiency |
98% (92/94) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null allele die in utero displaying severe growth retardation and cardiovascular defects. Homozygotes for a second null allele are viable, fertile and healthy with no spontaneous tumor formation. Homozygotes for a third null allele show sterility and a block B cell development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2410137M14Rik |
G |
A |
17: 36,978,094 (GRCm38) |
|
probably benign |
Het |
| Abhd15 |
A |
G |
11: 77,518,338 (GRCm38) |
T293A |
probably benign |
Het |
| Aldh1l1 |
C |
T |
6: 90,562,665 (GRCm38) |
P192L |
probably benign |
Het |
| Aldoart1 |
T |
G |
4: 72,852,542 (GRCm38) |
I10L |
probably benign |
Het |
| Ankhd1 |
G |
A |
18: 36,645,113 (GRCm38) |
G1653D |
probably benign |
Het |
| Ankk1 |
A |
C |
9: 49,419,364 (GRCm38) |
|
probably null |
Het |
| Astn1 |
A |
G |
1: 158,600,502 (GRCm38) |
T748A |
possibly damaging |
Het |
| Bmp7 |
C |
A |
2: 172,939,915 (GRCm38) |
R52L |
possibly damaging |
Het |
| Ccdc151 |
T |
G |
9: 21,991,858 (GRCm38) |
T419P |
possibly damaging |
Het |
| Ccdc33 |
G |
A |
9: 58,031,112 (GRCm38) |
P859S |
possibly damaging |
Het |
| Ccny |
A |
G |
18: 9,449,644 (GRCm38) |
S10P |
probably damaging |
Het |
| Cdc6 |
C |
A |
11: 98,910,461 (GRCm38) |
F179L |
probably benign |
Het |
| Cdc7 |
T |
A |
5: 106,983,132 (GRCm38) |
V491E |
probably benign |
Het |
| Cdh23 |
G |
T |
10: 60,596,730 (GRCm38) |
S138R |
possibly damaging |
Het |
| Cenpc1 |
T |
C |
5: 86,037,755 (GRCm38) |
H299R |
probably benign |
Het |
| Ciart |
A |
T |
3: 95,878,701 (GRCm38) |
M354K |
probably benign |
Het |
| Clasrp |
G |
T |
7: 19,586,715 (GRCm38) |
|
probably benign |
Het |
| Col4a3 |
G |
A |
1: 82,696,319 (GRCm38) |
G1132E |
unknown |
Het |
| Crebbp |
G |
A |
16: 4,084,823 (GRCm38) |
T2184I |
probably benign |
Het |
| Cyp2r1 |
A |
C |
7: 114,550,405 (GRCm38) |
M458R |
probably damaging |
Het |
| Cyp7a1 |
C |
A |
4: 6,275,492 (GRCm38) |
R27M |
probably null |
Het |
| Ddhd2 |
A |
G |
8: 25,752,165 (GRCm38) |
F116L |
probably damaging |
Het |
| Dgkd |
G |
A |
1: 87,927,691 (GRCm38) |
R685K |
probably benign |
Het |
| Dnah2 |
A |
G |
11: 69,524,240 (GRCm38) |
S223P |
probably benign |
Het |
| Exph5 |
A |
T |
9: 53,372,679 (GRCm38) |
R353S |
possibly damaging |
Het |
| F11 |
C |
A |
8: 45,252,118 (GRCm38) |
V129F |
probably benign |
Het |
| F830045P16Rik |
A |
T |
2: 129,459,397 (GRCm38) |
S454T |
possibly damaging |
Het |
| Fam124a |
T |
C |
14: 62,587,207 (GRCm38) |
I50T |
probably damaging |
Het |
| Fam20c |
T |
C |
5: 138,756,227 (GRCm38) |
|
probably null |
Het |
| Fam234b |
A |
G |
6: 135,226,914 (GRCm38) |
T405A |
probably benign |
Het |
| Fbxo18 |
C |
A |
2: 11,762,970 (GRCm38) |
V356L |
possibly damaging |
Het |
| Flywch1 |
G |
A |
17: 23,762,313 (GRCm38) |
Q132* |
probably null |
Het |
| Foxo6 |
T |
C |
4: 120,286,969 (GRCm38) |
D95G |
probably benign |
Het |
| Ggt5 |
T |
C |
10: 75,604,087 (GRCm38) |
F174S |
probably damaging |
Het |
| Gm7104 |
G |
A |
12: 88,285,781 (GRCm38) |
|
noncoding transcript |
Het |
| Gpr155 |
A |
G |
2: 73,373,633 (GRCm38) |
L279P |
probably damaging |
Het |
| H2-T23 |
A |
G |
17: 36,032,191 (GRCm38) |
L98P |
probably damaging |
Het |
| Heatr5a |
A |
G |
12: 51,955,403 (GRCm38) |
V250A |
probably benign |
Het |
| Heyl |
A |
T |
4: 123,241,363 (GRCm38) |
I50F |
probably damaging |
Het |
| Hist4h4 |
G |
C |
6: 136,804,103 (GRCm38) |
R93G |
possibly damaging |
Het |
| Ifitm10 |
A |
T |
7: 142,356,034 (GRCm38) |
S179R |
probably damaging |
Het |
| Isg15 |
A |
T |
4: 156,199,792 (GRCm38) |
I93N |
probably benign |
Het |
| Itga10 |
G |
A |
3: 96,657,690 (GRCm38) |
V985I |
probably benign |
Het |
| Itga10 |
C |
T |
3: 96,651,738 (GRCm38) |
|
probably benign |
Het |
| Kcnt2 |
T |
C |
1: 140,375,154 (GRCm38) |
I144T |
probably benign |
Het |
| Klk1 |
A |
C |
7: 44,229,034 (GRCm38) |
K104T |
possibly damaging |
Het |
| Lemd3 |
C |
A |
10: 120,933,442 (GRCm38) |
R654L |
probably damaging |
Het |
| Lmod1 |
A |
T |
1: 135,364,387 (GRCm38) |
M327L |
probably benign |
Het |
| Lonrf2 |
T |
C |
1: 38,807,050 (GRCm38) |
E347G |
probably benign |
Het |
| Ltbp1 |
A |
G |
17: 75,276,432 (GRCm38) |
Y409C |
probably damaging |
Het |
| Mecom |
A |
T |
3: 29,980,592 (GRCm38) |
Y312N |
probably damaging |
Het |
| Mrgprb3 |
C |
T |
7: 48,643,734 (GRCm38) |
C23Y |
possibly damaging |
Het |
| Mut |
A |
G |
17: 40,941,451 (GRCm38) |
T295A |
probably benign |
Het |
| Nadk |
C |
A |
4: 155,585,441 (GRCm38) |
L194I |
probably damaging |
Het |
| Naxd |
A |
G |
8: 11,509,510 (GRCm38) |
I182V |
probably benign |
Het |
| Nbeal1 |
T |
A |
1: 60,319,687 (GRCm38) |
I1176K |
probably damaging |
Het |
| Nol4l |
C |
A |
2: 153,529,521 (GRCm38) |
R81L |
possibly damaging |
Het |
| Olfr1297 |
T |
A |
2: 111,621,814 (GRCm38) |
R87W |
probably benign |
Het |
| Olfr1411 |
G |
T |
1: 92,596,969 (GRCm38) |
R150L |
probably benign |
Het |
| Olfr957 |
A |
T |
9: 39,511,378 (GRCm38) |
M114K |
probably damaging |
Het |
| Pcdh18 |
A |
G |
3: 49,754,940 (GRCm38) |
V642A |
probably benign |
Het |
| Pdzk1 |
G |
A |
3: 96,855,848 (GRCm38) |
|
probably benign |
Het |
| Per3 |
C |
T |
4: 151,033,938 (GRCm38) |
V233I |
probably benign |
Het |
| Pisd |
G |
A |
5: 32,764,796 (GRCm38) |
P267S |
possibly damaging |
Het |
| Prm1 |
T |
A |
16: 10,796,493 (GRCm38) |
|
probably benign |
Het |
| Ranbp3 |
G |
A |
17: 56,673,367 (GRCm38) |
|
probably benign |
Het |
| Raver2 |
T |
A |
4: 101,102,812 (GRCm38) |
V163D |
probably damaging |
Het |
| Rbm14 |
A |
T |
19: 4,803,877 (GRCm38) |
I159N |
possibly damaging |
Het |
| Rfx6 |
G |
A |
10: 51,718,126 (GRCm38) |
V381I |
probably benign |
Het |
| Rhobtb1 |
T |
C |
10: 69,272,863 (GRCm38) |
|
probably benign |
Het |
| Rpl28-ps4 |
T |
A |
6: 117,213,895 (GRCm38) |
|
noncoding transcript |
Het |
| Rsph10b |
A |
G |
5: 143,967,250 (GRCm38) |
|
probably null |
Het |
| Rspo4 |
A |
G |
2: 151,873,093 (GRCm38) |
K217E |
unknown |
Het |
| Scgb2b27 |
G |
A |
7: 34,013,285 (GRCm38) |
A44V |
possibly damaging |
Het |
| Sec14l2 |
G |
A |
11: 4,111,435 (GRCm38) |
|
probably benign |
Het |
| Sec31b |
T |
C |
19: 44,536,156 (GRCm38) |
N101D |
probably benign |
Het |
| Sema6a |
A |
T |
18: 47,306,429 (GRCm38) |
C9* |
probably null |
Het |
| Sept5 |
A |
C |
16: 18,623,012 (GRCm38) |
L331R |
probably benign |
Het |
| Slc16a11 |
C |
A |
11: 70,215,651 (GRCm38) |
Y238* |
probably null |
Het |
| Slc25a12 |
T |
C |
2: 71,312,548 (GRCm38) |
T210A |
probably benign |
Het |
| Slc35f1 |
A |
T |
10: 53,089,347 (GRCm38) |
Y286F |
probably damaging |
Het |
| Szt2 |
A |
T |
4: 118,376,448 (GRCm38) |
L2225* |
probably null |
Het |
| Thap12 |
T |
C |
7: 98,716,620 (GRCm38) |
L665P |
probably damaging |
Het |
| Tpsb2 |
T |
A |
17: 25,367,724 (GRCm38) |
W237R |
probably damaging |
Het |
| Tyk2 |
T |
C |
9: 21,120,341 (GRCm38) |
D451G |
probably damaging |
Het |
| Ube2j1 |
T |
A |
4: 33,049,696 (GRCm38) |
N231K |
probably benign |
Het |
| Vmn1r225 |
A |
T |
17: 20,502,590 (GRCm38) |
T98S |
possibly damaging |
Het |
| Vmn1r87 |
A |
T |
7: 13,131,821 (GRCm38) |
S180T |
probably benign |
Het |
| Vmn2r6 |
A |
G |
3: 64,537,841 (GRCm38) |
V821A |
probably damaging |
Het |
| Zfp689 |
C |
A |
7: 127,444,826 (GRCm38) |
G211C |
probably damaging |
Het |
| Zfp827 |
A |
G |
8: 79,076,236 (GRCm38) |
D479G |
probably benign |
Het |
| Zfp995 |
A |
C |
17: 21,880,594 (GRCm38) |
F220V |
probably damaging |
Het |
|
| Other mutations in Ptprj |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01528:Ptprj
|
APN |
2 |
90,452,144 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01594:Ptprj
|
APN |
2 |
90,440,795 (GRCm38) |
splice site |
probably benign |
|
|
IGL01767:Ptprj
|
APN |
2 |
90,469,574 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL01917:Ptprj
|
APN |
2 |
90,469,749 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01981:Ptprj
|
APN |
2 |
90,439,912 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02830:Ptprj
|
APN |
2 |
90,453,144 (GRCm38) |
missense |
probably benign |
0.22 |
|
IGL02955:Ptprj
|
APN |
2 |
90,468,464 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
IGL03102:Ptprj
|
APN |
2 |
90,478,968 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL03150:Ptprj
|
APN |
2 |
90,460,611 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL03210:Ptprj
|
APN |
2 |
90,469,726 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02799:Ptprj
|
UTSW |
2 |
90,469,598 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0083:Ptprj
|
UTSW |
2 |
90,469,777 (GRCm38) |
splice site |
probably null |
|
|
R0108:Ptprj
|
UTSW |
2 |
90,469,777 (GRCm38) |
splice site |
probably null |
|
|
R0579:Ptprj
|
UTSW |
2 |
90,436,569 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R1130:Ptprj
|
UTSW |
2 |
90,453,421 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1160:Ptprj
|
UTSW |
2 |
90,444,524 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1238:Ptprj
|
UTSW |
2 |
90,444,414 (GRCm38) |
splice site |
probably null |
|
|
R1507:Ptprj
|
UTSW |
2 |
90,471,287 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R1552:Ptprj
|
UTSW |
2 |
90,471,153 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1607:Ptprj
|
UTSW |
2 |
90,463,320 (GRCm38) |
missense |
probably benign |
0.14 |
|
R1693:Ptprj
|
UTSW |
2 |
90,449,797 (GRCm38) |
nonsense |
probably null |
|
|
R2016:Ptprj
|
UTSW |
2 |
90,464,614 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2017:Ptprj
|
UTSW |
2 |
90,464,614 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2322:Ptprj
|
UTSW |
2 |
90,471,129 (GRCm38) |
missense |
probably benign |
0.06 |
|
R2516:Ptprj
|
UTSW |
2 |
90,474,996 (GRCm38) |
splice site |
probably benign |
|
|
R3106:Ptprj
|
UTSW |
2 |
90,440,631 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3964:Ptprj
|
UTSW |
2 |
90,468,441 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4201:Ptprj
|
UTSW |
2 |
90,463,095 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4533:Ptprj
|
UTSW |
2 |
90,439,955 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4680:Ptprj
|
UTSW |
2 |
90,460,496 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4738:Ptprj
|
UTSW |
2 |
90,440,643 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4983:Ptprj
|
UTSW |
2 |
90,460,532 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5137:Ptprj
|
UTSW |
2 |
90,469,648 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5349:Ptprj
|
UTSW |
2 |
90,471,261 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5369:Ptprj
|
UTSW |
2 |
90,469,641 (GRCm38) |
missense |
probably benign |
0.09 |
|
R5718:Ptprj
|
UTSW |
2 |
90,458,269 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5914:Ptprj
|
UTSW |
2 |
90,453,340 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R6022:Ptprj
|
UTSW |
2 |
90,471,323 (GRCm38) |
missense |
probably benign |
0.14 |
|
R6341:Ptprj
|
UTSW |
2 |
90,458,349 (GRCm38) |
missense |
probably benign |
|
|
R6421:Ptprj
|
UTSW |
2 |
90,471,140 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R6724:Ptprj
|
UTSW |
2 |
90,450,851 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6831:Ptprj
|
UTSW |
2 |
90,460,647 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6939:Ptprj
|
UTSW |
2 |
90,459,514 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R6972:Ptprj
|
UTSW |
2 |
90,580,403 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R7134:Ptprj
|
UTSW |
2 |
90,464,478 (GRCm38) |
missense |
probably benign |
0.16 |
|
R7149:Ptprj
|
UTSW |
2 |
90,444,446 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7243:Ptprj
|
UTSW |
2 |
90,446,421 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7335:Ptprj
|
UTSW |
2 |
90,440,782 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7439:Ptprj
|
UTSW |
2 |
90,449,819 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7441:Ptprj
|
UTSW |
2 |
90,449,819 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7498:Ptprj
|
UTSW |
2 |
90,436,565 (GRCm38) |
nonsense |
probably null |
|
|
R7571:Ptprj
|
UTSW |
2 |
90,455,186 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7657:Ptprj
|
UTSW |
2 |
90,452,157 (GRCm38) |
splice site |
probably null |
|
|
R7672:Ptprj
|
UTSW |
2 |
90,460,596 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R7849:Ptprj
|
UTSW |
2 |
90,444,460 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7939:Ptprj
|
UTSW |
2 |
90,464,665 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7958:Ptprj
|
UTSW |
2 |
90,469,627 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R8338:Ptprj
|
UTSW |
2 |
90,471,137 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R8354:Ptprj
|
UTSW |
2 |
90,469,717 (GRCm38) |
missense |
probably benign |
0.43 |
|
R8556:Ptprj
|
UTSW |
2 |
90,440,700 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8695:Ptprj
|
UTSW |
2 |
90,471,137 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R8784:Ptprj
|
UTSW |
2 |
90,460,512 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R8984:Ptprj
|
UTSW |
2 |
90,440,643 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9054:Ptprj
|
UTSW |
2 |
90,460,640 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9056:Ptprj
|
UTSW |
2 |
90,458,269 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9147:Ptprj
|
UTSW |
2 |
90,458,218 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9148:Ptprj
|
UTSW |
2 |
90,458,218 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9168:Ptprj
|
UTSW |
2 |
90,464,572 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R9314:Ptprj
|
UTSW |
2 |
90,471,287 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R9337:Ptprj
|
UTSW |
2 |
90,439,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9546:Ptprj
|
UTSW |
2 |
90,444,461 (GRCm38) |
missense |
probably benign |
0.08 |
|
RF013:Ptprj
|
UTSW |
2 |
90,471,170 (GRCm38) |
nonsense |
probably null |
|
|
Z1177:Ptprj
|
UTSW |
2 |
90,460,569 (GRCm38) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCAAGACAGCCAGGTTTG -3'
(R):5'- GCAATGACTCCAAGTCCTTCG -3'
Sequencing Primer
(F):5'- GACTCTAATCTTAGCACCTGAGAGG -3'
(R):5'- CCTTCGAGATTTTCATCAAGCAGGAC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation