Mutagenetix > Incidental Mutation

Incidental Mutation 'R2044:Ankhd1'

221741

Institutional Source

Beutler Lab

Gene Symbol

Ankhd1

Ensembl Gene

ENSMUSG00000024483

Gene Name

ankyrin repeat and KH domain containing 1

Synonyms

MMRRC Submission

040051-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2044 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

36559987-36665917 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 36645113 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Aspartic acid at position 1653 (G1653D)

Ref Sequence

ENSEMBL: ENSMUSP00000120290 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000006205] [ENSMUST00000142977] [ENSMUST00000155329]

AlphaFold

E9PUR0

Predicted Effect

probably benign
Transcript: ENSMUST00000006205
AA Change: G1653D

PolyPhen 2 Score 0.315 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000006205
Gene: ENSMUSG00000024483
AA Change: G1653D

Domain	Start	End	E-Value	Type
low complexity region	20	38	N/A	INTRINSIC
low complexity region	48	78	N/A	INTRINSIC
low complexity region	91	109	N/A	INTRINSIC
ANK	207	236	2.11e2	SMART
ANK	240	269	3.31e-1	SMART
ANK	274	303	5.24e-4	SMART
ANK	307	336	7.64e-6	SMART
ANK	340	369	2.7e-6	SMART
ANK	374	403	3.23e-4	SMART
ANK	407	436	1.61e-4	SMART
ANK	440	469	5.16e-3	SMART
ANK	473	502	4.16e-7	SMART
ANK	507	536	1.68e-2	SMART
ANK	537	566	7.02e-5	SMART
ANK	570	599	7.95e-4	SMART
ANK	603	632	4.56e-4	SMART
ANK	637	666	9.64e-3	SMART
ANK	670	699	6.71e-2	SMART
coiled coil region	815	855	N/A	INTRINSIC
ANK	1057	1086	2.07e-2	SMART
ANK	1090	1119	2.48e-5	SMART
ANK	1124	1153	3.85e-2	SMART
ANK	1157	1186	1.61e-4	SMART
ANK	1192	1221	1.24e-5	SMART
ANK	1226	1255	1.59e-3	SMART
ANK	1259	1288	3.91e-3	SMART
ANK	1294	1323	5.93e-3	SMART
ANK	1327	1356	9.41e-6	SMART
ANK	1360	1393	3.8e-1	SMART
coiled coil region	1422	1486	N/A	INTRINSIC
low complexity region	1509	1526	N/A	INTRINSIC
low complexity region	1538	1557	N/A	INTRINSIC
low complexity region	1585	1604	N/A	INTRINSIC
KH	1693	1763	5.04e-13	SMART
low complexity region	1968	2001	N/A	INTRINSIC
low complexity region	2041	2057	N/A	INTRINSIC
low complexity region	2064	2081	N/A	INTRINSIC
low complexity region	2334	2346	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000037072
AA Change: G142D

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000040300
Gene: ENSMUSG00000024483
AA Change: G142D

Domain	Start	End	E-Value	Type
low complexity region	1	16	N/A	INTRINSIC
low complexity region	28	47	N/A	INTRINSIC
low complexity region	75	94	N/A	INTRINSIC
KH	183	253	5.04e-13	SMART
low complexity region	458	491	N/A	INTRINSIC
low complexity region	531	547	N/A	INTRINSIC
low complexity region	554	571	N/A	INTRINSIC
low complexity region	824	836	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000130035

SMART Domains

Protein: ENSMUSP00000117110
Gene: ENSMUSG00000024483

Domain	Start	End	E-Value	Type
ANK	2	26	5.35e2	SMART
ANK	30	59	9.41e-6	SMART
ANK	63	96	3.8e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000140061

SMART Domains

Protein: ENSMUSP00000121811
Gene: ENSMUSG00000024483

Domain	Start	End	E-Value	Type
low complexity region	54	70	N/A	INTRINSIC
low complexity region	77	94	N/A	INTRINSIC
low complexity region	355	375	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000142977
AA Change: G1653D

PolyPhen 2 Score 0.315 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000120290
Gene: ENSMUSG00000024483
AA Change: G1653D

Domain	Start	End	E-Value	Type
low complexity region	20	38	N/A	INTRINSIC
low complexity region	48	78	N/A	INTRINSIC
low complexity region	91	109	N/A	INTRINSIC
ANK	207	236	2.11e2	SMART
ANK	240	269	3.31e-1	SMART
ANK	274	303	5.24e-4	SMART
ANK	307	336	7.64e-6	SMART
ANK	340	369	2.7e-6	SMART
ANK	374	403	3.23e-4	SMART
ANK	407	436	1.61e-4	SMART
ANK	440	469	5.16e-3	SMART
ANK	473	502	4.16e-7	SMART
ANK	507	536	1.68e-2	SMART
ANK	537	566	7.02e-5	SMART
ANK	570	599	7.95e-4	SMART
ANK	603	632	4.56e-4	SMART
ANK	637	666	9.64e-3	SMART
ANK	670	699	6.71e-2	SMART
coiled coil region	815	855	N/A	INTRINSIC
ANK	1057	1086	2.07e-2	SMART
ANK	1090	1119	2.48e-5	SMART
ANK	1124	1153	3.85e-2	SMART
ANK	1157	1186	1.61e-4	SMART
ANK	1192	1221	1.24e-5	SMART
ANK	1226	1255	1.59e-3	SMART
ANK	1259	1288	3.91e-3	SMART
ANK	1294	1323	5.93e-3	SMART
ANK	1327	1356	9.41e-6	SMART
ANK	1360	1393	3.8e-1	SMART
coiled coil region	1422	1486	N/A	INTRINSIC
low complexity region	1509	1526	N/A	INTRINSIC
low complexity region	1538	1557	N/A	INTRINSIC
low complexity region	1585	1604	N/A	INTRINSIC
KH	1693	1763	5.04e-13	SMART
low complexity region	1968	2001	N/A	INTRINSIC
low complexity region	2041	2057	N/A	INTRINSIC
low complexity region	2064	2081	N/A	INTRINSIC
low complexity region	2334	2346	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000152940

Predicted Effect

probably benign
Transcript: ENSMUST00000153612

SMART Domains

Protein: ENSMUSP00000116462
Gene: ENSMUSG00000024483

Domain	Start	End	E-Value	Type
ANK	10	39	9.41e-6	SMART
ANK	43	76	3.8e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000155329
AA Change: G1653D

PolyPhen 2 Score 0.112 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000123270
Gene: ENSMUSG00000024483
AA Change: G1653D

Domain	Start	End	E-Value	Type
low complexity region	20	38	N/A	INTRINSIC
low complexity region	48	78	N/A	INTRINSIC
low complexity region	91	109	N/A	INTRINSIC
ANK	207	236	2.11e2	SMART
ANK	240	269	3.31e-1	SMART
ANK	274	303	5.24e-4	SMART
ANK	307	336	7.64e-6	SMART
ANK	340	369	2.7e-6	SMART
ANK	374	403	3.23e-4	SMART
ANK	407	436	1.61e-4	SMART
ANK	440	469	5.16e-3	SMART
ANK	473	502	4.16e-7	SMART
ANK	507	536	1.68e-2	SMART
ANK	537	566	7.02e-5	SMART
ANK	570	599	7.95e-4	SMART
ANK	603	632	4.56e-4	SMART
ANK	637	666	9.64e-3	SMART
ANK	670	699	6.71e-2	SMART
coiled coil region	815	855	N/A	INTRINSIC
ANK	1057	1086	2.07e-2	SMART
ANK	1090	1119	2.48e-5	SMART
ANK	1124	1153	3.85e-2	SMART
ANK	1157	1186	1.61e-4	SMART
ANK	1192	1221	1.24e-5	SMART
ANK	1226	1255	1.59e-3	SMART
ANK	1259	1288	3.91e-3	SMART
ANK	1294	1323	5.93e-3	SMART
ANK	1327	1356	9.41e-6	SMART
ANK	1360	1393	3.8e-1	SMART
coiled coil region	1422	1486	N/A	INTRINSIC
low complexity region	1509	1526	N/A	INTRINSIC
low complexity region	1538	1557	N/A	INTRINSIC
low complexity region	1585	1604	N/A	INTRINSIC
KH	1693	1763	5.04e-13	SMART
low complexity region	1968	2001	N/A	INTRINSIC
low complexity region	2041	2057	N/A	INTRINSIC
low complexity region	2064	2081	N/A	INTRINSIC
low complexity region	2342	2362	N/A	INTRINSIC

Meta Mutation Damage Score

0.0592

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.8%
20x: 93.7%

Validation Efficiency

98% (92/94)

Allele List at MGI

Other mutations in this stock

Total: 92 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410137M14Rik	G	A	17: 36,978,094 (GRCm38)		probably benign	Het
Abhd15	A	G	11: 77,518,338 (GRCm38)	T293A	probably benign	Het
Aldh1l1	C	T	6: 90,562,665 (GRCm38)	P192L	probably benign	Het
Aldoart1	T	G	4: 72,852,542 (GRCm38)	I10L	probably benign	Het
Ankk1	A	C	9: 49,419,364 (GRCm38)		probably null	Het
Astn1	A	G	1: 158,600,502 (GRCm38)	T748A	possibly damaging	Het
Bmp7	C	A	2: 172,939,915 (GRCm38)	R52L	possibly damaging	Het
Ccdc151	T	G	9: 21,991,858 (GRCm38)	T419P	possibly damaging	Het
Ccdc33	G	A	9: 58,031,112 (GRCm38)	P859S	possibly damaging	Het
Ccny	A	G	18: 9,449,644 (GRCm38)	S10P	probably damaging	Het
Cdc6	C	A	11: 98,910,461 (GRCm38)	F179L	probably benign	Het
Cdc7	T	A	5: 106,983,132 (GRCm38)	V491E	probably benign	Het
Cdh23	G	T	10: 60,596,730 (GRCm38)	S138R	possibly damaging	Het
Cenpc1	T	C	5: 86,037,755 (GRCm38)	H299R	probably benign	Het
Ciart	A	T	3: 95,878,701 (GRCm38)	M354K	probably benign	Het
Clasrp	G	T	7: 19,586,715 (GRCm38)		probably benign	Het
Col4a3	G	A	1: 82,696,319 (GRCm38)	G1132E	unknown	Het
Crebbp	G	A	16: 4,084,823 (GRCm38)	T2184I	probably benign	Het
Cyp2r1	A	C	7: 114,550,405 (GRCm38)	M458R	probably damaging	Het
Cyp7a1	C	A	4: 6,275,492 (GRCm38)	R27M	probably null	Het
Ddhd2	A	G	8: 25,752,165 (GRCm38)	F116L	probably damaging	Het
Dgkd	G	A	1: 87,927,691 (GRCm38)	R685K	probably benign	Het
Dnah2	A	G	11: 69,524,240 (GRCm38)	S223P	probably benign	Het
Exph5	A	T	9: 53,372,679 (GRCm38)	R353S	possibly damaging	Het
F11	C	A	8: 45,252,118 (GRCm38)	V129F	probably benign	Het
F830045P16Rik	A	T	2: 129,459,397 (GRCm38)	S454T	possibly damaging	Het
Fam124a	T	C	14: 62,587,207 (GRCm38)	I50T	probably damaging	Het
Fam20c	T	C	5: 138,756,227 (GRCm38)		probably null	Het
Fam234b	A	G	6: 135,226,914 (GRCm38)	T405A	probably benign	Het
Fbxo18	C	A	2: 11,762,970 (GRCm38)	V356L	possibly damaging	Het
Flywch1	G	A	17: 23,762,313 (GRCm38)	Q132*	probably null	Het
Foxo6	T	C	4: 120,286,969 (GRCm38)	D95G	probably benign	Het
Ggt5	T	C	10: 75,604,087 (GRCm38)	F174S	probably damaging	Het
Gm7104	G	A	12: 88,285,781 (GRCm38)		noncoding transcript	Het
Gpr155	A	G	2: 73,373,633 (GRCm38)	L279P	probably damaging	Het
H2-T23	A	G	17: 36,032,191 (GRCm38)	L98P	probably damaging	Het
Heatr5a	A	G	12: 51,955,403 (GRCm38)	V250A	probably benign	Het
Heyl	A	T	4: 123,241,363 (GRCm38)	I50F	probably damaging	Het
Hist4h4	G	C	6: 136,804,103 (GRCm38)	R93G	possibly damaging	Het
Ifitm10	A	T	7: 142,356,034 (GRCm38)	S179R	probably damaging	Het
Isg15	A	T	4: 156,199,792 (GRCm38)	I93N	probably benign	Het
Itga10	G	A	3: 96,657,690 (GRCm38)	V985I	probably benign	Het
Itga10	C	T	3: 96,651,738 (GRCm38)		probably benign	Het
Kcnt2	T	C	1: 140,375,154 (GRCm38)	I144T	probably benign	Het
Klk1	A	C	7: 44,229,034 (GRCm38)	K104T	possibly damaging	Het
Lemd3	C	A	10: 120,933,442 (GRCm38)	R654L	probably damaging	Het
Lmod1	A	T	1: 135,364,387 (GRCm38)	M327L	probably benign	Het
Lonrf2	T	C	1: 38,807,050 (GRCm38)	E347G	probably benign	Het
Ltbp1	A	G	17: 75,276,432 (GRCm38)	Y409C	probably damaging	Het
Mecom	A	T	3: 29,980,592 (GRCm38)	Y312N	probably damaging	Het
Mrgprb3	C	T	7: 48,643,734 (GRCm38)	C23Y	possibly damaging	Het
Mut	A	G	17: 40,941,451 (GRCm38)	T295A	probably benign	Het
Nadk	C	A	4: 155,585,441 (GRCm38)	L194I	probably damaging	Het
Naxd	A	G	8: 11,509,510 (GRCm38)	I182V	probably benign	Het
Nbeal1	T	A	1: 60,319,687 (GRCm38)	I1176K	probably damaging	Het
Nol4l	C	A	2: 153,529,521 (GRCm38)	R81L	possibly damaging	Het
Olfr1297	T	A	2: 111,621,814 (GRCm38)	R87W	probably benign	Het
Olfr1411	G	T	1: 92,596,969 (GRCm38)	R150L	probably benign	Het
Olfr957	A	T	9: 39,511,378 (GRCm38)	M114K	probably damaging	Het
Pcdh18	A	G	3: 49,754,940 (GRCm38)	V642A	probably benign	Het
Pdzk1	G	A	3: 96,855,848 (GRCm38)		probably benign	Het
Per3	C	T	4: 151,033,938 (GRCm38)	V233I	probably benign	Het
Pisd	G	A	5: 32,764,796 (GRCm38)	P267S	possibly damaging	Het
Prm1	T	A	16: 10,796,493 (GRCm38)		probably benign	Het
Ptprj	A	G	2: 90,463,095 (GRCm38)	V548A	probably damaging	Het
Ranbp3	G	A	17: 56,673,367 (GRCm38)		probably benign	Het
Raver2	T	A	4: 101,102,812 (GRCm38)	V163D	probably damaging	Het
Rbm14	A	T	19: 4,803,877 (GRCm38)	I159N	possibly damaging	Het
Rfx6	G	A	10: 51,718,126 (GRCm38)	V381I	probably benign	Het
Rhobtb1	T	C	10: 69,272,863 (GRCm38)		probably benign	Het
Rpl28-ps4	T	A	6: 117,213,895 (GRCm38)		noncoding transcript	Het
Rsph10b	A	G	5: 143,967,250 (GRCm38)		probably null	Het
Rspo4	A	G	2: 151,873,093 (GRCm38)	K217E	unknown	Het
Scgb2b27	G	A	7: 34,013,285 (GRCm38)	A44V	possibly damaging	Het
Sec14l2	G	A	11: 4,111,435 (GRCm38)		probably benign	Het
Sec31b	T	C	19: 44,536,156 (GRCm38)	N101D	probably benign	Het
Sema6a	A	T	18: 47,306,429 (GRCm38)	C9*	probably null	Het
Sept5	A	C	16: 18,623,012 (GRCm38)	L331R	probably benign	Het
Slc16a11	C	A	11: 70,215,651 (GRCm38)	Y238*	probably null	Het
Slc25a12	T	C	2: 71,312,548 (GRCm38)	T210A	probably benign	Het
Slc35f1	A	T	10: 53,089,347 (GRCm38)	Y286F	probably damaging	Het
Szt2	A	T	4: 118,376,448 (GRCm38)	L2225*	probably null	Het
Thap12	T	C	7: 98,716,620 (GRCm38)	L665P	probably damaging	Het
Tpsb2	T	A	17: 25,367,724 (GRCm38)	W237R	probably damaging	Het
Tyk2	T	C	9: 21,120,341 (GRCm38)	D451G	probably damaging	Het
Ube2j1	T	A	4: 33,049,696 (GRCm38)	N231K	probably benign	Het
Vmn1r225	A	T	17: 20,502,590 (GRCm38)	T98S	possibly damaging	Het
Vmn1r87	A	T	7: 13,131,821 (GRCm38)	S180T	probably benign	Het
Vmn2r6	A	G	3: 64,537,841 (GRCm38)	V821A	probably damaging	Het
Zfp689	C	A	7: 127,444,826 (GRCm38)	G211C	probably damaging	Het
Zfp827	A	G	8: 79,076,236 (GRCm38)	D479G	probably benign	Het
Zfp995	A	C	17: 21,880,594 (GRCm38)	F220V	probably damaging	Het

Other mutations in Ankhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Ankhd1	APN	18	36,665,459 (GRCm38)	unclassified	probably benign
IGL00927:Ankhd1	APN	18	36,632,072 (GRCm38)	missense	probably benign	0.01
IGL01367:Ankhd1	APN	18	36,578,643 (GRCm38)	missense	probably benign	0.16
IGL01624:Ankhd1	APN	18	36,658,013 (GRCm38)	missense	probably damaging	1.00
IGL01725:Ankhd1	APN	18	36,648,153 (GRCm38)	missense	probably benign	0.04
IGL01767:Ankhd1	APN	18	36,648,374 (GRCm38)	missense	probably damaging	1.00
IGL02005:Ankhd1	APN	18	36,648,426 (GRCm38)	missense	probably damaging	1.00
IGL02009:Ankhd1	APN	18	36,624,661 (GRCm38)	missense	probably damaging	1.00
IGL02246:Ankhd1	APN	18	36,656,726 (GRCm38)	missense	probably damaging	1.00
IGL02336:Ankhd1	APN	18	36,594,814 (GRCm38)	missense	probably damaging	0.97
IGL02628:Ankhd1	APN	18	36,647,703 (GRCm38)	missense	probably benign	0.00
IGL02644:Ankhd1	APN	18	36,578,775 (GRCm38)	critical splice donor site	probably null
IGL02735:Ankhd1	APN	18	36,648,546 (GRCm38)	missense	probably benign	0.00
IGL02877:Ankhd1	APN	18	36,594,823 (GRCm38)	missense	probably damaging	1.00
IGL03129:Ankhd1	APN	18	36,658,008 (GRCm38)	nonsense	probably null
IGL03163:Ankhd1	APN	18	36,647,628 (GRCm38)	missense	probably damaging	0.97
IGL03182:Ankhd1	APN	18	36,578,774 (GRCm38)	missense	probably benign	0.06
IGL03184:Ankhd1	APN	18	36,647,777 (GRCm38)	missense	probably damaging	1.00
IGL03398:Ankhd1	APN	18	36,656,837 (GRCm38)	splice site	probably benign
FR4304:Ankhd1	UTSW	18	36,560,924 (GRCm38)	small insertion	probably benign
R0051:Ankhd1	UTSW	18	36,647,188 (GRCm38)	unclassified	probably benign
R0089:Ankhd1	UTSW	18	36,640,356 (GRCm38)	missense	probably damaging	0.99
R0105:Ankhd1	UTSW	18	36,646,766 (GRCm38)	missense	probably damaging	1.00
R0149:Ankhd1	UTSW	18	36,647,214 (GRCm38)	missense	probably damaging	1.00
R0243:Ankhd1	UTSW	18	36,634,734 (GRCm38)	missense	probably damaging	1.00
R0322:Ankhd1	UTSW	18	36,658,008 (GRCm38)	nonsense	probably null
R0361:Ankhd1	UTSW	18	36,647,214 (GRCm38)	missense	probably damaging	1.00
R0389:Ankhd1	UTSW	18	36,644,599 (GRCm38)	missense	possibly damaging	0.48
R0418:Ankhd1	UTSW	18	36,634,300 (GRCm38)	missense	probably damaging	1.00
R0443:Ankhd1	UTSW	18	36,644,599 (GRCm38)	missense	possibly damaging	0.48
R0540:Ankhd1	UTSW	18	36,640,280 (GRCm38)	missense	probably damaging	1.00
R0607:Ankhd1	UTSW	18	36,640,280 (GRCm38)	missense	probably damaging	1.00
R0738:Ankhd1	UTSW	18	36,645,249 (GRCm38)	splice site	probably benign
R1127:Ankhd1	UTSW	18	36,634,346 (GRCm38)	missense	probably damaging	1.00
R1434:Ankhd1	UTSW	18	36,625,159 (GRCm38)	missense	probably benign	0.09
R1742:Ankhd1	UTSW	18	36,625,265 (GRCm38)	missense	probably damaging	1.00
R1776:Ankhd1	UTSW	18	36,647,308 (GRCm38)	missense	probably benign	0.17
R1856:Ankhd1	UTSW	18	36,644,527 (GRCm38)	missense	probably benign	0.00
R1923:Ankhd1	UTSW	18	36,648,030 (GRCm38)	missense	probably benign	0.08
R2112:Ankhd1	UTSW	18	36,641,626 (GRCm38)	missense	probably damaging	1.00
R2115:Ankhd1	UTSW	18	36,634,308 (GRCm38)	missense	probably damaging	1.00
R2136:Ankhd1	UTSW	18	36,647,621 (GRCm38)	missense	probably benign
R2196:Ankhd1	UTSW	18	36,648,379 (GRCm38)	missense	probably damaging	1.00
R2291:Ankhd1	UTSW	18	36,644,333 (GRCm38)	missense	probably benign	0.31
R2305:Ankhd1	UTSW	18	36,642,926 (GRCm38)	missense	possibly damaging	0.59
R2309:Ankhd1	UTSW	18	36,624,765 (GRCm38)	missense	probably damaging	1.00
R2519:Ankhd1	UTSW	18	36,578,543 (GRCm38)	splice site	probably null
R2958:Ankhd1	UTSW	18	36,634,729 (GRCm38)	missense	probably damaging	1.00
R3978:Ankhd1	UTSW	18	36,647,613 (GRCm38)	missense	probably damaging	0.96
R3980:Ankhd1	UTSW	18	36,647,613 (GRCm38)	missense	probably damaging	0.96
R4159:Ankhd1	UTSW	18	36,589,540 (GRCm38)	missense	possibly damaging	0.91
R4199:Ankhd1	UTSW	18	36,661,048 (GRCm38)	unclassified	probably benign
R4323:Ankhd1	UTSW	18	36,578,633 (GRCm38)	missense	probably damaging	1.00
R4356:Ankhd1	UTSW	18	36,643,043 (GRCm38)	nonsense	probably null
R4496:Ankhd1	UTSW	18	36,560,786 (GRCm38)	missense	probably damaging	0.98
R4551:Ankhd1	UTSW	18	36,655,507 (GRCm38)	splice site	probably null
R4590:Ankhd1	UTSW	18	36,583,644 (GRCm38)	missense	probably damaging	1.00
R4667:Ankhd1	UTSW	18	36,648,021 (GRCm38)	missense	possibly damaging	0.77
R4889:Ankhd1	UTSW	18	36,578,734 (GRCm38)	missense	probably null	0.00
R4923:Ankhd1	UTSW	18	36,589,452 (GRCm38)	missense	probably damaging	1.00
R5091:Ankhd1	UTSW	18	36,625,027 (GRCm38)	missense	possibly damaging	0.68
R5254:Ankhd1	UTSW	18	36,656,715 (GRCm38)	missense	probably benign	0.05
R5314:Ankhd1	UTSW	18	36,561,058 (GRCm38)	splice site	probably null
R5336:Ankhd1	UTSW	18	36,646,716 (GRCm38)	missense	probably damaging	1.00
R5367:Ankhd1	UTSW	18	36,589,408 (GRCm38)	missense	probably damaging	1.00
R5384:Ankhd1	UTSW	18	36,591,495 (GRCm38)	missense	probably damaging	1.00
R5385:Ankhd1	UTSW	18	36,591,495 (GRCm38)	missense	probably damaging	1.00
R5387:Ankhd1	UTSW	18	36,634,644 (GRCm38)	missense	probably damaging	1.00
R5458:Ankhd1	UTSW	18	36,648,485 (GRCm38)	missense	probably benign	0.01
R5599:Ankhd1	UTSW	18	36,560,807 (GRCm38)	missense	probably damaging	0.98
R5659:Ankhd1	UTSW	18	36,561,050 (GRCm38)	missense	probably damaging	1.00
R5750:Ankhd1	UTSW	18	36,624,902 (GRCm38)	missense	probably benign	0.00
R5874:Ankhd1	UTSW	18	36,640,269 (GRCm38)	missense	possibly damaging	0.92
R5894:Ankhd1	UTSW	18	36,647,524 (GRCm38)	missense	probably damaging	0.99
R5969:Ankhd1	UTSW	18	36,600,834 (GRCm38)	missense	probably damaging	1.00
R6133:Ankhd1	UTSW	18	36,625,126 (GRCm38)	missense	possibly damaging	0.77
R6190:Ankhd1	UTSW	18	36,611,809 (GRCm38)	missense	possibly damaging	0.84
R6247:Ankhd1	UTSW	18	36,654,146 (GRCm38)	missense	probably benign	0.00
R6512:Ankhd1	UTSW	18	36,591,456 (GRCm38)	missense	probably damaging	1.00
R6649:Ankhd1	UTSW	18	36,600,783 (GRCm38)	splice site	probably null
R6653:Ankhd1	UTSW	18	36,600,783 (GRCm38)	splice site	probably null
R6763:Ankhd1	UTSW	18	36,642,969 (GRCm38)	missense	probably benign	0.31
R6976:Ankhd1	UTSW	18	36,648,254 (GRCm38)	missense	probably benign	0.00
R7075:Ankhd1	UTSW	18	36,559,989 (GRCm38)	missense
R7208:Ankhd1	UTSW	18	36,625,028 (GRCm38)	missense	probably benign
R7305:Ankhd1	UTSW	18	36,632,205 (GRCm38)	missense
R7615:Ankhd1	UTSW	18	36,656,773 (GRCm38)	missense
R7654:Ankhd1	UTSW	18	36,594,101 (GRCm38)	missense	probably damaging	1.00
R7781:Ankhd1	UTSW	18	36,625,205 (GRCm38)	missense	probably damaging	1.00
R7842:Ankhd1	UTSW	18	36,647,828 (GRCm38)	missense	probably benign	0.00
R7965:Ankhd1	UTSW	18	36,658,412 (GRCm38)	missense
R8006:Ankhd1	UTSW	18	36,648,719 (GRCm38)	missense
R8037:Ankhd1	UTSW	18	36,638,623 (GRCm38)	missense	probably damaging	0.98
R8123:Ankhd1	UTSW	18	36,575,083 (GRCm38)	missense
R8195:Ankhd1	UTSW	18	36,654,177 (GRCm38)	missense
R8305:Ankhd1	UTSW	18	36,647,166 (GRCm38)	missense	possibly damaging	0.79
R8708:Ankhd1	UTSW	18	36,594,291 (GRCm38)	missense	probably damaging	1.00
R8827:Ankhd1	UTSW	18	36,624,580 (GRCm38)	nonsense	probably null
R9138:Ankhd1	UTSW	18	36,560,908 (GRCm38)	small deletion	probably benign
R9139:Ankhd1	UTSW	18	36,578,757 (GRCm38)	missense
R9186:Ankhd1	UTSW	18	36,634,330 (GRCm38)	missense	possibly damaging	0.95
R9245:Ankhd1	UTSW	18	36,655,600 (GRCm38)	missense
R9254:Ankhd1	UTSW	18	36,644,627 (GRCm38)	missense	probably benign	0.03
R9262:Ankhd1	UTSW	18	36,632,746 (GRCm38)	missense
R9379:Ankhd1	UTSW	18	36,644,627 (GRCm38)	missense	probably benign	0.03
R9436:Ankhd1	UTSW	18	36,641,601 (GRCm38)	missense	probably benign	0.04
R9436:Ankhd1	UTSW	18	36,560,988 (GRCm38)	missense	probably benign	0.39
R9541:Ankhd1	UTSW	18	36,624,644 (GRCm38)	missense
R9584:Ankhd1	UTSW	18	36,665,451 (GRCm38)	missense	probably benign	0.06
R9664:Ankhd1	UTSW	18	36,647,825 (GRCm38)	missense	probably benign	0.03
RF001:Ankhd1	UTSW	18	36,560,921 (GRCm38)	small insertion	probably benign
RF004:Ankhd1	UTSW	18	36,560,910 (GRCm38)	small insertion	probably benign
RF007:Ankhd1	UTSW	18	36,560,909 (GRCm38)	small insertion	probably benign
RF008:Ankhd1	UTSW	18	36,560,924 (GRCm38)	small insertion	probably benign
RF009:Ankhd1	UTSW	18	36,560,922 (GRCm38)	small insertion	probably benign
RF013:Ankhd1	UTSW	18	36,560,926 (GRCm38)	small insertion	probably benign
RF016:Ankhd1	UTSW	18	36,560,910 (GRCm38)	small insertion	probably benign
RF016:Ankhd1	UTSW	18	36,560,909 (GRCm38)	small insertion	probably benign
RF017:Ankhd1	UTSW	18	36,560,909 (GRCm38)	small insertion	probably benign
RF018:Ankhd1	UTSW	18	36,560,912 (GRCm38)	small insertion	probably benign
RF026:Ankhd1	UTSW	18	36,560,912 (GRCm38)	small insertion	probably benign
RF030:Ankhd1	UTSW	18	36,560,927 (GRCm38)	small insertion	probably benign
RF030:Ankhd1	UTSW	18	36,560,913 (GRCm38)	small insertion	probably benign
RF039:Ankhd1	UTSW	18	36,560,918 (GRCm38)	small insertion	probably benign
RF043:Ankhd1	UTSW	18	36,560,917 (GRCm38)	small insertion	probably benign
RF046:Ankhd1	UTSW	18	36,560,926 (GRCm38)	small insertion	probably benign
RF047:Ankhd1	UTSW	18	36,560,923 (GRCm38)	small insertion	probably benign
RF047:Ankhd1	UTSW	18	36,560,917 (GRCm38)	small insertion	probably benign
RF049:Ankhd1	UTSW	18	36,560,923 (GRCm38)	small insertion	probably benign
RF050:Ankhd1	UTSW	18	36,560,927 (GRCm38)	small insertion	probably benign
RF054:Ankhd1	UTSW	18	36,560,929 (GRCm38)	small insertion	probably benign
RF057:Ankhd1	UTSW	18	36,560,929 (GRCm38)	small insertion	probably benign
RF060:Ankhd1	UTSW	18	36,560,922 (GRCm38)	small insertion	probably benign
RF061:Ankhd1	UTSW	18	36,560,921 (GRCm38)	small insertion	probably benign
RF062:Ankhd1	UTSW	18	36,560,918 (GRCm38)	small insertion	probably benign
X0027:Ankhd1	UTSW	18	36,624,832 (GRCm38)	missense	probably damaging	1.00
X0065:Ankhd1	UTSW	18	36,578,764 (GRCm38)	nonsense	probably null
X0066:Ankhd1	UTSW	18	36,646,704 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GCCTGGCATAACATTTTACAGTATG -3'
(R):5'- GCCTAATGAGACCCTGTTTGG -3'

Sequencing Primer
(F):5'- CATGTTTTCATTGTAAGATTACTGGG -3'
(R):5'- TGACCCCTTTTAGGACTAG -3'

Posted On

2014-08-25