Mutagenetix > Incidental Mutation

Incidental Mutation 'R2046:Dnah10'

221946

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

040053-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2046 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

124725085-124834308 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 124796341 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Asparagine at position 2542 (K2542N)

Ref Sequence

ENSEMBL: ENSMUSP00000062995 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000058440
AA Change: K2542N

PolyPhen 2 Score 0.252 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: K2542N

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000126998

Predicted Effect

probably benign
Transcript: ENSMUST00000141137
AA Change: K2485N

PolyPhen 2 Score 0.117 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: K2485N

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.8%
20x: 94.0%

Validation Efficiency

97% (71/73)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930503L19Rik	T	A	18: 70,467,482 (GRCm38)	D84V	probably damaging	Het
Abcc5	A	T	16: 20,399,817 (GRCm38)	S272T	possibly damaging	Het
Adgre4	A	G	17: 55,778,847 (GRCm38)	N49D	possibly damaging	Het
Ap2b1	A	T	11: 83,336,386 (GRCm38)	Y328F	probably benign	Het
Arhgef33	G	C	17: 80,373,466 (GRCm38)	E678D	probably benign	Het
Arid2	G	A	15: 96,369,387 (GRCm38)	V583I	probably damaging	Het
Bdkrb1	T	A	12: 105,604,726 (GRCm38)	S184T	probably benign	Het
Bend3	T	C	10: 43,511,846 (GRCm38)	F745S	probably damaging	Het
Card10	A	T	15: 78,787,473 (GRCm38)	V597E	possibly damaging	Het
Casp3	T	A	8: 46,629,726 (GRCm38)		probably benign	Het
Ccnb2	A	G	9: 70,409,347 (GRCm38)	V340A	probably benign	Het
Cdkl3	G	T	11: 52,026,850 (GRCm38)	V325L	probably benign	Het
Clec4n	T	A	6: 123,246,504 (GRCm38)	N153K	probably benign	Het
Crtac1	C	T	19: 42,334,053 (GRCm38)	V83I	probably damaging	Het
Cul9	C	A	17: 46,543,733 (GRCm38)	L14F	probably damaging	Het
Dgka	T	C	10: 128,723,535 (GRCm38)	Y519C	probably damaging	Het
Dhrs7	T	G	12: 72,652,266 (GRCm38)	K314T	possibly damaging	Het
Dnaaf9	T	A	2: 130,810,917 (GRCm38)	I42L	possibly damaging	Het
Dock5	A	T	14: 67,812,142 (GRCm38)	V731E	probably benign	Het
Dpy19l1	T	A	9: 24,423,159 (GRCm38)	H571L	probably damaging	Het
Dzip1	A	T	14: 118,922,478 (GRCm38)	I106N	probably damaging	Het
Eif2ak4	A	T	2: 118,451,408 (GRCm38)		probably benign	Het
Epha4	T	C	1: 77,507,162 (GRCm38)	Y70C	probably damaging	Het
Eps15	T	C	4: 109,370,596 (GRCm38)	F344S	probably damaging	Het
Erbb4	C	T	1: 68,298,323 (GRCm38)	R612Q	probably benign	Het
Fam83h	T	C	15: 76,002,938 (GRCm38)	H850R	probably benign	Het
Fancg	A	G	4: 43,004,604 (GRCm38)	C484R	probably damaging	Het
Fzd9	A	G	5: 135,249,684 (GRCm38)	I449T	probably damaging	Het
Gm10647	A	G	9: 66,798,237 (GRCm38)		probably benign	Het
Iigp1c	T	A	18: 60,245,499 (GRCm38)	H35Q	probably benign	Het
Itga11	C	T	9: 62,727,697 (GRCm38)	L86F	probably damaging	Het
Lamc2	C	T	1: 153,141,765 (GRCm38)	R492H	probably benign	Het
Marchf6	A	G	15: 31,486,434 (GRCm38)	V325A	probably benign	Het
Myo5b	A	T	18: 74,577,455 (GRCm38)	I47F	probably benign	Het
Nek9	T	A	12: 85,320,707 (GRCm38)		probably benign	Het
Nelfb	T	A	2: 25,206,311 (GRCm38)	N262I	probably damaging	Het
Neurl4	A	G	11: 69,908,697 (GRCm38)	D942G	probably damaging	Het
Nipbl	G	A	15: 8,324,467 (GRCm38)	P1729S	probably benign	Het
Nr4a3	A	G	4: 48,067,807 (GRCm38)	T468A	possibly damaging	Het
Nrm	G	A	17: 35,864,217 (GRCm38)	V146I	probably benign	Het
Or8h9	C	A	2: 86,958,733 (GRCm38)	A242S	possibly damaging	Het
Pitx3	T	C	19: 46,137,179 (GRCm38)	E42G	possibly damaging	Het
Pkd1l2	C	T	8: 116,999,955 (GRCm38)	A2271T	probably damaging	Het
Pofut2	A	G	10: 77,260,594 (GRCm38)	N51S	probably damaging	Het
Ppp1r3a	T	C	6: 14,722,104 (GRCm38)	E273G	probably benign	Het
Psme4	A	G	11: 30,817,723 (GRCm38)		probably benign	Het
Pus7l	T	C	15: 94,540,785 (GRCm38)	I60V	probably benign	Het
Pygo2	T	A	3: 89,433,148 (GRCm38)	N284K	possibly damaging	Het
Ralgapa1	C	T	12: 55,695,160 (GRCm38)	C1368Y	probably damaging	Het
Rbm45	G	A	2: 76,375,398 (GRCm38)	G198E	probably benign	Het
Reln	T	C	5: 21,942,627 (GRCm38)	I2442V	probably benign	Het
Rmi1	T	C	13: 58,407,958 (GRCm38)	V7A	probably benign	Het
Rsf1	T	C	7: 97,661,677 (GRCm38)	L538P	probably benign	Het
Rsph4a	T	G	10: 33,914,543 (GRCm38)		probably benign	Het
Sardh	A	T	2: 27,215,082 (GRCm38)	D676E	possibly damaging	Het
Sh3tc2	A	G	18: 61,990,843 (GRCm38)	M892V	probably benign	Het
Slc38a11	A	G	2: 65,358,185 (GRCm38)	F80S	probably damaging	Het
Slc6a2	C	A	8: 92,972,926 (GRCm38)	S194*	probably null	Het
Slco2b1	A	G	7: 99,690,479 (GRCm38)	F86L	probably damaging	Het
Smc3	G	A	19: 53,639,414 (GRCm38)	D875N	probably benign	Het
Sp100	G	A	1: 85,709,065 (GRCm38)	E575K	possibly damaging	Het
Spns2	A	G	11: 72,459,040 (GRCm38)	L196P	possibly damaging	Het
Taf8	A	G	17: 47,490,276 (GRCm38)	S261P	probably benign	Het
Trim2	A	G	3: 84,208,289 (GRCm38)	L86P	probably damaging	Het
Ttn	C	A	2: 76,907,794 (GRCm38)	V4134F	probably benign	Het
Ush2a	A	G	1: 188,356,927 (GRCm38)	T360A	probably benign	Het
Usp28	T	A	9: 49,039,075 (GRCm38)	C935S	probably damaging	Het
Vps37d	T	A	5: 135,073,977 (GRCm38)	M134L	probably benign	Het
Vwa2	T	G	19: 56,905,578 (GRCm38)	V329G	probably benign	Het
Zfp110	A	G	7: 12,849,422 (GRCm38)	R666G	probably benign	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,828,603 (GRCm38)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,746,616 (GRCm38)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,794,341 (GRCm38)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,775,512 (GRCm38)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,777,212 (GRCm38)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,779,154 (GRCm38)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,783,946 (GRCm38)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,821,341 (GRCm38)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,732,489 (GRCm38)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,803,328 (GRCm38)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,787,465 (GRCm38)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,768,927 (GRCm38)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,755,786 (GRCm38)	missense	probably benign
IGL01767:Dnah10	APN	5	124,743,737 (GRCm38)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,764,944 (GRCm38)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,783,921 (GRCm38)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,789,812 (GRCm38)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,804,746 (GRCm38)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,819,366 (GRCm38)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,833,423 (GRCm38)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,773,067 (GRCm38)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,773,819 (GRCm38)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,793,852 (GRCm38)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,821,287 (GRCm38)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,787,331 (GRCm38)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,799,005 (GRCm38)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,773,745 (GRCm38)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,826,863 (GRCm38)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,730,086 (GRCm38)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,798,014 (GRCm38)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,801,822 (GRCm38)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,763,133 (GRCm38)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,730,162 (GRCm38)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,764,886 (GRCm38)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,748,457 (GRCm38)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,817,643 (GRCm38)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,817,697 (GRCm38)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,754,290 (GRCm38)	missense	probably benign	0.06
frosty	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,829,529 (GRCm38)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,730,100 (GRCm38)	missense	probably benign
P0019:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
P0037:Dnah10	UTSW	5	124,817,992 (GRCm38)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,775,524 (GRCm38)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,726,902 (GRCm38)	missense	probably benign
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,800,891 (GRCm38)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,830,744 (GRCm38)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,763,076 (GRCm38)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,783,834 (GRCm38)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,834,075 (GRCm38)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,796,369 (GRCm38)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,823,352 (GRCm38)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,755,735 (GRCm38)	missense	probably benign
R0480:Dnah10	UTSW	5	124,808,851 (GRCm38)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,812,723 (GRCm38)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,775,250 (GRCm38)	splice site	probably null
R0599:Dnah10	UTSW	5	124,800,953 (GRCm38)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,747,718 (GRCm38)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,750,812 (GRCm38)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,829,577 (GRCm38)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,797,938 (GRCm38)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,760,014 (GRCm38)	splice site	probably null
R1248:Dnah10	UTSW	5	124,755,823 (GRCm38)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,753,326 (GRCm38)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,774,986 (GRCm38)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,762,221 (GRCm38)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,798,945 (GRCm38)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,789,796 (GRCm38)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,743,686 (GRCm38)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1466:Dnah10	UTSW	5	124,763,096 (GRCm38)	missense	probably benign
R1479:Dnah10	UTSW	5	124,777,889 (GRCm38)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,754,239 (GRCm38)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,760,952 (GRCm38)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,829,614 (GRCm38)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,765,562 (GRCm38)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,760,091 (GRCm38)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,773,190 (GRCm38)	splice site	probably null
R1828:Dnah10	UTSW	5	124,761,279 (GRCm38)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,804,689 (GRCm38)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,832,526 (GRCm38)	splice site	probably null
R1893:Dnah10	UTSW	5	124,754,317 (GRCm38)	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124,758,430 (GRCm38)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,800,984 (GRCm38)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,782,268 (GRCm38)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,775,203 (GRCm38)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,833,988 (GRCm38)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,829,587 (GRCm38)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,746,704 (GRCm38)	missense	probably benign	0.30
R2074:Dnah10	UTSW	5	124,814,674 (GRCm38)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,774,981 (GRCm38)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,761,237 (GRCm38)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,731,466 (GRCm38)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,819,221 (GRCm38)	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124,742,000 (GRCm38)	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124,762,865 (GRCm38)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,775,478 (GRCm38)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,817,670 (GRCm38)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,819,412 (GRCm38)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,796,258 (GRCm38)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,747,630 (GRCm38)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,773,031 (GRCm38)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,777,926 (GRCm38)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,730,137 (GRCm38)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,732,330 (GRCm38)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,819,925 (GRCm38)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,762,869 (GRCm38)	splice site	probably null
R4651:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,729,143 (GRCm38)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,828,472 (GRCm38)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,775,517 (GRCm38)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,747,745 (GRCm38)	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124,819,344 (GRCm38)	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124,773,132 (GRCm38)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,817,748 (GRCm38)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,762,196 (GRCm38)	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124,832,513 (GRCm38)	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,779,258 (GRCm38)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,798,960 (GRCm38)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,787,420 (GRCm38)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,785,156 (GRCm38)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,828,137 (GRCm38)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,791,787 (GRCm38)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,773,566 (GRCm38)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,743,629 (GRCm38)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,830,493 (GRCm38)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,753,168 (GRCm38)	missense	probably benign
R5587:Dnah10	UTSW	5	124,793,913 (GRCm38)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,742,026 (GRCm38)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,821,386 (GRCm38)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,747,746 (GRCm38)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,823,373 (GRCm38)	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124,791,791 (GRCm38)	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124,811,482 (GRCm38)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,808,729 (GRCm38)	missense	probably benign
R6021:Dnah10	UTSW	5	124,736,984 (GRCm38)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,801,860 (GRCm38)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,819,210 (GRCm38)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,805,897 (GRCm38)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,753,174 (GRCm38)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,785,175 (GRCm38)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,770,599 (GRCm38)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,823,318 (GRCm38)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,743,679 (GRCm38)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,794,219 (GRCm38)	splice site	probably null
R6275:Dnah10	UTSW	5	124,785,184 (GRCm38)	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124,775,080 (GRCm38)	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124,829,646 (GRCm38)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,809,269 (GRCm38)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,762,782 (GRCm38)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,758,355 (GRCm38)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,830,033 (GRCm38)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,760,159 (GRCm38)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,805,805 (GRCm38)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,808,812 (GRCm38)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,777,826 (GRCm38)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,790,000 (GRCm38)	splice site	probably null
R6932:Dnah10	UTSW	5	124,821,450 (GRCm38)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,787,426 (GRCm38)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,816,142 (GRCm38)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,822,945 (GRCm38)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,822,942 (GRCm38)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,813,828 (GRCm38)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,791,791 (GRCm38)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,832,598 (GRCm38)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,821,269 (GRCm38)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,747,739 (GRCm38)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,799,031 (GRCm38)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,746,544 (GRCm38)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,817,712 (GRCm38)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,777,234 (GRCm38)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,782,361 (GRCm38)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,726,885 (GRCm38)	missense	probably benign
R7999:Dnah10	UTSW	5	124,725,258 (GRCm38)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,800,885 (GRCm38)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,746,612 (GRCm38)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,828,511 (GRCm38)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,754,266 (GRCm38)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,800,882 (GRCm38)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,755,726 (GRCm38)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,828,460 (GRCm38)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,750,794 (GRCm38)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,782,346 (GRCm38)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,832,502 (GRCm38)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,773,542 (GRCm38)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,736,831 (GRCm38)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,816,100 (GRCm38)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,726,847 (GRCm38)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,814,621 (GRCm38)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,775,346 (GRCm38)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,765,550 (GRCm38)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,818,117 (GRCm38)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,789,764 (GRCm38)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,800,951 (GRCm38)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,813,942 (GRCm38)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,736,993 (GRCm38)	missense
R9001:Dnah10	UTSW	5	124,775,451 (GRCm38)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,743,719 (GRCm38)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,828,077 (GRCm38)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,762,173 (GRCm38)	missense
R9133:Dnah10	UTSW	5	124,782,359 (GRCm38)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,830,411 (GRCm38)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,794,373 (GRCm38)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,741,925 (GRCm38)	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124,736,836 (GRCm38)	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124,768,926 (GRCm38)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,794,443 (GRCm38)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,746,613 (GRCm38)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,823,444 (GRCm38)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,830,043 (GRCm38)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,775,185 (GRCm38)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,818,077 (GRCm38)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,777,907 (GRCm38)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,763,066 (GRCm38)	missense	probably benign
U24488:Dnah10	UTSW	5	124,813,980 (GRCm38)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,765,697 (GRCm38)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,775,355 (GRCm38)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,741,955 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,817,988 (GRCm38)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,747,619 (GRCm38)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- AGTTCCTGTCTGTCCTGTGAAAG -3'
(R):5'- AAGAATCCCAAGTGGCCCATG -3'

Sequencing Primer
(F):5'- CGCAGACAGCTCATTCTAGATGTG -3'
(R):5'- AAGTGGCCCATGGTGCTG -3'

Posted On

2014-08-25