Incidental Mutation 'R0139:Pdcd11'
| ID |
22223 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pdcd11
|
| Ensembl Gene |
ENSMUSG00000025047 |
| Gene Name |
programmed cell death 11 |
| Synonyms |
ALG-4, 1110021I22Rik |
| MMRRC Submission |
038424-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.968)
|
| Stock # |
R0139 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
19 |
| Chromosomal Location |
47079183-47119585 bp(+) (GRCm39) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
A to G
at 47099398 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072008
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072141]
[ENSMUST00000072141]
[ENSMUST00000140512]
|
| AlphaFold |
Q6NS46 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000072141
|
| SMART Domains |
Protein: ENSMUSP00000072008
Gene: ENSMUSG00000025047
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
76 |
N/A |
INTRINSIC |
|
S1
|
81 |
171 |
1.05e-7 |
SMART |
|
S1
|
185 |
258 |
2.32e-9 |
SMART |
|
S1
|
279 |
346 |
1.44e-5 |
SMART |
|
S1
|
363 |
436 |
8.55e-8 |
SMART |
|
S1
|
451 |
522 |
3.89e-20 |
SMART |
|
S1
|
540 |
611 |
1.14e-17 |
SMART |
|
S1
|
634 |
707 |
2.76e-2 |
SMART |
|
S1
|
727 |
798 |
2.02e-18 |
SMART |
|
low complexity region
|
813 |
823 |
N/A |
INTRINSIC |
|
S1
|
844 |
911 |
6.13e0 |
SMART |
|
Blast:S1
|
923 |
993 |
8e-39 |
BLAST |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
S1
|
1045 |
1120 |
1.3e-7 |
SMART |
|
S1
|
1158 |
1233 |
6.09e-4 |
SMART |
|
S1
|
1239 |
1309 |
4.14e-6 |
SMART |
|
S1
|
1333 |
1407 |
1.57e-6 |
SMART |
|
low complexity region
|
1433 |
1473 |
N/A |
INTRINSIC |
|
coiled coil region
|
1557 |
1588 |
N/A |
INTRINSIC |
|
HAT
|
1591 |
1622 |
6.53e2 |
SMART |
|
HAT
|
1624 |
1661 |
4.12e1 |
SMART |
|
HAT
|
1663 |
1694 |
3.49e2 |
SMART |
|
HAT
|
1696 |
1728 |
3.18e-1 |
SMART |
|
HAT
|
1730 |
1764 |
2.25e2 |
SMART |
|
HAT
|
1766 |
1798 |
8.52e-2 |
SMART |
|
HAT
|
1800 |
1835 |
1.33e1 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000072141
|
| SMART Domains |
Protein: ENSMUSP00000072008
Gene: ENSMUSG00000025047
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
76 |
N/A |
INTRINSIC |
|
S1
|
81 |
171 |
1.05e-7 |
SMART |
|
S1
|
185 |
258 |
2.32e-9 |
SMART |
|
S1
|
279 |
346 |
1.44e-5 |
SMART |
|
S1
|
363 |
436 |
8.55e-8 |
SMART |
|
S1
|
451 |
522 |
3.89e-20 |
SMART |
|
S1
|
540 |
611 |
1.14e-17 |
SMART |
|
S1
|
634 |
707 |
2.76e-2 |
SMART |
|
S1
|
727 |
798 |
2.02e-18 |
SMART |
|
low complexity region
|
813 |
823 |
N/A |
INTRINSIC |
|
S1
|
844 |
911 |
6.13e0 |
SMART |
|
Blast:S1
|
923 |
993 |
8e-39 |
BLAST |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
S1
|
1045 |
1120 |
1.3e-7 |
SMART |
|
S1
|
1158 |
1233 |
6.09e-4 |
SMART |
|
S1
|
1239 |
1309 |
4.14e-6 |
SMART |
|
S1
|
1333 |
1407 |
1.57e-6 |
SMART |
|
low complexity region
|
1433 |
1473 |
N/A |
INTRINSIC |
|
coiled coil region
|
1557 |
1588 |
N/A |
INTRINSIC |
|
HAT
|
1591 |
1622 |
6.53e2 |
SMART |
|
HAT
|
1624 |
1661 |
4.12e1 |
SMART |
|
HAT
|
1663 |
1694 |
3.49e2 |
SMART |
|
HAT
|
1696 |
1728 |
3.18e-1 |
SMART |
|
HAT
|
1730 |
1764 |
2.25e2 |
SMART |
|
HAT
|
1766 |
1798 |
8.52e-2 |
SMART |
|
HAT
|
1800 |
1835 |
1.33e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140512
|
| SMART Domains |
Protein: ENSMUSP00000121661
Gene: ENSMUSG00000033033
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Ca_hom_mod
|
6 |
258 |
2.9e-93 |
PFAM |
|
| Meta Mutation Damage Score |
0.9592 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.9%
- 20x: 91.2%
|
| Validation Efficiency |
97% (89/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A230072I06Rik |
C |
T |
8: 12,329,899 (GRCm39) |
S118L |
unknown |
Het |
| Adprs |
A |
G |
4: 126,211,947 (GRCm39) |
Y122H |
probably damaging |
Het |
| Ankrd52 |
T |
C |
10: 128,222,007 (GRCm39) |
S544P |
probably benign |
Het |
| Aopep |
A |
G |
13: 63,338,298 (GRCm39) |
N558S |
probably benign |
Het |
| Arhgef7 |
A |
G |
8: 11,850,503 (GRCm39) |
E111G |
probably damaging |
Het |
| Atp11a |
A |
G |
8: 12,896,054 (GRCm39) |
M755V |
probably benign |
Het |
| Atp2a2 |
A |
G |
5: 122,629,778 (GRCm39) |
I97T |
probably damaging |
Het |
| Bmp3 |
G |
A |
5: 99,027,768 (GRCm39) |
D463N |
possibly damaging |
Het |
| Cacna2d4 |
T |
C |
6: 119,255,230 (GRCm39) |
|
probably benign |
Het |
| Ccdc28a |
G |
A |
10: 18,106,188 (GRCm39) |
S46F |
possibly damaging |
Het |
| Ccdc40 |
G |
A |
11: 119,155,125 (GRCm39) |
G1122S |
probably benign |
Het |
| Cenpw |
T |
G |
10: 30,076,455 (GRCm39) |
T8P |
probably benign |
Het |
| Cfap44 |
G |
C |
16: 44,253,785 (GRCm39) |
G893R |
possibly damaging |
Het |
| Cimap3 |
A |
T |
3: 105,906,886 (GRCm39) |
M171K |
possibly damaging |
Het |
| Cops7a |
A |
T |
6: 124,938,323 (GRCm39) |
C110S |
probably damaging |
Het |
| Cstl1 |
A |
G |
2: 148,597,245 (GRCm39) |
N134S |
probably damaging |
Het |
| Cyp2s1 |
G |
T |
7: 25,511,114 (GRCm39) |
|
probably null |
Het |
| Dio2 |
T |
A |
12: 90,696,617 (GRCm39) |
N124Y |
probably damaging |
Het |
| Ecel1 |
C |
A |
1: 87,082,248 (GRCm39) |
G155V |
possibly damaging |
Het |
| Efr3a |
G |
T |
15: 65,717,830 (GRCm39) |
V337F |
possibly damaging |
Het |
| Eva1b |
A |
C |
4: 126,043,446 (GRCm39) |
H162P |
probably damaging |
Het |
| Exoc5 |
C |
T |
14: 49,273,493 (GRCm39) |
E301K |
probably damaging |
Het |
| F13b |
G |
A |
1: 139,435,941 (GRCm39) |
S249N |
probably damaging |
Het |
| Fam120b |
C |
T |
17: 15,646,446 (GRCm39) |
|
probably benign |
Het |
| Gbf1 |
T |
C |
19: 46,250,231 (GRCm39) |
L396S |
probably damaging |
Het |
| Gck |
T |
A |
11: 5,859,139 (GRCm39) |
K143* |
probably null |
Het |
| Gck |
C |
A |
11: 5,860,370 (GRCm39) |
V91L |
probably damaging |
Het |
| Glt8d2 |
T |
C |
10: 82,496,644 (GRCm39) |
N138S |
probably damaging |
Het |
| Gm4884 |
T |
C |
7: 40,692,387 (GRCm39) |
F119L |
probably benign |
Het |
| Igsf11 |
T |
C |
16: 38,829,240 (GRCm39) |
S45P |
probably damaging |
Het |
| Iho1 |
T |
C |
9: 108,289,695 (GRCm39) |
T176A |
probably damaging |
Het |
| Il10 |
G |
A |
1: 130,950,271 (GRCm39) |
V142M |
probably damaging |
Het |
| Insc |
A |
T |
7: 114,368,237 (GRCm39) |
H9L |
probably damaging |
Het |
| Iqsec1 |
G |
T |
6: 90,786,740 (GRCm39) |
|
probably benign |
Het |
| Katnb1 |
A |
G |
8: 95,825,050 (GRCm39) |
S611G |
possibly damaging |
Het |
| Kcnb1 |
A |
G |
2: 166,947,459 (GRCm39) |
I463T |
possibly damaging |
Het |
| Lao1 |
A |
G |
4: 118,821,399 (GRCm39) |
N90S |
probably benign |
Het |
| Med16 |
T |
A |
10: 79,732,635 (GRCm39) |
M710L |
probably benign |
Het |
| Mroh2a |
G |
C |
1: 88,185,524 (GRCm39) |
E1510D |
probably damaging |
Het |
| Mtus1 |
G |
A |
8: 41,469,233 (GRCm39) |
|
probably benign |
Het |
| Mybpc3 |
A |
G |
2: 90,950,682 (GRCm39) |
|
probably benign |
Het |
| Ndor1 |
C |
T |
2: 25,138,366 (GRCm39) |
V405M |
possibly damaging |
Het |
| Nell2 |
A |
G |
15: 95,330,782 (GRCm39) |
V213A |
probably benign |
Het |
| Nme8 |
T |
C |
13: 19,862,018 (GRCm39) |
I204V |
probably benign |
Het |
| Nup133 |
A |
T |
8: 124,656,082 (GRCm39) |
N466K |
probably benign |
Het |
| Nxt1 |
A |
G |
2: 148,517,390 (GRCm39) |
T44A |
probably benign |
Het |
| Or14c46 |
T |
C |
7: 85,918,187 (GRCm39) |
E270G |
probably benign |
Het |
| Or2ag15 |
A |
T |
7: 106,340,832 (GRCm39) |
I103N |
probably benign |
Het |
| Or2y12 |
C |
T |
11: 49,426,401 (GRCm39) |
L130F |
probably benign |
Het |
| Or4e1 |
T |
C |
14: 52,700,669 (GRCm39) |
T239A |
probably damaging |
Het |
| Or4f7 |
A |
T |
2: 111,644,699 (GRCm39) |
I124K |
possibly damaging |
Het |
| Or7e168 |
C |
T |
9: 19,720,165 (GRCm39) |
L184F |
probably damaging |
Het |
| Pced1a |
T |
C |
2: 130,263,827 (GRCm39) |
K275R |
probably benign |
Het |
| Phldb2 |
A |
C |
16: 45,591,029 (GRCm39) |
|
probably benign |
Het |
| Piwil1 |
C |
A |
5: 128,824,387 (GRCm39) |
S490Y |
probably damaging |
Het |
| Plekhh3 |
T |
C |
11: 101,054,501 (GRCm39) |
|
probably benign |
Het |
| Ppargc1b |
A |
T |
18: 61,449,034 (GRCm39) |
|
probably benign |
Het |
| Psg19 |
C |
T |
7: 18,530,942 (GRCm39) |
V71I |
possibly damaging |
Het |
| Ptk6 |
T |
C |
2: 180,838,724 (GRCm39) |
|
probably benign |
Het |
| Pus7 |
A |
G |
5: 23,983,090 (GRCm39) |
S126P |
probably damaging |
Het |
| Rab6b |
T |
A |
9: 103,017,576 (GRCm39) |
|
probably null |
Het |
| Ranbp3 |
G |
A |
17: 57,016,272 (GRCm39) |
R347Q |
possibly damaging |
Het |
| Sanbr |
A |
T |
11: 23,570,214 (GRCm39) |
|
probably benign |
Het |
| Sbf1 |
A |
T |
15: 89,186,701 (GRCm39) |
L866Q |
probably damaging |
Het |
| Slc25a34 |
A |
G |
4: 141,349,663 (GRCm39) |
V164A |
possibly damaging |
Het |
| Smg1 |
A |
G |
7: 117,751,898 (GRCm39) |
|
probably null |
Het |
| Spin1 |
G |
T |
13: 51,303,048 (GRCm39) |
V214L |
probably benign |
Het |
| Spmip2 |
A |
T |
3: 79,313,142 (GRCm39) |
Y72F |
probably damaging |
Het |
| Sptbn1 |
T |
C |
11: 30,092,289 (GRCm39) |
N492S |
probably benign |
Het |
| Stk-ps2 |
A |
G |
1: 46,068,955 (GRCm39) |
|
noncoding transcript |
Het |
| Taar7f |
T |
C |
10: 23,926,312 (GRCm39) |
I302T |
probably benign |
Het |
| Tdrd1 |
C |
A |
19: 56,831,630 (GRCm39) |
H340Q |
probably benign |
Het |
| Thumpd3 |
A |
G |
6: 113,044,762 (GRCm39) |
D498G |
probably benign |
Het |
| Tpgs2 |
A |
G |
18: 25,282,242 (GRCm39) |
L103P |
probably damaging |
Het |
| Trip10 |
A |
G |
17: 57,568,633 (GRCm39) |
|
probably null |
Het |
| Trip6 |
A |
T |
5: 137,310,436 (GRCm39) |
H269Q |
probably benign |
Het |
| Trmt12 |
T |
C |
15: 58,744,743 (GRCm39) |
V47A |
possibly damaging |
Het |
| Trpm7 |
A |
T |
2: 126,654,691 (GRCm39) |
S1416T |
probably benign |
Het |
| Tsks |
G |
A |
7: 44,603,883 (GRCm39) |
A438T |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,727,630 (GRCm39) |
|
probably benign |
Het |
| Twf2 |
G |
A |
9: 106,090,155 (GRCm39) |
V136M |
possibly damaging |
Het |
| Uty |
A |
C |
Y: 1,197,223 (GRCm39) |
Y115D |
probably damaging |
Het |
| Vcan |
A |
G |
13: 89,839,380 (GRCm39) |
S2055P |
probably damaging |
Het |
| Yes1 |
A |
G |
5: 32,842,039 (GRCm39) |
Q521R |
possibly damaging |
Het |
| Zfp114 |
A |
T |
7: 23,880,685 (GRCm39) |
T344S |
possibly damaging |
Het |
| Zfp661 |
A |
T |
2: 127,420,532 (GRCm39) |
V89D |
possibly damaging |
Het |
| Zfp91 |
A |
T |
19: 12,747,834 (GRCm39) |
Y430N |
probably damaging |
Het |
|
| Other mutations in Pdcd11 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00646:Pdcd11
|
APN |
19 |
47,105,767 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL00656:Pdcd11
|
APN |
19 |
47,086,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00754:Pdcd11
|
APN |
19 |
47,092,221 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL00907:Pdcd11
|
APN |
19 |
47,096,003 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL00987:Pdcd11
|
APN |
19 |
47,102,989 (GRCm39) |
intron |
probably benign |
|
|
IGL01346:Pdcd11
|
APN |
19 |
47,098,053 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01529:Pdcd11
|
APN |
19 |
47,098,068 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01670:Pdcd11
|
APN |
19 |
47,094,743 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01917:Pdcd11
|
APN |
19 |
47,089,604 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02096:Pdcd11
|
APN |
19 |
47,094,860 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02300:Pdcd11
|
APN |
19 |
47,115,381 (GRCm39) |
missense |
probably benign |
|
|
IGL02515:Pdcd11
|
APN |
19 |
47,113,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02886:Pdcd11
|
APN |
19 |
47,102,064 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03158:Pdcd11
|
APN |
19 |
47,116,500 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0100:Pdcd11
|
UTSW |
19 |
47,091,105 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0100:Pdcd11
|
UTSW |
19 |
47,091,105 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0128:Pdcd11
|
UTSW |
19 |
47,108,301 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0227:Pdcd11
|
UTSW |
19 |
47,101,876 (GRCm39) |
intron |
probably benign |
|
|
R0316:Pdcd11
|
UTSW |
19 |
47,101,611 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0480:Pdcd11
|
UTSW |
19 |
47,113,476 (GRCm39) |
intron |
probably benign |
|
|
R0577:Pdcd11
|
UTSW |
19 |
47,087,271 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0725:Pdcd11
|
UTSW |
19 |
47,115,730 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1344:Pdcd11
|
UTSW |
19 |
47,118,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1418:Pdcd11
|
UTSW |
19 |
47,118,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Pdcd11
|
UTSW |
19 |
47,086,626 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2146:Pdcd11
|
UTSW |
19 |
47,093,191 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2147:Pdcd11
|
UTSW |
19 |
47,093,191 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2447:Pdcd11
|
UTSW |
19 |
47,102,995 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2916:Pdcd11
|
UTSW |
19 |
47,101,876 (GRCm39) |
intron |
probably benign |
|
|
R3177:Pdcd11
|
UTSW |
19 |
47,101,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3277:Pdcd11
|
UTSW |
19 |
47,101,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Pdcd11
|
UTSW |
19 |
47,115,684 (GRCm39) |
intron |
probably benign |
|
|
R4495:Pdcd11
|
UTSW |
19 |
47,099,445 (GRCm39) |
missense |
probably benign |
|
|
R4697:Pdcd11
|
UTSW |
19 |
47,114,786 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4941:Pdcd11
|
UTSW |
19 |
47,108,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4953:Pdcd11
|
UTSW |
19 |
47,116,404 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5048:Pdcd11
|
UTSW |
19 |
47,095,554 (GRCm39) |
missense |
probably benign |
|
|
R5049:Pdcd11
|
UTSW |
19 |
47,095,554 (GRCm39) |
missense |
probably benign |
|
|
R5103:Pdcd11
|
UTSW |
19 |
47,112,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5107:Pdcd11
|
UTSW |
19 |
47,094,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5139:Pdcd11
|
UTSW |
19 |
47,095,554 (GRCm39) |
missense |
probably benign |
|
|
R5261:Pdcd11
|
UTSW |
19 |
47,101,976 (GRCm39) |
missense |
probably benign |
|
|
R5302:Pdcd11
|
UTSW |
19 |
47,096,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5592:Pdcd11
|
UTSW |
19 |
47,091,164 (GRCm39) |
missense |
probably benign |
|
|
R5769:Pdcd11
|
UTSW |
19 |
47,091,076 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5791:Pdcd11
|
UTSW |
19 |
47,099,430 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5809:Pdcd11
|
UTSW |
19 |
47,082,247 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5899:Pdcd11
|
UTSW |
19 |
47,093,198 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5901:Pdcd11
|
UTSW |
19 |
47,116,771 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5947:Pdcd11
|
UTSW |
19 |
47,117,702 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6177:Pdcd11
|
UTSW |
19 |
47,108,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6489:Pdcd11
|
UTSW |
19 |
47,098,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6575:Pdcd11
|
UTSW |
19 |
47,098,117 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6578:Pdcd11
|
UTSW |
19 |
47,099,520 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7009:Pdcd11
|
UTSW |
19 |
47,101,581 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7015:Pdcd11
|
UTSW |
19 |
47,086,665 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7060:Pdcd11
|
UTSW |
19 |
47,099,418 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7260:Pdcd11
|
UTSW |
19 |
47,117,673 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7392:Pdcd11
|
UTSW |
19 |
47,116,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7601:Pdcd11
|
UTSW |
19 |
47,094,808 (GRCm39) |
missense |
not run |
|
|
R7759:Pdcd11
|
UTSW |
19 |
47,101,637 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7760:Pdcd11
|
UTSW |
19 |
47,101,637 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7785:Pdcd11
|
UTSW |
19 |
47,093,125 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7793:Pdcd11
|
UTSW |
19 |
47,094,871 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7810:Pdcd11
|
UTSW |
19 |
47,086,659 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7863:Pdcd11
|
UTSW |
19 |
47,085,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Pdcd11
|
UTSW |
19 |
47,101,876 (GRCm39) |
intron |
probably benign |
|
|
R8062:Pdcd11
|
UTSW |
19 |
47,119,152 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8184:Pdcd11
|
UTSW |
19 |
47,101,791 (GRCm39) |
nonsense |
probably null |
|
|
R8278:Pdcd11
|
UTSW |
19 |
47,094,736 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8404:Pdcd11
|
UTSW |
19 |
47,093,231 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8508:Pdcd11
|
UTSW |
19 |
47,108,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8525:Pdcd11
|
UTSW |
19 |
47,081,337 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8787:Pdcd11
|
UTSW |
19 |
47,097,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9019:Pdcd11
|
UTSW |
19 |
47,101,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9534:Pdcd11
|
UTSW |
19 |
47,108,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Pdcd11
|
UTSW |
19 |
47,082,191 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9712:Pdcd11
|
UTSW |
19 |
47,117,741 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF010:Pdcd11
|
UTSW |
19 |
47,101,890 (GRCm39) |
frame shift |
probably null |
|
|
RF027:Pdcd11
|
UTSW |
19 |
47,101,888 (GRCm39) |
frame shift |
probably null |
|
|
RF039:Pdcd11
|
UTSW |
19 |
47,101,894 (GRCm39) |
frame shift |
probably null |
|
|
RF061:Pdcd11
|
UTSW |
19 |
47,101,884 (GRCm39) |
frame shift |
probably null |
|
|
X0065:Pdcd11
|
UTSW |
19 |
47,085,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGACTCAGTACATGAACCACCACG -3'
(R):5'- GCCTCAAATGAACCGACTCATCTGC -3'
Sequencing Primer
(F):5'- TGAACCACCACGCCTGG -3'
(R):5'- TTGGAAATTCTGTATCCAGCAGAGG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation