Mutagenetix > Incidental Mutation

Incidental Mutation 'R1981:Igf2r'

222397

Institutional Source

Beutler Lab

Gene Symbol

Igf2r

Ensembl Gene

ENSMUSG00000023830

Gene Name

insulin-like growth factor 2 receptor

Synonyms

M6P/IGF2R, IGF-II/CI-MPR, Mpr300, CI-MPR, CD222, mannose-6-phosphate receptor, cation independent

MMRRC Submission

039993-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.919) question?

Stock #

R1981 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

12682406-12769664 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to A at 12733903 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Stop codon at position 219 (Q219*)

Ref Sequence

ENSEMBL: ENSMUSP00000024599 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000024599]

AlphaFold

Q07113

Predicted Effect

probably null
Transcript: ENSMUST00000024599
AA Change: Q219*

SMART Domains

Protein: ENSMUSP00000024599
Gene: ENSMUSG00000023830
AA Change: Q219*

Domain	Start	End	E-Value	Type
signal peptide	1	35	N/A	INTRINSIC
low complexity region	94	104	N/A	INTRINSIC
Pfam:CIMR	118	266	5.1e-21	PFAM
Pfam:CIMR	272	416	8.8e-22	PFAM
Pfam:CIMR	418	567	3.4e-53	PFAM
Pfam:CIMR	569	709	6.5e-47	PFAM
Pfam:CIMR	713	869	6.5e-34	PFAM
Pfam:CIMR	876	1020	1.9e-10	PFAM
Pfam:CIMR	1024	1171	1e-60	PFAM
Pfam:CIMR	1172	1313	1.2e-17	PFAM
Pfam:CIMR	1315	1455	2.1e-58	PFAM
Pfam:CIMR	1458	1592	1.8e-22	PFAM
Pfam:CIMR	1596	1743	9.1e-23	PFAM
Pfam:CIMR	1748	1887	2.5e-22	PFAM
FN2	1889	1935	9.51e-26	SMART
Pfam:CIMR	1939	2076	2.1e-22	PFAM
Pfam:CIMR	2230	2294	4.9e-9	PFAM
transmembrane domain	2295	2317	N/A	INTRINSIC
low complexity region	2336	2363	N/A	INTRINSIC

Meta Mutation Damage Score

0.9712

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.6%

Validation Efficiency

99% (80/81)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
PHENOTYPE: Mutants inheriting maternally a targeted disruption of this gene exhibit elevated serum and tissue IGF-II levels, overgrowth, organomegaly, kinky tail, polydactyly, heart defects, edema, dyspnea, imperforate vagina, reduced fertility and perinatal death.Survival is influenced by genetic background. [provided by MGI curators]

Allele List at MGI

All alleles(13) : Targeted, knock-out(4) Targeted, other(3) Gene trapped(6)

Other mutations in this stock

Total: 80 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Anks1	T	C	17: 27,985,121 (GRCm38)	V181A	probably damaging	Het
Aqp4	T	C	18: 15,393,551 (GRCm38)	D291G	probably damaging	Het
Atad1	G	T	19: 32,695,810 (GRCm38)	D224E	probably benign	Het
Atp1a3	T	G	7: 25,000,975 (GRCm38)	E33A	probably benign	Het
Baz2b	A	G	2: 59,923,680 (GRCm38)	F1100L	possibly damaging	Het
Car7	C	T	8: 104,548,377 (GRCm38)		probably benign	Het
Casp8	C	A	1: 58,828,962 (GRCm38)		probably null	Het
Cdh23	A	T	10: 60,378,751 (GRCm38)	L1495H	probably damaging	Het
Ceacam9	T	G	7: 16,725,307 (GRCm38)	L177R	probably benign	Het
Col16a1	C	G	4: 130,065,443 (GRCm38)	P346A	unknown	Het
Cyp2c29	A	G	19: 39,307,772 (GRCm38)		probably null	Het
Cyp3a13	T	C	5: 137,911,856 (GRCm38)	S139G	probably damaging	Het
Dapk2	A	G	9: 66,268,898 (GRCm38)	H327R	probably benign	Het
Ddx19b	T	C	8: 111,009,343 (GRCm38)	T357A	possibly damaging	Het
Dnah2	A	G	11: 69,474,325 (GRCm38)	Y1944H	probably damaging	Het
Dnai2	T	A	11: 114,732,929 (GRCm38)	V6E	probably damaging	Het
Eipr1	T	C	12: 28,863,025 (GRCm38)	Y242H	probably damaging	Het
Fam149a	T	G	8: 45,381,741 (GRCm38)	D7A	probably damaging	Het
Fam217a	T	A	13: 34,916,754 (GRCm38)	D140V	probably benign	Het
Fat4	G	A	3: 38,991,664 (GRCm38)	C3944Y	probably damaging	Het
Fezf2	G	T	14: 12,344,405 (GRCm38)	P261T	probably benign	Het
Gcsam	A	T	16: 45,619,974 (GRCm38)	T127S	probably damaging	Het
Git2	C	T	5: 114,749,559 (GRCm38)		probably benign	Het
Gm1527	T	C	3: 28,915,835 (GRCm38)		probably null	Het
Gm7030	T	A	17: 36,128,722 (GRCm38)	D122V	probably damaging	Het
Gtf3c1	A	G	7: 125,644,272 (GRCm38)	L1720P	possibly damaging	Het
Hat1	A	G	2: 71,389,977 (GRCm38)	T28A	probably benign	Het
Impdh1	T	A	6: 29,206,451 (GRCm38)	D129V	possibly damaging	Het
Kcnh8	GAGACCAACGAGCAGCTGATGCTTCAGA	GAGA	17: 52,725,906 (GRCm38)	74	probably benign	Het
Ltbp3	A	G	19: 5,758,079 (GRCm38)	Q1250R	probably benign	Het
Mansc4	T	A	6: 147,075,675 (GRCm38)	I148F	probably benign	Het
Mast2	T	C	4: 116,314,840 (GRCm38)	Y569C	probably damaging	Het
Mcoln3	A	T	3: 146,140,590 (GRCm38)	K552*	probably null	Het
Mctp2	T	C	7: 72,164,698 (GRCm38)	Q601R	probably benign	Het
Mei1	A	G	15: 82,103,312 (GRCm38)	N859S	probably benign	Het
Myo19	A	T	11: 84,892,170 (GRCm38)	Q170L	possibly damaging	Het
Myo1h	T	C	5: 114,353,837 (GRCm38)	F676S	probably damaging	Het
Myo9a	A	G	9: 59,894,146 (GRCm38)	T1876A	probably benign	Het
Nav3	G	T	10: 109,719,090 (GRCm38)		probably benign	Het
Ndor1	T	C	2: 25,255,224 (GRCm38)	Y43C	probably damaging	Het
Nlrp1a	A	G	11: 71,098,938 (GRCm38)	V1102A	probably damaging	Het
Nmnat3	T	C	9: 98,410,299 (GRCm38)	I199T	possibly damaging	Het
Nsun7	T	C	5: 66,261,214 (GRCm38)	S96P	probably damaging	Het
Ntng1	A	G	3: 109,935,010 (GRCm38)	V149A	possibly damaging	Het
Oas3	T	C	5: 120,761,835 (GRCm38)		probably benign	Het
Or10v9	T	G	19: 11,855,007 (GRCm38)	Q315H	possibly damaging	Het
Or4k47	T	A	2: 111,621,241 (GRCm38)	I278F	probably benign	Het
Or5bw2	A	G	7: 6,570,558 (GRCm38)	D189G	probably benign	Het
Or6z7	T	C	7: 6,480,932 (GRCm38)	M75V	probably benign	Het
Or8b3	T	C	9: 38,403,735 (GRCm38)	L287P	probably damaging	Het
Or8k53	A	T	2: 86,347,142 (GRCm38)	I208N	possibly damaging	Het
Pax2	G	A	19: 44,818,465 (GRCm38)	D301N	probably damaging	Het
Pcsk4	T	A	10: 80,325,779 (GRCm38)	E176V	probably damaging	Het
Pkhd1	G	A	1: 20,117,060 (GRCm38)	P3675S	probably benign	Het
Plekho2	A	T	9: 65,558,692 (GRCm38)	L138Q	probably damaging	Het
Ppp4r3c1	A	T	X: 89,931,445 (GRCm38)	V382E	probably damaging	Het
Prkcsh	A	G	9: 22,012,868 (GRCm38)	D458G	probably damaging	Het
Prr11	T	A	11: 87,103,290 (GRCm38)	D100V	probably damaging	Het
Qars1	A	G	9: 108,515,028 (GRCm38)	N136D	probably damaging	Het
Rbm15b	A	G	9: 106,881,623 (GRCm38)		probably benign	Het
Rel	C	T	11: 23,742,761 (GRCm38)	G424D	probably benign	Het
Rsrc1	A	G	3: 67,350,005 (GRCm38)	D250G	probably benign	Het
Samt3	A	C	X: 86,047,134 (GRCm38)	M211L	probably benign	Het
Scn2a	C	A	2: 65,690,170 (GRCm38)	N503K	probably damaging	Het
Sh2d6	G	A	6: 72,517,544 (GRCm38)		probably benign	Het
Smg8	T	C	11: 87,085,331 (GRCm38)	T475A	probably benign	Het
Ssxb10	A	G	X: 8,331,019 (GRCm38)	D77G	probably benign	Het
Tbx20	T	A	9: 24,770,913 (GRCm38)	K48N	possibly damaging	Het
Tead1	C	A	7: 112,891,745 (GRCm38)	D231E	probably benign	Het
Ticam1	C	T	17: 56,271,555 (GRCm38)	R180H	probably damaging	Het
Tjp1	A	T	7: 65,312,855 (GRCm38)	F1111L	probably damaging	Het
Tlr11	T	A	14: 50,361,988 (GRCm38)	I477K	possibly damaging	Het
Ttc13	A	G	8: 124,714,187 (GRCm38)		probably null	Het
Ttc17	T	C	2: 94,326,704 (GRCm38)	N411S	probably benign	Het
Usp15	T	A	10: 123,125,041 (GRCm38)		probably benign	Het
Usp18	A	G	6: 121,252,517 (GRCm38)	K32E	probably benign	Het
Vmn1r12	A	T	6: 57,159,661 (GRCm38)	M248L	probably benign	Het
Zbtb14	C	A	17: 69,388,502 (GRCm38)	F398L	probably damaging	Het
Zfp930	T	A	8: 69,228,172 (GRCm38)	L172H	probably damaging	Het
Zfp976	G	A	7: 42,613,622 (GRCm38)	H264Y	probably damaging	Het

Other mutations in Igf2r

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Igf2r	APN	17	12,713,990 (GRCm38)	missense	probably benign	0.01
IGL00534:Igf2r	APN	17	12,739,328 (GRCm38)	missense	probably damaging	0.97
IGL00902:Igf2r	APN	17	12,700,358 (GRCm38)	missense	probably damaging	0.99
IGL00903:Igf2r	APN	17	12,683,867 (GRCm38)	missense	possibly damaging	0.70
IGL01160:Igf2r	APN	17	12,704,775 (GRCm38)	missense	possibly damaging	0.73
IGL01380:Igf2r	APN	17	12,695,374 (GRCm38)	missense	probably benign	0.01
IGL01392:Igf2r	APN	17	12,704,349 (GRCm38)	missense	probably benign
IGL01557:Igf2r	APN	17	12,704,635 (GRCm38)	missense	possibly damaging	0.82
IGL01568:Igf2r	APN	17	12,683,985 (GRCm38)	missense	possibly damaging	0.93
IGL01611:Igf2r	APN	17	12,725,415 (GRCm38)	nonsense	probably null
IGL01720:Igf2r	APN	17	12,701,313 (GRCm38)	missense	probably damaging	0.99
IGL01756:Igf2r	APN	17	12,683,822 (GRCm38)	missense	probably benign
IGL01839:Igf2r	APN	17	12,705,022 (GRCm38)	missense	probably damaging	1.00
IGL01904:Igf2r	APN	17	12,714,911 (GRCm38)	missense	probably damaging	0.99
IGL01965:Igf2r	APN	17	12,704,338 (GRCm38)	missense	probably benign	0.12
IGL02083:Igf2r	APN	17	12,693,192 (GRCm38)	nonsense	probably null
IGL02095:Igf2r	APN	17	12,702,005 (GRCm38)	missense	probably damaging	0.99
IGL02183:Igf2r	APN	17	12,698,516 (GRCm38)	unclassified	probably benign
IGL02576:Igf2r	APN	17	12,748,763 (GRCm38)	missense	possibly damaging	0.90
IGL02649:Igf2r	APN	17	12,712,087 (GRCm38)	missense	possibly damaging	0.93
IGL02807:Igf2r	APN	17	12,719,883 (GRCm38)	missense	probably damaging	0.98
IGL02833:Igf2r	APN	17	12,692,723 (GRCm38)	missense	probably damaging	0.97
IGL02885:Igf2r	APN	17	12,694,120 (GRCm38)	missense	possibly damaging	0.94
IGL02990:Igf2r	APN	17	12,710,746 (GRCm38)	splice site	probably benign
IGL03080:Igf2r	APN	17	12,726,676 (GRCm38)	missense	probably benign	0.06
IGL03176:Igf2r	APN	17	12,716,672 (GRCm38)	missense	probably damaging	1.00
blunt	UTSW	17	12,722,175 (GRCm38)	missense	probably benign	0.02
brusque	UTSW	17	12,714,951 (GRCm38)	missense	probably damaging	0.98
gruff	UTSW	17	12,684,097 (GRCm38)	missense	probably damaging	0.96
outlier	UTSW	17	12,695,314 (GRCm38)	missense	probably benign	0.20
NA:Igf2r	UTSW	17	12,691,962 (GRCm38)	missense	probably benign
R0165:Igf2r	UTSW	17	12,698,527 (GRCm38)	missense	probably benign	0.07
R0412:Igf2r	UTSW	17	12,683,948 (GRCm38)	missense	probably damaging	0.98
R0523:Igf2r	UTSW	17	12,692,064 (GRCm38)	missense	probably benign	0.27
R0631:Igf2r	UTSW	17	12,717,274 (GRCm38)	splice site	probably null
R0722:Igf2r	UTSW	17	12,715,495 (GRCm38)	critical splice acceptor site	probably null
R0894:Igf2r	UTSW	17	12,692,101 (GRCm38)	missense	probably benign	0.02
R1265:Igf2r	UTSW	17	12,694,124 (GRCm38)	missense	probably damaging	0.98
R1466:Igf2r	UTSW	17	12,717,269 (GRCm38)	splice site	probably benign
R1485:Igf2r	UTSW	17	12,691,285 (GRCm38)	missense	probably damaging	1.00
R1633:Igf2r	UTSW	17	12,726,309 (GRCm38)	missense	probably benign
R1693:Igf2r	UTSW	17	12,704,316 (GRCm38)	missense	probably damaging	0.97
R1751:Igf2r	UTSW	17	12,697,441 (GRCm38)	missense	possibly damaging	0.94
R1843:Igf2r	UTSW	17	12,704,270 (GRCm38)	critical splice donor site	probably null
R1994:Igf2r	UTSW	17	12,692,738 (GRCm38)	missense	probably benign
R2060:Igf2r	UTSW	17	12,701,319 (GRCm38)	missense	possibly damaging	0.92
R2108:Igf2r	UTSW	17	12,698,251 (GRCm38)	missense	probably benign	0.02
R2132:Igf2r	UTSW	17	12,722,208 (GRCm38)	missense	probably benign	0.12
R2314:Igf2r	UTSW	17	12,715,943 (GRCm38)	missense	probably benign	0.28
R2349:Igf2r	UTSW	17	12,722,311 (GRCm38)	splice site	probably null
R2696:Igf2r	UTSW	17	12,695,344 (GRCm38)	missense	possibly damaging	0.96
R2864:Igf2r	UTSW	17	12,686,724 (GRCm38)	missense	probably damaging	0.99
R2865:Igf2r	UTSW	17	12,686,724 (GRCm38)	missense	probably damaging	0.99
R3884:Igf2r	UTSW	17	12,709,468 (GRCm38)	missense	probably benign
R3930:Igf2r	UTSW	17	12,705,829 (GRCm38)	missense	probably benign	0.01
R4021:Igf2r	UTSW	17	12,748,751 (GRCm38)	missense	probably damaging	0.97
R4125:Igf2r	UTSW	17	12,702,254 (GRCm38)	missense	possibly damaging	0.93
R4342:Igf2r	UTSW	17	12,709,511 (GRCm38)	missense	possibly damaging	0.95
R4343:Igf2r	UTSW	17	12,709,511 (GRCm38)	missense	possibly damaging	0.95
R4345:Igf2r	UTSW	17	12,709,511 (GRCm38)	missense	possibly damaging	0.95
R4760:Igf2r	UTSW	17	12,703,465 (GRCm38)	missense	possibly damaging	0.92
R4796:Igf2r	UTSW	17	12,684,126 (GRCm38)	missense	possibly damaging	0.70
R4816:Igf2r	UTSW	17	12,684,097 (GRCm38)	missense	probably damaging	0.96
R4826:Igf2r	UTSW	17	12,701,353 (GRCm38)	missense	probably damaging	0.98
R4933:Igf2r	UTSW	17	12,691,877 (GRCm38)	splice site	probably null
R4980:Igf2r	UTSW	17	12,703,360 (GRCm38)	critical splice donor site	probably null
R5389:Igf2r	UTSW	17	12,725,416 (GRCm38)	missense	probably damaging	1.00
R5473:Igf2r	UTSW	17	12,695,314 (GRCm38)	missense	probably benign	0.20
R5494:Igf2r	UTSW	17	12,693,145 (GRCm38)	missense	possibly damaging	0.74
R5619:Igf2r	UTSW	17	12,739,334 (GRCm38)	missense	probably damaging	1.00
R5738:Igf2r	UTSW	17	12,717,367 (GRCm38)	missense	probably benign	0.23
R5761:Igf2r	UTSW	17	12,698,352 (GRCm38)	splice site	probably null
R5794:Igf2r	UTSW	17	12,709,445 (GRCm38)	missense	probably benign	0.37
R6210:Igf2r	UTSW	17	12,714,951 (GRCm38)	missense	probably damaging	0.98
R6319:Igf2r	UTSW	17	12,714,113 (GRCm38)	missense	probably damaging	1.00
R6388:Igf2r	UTSW	17	12,683,900 (GRCm38)	missense	probably benign
R6396:Igf2r	UTSW	17	12,714,090 (GRCm38)	missense	probably benign	0.00
R6584:Igf2r	UTSW	17	12,701,250 (GRCm38)	missense	probably damaging	0.99
R6590:Igf2r	UTSW	17	12,691,937 (GRCm38)	nonsense	probably null
R6591:Igf2r	UTSW	17	12,689,008 (GRCm38)	missense	probably damaging	1.00
R6599:Igf2r	UTSW	17	12,698,618 (GRCm38)	missense	possibly damaging	0.85
R6690:Igf2r	UTSW	17	12,691,937 (GRCm38)	nonsense	probably null
R6691:Igf2r	UTSW	17	12,689,008 (GRCm38)	missense	probably damaging	1.00
R6752:Igf2r	UTSW	17	12,714,944 (GRCm38)	missense	probably damaging	1.00
R6816:Igf2r	UTSW	17	12,714,082 (GRCm38)	missense	probably damaging	0.99
R6841:Igf2r	UTSW	17	12,703,376 (GRCm38)	missense	probably damaging	0.97
R6877:Igf2r	UTSW	17	12,697,341 (GRCm38)	missense	probably damaging	0.97
R6950:Igf2r	UTSW	17	12,718,718 (GRCm38)	missense	probably benign
R7030:Igf2r	UTSW	17	12,733,866 (GRCm38)	missense	probably damaging	1.00
R7038:Igf2r	UTSW	17	12,698,325 (GRCm38)	missense	probably benign	0.23
R7055:Igf2r	UTSW	17	12,704,323 (GRCm38)	missense	probably damaging	0.99
R7074:Igf2r	UTSW	17	12,714,116 (GRCm38)	missense	possibly damaging	0.57
R7348:Igf2r	UTSW	17	12,703,484 (GRCm38)	missense	probably damaging	0.99
R7413:Igf2r	UTSW	17	12,698,228 (GRCm38)	nonsense	probably null
R7463:Igf2r	UTSW	17	12,710,645 (GRCm38)	missense	probably benign	0.16
R7619:Igf2r	UTSW	17	12,698,273 (GRCm38)	missense	possibly damaging	0.88
R7730:Igf2r	UTSW	17	12,735,991 (GRCm38)	missense	probably damaging	0.98
R7733:Igf2r	UTSW	17	12,739,369 (GRCm38)	missense	possibly damaging	0.90
R7881:Igf2r	UTSW	17	12,748,704 (GRCm38)	missense	probably benign
R8022:Igf2r	UTSW	17	12,718,795 (GRCm38)	missense	probably damaging	1.00
R8138:Igf2r	UTSW	17	12,701,238 (GRCm38)	missense	probably benign	0.32
R8220:Igf2r	UTSW	17	12,692,071 (GRCm38)	missense	probably benign	0.22
R8305:Igf2r	UTSW	17	12,733,860 (GRCm38)	missense	probably benign
R8359:Igf2r	UTSW	17	12,683,861 (GRCm38)	missense	probably benign
R8500:Igf2r	UTSW	17	12,709,441 (GRCm38)	missense	probably damaging	0.99
R8510:Igf2r	UTSW	17	12,704,313 (GRCm38)	missense	probably benign	0.38
R8933:Igf2r	UTSW	17	12,704,637 (GRCm38)	missense	probably damaging	1.00
R8933:Igf2r	UTSW	17	12,701,244 (GRCm38)	missense	probably damaging	0.97
R8976:Igf2r	UTSW	17	12,726,772 (GRCm38)	missense	probably damaging	1.00
R8994:Igf2r	UTSW	17	12,716,650 (GRCm38)	missense	possibly damaging	0.87
R9059:Igf2r	UTSW	17	12,751,293 (GRCm38)	start codon destroyed	probably null
R9097:Igf2r	UTSW	17	12,691,213 (GRCm38)	missense	probably damaging	1.00
R9127:Igf2r	UTSW	17	12,739,351 (GRCm38)	missense	probably damaging	0.98
R9278:Igf2r	UTSW	17	12,695,353 (GRCm38)	missense	probably damaging	1.00
R9362:Igf2r	UTSW	17	12,722,175 (GRCm38)	missense	probably benign	0.02
R9371:Igf2r	UTSW	17	12,705,759 (GRCm38)	missense	possibly damaging	0.93
R9522:Igf2r	UTSW	17	12,698,328 (GRCm38)	missense	probably benign	0.26
R9567:Igf2r	UTSW	17	12,686,754 (GRCm38)	missense	probably damaging	1.00
R9665:Igf2r	UTSW	17	12,694,140 (GRCm38)	missense	probably benign	0.17
R9666:Igf2r	UTSW	17	12,726,701 (GRCm38)	missense	probably benign
X0028:Igf2r	UTSW	17	12,704,913 (GRCm38)	nonsense	probably null
Z1177:Igf2r	UTSW	17	12,697,399 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- TCTTTGATCATGCCAGCCAC -3'
(R):5'- GGAAAGGTGGTGGTCTCATC -3'

Sequencing Primer
(F):5'- TTCTCTATTAGTCTGGCTATAAGGC -3'
(R):5'- TCTCATCCAGAGTGAGCCTCAG -3'

Posted On

2014-08-25