Mutagenetix > Incidental Mutation

Incidental Mutation 'R2014:Espn'

222542

Institutional Source

Beutler Lab

Gene Symbol

Espn

Ensembl Gene

ENSMUSG00000028943

Gene Name

espin

Synonyms

MMRRC Submission

040023-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.280) question?

Stock #

R2014 (G1)

Quality Score

218

Status

Not validated

Chromosome

Chromosomal Location

152204788-152236828 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

G to T at 152217416 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000030785 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030785] [ENSMUST00000049305] [ENSMUST00000070018] [ENSMUST00000080042] [ENSMUST00000084114] [ENSMUST00000103196] [ENSMUST00000105653] [ENSMUST00000207676] [ENSMUST00000105655] [ENSMUST00000105654] [ENSMUST00000105656] [ENSMUST00000105659] [ENSMUST00000105658] [ENSMUST00000135185] [ENSMUST00000105657]

AlphaFold

Q9ET47

Predicted Effect

probably null
Transcript: ENSMUST00000030785

SMART Domains

Protein: ENSMUSP00000030785
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
ANK	35	64	3.26e0	SMART
ANK	69	99	1.15e0	SMART
ANK	103	133	2.58e-3	SMART
ANK	137	167	1.63e0	SMART
ANK	171	201	4.97e-5	SMART
ANK	205	235	3.08e-1	SMART
ANK	239	268	9.13e-4	SMART
ANK	271	300	2.15e0	SMART
ANK	304	334	2.08e3	SMART
low complexity region	377	395	N/A	INTRINSIC
low complexity region	428	465	N/A	INTRINSIC
low complexity region	605	629	N/A	INTRINSIC
WH2	669	686	4.82e-3	SMART
low complexity region	714	728	N/A	INTRINSIC
low complexity region	740	748	N/A	INTRINSIC
coiled coil region	772	848	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000049305

SMART Domains

Protein: ENSMUSP00000037982
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
WH2	26	43	4.82e-3	SMART
low complexity region	96	110	N/A	INTRINSIC
low complexity region	122	130	N/A	INTRINSIC
coiled coil region	154	230	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000070018

SMART Domains

Protein: ENSMUSP00000065545
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	101	138	N/A	INTRINSIC
low complexity region	267	291	N/A	INTRINSIC
low complexity region	304	313	N/A	INTRINSIC
WH2	322	339	4.82e-3	SMART
low complexity region	367	381	N/A	INTRINSIC
low complexity region	393	401	N/A	INTRINSIC
SCOP:d1eq1a_	432	499	4e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000080042

SMART Domains

Protein: ENSMUSP00000078951
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	101	138	N/A	INTRINSIC
low complexity region	186	210	N/A	INTRINSIC
WH2	250	267	4.82e-3	SMART
low complexity region	295	309	N/A	INTRINSIC
low complexity region	321	329	N/A	INTRINSIC
SCOP:d1eq1a_	360	427	2e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000084114

SMART Domains

Protein: ENSMUSP00000081131
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	101	138	N/A	INTRINSIC
low complexity region	267	291	N/A	INTRINSIC
WH2	331	348	4.82e-3	SMART
low complexity region	376	390	N/A	INTRINSIC
low complexity region	402	410	N/A	INTRINSIC
SCOP:d1eq1a_	441	508	6e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000103196

SMART Domains

Protein: ENSMUSP00000099485
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	98	135	N/A	INTRINSIC
low complexity region	183	207	N/A	INTRINSIC
low complexity region	220	229	N/A	INTRINSIC
WH2	238	255	4.82e-3	SMART
low complexity region	283	297	N/A	INTRINSIC
low complexity region	309	317	N/A	INTRINSIC
SCOP:d1eq1a_	348	415	2e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000105653

SMART Domains

Protein: ENSMUSP00000101278
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	28	52	N/A	INTRINSIC
low complexity region	65	74	N/A	INTRINSIC
WH2	83	100	4.82e-3	SMART
low complexity region	128	142	N/A	INTRINSIC
low complexity region	154	162	N/A	INTRINSIC
coiled coil region	186	262	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000136627

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000137937

Predicted Effect

probably benign
Transcript: ENSMUST00000207676

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150958

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000148075

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000156517

Predicted Effect

probably benign
Transcript: ENSMUST00000105655

SMART Domains

Protein: ENSMUSP00000101280
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	98	135	N/A	INTRINSIC
low complexity region	183	207	N/A	INTRINSIC
WH2	247	264	4.82e-3	SMART
low complexity region	292	306	N/A	INTRINSIC
low complexity region	318	326	N/A	INTRINSIC
SCOP:d1eq1a_	357	424	3e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000105654

SMART Domains

Protein: ENSMUSP00000101279
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	98	135	N/A	INTRINSIC
low complexity region	264	288	N/A	INTRINSIC
low complexity region	301	310	N/A	INTRINSIC
WH2	319	336	4.82e-3	SMART
low complexity region	364	378	N/A	INTRINSIC
low complexity region	390	398	N/A	INTRINSIC
SCOP:d1eq1a_	429	496	6e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000105656

SMART Domains

Protein: ENSMUSP00000101281
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	98	135	N/A	INTRINSIC
low complexity region	264	288	N/A	INTRINSIC
WH2	328	345	4.82e-3	SMART
low complexity region	373	387	N/A	INTRINSIC
low complexity region	399	407	N/A	INTRINSIC
SCOP:d1eq1a_	438	505	8e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000105659

SMART Domains

Protein: ENSMUSP00000101284
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
ANK	35	64	3.26e0	SMART
ANK	69	99	1.15e0	SMART
ANK	103	133	2.58e-3	SMART
ANK	137	167	1.63e0	SMART
ANK	171	201	4.97e-5	SMART
ANK	205	235	3.08e-1	SMART
ANK	239	268	9.13e-4	SMART
ANK	271	300	2.15e0	SMART
ANK	304	334	2.08e3	SMART
low complexity region	377	395	N/A	INTRINSIC
low complexity region	428	465	N/A	INTRINSIC
low complexity region	624	648	N/A	INTRINSIC
low complexity region	661	670	N/A	INTRINSIC
WH2	679	696	4.82e-3	SMART
low complexity region	724	738	N/A	INTRINSIC
low complexity region	750	758	N/A	INTRINSIC
coiled coil region	782	858	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000105658

SMART Domains

Protein: ENSMUSP00000101283
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
ANK	35	64	3.26e0	SMART
ANK	69	99	1.15e0	SMART
ANK	103	133	2.58e-3	SMART
ANK	137	167	1.63e0	SMART
ANK	171	201	4.97e-5	SMART
ANK	205	235	3.08e-1	SMART
ANK	239	268	9.13e-4	SMART
ANK	271	300	2.15e0	SMART
ANK	304	334	2.08e3	SMART
low complexity region	377	395	N/A	INTRINSIC
low complexity region	425	462	N/A	INTRINSIC
low complexity region	591	615	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
WH2	646	663	4.82e-3	SMART
low complexity region	691	705	N/A	INTRINSIC
low complexity region	717	725	N/A	INTRINSIC
coiled coil region	749	825	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000135185

SMART Domains

Protein: ENSMUSP00000122464
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
ANK	5	35	2.58e-3	SMART
ANK	39	69	1.63e0	SMART
ANK	73	103	4.97e-5	SMART
ANK	107	137	3.08e-1	SMART
ANK	141	170	9.13e-4	SMART
ANK	173	202	2.15e0	SMART
ANK	206	236	2.08e3	SMART
low complexity region	279	297	N/A	INTRINSIC
low complexity region	330	367	N/A	INTRINSIC
low complexity region	496	520	N/A	INTRINSIC
low complexity region	533	542	N/A	INTRINSIC
WH2	551	568	4.82e-3	SMART
low complexity region	596	610	N/A	INTRINSIC
low complexity region	622	630	N/A	INTRINSIC
coiled coil region	654	685	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000105657

SMART Domains

Protein: ENSMUSP00000101282
Gene: ENSMUSG00000028943

Domain	Start	End	E-Value	Type
low complexity region	50	68	N/A	INTRINSIC
low complexity region	101	138	N/A	INTRINSIC
low complexity region	186	210	N/A	INTRINSIC
low complexity region	223	232	N/A	INTRINSIC
WH2	241	258	4.82e-3	SMART
low complexity region	286	300	N/A	INTRINSIC
low complexity region	312	320	N/A	INTRINSIC
SCOP:d1eq1a_	351	418	2e-5	SMART

Coding Region Coverage

1x: 99.1%
3x: 98.5%
10x: 96.8%
20x: 93.9%

Validation Efficiency

96% (105/109)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. [provided by RefSeq, Nov 2009]
PHENOTYPE: Homozygotes for a spontaneous mutation exhibit progressive degeneration of both inner and outer hair cells, severe deafness, vestibular dysfunction, and poor mothering ability. Heterozygotes show a progressive, age-related hearing loss. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 108 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700122O11Rik	T	G	17: 48,347,723 (GRCm39)	T194P	possibly damaging	Het
Aadacl4fm5	A	T	4: 144,506,295 (GRCm39)	L132Q	probably damaging	Het
Acsbg2	T	A	17: 57,160,855 (GRCm39)	K263M	possibly damaging	Het
Adcy8	C	T	15: 64,639,727 (GRCm39)	G678S	probably benign	Het
Adgrl2	C	T	3: 148,532,111 (GRCm39)	G1041R	probably damaging	Het
Ahnak	T	C	19: 8,990,545 (GRCm39)	I3943T	probably damaging	Het
Aire	T	C	10: 77,878,792 (GRCm39)	D85G	probably damaging	Het
Alkbh8	C	T	9: 3,343,216 (GRCm39)	Q36*	probably null	Het
Amer3	T	C	1: 34,618,525 (GRCm39)		probably benign	Het
Angptl8	T	C	9: 21,748,358 (GRCm39)		probably null	Het
Ankmy1	T	C	1: 92,812,863 (GRCm39)	D482G	probably benign	Het
Apc	A	G	18: 34,448,644 (GRCm39)	I1813V	probably damaging	Het
Asb13	T	G	13: 3,699,512 (GRCm39)		probably null	Het
Blm	T	C	7: 80,152,147 (GRCm39)	E600G	probably damaging	Het
Cd163	G	T	6: 124,302,457 (GRCm39)	W1007L	probably damaging	Het
Cdr1	A	G	X: 60,228,420 (GRCm39)	F249L	probably benign	Het
Cp	A	G	3: 20,041,598 (GRCm39)	K44E	probably benign	Het
Crtap	C	A	9: 114,210,653 (GRCm39)		probably null	Het
Ctsk	A	G	3: 95,414,003 (GRCm39)	D250G	probably damaging	Het
Dcp2	T	C	18: 44,543,363 (GRCm39)	V307A	probably benign	Het
Dnah6	T	A	6: 73,150,402 (GRCm39)	D787V	probably damaging	Het
Dtx3l	G	A	16: 35,756,797 (GRCm39)	H129Y	probably benign	Het
Ece2	A	G	16: 20,461,067 (GRCm39)	T442A	probably benign	Het
Espl1	C	T	15: 102,231,149 (GRCm39)	R17*	probably null	Het
Fam20b	C	T	1: 156,533,511 (GRCm39)	R35Q	possibly damaging	Het
Fga	A	G	3: 82,940,064 (GRCm39)	I573V	probably damaging	Het
Fmo5	A	G	3: 97,542,998 (GRCm39)	K103E	possibly damaging	Het
Frem1	A	T	4: 82,924,089 (GRCm39)	V291D	probably damaging	Het
Gabbr1	A	G	17: 37,367,674 (GRCm39)		probably null	Het
Gjb6	T	C	14: 57,362,213 (GRCm39)	H16R	probably damaging	Het
Grina	T	C	15: 76,132,734 (GRCm39)	V167A	probably damaging	Het
Gulo	T	A	14: 66,246,496 (GRCm39)	M1L	probably benign	Het
Hcfc2	A	G	10: 82,574,814 (GRCm39)	N618D	probably benign	Het
Heatr5b	T	C	17: 79,121,613 (GRCm39)	D704G	probably damaging	Het
Hlcs	A	G	16: 94,063,599 (GRCm39)	V487A	probably benign	Het
Hps1	G	A	19: 42,750,951 (GRCm39)	P350S	probably benign	Het
Hspa9	A	T	18: 35,079,701 (GRCm39)	Y243N	probably damaging	Het
Igll1	A	G	16: 16,681,639 (GRCm39)	S39P	probably benign	Het
Kif21b	T	C	1: 136,076,020 (GRCm39)	F270L	probably damaging	Het
Kirrel1	C	T	3: 86,996,458 (GRCm39)	M380I	probably null	Het
Krt27	A	G	11: 99,240,318 (GRCm39)	V200A	probably benign	Het
Lama3	T	C	18: 12,657,778 (GRCm39)		probably benign	Het
Lmcd1	T	C	6: 112,305,702 (GRCm39)	W268R	probably damaging	Het
Lmo2	T	C	2: 103,811,407 (GRCm39)	Y147H	probably damaging	Het
Mamdc4	T	A	2: 25,453,584 (GRCm39)	D1195V	probably damaging	Het
Map2	T	C	1: 66,455,295 (GRCm39)	V1395A	possibly damaging	Het
Map3k20	C	T	2: 72,268,604 (GRCm39)	T537M	probably benign	Het
Mdga1	A	G	17: 30,068,287 (GRCm39)	S276P	probably damaging	Het
Mep1a	T	C	17: 43,808,797 (GRCm39)	N85D	probably benign	Het
Mettl16	A	G	11: 74,708,195 (GRCm39)	S425G	probably benign	Het
Mthfd1l	A	G	10: 3,997,894 (GRCm39)	T622A	probably benign	Het
Nbeal2	G	A	9: 110,463,139 (GRCm39)	L1309F	probably benign	Het
Nde1	A	T	16: 13,987,321 (GRCm39)		probably benign	Het
Nhsl1	A	T	10: 18,387,340 (GRCm39)	R205W	probably damaging	Het
Nlrc5	A	G	8: 95,252,138 (GRCm39)		probably benign	Het
Notch3	C	A	17: 32,376,974 (GRCm39)	E310D	probably benign	Het
Or2f1	A	G	6: 42,721,784 (GRCm39)	E271G	probably damaging	Het
Or4p19	T	C	2: 88,242,388 (GRCm39)	T205A	probably benign	Het
Or5ak24	T	A	2: 85,260,696 (GRCm39)	H159L	possibly damaging	Het
Or7a39	T	C	10: 78,715,222 (GRCm39)	I72T	possibly damaging	Het
Osbpl5	C	A	7: 143,295,429 (GRCm39)	C11F	probably damaging	Het
P4hb	T	C	11: 120,453,522 (GRCm39)	E381G	probably damaging	Het
Pax4	A	G	6: 28,446,209 (GRCm39)	Y95H	probably benign	Het
Pdia3	T	C	2: 121,265,301 (GRCm39)	V390A	probably damaging	Het
Pigv	A	C	4: 133,390,034 (GRCm39)	D49E	possibly damaging	Het
Pik3c2a	T	A	7: 115,950,166 (GRCm39)		probably null	Het
Plxnb1	T	A	9: 108,935,687 (GRCm39)		probably benign	Het
Polq	A	G	16: 36,898,728 (GRCm39)	T2163A	probably damaging	Het
Pou5f2	T	C	13: 78,173,972 (GRCm39)	S305P	probably benign	Het
Ppm1h	A	T	10: 122,756,630 (GRCm39)	H425L	possibly damaging	Het
Ppp1r13b	G	T	12: 111,800,222 (GRCm39)	D518E	probably benign	Het
Prf1	A	T	10: 61,139,674 (GRCm39)	D544V	probably benign	Het
Prl3b1	T	C	13: 27,431,948 (GRCm39)	F158L	probably benign	Het
Prss41	C	T	17: 24,056,464 (GRCm39)		probably null	Het
Prune2	T	G	19: 17,097,887 (GRCm39)	N1130K	probably damaging	Het
Ptgdr2	T	C	19: 10,917,789 (GRCm39)	F102S	probably damaging	Het
Ptprq	T	G	10: 107,503,283 (GRCm39)	K792Q	probably damaging	Het
Pttg1ip2	T	A	5: 5,505,964 (GRCm39)	I106L	probably benign	Het
Rcbtb2	T	C	14: 73,411,826 (GRCm39)		probably benign	Het
Rgs14	C	A	13: 55,531,513 (GRCm39)	S479*	probably null	Het
Sash1	A	T	10: 8,605,177 (GRCm39)	V1071D	probably benign	Het
Sdsl	G	A	5: 120,601,218 (GRCm39)	T18M	probably damaging	Het
Sepsecs	T	A	5: 52,804,966 (GRCm39)	Q365L	probably benign	Het
Sh2d4a	A	T	8: 68,783,735 (GRCm39)	Q223L	probably damaging	Het
Slc14a2	T	C	18: 78,193,601 (GRCm39)		probably benign	Het
Slc5a9	A	C	4: 111,753,546 (GRCm39)	S52A	possibly damaging	Het
Slc6a18	C	A	13: 73,823,844 (GRCm39)	V99L	probably benign	Het
Smarca2	T	C	19: 26,661,305 (GRCm39)	S967P	possibly damaging	Het
Tbc1d22a	C	T	15: 86,183,885 (GRCm39)	T248M	probably damaging	Het
Tcte1	A	T	17: 45,852,237 (GRCm39)	N490I	probably benign	Het
Tet3	T	C	6: 83,363,057 (GRCm39)	E705G	probably damaging	Het
Tfeb	T	A	17: 48,102,484 (GRCm39)	H450Q	probably damaging	Het
Tmem248	G	A	5: 130,260,653 (GRCm39)	E73K	probably damaging	Het
Trip12	A	T	1: 84,738,587 (GRCm39)	L756*	probably null	Het
Try5	C	T	6: 41,291,585 (GRCm39)		probably null	Het
Tsc1	A	T	2: 28,555,649 (GRCm39)		probably benign	Het
Tspear	G	A	10: 77,710,954 (GRCm39)		probably benign	Het
Ttc6	T	C	12: 57,623,003 (GRCm39)	I134T	possibly damaging	Het
Ttn	T	A	2: 76,585,640 (GRCm39)		probably null	Het
Ube3b	A	G	5: 114,549,210 (GRCm39)	E738G	probably damaging	Het
Usp36	T	C	11: 118,153,334 (GRCm39)		probably benign	Het
Vmn2r71	T	A	7: 85,269,845 (GRCm39)	M452K	probably benign	Het
Vps13b	T	C	15: 35,607,288 (GRCm39)	S1074P	probably damaging	Het
Vps13d	A	G	4: 144,835,078 (GRCm39)	S2757P	probably damaging	Het
Vwde	C	A	6: 13,208,337 (GRCm39)	G182C	possibly damaging	Het
Wdr33	T	C	18: 31,966,652 (GRCm39)	V164A	probably damaging	Het
Zkscan16	A	G	4: 58,956,525 (GRCm39)	Y269C	possibly damaging	Het
Zup1	A	G	10: 33,805,820 (GRCm39)	V437A	possibly damaging	Het

Other mutations in Espn

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00928:Espn	APN	4	152,220,059 (GRCm39)	missense	probably damaging	1.00
IGL01404:Espn	APN	4	152,222,901 (GRCm39)	missense	probably benign	0.03
IGL01576:Espn	APN	4	152,208,174 (GRCm39)	missense	probably damaging	1.00
R0015:Espn	UTSW	4	152,223,609 (GRCm39)	missense	possibly damaging	0.77
R1475:Espn	UTSW	4	152,218,728 (GRCm39)	missense	probably damaging	1.00
R1773:Espn	UTSW	4	152,212,686 (GRCm39)	missense	probably damaging	1.00
R1992:Espn	UTSW	4	152,213,012 (GRCm39)	critical splice acceptor site	probably null
R2049:Espn	UTSW	4	152,205,714 (GRCm39)	missense	probably damaging	0.99
R2281:Espn	UTSW	4	152,220,002 (GRCm39)	missense	possibly damaging	0.94
R4278:Espn	UTSW	4	152,218,874 (GRCm39)	missense	probably damaging	1.00
R4527:Espn	UTSW	4	152,220,106 (GRCm39)	missense	probably damaging	0.99
R4539:Espn	UTSW	4	152,218,665 (GRCm39)	nonsense	probably null
R4621:Espn	UTSW	4	152,215,709 (GRCm39)	missense	probably damaging	1.00
R4839:Espn	UTSW	4	152,222,961 (GRCm39)	missense	probably damaging	0.99
R4860:Espn	UTSW	4	152,223,303 (GRCm39)	missense	probably damaging	0.99
R4860:Espn	UTSW	4	152,223,303 (GRCm39)	missense	probably damaging	0.99
R4998:Espn	UTSW	4	152,220,040 (GRCm39)	missense	possibly damaging	0.94
R5412:Espn	UTSW	4	152,212,582 (GRCm39)	missense	probably damaging	1.00
R5570:Espn	UTSW	4	152,208,237 (GRCm39)	missense	probably damaging	1.00
R6549:Espn	UTSW	4	152,215,525 (GRCm39)	start codon destroyed	probably null	0.99
R6551:Espn	UTSW	4	152,213,223 (GRCm39)
R7124:Espn	UTSW	4	152,215,721 (GRCm39)	missense	probably benign	0.00
R7838:Espn	UTSW	4	152,215,738 (GRCm39)	missense	possibly damaging	0.95
R7863:Espn	UTSW	4	152,236,616 (GRCm39)	missense	probably damaging	0.99
R8236:Espn	UTSW	4	152,233,487 (GRCm39)	missense	probably damaging	1.00
R8948:Espn	UTSW	4	152,223,278 (GRCm39)	missense	probably damaging	1.00
R9234:Espn	UTSW	4	152,217,380 (GRCm39)	critical splice donor site	probably null
R9550:Espn	UTSW	4	152,215,534 (GRCm39)	missense	probably damaging	0.96
R9607:Espn	UTSW	4	152,219,939 (GRCm39)	missense	probably benign	0.00

Predicted Primers

Posted On

2014-08-25