Incidental Mutation 'R2014:Ttc6'
| ID |
222624 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ttc6
|
| Ensembl Gene |
ENSMUSG00000046782 |
| Gene Name |
tetratricopeptide repeat domain 6 |
| Synonyms |
LOC217602, Gm9813, EG639426, 4921506M07Rik, AU024163 |
| MMRRC Submission |
040023-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.099)
|
| Stock # |
R2014 (G1)
|
| Quality Score |
91 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
57610899-57784714 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 57623003 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 134
(I134T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000098946
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000101398]
[ENSMUST00000172939]
|
| AlphaFold |
G3UYY4 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000101398
AA Change: I134T
PolyPhen 2
Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000098946
Gene: ENSMUSG00000046782
AA Change: I134T
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
18 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
146 |
162 |
N/A |
INTRINSIC |
|
low complexity region
|
188 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
227 |
238 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000172939
AA Change: I134T
|
| SMART Domains |
Protein: ENSMUSP00000134273
Gene: ENSMUSG00000046782
AA Change: I134T
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
18 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
146 |
162 |
N/A |
INTRINSIC |
|
low complexity region
|
188 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
227 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
486 |
495 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
740 |
N/A |
INTRINSIC |
|
TPR
|
889 |
922 |
2e-4 |
SMART |
|
TPR
|
957 |
989 |
2.36e1 |
SMART |
|
TPR
|
990 |
1022 |
2.63e1 |
SMART |
|
TPR
|
1023 |
1056 |
9.39e-1 |
SMART |
|
TPR
|
1057 |
1090 |
3.78e-5 |
SMART |
|
Blast:TPR
|
1126 |
1157 |
1e-11 |
BLAST |
|
SEL1
|
1160 |
1192 |
3.39e1 |
SMART |
|
TPR
|
1160 |
1194 |
4.44e1 |
SMART |
|
TPR
|
1195 |
1228 |
7.87e0 |
SMART |
|
Blast:TPR
|
1229 |
1262 |
1e-11 |
BLAST |
|
TPR
|
1297 |
1330 |
1.24e0 |
SMART |
|
SEL1
|
1341 |
1372 |
9.26e-1 |
SMART |
|
TPR
|
1341 |
1374 |
3.45e-8 |
SMART |
|
TPR
|
1375 |
1407 |
8.76e-1 |
SMART |
|
TPR
|
1408 |
1441 |
1.45e-1 |
SMART |
|
TPR
|
1442 |
1475 |
1.36e1 |
SMART |
|
TPR
|
1476 |
1509 |
7.34e-3 |
SMART |
|
TPR
|
1513 |
1546 |
1.01e0 |
SMART |
|
TPR
|
1547 |
1580 |
2.55e-2 |
SMART |
|
TPR
|
1581 |
1617 |
2.43e1 |
SMART |
|
Blast:TPR
|
1618 |
1651 |
4e-12 |
BLAST |
|
TPR
|
1652 |
1685 |
7.87e0 |
SMART |
|
TPR
|
1686 |
1718 |
2.35e-1 |
SMART |
|
SEL1
|
1719 |
1750 |
1.21e2 |
SMART |
|
TPR
|
1719 |
1752 |
1.65e-5 |
SMART |
|
TPR
|
1753 |
1786 |
1.66e-1 |
SMART |
|
TPR
|
1787 |
1820 |
1.45e-1 |
SMART |
|
TPR
|
1821 |
1854 |
3.27e0 |
SMART |
|
| Meta Mutation Damage Score |
0.1276 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.9%
|
| Validation Efficiency |
96% (105/109) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700122O11Rik |
T |
G |
17: 48,347,723 (GRCm39) |
T194P |
possibly damaging |
Het |
| Aadacl4fm5 |
A |
T |
4: 144,506,295 (GRCm39) |
L132Q |
probably damaging |
Het |
| Acsbg2 |
T |
A |
17: 57,160,855 (GRCm39) |
K263M |
possibly damaging |
Het |
| Adcy8 |
C |
T |
15: 64,639,727 (GRCm39) |
G678S |
probably benign |
Het |
| Adgrl2 |
C |
T |
3: 148,532,111 (GRCm39) |
G1041R |
probably damaging |
Het |
| Ahnak |
T |
C |
19: 8,990,545 (GRCm39) |
I3943T |
probably damaging |
Het |
| Aire |
T |
C |
10: 77,878,792 (GRCm39) |
D85G |
probably damaging |
Het |
| Alkbh8 |
C |
T |
9: 3,343,216 (GRCm39) |
Q36* |
probably null |
Het |
| Amer3 |
T |
C |
1: 34,618,525 (GRCm39) |
|
probably benign |
Het |
| Angptl8 |
T |
C |
9: 21,748,358 (GRCm39) |
|
probably null |
Het |
| Ankmy1 |
T |
C |
1: 92,812,863 (GRCm39) |
D482G |
probably benign |
Het |
| Apc |
A |
G |
18: 34,448,644 (GRCm39) |
I1813V |
probably damaging |
Het |
| Asb13 |
T |
G |
13: 3,699,512 (GRCm39) |
|
probably null |
Het |
| Blm |
T |
C |
7: 80,152,147 (GRCm39) |
E600G |
probably damaging |
Het |
| Cd163 |
G |
T |
6: 124,302,457 (GRCm39) |
W1007L |
probably damaging |
Het |
| Cdr1 |
A |
G |
X: 60,228,420 (GRCm39) |
F249L |
probably benign |
Het |
| Cp |
A |
G |
3: 20,041,598 (GRCm39) |
K44E |
probably benign |
Het |
| Crtap |
C |
A |
9: 114,210,653 (GRCm39) |
|
probably null |
Het |
| Ctsk |
A |
G |
3: 95,414,003 (GRCm39) |
D250G |
probably damaging |
Het |
| Dcp2 |
T |
C |
18: 44,543,363 (GRCm39) |
V307A |
probably benign |
Het |
| Dnah6 |
T |
A |
6: 73,150,402 (GRCm39) |
D787V |
probably damaging |
Het |
| Dtx3l |
G |
A |
16: 35,756,797 (GRCm39) |
H129Y |
probably benign |
Het |
| Ece2 |
A |
G |
16: 20,461,067 (GRCm39) |
T442A |
probably benign |
Het |
| Espl1 |
C |
T |
15: 102,231,149 (GRCm39) |
R17* |
probably null |
Het |
| Espn |
G |
T |
4: 152,217,416 (GRCm39) |
|
probably null |
Het |
| Fam20b |
C |
T |
1: 156,533,511 (GRCm39) |
R35Q |
possibly damaging |
Het |
| Fga |
A |
G |
3: 82,940,064 (GRCm39) |
I573V |
probably damaging |
Het |
| Fmo5 |
A |
G |
3: 97,542,998 (GRCm39) |
K103E |
possibly damaging |
Het |
| Frem1 |
A |
T |
4: 82,924,089 (GRCm39) |
V291D |
probably damaging |
Het |
| Gabbr1 |
A |
G |
17: 37,367,674 (GRCm39) |
|
probably null |
Het |
| Gjb6 |
T |
C |
14: 57,362,213 (GRCm39) |
H16R |
probably damaging |
Het |
| Grina |
T |
C |
15: 76,132,734 (GRCm39) |
V167A |
probably damaging |
Het |
| Gulo |
T |
A |
14: 66,246,496 (GRCm39) |
M1L |
probably benign |
Het |
| Hcfc2 |
A |
G |
10: 82,574,814 (GRCm39) |
N618D |
probably benign |
Het |
| Heatr5b |
T |
C |
17: 79,121,613 (GRCm39) |
D704G |
probably damaging |
Het |
| Hlcs |
A |
G |
16: 94,063,599 (GRCm39) |
V487A |
probably benign |
Het |
| Hps1 |
G |
A |
19: 42,750,951 (GRCm39) |
P350S |
probably benign |
Het |
| Hspa9 |
A |
T |
18: 35,079,701 (GRCm39) |
Y243N |
probably damaging |
Het |
| Igll1 |
A |
G |
16: 16,681,639 (GRCm39) |
S39P |
probably benign |
Het |
| Kif21b |
T |
C |
1: 136,076,020 (GRCm39) |
F270L |
probably damaging |
Het |
| Kirrel1 |
C |
T |
3: 86,996,458 (GRCm39) |
M380I |
probably null |
Het |
| Krt27 |
A |
G |
11: 99,240,318 (GRCm39) |
V200A |
probably benign |
Het |
| Lama3 |
T |
C |
18: 12,657,778 (GRCm39) |
|
probably benign |
Het |
| Lmcd1 |
T |
C |
6: 112,305,702 (GRCm39) |
W268R |
probably damaging |
Het |
| Lmo2 |
T |
C |
2: 103,811,407 (GRCm39) |
Y147H |
probably damaging |
Het |
| Mamdc4 |
T |
A |
2: 25,453,584 (GRCm39) |
D1195V |
probably damaging |
Het |
| Map2 |
T |
C |
1: 66,455,295 (GRCm39) |
V1395A |
possibly damaging |
Het |
| Map3k20 |
C |
T |
2: 72,268,604 (GRCm39) |
T537M |
probably benign |
Het |
| Mdga1 |
A |
G |
17: 30,068,287 (GRCm39) |
S276P |
probably damaging |
Het |
| Mep1a |
T |
C |
17: 43,808,797 (GRCm39) |
N85D |
probably benign |
Het |
| Mettl16 |
A |
G |
11: 74,708,195 (GRCm39) |
S425G |
probably benign |
Het |
| Mthfd1l |
A |
G |
10: 3,997,894 (GRCm39) |
T622A |
probably benign |
Het |
| Nbeal2 |
G |
A |
9: 110,463,139 (GRCm39) |
L1309F |
probably benign |
Het |
| Nde1 |
A |
T |
16: 13,987,321 (GRCm39) |
|
probably benign |
Het |
| Nhsl1 |
A |
T |
10: 18,387,340 (GRCm39) |
R205W |
probably damaging |
Het |
| Nlrc5 |
A |
G |
8: 95,252,138 (GRCm39) |
|
probably benign |
Het |
| Notch3 |
C |
A |
17: 32,376,974 (GRCm39) |
E310D |
probably benign |
Het |
| Or2f1 |
A |
G |
6: 42,721,784 (GRCm39) |
E271G |
probably damaging |
Het |
| Or4p19 |
T |
C |
2: 88,242,388 (GRCm39) |
T205A |
probably benign |
Het |
| Or5ak24 |
T |
A |
2: 85,260,696 (GRCm39) |
H159L |
possibly damaging |
Het |
| Or7a39 |
T |
C |
10: 78,715,222 (GRCm39) |
I72T |
possibly damaging |
Het |
| Osbpl5 |
C |
A |
7: 143,295,429 (GRCm39) |
C11F |
probably damaging |
Het |
| P4hb |
T |
C |
11: 120,453,522 (GRCm39) |
E381G |
probably damaging |
Het |
| Pax4 |
A |
G |
6: 28,446,209 (GRCm39) |
Y95H |
probably benign |
Het |
| Pdia3 |
T |
C |
2: 121,265,301 (GRCm39) |
V390A |
probably damaging |
Het |
| Pigv |
A |
C |
4: 133,390,034 (GRCm39) |
D49E |
possibly damaging |
Het |
| Pik3c2a |
T |
A |
7: 115,950,166 (GRCm39) |
|
probably null |
Het |
| Plxnb1 |
T |
A |
9: 108,935,687 (GRCm39) |
|
probably benign |
Het |
| Polq |
A |
G |
16: 36,898,728 (GRCm39) |
T2163A |
probably damaging |
Het |
| Pou5f2 |
T |
C |
13: 78,173,972 (GRCm39) |
S305P |
probably benign |
Het |
| Ppm1h |
A |
T |
10: 122,756,630 (GRCm39) |
H425L |
possibly damaging |
Het |
| Ppp1r13b |
G |
T |
12: 111,800,222 (GRCm39) |
D518E |
probably benign |
Het |
| Prf1 |
A |
T |
10: 61,139,674 (GRCm39) |
D544V |
probably benign |
Het |
| Prl3b1 |
T |
C |
13: 27,431,948 (GRCm39) |
F158L |
probably benign |
Het |
| Prss41 |
C |
T |
17: 24,056,464 (GRCm39) |
|
probably null |
Het |
| Prune2 |
T |
G |
19: 17,097,887 (GRCm39) |
N1130K |
probably damaging |
Het |
| Ptgdr2 |
T |
C |
19: 10,917,789 (GRCm39) |
F102S |
probably damaging |
Het |
| Ptprq |
T |
G |
10: 107,503,283 (GRCm39) |
K792Q |
probably damaging |
Het |
| Pttg1ip2 |
T |
A |
5: 5,505,964 (GRCm39) |
I106L |
probably benign |
Het |
| Rcbtb2 |
T |
C |
14: 73,411,826 (GRCm39) |
|
probably benign |
Het |
| Rgs14 |
C |
A |
13: 55,531,513 (GRCm39) |
S479* |
probably null |
Het |
| Sash1 |
A |
T |
10: 8,605,177 (GRCm39) |
V1071D |
probably benign |
Het |
| Sdsl |
G |
A |
5: 120,601,218 (GRCm39) |
T18M |
probably damaging |
Het |
| Sepsecs |
T |
A |
5: 52,804,966 (GRCm39) |
Q365L |
probably benign |
Het |
| Sh2d4a |
A |
T |
8: 68,783,735 (GRCm39) |
Q223L |
probably damaging |
Het |
| Slc14a2 |
T |
C |
18: 78,193,601 (GRCm39) |
|
probably benign |
Het |
| Slc5a9 |
A |
C |
4: 111,753,546 (GRCm39) |
S52A |
possibly damaging |
Het |
| Slc6a18 |
C |
A |
13: 73,823,844 (GRCm39) |
V99L |
probably benign |
Het |
| Smarca2 |
T |
C |
19: 26,661,305 (GRCm39) |
S967P |
possibly damaging |
Het |
| Tbc1d22a |
C |
T |
15: 86,183,885 (GRCm39) |
T248M |
probably damaging |
Het |
| Tcte1 |
A |
T |
17: 45,852,237 (GRCm39) |
N490I |
probably benign |
Het |
| Tet3 |
T |
C |
6: 83,363,057 (GRCm39) |
E705G |
probably damaging |
Het |
| Tfeb |
T |
A |
17: 48,102,484 (GRCm39) |
H450Q |
probably damaging |
Het |
| Tmem248 |
G |
A |
5: 130,260,653 (GRCm39) |
E73K |
probably damaging |
Het |
| Trip12 |
A |
T |
1: 84,738,587 (GRCm39) |
L756* |
probably null |
Het |
| Try5 |
C |
T |
6: 41,291,585 (GRCm39) |
|
probably null |
Het |
| Tsc1 |
A |
T |
2: 28,555,649 (GRCm39) |
|
probably benign |
Het |
| Tspear |
G |
A |
10: 77,710,954 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
A |
2: 76,585,640 (GRCm39) |
|
probably null |
Het |
| Ube3b |
A |
G |
5: 114,549,210 (GRCm39) |
E738G |
probably damaging |
Het |
| Usp36 |
T |
C |
11: 118,153,334 (GRCm39) |
|
probably benign |
Het |
| Vmn2r71 |
T |
A |
7: 85,269,845 (GRCm39) |
M452K |
probably benign |
Het |
| Vps13b |
T |
C |
15: 35,607,288 (GRCm39) |
S1074P |
probably damaging |
Het |
| Vps13d |
A |
G |
4: 144,835,078 (GRCm39) |
S2757P |
probably damaging |
Het |
| Vwde |
C |
A |
6: 13,208,337 (GRCm39) |
G182C |
possibly damaging |
Het |
| Wdr33 |
T |
C |
18: 31,966,652 (GRCm39) |
V164A |
probably damaging |
Het |
| Zkscan16 |
A |
G |
4: 58,956,525 (GRCm39) |
Y269C |
possibly damaging |
Het |
| Zup1 |
A |
G |
10: 33,805,820 (GRCm39) |
V437A |
possibly damaging |
Het |
|
| Other mutations in Ttc6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL03278:Ttc6
|
APN |
12 |
57,668,812 (GRCm39) |
missense |
probably damaging |
0.99 |
|
polonius
|
UTSW |
12 |
57,704,928 (GRCm39) |
splice site |
probably null |
|
|
tybalt
|
UTSW |
12 |
57,720,542 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02802:Ttc6
|
UTSW |
12 |
57,622,654 (GRCm39) |
missense |
probably benign |
0.14 |
|
PIT4802001:Ttc6
|
UTSW |
12 |
57,772,462 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0698:Ttc6
|
UTSW |
12 |
57,720,002 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0988:Ttc6
|
UTSW |
12 |
57,735,435 (GRCm39) |
splice site |
probably benign |
|
|
R1290:Ttc6
|
UTSW |
12 |
57,707,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1338:Ttc6
|
UTSW |
12 |
57,663,155 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1468:Ttc6
|
UTSW |
12 |
57,721,463 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1468:Ttc6
|
UTSW |
12 |
57,721,463 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1481:Ttc6
|
UTSW |
12 |
57,783,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1488:Ttc6
|
UTSW |
12 |
57,696,301 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1558:Ttc6
|
UTSW |
12 |
57,733,132 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1570:Ttc6
|
UTSW |
12 |
57,721,549 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1619:Ttc6
|
UTSW |
12 |
57,784,454 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1819:Ttc6
|
UTSW |
12 |
57,741,286 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1826:Ttc6
|
UTSW |
12 |
57,707,033 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1863:Ttc6
|
UTSW |
12 |
57,760,881 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1872:Ttc6
|
UTSW |
12 |
57,751,338 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1887:Ttc6
|
UTSW |
12 |
57,720,044 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1937:Ttc6
|
UTSW |
12 |
57,663,109 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2056:Ttc6
|
UTSW |
12 |
57,784,479 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2058:Ttc6
|
UTSW |
12 |
57,784,479 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2059:Ttc6
|
UTSW |
12 |
57,784,479 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2152:Ttc6
|
UTSW |
12 |
57,752,338 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2179:Ttc6
|
UTSW |
12 |
57,719,904 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2275:Ttc6
|
UTSW |
12 |
57,749,084 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2432:Ttc6
|
UTSW |
12 |
57,668,821 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2474:Ttc6
|
UTSW |
12 |
57,622,713 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2853:Ttc6
|
UTSW |
12 |
57,622,967 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3848:Ttc6
|
UTSW |
12 |
57,723,932 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3853:Ttc6
|
UTSW |
12 |
57,775,335 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R3950:Ttc6
|
UTSW |
12 |
57,696,292 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3953:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3954:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3955:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3957:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4135:Ttc6
|
UTSW |
12 |
57,679,581 (GRCm39) |
intron |
probably benign |
|
|
R4387:Ttc6
|
UTSW |
12 |
57,689,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4577:Ttc6
|
UTSW |
12 |
57,623,441 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4747:Ttc6
|
UTSW |
12 |
57,721,478 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4779:Ttc6
|
UTSW |
12 |
57,776,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4803:Ttc6
|
UTSW |
12 |
57,775,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4871:Ttc6
|
UTSW |
12 |
57,749,142 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4898:Ttc6
|
UTSW |
12 |
57,707,026 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4930:Ttc6
|
UTSW |
12 |
57,720,609 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4946:Ttc6
|
UTSW |
12 |
57,689,926 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5257:Ttc6
|
UTSW |
12 |
57,749,061 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5303:Ttc6
|
UTSW |
12 |
57,622,606 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5385:Ttc6
|
UTSW |
12 |
57,689,821 (GRCm39) |
splice site |
probably null |
|
|
R5402:Ttc6
|
UTSW |
12 |
57,783,817 (GRCm39) |
nonsense |
probably null |
|
|
R5428:Ttc6
|
UTSW |
12 |
57,736,620 (GRCm39) |
missense |
probably null |
0.98 |
|
R5436:Ttc6
|
UTSW |
12 |
57,721,380 (GRCm39) |
splice site |
probably null |
|
|
R5646:Ttc6
|
UTSW |
12 |
57,622,805 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5697:Ttc6
|
UTSW |
12 |
57,724,000 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5792:Ttc6
|
UTSW |
12 |
57,719,990 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5808:Ttc6
|
UTSW |
12 |
57,664,397 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5842:Ttc6
|
UTSW |
12 |
57,783,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5935:Ttc6
|
UTSW |
12 |
57,720,590 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6144:Ttc6
|
UTSW |
12 |
57,719,886 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6155:Ttc6
|
UTSW |
12 |
57,784,402 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6283:Ttc6
|
UTSW |
12 |
57,749,048 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6371:Ttc6
|
UTSW |
12 |
57,775,249 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6715:Ttc6
|
UTSW |
12 |
57,721,556 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6738:Ttc6
|
UTSW |
12 |
57,735,426 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6795:Ttc6
|
UTSW |
12 |
57,751,199 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6959:Ttc6
|
UTSW |
12 |
57,704,928 (GRCm39) |
splice site |
probably null |
|
|
R7053:Ttc6
|
UTSW |
12 |
57,707,318 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7125:Ttc6
|
UTSW |
12 |
57,623,125 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7259:Ttc6
|
UTSW |
12 |
57,622,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7304:Ttc6
|
UTSW |
12 |
57,622,837 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7369:Ttc6
|
UTSW |
12 |
57,719,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7409:Ttc6
|
UTSW |
12 |
57,743,772 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7429:Ttc6
|
UTSW |
12 |
57,704,888 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7430:Ttc6
|
UTSW |
12 |
57,704,888 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7492:Ttc6
|
UTSW |
12 |
57,719,922 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7535:Ttc6
|
UTSW |
12 |
57,623,305 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7866:Ttc6
|
UTSW |
12 |
57,721,435 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7901:Ttc6
|
UTSW |
12 |
57,735,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7944:Ttc6
|
UTSW |
12 |
57,707,229 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7945:Ttc6
|
UTSW |
12 |
57,707,229 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7965:Ttc6
|
UTSW |
12 |
57,720,542 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8062:Ttc6
|
UTSW |
12 |
57,783,764 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8119:Ttc6
|
UTSW |
12 |
57,752,429 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8142:Ttc6
|
UTSW |
12 |
57,744,258 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8154:Ttc6
|
UTSW |
12 |
57,776,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Ttc6
|
UTSW |
12 |
57,720,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Ttc6
|
UTSW |
12 |
57,707,077 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8343:Ttc6
|
UTSW |
12 |
57,707,282 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R8696:Ttc6
|
UTSW |
12 |
57,784,492 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8875:Ttc6
|
UTSW |
12 |
57,776,194 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8875:Ttc6
|
UTSW |
12 |
57,751,199 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8876:Ttc6
|
UTSW |
12 |
57,784,489 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8924:Ttc6
|
UTSW |
12 |
57,697,790 (GRCm39) |
nonsense |
probably null |
|
|
R8944:Ttc6
|
UTSW |
12 |
57,689,826 (GRCm39) |
missense |
|
|
|
R8956:Ttc6
|
UTSW |
12 |
57,775,196 (GRCm39) |
nonsense |
probably null |
|
|
R9009:Ttc6
|
UTSW |
12 |
57,744,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9020:Ttc6
|
UTSW |
12 |
57,752,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9051:Ttc6
|
UTSW |
12 |
57,783,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9232:Ttc6
|
UTSW |
12 |
57,776,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9291:Ttc6
|
UTSW |
12 |
57,622,730 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9304:Ttc6
|
UTSW |
12 |
57,776,117 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9309:Ttc6
|
UTSW |
12 |
57,753,649 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9331:Ttc6
|
UTSW |
12 |
57,720,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9398:Ttc6
|
UTSW |
12 |
57,784,404 (GRCm39) |
nonsense |
probably null |
|
|
R9430:Ttc6
|
UTSW |
12 |
57,733,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9632:Ttc6
|
UTSW |
12 |
57,664,299 (GRCm39) |
missense |
probably benign |
|
|
R9688:Ttc6
|
UTSW |
12 |
57,720,602 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9732:Ttc6
|
UTSW |
12 |
57,775,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9740:Ttc6
|
UTSW |
12 |
57,736,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9749:Ttc6
|
UTSW |
12 |
57,701,559 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0021:Ttc6
|
UTSW |
12 |
57,622,904 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0058:Ttc6
|
UTSW |
12 |
57,753,637 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Ttc6
|
UTSW |
12 |
57,744,161 (GRCm39) |
missense |
probably benign |
0.08 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGCACGTTATGAAGACCAG -3'
(R):5'- AATATCGCTGCTCAGGCTG -3'
Sequencing Primer
(F):5'- AGAAGGGGCACGTGTCCTG -3'
(R):5'- TGCTCAGGCTGGACAAGG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation