Mutagenetix > Incidental Mutation

Incidental Mutation 'R1988:Dnah3'

222852

Institutional Source

Beutler Lab

Gene Symbol

Dnah3

Ensembl Gene

ENSMUSG00000052273

Gene Name

dynein, axonemal, heavy chain 3

Synonyms

MMRRC Submission

040000-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.089) question?

Stock #

R1988 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

119922671-120095280 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 119967570 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Serine at position 2478 (T2478S)

Ref Sequence

ENSEMBL: ENSMUSP00000042857 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046993] [ENSMUST00000209154] [ENSMUST00000213149]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000046993
AA Change: T2478S

PolyPhen 2 Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000042857
Gene: ENSMUSG00000052273
AA Change: T2478S

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	805	820	N/A	INTRINSIC
Pfam:DHC_N2	826	1235	3.3e-144	PFAM
AAA	1388	1527	1.59e-1	SMART
low complexity region	1594	1606	N/A	INTRINSIC
Blast:AAA	1669	1897	9e-84	BLAST
AAA	2033	2180	1.33e-3	SMART
Pfam:AAA_8	2362	2632	1.5e-63	PFAM
Pfam:MT	2644	2994	7.4e-52	PFAM
Pfam:AAA_9	3015	3240	3.5e-92	PFAM
low complexity region	3338	3349	N/A	INTRINSIC
Pfam:Dynein_heavy	3376	4079	4.4e-285	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000157547

Predicted Effect

unknown
Transcript: ENSMUST00000208910
AA Change: T91S

Predicted Effect

possibly damaging
Transcript: ENSMUST00000209154
AA Change: T2467S

PolyPhen 2 Score 0.890 (Sensitivity: 0.82; Specificity: 0.94)

Predicted Effect

probably benign
Transcript: ENSMUST00000213149

Meta Mutation Damage Score

0.0814

Coding Region Coverage

1x: 99.2%
3x: 98.4%
10x: 96.6%
20x: 93.1%

Validation Efficiency

96% (79/82)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 76 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700034J05Rik	T	A	6: 146,952,896 (GRCm38)	D216V	possibly damaging	Het
2610021A01Rik	C	T	7: 41,626,657 (GRCm38)	R595*	probably null	Het
Adgrl3	A	G	5: 81,688,567 (GRCm38)	D724G	probably damaging	Het
Akap6	T	C	12: 53,140,795 (GRCm38)	F1664S	possibly damaging	Het
Akt1	T	C	12: 112,655,151 (GRCm38)	I404V	probably benign	Het
Anxa13	T	A	15: 58,341,948 (GRCm38)		noncoding transcript	Het
Atoh1	T	C	6: 64,729,633 (GRCm38)	V104A	probably benign	Het
Brwd1	T	C	16: 96,021,237 (GRCm38)	D1256G	probably damaging	Het
C9	ATTTT	ATTT	15: 6,483,138 (GRCm38)		probably null	Het
Cd164	A	G	10: 41,523,181 (GRCm38)	T89A	probably benign	Het
Cep350	G	C	1: 155,933,104 (GRCm38)	N575K	possibly damaging	Het
Chrm5	A	G	2: 112,480,252 (GRCm38)	V173A	probably damaging	Het
Cnot1	A	G	8: 95,741,944 (GRCm38)	V1417A	possibly damaging	Het
Cntnap3	T	C	13: 64,758,390 (GRCm38)	T801A	probably damaging	Het
Cntnap5b	A	C	1: 100,072,140 (GRCm38)	K208Q	possibly damaging	Het
Crx	A	T	7: 15,869,347 (GRCm38)	V107D	possibly damaging	Het
Csrnp2	A	G	15: 100,489,440 (GRCm38)	F49S	probably damaging	Het
Ctbp1	A	G	5: 33,250,904 (GRCm38)	L228P	possibly damaging	Het
Ctdp1	A	T	18: 80,449,401 (GRCm38)	D626E	possibly damaging	Het
Cyp1a2	T	C	9: 57,682,286 (GRCm38)	T82A	possibly damaging	Het
Dnah5	T	C	15: 28,343,591 (GRCm38)	I2379T	probably damaging	Het
Dnah6	A	G	6: 73,092,192 (GRCm38)	I2504T	probably damaging	Het
Dnase1l2	A	C	17: 24,441,651 (GRCm38)	W138G	probably damaging	Het
Dopey2	T	A	16: 93,766,173 (GRCm38)	I855N	probably damaging	Het
Dsc3	T	A	18: 19,965,846 (GRCm38)	N759Y	possibly damaging	Het
Dtx2	C	T	5: 136,032,293 (GRCm38)	R510*	probably null	Het
Fat4	G	T	3: 38,887,115 (GRCm38)	M52I	probably benign	Het
Fat4	G	A	3: 38,996,090 (GRCm38)	E4034K	probably damaging	Het
Fezf2	T	C	14: 12,344,350 (GRCm38)	K279R	probably damaging	Het
Fsip2	G	T	2: 82,976,517 (GRCm38)	W1060L	possibly damaging	Het
G6pc	T	A	11: 101,367,942 (GRCm38)	I49N	probably damaging	Het
Gars	A	G	6: 55,077,772 (GRCm38)	E688G	probably null	Het
Gdf11	T	C	10: 128,885,242 (GRCm38)	N361S	probably benign	Het
Gli3	A	C	13: 15,726,380 (GRCm38)	M1451L	probably benign	Het
Heatr3	T	C	8: 88,150,317 (GRCm38)	I329T	probably benign	Het
Herc3	T	G	6: 58,884,975 (GRCm38)		probably null	Het
Hrnr	A	G	3: 93,332,604 (GRCm38)	N3383S	unknown	Het
Igsf3	A	T	3: 101,431,296 (GRCm38)	I309F	probably benign	Het
Kif21b	C	T	1: 136,152,264 (GRCm38)	R513W	probably damaging	Het
Kif7	G	T	7: 79,699,241 (GRCm38)	H1195Q	probably benign	Het
Lpcat4	T	C	2: 112,242,542 (GRCm38)	V182A	possibly damaging	Het
Map3k21	T	A	8: 125,927,555 (GRCm38)	I371N	probably benign	Het
Mns1	G	A	9: 72,448,759 (GRCm38)		probably null	Het
Myo3a	A	G	2: 22,578,128 (GRCm38)	T465A	possibly damaging	Het
Nlrc4	A	T	17: 74,426,943 (GRCm38)	S992T	probably benign	Het
Notch4	G	A	17: 34,587,588 (GRCm38)	G1833E	possibly damaging	Het
Olfr160	A	T	9: 37,711,697 (GRCm38)	I194K	possibly damaging	Het
Olfr467	A	T	7: 107,814,700 (GRCm38)	I39L	probably benign	Het
Olfr600	T	A	7: 103,346,109 (GRCm38)	Y273F	possibly damaging	Het
Olfr666	T	C	7: 104,892,903 (GRCm38)	T242A	probably damaging	Het
Olfr998	G	A	2: 85,590,641 (GRCm38)	V34I	probably benign	Het
Pcdh9	G	A	14: 93,888,305 (GRCm38)	P143L	probably damaging	Het
Pik3cd	T	A	4: 149,663,203 (GRCm38)	T28S	probably damaging	Het
Pkd1	G	T	17: 24,576,592 (GRCm38)		probably null	Het
Plk4	A	T	3: 40,805,817 (GRCm38)	S383C	possibly damaging	Het
Plxna2	T	C	1: 194,643,989 (GRCm38)	L77P	probably damaging	Het
Ppm1f	T	C	16: 16,923,666 (GRCm38)	S335P	probably damaging	Het
Prr16	C	T	18: 51,303,277 (GRCm38)	P276L	probably damaging	Het
Rilp	A	G	11: 75,510,933 (GRCm38)		probably null	Het
Rspry1	A	G	8: 94,632,054 (GRCm38)		probably null	Het
Serpinb9b	T	C	13: 33,029,559 (GRCm38)	V33A	probably benign	Het
Slc4a10	C	A	2: 62,268,204 (GRCm38)	Q561K	probably damaging	Het
Smyd5	T	C	6: 85,438,136 (GRCm38)	I42T	possibly damaging	Het
Stk17b	T	C	1: 53,761,082 (GRCm38)	N246D	probably damaging	Het
Suco	T	C	1: 161,818,811 (GRCm38)		probably null	Het
Tcrg-C3	C	A	13: 19,260,994 (GRCm38)	F37L	probably damaging	Het
Tecpr1	C	T	5: 144,204,697 (GRCm38)	V785M	possibly damaging	Het
Telo2	C	T	17: 25,101,668 (GRCm38)	V756I	probably benign	Het
Tgm1	C	T	14: 55,705,577 (GRCm38)	R602H	probably benign	Het
Timeless	A	G	10: 128,244,187 (GRCm38)	T402A	probably damaging	Het
Tnfaip2	T	A	12: 111,449,891 (GRCm38)		probably null	Het
Trim5	A	G	7: 104,265,621 (GRCm38)	S414P	probably damaging	Het
Txnip	A	G	3: 96,559,750 (GRCm38)	T247A	possibly damaging	Het
Vmn1r174	A	T	7: 23,754,625 (GRCm38)	T239S	probably damaging	Het
Vmn1r231	T	A	17: 20,889,950 (GRCm38)	E234D	probably damaging	Het
Zranb3	A	T	1: 127,959,743 (GRCm38)	N982K	probably benign	Het

Other mutations in Dnah3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00650:Dnah3	APN	7	119,938,905 (GRCm38)	missense	possibly damaging	0.88
IGL01095:Dnah3	APN	7	119,951,597 (GRCm38)	missense	probably benign	0.02
IGL01329:Dnah3	APN	7	120,022,941 (GRCm38)	missense	probably damaging	1.00
IGL01380:Dnah3	APN	7	119,926,564 (GRCm38)	missense	probably damaging	1.00
IGL01410:Dnah3	APN	7	119,967,720 (GRCm38)	missense	possibly damaging	0.91
IGL01487:Dnah3	APN	7	119,965,530 (GRCm38)	nonsense	probably null
IGL01843:Dnah3	APN	7	119,943,575 (GRCm38)	missense	probably benign	0.12
IGL01929:Dnah3	APN	7	119,951,651 (GRCm38)	nonsense	probably null
IGL01994:Dnah3	APN	7	119,951,214 (GRCm38)	missense	possibly damaging	0.58
IGL02115:Dnah3	APN	7	120,029,054 (GRCm38)	missense	probably damaging	1.00
IGL02273:Dnah3	APN	7	119,951,271 (GRCm38)	missense	probably damaging	1.00
IGL02299:Dnah3	APN	7	119,967,579 (GRCm38)	missense	probably benign	0.39
IGL02421:Dnah3	APN	7	119,950,992 (GRCm38)	missense	possibly damaging	0.87
IGL02514:Dnah3	APN	7	119,966,247 (GRCm38)	missense	probably damaging	1.00
IGL02596:Dnah3	APN	7	119,938,914 (GRCm38)	missense	probably benign	0.19
IGL02716:Dnah3	APN	7	119,937,023 (GRCm38)	missense	probably damaging	0.97
IGL02738:Dnah3	APN	7	119,965,497 (GRCm38)	missense	probably benign
IGL03404:Dnah3	APN	7	119,938,977 (GRCm38)	missense	probably damaging	1.00
R0964_Dnah3_480	UTSW	7	119,952,739 (GRCm38)	splice site	probably benign
R1778_Dnah3_238	UTSW	7	120,078,402 (GRCm38)	missense	probably damaging	1.00
R4658_Dnah3_599	UTSW	7	119,950,651 (GRCm38)	missense	probably damaging	1.00
BB004:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
BB014:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
R0011:Dnah3	UTSW	7	120,019,701 (GRCm38)	missense	probably damaging	1.00
R0195:Dnah3	UTSW	7	120,077,775 (GRCm38)	critical splice donor site	probably null
R0241:Dnah3	UTSW	7	119,922,730 (GRCm38)	missense	probably damaging	1.00
R0241:Dnah3	UTSW	7	119,922,730 (GRCm38)	missense	probably damaging	1.00
R0312:Dnah3	UTSW	7	120,045,659 (GRCm38)	missense	probably damaging	1.00
R0316:Dnah3	UTSW	7	119,965,659 (GRCm38)	missense	possibly damaging	0.94
R0370:Dnah3	UTSW	7	120,086,720 (GRCm38)	missense	possibly damaging	0.91
R0426:Dnah3	UTSW	7	119,943,572 (GRCm38)	missense	probably benign	0.11
R0525:Dnah3	UTSW	7	119,928,754 (GRCm38)	missense	probably damaging	1.00
R0625:Dnah3	UTSW	7	120,071,887 (GRCm38)	missense	possibly damaging	0.68
R0627:Dnah3	UTSW	7	120,020,915 (GRCm38)	missense	probably damaging	1.00
R0632:Dnah3	UTSW	7	119,967,905 (GRCm38)	missense	probably benign	0.11
R0928:Dnah3	UTSW	7	120,030,051 (GRCm38)	missense	probably damaging	1.00
R0964:Dnah3	UTSW	7	119,952,739 (GRCm38)	splice site	probably benign
R0972:Dnah3	UTSW	7	120,035,340 (GRCm38)	splice site	probably null
R1066:Dnah3	UTSW	7	120,061,009 (GRCm38)	missense	probably damaging	1.00
R1082:Dnah3	UTSW	7	120,078,445 (GRCm38)	missense	probably damaging	1.00
R1127:Dnah3	UTSW	7	119,923,030 (GRCm38)	missense	probably damaging	1.00
R1132:Dnah3	UTSW	7	119,939,004 (GRCm38)	missense	possibly damaging	0.50
R1222:Dnah3	UTSW	7	120,090,676 (GRCm38)	missense	probably benign	0.28
R1420:Dnah3	UTSW	7	119,951,979 (GRCm38)	missense	probably damaging	0.99
R1456:Dnah3	UTSW	7	120,047,630 (GRCm38)	missense	probably damaging	1.00
R1472:Dnah3	UTSW	7	120,070,958 (GRCm38)	missense	probably benign	0.12
R1617:Dnah3	UTSW	7	120,089,946 (GRCm38)	missense	probably benign	0.01
R1624:Dnah3	UTSW	7	120,019,695 (GRCm38)	missense	probably damaging	0.99
R1654:Dnah3	UTSW	7	119,926,449 (GRCm38)	missense	probably damaging	1.00
R1673:Dnah3	UTSW	7	119,971,179 (GRCm38)	nonsense	probably null
R1677:Dnah3	UTSW	7	119,928,740 (GRCm38)	missense	probably damaging	1.00
R1687:Dnah3	UTSW	7	120,045,786 (GRCm38)	splice site	probably null
R1711:Dnah3	UTSW	7	120,078,571 (GRCm38)	missense	probably damaging	1.00
R1738:Dnah3	UTSW	7	120,035,359 (GRCm38)	missense	probably damaging	1.00
R1778:Dnah3	UTSW	7	120,078,402 (GRCm38)	missense	probably damaging	1.00
R1866:Dnah3	UTSW	7	119,928,856 (GRCm38)	splice site	probably null
R1883:Dnah3	UTSW	7	120,077,919 (GRCm38)	missense	probably benign	0.06
R1894:Dnah3	UTSW	7	120,086,334 (GRCm38)	missense	probably benign	0.05
R1929:Dnah3	UTSW	7	119,975,129 (GRCm38)	missense	probably benign	0.10
R1988:Dnah3	UTSW	7	119,967,959 (GRCm38)	missense	probably damaging	0.99
R2010:Dnah3	UTSW	7	120,095,177 (GRCm38)	start codon destroyed	probably benign	0.00
R2022:Dnah3	UTSW	7	119,951,242 (GRCm38)	missense	probably damaging	1.00
R2026:Dnah3	UTSW	7	120,039,406 (GRCm38)	missense	probably damaging	1.00
R2063:Dnah3	UTSW	7	119,951,909 (GRCm38)	missense	probably damaging	0.96
R2131:Dnah3	UTSW	7	119,967,759 (GRCm38)	missense	possibly damaging	0.93
R2152:Dnah3	UTSW	7	119,952,013 (GRCm38)	missense	probably benign	0.02
R2199:Dnah3	UTSW	7	119,951,569 (GRCm38)	missense	possibly damaging	0.89
R2271:Dnah3	UTSW	7	119,975,129 (GRCm38)	missense	probably benign	0.10
R2350:Dnah3	UTSW	7	120,045,788 (GRCm38)	splice site	probably null
R2567:Dnah3	UTSW	7	119,952,697 (GRCm38)	missense	possibly damaging	0.83
R2848:Dnah3	UTSW	7	119,967,938 (GRCm38)	missense	probably benign	0.01
R2902:Dnah3	UTSW	7	119,951,499 (GRCm38)	missense	possibly damaging	0.61
R2926:Dnah3	UTSW	7	119,951,115 (GRCm38)	missense	probably damaging	1.00
R2944:Dnah3	UTSW	7	119,951,110 (GRCm38)	missense	probably damaging	1.00
R3022:Dnah3	UTSW	7	120,078,481 (GRCm38)	missense	possibly damaging	0.93
R3401:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3402:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3403:Dnah3	UTSW	7	119,967,656 (GRCm38)	missense	probably benign	0.00
R3919:Dnah3	UTSW	7	119,951,080 (GRCm38)	missense	probably damaging	1.00
R3972:Dnah3	UTSW	7	120,086,720 (GRCm38)	missense	probably damaging	0.99
R4162:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4184:Dnah3	UTSW	7	120,083,293 (GRCm38)	missense	probably damaging	1.00
R4198:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4199:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4200:Dnah3	UTSW	7	119,922,838 (GRCm38)	missense	probably damaging	1.00
R4239:Dnah3	UTSW	7	120,029,025 (GRCm38)	nonsense	probably null
R4478:Dnah3	UTSW	7	120,071,863 (GRCm38)	missense	probably benign	0.00
R4579:Dnah3	UTSW	7	120,009,331 (GRCm38)	missense	probably damaging	1.00
R4600:Dnah3	UTSW	7	120,089,946 (GRCm38)	missense	probably benign
R4649:Dnah3	UTSW	7	120,047,698 (GRCm38)	missense	probably damaging	1.00
R4658:Dnah3	UTSW	7	119,950,651 (GRCm38)	missense	probably damaging	1.00
R4728:Dnah3	UTSW	7	120,059,366 (GRCm38)	missense	probably damaging	0.99
R4739:Dnah3	UTSW	7	120,077,946 (GRCm38)	missense	possibly damaging	0.54
R4758:Dnah3	UTSW	7	120,079,406 (GRCm38)	missense	probably benign	0.00
R4785:Dnah3	UTSW	7	119,967,824 (GRCm38)	missense	probably benign	0.29
R4789:Dnah3	UTSW	7	120,011,072 (GRCm38)	missense	probably damaging	1.00
R4930:Dnah3	UTSW	7	119,951,681 (GRCm38)	nonsense	probably null
R4935:Dnah3	UTSW	7	120,016,477 (GRCm38)	nonsense	probably null
R4946:Dnah3	UTSW	7	119,931,560 (GRCm38)	missense	probably damaging	1.00
R4981:Dnah3	UTSW	7	119,956,201 (GRCm38)	missense	probably benign	0.03
R4984:Dnah3	UTSW	7	119,928,779 (GRCm38)	missense	probably benign	0.04
R5025:Dnah3	UTSW	7	120,071,905 (GRCm38)	missense	probably benign	0.02
R5046:Dnah3	UTSW	7	119,951,580 (GRCm38)	missense	probably damaging	1.00
R5056:Dnah3	UTSW	7	120,020,946 (GRCm38)	missense	probably damaging	1.00
R5068:Dnah3	UTSW	7	120,032,790 (GRCm38)	missense	probably benign
R5069:Dnah3	UTSW	7	120,032,790 (GRCm38)	missense	probably benign
R5154:Dnah3	UTSW	7	119,952,419 (GRCm38)	missense	probably damaging	1.00
R5208:Dnah3	UTSW	7	120,032,638 (GRCm38)	missense	probably damaging	1.00
R5323:Dnah3	UTSW	7	120,021,011 (GRCm38)	missense	probably damaging	1.00
R5330:Dnah3	UTSW	7	119,943,648 (GRCm38)	missense	probably benign	0.00
R5385:Dnah3	UTSW	7	119,924,903 (GRCm38)	missense	probably damaging	1.00
R5391:Dnah3	UTSW	7	120,090,076 (GRCm38)	missense	probably benign	0.02
R5564:Dnah3	UTSW	7	119,971,466 (GRCm38)	critical splice donor site	probably null
R5594:Dnah3	UTSW	7	119,971,621 (GRCm38)	missense	possibly damaging	0.89
R5610:Dnah3	UTSW	7	119,939,065 (GRCm38)	splice site	probably null
R5673:Dnah3	UTSW	7	119,951,589 (GRCm38)	missense	possibly damaging	0.91
R5678:Dnah3	UTSW	7	120,077,851 (GRCm38)	missense	probably benign	0.00
R5737:Dnah3	UTSW	7	120,059,198 (GRCm38)	missense	probably benign	0.03
R5766:Dnah3	UTSW	7	119,978,222 (GRCm38)	missense	probably damaging	1.00
R5769:Dnah3	UTSW	7	120,089,952 (GRCm38)	nonsense	probably null
R5789:Dnah3	UTSW	7	119,943,599 (GRCm38)	missense	possibly damaging	0.70
R5791:Dnah3	UTSW	7	119,931,473 (GRCm38)	missense	probably benign	0.00
R5841:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5843:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5844:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5846:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5851:Dnah3	UTSW	7	120,039,362 (GRCm38)	missense	possibly damaging	0.51
R5853:Dnah3	UTSW	7	119,938,833 (GRCm38)	missense	probably damaging	1.00
R5857:Dnah3	UTSW	7	119,951,021 (GRCm38)	utr 3 prime	probably benign
R5865:Dnah3	UTSW	7	119,975,108 (GRCm38)	missense	probably benign	0.00
R5885:Dnah3	UTSW	7	120,069,704 (GRCm38)	missense	probably benign	0.10
R5898:Dnah3	UTSW	7	120,078,501 (GRCm38)	missense	probably benign	0.37
R5917:Dnah3	UTSW	7	120,016,526 (GRCm38)	missense	probably damaging	1.00
R5964:Dnah3	UTSW	7	119,922,880 (GRCm38)	missense	probably benign	0.00
R5990:Dnah3	UTSW	7	120,073,541 (GRCm38)	missense	probably benign
R6004:Dnah3	UTSW	7	120,086,297 (GRCm38)	missense	probably benign	0.10
R6033:Dnah3	UTSW	7	120,071,647 (GRCm38)	missense	probably benign	0.00
R6033:Dnah3	UTSW	7	120,071,647 (GRCm38)	missense	probably benign	0.00
R6045:Dnah3	UTSW	7	119,967,522 (GRCm38)	missense	probably damaging	0.99
R6056:Dnah3	UTSW	7	120,030,031 (GRCm38)	missense	probably damaging	1.00
R6133:Dnah3	UTSW	7	120,086,246 (GRCm38)	missense	probably benign	0.10
R6229:Dnah3	UTSW	7	119,965,488 (GRCm38)	missense	probably benign	0.11
R6237:Dnah3	UTSW	7	120,009,384 (GRCm38)	missense	probably damaging	1.00
R6333:Dnah3	UTSW	7	120,054,633 (GRCm38)	missense	probably damaging	1.00
R6408:Dnah3	UTSW	7	119,922,968 (GRCm38)	splice site	probably null
R6447:Dnah3	UTSW	7	119,923,054 (GRCm38)	missense	probably benign	0.12
R6606:Dnah3	UTSW	7	120,060,956 (GRCm38)	missense	probably benign	0.02
R6666:Dnah3	UTSW	7	120,070,949 (GRCm38)	missense	probably benign	0.16
R6733:Dnah3	UTSW	7	119,922,974 (GRCm38)	missense	probably benign	0.22
R6815:Dnah3	UTSW	7	119,971,727 (GRCm38)	missense	probably benign
R6882:Dnah3	UTSW	7	119,971,184 (GRCm38)	missense	possibly damaging	0.95
R6934:Dnah3	UTSW	7	120,054,601 (GRCm38)	critical splice donor site	probably null
R6966:Dnah3	UTSW	7	120,032,754 (GRCm38)	missense	probably damaging	1.00
R7025:Dnah3	UTSW	7	120,030,010 (GRCm38)	missense	possibly damaging	0.90
R7207:Dnah3	UTSW	7	119,971,089 (GRCm38)	missense	probably damaging	1.00
R7214:Dnah3	UTSW	7	119,922,742 (GRCm38)	missense	probably damaging	1.00
R7222:Dnah3	UTSW	7	120,071,523 (GRCm38)	missense	probably benign	0.00
R7235:Dnah3	UTSW	7	120,032,670 (GRCm38)	missense	probably damaging	1.00
R7241:Dnah3	UTSW	7	119,943,633 (GRCm38)	missense	probably benign	0.03
R7313:Dnah3	UTSW	7	119,981,344 (GRCm38)	missense	probably benign	0.39
R7342:Dnah3	UTSW	7	120,029,985 (GRCm38)	missense	probably damaging	1.00
R7368:Dnah3	UTSW	7	120,029,016 (GRCm38)	missense	probably benign
R7375:Dnah3	UTSW	7	119,951,677 (GRCm38)	missense	probably damaging	1.00
R7395:Dnah3	UTSW	7	120,060,960 (GRCm38)	missense	probably benign	0.00
R7395:Dnah3	UTSW	7	119,966,251 (GRCm38)	missense
R7431:Dnah3	UTSW	7	120,051,744 (GRCm38)	missense	probably damaging	1.00
R7499:Dnah3	UTSW	7	120,060,912 (GRCm38)	missense	probably damaging	0.99
R7515:Dnah3	UTSW	7	120,073,592 (GRCm38)	missense	probably benign	0.21
R7564:Dnah3	UTSW	7	119,971,594 (GRCm38)	missense	probably benign
R7618:Dnah3	UTSW	7	119,978,378 (GRCm38)	missense	probably damaging	0.97
R7697:Dnah3	UTSW	7	119,967,434 (GRCm38)	missense
R7728:Dnah3	UTSW	7	119,938,828 (GRCm38)	missense	probably damaging	1.00
R7757:Dnah3	UTSW	7	119,971,215 (GRCm38)	splice site	probably null
R7757:Dnah3	UTSW	7	120,071,570 (GRCm38)	missense	probably benign
R7774:Dnah3	UTSW	7	119,951,752 (GRCm38)	nonsense	probably null
R7804:Dnah3	UTSW	7	120,011,012 (GRCm38)	missense	probably damaging	1.00
R7804:Dnah3	UTSW	7	119,952,618 (GRCm38)	missense	probably damaging	1.00
R7857:Dnah3	UTSW	7	119,951,704 (GRCm38)	missense	probably damaging	1.00
R7871:Dnah3	UTSW	7	119,967,552 (GRCm38)	missense
R7903:Dnah3	UTSW	7	120,042,128 (GRCm38)	missense	probably damaging	1.00
R7927:Dnah3	UTSW	7	119,951,271 (GRCm38)	missense	probably damaging	0.97
R7989:Dnah3	UTSW	7	120,077,789 (GRCm38)	missense	probably benign
R8142:Dnah3	UTSW	7	120,060,966 (GRCm38)	missense	probably benign	0.00
R8164:Dnah3	UTSW	7	119,967,614 (GRCm38)	missense	probably damaging	1.00
R8237:Dnah3	UTSW	7	119,926,413 (GRCm38)	missense	probably benign	0.01
R8313:Dnah3	UTSW	7	119,951,152 (GRCm38)	missense	probably benign	0.38
R8338:Dnah3	UTSW	7	120,071,881 (GRCm38)	missense	probably benign	0.01
R8355:Dnah3	UTSW	7	119,952,208 (GRCm38)	missense	probably damaging	1.00
R8408:Dnah3	UTSW	7	119,952,505 (GRCm38)	missense	probably damaging	1.00
R8411:Dnah3	UTSW	7	120,011,030 (GRCm38)	missense	probably damaging	1.00
R8455:Dnah3	UTSW	7	119,952,208 (GRCm38)	missense	probably damaging	1.00
R8483:Dnah3	UTSW	7	119,937,030 (GRCm38)	missense	probably benign	0.00
R8531:Dnah3	UTSW	7	119,951,368 (GRCm38)	missense	probably damaging	1.00
R8885:Dnah3	UTSW	7	119,962,152 (GRCm38)	missense
R8912:Dnah3	UTSW	7	120,090,646 (GRCm38)	missense	probably benign	0.06
R8966:Dnah3	UTSW	7	119,950,658 (GRCm38)	nonsense	probably null
R8982:Dnah3	UTSW	7	119,937,071 (GRCm38)	missense	probably damaging	1.00
R9043:Dnah3	UTSW	7	119,952,049 (GRCm38)	missense	probably benign
R9053:Dnah3	UTSW	7	120,019,764 (GRCm38)	missense	possibly damaging	0.67
R9059:Dnah3	UTSW	7	120,085,145 (GRCm38)	missense	probably benign	0.01
R9182:Dnah3	UTSW	7	120,085,128 (GRCm38)	missense	probably damaging	0.98
R9365:Dnah3	UTSW	7	119,967,636 (GRCm38)	missense
R9383:Dnah3	UTSW	7	120,047,596 (GRCm38)	missense	probably benign	0.23
R9430:Dnah3	UTSW	7	120,028,982 (GRCm38)	missense	probably damaging	1.00
R9449:Dnah3	UTSW	7	119,952,250 (GRCm38)	missense	probably benign	0.12
R9462:Dnah3	UTSW	7	119,952,300 (GRCm38)	missense	probably benign	0.05
R9505:Dnah3	UTSW	7	120,045,689 (GRCm38)	missense	probably damaging	1.00
R9559:Dnah3	UTSW	7	120,051,728 (GRCm38)	missense	probably benign	0.07
R9562:Dnah3	UTSW	7	120,010,891 (GRCm38)	missense	probably benign	0.05
R9565:Dnah3	UTSW	7	120,010,891 (GRCm38)	missense	probably benign	0.05
R9609:Dnah3	UTSW	7	120,071,013 (GRCm38)	missense	probably damaging	0.98
R9622:Dnah3	UTSW	7	119,962,133 (GRCm38)	missense
R9633:Dnah3	UTSW	7	119,950,993 (GRCm38)	missense	probably benign
R9654:Dnah3	UTSW	7	120,042,173 (GRCm38)	nonsense	probably null
R9665:Dnah3	UTSW	7	120,045,758 (GRCm38)	missense	probably benign	0.01
R9681:Dnah3	UTSW	7	120,078,388 (GRCm38)	missense	probably benign	0.04
R9717:Dnah3	UTSW	7	119,975,076 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah3	UTSW	7	120,010,873 (GRCm38)	missense	probably null	1.00
Z1088:Dnah3	UTSW	7	120,086,297 (GRCm38)	missense	probably benign	0.00
Z1176:Dnah3	UTSW	7	119,967,803 (GRCm38)	missense
Z1177:Dnah3	UTSW	7	120,007,862 (GRCm38)	missense	probably benign
Z1177:Dnah3	UTSW	7	119,967,901 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- GACCCTAATGACTCCAGAGGAC -3'
(R):5'- GTCCACGTTCATGAACTCCTATG -3'

Sequencing Primer
(F):5'- CAGACAGAATTTGACTGCTTCTCAC -3'
(R):5'- AGTGGCCACCAAGAGTA -3'

Posted On

2014-08-25