Incidental Mutation 'R2004:Sphkap'
| ID |
223293 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sphkap
|
| Ensembl Gene |
ENSMUSG00000026163 |
| Gene Name |
SPHK1 interactor, AKAP domain containing |
| Synonyms |
4930544G21Rik, A930009L15Rik, SKIP |
| MMRRC Submission |
040013-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.093)
|
| Stock # |
R2004 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
83254139-83408200 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 83277911 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Valine
at position 706
(M706V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124872
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159078]
[ENSMUST00000160953]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000053075
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159078
AA Change: M419V
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000124384
Gene: ENSMUSG00000026163
AA Change: M419V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
303 |
314 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
382 |
462 |
5e-3 |
SMART |
|
low complexity region
|
809 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1221 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1254 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1281 |
1398 |
7.5e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160953
AA Change: M706V
PolyPhen 2
Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000124872
Gene: ENSMUSG00000026163
AA Change: M706V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
590 |
601 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
669 |
749 |
6e-3 |
SMART |
|
low complexity region
|
1096 |
1106 |
N/A |
INTRINSIC |
|
low complexity region
|
1141 |
1152 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1508 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1540 |
1655 |
6.4e-12 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 94.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aass |
A |
T |
6: 23,092,562 (GRCm38) |
Y146* |
probably null |
Het |
| Adcy2 |
A |
G |
13: 68,796,603 (GRCm38) |
L220P |
probably damaging |
Het |
| Agl |
T |
C |
3: 116,781,265 (GRCm38) |
Y660C |
probably damaging |
Het |
| Ak1 |
A |
G |
2: 32,629,610 (GRCm38) |
T17A |
probably benign |
Het |
| Amph |
G |
A |
13: 19,142,028 (GRCm38) |
V643M |
probably damaging |
Het |
| Ankrd11 |
A |
T |
8: 122,902,422 (GRCm38) |
|
probably null |
Het |
| Ap5b1 |
T |
C |
19: 5,570,474 (GRCm38) |
S641P |
possibly damaging |
Het |
| Apoc4 |
A |
G |
7: 19,681,379 (GRCm38) |
M1T |
probably null |
Het |
| Arhgap5 |
T |
C |
12: 52,518,034 (GRCm38) |
V596A |
probably benign |
Het |
| Ascc3 |
A |
G |
10: 50,617,742 (GRCm38) |
E91G |
probably damaging |
Het |
| Bach2 |
T |
A |
4: 32,580,055 (GRCm38) |
V637E |
probably benign |
Het |
| Bicd2 |
T |
G |
13: 49,379,405 (GRCm38) |
L489R |
possibly damaging |
Het |
| Bltp1 |
C |
T |
3: 36,895,378 (GRCm38) |
T2I |
possibly damaging |
Het |
| Boc |
A |
T |
16: 44,501,644 (GRCm38) |
|
probably null |
Het |
| Cbln2 |
T |
A |
18: 86,716,666 (GRCm38) |
V188D |
probably damaging |
Het |
| Ccl11 |
A |
C |
11: 82,062,297 (GRCm38) |
T94P |
probably damaging |
Het |
| Cd109 |
A |
T |
9: 78,703,762 (GRCm38) |
H1220L |
probably benign |
Het |
| Cd226 |
A |
G |
18: 89,247,311 (GRCm38) |
I125V |
probably benign |
Het |
| Cep135 |
T |
A |
5: 76,632,329 (GRCm38) |
|
probably null |
Het |
| Cgnl1 |
T |
G |
9: 71,630,539 (GRCm38) |
E1233A |
probably damaging |
Het |
| Ckap5 |
T |
A |
2: 91,607,546 (GRCm38) |
D1597E |
possibly damaging |
Het |
| Clptm1 |
A |
G |
7: 19,646,837 (GRCm38) |
I63T |
possibly damaging |
Het |
| Cpsf7 |
C |
T |
19: 10,540,709 (GRCm38) |
P428S |
probably damaging |
Het |
| Cuedc1 |
C |
T |
11: 88,177,390 (GRCm38) |
P155S |
probably damaging |
Het |
| Dgkb |
T |
C |
12: 38,084,229 (GRCm38) |
Y45H |
probably damaging |
Het |
| Dglucy |
T |
C |
12: 100,856,922 (GRCm38) |
F459L |
probably damaging |
Het |
| Dmp1 |
T |
A |
5: 104,211,924 (GRCm38) |
D155E |
possibly damaging |
Het |
| Dnah1 |
T |
A |
14: 31,301,856 (GRCm38) |
I960F |
possibly damaging |
Het |
| Drosha |
G |
T |
15: 12,915,381 (GRCm38) |
M795I |
probably damaging |
Het |
| Dsg1b |
A |
G |
18: 20,396,475 (GRCm38) |
T326A |
probably damaging |
Het |
| Dusp16 |
T |
G |
6: 134,718,839 (GRCm38) |
N343T |
probably benign |
Het |
| Faim2 |
T |
C |
15: 99,500,246 (GRCm38) |
S274G |
possibly damaging |
Het |
| Fhip2a |
G |
T |
19: 57,381,892 (GRCm38) |
V523L |
probably benign |
Het |
| Fndc1 |
T |
C |
17: 7,804,929 (GRCm38) |
R65G |
probably damaging |
Het |
| Fnip2 |
A |
T |
3: 79,512,325 (GRCm38) |
|
probably benign |
Het |
| Grm3 |
T |
C |
5: 9,589,793 (GRCm38) |
Y84C |
possibly damaging |
Het |
| Herc2 |
T |
C |
7: 56,137,859 (GRCm38) |
F1755L |
probably damaging |
Het |
| Hivep1 |
C |
T |
13: 42,160,149 (GRCm38) |
T1955I |
possibly damaging |
Het |
| Ift20 |
T |
C |
11: 78,540,971 (GRCm38) |
I97T |
probably damaging |
Het |
| Il1f5 |
T |
C |
2: 24,281,364 (GRCm38) |
C155R |
probably damaging |
Het |
| Lca5l |
T |
A |
16: 96,162,649 (GRCm38) |
K358N |
probably damaging |
Het |
| Lca5l |
T |
C |
16: 96,176,018 (GRCm38) |
N196S |
possibly damaging |
Het |
| Maf1 |
G |
A |
15: 76,353,363 (GRCm38) |
D175N |
probably damaging |
Het |
| Mical3 |
T |
C |
6: 120,951,322 (GRCm38) |
K996E |
probably damaging |
Het |
| Midn |
A |
G |
10: 80,155,149 (GRCm38) |
N331S |
probably benign |
Het |
| Mki67 |
T |
A |
7: 135,698,509 (GRCm38) |
K1599* |
probably null |
Het |
| Mlx |
A |
G |
11: 101,088,979 (GRCm38) |
Q162R |
possibly damaging |
Het |
| Nalf1 |
A |
G |
8: 9,770,607 (GRCm38) |
S138P |
probably benign |
Het |
| Ngp |
T |
C |
9: 110,420,861 (GRCm38) |
C76R |
probably damaging |
Het |
| Nin |
C |
T |
12: 70,025,477 (GRCm38) |
G1210D |
probably benign |
Het |
| Nlgn1 |
A |
G |
3: 25,433,870 (GRCm38) |
I738T |
probably benign |
Het |
| Nop53 |
A |
C |
7: 15,938,228 (GRCm38) |
F465C |
probably damaging |
Het |
| Npas3 |
A |
G |
12: 54,067,897 (GRCm38) |
D503G |
possibly damaging |
Het |
| Npbwr1 |
T |
A |
1: 5,916,351 (GRCm38) |
S315C |
probably damaging |
Het |
| Nup42 |
G |
T |
5: 24,181,991 (GRCm38) |
G260* |
probably null |
Het |
| Ogdh |
G |
C |
11: 6,334,626 (GRCm38) |
R200P |
possibly damaging |
Het |
| Or4b13 |
T |
A |
2: 90,252,692 (GRCm38) |
I99L |
probably benign |
Het |
| Or52n20 |
A |
G |
7: 104,671,601 (GRCm38) |
T300A |
possibly damaging |
Het |
| Or5m13b |
T |
G |
2: 85,923,595 (GRCm38) |
|
probably null |
Het |
| Or6ae1 |
C |
T |
7: 140,162,816 (GRCm38) |
V45I |
probably damaging |
Het |
| Or7g16 |
G |
A |
9: 18,815,505 (GRCm38) |
S263L |
probably benign |
Het |
| Or7g33 |
A |
T |
9: 19,537,392 (GRCm38) |
C179* |
probably null |
Het |
| Ovgp1 |
T |
A |
3: 105,986,993 (GRCm38) |
|
probably benign |
Het |
| Papln |
T |
A |
12: 83,773,218 (GRCm38) |
C150S |
probably damaging |
Het |
| Pde1c |
A |
T |
6: 56,159,011 (GRCm38) |
L316Q |
probably damaging |
Het |
| Pdlim2 |
C |
T |
14: 70,164,779 (GRCm38) |
R296H |
probably damaging |
Het |
| Piezo2 |
G |
T |
18: 63,144,926 (GRCm38) |
D302E |
probably damaging |
Het |
| Pirb |
A |
T |
7: 3,717,638 (GRCm38) |
L287Q |
probably benign |
Het |
| Plin1 |
A |
G |
7: 79,725,630 (GRCm38) |
|
probably benign |
Het |
| Plxnc1 |
A |
G |
10: 94,852,622 (GRCm38) |
I698T |
probably damaging |
Het |
| Ppp1r12c |
G |
T |
7: 4,482,975 (GRCm38) |
C572* |
probably null |
Het |
| Ptgis |
T |
C |
2: 167,214,849 (GRCm38) |
M273V |
possibly damaging |
Het |
| Samd14 |
C |
A |
11: 95,023,284 (GRCm38) |
T283K |
probably damaging |
Het |
| Scnn1g |
A |
T |
7: 121,738,188 (GRCm38) |
K91* |
probably null |
Het |
| Slc24a4 |
A |
G |
12: 102,213,907 (GRCm38) |
Q95R |
probably damaging |
Het |
| Slfn9 |
T |
G |
11: 82,988,201 (GRCm38) |
D34A |
probably benign |
Het |
| Smarca4 |
A |
T |
9: 21,677,480 (GRCm38) |
I1193F |
probably damaging |
Het |
| Spata31e5 |
A |
G |
1: 28,777,179 (GRCm38) |
W591R |
probably damaging |
Het |
| Stard9 |
C |
A |
2: 120,673,636 (GRCm38) |
S221R |
probably damaging |
Het |
| Stxbp1 |
T |
C |
2: 32,798,189 (GRCm38) |
D488G |
probably damaging |
Het |
| Sugp2 |
C |
T |
8: 70,242,656 (GRCm38) |
|
probably null |
Het |
| Tekt5 |
T |
C |
16: 10,395,206 (GRCm38) |
I72V |
probably benign |
Het |
| Themis |
T |
A |
10: 28,782,724 (GRCm38) |
N582K |
probably benign |
Het |
| Tmed11 |
C |
A |
5: 108,786,134 (GRCm38) |
M65I |
possibly damaging |
Het |
| Top3a |
G |
T |
11: 60,742,489 (GRCm38) |
P927Q |
probably damaging |
Het |
| Trpa1 |
A |
T |
1: 14,905,983 (GRCm38) |
N165K |
possibly damaging |
Het |
| Tsfm |
A |
G |
10: 127,030,794 (GRCm38) |
S2P |
probably damaging |
Het |
| Wdr47 |
C |
A |
3: 108,627,442 (GRCm38) |
S559* |
probably null |
Het |
| Wnt2b |
T |
C |
3: 104,953,015 (GRCm38) |
Y192C |
probably damaging |
Het |
| Zfp280b |
A |
G |
10: 76,038,536 (GRCm38) |
D83G |
probably benign |
Het |
| Zfp345 |
T |
C |
2: 150,472,118 (GRCm38) |
T500A |
possibly damaging |
Het |
| Zfp78 |
T |
A |
7: 6,379,075 (GRCm38) |
C343S |
probably damaging |
Het |
|
| Other mutations in Sphkap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00332:Sphkap
|
APN |
1 |
83,280,516 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00337:Sphkap
|
APN |
1 |
83,339,608 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00470:Sphkap
|
APN |
1 |
83,277,910 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
IGL00577:Sphkap
|
APN |
1 |
83,278,844 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00657:Sphkap
|
APN |
1 |
83,276,375 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01868:Sphkap
|
APN |
1 |
83,280,399 (GRCm38) |
splice site |
probably null |
|
|
IGL02101:Sphkap
|
APN |
1 |
83,290,987 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02471:Sphkap
|
APN |
1 |
83,276,176 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02943:Sphkap
|
APN |
1 |
83,276,831 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02945:Sphkap
|
APN |
1 |
83,276,831 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03008:Sphkap
|
APN |
1 |
83,276,831 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03031:Sphkap
|
APN |
1 |
83,276,831 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03059:Sphkap
|
APN |
1 |
83,257,242 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL03085:Sphkap
|
APN |
1 |
83,280,354 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL03355:Sphkap
|
APN |
1 |
83,280,503 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03356:Sphkap
|
APN |
1 |
83,276,831 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03368:Sphkap
|
APN |
1 |
83,275,676 (GRCm38) |
missense |
probably benign |
0.14 |
|
R0294:Sphkap
|
UTSW |
1 |
83,278,245 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R0308:Sphkap
|
UTSW |
1 |
83,276,969 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0478:Sphkap
|
UTSW |
1 |
83,278,711 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0606:Sphkap
|
UTSW |
1 |
83,280,424 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0678:Sphkap
|
UTSW |
1 |
83,278,628 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1216:Sphkap
|
UTSW |
1 |
83,290,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1253:Sphkap
|
UTSW |
1 |
83,278,898 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R1532:Sphkap
|
UTSW |
1 |
83,257,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1635:Sphkap
|
UTSW |
1 |
83,278,400 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1655:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1657:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1700:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1701:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1734:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1736:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1743:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1744:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1760:Sphkap
|
UTSW |
1 |
83,277,544 (GRCm38) |
missense |
probably benign |
0.29 |
|
R1893:Sphkap
|
UTSW |
1 |
83,278,966 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1937:Sphkap
|
UTSW |
1 |
83,267,441 (GRCm38) |
nonsense |
probably null |
|
|
R1986:Sphkap
|
UTSW |
1 |
83,277,922 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1993:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R1995:Sphkap
|
UTSW |
1 |
83,277,515 (GRCm38) |
nonsense |
probably null |
|
|
R2001:Sphkap
|
UTSW |
1 |
83,276,662 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2111:Sphkap
|
UTSW |
1 |
83,275,881 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2112:Sphkap
|
UTSW |
1 |
83,275,881 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2156:Sphkap
|
UTSW |
1 |
83,277,989 (GRCm38) |
missense |
probably benign |
0.03 |
|
R2182:Sphkap
|
UTSW |
1 |
83,276,684 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2271:Sphkap
|
UTSW |
1 |
83,257,221 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3712:Sphkap
|
UTSW |
1 |
83,277,112 (GRCm38) |
missense |
probably benign |
0.27 |
|
R3919:Sphkap
|
UTSW |
1 |
83,276,458 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3980:Sphkap
|
UTSW |
1 |
83,267,494 (GRCm38) |
splice site |
probably null |
|
|
R4130:Sphkap
|
UTSW |
1 |
83,277,898 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4539:Sphkap
|
UTSW |
1 |
83,277,793 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4602:Sphkap
|
UTSW |
1 |
83,279,061 (GRCm38) |
nonsense |
probably null |
|
|
R4735:Sphkap
|
UTSW |
1 |
83,279,117 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4793:Sphkap
|
UTSW |
1 |
83,278,084 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4849:Sphkap
|
UTSW |
1 |
83,277,384 (GRCm38) |
missense |
probably benign |
0.03 |
|
R4880:Sphkap
|
UTSW |
1 |
83,288,817 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5213:Sphkap
|
UTSW |
1 |
83,280,503 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5277:Sphkap
|
UTSW |
1 |
83,276,164 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5331:Sphkap
|
UTSW |
1 |
83,276,782 (GRCm38) |
missense |
probably benign |
0.08 |
|
R5632:Sphkap
|
UTSW |
1 |
83,278,285 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5647:Sphkap
|
UTSW |
1 |
83,407,999 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5751:Sphkap
|
UTSW |
1 |
83,275,897 (GRCm38) |
missense |
probably benign |
0.27 |
|
R5935:Sphkap
|
UTSW |
1 |
83,339,599 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5999:Sphkap
|
UTSW |
1 |
83,267,405 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6232:Sphkap
|
UTSW |
1 |
83,280,479 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6318:Sphkap
|
UTSW |
1 |
83,278,378 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6474:Sphkap
|
UTSW |
1 |
83,278,823 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6602:Sphkap
|
UTSW |
1 |
83,275,758 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R6674:Sphkap
|
UTSW |
1 |
83,277,834 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6716:Sphkap
|
UTSW |
1 |
83,362,228 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6803:Sphkap
|
UTSW |
1 |
83,280,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6880:Sphkap
|
UTSW |
1 |
83,257,257 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6941:Sphkap
|
UTSW |
1 |
83,408,090 (GRCm38) |
start gained |
probably benign |
|
|
R7170:Sphkap
|
UTSW |
1 |
83,265,985 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7263:Sphkap
|
UTSW |
1 |
83,276,678 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7422:Sphkap
|
UTSW |
1 |
83,263,826 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7640:Sphkap
|
UTSW |
1 |
83,278,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7722:Sphkap
|
UTSW |
1 |
83,278,921 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7810:Sphkap
|
UTSW |
1 |
83,276,300 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7887:Sphkap
|
UTSW |
1 |
83,277,412 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7974:Sphkap
|
UTSW |
1 |
83,278,962 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7990:Sphkap
|
UTSW |
1 |
83,267,345 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8096:Sphkap
|
UTSW |
1 |
83,277,558 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8110:Sphkap
|
UTSW |
1 |
83,278,771 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R8125:Sphkap
|
UTSW |
1 |
83,263,582 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8153:Sphkap
|
UTSW |
1 |
83,278,009 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R8245:Sphkap
|
UTSW |
1 |
83,278,771 (GRCm38) |
missense |
probably benign |
0.14 |
|
R8394:Sphkap
|
UTSW |
1 |
83,276,076 (GRCm38) |
missense |
probably benign |
0.08 |
|
R8443:Sphkap
|
UTSW |
1 |
83,278,232 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8508:Sphkap
|
UTSW |
1 |
83,276,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8531:Sphkap
|
UTSW |
1 |
83,277,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8673:Sphkap
|
UTSW |
1 |
83,275,840 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8674:Sphkap
|
UTSW |
1 |
83,277,844 (GRCm38) |
missense |
probably benign |
0.04 |
|
R8682:Sphkap
|
UTSW |
1 |
83,279,276 (GRCm38) |
missense |
probably benign |
0.21 |
|
R8837:Sphkap
|
UTSW |
1 |
83,275,663 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R8857:Sphkap
|
UTSW |
1 |
83,280,567 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8902:Sphkap
|
UTSW |
1 |
83,278,964 (GRCm38) |
missense |
probably benign |
0.21 |
|
R8916:Sphkap
|
UTSW |
1 |
83,277,387 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R8944:Sphkap
|
UTSW |
1 |
83,279,206 (GRCm38) |
missense |
probably benign |
0.39 |
|
R9154:Sphkap
|
UTSW |
1 |
83,257,261 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9579:Sphkap
|
UTSW |
1 |
83,277,574 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9616:Sphkap
|
UTSW |
1 |
83,277,268 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9781:Sphkap
|
UTSW |
1 |
83,278,051 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,278,604 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,276,608 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,280,442 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,276,033 (GRCm38) |
nonsense |
probably null |
|
|
Z1177:Sphkap
|
UTSW |
1 |
83,276,431 (GRCm38) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACCGTGTGCATTGCTAAGAGG -3'
(R):5'- CAAGGCCAGATGCTTACAGC -3'
Sequencing Primer
(F):5'- CATTGCTAAGAGGCTGGCTGC -3'
(R):5'- AGCTCTTGGAATCTGTGAACCAG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation