Incidental Mutation 'R2018:Myom2'
| ID |
223429 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| MMRRC Submission |
040027-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.148)
|
| Stock # |
R2018 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 15181151 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Phenylalanine
at position 1350
(L1350F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000033842
AA Change: L1350F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
AA Change: L1350F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140033
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 93.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 111 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610028H24Rik |
C |
A |
10: 76,293,899 (GRCm39) |
F252L |
possibly damaging |
Het |
| 4930447A16Rik |
T |
G |
15: 37,440,742 (GRCm39) |
|
probably benign |
Het |
| Abca14 |
A |
T |
7: 119,815,408 (GRCm39) |
M219L |
probably benign |
Het |
| Abi3bp |
A |
G |
16: 56,498,159 (GRCm39) |
T918A |
probably damaging |
Het |
| Acss3 |
C |
T |
10: 106,772,068 (GRCm39) |
S669N |
probably benign |
Het |
| Adamts16 |
G |
A |
13: 70,927,637 (GRCm39) |
|
probably benign |
Het |
| Adamtsl4 |
A |
G |
3: 95,588,412 (GRCm39) |
Y559H |
probably damaging |
Het |
| Adgrg5 |
T |
A |
8: 95,661,108 (GRCm39) |
M106K |
probably damaging |
Het |
| Akt1 |
T |
C |
12: 112,626,059 (GRCm39) |
N71S |
probably damaging |
Het |
| Amer2 |
A |
C |
14: 60,615,894 (GRCm39) |
K30Q |
probably damaging |
Het |
| Anapc5 |
T |
C |
5: 122,938,587 (GRCm39) |
K383E |
probably damaging |
Het |
| Ano1 |
A |
G |
7: 144,207,987 (GRCm39) |
L258P |
probably damaging |
Het |
| Arb2a |
A |
G |
13: 78,147,756 (GRCm39) |
T321A |
possibly damaging |
Het |
| Arhgef10l |
A |
G |
4: 140,271,695 (GRCm39) |
S560P |
probably damaging |
Het |
| Arhgef40 |
T |
A |
14: 52,241,162 (GRCm39) |
L1395Q |
probably damaging |
Het |
| Arid1a |
A |
T |
4: 133,409,145 (GRCm39) |
D1787E |
unknown |
Het |
| Ces2h |
T |
C |
8: 105,745,030 (GRCm39) |
L388P |
probably damaging |
Het |
| Cfap54 |
T |
A |
10: 92,852,466 (GRCm39) |
N880I |
probably benign |
Het |
| Cryz |
T |
C |
3: 154,327,320 (GRCm39) |
V116A |
probably damaging |
Het |
| Csrp1 |
G |
A |
1: 135,678,366 (GRCm39) |
A159T |
probably damaging |
Het |
| Cttnbp2 |
A |
G |
6: 18,434,517 (GRCm39) |
F447S |
probably damaging |
Het |
| Cyp4a12a |
A |
T |
4: 115,184,702 (GRCm39) |
I328F |
probably damaging |
Het |
| Cyth4 |
T |
G |
15: 78,492,371 (GRCm39) |
H133Q |
probably damaging |
Het |
| Ddah2 |
A |
G |
17: 35,279,402 (GRCm39) |
I88V |
possibly damaging |
Het |
| Dmbt1 |
T |
G |
7: 130,712,718 (GRCm39) |
I1563S |
possibly damaging |
Het |
| Dnajc22 |
T |
C |
15: 98,999,114 (GRCm39) |
S100P |
probably benign |
Het |
| Fancl |
T |
A |
11: 26,372,459 (GRCm39) |
D123E |
probably damaging |
Het |
| Fbxo30 |
A |
G |
10: 11,166,772 (GRCm39) |
Q498R |
probably damaging |
Het |
| Fgd4 |
T |
C |
16: 16,253,824 (GRCm39) |
H581R |
probably benign |
Het |
| Gm2663 |
T |
C |
6: 40,974,900 (GRCm39) |
Q57R |
probably benign |
Het |
| Gm7247 |
A |
T |
14: 51,602,804 (GRCm39) |
M47L |
possibly damaging |
Het |
| Gsdmc2 |
T |
A |
15: 63,699,975 (GRCm39) |
|
probably null |
Het |
| Hc |
A |
C |
2: 34,903,540 (GRCm39) |
F1038C |
probably damaging |
Het |
| Heatr1 |
C |
A |
13: 12,429,359 (GRCm39) |
Q890K |
possibly damaging |
Het |
| Hipk4 |
C |
A |
7: 27,228,429 (GRCm39) |
T293K |
probably damaging |
Het |
| Hp1bp3 |
C |
A |
4: 137,948,943 (GRCm39) |
A2E |
probably damaging |
Het |
| Il6 |
T |
C |
5: 30,219,945 (GRCm39) |
|
probably null |
Het |
| Itga6 |
A |
G |
2: 71,648,828 (GRCm39) |
D104G |
probably benign |
Het |
| Krt24 |
A |
G |
11: 99,173,277 (GRCm39) |
S293P |
probably damaging |
Het |
| Krt4 |
C |
T |
15: 101,829,086 (GRCm39) |
R309Q |
probably damaging |
Het |
| Krt40 |
A |
T |
11: 99,430,913 (GRCm39) |
W199R |
probably damaging |
Het |
| Lamc1 |
T |
C |
1: 153,118,378 (GRCm39) |
E931G |
probably benign |
Het |
| Lamp3 |
A |
T |
16: 19,519,961 (GRCm39) |
M74K |
probably benign |
Het |
| Lgalsl2 |
A |
G |
7: 5,362,573 (GRCm39) |
D68G |
probably benign |
Het |
| Magel2 |
G |
A |
7: 62,028,844 (GRCm39) |
V583I |
unknown |
Het |
| Marchf7 |
T |
A |
2: 60,059,384 (GRCm39) |
Y37* |
probably null |
Het |
| Mrpl36 |
A |
G |
13: 73,479,687 (GRCm39) |
K66E |
probably damaging |
Het |
| Mrps35 |
G |
T |
6: 146,962,982 (GRCm39) |
E229* |
probably null |
Het |
| Mtmr6 |
T |
C |
14: 60,536,441 (GRCm39) |
M557T |
probably benign |
Het |
| Myocd |
A |
T |
11: 65,077,854 (GRCm39) |
I647N |
probably damaging |
Het |
| Nhsl3 |
A |
G |
4: 129,116,148 (GRCm39) |
S884P |
probably damaging |
Het |
| Nosip |
T |
A |
7: 44,726,033 (GRCm39) |
S197T |
probably benign |
Het |
| Npat |
A |
G |
9: 53,473,791 (GRCm39) |
K528E |
probably benign |
Het |
| Nyap2 |
A |
G |
1: 81,169,587 (GRCm39) |
T115A |
probably benign |
Het |
| Obi1 |
T |
A |
14: 104,759,978 (GRCm39) |
K24M |
probably damaging |
Het |
| Or10al6 |
A |
G |
17: 38,083,467 (GRCm39) |
R317G |
probably benign |
Het |
| Or4a72 |
A |
G |
2: 89,405,737 (GRCm39) |
V111A |
probably damaging |
Het |
| Or4c109 |
G |
T |
2: 88,818,489 (GRCm39) |
P19Q |
probably benign |
Het |
| Or51b6 |
T |
A |
7: 103,556,249 (GRCm39) |
V201D |
possibly damaging |
Het |
| Or5m3 |
A |
T |
2: 85,838,567 (GRCm39) |
Y149F |
probably damaging |
Het |
| Or8g55 |
A |
G |
9: 39,785,354 (GRCm39) |
Q261R |
probably benign |
Het |
| Orc1 |
T |
C |
4: 108,447,897 (GRCm39) |
V48A |
possibly damaging |
Het |
| Pde6d |
T |
C |
1: 86,474,438 (GRCm39) |
E69G |
probably damaging |
Het |
| Pdgfrb |
A |
T |
18: 61,216,406 (GRCm39) |
D1088V |
possibly damaging |
Het |
| Peg12 |
A |
G |
7: 62,113,386 (GRCm39) |
V237A |
probably benign |
Het |
| Phf8-ps |
T |
C |
17: 33,285,941 (GRCm39) |
N287S |
probably benign |
Het |
| Piezo1 |
A |
G |
8: 123,209,451 (GRCm39) |
F2371L |
probably benign |
Het |
| Podn |
T |
A |
4: 107,880,570 (GRCm39) |
S27C |
probably damaging |
Het |
| Pom121l2 |
A |
G |
13: 22,166,904 (GRCm39) |
M392V |
possibly damaging |
Het |
| Ppm1b |
A |
G |
17: 85,301,630 (GRCm39) |
K170R |
probably damaging |
Het |
| Rab18 |
A |
T |
18: 6,770,113 (GRCm39) |
|
probably null |
Het |
| Raet1d |
G |
A |
10: 22,246,911 (GRCm39) |
A80T |
probably damaging |
Het |
| Rfx7 |
T |
A |
9: 72,524,967 (GRCm39) |
V719E |
probably benign |
Het |
| Ror1 |
C |
T |
4: 100,265,038 (GRCm39) |
Q171* |
probably null |
Het |
| Rufy4 |
G |
A |
1: 74,180,106 (GRCm39) |
V454M |
possibly damaging |
Het |
| Ryr2 |
C |
T |
13: 11,866,074 (GRCm39) |
G292D |
possibly damaging |
Het |
| Ryr3 |
G |
T |
2: 112,611,410 (GRCm39) |
N2257K |
probably benign |
Het |
| Saal1 |
A |
G |
7: 46,348,913 (GRCm39) |
F306S |
possibly damaging |
Het |
| Sap18 |
A |
G |
14: 58,036,021 (GRCm39) |
N69S |
probably damaging |
Het |
| Sar1b |
A |
T |
11: 51,670,514 (GRCm39) |
|
probably null |
Het |
| Serpina3n |
G |
T |
12: 104,375,473 (GRCm39) |
V182L |
probably damaging |
Het |
| Setd3 |
A |
T |
12: 108,084,513 (GRCm39) |
H279Q |
probably damaging |
Het |
| Slc18a2 |
C |
A |
19: 59,264,937 (GRCm39) |
A307E |
possibly damaging |
Het |
| Slc4a10 |
A |
T |
2: 62,064,725 (GRCm39) |
D193V |
probably damaging |
Het |
| Spire2 |
T |
C |
8: 124,059,657 (GRCm39) |
C52R |
probably damaging |
Het |
| Syne2 |
A |
T |
12: 76,121,353 (GRCm39) |
I5940F |
probably damaging |
Het |
| Sytl1 |
C |
T |
4: 132,983,471 (GRCm39) |
S355N |
probably damaging |
Het |
| Tarbp1 |
C |
T |
8: 127,154,853 (GRCm39) |
V1424I |
probably damaging |
Het |
| Tatdn3 |
A |
T |
1: 190,781,477 (GRCm39) |
|
probably null |
Het |
| Tbpl1 |
T |
A |
10: 22,583,576 (GRCm39) |
E131D |
probably damaging |
Het |
| Telo2 |
A |
T |
17: 25,324,382 (GRCm39) |
M501K |
probably damaging |
Het |
| Terb1 |
A |
G |
8: 105,179,331 (GRCm39) |
V619A |
probably benign |
Het |
| Tmem132e |
A |
G |
11: 82,335,989 (GRCm39) |
T1024A |
probably benign |
Het |
| Tmem30a |
T |
C |
9: 79,681,500 (GRCm39) |
D223G |
probably damaging |
Het |
| Tmprss11d |
A |
G |
5: 86,487,413 (GRCm39) |
V19A |
probably damaging |
Het |
| Tnks |
A |
T |
8: 35,318,260 (GRCm39) |
S872T |
probably damaging |
Het |
| Tnxb |
A |
G |
17: 34,890,724 (GRCm39) |
S356G |
probably benign |
Het |
| Tob2 |
T |
C |
15: 81,735,400 (GRCm39) |
K190E |
probably damaging |
Het |
| Togaram1 |
T |
C |
12: 65,049,433 (GRCm39) |
V1240A |
possibly damaging |
Het |
| Trim13 |
T |
A |
14: 61,842,335 (GRCm39) |
C117* |
probably null |
Het |
| Trpv4 |
G |
A |
5: 114,772,666 (GRCm39) |
R308C |
probably damaging |
Het |
| Ttn |
C |
G |
2: 76,585,676 (GRCm39) |
D21987H |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,656,418 (GRCm39) |
|
probably null |
Het |
| Upp1 |
A |
T |
11: 9,083,240 (GRCm39) |
M111L |
possibly damaging |
Het |
| Vmn1r206 |
A |
T |
13: 22,804,358 (GRCm39) |
V283E |
probably damaging |
Het |
| Vmn2r79 |
G |
T |
7: 86,651,634 (GRCm39) |
L344F |
probably benign |
Het |
| Vmn2r93 |
T |
G |
17: 18,546,324 (GRCm39) |
I732S |
probably damaging |
Het |
| Vmn2r96 |
G |
T |
17: 18,804,263 (GRCm39) |
M504I |
probably benign |
Het |
| Vps39 |
T |
C |
2: 120,173,708 (GRCm39) |
Y147C |
probably damaging |
Het |
| Zbtb20 |
T |
A |
16: 43,398,015 (GRCm39) |
C35S |
possibly damaging |
Het |
| Zfp871 |
A |
T |
17: 32,993,751 (GRCm39) |
C475S |
probably damaging |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0116:Myom2
|
UTSW |
8 |
15,167,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0463:Myom2
|
UTSW |
8 |
15,154,123 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0544:Myom2
|
UTSW |
8 |
15,119,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Myom2
|
UTSW |
8 |
15,115,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2155:Myom2
|
UTSW |
8 |
15,134,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6248:Myom2
|
UTSW |
8 |
15,148,472 (GRCm39) |
splice site |
probably null |
|
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8094:Myom2
|
UTSW |
8 |
15,119,418 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTGGAGTCCTTGATGTGACC -3'
(R):5'- TAGCTCTGAGTGCCATGCAG -3'
Sequencing Primer
(F):5'- GCAGAGTCAGCCATTCTTTG -3'
(R):5'- CCATGCAGGCTGAGTGG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation