Mutagenetix > Incidental Mutation

Incidental Mutation 'R2020:Akap9'

223802

Institutional Source

Beutler Lab

Gene Symbol

Akap9

Ensembl Gene

ENSMUSG00000040407

Gene Name

A kinase (PRKA) anchor protein (yotiao) 9

Synonyms

AKAP450, G1-448-15, 5730481H23Rik, mei2-5, repro12

MMRRC Submission

040029-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.327) question?

Stock #

R2020 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

3928054-4081310 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 3961967 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 890 (V890A)

Ref Sequence

ENSEMBL: ENSMUSP00000046129 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000044492] [ENSMUST00000143365]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000044492
AA Change: V890A

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000046129
Gene: ENSMUSG00000040407
AA Change: V890A

Domain	Start	End	E-Value	Type
low complexity region	9	18	N/A	INTRINSIC
low complexity region	33	44	N/A	INTRINSIC
low complexity region	98	115	N/A	INTRINSIC
Blast:HPT	126	197	6e-21	BLAST
low complexity region	237	249	N/A	INTRINSIC
low complexity region	297	315	N/A	INTRINSIC
coiled coil region	404	593	N/A	INTRINSIC
coiled coil region	622	756	N/A	INTRINSIC
coiled coil region	777	843	N/A	INTRINSIC
coiled coil region	888	958	N/A	INTRINSIC
low complexity region	982	997	N/A	INTRINSIC
coiled coil region	1037	1065	N/A	INTRINSIC
low complexity region	1233	1246	N/A	INTRINSIC
internal_repeat_2	1247	1312	7.75e-5	PROSPERO
internal_repeat_1	1377	1485	2.63e-5	PROSPERO
coiled coil region	1522	1589	N/A	INTRINSIC
coiled coil region	1789	2107	N/A	INTRINSIC
coiled coil region	2132	2318	N/A	INTRINSIC
internal_repeat_1	2322	2445	2.63e-5	PROSPERO
coiled coil region	2455	2494	N/A	INTRINSIC
low complexity region	2587	2598	N/A	INTRINSIC
low complexity region	2627	2640	N/A	INTRINSIC
internal_repeat_2	2934	2997	7.75e-5	PROSPERO
low complexity region	3000	3016	N/A	INTRINSIC
coiled coil region	3109	3307	N/A	INTRINSIC
coiled coil region	3455	3493	N/A	INTRINSIC
coiled coil region	3521	3556	N/A	INTRINSIC
Pfam:PACT_coil_coil	3576	3657	1.2e-27	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140977

Predicted Effect

probably benign
Transcript: ENSMUST00000143365

SMART Domains

Protein: ENSMUSP00000117209
Gene: ENSMUSG00000040407

Domain	Start	End	E-Value	Type
low complexity region	9	18	N/A	INTRINSIC
low complexity region	33	44	N/A	INTRINSIC
low complexity region	122	133	N/A	INTRINSIC
Blast:HPT	144	215	9e-22	BLAST
low complexity region	255	267	N/A	INTRINSIC
low complexity region	315	333	N/A	INTRINSIC
coiled coil region	422	571	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177448

Meta Mutation Damage Score

0.0970

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.8%
20x: 93.6%

Validation Efficiency

99% (87/88)

MGI Phenotype

PHENOTYPE: Mice homozygous for a chemically induced allele exhibit male infertily with abnormal spermatogenesis and Sertoli maturation. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 86 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1600012P17Rik	C	A	1: 158,968,912 (GRCm38)		noncoding transcript	Het
9530053A07Rik	T	C	7: 28,155,594 (GRCm38)	S1882P	probably benign	Het
Adam17	G	A	12: 21,349,875 (GRCm38)	R177C	probably damaging	Het
Ak7	G	A	12: 105,745,332 (GRCm38)		probably null	Het
Alg6	A	G	4: 99,738,132 (GRCm38)	N59S	probably damaging	Het
Alkbh5	G	T	11: 60,538,549 (GRCm38)	A43S	probably benign	Het
Anxa2	C	A	9: 69,483,817 (GRCm38)	D162E	probably damaging	Het
Arap1	A	G	7: 101,401,518 (GRCm38)	H1136R	probably benign	Het
Arhgap18	A	G	10: 26,854,904 (GRCm38)	R121G	probably benign	Het
Arhgef4	A	T	1: 34,723,810 (GRCm38)	T716S	unknown	Het
Atg2a	T	C	19: 6,250,269 (GRCm38)		probably null	Het
Ccdc27	T	C	4: 154,033,313 (GRCm38)	I480V	probably null	Het
Cdipt	T	C	7: 126,976,933 (GRCm38)	V20A	possibly damaging	Het
Cgrrf1	C	T	14: 46,830,445 (GRCm38)		probably benign	Het
Chd7	G	A	4: 8,855,226 (GRCm38)	V2152I	probably benign	Het
Chd8	T	A	14: 52,215,241 (GRCm38)	S1274C	probably damaging	Het
Chuk	A	T	19: 44,107,343 (GRCm38)	M17K	possibly damaging	Het
Col14a1	C	T	15: 55,446,181 (GRCm38)		probably benign	Het
Col20a1	G	A	2: 181,013,163 (GRCm38)		probably null	Het
Cped1	A	G	6: 22,143,964 (GRCm38)	I570V	probably benign	Het
Cul9	C	G	17: 46,522,175 (GRCm38)	A1326P	probably damaging	Het
Ddx27	A	C	2: 167,033,771 (GRCm38)	Q674P	probably damaging	Het
Dennd6a	T	A	14: 26,612,003 (GRCm38)	F131L	probably damaging	Het
Dhx38	G	A	8: 109,556,869 (GRCm38)		probably benign	Het
Dido1	G	T	2: 180,659,585 (GRCm38)	N2175K	unknown	Het
Dmxl1	T	A	18: 49,889,558 (GRCm38)	Y1654*	probably null	Het
Dock7	T	A	4: 98,959,101 (GRCm38)	H1658L	probably damaging	Het
Dync2h1	T	A	9: 7,122,772 (GRCm38)	E2061D	probably damaging	Het
Dync2h1	T	C	9: 7,162,925 (GRCm38)	I555V	probably benign	Het
Eif2ak2	T	C	17: 78,863,963 (GRCm38)	E337G	possibly damaging	Het
Fabp12	T	A	3: 10,250,149 (GRCm38)	D46V	probably benign	Het
Fech	C	T	18: 64,478,727 (GRCm38)	E79K	probably damaging	Het
Flnc	A	T	6: 29,444,363 (GRCm38)	I693F	probably damaging	Het
Foxp2	G	A	6: 15,324,644 (GRCm38)	C97Y	possibly damaging	Het
Grin2b	A	G	6: 135,733,896 (GRCm38)	M884T	probably benign	Het
Gtf2ird1	T	C	5: 134,417,093 (GRCm38)	D28G	probably damaging	Het
Gtf3c4	C	A	2: 28,833,894 (GRCm38)	G468W	possibly damaging	Het
Ift172	A	T	5: 31,267,241 (GRCm38)	L201*	probably null	Het
Il1rl2	C	A	1: 40,365,214 (GRCm38)	S498R	probably damaging	Het
Ildr1	C	T	16: 36,725,541 (GRCm38)	R489W	probably damaging	Het
Itga10	G	A	3: 96,652,490 (GRCm38)	G487D	probably damaging	Het
Klk8	A	G	7: 43,799,216 (GRCm38)	N128D	probably benign	Het
Lgr6	G	A	1: 135,075,275 (GRCm38)	T79M	probably damaging	Het
Med6	T	C	12: 81,573,877 (GRCm38)	T232A	probably benign	Het
Mgat4e	A	G	1: 134,541,322 (GRCm38)	L328P	probably damaging	Het
Mttp	A	G	3: 138,118,402 (GRCm38)	Y138H	probably damaging	Het
Ngef	T	C	1: 87,545,968 (GRCm38)	R31G	probably benign	Het
Nipsnap2	C	A	5: 129,753,223 (GRCm38)		probably null	Het
Nlgn2	G	T	11: 69,828,441 (GRCm38)	N194K	probably damaging	Het
Olfr1026	A	G	2: 85,923,743 (GRCm38)	I158M	probably benign	Het
Olfr1245	A	T	2: 89,574,961 (GRCm38)	M255K	possibly damaging	Het
Olfr1450	G	A	19: 12,954,332 (GRCm38)	V248I	possibly damaging	Het
Olfr357	G	A	2: 36,997,652 (GRCm38)	V281M	possibly damaging	Het
Olfr894	A	G	9: 38,219,432 (GRCm38)	Y203C	possibly damaging	Het
Pcca	T	A	14: 122,813,222 (GRCm38)	M101K	possibly damaging	Het
Plekha6	A	G	1: 133,284,970 (GRCm38)	T671A	possibly damaging	Het
Prex2	G	A	1: 11,162,312 (GRCm38)	V868M	probably damaging	Het
Prkcq	G	A	2: 11,279,521 (GRCm38)	V501I	probably benign	Het
Prom1	T	A	5: 44,011,253 (GRCm38)		probably benign	Het
Ptprd	A	G	4: 76,133,161 (GRCm38)	V41A	probably damaging	Het
Rab39	C	T	9: 53,686,398 (GRCm38)	G189E	possibly damaging	Het
Ret	T	C	6: 118,180,382 (GRCm38)	K236E	possibly damaging	Het
Rfx6	G	A	10: 51,720,057 (GRCm38)		probably null	Het
Rnf213	A	G	11: 119,461,918 (GRCm38)	T3916A	probably damaging	Het
Rpn1	A	G	6: 88,095,683 (GRCm38)	N336S	probably damaging	Het
Sag	G	A	1: 87,805,315 (GRCm38)	A2T	probably damaging	Het
Sco2	T	C	15: 89,371,860 (GRCm38)	Y197C	probably damaging	Het
Sec23b	T	C	2: 144,566,944 (GRCm38)	I183T	possibly damaging	Het
Sec24b	C	T	3: 129,987,728 (GRCm38)	V1166M	probably damaging	Het
Slc27a5	A	T	7: 12,993,412 (GRCm38)	F361Y	probably damaging	Het
Spaca9	A	G	2: 28,696,001 (GRCm38)	L17P	probably damaging	Het
Sqor	T	C	2: 122,804,107 (GRCm38)		probably null	Het
Stx18	A	G	5: 38,135,244 (GRCm38)	H230R	probably damaging	Het
Tas2r130	A	T	6: 131,630,769 (GRCm38)	I21N	probably damaging	Het
Tcaf3	A	G	6: 42,593,724 (GRCm38)	S365P	possibly damaging	Het
Tinagl1	G	A	4: 130,166,972 (GRCm38)	H351Y	probably damaging	Het
Tmc2	T	C	2: 130,232,385 (GRCm38)	Y333H	probably damaging	Het
Trp53bp2	A	T	1: 182,442,819 (GRCm38)	T395S	probably damaging	Het
Tsc22d1	T	C	14: 76,418,333 (GRCm38)	S751P	probably damaging	Het
Ttc30a1	A	G	2: 75,980,935 (GRCm38)	V268A	probably benign	Het
Ttn	A	G	2: 76,827,024 (GRCm38)		probably benign	Het
Ugdh	T	C	5: 65,416,925 (GRCm38)	Y425C	probably damaging	Het
Vmn1r115	G	A	7: 20,844,169 (GRCm38)	L273F	probably null	Het
Vmn2r109	A	T	17: 20,541,186 (GRCm38)	C636*	probably null	Het
Vmn2r59	A	C	7: 42,043,779 (GRCm38)	Y466D	probably damaging	Het
Zic5	C	T	14: 122,464,830 (GRCm38)	G163D	unknown	Het

Other mutations in Akap9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00478:Akap9	APN	5	4,046,639 (GRCm38)	missense	probably damaging	0.97
IGL00642:Akap9	APN	5	3,960,842 (GRCm38)	missense	probably damaging	0.99
IGL00786:Akap9	APN	5	4,070,522 (GRCm38)	missense	probably damaging	1.00
IGL00788:Akap9	APN	5	4,060,480 (GRCm38)	missense	probably damaging	1.00
IGL00969:Akap9	APN	5	4,001,550 (GRCm38)	missense	probably benign
IGL01014:Akap9	APN	5	3,968,683 (GRCm38)	missense	probably benign	0.41
IGL01302:Akap9	APN	5	3,970,711 (GRCm38)	missense	probably benign	0.27
IGL01610:Akap9	APN	5	4,032,839 (GRCm38)	missense	possibly damaging	0.95
IGL01620:Akap9	APN	5	3,960,218 (GRCm38)	missense	probably benign	0.11
IGL01862:Akap9	APN	5	4,065,856 (GRCm38)	missense	probably damaging	0.99
IGL01862:Akap9	APN	5	3,951,705 (GRCm38)	missense	probably damaging	0.99
IGL02151:Akap9	APN	5	4,032,728 (GRCm38)	nonsense	probably null
IGL02635:Akap9	APN	5	4,070,500 (GRCm38)	missense	possibly damaging	0.59
IGL02858:Akap9	APN	5	4,069,130 (GRCm38)	missense	possibly damaging	0.88
IGL02967:Akap9	APN	5	3,976,164 (GRCm38)	missense	probably benign	0.07
IGL03064:Akap9	APN	5	3,968,755 (GRCm38)	missense	probably damaging	1.00
IGL03289:Akap9	APN	5	4,077,261 (GRCm38)	missense	probably damaging	1.00
Andy	UTSW	5	3,961,764 (GRCm38)	nonsense	probably null
blimey	UTSW	5	4,070,397 (GRCm38)	nonsense	probably null
hoarder	UTSW	5	4,069,089 (GRCm38)	missense	probably benign	0.00
marinarum	UTSW	5	4,013,875 (GRCm38)	nonsense	probably null
miser	UTSW	5	4,046,064 (GRCm38)	missense	probably benign	0.13
naviculus	UTSW	5	3,960,865 (GRCm38)	missense	probably damaging	0.98
thrifty	UTSW	5	3,976,209 (GRCm38)	missense	probably damaging	0.99
wee_one	UTSW	5	4,043,925 (GRCm38)	missense	probably damaging	1.00
FR4449:Akap9	UTSW	5	3,981,214 (GRCm38)	unclassified	probably benign
PIT1430001:Akap9	UTSW	5	4,029,849 (GRCm38)	missense	probably damaging	1.00
PIT4366001:Akap9	UTSW	5	4,046,221 (GRCm38)	missense	probably benign	0.24
R0088:Akap9	UTSW	5	3,961,946 (GRCm38)	missense	probably benign	0.22
R0309:Akap9	UTSW	5	4,069,038 (GRCm38)	missense	probably benign	0.01
R0387:Akap9	UTSW	5	3,951,678 (GRCm38)	splice site	probably benign
R0440:Akap9	UTSW	5	4,064,569 (GRCm38)	missense	probably damaging	0.99
R0441:Akap9	UTSW	5	3,961,714 (GRCm38)	missense	probably benign	0.15
R0491:Akap9	UTSW	5	3,972,851 (GRCm38)	unclassified	probably benign
R0501:Akap9	UTSW	5	3,970,685 (GRCm38)	missense	probably damaging	1.00
R0507:Akap9	UTSW	5	4,069,043 (GRCm38)	missense	probably benign	0.41
R0544:Akap9	UTSW	5	4,069,185 (GRCm38)	missense	probably benign	0.22
R0581:Akap9	UTSW	5	4,050,620 (GRCm38)	missense	probably benign	0.03
R0611:Akap9	UTSW	5	3,954,870 (GRCm38)	missense	probably benign	0.00
R0620:Akap9	UTSW	5	4,064,136 (GRCm38)	missense	probably damaging	0.98
R0639:Akap9	UTSW	5	4,060,318 (GRCm38)	missense	probably damaging	1.00
R0932:Akap9	UTSW	5	4,046,492 (GRCm38)	missense	possibly damaging	0.77
R0944:Akap9	UTSW	5	4,064,742 (GRCm38)	splice site	probably null
R1101:Akap9	UTSW	5	4,046,205 (GRCm38)	missense	probably benign	0.00
R1159:Akap9	UTSW	5	3,960,865 (GRCm38)	missense	probably damaging	0.98
R1170:Akap9	UTSW	5	4,055,671 (GRCm38)	missense	probably benign
R1185:Akap9	UTSW	5	3,948,783 (GRCm38)	missense	probably benign	0.13
R1185:Akap9	UTSW	5	3,948,783 (GRCm38)	missense	probably benign	0.13
R1185:Akap9	UTSW	5	3,948,783 (GRCm38)	missense	probably benign	0.13
R1453:Akap9	UTSW	5	3,975,614 (GRCm38)	splice site	probably null
R1551:Akap9	UTSW	5	4,069,174 (GRCm38)	missense	probably benign	0.02
R1608:Akap9	UTSW	5	3,961,783 (GRCm38)	missense	probably damaging	1.00
R1652:Akap9	UTSW	5	4,077,210 (GRCm38)	missense	probably damaging	1.00
R1659:Akap9	UTSW	5	4,064,633 (GRCm38)	missense	probably damaging	1.00
R1713:Akap9	UTSW	5	4,039,345 (GRCm38)	critical splice donor site	probably null
R1719:Akap9	UTSW	5	3,957,645 (GRCm38)	nonsense	probably null
R1720:Akap9	UTSW	5	3,972,791 (GRCm38)	missense	possibly damaging	0.63
R1757:Akap9	UTSW	5	4,001,667 (GRCm38)	missense	probably benign	0.41
R1872:Akap9	UTSW	5	4,001,406 (GRCm38)	missense	probably damaging	1.00
R1876:Akap9	UTSW	5	3,961,809 (GRCm38)	missense	probably benign	0.28
R1881:Akap9	UTSW	5	4,050,173 (GRCm38)	missense	probably benign
R1950:Akap9	UTSW	5	3,960,677 (GRCm38)	missense	probably damaging	1.00
R1980:Akap9	UTSW	5	3,972,771 (GRCm38)	missense	probably damaging	0.99
R1993:Akap9	UTSW	5	4,038,520 (GRCm38)	splice site	probably null
R2008:Akap9	UTSW	5	3,960,131 (GRCm38)	missense	possibly damaging	0.47
R2051:Akap9	UTSW	5	3,975,685 (GRCm38)	nonsense	probably null
R2061:Akap9	UTSW	5	3,961,010 (GRCm38)	missense	probably damaging	1.00
R2109:Akap9	UTSW	5	4,044,847 (GRCm38)	missense	possibly damaging	0.47
R2135:Akap9	UTSW	5	4,064,509 (GRCm38)	missense	probably damaging	1.00
R2225:Akap9	UTSW	5	4,077,271 (GRCm38)	missense	probably damaging	0.96
R2232:Akap9	UTSW	5	4,046,603 (GRCm38)	missense	probably damaging	1.00
R2424:Akap9	UTSW	5	4,065,279 (GRCm38)	missense	probably damaging	0.97
R2483:Akap9	UTSW	5	3,976,235 (GRCm38)	missense	possibly damaging	0.65
R2879:Akap9	UTSW	5	3,976,353 (GRCm38)	intron	probably benign
R3622:Akap9	UTSW	5	3,976,235 (GRCm38)	missense	possibly damaging	0.65
R3623:Akap9	UTSW	5	3,976,235 (GRCm38)	missense	possibly damaging	0.65
R3624:Akap9	UTSW	5	3,976,235 (GRCm38)	missense	possibly damaging	0.65
R3722:Akap9	UTSW	5	4,070,351 (GRCm38)	missense	probably damaging	1.00
R3806:Akap9	UTSW	5	3,954,410 (GRCm38)	missense	probably benign	0.00
R3919:Akap9	UTSW	5	3,961,764 (GRCm38)	nonsense	probably null
R4023:Akap9	UTSW	5	3,992,077 (GRCm38)	missense	possibly damaging	0.66
R4093:Akap9	UTSW	5	4,043,996 (GRCm38)	missense	probably damaging	0.99
R4434:Akap9	UTSW	5	4,032,708 (GRCm38)	missense	probably damaging	0.99
R4529:Akap9	UTSW	5	4,043,948 (GRCm38)	missense	probably damaging	1.00
R4530:Akap9	UTSW	5	4,043,948 (GRCm38)	missense	probably damaging	1.00
R4532:Akap9	UTSW	5	4,043,948 (GRCm38)	missense	probably damaging	1.00
R4533:Akap9	UTSW	5	4,043,948 (GRCm38)	missense	probably damaging	1.00
R4585:Akap9	UTSW	5	3,976,151 (GRCm38)	missense	probably benign	0.00
R4586:Akap9	UTSW	5	3,976,151 (GRCm38)	missense	probably benign	0.00
R4655:Akap9	UTSW	5	4,046,403 (GRCm38)	missense	probably benign	0.14
R4676:Akap9	UTSW	5	4,064,515 (GRCm38)	nonsense	probably null
R4676:Akap9	UTSW	5	4,032,774 (GRCm38)	missense	probably damaging	1.00
R4724:Akap9	UTSW	5	4,055,339 (GRCm38)	missense	probably benign
R4731:Akap9	UTSW	5	3,962,266 (GRCm38)	missense	possibly damaging	0.54
R4732:Akap9	UTSW	5	4,013,901 (GRCm38)	missense	probably damaging	0.98
R4733:Akap9	UTSW	5	4,013,901 (GRCm38)	missense	probably damaging	0.98
R4743:Akap9	UTSW	5	3,961,013 (GRCm38)	missense	probably damaging	1.00
R4749:Akap9	UTSW	5	3,968,737 (GRCm38)	missense	probably benign	0.41
R4756:Akap9	UTSW	5	4,001,418 (GRCm38)	missense	probably damaging	0.99
R4757:Akap9	UTSW	5	4,008,382 (GRCm38)	missense	probably damaging	1.00
R4860:Akap9	UTSW	5	4,034,916 (GRCm38)	intron	probably benign
R4937:Akap9	UTSW	5	4,050,145 (GRCm38)	splice site	probably null
R4960:Akap9	UTSW	5	3,957,664 (GRCm38)	missense	probably benign	0.15
R4974:Akap9	UTSW	5	3,961,466 (GRCm38)	missense	possibly damaging	0.81
R5101:Akap9	UTSW	5	4,001,748 (GRCm38)	missense	probably damaging	0.96
R5160:Akap9	UTSW	5	4,030,007 (GRCm38)	missense	probably damaging	1.00
R5200:Akap9	UTSW	5	3,960,734 (GRCm38)	missense	probably benign	0.00
R5245:Akap9	UTSW	5	3,976,209 (GRCm38)	missense	probably damaging	0.99
R5293:Akap9	UTSW	5	3,948,687 (GRCm38)	missense	probably damaging	0.99
R5408:Akap9	UTSW	5	4,058,458 (GRCm38)	missense	possibly damaging	0.84
R5507:Akap9	UTSW	5	3,968,683 (GRCm38)	missense	probably benign	0.41
R5517:Akap9	UTSW	5	4,001,665 (GRCm38)	missense	possibly damaging	0.76
R5579:Akap9	UTSW	5	4,064,714 (GRCm38)	missense	possibly damaging	0.93
R5619:Akap9	UTSW	5	3,954,760 (GRCm38)	intron	probably benign
R5645:Akap9	UTSW	5	4,050,590 (GRCm38)	missense	probably benign	0.09
R5669:Akap9	UTSW	5	4,050,540 (GRCm38)	nonsense	probably null
R5686:Akap9	UTSW	5	3,971,926 (GRCm38)	missense	probably benign	0.00
R5697:Akap9	UTSW	5	3,960,170 (GRCm38)	missense	possibly damaging	0.92
R5821:Akap9	UTSW	5	4,046,064 (GRCm38)	missense	probably benign	0.13
R5875:Akap9	UTSW	5	4,077,285 (GRCm38)	missense	probably benign	0.01
R5897:Akap9	UTSW	5	4,077,904 (GRCm38)	missense	probably benign	0.23
R5999:Akap9	UTSW	5	4,043,925 (GRCm38)	missense	probably damaging	1.00
R6025:Akap9	UTSW	5	4,032,801 (GRCm38)	missense	probably damaging	1.00
R6078:Akap9	UTSW	5	4,067,924 (GRCm38)	critical splice donor site	probably null
R6138:Akap9	UTSW	5	4,067,924 (GRCm38)	critical splice donor site	probably null
R6225:Akap9	UTSW	5	3,962,105 (GRCm38)	missense	probably damaging	1.00
R6243:Akap9	UTSW	5	4,065,000 (GRCm38)	splice site	probably null
R6326:Akap9	UTSW	5	3,962,061 (GRCm38)	missense	probably damaging	1.00
R6564:Akap9	UTSW	5	4,028,491 (GRCm38)	missense	probably damaging	0.98
R6617:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R6625:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R6632:Akap9	UTSW	5	4,013,842 (GRCm38)	splice site	probably null
R6677:Akap9	UTSW	5	4,029,869 (GRCm38)	missense	probably benign	0.21
R6717:Akap9	UTSW	5	4,064,086 (GRCm38)	missense	probably damaging	1.00
R6893:Akap9	UTSW	5	3,961,709 (GRCm38)	missense	probably benign	0.32
R6915:Akap9	UTSW	5	3,960,551 (GRCm38)	missense	probably benign	0.03
R6938:Akap9	UTSW	5	4,046,628 (GRCm38)	missense	possibly damaging	0.91
R6972:Akap9	UTSW	5	4,046,699 (GRCm38)	missense	possibly damaging	0.62
R6973:Akap9	UTSW	5	4,046,699 (GRCm38)	missense	possibly damaging	0.62
R6993:Akap9	UTSW	5	4,065,866 (GRCm38)	missense	possibly damaging	0.65
R7032:Akap9	UTSW	5	3,954,896 (GRCm38)	missense	probably benign
R7164:Akap9	UTSW	5	4,060,364 (GRCm38)	missense	probably damaging	0.96
R7170:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7192:Akap9	UTSW	5	4,005,723 (GRCm38)	splice site	probably null
R7284:Akap9	UTSW	5	3,956,246 (GRCm38)	missense	probably damaging	1.00
R7299:Akap9	UTSW	5	4,032,696 (GRCm38)	missense	probably damaging	1.00
R7313:Akap9	UTSW	5	4,004,933 (GRCm38)	missense	probably damaging	1.00
R7326:Akap9	UTSW	5	4,045,930 (GRCm38)	missense	possibly damaging	0.47
R7343:Akap9	UTSW	5	4,046,364 (GRCm38)	missense	probably damaging	0.99
R7455:Akap9	UTSW	5	3,972,792 (GRCm38)	missense	probably benign	0.03
R7482:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7489:Akap9	UTSW	5	4,004,933 (GRCm38)	missense	probably damaging	1.00
R7525:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7528:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7576:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7577:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7578:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7610:Akap9	UTSW	5	3,957,677 (GRCm38)	missense	possibly damaging	0.95
R7658:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R7754:Akap9	UTSW	5	4,046,736 (GRCm38)	missense	probably benign	0.03
R7818:Akap9	UTSW	5	4,013,875 (GRCm38)	nonsense	probably null
R7979:Akap9	UTSW	5	4,050,381 (GRCm38)	missense	probably benign
R7991:Akap9	UTSW	5	4,064,949 (GRCm38)	splice site	probably null
R8036:Akap9	UTSW	5	4,070,397 (GRCm38)	nonsense	probably null
R8054:Akap9	UTSW	5	4,038,707 (GRCm38)	critical splice donor site	probably null
R8116:Akap9	UTSW	5	4,061,183 (GRCm38)	missense	probably benign	0.04
R8150:Akap9	UTSW	5	3,961,982 (GRCm38)	missense	probably damaging	1.00
R8234:Akap9	UTSW	5	4,044,845 (GRCm38)	missense	probably benign	0.18
R8348:Akap9	UTSW	5	3,948,897 (GRCm38)	critical splice donor site	probably null
R8365:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R8366:Akap9	UTSW	5	3,968,745 (GRCm38)	missense	probably benign	0.04
R8448:Akap9	UTSW	5	3,948,897 (GRCm38)	critical splice donor site	probably null
R8466:Akap9	UTSW	5	4,038,659 (GRCm38)	missense	probably damaging	1.00
R8772:Akap9	UTSW	5	4,046,255 (GRCm38)	missense	probably damaging	1.00
R8881:Akap9	UTSW	5	3,961,279 (GRCm38)	missense
R8937:Akap9	UTSW	5	4,044,048 (GRCm38)	missense	possibly damaging	0.78
R8956:Akap9	UTSW	5	3,948,805 (GRCm38)	missense	possibly damaging	0.79
R9000:Akap9	UTSW	5	4,055,650 (GRCm38)	missense	probably benign
R9049:Akap9	UTSW	5	4,064,597 (GRCm38)	missense
R9074:Akap9	UTSW	5	4,077,959 (GRCm38)	missense	probably benign	0.40
R9124:Akap9	UTSW	5	4,061,284 (GRCm38)	missense	probably damaging	0.99
R9129:Akap9	UTSW	5	4,069,089 (GRCm38)	missense	probably benign	0.00
R9371:Akap9	UTSW	5	3,961,852 (GRCm38)	missense	possibly damaging	0.83
R9424:Akap9	UTSW	5	3,962,224 (GRCm38)	nonsense	probably null
R9424:Akap9	UTSW	5	3,962,223 (GRCm38)	nonsense	probably null
R9509:Akap9	UTSW	5	4,046,349 (GRCm38)	missense	probably benign
R9515:Akap9	UTSW	5	4,055,709 (GRCm38)	missense	probably damaging	1.00
R9567:Akap9	UTSW	5	4,077,311 (GRCm38)	missense	possibly damaging	0.89
R9587:Akap9	UTSW	5	4,069,149 (GRCm38)	missense	probably damaging	1.00
R9619:Akap9	UTSW	5	4,044,833 (GRCm38)	missense	probably damaging	1.00
R9635:Akap9	UTSW	5	4,050,545 (GRCm38)	missense	probably benign	0.20
R9680:Akap9	UTSW	5	3,961,587 (GRCm38)	missense	probably benign	0.03
R9691:Akap9	UTSW	5	3,960,491 (GRCm38)	missense	probably damaging	1.00
R9726:Akap9	UTSW	5	4,003,757 (GRCm38)	missense	probably benign	0.39
U15987:Akap9	UTSW	5	4,067,924 (GRCm38)	critical splice donor site	probably null
X0026:Akap9	UTSW	5	4,014,039 (GRCm38)	missense	probably damaging	1.00
X0057:Akap9	UTSW	5	3,975,598 (GRCm38)	critical splice acceptor site	probably null
Z1176:Akap9	UTSW	5	3,962,251 (GRCm38)	missense	probably damaging	0.96
Z1177:Akap9	UTSW	5	4,046,189 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CAGAGGGAGTATACTTGTCTGCTC -3'
(R):5'- CACTAGGGTTAGCGAGGAGTTC -3'

Sequencing Primer
(F):5'- TCAAGATAAGAGATGATTTAGAGGCC -3'
(R):5'- AGCGAGGAGTTCAAGTTCTC -3'

Posted On

2014-08-25