Incidental Mutation 'R2022:Nlrp9c'
| ID |
224140 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp9c
|
| Ensembl Gene |
ENSMUSG00000040614 |
| Gene Name |
NLR family, pyrin domain containing 9C |
| Synonyms |
Nalp9c, Nalp-zeta |
| MMRRC Submission |
040031-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2022 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
26064116-26103125 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 26084221 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 453
(Y453N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083106
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041845]
[ENSMUST00000085944]
|
| AlphaFold |
Q66X01 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041845
AA Change: Y453N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000036041
Gene: ENSMUSG00000040614
AA Change: Y453N
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
7.64e-22 |
SMART |
|
Pfam:NACHT
|
143 |
310 |
5.2e-31 |
PFAM |
|
LRR
|
637 |
664 |
4.36e1 |
SMART |
|
Blast:LRR
|
666 |
691 |
3e-6 |
BLAST |
|
LRR
|
693 |
720 |
1.02e0 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
6.88e-4 |
SMART |
|
LRR
|
779 |
806 |
5.06e0 |
SMART |
|
LRR
|
807 |
834 |
1.22e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000085944
AA Change: Y453N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000083106
Gene: ENSMUSG00000040614
AA Change: Y453N
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
7.64e-22 |
SMART |
|
Pfam:NACHT
|
143 |
310 |
2.8e-31 |
PFAM |
|
LRR
|
631 |
658 |
7.49e0 |
SMART |
|
LRR
|
692 |
719 |
4.36e1 |
SMART |
|
Blast:LRR
|
721 |
746 |
8e-6 |
BLAST |
|
LRR
|
748 |
775 |
1.02e0 |
SMART |
|
LRR
|
777 |
804 |
3e0 |
SMART |
|
LRR
|
805 |
832 |
6.88e-4 |
SMART |
|
LRR
|
834 |
861 |
2.17e0 |
SMART |
|
LRR
|
862 |
889 |
2.12e-4 |
SMART |
|
LRR
|
919 |
946 |
1.22e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160514
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160948
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam34l |
A |
T |
8: 44,078,954 (GRCm39) |
C423* |
probably null |
Het |
| Akr1cl |
T |
A |
1: 65,053,857 (GRCm39) |
Y271F |
probably benign |
Het |
| Asnsd1 |
A |
G |
1: 53,386,386 (GRCm39) |
S414P |
possibly damaging |
Het |
| Atp12a |
T |
A |
14: 56,602,739 (GRCm39) |
M1K |
probably null |
Het |
| Atp4b |
A |
C |
8: 13,437,477 (GRCm39) |
N225K |
possibly damaging |
Het |
| Auh |
G |
A |
13: 52,989,532 (GRCm39) |
P308L |
probably benign |
Het |
| Cactin |
C |
T |
10: 81,158,727 (GRCm39) |
T231I |
possibly damaging |
Het |
| Casp8ap2 |
T |
C |
4: 32,644,560 (GRCm39) |
V1211A |
probably benign |
Het |
| Ccdc180 |
C |
A |
4: 45,944,418 (GRCm39) |
H1423N |
probably benign |
Het |
| Cfap251 |
G |
A |
5: 123,411,853 (GRCm39) |
G495D |
probably benign |
Het |
| Chd9 |
T |
C |
8: 91,761,682 (GRCm39) |
Y2256H |
probably benign |
Het |
| Chst8 |
A |
G |
7: 34,374,589 (GRCm39) |
Y417H |
possibly damaging |
Het |
| Clcn6 |
A |
G |
4: 148,095,109 (GRCm39) |
|
probably null |
Het |
| Clec5a |
A |
T |
6: 40,562,128 (GRCm39) |
V12E |
probably damaging |
Het |
| Crebbp |
C |
T |
16: 3,903,683 (GRCm39) |
R1852H |
probably damaging |
Het |
| Cyp2c40 |
T |
A |
19: 39,801,224 (GRCm39) |
|
probably benign |
Het |
| Dip2c |
T |
C |
13: 9,601,836 (GRCm39) |
L265P |
probably damaging |
Het |
| Dnah3 |
A |
G |
7: 119,550,465 (GRCm39) |
Y3274H |
probably damaging |
Het |
| Dnah6 |
T |
A |
6: 73,004,405 (GRCm39) |
T3853S |
probably benign |
Het |
| Dnttip2 |
T |
C |
3: 122,069,870 (GRCm39) |
S362P |
probably damaging |
Het |
| Dst |
G |
A |
1: 34,205,372 (GRCm39) |
V1025I |
possibly damaging |
Het |
| Dym |
T |
C |
18: 75,213,321 (GRCm39) |
V181A |
probably benign |
Het |
| Dynlt4 |
A |
G |
4: 116,985,504 (GRCm39) |
E109G |
possibly damaging |
Het |
| Elk3 |
T |
A |
10: 93,101,539 (GRCm39) |
I71F |
probably damaging |
Het |
| Epb41l4a |
C |
T |
18: 34,054,893 (GRCm39) |
S65N |
probably benign |
Het |
| Erap1 |
T |
A |
13: 74,814,627 (GRCm39) |
V451E |
probably benign |
Het |
| F830045P16Rik |
T |
A |
2: 129,314,585 (GRCm39) |
I231F |
probably damaging |
Het |
| Fahd1 |
T |
C |
17: 25,068,814 (GRCm39) |
I88V |
probably benign |
Het |
| Fam120b |
C |
T |
17: 15,644,638 (GRCm39) |
T744I |
possibly damaging |
Het |
| Fam83f |
T |
G |
15: 80,576,468 (GRCm39) |
V373G |
possibly damaging |
Het |
| Frem1 |
G |
T |
4: 82,831,795 (GRCm39) |
T1988K |
probably benign |
Het |
| Gdap1l1 |
A |
T |
2: 163,289,517 (GRCm39) |
T161S |
probably benign |
Het |
| Gm6309 |
C |
T |
5: 146,105,121 (GRCm39) |
G264D |
probably benign |
Het |
| Hsd11b1 |
T |
C |
1: 192,922,686 (GRCm39) |
T124A |
probably benign |
Het |
| Ino80b |
A |
G |
6: 83,101,353 (GRCm39) |
M119T |
probably damaging |
Het |
| Kif3a |
G |
A |
11: 53,461,408 (GRCm39) |
V17M |
probably damaging |
Het |
| Krt40 |
T |
A |
11: 99,430,818 (GRCm39) |
E285D |
probably damaging |
Het |
| Lair1 |
C |
G |
7: 4,066,063 (GRCm39) |
|
probably null |
Het |
| Lvrn |
A |
G |
18: 46,999,503 (GRCm39) |
T290A |
possibly damaging |
Het |
| Macf1 |
G |
T |
4: 123,366,523 (GRCm39) |
A2746E |
probably damaging |
Het |
| Matn4 |
A |
G |
2: 164,242,573 (GRCm39) |
V175A |
probably damaging |
Het |
| Mok |
A |
T |
12: 110,778,257 (GRCm39) |
D216E |
probably benign |
Het |
| Muc15 |
A |
T |
2: 110,561,821 (GRCm39) |
T86S |
probably benign |
Het |
| Myo16 |
A |
G |
8: 10,322,633 (GRCm39) |
K21R |
probably benign |
Het |
| Ncl |
A |
G |
1: 86,284,677 (GRCm39) |
|
probably null |
Het |
| Nfrkb |
C |
T |
9: 31,322,546 (GRCm39) |
T872I |
probably benign |
Het |
| Nhlrc2 |
A |
T |
19: 56,585,710 (GRCm39) |
E648D |
probably benign |
Het |
| Notch4 |
T |
C |
17: 34,806,502 (GRCm39) |
L1813P |
probably damaging |
Het |
| Nrg3 |
T |
A |
14: 38,098,309 (GRCm39) |
D515V |
probably damaging |
Het |
| Nsd1 |
T |
C |
13: 55,361,092 (GRCm39) |
V20A |
probably damaging |
Het |
| Opn4 |
T |
A |
14: 34,319,028 (GRCm39) |
T186S |
probably benign |
Het |
| Or9k2 |
T |
C |
10: 129,999,049 (GRCm39) |
M49V |
probably benign |
Het |
| Pcdh15 |
T |
G |
10: 74,467,025 (GRCm39) |
S1684A |
possibly damaging |
Het |
| Phf11a |
T |
A |
14: 59,532,363 (GRCm39) |
E24V |
possibly damaging |
Het |
| Pigg |
A |
T |
5: 108,460,788 (GRCm39) |
|
probably benign |
Het |
| Plscr2 |
A |
G |
9: 92,177,647 (GRCm39) |
D136G |
probably damaging |
Het |
| Ppp3r2 |
T |
C |
4: 49,681,723 (GRCm39) |
I76V |
probably benign |
Het |
| Prdm6 |
A |
G |
18: 53,598,031 (GRCm39) |
|
probably benign |
Het |
| Prex1 |
A |
G |
2: 166,417,534 (GRCm39) |
W1188R |
possibly damaging |
Het |
| Prmt2 |
T |
A |
10: 76,061,292 (GRCm39) |
R65* |
probably null |
Het |
| Prom1 |
G |
T |
5: 44,187,068 (GRCm39) |
D396E |
probably benign |
Het |
| Ptcd3 |
C |
T |
6: 71,862,537 (GRCm39) |
C466Y |
probably damaging |
Het |
| Ptk2 |
A |
G |
15: 73,114,255 (GRCm39) |
V701A |
possibly damaging |
Het |
| Rab36 |
T |
C |
10: 74,888,306 (GRCm39) |
I250T |
probably benign |
Het |
| Rsf1 |
G |
A |
7: 97,229,117 (GRCm39) |
|
probably benign |
Het |
| Scn11a |
G |
T |
9: 119,640,274 (GRCm39) |
A207E |
possibly damaging |
Het |
| Serpinb3d |
A |
G |
1: 107,006,182 (GRCm39) |
V302A |
probably benign |
Het |
| Slc22a16 |
T |
C |
10: 40,467,873 (GRCm39) |
Y469H |
probably damaging |
Het |
| Smo |
A |
G |
6: 29,754,715 (GRCm39) |
N262D |
possibly damaging |
Het |
| Spata31e5 |
A |
T |
1: 28,817,234 (GRCm39) |
V266D |
probably damaging |
Het |
| Sptan1 |
C |
T |
2: 29,897,573 (GRCm39) |
A1212V |
probably damaging |
Het |
| Ssr1 |
C |
T |
13: 38,173,525 (GRCm39) |
A79T |
probably damaging |
Het |
| Tiam1 |
T |
A |
16: 89,674,075 (GRCm39) |
T479S |
probably benign |
Het |
| Tm9sf3 |
A |
G |
19: 41,227,231 (GRCm39) |
F280S |
probably damaging |
Het |
| Tmem72 |
T |
C |
6: 116,673,800 (GRCm39) |
H106R |
probably damaging |
Het |
| Tnr |
A |
G |
1: 159,679,592 (GRCm39) |
I189V |
probably benign |
Het |
| Tpbpa |
T |
A |
13: 61,088,036 (GRCm39) |
N50I |
probably benign |
Het |
| Tshz1 |
T |
A |
18: 84,031,987 (GRCm39) |
Y807F |
probably damaging |
Het |
| Tspo2 |
C |
T |
17: 48,755,750 (GRCm39) |
A131T |
possibly damaging |
Het |
| Usp16 |
T |
C |
16: 87,270,014 (GRCm39) |
L322P |
probably damaging |
Het |
| Vmn1r185 |
A |
G |
7: 26,310,935 (GRCm39) |
V190A |
possibly damaging |
Het |
| Vmn1r34 |
T |
C |
6: 66,614,385 (GRCm39) |
K118E |
possibly damaging |
Het |
| Vmn1r68 |
A |
G |
7: 10,261,918 (GRCm39) |
L60P |
probably damaging |
Het |
| Vmn2r-ps158 |
A |
G |
7: 42,673,454 (GRCm39) |
N171D |
probably benign |
Het |
| Vps51 |
T |
C |
19: 6,121,612 (GRCm39) |
E162G |
probably benign |
Het |
| Yy1 |
CGGG |
CGGGGGG |
12: 108,759,916 (GRCm39) |
|
probably benign |
Het |
| Zdhhc4 |
C |
T |
5: 143,307,538 (GRCm39) |
R161H |
probably damaging |
Het |
| Zfp456 |
A |
T |
13: 67,514,616 (GRCm39) |
C363* |
probably null |
Het |
| Zfp541 |
T |
A |
7: 15,816,110 (GRCm39) |
S866T |
probably damaging |
Het |
|
| Other mutations in Nlrp9c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00489:Nlrp9c
|
APN |
7 |
26,084,013 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00814:Nlrp9c
|
APN |
7 |
26,084,175 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL00919:Nlrp9c
|
APN |
7 |
26,093,481 (GRCm39) |
nonsense |
probably null |
|
|
IGL01762:Nlrp9c
|
APN |
7 |
26,084,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01928:Nlrp9c
|
APN |
7 |
26,074,847 (GRCm39) |
splice site |
probably benign |
|
|
IGL02008:Nlrp9c
|
APN |
7 |
26,084,576 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL02389:Nlrp9c
|
APN |
7 |
26,093,632 (GRCm39) |
missense |
probably benign |
|
|
IGL02535:Nlrp9c
|
APN |
7 |
26,071,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02685:Nlrp9c
|
APN |
7 |
26,084,982 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02904:Nlrp9c
|
APN |
7 |
26,074,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02935:Nlrp9c
|
APN |
7 |
26,084,701 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03006:Nlrp9c
|
APN |
7 |
26,071,507 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03140:Nlrp9c
|
APN |
7 |
26,079,914 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03201:Nlrp9c
|
APN |
7 |
26,084,533 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03243:Nlrp9c
|
APN |
7 |
26,064,457 (GRCm39) |
missense |
probably damaging |
0.99 |
|
holy_grail
|
UTSW |
7 |
26,081,837 (GRCm39) |
missense |
probably benign |
|
|
IGL03054:Nlrp9c
|
UTSW |
7 |
26,081,701 (GRCm39) |
splice site |
probably null |
|
|
K7894:Nlrp9c
|
UTSW |
7 |
26,084,323 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0018:Nlrp9c
|
UTSW |
7 |
26,071,423 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0018:Nlrp9c
|
UTSW |
7 |
26,071,423 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0238:Nlrp9c
|
UTSW |
7 |
26,077,437 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0238:Nlrp9c
|
UTSW |
7 |
26,077,437 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0335:Nlrp9c
|
UTSW |
7 |
26,093,561 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0391:Nlrp9c
|
UTSW |
7 |
26,070,901 (GRCm39) |
splice site |
probably benign |
|
|
R0433:Nlrp9c
|
UTSW |
7 |
26,085,244 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1035:Nlrp9c
|
UTSW |
7 |
26,070,702 (GRCm39) |
splice site |
probably benign |
|
|
R1118:Nlrp9c
|
UTSW |
7 |
26,083,862 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1119:Nlrp9c
|
UTSW |
7 |
26,083,862 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1173:Nlrp9c
|
UTSW |
7 |
26,079,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1519:Nlrp9c
|
UTSW |
7 |
26,077,526 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1528:Nlrp9c
|
UTSW |
7 |
26,081,723 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Nlrp9c
|
UTSW |
7 |
26,083,862 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1774:Nlrp9c
|
UTSW |
7 |
26,093,543 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1789:Nlrp9c
|
UTSW |
7 |
26,079,915 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1869:Nlrp9c
|
UTSW |
7 |
26,084,245 (GRCm39) |
nonsense |
probably null |
|
|
R1870:Nlrp9c
|
UTSW |
7 |
26,084,245 (GRCm39) |
nonsense |
probably null |
|
|
R1920:Nlrp9c
|
UTSW |
7 |
26,084,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1987:Nlrp9c
|
UTSW |
7 |
26,077,481 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2309:Nlrp9c
|
UTSW |
7 |
26,077,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2327:Nlrp9c
|
UTSW |
7 |
26,074,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3405:Nlrp9c
|
UTSW |
7 |
26,084,707 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3548:Nlrp9c
|
UTSW |
7 |
26,070,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3846:Nlrp9c
|
UTSW |
7 |
26,081,701 (GRCm39) |
splice site |
probably null |
|
|
R4179:Nlrp9c
|
UTSW |
7 |
26,084,086 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4460:Nlrp9c
|
UTSW |
7 |
26,077,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4669:Nlrp9c
|
UTSW |
7 |
26,074,793 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4708:Nlrp9c
|
UTSW |
7 |
26,084,265 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4810:Nlrp9c
|
UTSW |
7 |
26,077,602 (GRCm39) |
splice site |
probably null |
|
|
R4824:Nlrp9c
|
UTSW |
7 |
26,079,989 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4915:Nlrp9c
|
UTSW |
7 |
26,083,885 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4996:Nlrp9c
|
UTSW |
7 |
26,085,172 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5468:Nlrp9c
|
UTSW |
7 |
26,064,425 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5525:Nlrp9c
|
UTSW |
7 |
26,083,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5526:Nlrp9c
|
UTSW |
7 |
26,081,791 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6020:Nlrp9c
|
UTSW |
7 |
26,084,150 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6175:Nlrp9c
|
UTSW |
7 |
26,077,426 (GRCm39) |
splice site |
probably null |
|
|
R6454:Nlrp9c
|
UTSW |
7 |
26,085,199 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6493:Nlrp9c
|
UTSW |
7 |
26,081,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6649:Nlrp9c
|
UTSW |
7 |
26,070,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6653:Nlrp9c
|
UTSW |
7 |
26,070,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6739:Nlrp9c
|
UTSW |
7 |
26,084,850 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6883:Nlrp9c
|
UTSW |
7 |
26,077,556 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7097:Nlrp9c
|
UTSW |
7 |
26,085,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7122:Nlrp9c
|
UTSW |
7 |
26,085,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Nlrp9c
|
UTSW |
7 |
26,084,722 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7365:Nlrp9c
|
UTSW |
7 |
26,070,822 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7378:Nlrp9c
|
UTSW |
7 |
26,064,440 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7427:Nlrp9c
|
UTSW |
7 |
26,070,860 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7450:Nlrp9c
|
UTSW |
7 |
26,064,364 (GRCm39) |
missense |
probably benign |
0.45 |
|
R7999:Nlrp9c
|
UTSW |
7 |
26,084,914 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8036:Nlrp9c
|
UTSW |
7 |
26,070,864 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8056:Nlrp9c
|
UTSW |
7 |
26,085,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8249:Nlrp9c
|
UTSW |
7 |
26,074,778 (GRCm39) |
nonsense |
probably null |
|
|
R8729:Nlrp9c
|
UTSW |
7 |
26,071,428 (GRCm39) |
missense |
probably benign |
0.12 |
|
R9012:Nlrp9c
|
UTSW |
7 |
26,074,733 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9104:Nlrp9c
|
UTSW |
7 |
26,081,837 (GRCm39) |
missense |
probably benign |
|
|
R9106:Nlrp9c
|
UTSW |
7 |
26,081,837 (GRCm39) |
missense |
probably benign |
|
|
R9129:Nlrp9c
|
UTSW |
7 |
26,077,428 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9519:Nlrp9c
|
UTSW |
7 |
26,085,302 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
RF020:Nlrp9c
|
UTSW |
7 |
26,084,649 (GRCm39) |
missense |
probably benign |
|
|
X0065:Nlrp9c
|
UTSW |
7 |
26,079,855 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Nlrp9c
|
UTSW |
7 |
26,084,250 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
Z1177:Nlrp9c
|
UTSW |
7 |
26,084,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nlrp9c
|
UTSW |
7 |
26,081,773 (GRCm39) |
missense |
probably benign |
0.28 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTCTGGTTGACTGAGACTTTTAAGG -3'
(R):5'- TGTGCACCTTGGCTGTAGAG -3'
Sequencing Primer
(F):5'- TGTTTTGAATGATATATTGCCAAAGC -3'
(R):5'- CACCTTGGCTGTAGAGGGAATG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation