Incidental Mutation 'R2022:Dip2c'
| ID |
224190 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2c
|
| Ensembl Gene |
ENSMUSG00000048264 |
| Gene Name |
disco interacting protein 2 homolog C |
| Synonyms |
2900024P20Rik |
| MMRRC Submission |
040031-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.589)
|
| Stock # |
R2022 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
9326564-9718964 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 9601836 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 265
(L265P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133806
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166299]
[ENSMUST00000169960]
[ENSMUST00000174552]
|
| AlphaFold |
E9PWR4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166299
AA Change: L265P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000126827
Gene: ENSMUSG00000048264
AA Change: L265P
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
801 |
3.6e-23 |
PFAM |
|
Pfam:AMP-binding
|
977 |
1451 |
1.5e-72 |
PFAM |
|
low complexity region
|
1514 |
1526 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169960
AA Change: L321P
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000131238
Gene: ENSMUSG00000048264
AA Change: L321P
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
176 |
3.02e-37 |
SMART |
|
low complexity region
|
226 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
343 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
380 |
637 |
5.9e-10 |
PFAM |
|
SCOP:d1lci__
|
675 |
875 |
2e-8 |
SMART |
|
Pfam:AMP-binding
|
947 |
1421 |
1.2e-56 |
PFAM |
|
low complexity region
|
1484 |
1496 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000174552
AA Change: L265P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000133806
Gene: ENSMUSG00000048264
AA Change: L265P
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
800 |
2.7e-20 |
PFAM |
|
Pfam:AMP-binding
|
976 |
1450 |
1.3e-56 |
PFAM |
|
low complexity region
|
1513 |
1525 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam34l |
A |
T |
8: 44,078,954 (GRCm39) |
C423* |
probably null |
Het |
| Akr1cl |
T |
A |
1: 65,053,857 (GRCm39) |
Y271F |
probably benign |
Het |
| Asnsd1 |
A |
G |
1: 53,386,386 (GRCm39) |
S414P |
possibly damaging |
Het |
| Atp12a |
T |
A |
14: 56,602,739 (GRCm39) |
M1K |
probably null |
Het |
| Atp4b |
A |
C |
8: 13,437,477 (GRCm39) |
N225K |
possibly damaging |
Het |
| Auh |
G |
A |
13: 52,989,532 (GRCm39) |
P308L |
probably benign |
Het |
| Cactin |
C |
T |
10: 81,158,727 (GRCm39) |
T231I |
possibly damaging |
Het |
| Casp8ap2 |
T |
C |
4: 32,644,560 (GRCm39) |
V1211A |
probably benign |
Het |
| Ccdc180 |
C |
A |
4: 45,944,418 (GRCm39) |
H1423N |
probably benign |
Het |
| Cfap251 |
G |
A |
5: 123,411,853 (GRCm39) |
G495D |
probably benign |
Het |
| Chd9 |
T |
C |
8: 91,761,682 (GRCm39) |
Y2256H |
probably benign |
Het |
| Chst8 |
A |
G |
7: 34,374,589 (GRCm39) |
Y417H |
possibly damaging |
Het |
| Clcn6 |
A |
G |
4: 148,095,109 (GRCm39) |
|
probably null |
Het |
| Clec5a |
A |
T |
6: 40,562,128 (GRCm39) |
V12E |
probably damaging |
Het |
| Crebbp |
C |
T |
16: 3,903,683 (GRCm39) |
R1852H |
probably damaging |
Het |
| Cyp2c40 |
T |
A |
19: 39,801,224 (GRCm39) |
|
probably benign |
Het |
| Dnah3 |
A |
G |
7: 119,550,465 (GRCm39) |
Y3274H |
probably damaging |
Het |
| Dnah6 |
T |
A |
6: 73,004,405 (GRCm39) |
T3853S |
probably benign |
Het |
| Dnttip2 |
T |
C |
3: 122,069,870 (GRCm39) |
S362P |
probably damaging |
Het |
| Dst |
G |
A |
1: 34,205,372 (GRCm39) |
V1025I |
possibly damaging |
Het |
| Dym |
T |
C |
18: 75,213,321 (GRCm39) |
V181A |
probably benign |
Het |
| Dynlt4 |
A |
G |
4: 116,985,504 (GRCm39) |
E109G |
possibly damaging |
Het |
| Elk3 |
T |
A |
10: 93,101,539 (GRCm39) |
I71F |
probably damaging |
Het |
| Epb41l4a |
C |
T |
18: 34,054,893 (GRCm39) |
S65N |
probably benign |
Het |
| Erap1 |
T |
A |
13: 74,814,627 (GRCm39) |
V451E |
probably benign |
Het |
| F830045P16Rik |
T |
A |
2: 129,314,585 (GRCm39) |
I231F |
probably damaging |
Het |
| Fahd1 |
T |
C |
17: 25,068,814 (GRCm39) |
I88V |
probably benign |
Het |
| Fam120b |
C |
T |
17: 15,644,638 (GRCm39) |
T744I |
possibly damaging |
Het |
| Fam83f |
T |
G |
15: 80,576,468 (GRCm39) |
V373G |
possibly damaging |
Het |
| Frem1 |
G |
T |
4: 82,831,795 (GRCm39) |
T1988K |
probably benign |
Het |
| Gdap1l1 |
A |
T |
2: 163,289,517 (GRCm39) |
T161S |
probably benign |
Het |
| Gm6309 |
C |
T |
5: 146,105,121 (GRCm39) |
G264D |
probably benign |
Het |
| Hsd11b1 |
T |
C |
1: 192,922,686 (GRCm39) |
T124A |
probably benign |
Het |
| Ino80b |
A |
G |
6: 83,101,353 (GRCm39) |
M119T |
probably damaging |
Het |
| Kif3a |
G |
A |
11: 53,461,408 (GRCm39) |
V17M |
probably damaging |
Het |
| Krt40 |
T |
A |
11: 99,430,818 (GRCm39) |
E285D |
probably damaging |
Het |
| Lair1 |
C |
G |
7: 4,066,063 (GRCm39) |
|
probably null |
Het |
| Lvrn |
A |
G |
18: 46,999,503 (GRCm39) |
T290A |
possibly damaging |
Het |
| Macf1 |
G |
T |
4: 123,366,523 (GRCm39) |
A2746E |
probably damaging |
Het |
| Matn4 |
A |
G |
2: 164,242,573 (GRCm39) |
V175A |
probably damaging |
Het |
| Mok |
A |
T |
12: 110,778,257 (GRCm39) |
D216E |
probably benign |
Het |
| Muc15 |
A |
T |
2: 110,561,821 (GRCm39) |
T86S |
probably benign |
Het |
| Myo16 |
A |
G |
8: 10,322,633 (GRCm39) |
K21R |
probably benign |
Het |
| Ncl |
A |
G |
1: 86,284,677 (GRCm39) |
|
probably null |
Het |
| Nfrkb |
C |
T |
9: 31,322,546 (GRCm39) |
T872I |
probably benign |
Het |
| Nhlrc2 |
A |
T |
19: 56,585,710 (GRCm39) |
E648D |
probably benign |
Het |
| Nlrp9c |
A |
T |
7: 26,084,221 (GRCm39) |
Y453N |
probably damaging |
Het |
| Notch4 |
T |
C |
17: 34,806,502 (GRCm39) |
L1813P |
probably damaging |
Het |
| Nrg3 |
T |
A |
14: 38,098,309 (GRCm39) |
D515V |
probably damaging |
Het |
| Nsd1 |
T |
C |
13: 55,361,092 (GRCm39) |
V20A |
probably damaging |
Het |
| Opn4 |
T |
A |
14: 34,319,028 (GRCm39) |
T186S |
probably benign |
Het |
| Or9k2 |
T |
C |
10: 129,999,049 (GRCm39) |
M49V |
probably benign |
Het |
| Pcdh15 |
T |
G |
10: 74,467,025 (GRCm39) |
S1684A |
possibly damaging |
Het |
| Phf11a |
T |
A |
14: 59,532,363 (GRCm39) |
E24V |
possibly damaging |
Het |
| Pigg |
A |
T |
5: 108,460,788 (GRCm39) |
|
probably benign |
Het |
| Plscr2 |
A |
G |
9: 92,177,647 (GRCm39) |
D136G |
probably damaging |
Het |
| Ppp3r2 |
T |
C |
4: 49,681,723 (GRCm39) |
I76V |
probably benign |
Het |
| Prdm6 |
A |
G |
18: 53,598,031 (GRCm39) |
|
probably benign |
Het |
| Prex1 |
A |
G |
2: 166,417,534 (GRCm39) |
W1188R |
possibly damaging |
Het |
| Prmt2 |
T |
A |
10: 76,061,292 (GRCm39) |
R65* |
probably null |
Het |
| Prom1 |
G |
T |
5: 44,187,068 (GRCm39) |
D396E |
probably benign |
Het |
| Ptcd3 |
C |
T |
6: 71,862,537 (GRCm39) |
C466Y |
probably damaging |
Het |
| Ptk2 |
A |
G |
15: 73,114,255 (GRCm39) |
V701A |
possibly damaging |
Het |
| Rab36 |
T |
C |
10: 74,888,306 (GRCm39) |
I250T |
probably benign |
Het |
| Rsf1 |
G |
A |
7: 97,229,117 (GRCm39) |
|
probably benign |
Het |
| Scn11a |
G |
T |
9: 119,640,274 (GRCm39) |
A207E |
possibly damaging |
Het |
| Serpinb3d |
A |
G |
1: 107,006,182 (GRCm39) |
V302A |
probably benign |
Het |
| Slc22a16 |
T |
C |
10: 40,467,873 (GRCm39) |
Y469H |
probably damaging |
Het |
| Smo |
A |
G |
6: 29,754,715 (GRCm39) |
N262D |
possibly damaging |
Het |
| Spata31e5 |
A |
T |
1: 28,817,234 (GRCm39) |
V266D |
probably damaging |
Het |
| Sptan1 |
C |
T |
2: 29,897,573 (GRCm39) |
A1212V |
probably damaging |
Het |
| Ssr1 |
C |
T |
13: 38,173,525 (GRCm39) |
A79T |
probably damaging |
Het |
| Tiam1 |
T |
A |
16: 89,674,075 (GRCm39) |
T479S |
probably benign |
Het |
| Tm9sf3 |
A |
G |
19: 41,227,231 (GRCm39) |
F280S |
probably damaging |
Het |
| Tmem72 |
T |
C |
6: 116,673,800 (GRCm39) |
H106R |
probably damaging |
Het |
| Tnr |
A |
G |
1: 159,679,592 (GRCm39) |
I189V |
probably benign |
Het |
| Tpbpa |
T |
A |
13: 61,088,036 (GRCm39) |
N50I |
probably benign |
Het |
| Tshz1 |
T |
A |
18: 84,031,987 (GRCm39) |
Y807F |
probably damaging |
Het |
| Tspo2 |
C |
T |
17: 48,755,750 (GRCm39) |
A131T |
possibly damaging |
Het |
| Usp16 |
T |
C |
16: 87,270,014 (GRCm39) |
L322P |
probably damaging |
Het |
| Vmn1r185 |
A |
G |
7: 26,310,935 (GRCm39) |
V190A |
possibly damaging |
Het |
| Vmn1r34 |
T |
C |
6: 66,614,385 (GRCm39) |
K118E |
possibly damaging |
Het |
| Vmn1r68 |
A |
G |
7: 10,261,918 (GRCm39) |
L60P |
probably damaging |
Het |
| Vmn2r-ps158 |
A |
G |
7: 42,673,454 (GRCm39) |
N171D |
probably benign |
Het |
| Vps51 |
T |
C |
19: 6,121,612 (GRCm39) |
E162G |
probably benign |
Het |
| Yy1 |
CGGG |
CGGGGGG |
12: 108,759,916 (GRCm39) |
|
probably benign |
Het |
| Zdhhc4 |
C |
T |
5: 143,307,538 (GRCm39) |
R161H |
probably damaging |
Het |
| Zfp456 |
A |
T |
13: 67,514,616 (GRCm39) |
C363* |
probably null |
Het |
| Zfp541 |
T |
A |
7: 15,816,110 (GRCm39) |
S866T |
probably damaging |
Het |
|
| Other mutations in Dip2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Dip2c
|
APN |
13 |
9,543,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL00426:Dip2c
|
APN |
13 |
9,656,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00503:Dip2c
|
APN |
13 |
9,617,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00586:Dip2c
|
APN |
13 |
9,660,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01306:Dip2c
|
APN |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01580:Dip2c
|
APN |
13 |
9,687,124 (GRCm39) |
splice site |
probably null |
|
|
IGL01985:Dip2c
|
APN |
13 |
9,603,303 (GRCm39) |
splice site |
probably benign |
|
|
IGL02060:Dip2c
|
APN |
13 |
9,672,666 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02122:Dip2c
|
APN |
13 |
9,556,695 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02170:Dip2c
|
APN |
13 |
9,656,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02211:Dip2c
|
APN |
13 |
9,660,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02755:Dip2c
|
APN |
13 |
9,600,356 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02836:Dip2c
|
APN |
13 |
9,660,826 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02935:Dip2c
|
APN |
13 |
9,712,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03032:Dip2c
|
APN |
13 |
9,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU23:Dip2c
|
UTSW |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
P0038:Dip2c
|
UTSW |
13 |
9,697,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2c
|
UTSW |
13 |
9,671,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0268:Dip2c
|
UTSW |
13 |
9,687,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0271:Dip2c
|
UTSW |
13 |
9,665,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Dip2c
|
UTSW |
13 |
9,654,635 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0415:Dip2c
|
UTSW |
13 |
9,618,325 (GRCm39) |
splice site |
probably benign |
|
|
R0519:Dip2c
|
UTSW |
13 |
9,613,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0557:Dip2c
|
UTSW |
13 |
9,603,495 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0964:Dip2c
|
UTSW |
13 |
9,618,699 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0974:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1101:Dip2c
|
UTSW |
13 |
9,684,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1171:Dip2c
|
UTSW |
13 |
9,543,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1432:Dip2c
|
UTSW |
13 |
9,603,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1481:Dip2c
|
UTSW |
13 |
9,601,902 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1588:Dip2c
|
UTSW |
13 |
9,715,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1721:Dip2c
|
UTSW |
13 |
9,709,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1726:Dip2c
|
UTSW |
13 |
9,625,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1867:Dip2c
|
UTSW |
13 |
9,671,985 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R1909:Dip2c
|
UTSW |
13 |
9,583,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2013:Dip2c
|
UTSW |
13 |
9,617,882 (GRCm39) |
nonsense |
probably null |
|
|
R2517:Dip2c
|
UTSW |
13 |
9,659,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3746:Dip2c
|
UTSW |
13 |
9,651,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3794:Dip2c
|
UTSW |
13 |
9,654,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3884:Dip2c
|
UTSW |
13 |
9,601,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4019:Dip2c
|
UTSW |
13 |
9,664,401 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4110:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4113:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4256:Dip2c
|
UTSW |
13 |
9,659,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4300:Dip2c
|
UTSW |
13 |
9,660,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4494:Dip2c
|
UTSW |
13 |
9,621,098 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4739:Dip2c
|
UTSW |
13 |
9,583,375 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4812:Dip2c
|
UTSW |
13 |
9,687,166 (GRCm39) |
nonsense |
probably null |
|
|
R4814:Dip2c
|
UTSW |
13 |
9,586,896 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4816:Dip2c
|
UTSW |
13 |
9,625,186 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4828:Dip2c
|
UTSW |
13 |
9,610,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4917:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4932:Dip2c
|
UTSW |
13 |
9,674,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4993:Dip2c
|
UTSW |
13 |
9,625,259 (GRCm39) |
nonsense |
probably null |
|
|
R5043:Dip2c
|
UTSW |
13 |
9,601,863 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5349:Dip2c
|
UTSW |
13 |
9,672,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Dip2c
|
UTSW |
13 |
9,618,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:Dip2c
|
UTSW |
13 |
9,556,712 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6110:Dip2c
|
UTSW |
13 |
9,673,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6160:Dip2c
|
UTSW |
13 |
9,583,290 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6161:Dip2c
|
UTSW |
13 |
9,697,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6477:Dip2c
|
UTSW |
13 |
9,673,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6522:Dip2c
|
UTSW |
13 |
9,625,264 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6603:Dip2c
|
UTSW |
13 |
9,704,624 (GRCm39) |
splice site |
probably null |
|
|
R6658:Dip2c
|
UTSW |
13 |
9,543,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6672:Dip2c
|
UTSW |
13 |
9,617,866 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6697:Dip2c
|
UTSW |
13 |
9,671,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,684,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,601,896 (GRCm39) |
nonsense |
probably null |
|
|
R7018:Dip2c
|
UTSW |
13 |
9,709,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7053:Dip2c
|
UTSW |
13 |
9,660,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Dip2c
|
UTSW |
13 |
9,654,572 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7171:Dip2c
|
UTSW |
13 |
9,556,684 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7371:Dip2c
|
UTSW |
13 |
9,642,785 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7395:Dip2c
|
UTSW |
13 |
9,664,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7489:Dip2c
|
UTSW |
13 |
9,583,348 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7575:Dip2c
|
UTSW |
13 |
9,678,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7642:Dip2c
|
UTSW |
13 |
9,672,741 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7687:Dip2c
|
UTSW |
13 |
9,654,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7699:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7700:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7715:Dip2c
|
UTSW |
13 |
9,664,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7842:Dip2c
|
UTSW |
13 |
9,656,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7845:Dip2c
|
UTSW |
13 |
9,659,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8354:Dip2c
|
UTSW |
13 |
9,671,918 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8685:Dip2c
|
UTSW |
13 |
9,687,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8779:Dip2c
|
UTSW |
13 |
9,660,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8786:Dip2c
|
UTSW |
13 |
9,665,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8815:Dip2c
|
UTSW |
13 |
9,673,834 (GRCm39) |
nonsense |
probably null |
|
|
R8833:Dip2c
|
UTSW |
13 |
9,625,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8868:Dip2c
|
UTSW |
13 |
9,625,503 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8873:Dip2c
|
UTSW |
13 |
9,625,182 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8887:Dip2c
|
UTSW |
13 |
9,673,989 (GRCm39) |
splice site |
probably benign |
|
|
R8923:Dip2c
|
UTSW |
13 |
9,673,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9112:Dip2c
|
UTSW |
13 |
9,660,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9424:Dip2c
|
UTSW |
13 |
9,709,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9474:Dip2c
|
UTSW |
13 |
9,544,963 (GRCm39) |
missense |
unknown |
|
|
R9527:Dip2c
|
UTSW |
13 |
9,544,875 (GRCm39) |
missense |
unknown |
|
|
R9593:Dip2c
|
UTSW |
13 |
9,704,683 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9615:Dip2c
|
UTSW |
13 |
9,625,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9801:Dip2c
|
UTSW |
13 |
9,626,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGAGGTACAGGTCAGTGC -3'
(R):5'- CTGAGGGAAGGCTGGATTATCAC -3'
Sequencing Primer
(F):5'- TACAGGTCAGTGCTTAGACAC -3'
(R):5'- GGGAAGGCTGGATTATCACTCTTAAC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation