Incidental Mutation 'R1998:Prrc2c'
| ID |
224484 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prrc2c
|
| Ensembl Gene |
ENSMUSG00000040225 |
| Gene Name |
proline-rich coiled-coil 2C |
| Synonyms |
9630039I18Rik, Bat2d, 1810043M20Rik, Bat2l2 |
| MMRRC Submission |
040008-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.513)
|
| Stock # |
R1998 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
162499354-162568125 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
T to A
at 162532487 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138698
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028016]
[ENSMUST00000182149]
[ENSMUST00000182393]
[ENSMUST00000182593]
[ENSMUST00000182660]
[ENSMUST00000183223]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
unknown
Transcript: ENSMUST00000028016
AA Change: D1374V
|
| SMART Domains |
Protein: ENSMUSP00000028016
Gene: ENSMUSG00000040225
AA Change: D1374V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
164 |
7.7e-56 |
PFAM |
|
internal_repeat_2
|
167 |
349 |
4.39e-5 |
PROSPERO |
|
internal_repeat_1
|
336 |
391 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
407 |
414 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
447 |
591 |
2e-5 |
SMART |
|
low complexity region
|
649 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
745 |
N/A |
INTRINSIC |
|
coiled coil region
|
996 |
1026 |
N/A |
INTRINSIC |
|
low complexity region
|
1157 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1212 |
1222 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1240 |
1295 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
1308 |
1335 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1409 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1765 |
1803 |
N/A |
INTRINSIC |
|
low complexity region
|
1815 |
1832 |
N/A |
INTRINSIC |
|
low complexity region
|
1844 |
1909 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1962 |
2148 |
4.39e-5 |
PROSPERO |
|
low complexity region
|
2163 |
2177 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2272 |
2286 |
N/A |
INTRINSIC |
|
low complexity region
|
2321 |
2338 |
N/A |
INTRINSIC |
|
low complexity region
|
2427 |
2438 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2576 |
N/A |
INTRINSIC |
|
low complexity region
|
2811 |
2828 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000182149
AA Change: D1376V
|
| SMART Domains |
Protein: ENSMUSP00000138548
Gene: ENSMUSG00000040225
AA Change: D1376V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
167 |
5.6e-73 |
PFAM |
|
internal_repeat_1
|
336 |
391 |
1.49e-5 |
PROSPERO |
|
low complexity region
|
407 |
414 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
447 |
591 |
2e-5 |
SMART |
|
low complexity region
|
649 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
745 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
754 |
925 |
9.16e-5 |
PROSPERO |
|
coiled coil region
|
996 |
1026 |
N/A |
INTRINSIC |
|
low complexity region
|
1157 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1212 |
1222 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1240 |
1295 |
1.49e-5 |
PROSPERO |
|
low complexity region
|
1308 |
1335 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1409 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1765 |
1803 |
N/A |
INTRINSIC |
|
low complexity region
|
1815 |
1832 |
N/A |
INTRINSIC |
|
low complexity region
|
1844 |
1909 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1962 |
2148 |
3.08e-5 |
PROSPERO |
|
internal_repeat_3
|
1983 |
2153 |
9.16e-5 |
PROSPERO |
|
low complexity region
|
2163 |
2177 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2272 |
2286 |
N/A |
INTRINSIC |
|
low complexity region
|
2321 |
2338 |
N/A |
INTRINSIC |
|
low complexity region
|
2427 |
2438 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2576 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000182393
AA Change: D92V
|
| SMART Domains |
Protein: ENSMUSP00000138451
Gene: ENSMUSG00000040225
AA Change: D92V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
24 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
104 |
125 |
N/A |
INTRINSIC |
|
low complexity region
|
431 |
462 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
519 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
548 |
N/A |
INTRINSIC |
|
low complexity region
|
560 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
879 |
893 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
968 |
N/A |
INTRINSIC |
|
low complexity region
|
988 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1037 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1154 |
N/A |
INTRINSIC |
|
low complexity region
|
1274 |
1297 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000182593
AA Change: D1374V
|
| SMART Domains |
Protein: ENSMUSP00000138674
Gene: ENSMUSG00000040225
AA Change: D1374V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
165 |
4.1e-70 |
PFAM |
|
internal_repeat_1
|
334 |
389 |
9.57e-6 |
PROSPERO |
|
low complexity region
|
405 |
412 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
445 |
589 |
3e-5 |
SMART |
|
low complexity region
|
647 |
667 |
N/A |
INTRINSIC |
|
low complexity region
|
731 |
743 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
752 |
923 |
6.11e-5 |
PROSPERO |
|
coiled coil region
|
994 |
1024 |
N/A |
INTRINSIC |
|
low complexity region
|
1155 |
1184 |
N/A |
INTRINSIC |
|
low complexity region
|
1210 |
1220 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1238 |
1293 |
9.57e-6 |
PROSPERO |
|
low complexity region
|
1306 |
1333 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1407 |
N/A |
INTRINSIC |
|
low complexity region
|
1713 |
1744 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1801 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1830 |
N/A |
INTRINSIC |
|
low complexity region
|
1842 |
1907 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1960 |
2146 |
2.01e-5 |
PROSPERO |
|
internal_repeat_3
|
1981 |
2151 |
6.11e-5 |
PROSPERO |
|
low complexity region
|
2161 |
2175 |
N/A |
INTRINSIC |
|
low complexity region
|
2228 |
2250 |
N/A |
INTRINSIC |
|
low complexity region
|
2270 |
2284 |
N/A |
INTRINSIC |
|
low complexity region
|
2319 |
2336 |
N/A |
INTRINSIC |
|
low complexity region
|
2425 |
2436 |
N/A |
INTRINSIC |
|
low complexity region
|
2551 |
2574 |
N/A |
INTRINSIC |
|
low complexity region
|
2671 |
2682 |
N/A |
INTRINSIC |
|
low complexity region
|
2730 |
2747 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000182660
AA Change: D1376V
|
| SMART Domains |
Protein: ENSMUSP00000138433
Gene: ENSMUSG00000040225
AA Change: D1376V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
167 |
7e-73 |
PFAM |
|
internal_repeat_1
|
336 |
391 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
407 |
414 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
447 |
591 |
2e-5 |
SMART |
|
low complexity region
|
649 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
745 |
N/A |
INTRINSIC |
|
coiled coil region
|
996 |
1026 |
N/A |
INTRINSIC |
|
low complexity region
|
1157 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1212 |
1222 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1240 |
1295 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
1308 |
1335 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1409 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1765 |
1803 |
N/A |
INTRINSIC |
|
low complexity region
|
1815 |
1832 |
N/A |
INTRINSIC |
|
low complexity region
|
1844 |
1909 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1962 |
2148 |
4.39e-5 |
PROSPERO |
|
low complexity region
|
2163 |
2177 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2272 |
2286 |
N/A |
INTRINSIC |
|
low complexity region
|
2321 |
2338 |
N/A |
INTRINSIC |
|
low complexity region
|
2427 |
2438 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2576 |
N/A |
INTRINSIC |
|
low complexity region
|
2811 |
2828 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183223
|
| SMART Domains |
Protein: ENSMUSP00000138698
Gene: ENSMUSG00000040225
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
289 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
339 |
377 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
406 |
N/A |
INTRINSIC |
|
low complexity region
|
418 |
483 |
N/A |
INTRINSIC |
|
low complexity region
|
739 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
781 |
795 |
N/A |
INTRINSIC |
|
low complexity region
|
830 |
847 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1062 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1182 |
1193 |
N/A |
INTRINSIC |
|
low complexity region
|
1241 |
1258 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310003L06Rik |
T |
G |
5: 88,118,553 (GRCm39) |
N12K |
probably damaging |
Het |
| 2700049A03Rik |
T |
A |
12: 71,235,393 (GRCm39) |
S1114R |
possibly damaging |
Het |
| Acot1 |
T |
A |
12: 84,056,527 (GRCm39) |
W82R |
probably damaging |
Het |
| Adam22 |
T |
C |
5: 8,379,995 (GRCm39) |
D101G |
probably damaging |
Het |
| Adcy9 |
T |
C |
16: 4,115,276 (GRCm39) |
D705G |
probably benign |
Het |
| Adgrg3 |
T |
G |
8: 95,763,296 (GRCm39) |
L244V |
probably damaging |
Het |
| Amh |
AGCGCCTTGG |
AG |
10: 80,641,419 (GRCm39) |
|
probably null |
Het |
| Brinp1 |
C |
T |
4: 68,680,790 (GRCm39) |
G580E |
probably damaging |
Het |
| Brwd1 |
G |
A |
16: 95,822,488 (GRCm39) |
T1239M |
probably damaging |
Het |
| Camk1d |
A |
T |
2: 5,366,836 (GRCm39) |
Y126* |
probably null |
Het |
| Camta1 |
T |
C |
4: 151,162,337 (GRCm39) |
Y1560C |
probably damaging |
Het |
| Cbfa2t2 |
T |
A |
2: 154,346,709 (GRCm39) |
L139M |
probably damaging |
Het |
| Cd226 |
T |
C |
18: 89,225,343 (GRCm39) |
V80A |
probably damaging |
Het |
| Dgka |
C |
T |
10: 128,565,808 (GRCm39) |
V367I |
probably benign |
Het |
| Dnajb13 |
A |
T |
7: 100,153,817 (GRCm39) |
I206N |
probably benign |
Het |
| Dst |
A |
T |
1: 34,295,428 (GRCm39) |
Q5693L |
probably damaging |
Het |
| Ear6 |
T |
A |
14: 52,091,672 (GRCm39) |
I73N |
probably benign |
Het |
| Egr1 |
A |
G |
18: 34,994,587 (GRCm39) |
I16V |
probably benign |
Het |
| Eif2s1 |
T |
A |
12: 78,913,508 (GRCm39) |
C70S |
possibly damaging |
Het |
| Epcam |
T |
C |
17: 87,947,902 (GRCm39) |
V124A |
probably damaging |
Het |
| Erbb2 |
T |
A |
11: 98,319,779 (GRCm39) |
C624S |
probably damaging |
Het |
| Fam135b |
T |
A |
15: 71,324,253 (GRCm39) |
H1238L |
probably damaging |
Het |
| Fam90a1a |
A |
G |
8: 22,453,713 (GRCm39) |
D356G |
probably benign |
Het |
| Fbrsl1 |
G |
A |
5: 110,524,305 (GRCm39) |
S127L |
probably benign |
Het |
| Fndc3c1 |
C |
T |
X: 105,464,311 (GRCm39) |
E1276K |
probably benign |
Het |
| Gbe1 |
A |
T |
16: 70,365,929 (GRCm39) |
N702I |
probably damaging |
Het |
| Gm10643 |
A |
T |
8: 84,791,053 (GRCm39) |
C20* |
probably null |
Het |
| Gpr156 |
A |
G |
16: 37,818,270 (GRCm39) |
N322S |
possibly damaging |
Het |
| Gsdma |
T |
A |
11: 98,564,520 (GRCm39) |
I333N |
probably damaging |
Het |
| Gstm1 |
A |
G |
3: 107,922,127 (GRCm39) |
F170S |
probably damaging |
Het |
| Hgsnat |
C |
T |
8: 26,435,280 (GRCm39) |
W618* |
probably null |
Het |
| Htr5a |
G |
A |
5: 28,055,887 (GRCm39) |
V293M |
possibly damaging |
Het |
| Hyal4 |
A |
G |
6: 24,756,310 (GRCm39) |
E176G |
probably benign |
Het |
| Iqca1l |
G |
A |
5: 24,750,004 (GRCm39) |
R680C |
probably benign |
Het |
| Jag1 |
T |
C |
2: 136,932,858 (GRCm39) |
D546G |
probably damaging |
Het |
| Kbtbd3 |
A |
G |
9: 4,330,760 (GRCm39) |
E378G |
probably benign |
Het |
| Lipo4 |
A |
G |
19: 33,491,701 (GRCm39) |
V94A |
probably damaging |
Het |
| Magea10 |
A |
T |
X: 71,426,379 (GRCm39) |
I205K |
probably benign |
Het |
| Manea |
A |
G |
4: 26,327,871 (GRCm39) |
L390P |
probably damaging |
Het |
| Mars1 |
T |
A |
10: 127,136,347 (GRCm39) |
K493* |
probably null |
Het |
| Mars1 |
T |
C |
10: 127,138,740 (GRCm39) |
I439V |
probably benign |
Het |
| Mboat2 |
A |
G |
12: 24,996,672 (GRCm39) |
D225G |
possibly damaging |
Het |
| Mcmbp |
T |
A |
7: 128,310,887 (GRCm39) |
E350V |
probably damaging |
Het |
| Mki67 |
A |
G |
7: 135,307,499 (GRCm39) |
M459T |
probably benign |
Het |
| Mlf1 |
G |
A |
3: 67,302,624 (GRCm39) |
G150R |
probably damaging |
Het |
| Mtmr14 |
A |
G |
6: 113,254,885 (GRCm39) |
D294G |
probably null |
Het |
| Nlrp4e |
A |
C |
7: 23,020,671 (GRCm39) |
Y386S |
probably benign |
Het |
| Nomo1 |
A |
G |
7: 45,683,368 (GRCm39) |
D38G |
possibly damaging |
Het |
| Nudcd2 |
T |
C |
11: 40,624,844 (GRCm39) |
W18R |
probably damaging |
Het |
| Or11g26 |
T |
A |
14: 50,752,813 (GRCm39) |
C51S |
probably benign |
Het |
| Or3a1b |
A |
G |
11: 74,012,406 (GRCm39) |
Y97C |
probably benign |
Het |
| Or52e4 |
G |
T |
7: 104,706,112 (GRCm39) |
V220L |
probably benign |
Het |
| Or5d16 |
G |
A |
2: 87,773,490 (GRCm39) |
L161F |
probably benign |
Het |
| Or5w16 |
T |
C |
2: 87,577,316 (GRCm39) |
Y259H |
probably damaging |
Het |
| Pcnx2 |
A |
T |
8: 126,613,882 (GRCm39) |
V523D |
probably damaging |
Het |
| Pkd1 |
T |
C |
17: 24,791,988 (GRCm39) |
V1225A |
probably damaging |
Het |
| Plekhh2 |
T |
A |
17: 84,914,305 (GRCm39) |
L1236Q |
possibly damaging |
Het |
| Ppp2r1b |
A |
G |
9: 50,794,885 (GRCm39) |
D570G |
probably damaging |
Het |
| Rai14 |
C |
T |
15: 10,595,067 (GRCm39) |
|
probably null |
Het |
| Rap1gap2 |
A |
G |
11: 74,286,659 (GRCm39) |
L547P |
probably benign |
Het |
| Rims3 |
A |
T |
4: 120,748,555 (GRCm39) |
M259L |
probably benign |
Het |
| Rsbn1l |
G |
A |
5: 21,107,368 (GRCm39) |
H549Y |
probably damaging |
Het |
| Sart3 |
A |
C |
5: 113,885,982 (GRCm39) |
|
probably null |
Het |
| Scn7a |
C |
A |
2: 66,513,613 (GRCm39) |
G1156C |
probably damaging |
Het |
| Sh3rf2 |
T |
A |
18: 42,274,148 (GRCm39) |
V406D |
probably damaging |
Het |
| Slitrk6 |
T |
C |
14: 110,989,255 (GRCm39) |
I151V |
probably damaging |
Het |
| Smarca2 |
A |
T |
19: 26,608,493 (GRCm39) |
Q260L |
probably benign |
Het |
| Smco1 |
A |
G |
16: 32,092,658 (GRCm39) |
R110G |
probably damaging |
Het |
| Spef2 |
T |
A |
15: 9,668,989 (GRCm39) |
|
probably null |
Het |
| Stab1 |
T |
A |
14: 30,884,110 (GRCm39) |
K219* |
probably null |
Het |
| Sulf1 |
G |
T |
1: 12,929,058 (GRCm39) |
E869* |
probably null |
Het |
| Susd1 |
T |
C |
4: 59,349,925 (GRCm39) |
I504V |
probably benign |
Het |
| Szt2 |
A |
G |
4: 118,232,924 (GRCm39) |
|
probably null |
Het |
| Tas1r3 |
A |
T |
4: 155,947,377 (GRCm39) |
C103S |
probably damaging |
Het |
| Thg1l |
C |
A |
11: 45,841,030 (GRCm39) |
W243L |
possibly damaging |
Het |
| Tlr4 |
A |
T |
4: 66,758,707 (GRCm39) |
D500V |
probably damaging |
Het |
| Tmem72 |
A |
G |
6: 116,693,525 (GRCm39) |
V5A |
probably benign |
Het |
| Tns4 |
T |
G |
11: 98,976,529 (GRCm39) |
M131L |
probably benign |
Het |
| Trim66 |
C |
T |
7: 109,083,784 (GRCm39) |
|
probably null |
Het |
| Ttll6 |
T |
A |
11: 96,030,601 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
T |
2: 76,800,047 (GRCm39) |
I387N |
probably damaging |
Het |
| Ubqln5 |
T |
A |
7: 103,777,948 (GRCm39) |
Q292L |
probably damaging |
Het |
| Vmn1r74 |
G |
T |
7: 11,581,302 (GRCm39) |
V201F |
probably damaging |
Het |
| Vmn2r28 |
G |
T |
7: 5,491,313 (GRCm39) |
D311E |
possibly damaging |
Het |
| Vtn |
T |
A |
11: 78,390,542 (GRCm39) |
V67E |
probably damaging |
Het |
| Xirp2 |
T |
A |
2: 67,339,393 (GRCm39) |
F545I |
probably damaging |
Het |
|
| Other mutations in Prrc2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00425:Prrc2c
|
APN |
1 |
162,548,182 (GRCm39) |
splice site |
probably null |
|
|
IGL00577:Prrc2c
|
APN |
1 |
162,525,685 (GRCm39) |
missense |
unknown |
|
|
IGL00580:Prrc2c
|
APN |
1 |
162,525,685 (GRCm39) |
missense |
unknown |
|
|
IGL01295:Prrc2c
|
APN |
1 |
162,510,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01554:Prrc2c
|
APN |
1 |
162,538,355 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01684:Prrc2c
|
APN |
1 |
162,534,031 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01745:Prrc2c
|
APN |
1 |
162,552,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01770:Prrc2c
|
APN |
1 |
162,532,068 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL01905:Prrc2c
|
APN |
1 |
162,532,898 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02304:Prrc2c
|
APN |
1 |
162,511,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02389:Prrc2c
|
APN |
1 |
162,520,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Prrc2c
|
APN |
1 |
162,550,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02681:Prrc2c
|
APN |
1 |
162,533,181 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02686:Prrc2c
|
APN |
1 |
162,535,516 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02795:Prrc2c
|
APN |
1 |
162,541,868 (GRCm39) |
missense |
probably benign |
|
|
IGL02894:Prrc2c
|
APN |
1 |
162,505,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02957:Prrc2c
|
APN |
1 |
162,534,104 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02981:Prrc2c
|
APN |
1 |
162,532,748 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03070:Prrc2c
|
APN |
1 |
162,504,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03096:Prrc2c
|
APN |
1 |
162,529,928 (GRCm39) |
missense |
unknown |
|
|
R0058:Prrc2c
|
UTSW |
1 |
162,526,453 (GRCm39) |
missense |
unknown |
|
|
R0058:Prrc2c
|
UTSW |
1 |
162,526,453 (GRCm39) |
missense |
unknown |
|
|
R0135:Prrc2c
|
UTSW |
1 |
162,543,052 (GRCm39) |
splice site |
probably benign |
|
|
R0279:Prrc2c
|
UTSW |
1 |
162,543,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0363:Prrc2c
|
UTSW |
1 |
162,525,380 (GRCm39) |
missense |
unknown |
|
|
R0436:Prrc2c
|
UTSW |
1 |
162,532,883 (GRCm39) |
unclassified |
probably benign |
|
|
R0605:Prrc2c
|
UTSW |
1 |
162,509,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0696:Prrc2c
|
UTSW |
1 |
162,536,421 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0981:Prrc2c
|
UTSW |
1 |
162,533,550 (GRCm39) |
unclassified |
probably benign |
|
|
R1693:Prrc2c
|
UTSW |
1 |
162,546,282 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1714:Prrc2c
|
UTSW |
1 |
162,504,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Prrc2c
|
UTSW |
1 |
162,532,551 (GRCm39) |
unclassified |
probably benign |
|
|
R1794:Prrc2c
|
UTSW |
1 |
162,533,528 (GRCm39) |
unclassified |
probably benign |
|
|
R2040:Prrc2c
|
UTSW |
1 |
162,525,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2168:Prrc2c
|
UTSW |
1 |
162,537,903 (GRCm39) |
unclassified |
probably benign |
|
|
R2246:Prrc2c
|
UTSW |
1 |
162,535,360 (GRCm39) |
unclassified |
probably benign |
|
|
R2830:Prrc2c
|
UTSW |
1 |
162,536,485 (GRCm39) |
unclassified |
probably benign |
|
|
R2926:Prrc2c
|
UTSW |
1 |
162,533,696 (GRCm39) |
unclassified |
probably benign |
|
|
R3703:Prrc2c
|
UTSW |
1 |
162,538,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3745:Prrc2c
|
UTSW |
1 |
162,525,754 (GRCm39) |
missense |
unknown |
|
|
R3760:Prrc2c
|
UTSW |
1 |
162,520,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3784:Prrc2c
|
UTSW |
1 |
162,537,238 (GRCm39) |
unclassified |
probably benign |
|
|
R3959:Prrc2c
|
UTSW |
1 |
162,536,461 (GRCm39) |
unclassified |
probably benign |
|
|
R4255:Prrc2c
|
UTSW |
1 |
162,533,895 (GRCm39) |
unclassified |
probably benign |
|
|
R4276:Prrc2c
|
UTSW |
1 |
162,501,160 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4421:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R4593:Prrc2c
|
UTSW |
1 |
162,525,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4651:Prrc2c
|
UTSW |
1 |
162,550,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4652:Prrc2c
|
UTSW |
1 |
162,550,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4660:Prrc2c
|
UTSW |
1 |
162,508,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4677:Prrc2c
|
UTSW |
1 |
162,532,748 (GRCm39) |
unclassified |
probably benign |
|
|
R4688:Prrc2c
|
UTSW |
1 |
162,525,256 (GRCm39) |
missense |
unknown |
|
|
R4753:Prrc2c
|
UTSW |
1 |
162,518,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4790:Prrc2c
|
UTSW |
1 |
162,538,050 (GRCm39) |
missense |
unknown |
|
|
R4981:Prrc2c
|
UTSW |
1 |
162,520,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4995:Prrc2c
|
UTSW |
1 |
162,532,879 (GRCm39) |
unclassified |
probably benign |
|
|
R5119:Prrc2c
|
UTSW |
1 |
162,533,009 (GRCm39) |
unclassified |
probably benign |
|
|
R5127:Prrc2c
|
UTSW |
1 |
162,525,415 (GRCm39) |
missense |
unknown |
|
|
R5291:Prrc2c
|
UTSW |
1 |
162,533,151 (GRCm39) |
unclassified |
probably benign |
|
|
R5474:Prrc2c
|
UTSW |
1 |
162,537,213 (GRCm39) |
unclassified |
probably benign |
|
|
R5543:Prrc2c
|
UTSW |
1 |
162,501,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5579:Prrc2c
|
UTSW |
1 |
162,508,327 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5594:Prrc2c
|
UTSW |
1 |
162,526,600 (GRCm39) |
missense |
unknown |
|
|
R5620:Prrc2c
|
UTSW |
1 |
162,501,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5994:Prrc2c
|
UTSW |
1 |
162,501,725 (GRCm39) |
splice site |
probably null |
|
|
R6142:Prrc2c
|
UTSW |
1 |
162,537,956 (GRCm39) |
missense |
unknown |
|
|
R6199:Prrc2c
|
UTSW |
1 |
162,510,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6277:Prrc2c
|
UTSW |
1 |
162,541,883 (GRCm39) |
missense |
probably benign |
|
|
R6504:Prrc2c
|
UTSW |
1 |
162,525,364 (GRCm39) |
missense |
unknown |
|
|
R6671:Prrc2c
|
UTSW |
1 |
162,525,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6785:Prrc2c
|
UTSW |
1 |
162,536,670 (GRCm39) |
unclassified |
probably benign |
|
|
R6799:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6801:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6850:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6851:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6856:Prrc2c
|
UTSW |
1 |
162,509,940 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6869:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6882:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6884:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6897:Prrc2c
|
UTSW |
1 |
162,533,075 (GRCm39) |
unclassified |
probably benign |
|
|
R6934:Prrc2c
|
UTSW |
1 |
162,548,074 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6976:Prrc2c
|
UTSW |
1 |
162,520,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:Prrc2c
|
UTSW |
1 |
162,508,850 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7165:Prrc2c
|
UTSW |
1 |
162,501,086 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7282:Prrc2c
|
UTSW |
1 |
162,507,543 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R7467:Prrc2c
|
UTSW |
1 |
162,504,932 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7915:Prrc2c
|
UTSW |
1 |
162,519,977 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8068:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R8529:Prrc2c
|
UTSW |
1 |
162,536,663 (GRCm39) |
unclassified |
probably benign |
|
|
R8734:Prrc2c
|
UTSW |
1 |
162,507,081 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8735:Prrc2c
|
UTSW |
1 |
162,537,127 (GRCm39) |
missense |
unknown |
|
|
R8813:Prrc2c
|
UTSW |
1 |
162,532,812 (GRCm39) |
missense |
unknown |
|
|
R8946:Prrc2c
|
UTSW |
1 |
162,536,478 (GRCm39) |
unclassified |
probably benign |
|
|
R8975:Prrc2c
|
UTSW |
1 |
162,533,630 (GRCm39) |
missense |
unknown |
|
|
R9035:Prrc2c
|
UTSW |
1 |
162,503,295 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9185:Prrc2c
|
UTSW |
1 |
162,532,212 (GRCm39) |
missense |
unknown |
|
|
R9261:Prrc2c
|
UTSW |
1 |
162,505,622 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R9287:Prrc2c
|
UTSW |
1 |
162,541,843 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9289:Prrc2c
|
UTSW |
1 |
162,507,130 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9466:Prrc2c
|
UTSW |
1 |
162,503,258 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9523:Prrc2c
|
UTSW |
1 |
162,525,298 (GRCm39) |
missense |
unknown |
|
|
R9542:Prrc2c
|
UTSW |
1 |
162,508,359 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9629:Prrc2c
|
UTSW |
1 |
162,519,959 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9744:Prrc2c
|
UTSW |
1 |
162,505,733 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9748:Prrc2c
|
UTSW |
1 |
162,535,435 (GRCm39) |
missense |
unknown |
|
|
X0020:Prrc2c
|
UTSW |
1 |
162,535,416 (GRCm39) |
unclassified |
probably benign |
|
|
X0039:Prrc2c
|
UTSW |
1 |
162,532,362 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CGCAGGTGGATTAACTGGTTC -3'
(R):5'- TAAACCTGGTTTCCTTCCCAAAG -3'
Sequencing Primer
(F):5'- GGTGGATTAACTGGTTCTTGAACAAC -3'
(R):5'- CCTACAAGGCGTGGCAGAG -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation