Mutagenetix > Incidental Mutation

Incidental Mutation 'R0144:Baz2b'

22484

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

MMRRC Submission

038429-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.283) question?

Stock #

R0144 (G1)

Quality Score

225

Status

Validated (trace)

Chromosome

Chromosomal Location

59729707-60040183 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 59737839 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 1823 (N1823K)

Ref Sequence

ENSEMBL: ENSMUSP00000108169 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550]

AlphaFold

A2AUY4

Predicted Effect

probably damaging
Transcript: ENSMUST00000090925
AA Change: N1823K

PolyPhen 2 Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: N1823K

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000112550
AA Change: N1823K

PolyPhen 2 Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: N1823K

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000130637

SMART Domains

Protein: ENSMUSP00000119690
Gene: ENSMUSG00000026987

Domain	Start	End	E-Value	Type
Pfam:WHIM3	2	37	1.8e-13	PFAM
low complexity region	162	173	N/A	INTRINSIC
PHD	214	253	2.05e-1	SMART

Meta Mutation Damage Score

0.2785

Coding Region Coverage

1x: 98.9%
3x: 97.9%
10x: 95.0%
20x: 87.0%

Validation Efficiency

100% (90/90)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 75 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcd4	T	A	12: 84,652,739 (GRCm39)		probably null	Het
Acp6	T	A	3: 97,073,145 (GRCm39)		probably benign	Het
AI661453	A	T	17: 47,780,224 (GRCm39)		probably benign	Het
Aox1	A	G	1: 58,109,233 (GRCm39)	I674V	probably benign	Het
Armc2	A	T	10: 41,823,883 (GRCm39)		probably benign	Het
Atp8b1	G	C	18: 64,704,445 (GRCm39)		probably benign	Het
Bbx	C	T	16: 50,100,755 (GRCm39)	E47K	probably benign	Het
Brca1	A	T	11: 101,416,947 (GRCm39)	S396T	probably damaging	Het
Btnl6	G	T	17: 34,732,994 (GRCm39)	R290S	probably benign	Het
Casp8ap2	A	G	4: 32,643,797 (GRCm39)	R957G	possibly damaging	Het
Ccdc13	A	G	9: 121,656,417 (GRCm39)	L132P	probably damaging	Het
Ccdc187	A	G	2: 26,166,215 (GRCm39)	I738T	probably damaging	Het
Ceacam15	G	T	7: 16,407,116 (GRCm39)	H134N	probably benign	Het
Cep170	T	C	1: 176,620,161 (GRCm39)	I46V	probably benign	Het
Cfap57	T	C	4: 118,441,902 (GRCm39)	D722G	probably damaging	Het
Col11a1	A	T	3: 113,907,243 (GRCm39)	D628V	unknown	Het
Csmd1	A	T	8: 16,441,838 (GRCm39)	V342E	probably benign	Het
Dennd1a	A	G	2: 38,016,652 (GRCm39)	V64A	probably damaging	Het
Dlec1	G	T	9: 118,971,934 (GRCm39)	G1345V	probably benign	Het
Dnah1	G	A	14: 30,989,831 (GRCm39)		probably benign	Het
Dock5	C	T	14: 68,023,735 (GRCm39)	G1142D	probably benign	Het
Etv2	C	A	7: 30,334,308 (GRCm39)	A142S	probably benign	Het
Fam110c	C	A	12: 31,124,500 (GRCm39)	T154K	unknown	Het
Fbxo17	C	G	7: 28,434,765 (GRCm39)	D183E	probably damaging	Het
Fbxo30	T	A	10: 11,170,964 (GRCm39)	W681R	probably damaging	Het
Fig4	A	G	10: 41,134,045 (GRCm39)	Y413H	probably damaging	Het
Gab1	A	G	8: 81,511,830 (GRCm39)		probably benign	Het
Gabarapl1	T	C	6: 129,510,411 (GRCm39)	M1T	probably null	Het
H2-M10.6	G	A	17: 37,123,133 (GRCm39)	C22Y	probably damaging	Het
Igfn1	T	C	1: 135,889,751 (GRCm39)	D2432G	probably damaging	Het
Il13	T	C	11: 53,524,003 (GRCm39)	D60G	possibly damaging	Het
Iqgap1	A	G	7: 80,401,668 (GRCm39)	L479P	probably damaging	Het
Itpr2	T	A	6: 146,228,653 (GRCm39)	Q1314L	probably damaging	Het
Jrk	C	T	15: 74,578,005 (GRCm39)	G427S	probably benign	Het
Kcnb1	T	G	2: 166,946,467 (GRCm39)	N794H	probably damaging	Het
Klhl8	A	T	5: 104,015,804 (GRCm39)	S361R	probably benign	Het
Krt87	T	C	15: 101,336,542 (GRCm39)	Y37C	probably benign	Het
Lbp	A	T	2: 158,161,630 (GRCm39)	S231C	probably damaging	Het
Lpin2	A	G	17: 71,532,071 (GRCm39)	E142G	probably damaging	Het
Lrch4	G	A	5: 137,636,805 (GRCm39)		probably null	Het
Lypd11	A	G	7: 24,423,015 (GRCm39)	V101A	possibly damaging	Het
Manea	A	G	4: 26,340,719 (GRCm39)	M81T	probably benign	Het
Mcm3ap	A	G	10: 76,316,849 (GRCm39)	T618A	probably benign	Het
Me3	A	G	7: 89,389,080 (GRCm39)	D128G	probably damaging	Het
Mix23	A	T	16: 35,905,484 (GRCm39)	N92I	possibly damaging	Het
Mug2	A	G	6: 122,047,970 (GRCm39)		probably benign	Het
Myo9b	A	T	8: 71,798,687 (GRCm39)	Q901L	probably damaging	Het
Nalcn	T	C	14: 123,608,948 (GRCm39)	R640G	probably damaging	Het
Nalcn	C	T	14: 123,647,251 (GRCm39)		probably benign	Het
Ncor1	T	C	11: 62,283,421 (GRCm39)	N422S	probably damaging	Het
Nf1	T	A	11: 79,437,953 (GRCm39)	Y88N	probably damaging	Het
Nrxn3	G	A	12: 89,315,162 (GRCm39)	A358T	probably damaging	Het
Or52s1	A	T	7: 102,861,747 (GRCm39)	I216F	probably damaging	Het
Or5b105	G	A	19: 13,080,642 (GRCm39)	R3C	possibly damaging	Het
Or5p62	T	C	7: 107,771,178 (GRCm39)	I258V	probably benign	Het
Phlpp2	C	T	8: 110,634,145 (GRCm39)	R242W	probably damaging	Het
Pld5	T	C	1: 175,798,107 (GRCm39)	N431D	probably benign	Het
Prss28	G	A	17: 25,528,424 (GRCm39)	V16M	probably damaging	Het
Psmd2	T	A	16: 20,480,975 (GRCm39)		probably null	Het
Ptpn21	A	T	12: 98,654,868 (GRCm39)	S700T	probably benign	Het
Rasa2	A	T	9: 96,474,072 (GRCm39)	V152D	probably damaging	Het
Reln	G	T	5: 22,153,447 (GRCm39)	R2286S	probably damaging	Het
Rflnb	G	T	11: 75,915,789 (GRCm39)	P102Q	probably damaging	Het
Rin2	G	A	2: 145,718,559 (GRCm39)	V680I	probably damaging	Het
Rnf213	A	T	11: 119,370,426 (GRCm39)	K4742*	probably null	Het
Rpp40	A	T	13: 36,085,352 (GRCm39)	S143T	probably benign	Het
Rps12	A	G	10: 23,662,689 (GRCm39)	I51T	probably benign	Het
Rsf1	T	A	7: 97,285,614 (GRCm39)	W109R	probably damaging	Het
Sipa1l2	C	T	8: 126,176,615 (GRCm39)		probably null	Het
Tspan5	G	T	3: 138,604,109 (GRCm39)	V165L	probably damaging	Het
Uts2r	T	A	11: 121,052,291 (GRCm39)	V385E	probably benign	Het
Vma21-ps	T	A	4: 52,497,231 (GRCm39)	D5V	possibly damaging	Het
Vmn2r62	T	A	7: 42,438,440 (GRCm39)	N132I	probably damaging	Het
Zfp622	T	C	15: 25,991,665 (GRCm39)		probably benign	Het
Zmiz1	A	G	14: 25,655,671 (GRCm39)	K766R	probably damaging	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,743,139 (GRCm39)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,744,083 (GRCm39)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,788,019 (GRCm39)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,792,821 (GRCm39)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	59,836,527 (GRCm39)	missense	unknown
IGL01348:Baz2b	APN	2	59,764,031 (GRCm39)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,799,233 (GRCm39)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,765,615 (GRCm39)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,798,984 (GRCm39)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,792,571 (GRCm39)	missense	probably benign
IGL02370:Baz2b	APN	2	59,753,933 (GRCm39)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,790,407 (GRCm39)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,731,840 (GRCm39)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,747,713 (GRCm39)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,778,604 (GRCm39)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,747,849 (GRCm39)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,792,868 (GRCm39)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,807,718 (GRCm39)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,799,002 (GRCm39)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,807,872 (GRCm39)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,788,087 (GRCm39)	splice site	probably null
IGL02892:Baz2b	APN	2	59,731,080 (GRCm39)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,738,097 (GRCm39)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,733,640 (GRCm39)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,731,898 (GRCm39)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,743,963 (GRCm39)	splice site	probably null
R0136:Baz2b	UTSW	2	59,732,298 (GRCm39)	missense	probably benign	0.22
R0403:Baz2b	UTSW	2	59,799,721 (GRCm39)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,732,340 (GRCm39)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,767,083 (GRCm39)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,792,826 (GRCm39)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,752,553 (GRCm39)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,792,368 (GRCm39)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,792,670 (GRCm39)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,778,598 (GRCm39)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,798,981 (GRCm39)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	59,836,474 (GRCm39)	missense	unknown
R1641:Baz2b	UTSW	2	59,743,234 (GRCm39)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,743,336 (GRCm39)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	59,836,480 (GRCm39)	missense	unknown
R1826:Baz2b	UTSW	2	59,799,077 (GRCm39)	missense	probably benign	0.12
R1835:Baz2b	UTSW	2	59,732,163 (GRCm39)	missense	probably benign	0.02
R1954:Baz2b	UTSW	2	59,799,087 (GRCm39)	missense	probably benign	0.12
R1981:Baz2b	UTSW	2	59,754,024 (GRCm39)	missense	possibly damaging	0.95
R2029:Baz2b	UTSW	2	59,743,067 (GRCm39)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,743,348 (GRCm39)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,755,010 (GRCm39)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,799,240 (GRCm39)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,742,917 (GRCm39)	splice site	probably null
R4182:Baz2b	UTSW	2	59,928,801 (GRCm39)	intron	probably benign
R4255:Baz2b	UTSW	2	59,750,916 (GRCm39)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,731,957 (GRCm39)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,799,599 (GRCm39)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	probably benign	0.01
R4772:Baz2b	UTSW	2	59,788,795 (GRCm39)	missense	probably damaging	0.96
R4858:Baz2b	UTSW	2	59,738,087 (GRCm39)	missense	probably benign
R4868:Baz2b	UTSW	2	59,755,226 (GRCm39)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,773,103 (GRCm39)	splice site	probably null
R4889:Baz2b	UTSW	2	59,767,070 (GRCm39)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,756,383 (GRCm39)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	59,928,988 (GRCm39)	intron	probably benign
R5031:Baz2b	UTSW	2	59,743,151 (GRCm39)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,731,835 (GRCm39)	nonsense	probably null
R5133:Baz2b	UTSW	2	59,792,368 (GRCm39)	missense	probably benign	0.12
R5276:Baz2b	UTSW	2	59,792,958 (GRCm39)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,762,496 (GRCm39)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,808,946 (GRCm39)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,744,332 (GRCm39)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,790,233 (GRCm39)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,807,770 (GRCm39)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,742,871 (GRCm39)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,809,019 (GRCm39)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,755,150 (GRCm39)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,778,567 (GRCm39)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,737,292 (GRCm39)	missense	probably damaging	1.00
R6490:Baz2b	UTSW	2	59,732,073 (GRCm39)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,799,623 (GRCm39)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,755,234 (GRCm39)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,792,776 (GRCm39)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,731,874 (GRCm39)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,743,283 (GRCm39)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,799,120 (GRCm39)	missense	probably benign
R6978:Baz2b	UTSW	2	59,738,059 (GRCm39)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,764,014 (GRCm39)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,792,528 (GRCm39)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,742,841 (GRCm39)	missense
R7198:Baz2b	UTSW	2	59,792,550 (GRCm39)	missense	probably benign	0.00
R7270:Baz2b	UTSW	2	59,792,836 (GRCm39)	missense	possibly damaging	0.96
R7282:Baz2b	UTSW	2	59,750,781 (GRCm39)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,807,792 (GRCm39)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,792,817 (GRCm39)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,792,485 (GRCm39)	missense	possibly damaging	0.53
R8079:Baz2b	UTSW	2	59,731,112 (GRCm39)	missense	probably damaging	1.00
R8084:Baz2b	UTSW	2	59,792,580 (GRCm39)	missense	probably benign
R8343:Baz2b	UTSW	2	59,731,858 (GRCm39)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8438:Baz2b	UTSW	2	59,747,828 (GRCm39)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8511:Baz2b	UTSW	2	59,732,158 (GRCm39)	missense	probably benign
R8893:Baz2b	UTSW	2	59,755,149 (GRCm39)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,778,583 (GRCm39)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,799,608 (GRCm39)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,743,993 (GRCm39)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,743,331 (GRCm39)	missense	probably benign
R9577:Baz2b	UTSW	2	59,809,031 (GRCm39)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,799,300 (GRCm39)	missense	probably benign
R9601:Baz2b	UTSW	2	59,731,847 (GRCm39)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,731,824 (GRCm39)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,731,828 (GRCm39)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,807,705 (GRCm39)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,731,019 (GRCm39)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,799,626 (GRCm39)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,790,359 (GRCm39)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,807,864 (GRCm39)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,807,749 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AGCACCATGCAAGTAGCATGATCC -3'
(R):5'- TGCCAATCCTTTGCTGGAAGTCATC -3'

Sequencing Primer
(F):5'- TGATCCACGTGGATCACAGA -3'
(R):5'- GCTGGAAGTCATCACTAATGTCAC -3'

Posted On

2013-04-16