Incidental Mutation 'R0145:Cfap44'
| ID |
22596 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfap44
|
| Ensembl Gene |
ENSMUSG00000071550 |
| Gene Name |
cilia and flagella associated protein 44 |
| Synonyms |
Wdr52, 6330444M21Rik, D16Ertd642e |
| MMRRC Submission |
038430-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0145 (G1)
of strain
722
|
| Quality Score |
186 |
|
Status
|
Validated
(trace)
|
| Chromosome |
16 |
| Chromosomal Location |
44215159-44302791 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 44288735 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 1495
(D1495V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113908
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099742]
[ENSMUST00000120049]
|
| AlphaFold |
E9Q5M6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099742
AA Change: D1495V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000097331
Gene: ENSMUSG00000071550
AA Change: D1495V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
Blast:WD40
|
161 |
201 |
1e-7 |
BLAST |
|
WD40
|
204 |
246 |
4.58e1 |
SMART |
|
WD40
|
249 |
288 |
4.62e-1 |
SMART |
|
Blast:WD40
|
292 |
337 |
2e-15 |
BLAST |
|
WD40
|
342 |
381 |
4.8e-2 |
SMART |
|
WD40
|
447 |
486 |
4.95e-4 |
SMART |
|
WD40
|
491 |
532 |
2.64e2 |
SMART |
|
WD40
|
552 |
591 |
2.98e-7 |
SMART |
|
Blast:WD40
|
595 |
634 |
1e-19 |
BLAST |
|
coiled coil region
|
669 |
711 |
N/A |
INTRINSIC |
|
WD40
|
780 |
820 |
3.82e1 |
SMART |
|
WD40
|
830 |
872 |
2.4e-2 |
SMART |
|
coiled coil region
|
907 |
955 |
N/A |
INTRINSIC |
|
coiled coil region
|
1101 |
1122 |
N/A |
INTRINSIC |
|
low complexity region
|
1266 |
1295 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1325 |
N/A |
INTRINSIC |
|
coiled coil region
|
1402 |
1459 |
N/A |
INTRINSIC |
|
low complexity region
|
1476 |
1488 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1523 |
N/A |
INTRINSIC |
|
coiled coil region
|
1543 |
1607 |
N/A |
INTRINSIC |
|
coiled coil region
|
1630 |
1731 |
N/A |
INTRINSIC |
|
coiled coil region
|
1795 |
1822 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000120049
AA Change: D1495V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000113908
Gene: ENSMUSG00000071550
AA Change: D1495V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
Blast:WD40
|
161 |
201 |
1e-7 |
BLAST |
|
WD40
|
204 |
246 |
4.58e1 |
SMART |
|
WD40
|
249 |
288 |
4.62e-1 |
SMART |
|
Blast:WD40
|
292 |
337 |
2e-15 |
BLAST |
|
WD40
|
342 |
381 |
4.8e-2 |
SMART |
|
WD40
|
447 |
486 |
4.95e-4 |
SMART |
|
WD40
|
491 |
532 |
2.64e2 |
SMART |
|
WD40
|
552 |
591 |
2.98e-7 |
SMART |
|
Blast:WD40
|
595 |
634 |
1e-19 |
BLAST |
|
coiled coil region
|
669 |
711 |
N/A |
INTRINSIC |
|
WD40
|
780 |
820 |
3.82e1 |
SMART |
|
WD40
|
830 |
872 |
2.4e-2 |
SMART |
|
coiled coil region
|
907 |
955 |
N/A |
INTRINSIC |
|
coiled coil region
|
1101 |
1122 |
N/A |
INTRINSIC |
|
low complexity region
|
1266 |
1295 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1325 |
N/A |
INTRINSIC |
|
coiled coil region
|
1402 |
1459 |
N/A |
INTRINSIC |
|
low complexity region
|
1476 |
1488 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1523 |
N/A |
INTRINSIC |
|
coiled coil region
|
1543 |
1607 |
N/A |
INTRINSIC |
|
coiled coil region
|
1630 |
1731 |
N/A |
INTRINSIC |
|
coiled coil region
|
1795 |
1822 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000115502
Gene: ENSMUSG00000071550
AA Change: D126V
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
33 |
90 |
N/A |
INTRINSIC |
|
low complexity region
|
108 |
120 |
N/A |
INTRINSIC |
|
low complexity region
|
121 |
155 |
N/A |
INTRINSIC |
|
coiled coil region
|
174 |
238 |
N/A |
INTRINSIC |
|
coiled coil region
|
261 |
362 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127303
|
| Meta Mutation Damage Score |
0.0827 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 97.8%
- 10x: 93.7%
- 20x: 82.1%
|
| Validation Efficiency |
96% (109/113) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete male sterility, asthenozoospermia, and teratozoospermia characterized by multiple sperm axonemal defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017N19Rik |
A |
G |
10: 100,437,783 (GRCm39) |
E64G |
probably damaging |
Het |
| Actr6 |
A |
T |
10: 89,564,040 (GRCm39) |
Y77* |
probably null |
Het |
| Aldoart1 |
A |
T |
4: 72,769,576 (GRCm39) |
S411T |
probably benign |
Het |
| Aqp1 |
C |
T |
6: 55,323,672 (GRCm39) |
R234C |
probably damaging |
Het |
| Arsb |
G |
A |
13: 93,998,795 (GRCm39) |
G368R |
possibly damaging |
Het |
| Asxl3 |
G |
A |
18: 22,586,662 (GRCm39) |
A151T |
probably damaging |
Het |
| Bcas3 |
T |
C |
11: 85,250,436 (GRCm39) |
|
probably benign |
Het |
| Bmpr2 |
AACACA |
AACA |
1: 59,906,739 (GRCm39) |
|
probably null |
Het |
| Bst1 |
A |
G |
5: 43,976,414 (GRCm39) |
Y49C |
probably damaging |
Het |
| Btrc |
T |
A |
19: 45,411,612 (GRCm39) |
L12Q |
probably damaging |
Het |
| Cd248 |
T |
C |
19: 5,119,051 (GRCm39) |
F300L |
possibly damaging |
Het |
| Cdk11b |
G |
T |
4: 155,726,076 (GRCm39) |
|
probably benign |
Het |
| Cfap410 |
T |
C |
10: 77,819,390 (GRCm39) |
S196P |
probably benign |
Het |
| Chil3 |
T |
A |
3: 106,067,794 (GRCm39) |
I124F |
probably damaging |
Het |
| Cnot2 |
A |
T |
10: 116,353,273 (GRCm39) |
S63T |
possibly damaging |
Het |
| Cox8a |
G |
T |
19: 7,192,783 (GRCm39) |
H61N |
probably benign |
Het |
| Cpne9 |
T |
C |
6: 113,277,562 (GRCm39) |
V427A |
probably damaging |
Het |
| Ctsll3 |
C |
A |
13: 60,946,409 (GRCm39) |
G301C |
probably damaging |
Het |
| Cubn |
T |
A |
2: 13,311,243 (GRCm39) |
D3094V |
probably damaging |
Het |
| Cyba |
A |
T |
8: 123,153,977 (GRCm39) |
M65K |
possibly damaging |
Het |
| Cyp4f39 |
T |
A |
17: 32,705,934 (GRCm39) |
S342T |
possibly damaging |
Het |
| Daam2 |
T |
C |
17: 49,787,806 (GRCm39) |
I436V |
probably benign |
Het |
| Daglb |
T |
C |
5: 143,460,363 (GRCm39) |
|
probably benign |
Het |
| Dnah7b |
T |
G |
1: 46,262,338 (GRCm39) |
L2067R |
probably damaging |
Het |
| Ep300 |
T |
C |
15: 81,500,328 (GRCm39) |
|
probably null |
Het |
| Esm1 |
A |
G |
13: 113,353,230 (GRCm39) |
N171D |
probably damaging |
Het |
| Fbxl2 |
T |
C |
9: 113,814,393 (GRCm39) |
E266G |
probably damaging |
Het |
| Ficd |
G |
T |
5: 113,876,880 (GRCm39) |
A352S |
probably damaging |
Het |
| H2-Q2 |
A |
G |
17: 35,564,152 (GRCm39) |
D302G |
probably benign |
Het |
| Hacd3 |
A |
T |
9: 64,911,524 (GRCm39) |
|
probably benign |
Het |
| Kbtbd6 |
T |
A |
14: 79,690,464 (GRCm39) |
N386K |
probably benign |
Het |
| Lct |
T |
C |
1: 128,255,632 (GRCm39) |
M137V |
probably benign |
Het |
| Lilrb4b |
T |
G |
10: 51,360,614 (GRCm39) |
N176K |
probably benign |
Het |
| Macf1 |
T |
A |
4: 123,281,190 (GRCm39) |
H4340L |
probably damaging |
Het |
| Mcidas |
A |
G |
13: 113,130,906 (GRCm39) |
D77G |
probably damaging |
Het |
| Mmrn1 |
C |
A |
6: 60,949,994 (GRCm39) |
Q315K |
probably damaging |
Het |
| Mon2 |
C |
A |
10: 122,849,417 (GRCm39) |
L1294F |
possibly damaging |
Het |
| Muc5ac |
A |
G |
7: 141,349,012 (GRCm39) |
T483A |
possibly damaging |
Het |
| Nacc1 |
T |
C |
8: 85,401,504 (GRCm39) |
|
probably benign |
Het |
| Nanos3 |
C |
T |
8: 84,902,763 (GRCm39) |
R133Q |
probably damaging |
Het |
| Ngef |
A |
G |
1: 87,468,370 (GRCm39) |
|
probably benign |
Het |
| Nol8 |
C |
T |
13: 49,815,923 (GRCm39) |
A677V |
possibly damaging |
Het |
| Ogfod3 |
A |
T |
11: 121,085,896 (GRCm39) |
|
probably benign |
Het |
| Or6c8 |
A |
T |
10: 128,915,232 (GRCm39) |
V200E |
probably damaging |
Het |
| Or8i2 |
A |
C |
2: 86,852,134 (GRCm39) |
Y251* |
probably null |
Het |
| Parpbp |
T |
C |
10: 87,928,871 (GRCm39) |
Y523C |
possibly damaging |
Het |
| Pik3cg |
C |
A |
12: 32,254,321 (GRCm39) |
L555F |
probably benign |
Het |
| Pkp3 |
T |
G |
7: 140,669,676 (GRCm39) |
|
probably null |
Het |
| Pole |
G |
T |
5: 110,472,291 (GRCm39) |
R1518L |
probably damaging |
Het |
| Prkab1 |
T |
C |
5: 116,156,144 (GRCm39) |
|
probably benign |
Het |
| Prrc2a |
T |
C |
17: 35,374,796 (GRCm39) |
T1285A |
probably benign |
Het |
| Pus1 |
C |
A |
5: 110,922,720 (GRCm39) |
V222L |
probably benign |
Het |
| Rab11fip1 |
A |
G |
8: 27,633,352 (GRCm39) |
L1118P |
probably damaging |
Het |
| Ranbp2 |
T |
A |
10: 58,315,868 (GRCm39) |
I2196N |
probably damaging |
Het |
| Rims3 |
T |
C |
4: 120,744,223 (GRCm39) |
L151P |
probably damaging |
Het |
| Rnf130 |
A |
G |
11: 49,962,046 (GRCm39) |
D164G |
possibly damaging |
Het |
| Rps6ka2 |
C |
A |
17: 7,529,585 (GRCm39) |
L293I |
probably benign |
Het |
| Ruvbl1 |
A |
G |
6: 88,461,441 (GRCm39) |
T269A |
possibly damaging |
Het |
| Sema4a |
A |
T |
3: 88,358,729 (GRCm39) |
I10N |
probably damaging |
Het |
| Serpinb6e |
A |
T |
13: 34,025,043 (GRCm39) |
S83T |
probably benign |
Het |
| Slc12a9 |
C |
A |
5: 137,313,550 (GRCm39) |
W803L |
probably damaging |
Het |
| Slc3a2 |
A |
G |
19: 8,685,437 (GRCm39) |
S188P |
probably damaging |
Het |
| Slc7a13 |
G |
A |
4: 19,818,782 (GRCm39) |
|
probably benign |
Het |
| Spart |
A |
T |
3: 55,035,092 (GRCm39) |
K493* |
probably null |
Het |
| Spata31e2 |
A |
G |
1: 26,726,413 (GRCm39) |
M32T |
probably benign |
Het |
| Sun1 |
T |
C |
5: 139,227,166 (GRCm39) |
V574A |
probably damaging |
Het |
| Supt6 |
A |
G |
11: 78,099,062 (GRCm39) |
V1603A |
probably benign |
Het |
| Tgm5 |
A |
G |
2: 120,908,062 (GRCm39) |
V38A |
possibly damaging |
Het |
| Tm6sf2 |
T |
C |
8: 70,530,518 (GRCm39) |
|
probably benign |
Het |
| Tnfaip2 |
T |
A |
12: 111,412,292 (GRCm39) |
V231E |
possibly damaging |
Het |
| Tube1 |
T |
A |
10: 39,021,598 (GRCm39) |
M281K |
possibly damaging |
Het |
| Tubgcp3 |
A |
G |
8: 12,707,561 (GRCm39) |
Y143H |
probably benign |
Het |
| Tyrp1 |
A |
G |
4: 80,759,015 (GRCm39) |
Y296C |
probably damaging |
Het |
| Utp4 |
A |
G |
8: 107,621,301 (GRCm39) |
N26S |
probably benign |
Het |
| Vgf |
T |
A |
5: 137,060,336 (GRCm39) |
|
probably benign |
Het |
| Zfat |
T |
C |
15: 68,058,948 (GRCm39) |
K196E |
possibly damaging |
Het |
| Zfp366 |
G |
T |
13: 99,366,048 (GRCm39) |
S403I |
probably damaging |
Het |
| Zfp462 |
G |
A |
4: 55,010,529 (GRCm39) |
G832R |
probably damaging |
Het |
| Zfp955a |
T |
A |
17: 33,461,430 (GRCm39) |
Q234L |
probably damaging |
Het |
| Zup1 |
T |
C |
10: 33,819,709 (GRCm39) |
T202A |
probably damaging |
Het |
|
| Other mutations in Cfap44 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Cfap44
|
APN |
16 |
44,227,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00952:Cfap44
|
APN |
16 |
44,241,638 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL01340:Cfap44
|
APN |
16 |
44,224,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01530:Cfap44
|
APN |
16 |
44,269,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02083:Cfap44
|
APN |
16 |
44,257,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02088:Cfap44
|
APN |
16 |
44,271,991 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02142:Cfap44
|
APN |
16 |
44,241,507 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02311:Cfap44
|
APN |
16 |
44,225,134 (GRCm39) |
splice site |
probably benign |
|
|
IGL02574:Cfap44
|
APN |
16 |
44,301,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02893:Cfap44
|
APN |
16 |
44,237,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02959:Cfap44
|
APN |
16 |
44,291,230 (GRCm39) |
splice site |
probably benign |
|
|
IGL03291:Cfap44
|
APN |
16 |
44,227,674 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
feldgrau
|
UTSW |
16 |
44,254,029 (GRCm39) |
nonsense |
probably null |
|
|
I2288:Cfap44
|
UTSW |
16 |
44,269,501 (GRCm39) |
nonsense |
probably null |
|
|
R0023:Cfap44
|
UTSW |
16 |
44,241,583 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0023:Cfap44
|
UTSW |
16 |
44,241,583 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0036:Cfap44
|
UTSW |
16 |
44,259,432 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R0139:Cfap44
|
UTSW |
16 |
44,253,785 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0193:Cfap44
|
UTSW |
16 |
44,269,573 (GRCm39) |
splice site |
probably null |
|
|
R0238:Cfap44
|
UTSW |
16 |
44,242,681 (GRCm39) |
missense |
probably benign |
|
|
R0238:Cfap44
|
UTSW |
16 |
44,242,681 (GRCm39) |
missense |
probably benign |
|
|
R0288:Cfap44
|
UTSW |
16 |
44,236,257 (GRCm39) |
splice site |
probably benign |
|
|
R0367:Cfap44
|
UTSW |
16 |
44,253,839 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0452:Cfap44
|
UTSW |
16 |
44,252,308 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0531:Cfap44
|
UTSW |
16 |
44,221,789 (GRCm39) |
start codon destroyed |
probably benign |
0.01 |
|
R0722:Cfap44
|
UTSW |
16 |
44,225,039 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0801:Cfap44
|
UTSW |
16 |
44,242,849 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1209:Cfap44
|
UTSW |
16 |
44,242,780 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1215:Cfap44
|
UTSW |
16 |
44,239,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1385:Cfap44
|
UTSW |
16 |
44,291,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1400:Cfap44
|
UTSW |
16 |
44,241,575 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1415:Cfap44
|
UTSW |
16 |
44,301,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1475:Cfap44
|
UTSW |
16 |
44,254,175 (GRCm39) |
splice site |
probably benign |
|
|
R1901:Cfap44
|
UTSW |
16 |
44,242,737 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1902:Cfap44
|
UTSW |
16 |
44,242,737 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1903:Cfap44
|
UTSW |
16 |
44,242,737 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2023:Cfap44
|
UTSW |
16 |
44,236,375 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2126:Cfap44
|
UTSW |
16 |
44,230,838 (GRCm39) |
missense |
probably benign |
0.40 |
|
R2147:Cfap44
|
UTSW |
16 |
44,272,047 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2233:Cfap44
|
UTSW |
16 |
44,271,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2439:Cfap44
|
UTSW |
16 |
44,301,609 (GRCm39) |
unclassified |
probably benign |
|
|
R3015:Cfap44
|
UTSW |
16 |
44,230,832 (GRCm39) |
missense |
probably benign |
0.40 |
|
R4178:Cfap44
|
UTSW |
16 |
44,272,216 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4421:Cfap44
|
UTSW |
16 |
44,242,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4516:Cfap44
|
UTSW |
16 |
44,294,227 (GRCm39) |
nonsense |
probably null |
|
|
R4742:Cfap44
|
UTSW |
16 |
44,269,615 (GRCm39) |
splice site |
probably null |
|
|
R4766:Cfap44
|
UTSW |
16 |
44,236,246 (GRCm39) |
splice site |
probably null |
|
|
R4810:Cfap44
|
UTSW |
16 |
44,271,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4955:Cfap44
|
UTSW |
16 |
44,295,640 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5058:Cfap44
|
UTSW |
16 |
44,240,567 (GRCm39) |
splice site |
probably null |
|
|
R5164:Cfap44
|
UTSW |
16 |
44,301,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5172:Cfap44
|
UTSW |
16 |
44,269,556 (GRCm39) |
missense |
probably benign |
|
|
R5344:Cfap44
|
UTSW |
16 |
44,236,763 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5519:Cfap44
|
UTSW |
16 |
44,224,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5572:Cfap44
|
UTSW |
16 |
44,301,668 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5601:Cfap44
|
UTSW |
16 |
44,280,549 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5625:Cfap44
|
UTSW |
16 |
44,280,710 (GRCm39) |
splice site |
probably null |
|
|
R5638:Cfap44
|
UTSW |
16 |
44,275,894 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5727:Cfap44
|
UTSW |
16 |
44,255,805 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5950:Cfap44
|
UTSW |
16 |
44,300,210 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6057:Cfap44
|
UTSW |
16 |
44,269,460 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6063:Cfap44
|
UTSW |
16 |
44,250,255 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6221:Cfap44
|
UTSW |
16 |
44,257,549 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6277:Cfap44
|
UTSW |
16 |
44,257,669 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6322:Cfap44
|
UTSW |
16 |
44,254,029 (GRCm39) |
nonsense |
probably null |
|
|
R6836:Cfap44
|
UTSW |
16 |
44,224,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6854:Cfap44
|
UTSW |
16 |
44,269,391 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6889:Cfap44
|
UTSW |
16 |
44,224,495 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7233:Cfap44
|
UTSW |
16 |
44,242,771 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7294:Cfap44
|
UTSW |
16 |
44,225,256 (GRCm39) |
intron |
probably benign |
|
|
R7298:Cfap44
|
UTSW |
16 |
44,301,775 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7332:Cfap44
|
UTSW |
16 |
44,250,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7410:Cfap44
|
UTSW |
16 |
44,288,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7455:Cfap44
|
UTSW |
16 |
44,225,147 (GRCm39) |
intron |
probably benign |
|
|
R7456:Cfap44
|
UTSW |
16 |
44,252,305 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7491:Cfap44
|
UTSW |
16 |
44,291,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7587:Cfap44
|
UTSW |
16 |
44,224,469 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7698:Cfap44
|
UTSW |
16 |
44,254,149 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7717:Cfap44
|
UTSW |
16 |
44,250,298 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7953:Cfap44
|
UTSW |
16 |
44,234,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7994:Cfap44
|
UTSW |
16 |
44,252,501 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8043:Cfap44
|
UTSW |
16 |
44,234,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8238:Cfap44
|
UTSW |
16 |
44,235,668 (GRCm39) |
splice site |
probably null |
|
|
R8338:Cfap44
|
UTSW |
16 |
44,239,698 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8678:Cfap44
|
UTSW |
16 |
44,295,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Cfap44
|
UTSW |
16 |
44,225,085 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8785:Cfap44
|
UTSW |
16 |
44,275,895 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8922:Cfap44
|
UTSW |
16 |
44,272,030 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9005:Cfap44
|
UTSW |
16 |
44,280,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9020:Cfap44
|
UTSW |
16 |
44,257,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9110:Cfap44
|
UTSW |
16 |
44,255,923 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9111:Cfap44
|
UTSW |
16 |
44,252,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9126:Cfap44
|
UTSW |
16 |
44,295,619 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9187:Cfap44
|
UTSW |
16 |
44,225,144 (GRCm39) |
intron |
probably benign |
|
|
R9194:Cfap44
|
UTSW |
16 |
44,288,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9251:Cfap44
|
UTSW |
16 |
44,229,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9334:Cfap44
|
UTSW |
16 |
44,239,654 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9336:Cfap44
|
UTSW |
16 |
44,242,807 (GRCm39) |
missense |
probably damaging |
0.97 |
|
V1662:Cfap44
|
UTSW |
16 |
44,269,501 (GRCm39) |
nonsense |
probably null |
|
|
X0060:Cfap44
|
UTSW |
16 |
44,269,437 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1088:Cfap44
|
UTSW |
16 |
44,221,829 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Cfap44
|
UTSW |
16 |
44,252,407 (GRCm39) |
missense |
probably benign |
0.04 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGTGTGGTACATAGATGTTCCCAAGG -3'
(R):5'- AGGAGGACCACCTCTGCGTTGATA -3'
Sequencing Primer
(F):5'- aggggaaggggaggttg -3'
(R):5'- GCGTTGATAGCCCCCATC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation