Incidental Mutation 'R2051:Tnr'
| ID |
226375 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnr
|
| Ensembl Gene |
ENSMUSG00000015829 |
| Gene Name |
tenascin R |
| Synonyms |
J1-tenascin, restrictin, janusin, TN-R |
| MMRRC Submission |
040058-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2051 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
159351339-159759299 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 159719603 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 960
(I960T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141553
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000111669]
[ENSMUST00000192069]
|
| AlphaFold |
Q8BYI9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111669
AA Change: I960T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000107298
Gene: ENSMUSG00000015829
AA Change: I960T
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_like
|
203 |
231 |
3.87e1 |
SMART |
|
EGF_like
|
234 |
262 |
3.16e1 |
SMART |
|
EGF_like
|
265 |
293 |
2.8e1 |
SMART |
|
EGF
|
296 |
324 |
2.43e1 |
SMART |
|
FN3
|
326 |
404 |
4.77e-8 |
SMART |
|
FN3
|
415 |
493 |
3.1e-7 |
SMART |
|
FN3
|
504 |
583 |
2.01e-6 |
SMART |
|
FN3
|
594 |
675 |
1.98e-5 |
SMART |
|
FN3
|
686 |
763 |
3.29e-11 |
SMART |
|
FN3
|
774 |
851 |
3.32e-7 |
SMART |
|
FN3
|
864 |
942 |
3.73e-10 |
SMART |
|
FN3
|
953 |
1031 |
2.28e-5 |
SMART |
|
FN3
|
1041 |
1118 |
8.56e-10 |
SMART |
|
FBG
|
1133 |
1343 |
2.69e-133 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192069
AA Change: I960T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000141553
Gene: ENSMUSG00000015829
AA Change: I960T
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_like
|
203 |
231 |
3.87e1 |
SMART |
|
EGF_like
|
234 |
262 |
3.16e1 |
SMART |
|
EGF_like
|
265 |
293 |
2.8e1 |
SMART |
|
EGF
|
296 |
324 |
2.43e1 |
SMART |
|
FN3
|
326 |
404 |
4.77e-8 |
SMART |
|
FN3
|
415 |
493 |
3.1e-7 |
SMART |
|
FN3
|
504 |
583 |
2.01e-6 |
SMART |
|
FN3
|
594 |
675 |
1.98e-5 |
SMART |
|
FN3
|
686 |
763 |
3.29e-11 |
SMART |
|
FN3
|
774 |
851 |
3.32e-7 |
SMART |
|
FN3
|
864 |
942 |
3.73e-10 |
SMART |
|
FN3
|
953 |
1031 |
2.28e-5 |
SMART |
|
FN3
|
1041 |
1118 |
8.56e-10 |
SMART |
|
FBG
|
1133 |
1343 |
2.69e-133 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of sodium channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013]
PHENOTYPE: In spite of having decreased conduction velocity in the optic nerve and ultrastrucural alterations within the hippocampus, homozygous null mice are viable, fertile, and display normal behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700123K08Rik |
G |
A |
5: 138,562,447 (GRCm39) |
T98M |
probably damaging |
Het |
| 4932414N04Rik |
G |
T |
2: 68,541,392 (GRCm39) |
K10N |
possibly damaging |
Het |
| Aadat |
T |
A |
8: 60,960,173 (GRCm39) |
S40T |
probably benign |
Het |
| Abca13 |
A |
G |
11: 9,278,098 (GRCm39) |
I3093V |
probably benign |
Het |
| Acacb |
A |
T |
5: 114,383,951 (GRCm39) |
Q2160L |
probably damaging |
Het |
| Acp6 |
G |
T |
3: 97,075,333 (GRCm39) |
S189I |
probably benign |
Het |
| Actr5 |
A |
T |
2: 158,474,213 (GRCm39) |
M339L |
probably benign |
Het |
| Adcy1 |
A |
T |
11: 7,111,885 (GRCm39) |
K917* |
probably null |
Het |
| Adgrg5 |
C |
T |
8: 95,668,695 (GRCm39) |
R504C |
probably benign |
Het |
| Ago1 |
T |
C |
4: 126,354,246 (GRCm39) |
H188R |
probably benign |
Het |
| Akap9 |
T |
A |
5: 4,025,685 (GRCm39) |
C23* |
probably null |
Het |
| Ank3 |
T |
C |
10: 69,733,920 (GRCm39) |
I728T |
probably damaging |
Het |
| Ankrd50 |
A |
G |
3: 38,508,642 (GRCm39) |
S1242P |
probably benign |
Het |
| Arhgap29 |
G |
A |
3: 121,775,509 (GRCm39) |
R84H |
probably benign |
Het |
| Arhgef10 |
A |
G |
8: 14,995,320 (GRCm39) |
D7G |
probably null |
Het |
| Arid4b |
A |
G |
13: 14,362,230 (GRCm39) |
E898G |
probably damaging |
Het |
| Atrnl1 |
A |
G |
19: 57,680,281 (GRCm39) |
N727S |
probably benign |
Het |
| Baalc |
G |
T |
15: 38,796,629 (GRCm39) |
|
probably benign |
Het |
| Cdc25c |
G |
C |
18: 34,871,292 (GRCm39) |
L275V |
probably damaging |
Het |
| Chpf2 |
G |
T |
5: 24,796,274 (GRCm39) |
V407L |
probably benign |
Het |
| Chrnb3 |
C |
A |
8: 27,876,839 (GRCm39) |
N84K |
probably damaging |
Het |
| Cnot1 |
A |
G |
8: 96,451,221 (GRCm39) |
F2171L |
possibly damaging |
Het |
| Csmd3 |
C |
T |
15: 48,485,389 (GRCm39) |
|
probably null |
Het |
| Cux1 |
T |
A |
5: 136,361,512 (GRCm39) |
Q138L |
probably damaging |
Het |
| Cyp2c65 |
A |
G |
19: 39,070,675 (GRCm39) |
N286S |
probably benign |
Het |
| Dclre1b |
T |
C |
3: 103,716,356 (GRCm39) |
S17G |
possibly damaging |
Het |
| Dlgap5 |
A |
G |
14: 47,648,941 (GRCm39) |
S221P |
probably benign |
Het |
| Dnah1 |
T |
G |
14: 31,001,080 (GRCm39) |
T2422P |
probably damaging |
Het |
| Enpp1 |
A |
G |
10: 24,587,702 (GRCm39) |
|
probably null |
Het |
| Erbb2 |
T |
C |
11: 98,310,998 (GRCm39) |
C53R |
probably damaging |
Het |
| Exoc8 |
A |
G |
8: 125,622,219 (GRCm39) |
V716A |
probably benign |
Het |
| Fam193a |
T |
A |
5: 34,619,494 (GRCm39) |
D766E |
probably benign |
Het |
| Fbxo43 |
C |
A |
15: 36,162,278 (GRCm39) |
G310W |
probably damaging |
Het |
| Fcgbp |
C |
T |
7: 27,819,785 (GRCm39) |
T2504I |
probably damaging |
Het |
| Fnbp4 |
C |
T |
2: 90,587,876 (GRCm39) |
P418L |
probably benign |
Het |
| Gjd2 |
T |
C |
2: 113,841,539 (GRCm39) |
T313A |
probably damaging |
Het |
| Gm12695 |
T |
A |
4: 96,658,008 (GRCm39) |
R54W |
probably damaging |
Het |
| Gm128 |
T |
C |
3: 95,148,051 (GRCm39) |
D81G |
possibly damaging |
Het |
| Gm21834 |
A |
G |
17: 58,048,763 (GRCm39) |
V151A |
possibly damaging |
Het |
| Grhl1 |
T |
A |
12: 24,636,151 (GRCm39) |
|
probably null |
Het |
| Hcn1 |
C |
T |
13: 118,112,619 (GRCm39) |
T861I |
probably damaging |
Het |
| Herc6 |
C |
A |
6: 57,602,961 (GRCm39) |
Q547K |
probably benign |
Het |
| Iqgap3 |
T |
C |
3: 88,027,474 (GRCm39) |
L699P |
probably damaging |
Het |
| Kank4 |
T |
C |
4: 98,668,339 (GRCm39) |
D36G |
probably damaging |
Het |
| Kcnk5 |
A |
T |
14: 20,192,277 (GRCm39) |
S295T |
probably damaging |
Het |
| Krt18 |
T |
C |
15: 101,937,935 (GRCm39) |
V144A |
probably benign |
Het |
| Krtap9-5 |
A |
G |
11: 99,840,030 (GRCm39) |
I244V |
unknown |
Het |
| Leng1 |
T |
G |
7: 3,668,400 (GRCm39) |
N16T |
probably damaging |
Het |
| Lss |
A |
G |
10: 76,367,712 (GRCm39) |
K15E |
possibly damaging |
Het |
| Mastl |
G |
T |
2: 23,022,836 (GRCm39) |
A629E |
possibly damaging |
Het |
| Mavs |
G |
C |
2: 131,082,370 (GRCm39) |
A85P |
possibly damaging |
Het |
| Nav3 |
T |
C |
10: 109,660,536 (GRCm39) |
D678G |
probably damaging |
Het |
| Nsd3 |
T |
G |
8: 26,181,116 (GRCm39) |
S906A |
probably damaging |
Het |
| Nsfl1c |
A |
G |
2: 151,345,002 (GRCm39) |
N118S |
probably damaging |
Het |
| Nup205 |
T |
A |
6: 35,207,451 (GRCm39) |
M1501K |
probably benign |
Het |
| Or4p7 |
C |
T |
2: 88,221,882 (GRCm39) |
T97M |
possibly damaging |
Het |
| Or6n1 |
T |
A |
1: 173,916,785 (GRCm39) |
Y60N |
possibly damaging |
Het |
| Pax8 |
A |
G |
2: 24,326,520 (GRCm39) |
S281P |
probably benign |
Het |
| Pds5b |
T |
G |
5: 150,671,655 (GRCm39) |
I433R |
probably damaging |
Het |
| Peg3 |
T |
C |
7: 6,715,720 (GRCm39) |
N117D |
probably damaging |
Het |
| Pfkm |
A |
T |
15: 98,029,573 (GRCm39) |
D728V |
probably benign |
Het |
| Phkb |
T |
C |
8: 86,776,450 (GRCm39) |
|
probably null |
Het |
| Pkp4 |
T |
C |
2: 59,165,248 (GRCm39) |
V704A |
probably benign |
Het |
| Ppfia2 |
T |
A |
10: 106,673,160 (GRCm39) |
S501T |
probably damaging |
Het |
| Ptpru |
T |
C |
4: 131,546,398 (GRCm39) |
E284G |
possibly damaging |
Het |
| Ror1 |
C |
T |
4: 100,265,065 (GRCm39) |
R180* |
probably null |
Het |
| Ryr3 |
T |
A |
2: 112,586,986 (GRCm39) |
Y2666F |
probably damaging |
Het |
| Sec23a |
C |
A |
12: 59,037,754 (GRCm39) |
|
probably null |
Het |
| Sertad3 |
C |
T |
7: 27,175,694 (GRCm39) |
Q43* |
probably null |
Het |
| Setd2 |
C |
T |
9: 110,379,958 (GRCm39) |
H1258Y |
probably benign |
Het |
| Sharpin |
A |
G |
15: 76,232,407 (GRCm39) |
S177P |
probably benign |
Het |
| Skap1 |
T |
C |
11: 96,432,289 (GRCm39) |
F86S |
possibly damaging |
Het |
| Slc8a2 |
T |
C |
7: 15,874,940 (GRCm39) |
I396T |
probably damaging |
Het |
| Slc9a2 |
T |
C |
1: 40,765,597 (GRCm39) |
F329S |
probably damaging |
Het |
| Slx4ip |
C |
T |
2: 136,908,125 (GRCm39) |
L161F |
possibly damaging |
Het |
| Sox4 |
A |
G |
13: 29,136,764 (GRCm39) |
S81P |
probably damaging |
Het |
| Ssc4d |
G |
T |
5: 135,999,118 (GRCm39) |
S28R |
probably benign |
Het |
| St8sia2 |
C |
T |
7: 73,592,950 (GRCm39) |
G369S |
possibly damaging |
Het |
| Swt1 |
T |
C |
1: 151,248,081 (GRCm39) |
Y836C |
probably damaging |
Het |
| Taar7d |
A |
G |
10: 23,903,904 (GRCm39) |
D262G |
probably benign |
Het |
| Taar8b |
T |
A |
10: 23,967,212 (GRCm39) |
L327F |
probably benign |
Het |
| Tars1 |
A |
T |
15: 11,393,280 (GRCm39) |
L138* |
probably null |
Het |
| Tbcd |
A |
T |
11: 121,344,496 (GRCm39) |
D75V |
probably damaging |
Het |
| Tesc |
A |
G |
5: 118,184,394 (GRCm39) |
I25V |
probably damaging |
Het |
| Tmem132e |
G |
T |
11: 82,331,264 (GRCm39) |
S407I |
probably damaging |
Het |
| Tmem50b |
C |
A |
16: 91,377,180 (GRCm39) |
A95S |
possibly damaging |
Het |
| Tns2 |
C |
T |
15: 102,017,369 (GRCm39) |
R281C |
probably damaging |
Het |
| Tpcn1 |
G |
C |
5: 120,681,453 (GRCm39) |
P532A |
probably damaging |
Het |
| Tpsb2 |
T |
C |
17: 25,585,539 (GRCm39) |
|
probably benign |
Het |
| Triobp |
C |
A |
15: 78,888,740 (GRCm39) |
H1948Q |
probably damaging |
Het |
| Tshb |
T |
C |
3: 102,684,857 (GRCm39) |
I116V |
probably benign |
Het |
| Ttc13 |
A |
T |
8: 125,398,950 (GRCm39) |
|
probably null |
Het |
| Usp34 |
A |
T |
11: 23,414,468 (GRCm39) |
T2804S |
probably damaging |
Het |
| Vmn2r18 |
A |
T |
5: 151,486,016 (GRCm39) |
C493S |
possibly damaging |
Het |
| Vmn2r2 |
T |
C |
3: 64,024,766 (GRCm39) |
K605R |
possibly damaging |
Het |
| Vmn2r37 |
T |
C |
7: 9,220,792 (GRCm39) |
Y357C |
probably damaging |
Het |
| Zc3h6 |
T |
G |
2: 128,857,538 (GRCm39) |
S686A |
possibly damaging |
Het |
| Zfp608 |
G |
A |
18: 55,121,386 (GRCm39) |
P67L |
probably benign |
Het |
| Zyg11a |
T |
C |
4: 108,049,244 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Tnr |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00432:Tnr
|
APN |
1 |
159,688,815 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00905:Tnr
|
APN |
1 |
159,679,752 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01396:Tnr
|
APN |
1 |
159,724,594 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01550:Tnr
|
APN |
1 |
159,701,828 (GRCm39) |
missense |
probably benign |
|
|
IGL01803:Tnr
|
APN |
1 |
159,695,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01845:Tnr
|
APN |
1 |
159,695,576 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01983:Tnr
|
APN |
1 |
159,691,349 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01985:Tnr
|
APN |
1 |
159,746,607 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL02210:Tnr
|
APN |
1 |
159,679,671 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL02486:Tnr
|
APN |
1 |
159,679,664 (GRCm39) |
splice site |
probably null |
|
|
IGL03210:Tnr
|
APN |
1 |
159,715,880 (GRCm39) |
missense |
probably benign |
0.00 |
|
Assiduous
|
UTSW |
1 |
159,719,593 (GRCm39) |
missense |
probably benign |
|
|
Grip
|
UTSW |
1 |
159,713,680 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
Persistent
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
Tenacious
|
UTSW |
1 |
159,701,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0002:Tnr
|
UTSW |
1 |
159,701,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0002:Tnr
|
UTSW |
1 |
159,701,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Tnr
|
UTSW |
1 |
159,679,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0042:Tnr
|
UTSW |
1 |
159,714,595 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0594:Tnr
|
UTSW |
1 |
159,677,905 (GRCm39) |
missense |
probably benign |
|
|
R0617:Tnr
|
UTSW |
1 |
159,695,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0637:Tnr
|
UTSW |
1 |
159,677,905 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R0682:Tnr
|
UTSW |
1 |
159,679,877 (GRCm39) |
nonsense |
probably null |
|
|
R1171:Tnr
|
UTSW |
1 |
159,685,780 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1185:Tnr
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
R1185:Tnr
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
R1185:Tnr
|
UTSW |
1 |
159,679,856 (GRCm39) |
missense |
probably benign |
|
|
R1335:Tnr
|
UTSW |
1 |
159,695,600 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1540:Tnr
|
UTSW |
1 |
159,677,675 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1697:Tnr
|
UTSW |
1 |
159,679,600 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1938:Tnr
|
UTSW |
1 |
159,722,607 (GRCm39) |
nonsense |
probably null |
|
|
R1941:Tnr
|
UTSW |
1 |
159,677,704 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2021:Tnr
|
UTSW |
1 |
159,679,592 (GRCm39) |
missense |
probably benign |
|
|
R2022:Tnr
|
UTSW |
1 |
159,679,592 (GRCm39) |
missense |
probably benign |
|
|
R2157:Tnr
|
UTSW |
1 |
159,685,840 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2319:Tnr
|
UTSW |
1 |
159,677,618 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R2936:Tnr
|
UTSW |
1 |
159,715,932 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3015:Tnr
|
UTSW |
1 |
159,715,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3417:Tnr
|
UTSW |
1 |
159,722,612 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3739:Tnr
|
UTSW |
1 |
159,750,983 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R3977:Tnr
|
UTSW |
1 |
159,719,593 (GRCm39) |
missense |
probably benign |
|
|
R4232:Tnr
|
UTSW |
1 |
159,713,785 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4478:Tnr
|
UTSW |
1 |
159,712,326 (GRCm39) |
splice site |
probably null |
|
|
R4774:Tnr
|
UTSW |
1 |
159,724,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4829:Tnr
|
UTSW |
1 |
159,685,974 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4837:Tnr
|
UTSW |
1 |
159,512,358 (GRCm39) |
intron |
probably benign |
|
|
R5111:Tnr
|
UTSW |
1 |
159,713,798 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5224:Tnr
|
UTSW |
1 |
159,750,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5249:Tnr
|
UTSW |
1 |
159,512,226 (GRCm39) |
intron |
probably benign |
|
|
R5730:Tnr
|
UTSW |
1 |
159,715,892 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5807:Tnr
|
UTSW |
1 |
159,714,500 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5832:Tnr
|
UTSW |
1 |
159,713,692 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5927:Tnr
|
UTSW |
1 |
159,740,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tnr
|
UTSW |
1 |
159,740,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6056:Tnr
|
UTSW |
1 |
159,714,479 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6063:Tnr
|
UTSW |
1 |
159,740,254 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6141:Tnr
|
UTSW |
1 |
159,714,692 (GRCm39) |
missense |
probably benign |
|
|
R6218:Tnr
|
UTSW |
1 |
159,715,884 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6275:Tnr
|
UTSW |
1 |
159,688,840 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6543:Tnr
|
UTSW |
1 |
159,751,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6626:Tnr
|
UTSW |
1 |
159,677,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7378:Tnr
|
UTSW |
1 |
159,712,432 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7587:Tnr
|
UTSW |
1 |
159,713,778 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7766:Tnr
|
UTSW |
1 |
159,715,880 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8140:Tnr
|
UTSW |
1 |
159,691,265 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Tnr
|
UTSW |
1 |
159,715,860 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8248:Tnr
|
UTSW |
1 |
159,719,663 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8374:Tnr
|
UTSW |
1 |
159,685,953 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8427:Tnr
|
UTSW |
1 |
159,713,801 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8465:Tnr
|
UTSW |
1 |
159,713,645 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8534:Tnr
|
UTSW |
1 |
159,746,585 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8753:Tnr
|
UTSW |
1 |
159,677,936 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8804:Tnr
|
UTSW |
1 |
159,685,882 (GRCm39) |
missense |
probably benign |
|
|
R8857:Tnr
|
UTSW |
1 |
159,713,728 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8917:Tnr
|
UTSW |
1 |
159,701,692 (GRCm39) |
nonsense |
probably null |
|
|
R8930:Tnr
|
UTSW |
1 |
159,740,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8932:Tnr
|
UTSW |
1 |
159,740,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8940:Tnr
|
UTSW |
1 |
159,685,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9096:Tnr
|
UTSW |
1 |
159,677,804 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9127:Tnr
|
UTSW |
1 |
159,713,680 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9205:Tnr
|
UTSW |
1 |
159,722,617 (GRCm39) |
missense |
probably benign |
|
|
R9311:Tnr
|
UTSW |
1 |
159,677,663 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9679:Tnr
|
UTSW |
1 |
159,719,608 (GRCm39) |
missense |
probably benign |
0.08 |
|
X0011:Tnr
|
UTSW |
1 |
159,716,908 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0028:Tnr
|
UTSW |
1 |
159,701,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Tnr
|
UTSW |
1 |
159,722,665 (GRCm39) |
missense |
probably benign |
0.29 |
|
Z1177:Tnr
|
UTSW |
1 |
159,679,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATCAGTGGAGCCAGACAGG -3'
(R):5'- GGCTGCATAATTTCTCCAACTTGAG -3'
Sequencing Primer
(F):5'- GGTAGAAAAAGAATCAGTCTCCAC -3'
(R):5'- TTTCTCCAACTTGAGGTAATTTCTG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation