Mutagenetix > Incidental Mutation

Incidental Mutation 'R2054:Bltp1'

226499

Institutional Source

Beutler Lab

Gene Symbol

Bltp1

Ensembl Gene

ENSMUSG00000037270

Gene Name

bridge-like lipid transfer protein family member 1

Synonyms

FSA, 4932438A13Rik, Tweek

MMRRC Submission

040059-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R2054 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

36917253-37107182 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 37002002 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1316 (T1316A)

Ref Sequence

ENSEMBL: ENSMUSP00000148720 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057272] [ENSMUST00000152564] [ENSMUST00000152881] [ENSMUST00000211820]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000057272
AA Change: T1316A

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000060199
Gene: ENSMUSG00000037270
AA Change: T1316A

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000123916

Predicted Effect

probably benign
Transcript: ENSMUST00000128061

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000139219

Predicted Effect

probably benign
Transcript: ENSMUST00000152564
AA Change: T1316A

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000117808
Gene: ENSMUSG00000037270
AA Change: T1316A

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000152881

SMART Domains

Protein: ENSMUSP00000118366
Gene: ENSMUSG00000037270

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000211820
AA Change: T1316A

PolyPhen 2 Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)

Meta Mutation Damage Score

0.0689

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.2%

Validation Efficiency

99% (67/68)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Allele List at MGI

Other mutations in this stock

Total: 67 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2300003K06Rik	A	T	11: 99,728,562 (GRCm39)	C94S	possibly damaging	Het
A930011G23Rik	T	C	5: 99,375,914 (GRCm39)	Y432C	probably benign	Het
Abtb2	A	G	2: 103,535,462 (GRCm39)	D543G	probably benign	Het
Adam9	A	T	8: 25,481,310 (GRCm39)	V318E	probably damaging	Het
Aim2	T	C	1: 173,291,548 (GRCm39)	F318L	probably damaging	Het
Apob	A	T	12: 8,063,134 (GRCm39)	D3872V	probably damaging	Het
Atat1	T	A	17: 36,212,261 (GRCm39)	R323W	probably null	Het
Atp2b4	T	C	1: 133,642,907 (GRCm39)	D1066G	probably benign	Het
Caskin2	T	C	11: 115,697,127 (GRCm39)		probably benign	Het
Cblif	G	A	19: 11,736,370 (GRCm39)	V314I	probably benign	Het
Ccdc54	T	A	16: 50,410,987 (GRCm39)	N93I	probably damaging	Het
Ccnd1	A	C	7: 144,491,128 (GRCm39)	D159E	possibly damaging	Het
Cnot1	A	C	8: 96,466,469 (GRCm39)	S1589R	possibly damaging	Het
Copa	T	A	1: 171,946,524 (GRCm39)	Y980*	probably null	Het
Defb19	A	G	2: 152,418,090 (GRCm39)	I82T	possibly damaging	Het
Elapor2	C	A	5: 9,513,030 (GRCm39)	T1008K	possibly damaging	Het
Fiz1	G	A	7: 5,011,235 (GRCm39)	R428C	probably damaging	Het
Fnip2	A	T	3: 79,479,772 (GRCm39)		probably benign	Het
Gabrb3	G	A	7: 57,474,241 (GRCm39)	G408S	probably benign	Het
Hao1	C	T	2: 134,340,178 (GRCm39)		silent	Het
Hecw1	T	A	13: 14,471,998 (GRCm39)	M557L	probably damaging	Het
Itch	A	T	2: 155,052,496 (GRCm39)	I699F	probably damaging	Het
Kmt2a	T	C	9: 44,734,671 (GRCm39)		probably benign	Het
Leng8	T	G	7: 4,147,289 (GRCm39)	Y562*	probably null	Het
Lonrf2	G	A	1: 38,852,357 (GRCm39)	P165S	probably benign	Het
Lrp1b	A	T	2: 40,587,494 (GRCm39)	N151K	unknown	Het
Lrrc71	T	C	3: 87,649,980 (GRCm39)	E316G	probably damaging	Het
Mgat5	A	G	1: 127,325,344 (GRCm39)	N404D	probably damaging	Het
Mrps26	C	A	2: 130,406,087 (GRCm39)	T100K	probably benign	Het
Mtor	A	G	4: 148,547,309 (GRCm39)	T431A	probably benign	Het
Mtor	T	A	4: 148,550,482 (GRCm39)	C713S	probably benign	Het
Mug2	A	G	6: 122,054,451 (GRCm39)	K1077E	probably damaging	Het
Nbas	A	G	12: 13,524,207 (GRCm39)	T1688A	probably benign	Het
Nek2	T	C	1: 191,553,764 (GRCm39)	S3P	possibly damaging	Het
Nell2	T	C	15: 95,332,990 (GRCm39)	T190A	probably benign	Het
Npr2	A	T	4: 43,646,560 (GRCm39)	N636I	probably damaging	Het
Orc3	A	T	4: 34,584,846 (GRCm39)	I453K	probably damaging	Het
Pcnx1	A	G	12: 81,980,448 (GRCm39)	H865R	probably benign	Het
Pex1	T	C	5: 3,653,341 (GRCm39)	V80A	possibly damaging	Het
Phka2	T	A	X: 159,337,323 (GRCm39)	D424E	probably damaging	Het
Pkd1	C	T	17: 24,793,770 (GRCm39)	T1819I	probably benign	Het
Poglut1	T	C	16: 38,355,169 (GRCm39)	D219G	probably damaging	Het
Ppargc1a	T	C	5: 51,631,130 (GRCm39)	I500V	possibly damaging	Het
Pwwp4a	G	T	X: 72,171,261 (GRCm39)	G218C	probably damaging	Het
Pygm	C	G	19: 6,438,185 (GRCm39)	N163K	probably benign	Het
Qrich1	T	A	9: 108,436,469 (GRCm39)	N722K	possibly damaging	Het
Reep6	T	A	10: 80,166,156 (GRCm39)	C104*	probably null	Het
Rfx8	A	G	1: 39,724,719 (GRCm39)	V214A	possibly damaging	Het
Sis	G	A	3: 72,820,570 (GRCm39)	T1398I	probably benign	Het
Skint5	A	G	4: 113,676,360 (GRCm39)		probably null	Het
Slc7a14	A	G	3: 31,291,511 (GRCm39)		probably benign	Het
Smc2	T	A	4: 52,462,948 (GRCm39)	M646K	probably benign	Het
Snx29	A	G	16: 11,449,356 (GRCm39)	N165S	probably damaging	Het
Supt6	T	A	11: 78,115,187 (GRCm39)		probably benign	Het
Tead4	G	T	6: 128,247,925 (GRCm39)	S37R	probably damaging	Het
Tedc2	T	A	17: 24,435,291 (GRCm39)	E366V	probably damaging	Het
Tedc2	C	A	17: 24,435,292 (GRCm39)	E366*	probably null	Het
Tex56	T	A	13: 35,108,574 (GRCm39)	Y19N	probably damaging	Het
Tff2	T	C	17: 31,362,199 (GRCm39)	K40E	probably benign	Het
Traip	C	T	9: 107,840,118 (GRCm39)	T265M	probably benign	Het
Trim47	T	C	11: 115,999,109 (GRCm39)	T256A	probably benign	Het
Trpm1	A	G	7: 63,890,303 (GRCm39)	M853V	possibly damaging	Het
Tti1	G	T	2: 157,849,365 (GRCm39)	Q625K	possibly damaging	Het
Ube2n	A	G	10: 95,377,128 (GRCm39)	N31S	probably damaging	Het
Vmn2r17	T	C	5: 109,600,352 (GRCm39)	M550T	probably damaging	Het
Zfp512	T	A	5: 31,622,793 (GRCm39)	N31K	probably benign	Het
Zfp64	A	G	2: 168,767,728 (GRCm39)	V628A	probably damaging	Het

Other mutations in Bltp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00428:Bltp1	APN	3	37,065,876 (GRCm39)	missense	probably benign	0.00
IGL00434:Bltp1	APN	3	37,041,448 (GRCm39)	missense	probably damaging	0.98
IGL00640:Bltp1	APN	3	36,962,367 (GRCm39)	missense	probably damaging	1.00
IGL00693:Bltp1	APN	3	37,106,696 (GRCm39)	utr 3 prime	probably benign
IGL00721:Bltp1	APN	3	37,084,900 (GRCm39)	splice site	probably null
IGL00756:Bltp1	APN	3	36,962,367 (GRCm39)	missense	probably damaging	1.00
IGL00896:Bltp1	APN	3	37,093,611 (GRCm39)	missense	probably benign
IGL00902:Bltp1	APN	3	37,095,494 (GRCm39)	missense	probably damaging	1.00
IGL00980:Bltp1	APN	3	37,054,190 (GRCm39)	missense	probably damaging	1.00
IGL01019:Bltp1	APN	3	37,061,133 (GRCm39)	critical splice acceptor site	probably null
IGL01025:Bltp1	APN	3	37,100,429 (GRCm39)	missense	possibly damaging	0.89
IGL01306:Bltp1	APN	3	37,059,162 (GRCm39)	splice site	probably benign
IGL01370:Bltp1	APN	3	37,001,904 (GRCm39)	missense	probably benign	0.07
IGL01377:Bltp1	APN	3	37,027,601 (GRCm39)	critical splice donor site	probably null
IGL01401:Bltp1	APN	3	36,996,441 (GRCm39)	missense	probably benign
IGL01419:Bltp1	APN	3	37,102,270 (GRCm39)	missense	probably damaging	1.00
IGL01432:Bltp1	APN	3	37,057,908 (GRCm39)	missense	possibly damaging	0.87
IGL01433:Bltp1	APN	3	36,941,919 (GRCm39)	missense	probably damaging	1.00
IGL01452:Bltp1	APN	3	37,050,457 (GRCm39)	unclassified	probably benign
IGL01520:Bltp1	APN	3	37,027,409 (GRCm39)	nonsense	probably null
IGL01524:Bltp1	APN	3	36,996,531 (GRCm39)	missense	possibly damaging	0.90
IGL01628:Bltp1	APN	3	37,062,634 (GRCm39)	missense	probably damaging	1.00
IGL01638:Bltp1	APN	3	37,028,460 (GRCm39)	missense	probably damaging	1.00
IGL01650:Bltp1	APN	3	37,046,822 (GRCm39)	splice site	probably benign
IGL01717:Bltp1	APN	3	37,088,885 (GRCm39)	missense	probably benign
IGL01767:Bltp1	APN	3	37,095,512 (GRCm39)	missense	probably benign	0.29
IGL01813:Bltp1	APN	3	36,982,669 (GRCm39)	missense	possibly damaging	0.90
IGL01998:Bltp1	APN	3	37,011,165 (GRCm39)	missense	possibly damaging	0.49
IGL02172:Bltp1	APN	3	37,059,022 (GRCm39)	missense	probably damaging	0.99
IGL02197:Bltp1	APN	3	36,960,884 (GRCm39)	missense	probably damaging	1.00
IGL02248:Bltp1	APN	3	37,023,439 (GRCm39)	critical splice donor site	probably null
IGL02273:Bltp1	APN	3	36,975,586 (GRCm39)	splice site	probably benign
IGL02403:Bltp1	APN	3	37,084,813 (GRCm39)	missense	probably benign
IGL02492:Bltp1	APN	3	37,102,262 (GRCm39)	missense	probably benign	0.04
IGL02517:Bltp1	APN	3	37,013,017 (GRCm39)	missense	probably damaging	1.00
IGL02519:Bltp1	APN	3	36,949,464 (GRCm39)	missense	probably damaging	1.00
IGL02586:Bltp1	APN	3	37,098,757 (GRCm39)	nonsense	probably null
IGL02620:Bltp1	APN	3	37,090,094 (GRCm39)	missense	possibly damaging	0.95
IGL02621:Bltp1	APN	3	37,095,633 (GRCm39)	splice site	probably benign
IGL02670:Bltp1	APN	3	37,021,454 (GRCm39)	nonsense	probably null
IGL02806:Bltp1	APN	3	37,000,643 (GRCm39)	missense	possibly damaging	0.95
IGL02985:Bltp1	APN	3	37,012,906 (GRCm39)	missense	probably damaging	0.99
IGL03004:Bltp1	APN	3	37,019,826 (GRCm39)	splice site	probably benign
IGL03037:Bltp1	APN	3	37,023,356 (GRCm39)	missense	probably benign	0.23
IGL03037:Bltp1	APN	3	37,023,357 (GRCm39)	missense	probably damaging	1.00
IGL03062:Bltp1	APN	3	37,092,666 (GRCm39)	splice site	probably benign
IGL03137:Bltp1	APN	3	37,088,751 (GRCm39)	missense	probably damaging	0.98
IGL03150:Bltp1	APN	3	37,002,215 (GRCm39)	missense	probably damaging	1.00
IGL03204:Bltp1	APN	3	37,105,083 (GRCm39)	splice site	probably benign
IGL03207:Bltp1	APN	3	37,004,145 (GRCm39)	missense	possibly damaging	0.73
IGL03256:Bltp1	APN	3	36,960,832 (GRCm39)	splice site	probably benign
IGL03264:Bltp1	APN	3	37,056,784 (GRCm39)	missense	probably damaging	1.00
IGL03265:Bltp1	APN	3	37,102,140 (GRCm39)	missense	probably benign	0.00
IGL03303:Bltp1	APN	3	36,924,226 (GRCm39)	missense	possibly damaging	0.90
admonished	UTSW	3	37,002,453 (GRCm39)	missense	probably damaging	1.00
alerted	UTSW	3	37,087,414 (GRCm39)	missense	possibly damaging	0.85
informed	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
resolved	UTSW	3	36,975,370 (GRCm39)	missense	possibly damaging	0.60
tipped	UTSW	3	37,042,234 (GRCm39)	missense	possibly damaging	0.81
warned	UTSW	3	37,019,770 (GRCm39)	missense	probably damaging	1.00
FR4340:Bltp1	UTSW	3	37,104,901 (GRCm39)	critical splice acceptor site	probably benign
FR4737:Bltp1	UTSW	3	37,104,903 (GRCm39)	critical splice acceptor site	probably benign
PIT4515001:Bltp1	UTSW	3	37,028,385 (GRCm39)	missense	probably damaging	1.00
R0035:Bltp1	UTSW	3	37,041,747 (GRCm39)	nonsense	probably null
R0047:Bltp1	UTSW	3	36,962,341 (GRCm39)	missense	possibly damaging	0.83
R0047:Bltp1	UTSW	3	36,962,341 (GRCm39)	missense	possibly damaging	0.83
R0068:Bltp1	UTSW	3	37,006,370 (GRCm39)	missense	probably benign	0.28
R0068:Bltp1	UTSW	3	37,006,370 (GRCm39)	missense	probably benign	0.28
R0092:Bltp1	UTSW	3	37,082,308 (GRCm39)	missense	probably benign	0.41
R0233:Bltp1	UTSW	3	37,002,712 (GRCm39)	nonsense	probably null
R0233:Bltp1	UTSW	3	37,002,712 (GRCm39)	nonsense	probably null
R0256:Bltp1	UTSW	3	36,971,922 (GRCm39)	missense	probably benign	0.01
R0277:Bltp1	UTSW	3	36,997,331 (GRCm39)	nonsense	probably null
R0321:Bltp1	UTSW	3	36,960,937 (GRCm39)	splice site	probably null
R0323:Bltp1	UTSW	3	36,997,331 (GRCm39)	nonsense	probably null
R0335:Bltp1	UTSW	3	37,023,301 (GRCm39)	missense	probably damaging	1.00
R0375:Bltp1	UTSW	3	37,100,401 (GRCm39)	missense	probably damaging	0.99
R0437:Bltp1	UTSW	3	37,043,953 (GRCm39)	missense	possibly damaging	0.81
R0445:Bltp1	UTSW	3	37,054,214 (GRCm39)	missense	probably damaging	0.99
R0496:Bltp1	UTSW	3	37,041,784 (GRCm39)	missense	probably damaging	1.00
R0531:Bltp1	UTSW	3	37,090,974 (GRCm39)	missense	probably damaging	1.00
R0543:Bltp1	UTSW	3	37,050,607 (GRCm39)	missense	probably benign	0.22
R0545:Bltp1	UTSW	3	37,041,839 (GRCm39)	splice site	probably benign
R0674:Bltp1	UTSW	3	37,098,775 (GRCm39)	missense	possibly damaging	0.86
R0745:Bltp1	UTSW	3	36,982,612 (GRCm39)	missense	probably damaging	1.00
R0755:Bltp1	UTSW	3	37,000,513 (GRCm39)	missense	probably damaging	1.00
R0785:Bltp1	UTSW	3	37,013,483 (GRCm39)	splice site	probably benign
R1056:Bltp1	UTSW	3	37,098,829 (GRCm39)	missense	probably benign	0.44
R1056:Bltp1	UTSW	3	37,037,602 (GRCm39)	missense	possibly damaging	0.69
R1080:Bltp1	UTSW	3	37,042,404 (GRCm39)	missense	probably damaging	1.00
R1103:Bltp1	UTSW	3	37,050,672 (GRCm39)	missense	probably benign
R1119:Bltp1	UTSW	3	37,041,194 (GRCm39)	missense	probably damaging	1.00
R1170:Bltp1	UTSW	3	37,098,780 (GRCm39)	missense	probably damaging	0.98
R1183:Bltp1	UTSW	3	36,949,452 (GRCm39)	missense	possibly damaging	0.51
R1186:Bltp1	UTSW	3	37,050,461 (GRCm39)	unclassified	probably benign
R1201:Bltp1	UTSW	3	37,002,524 (GRCm39)	missense	probably benign
R1219:Bltp1	UTSW	3	37,000,619 (GRCm39)	nonsense	probably null
R1270:Bltp1	UTSW	3	37,006,333 (GRCm39)	missense	probably damaging	1.00
R1273:Bltp1	UTSW	3	37,041,359 (GRCm39)	missense	probably damaging	1.00
R1338:Bltp1	UTSW	3	37,106,684 (GRCm39)	missense	unknown
R1364:Bltp1	UTSW	3	37,041,179 (GRCm39)	missense	probably damaging	1.00
R1437:Bltp1	UTSW	3	36,996,578 (GRCm39)	missense	possibly damaging	0.65
R1447:Bltp1	UTSW	3	37,019,735 (GRCm39)	missense	probably damaging	0.98
R1467:Bltp1	UTSW	3	37,090,094 (GRCm39)	missense	probably damaging	0.99
R1467:Bltp1	UTSW	3	37,090,094 (GRCm39)	missense	probably damaging	0.99
R1470:Bltp1	UTSW	3	37,052,480 (GRCm39)	missense	probably benign	0.31
R1470:Bltp1	UTSW	3	37,052,480 (GRCm39)	missense	probably benign	0.31
R1481:Bltp1	UTSW	3	37,062,583 (GRCm39)	missense	probably damaging	0.99
R1528:Bltp1	UTSW	3	37,106,684 (GRCm39)	missense	unknown
R1533:Bltp1	UTSW	3	37,095,524 (GRCm39)	missense	probably damaging	1.00
R1546:Bltp1	UTSW	3	36,924,205 (GRCm39)	missense	possibly damaging	0.64
R1606:Bltp1	UTSW	3	36,996,548 (GRCm39)	missense	probably damaging	1.00
R1638:Bltp1	UTSW	3	37,089,961 (GRCm39)	nonsense	probably null
R1772:Bltp1	UTSW	3	37,013,581 (GRCm39)	missense	probably damaging	1.00
R1896:Bltp1	UTSW	3	36,962,380 (GRCm39)	nonsense	probably null
R1919:Bltp1	UTSW	3	37,061,132 (GRCm39)	critical splice acceptor site	probably null
R1983:Bltp1	UTSW	3	36,942,014 (GRCm39)	missense	probably null	1.00
R1987:Bltp1	UTSW	3	37,008,134 (GRCm39)	critical splice donor site	probably null
R1992:Bltp1	UTSW	3	37,054,181 (GRCm39)	missense	probably benign	0.32
R1999:Bltp1	UTSW	3	36,962,360 (GRCm39)	missense	probably damaging	1.00
R2004:Bltp1	UTSW	3	36,949,527 (GRCm39)	missense	possibly damaging	0.77
R2010:Bltp1	UTSW	3	36,982,700 (GRCm39)	missense	probably benign	0.09
R2027:Bltp1	UTSW	3	37,102,110 (GRCm39)	splice site	probably benign
R2039:Bltp1	UTSW	3	37,058,027 (GRCm39)	missense	possibly damaging	0.66
R2089:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,042,405 (GRCm39)	missense	probably damaging	1.00
R2091:Bltp1	UTSW	3	37,008,119 (GRCm39)	missense	probably damaging	1.00
R2220:Bltp1	UTSW	3	36,929,679 (GRCm39)	critical splice donor site	probably null
R2374:Bltp1	UTSW	3	36,939,545 (GRCm39)	missense	probably benign	0.00
R2437:Bltp1	UTSW	3	37,012,834 (GRCm39)	splice site	probably null
R2860:Bltp1	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
R2861:Bltp1	UTSW	3	37,019,998 (GRCm39)	missense	probably damaging	1.00
R2909:Bltp1	UTSW	3	37,002,102 (GRCm39)	missense	probably damaging	1.00
R2925:Bltp1	UTSW	3	37,061,271 (GRCm39)	missense	probably damaging	0.99
R2940:Bltp1	UTSW	3	37,012,954 (GRCm39)	missense	probably damaging	1.00
R3015:Bltp1	UTSW	3	36,929,611 (GRCm39)	missense	probably damaging	1.00
R3086:Bltp1	UTSW	3	37,065,852 (GRCm39)	missense	possibly damaging	0.56
R3159:Bltp1	UTSW	3	37,013,564 (GRCm39)	missense	probably benign	0.17
R3440:Bltp1	UTSW	3	37,096,061 (GRCm39)	nonsense	probably null
R3703:Bltp1	UTSW	3	37,041,730 (GRCm39)	missense	probably damaging	1.00
R3705:Bltp1	UTSW	3	37,041,730 (GRCm39)	missense	probably damaging	1.00
R3795:Bltp1	UTSW	3	37,084,714 (GRCm39)	missense	probably benign	0.30
R3820:Bltp1	UTSW	3	37,094,583 (GRCm39)	missense	probably damaging	1.00
R3862:Bltp1	UTSW	3	36,939,547 (GRCm39)	missense	possibly damaging	0.73
R3944:Bltp1	UTSW	3	37,084,210 (GRCm39)	missense	possibly damaging	0.90
R4020:Bltp1	UTSW	3	37,066,724 (GRCm39)	intron	probably benign
R4091:Bltp1	UTSW	3	37,084,738 (GRCm39)	missense	probably benign	0.00
R4159:Bltp1	UTSW	3	36,985,232 (GRCm39)	missense	probably benign	0.00
R4231:Bltp1	UTSW	3	36,974,385 (GRCm39)	missense	probably benign	0.10
R4368:Bltp1	UTSW	3	37,042,296 (GRCm39)	nonsense	probably null
R4413:Bltp1	UTSW	3	37,012,830 (GRCm39)	splice site	probably null
R4475:Bltp1	UTSW	3	37,094,544 (GRCm39)	missense	probably damaging	1.00
R4488:Bltp1	UTSW	3	37,058,082 (GRCm39)	missense	probably null	0.93
R4489:Bltp1	UTSW	3	37,058,082 (GRCm39)	missense	probably null	0.93
R4516:Bltp1	UTSW	3	36,949,460 (GRCm39)	missense	possibly damaging	0.90
R4580:Bltp1	UTSW	3	37,084,174 (GRCm39)	missense	probably benign	0.02
R4672:Bltp1	UTSW	3	36,944,139 (GRCm39)	makesense	probably null
R4705:Bltp1	UTSW	3	37,096,038 (GRCm39)	missense	probably benign	0.03
R4735:Bltp1	UTSW	3	37,059,116 (GRCm39)	missense	possibly damaging	0.84
R4741:Bltp1	UTSW	3	36,996,524 (GRCm39)	missense	probably damaging	0.99
R4754:Bltp1	UTSW	3	37,076,615 (GRCm39)	nonsense	probably null
R4778:Bltp1	UTSW	3	36,991,214 (GRCm39)	missense	possibly damaging	0.90
R4833:Bltp1	UTSW	3	37,019,117 (GRCm39)	missense	probably damaging	0.96
R4896:Bltp1	UTSW	3	37,020,086 (GRCm39)	missense	probably damaging	1.00
R4910:Bltp1	UTSW	3	37,052,348 (GRCm39)	missense	probably damaging	1.00
R4922:Bltp1	UTSW	3	37,041,314 (GRCm39)	missense	probably damaging	1.00
R4941:Bltp1	UTSW	3	36,974,050 (GRCm39)	missense	probably benign	0.41
R4941:Bltp1	UTSW	3	36,971,851 (GRCm39)	missense	probably damaging	1.00
R4980:Bltp1	UTSW	3	36,997,461 (GRCm39)	missense	probably damaging	1.00
R5030:Bltp1	UTSW	3	36,997,548 (GRCm39)	intron	probably benign
R5049:Bltp1	UTSW	3	37,095,539 (GRCm39)	missense	probably damaging	1.00
R5049:Bltp1	UTSW	3	37,094,655 (GRCm39)	intron	probably benign
R5089:Bltp1	UTSW	3	37,041,651 (GRCm39)	missense	probably benign	0.02
R5092:Bltp1	UTSW	3	37,054,234 (GRCm39)	missense	probably benign	0.14
R5122:Bltp1	UTSW	3	37,088,906 (GRCm39)	splice site	probably null
R5210:Bltp1	UTSW	3	37,087,414 (GRCm39)	missense	possibly damaging	0.85
R5246:Bltp1	UTSW	3	37,102,199 (GRCm39)	missense	probably damaging	1.00
R5289:Bltp1	UTSW	3	37,054,258 (GRCm39)	missense	probably damaging	0.97
R5348:Bltp1	UTSW	3	37,102,295 (GRCm39)	missense	probably damaging	1.00
R5394:Bltp1	UTSW	3	36,971,817 (GRCm39)	missense	probably damaging	1.00
R5434:Bltp1	UTSW	3	36,929,665 (GRCm39)	missense	probably damaging	1.00
R5667:Bltp1	UTSW	3	36,971,826 (GRCm39)	missense	probably benign	0.00
R5686:Bltp1	UTSW	3	36,971,809 (GRCm39)	missense	probably benign	0.00
R5701:Bltp1	UTSW	3	36,975,509 (GRCm39)	missense	probably benign	0.10
R5778:Bltp1	UTSW	3	37,012,863 (GRCm39)	missense	probably damaging	1.00
R5787:Bltp1	UTSW	3	37,046,882 (GRCm39)	splice site	probably null
R5800:Bltp1	UTSW	3	37,106,592 (GRCm39)	missense	probably damaging	1.00
R5819:Bltp1	UTSW	3	37,102,749 (GRCm39)	missense	probably benign	0.12
R5820:Bltp1	UTSW	3	37,093,675 (GRCm39)	missense	probably benign	0.00
R5952:Bltp1	UTSW	3	37,019,770 (GRCm39)	missense	probably damaging	1.00
R5975:Bltp1	UTSW	3	37,023,370 (GRCm39)	missense	possibly damaging	0.64
R5996:Bltp1	UTSW	3	36,985,265 (GRCm39)	missense	probably benign	0.07
R6192:Bltp1	UTSW	3	37,042,318 (GRCm39)	missense	probably benign	0.00
R6225:Bltp1	UTSW	3	37,002,453 (GRCm39)	missense	probably damaging	1.00
R6234:Bltp1	UTSW	3	37,037,620 (GRCm39)	missense	probably benign	0.00
R6244:Bltp1	UTSW	3	37,011,148 (GRCm39)	missense	probably benign
R6263:Bltp1	UTSW	3	36,985,260 (GRCm39)	missense	probably benign	0.06
R6351:Bltp1	UTSW	3	36,962,377 (GRCm39)	missense	probably damaging	1.00
R6380:Bltp1	UTSW	3	37,087,456 (GRCm39)	missense	probably benign	0.19
R6468:Bltp1	UTSW	3	37,062,592 (GRCm39)	missense	probably damaging	1.00
R6759:Bltp1	UTSW	3	37,042,234 (GRCm39)	missense	possibly damaging	0.81
R6792:Bltp1	UTSW	3	37,065,715 (GRCm39)	critical splice acceptor site	probably null
R6809:Bltp1	UTSW	3	36,928,431 (GRCm39)	missense	probably damaging	0.98
R6841:Bltp1	UTSW	3	37,075,630 (GRCm39)	missense	probably damaging	1.00
R6959:Bltp1	UTSW	3	37,021,338 (GRCm39)	missense	probably damaging	1.00
R7102:Bltp1	UTSW	3	36,994,947 (GRCm39)	missense	probably damaging	0.99
R7188:Bltp1	UTSW	3	37,004,162 (GRCm39)	missense	probably benign	0.06
R7212:Bltp1	UTSW	3	37,102,158 (GRCm39)	missense
R7425:Bltp1	UTSW	3	37,037,543 (GRCm39)	missense	probably benign	0.02
R7425:Bltp1	UTSW	3	37,002,490 (GRCm39)	missense	probably benign
R7451:Bltp1	UTSW	3	37,076,956 (GRCm39)	splice site	probably null
R7604:Bltp1	UTSW	3	37,003,992 (GRCm39)	splice site	probably null
R7622:Bltp1	UTSW	3	37,002,562 (GRCm39)	nonsense	probably null
R7671:Bltp1	UTSW	3	36,997,380 (GRCm39)	missense	probably damaging	0.99
R7699:Bltp1	UTSW	3	37,080,303 (GRCm39)	missense	probably benign	0.00
R7699:Bltp1	UTSW	3	37,028,321 (GRCm39)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,028,321 (GRCm39)	missense	possibly damaging	0.67
R7700:Bltp1	UTSW	3	37,080,303 (GRCm39)	missense	probably benign	0.00
R7748:Bltp1	UTSW	3	37,013,484 (GRCm39)	critical splice acceptor site	probably null
R7767:Bltp1	UTSW	3	36,974,436 (GRCm39)	critical splice donor site	probably null
R7787:Bltp1	UTSW	3	36,939,557 (GRCm39)	missense	probably damaging	1.00
R7830:Bltp1	UTSW	3	37,019,081 (GRCm39)	frame shift	probably null
R7849:Bltp1	UTSW	3	37,080,477 (GRCm39)	missense
R7912:Bltp1	UTSW	3	37,061,218 (GRCm39)	missense	probably damaging	0.99
R7914:Bltp1	UTSW	3	37,000,432 (GRCm39)	missense	probably benign	0.13
R7945:Bltp1	UTSW	3	37,020,042 (GRCm39)	missense	probably benign	0.03
R8039:Bltp1	UTSW	3	36,997,363 (GRCm39)	missense	probably benign	0.12
R8101:Bltp1	UTSW	3	37,062,651 (GRCm39)	missense	probably damaging	1.00
R8143:Bltp1	UTSW	3	37,000,657 (GRCm39)	critical splice donor site	probably null
R8145:Bltp1	UTSW	3	37,052,416 (GRCm39)	missense	probably damaging	1.00
R8171:Bltp1	UTSW	3	37,029,862 (GRCm39)	missense	probably benign	0.00
R8210:Bltp1	UTSW	3	37,067,030 (GRCm39)	missense
R8250:Bltp1	UTSW	3	36,971,811 (GRCm39)	missense	probably damaging	0.99
R8369:Bltp1	UTSW	3	37,065,752 (GRCm39)	missense
R8478:Bltp1	UTSW	3	37,087,426 (GRCm39)	missense	possibly damaging	0.74
R8558:Bltp1	UTSW	3	37,102,750 (GRCm39)	missense
R8688:Bltp1	UTSW	3	37,090,066 (GRCm39)	missense
R8724:Bltp1	UTSW	3	36,945,042 (GRCm39)	missense	probably damaging	0.99
R8818:Bltp1	UTSW	3	37,050,697 (GRCm39)	missense	possibly damaging	0.60
R8869:Bltp1	UTSW	3	37,013,007 (GRCm39)	missense	probably damaging	0.99
R8887:Bltp1	UTSW	3	37,087,503 (GRCm39)	missense	possibly damaging	0.95
R8899:Bltp1	UTSW	3	37,042,429 (GRCm39)	missense	probably damaging	1.00
R8907:Bltp1	UTSW	3	37,002,295 (GRCm39)	nonsense	probably null
R8960:Bltp1	UTSW	3	37,067,132 (GRCm39)	missense	probably damaging	1.00
R8990:Bltp1	UTSW	3	36,975,370 (GRCm39)	missense	possibly damaging	0.60
R9021:Bltp1	UTSW	3	37,052,493 (GRCm39)	missense	probably benign	0.00
R9048:Bltp1	UTSW	3	37,065,926 (GRCm39)	missense
R9100:Bltp1	UTSW	3	37,098,907 (GRCm39)	missense
R9166:Bltp1	UTSW	3	37,041,516 (GRCm39)	missense	probably damaging	1.00
R9176:Bltp1	UTSW	3	37,010,852 (GRCm39)	missense	possibly damaging	0.82
R9202:Bltp1	UTSW	3	36,944,970 (GRCm39)	missense	probably benign
R9303:Bltp1	UTSW	3	37,098,969 (GRCm39)	missense
R9305:Bltp1	UTSW	3	37,098,969 (GRCm39)	missense
R9332:Bltp1	UTSW	3	37,104,989 (GRCm39)	missense
R9362:Bltp1	UTSW	3	37,011,162 (GRCm39)	missense	probably benign
R9493:Bltp1	UTSW	3	37,065,885 (GRCm39)	missense
R9534:Bltp1	UTSW	3	37,052,419 (GRCm39)	missense	probably benign	0.01
R9569:Bltp1	UTSW	3	37,066,770 (GRCm39)	missense
R9593:Bltp1	UTSW	3	37,002,090 (GRCm39)	missense	probably damaging	1.00
R9600:Bltp1	UTSW	3	37,095,565 (GRCm39)	nonsense	probably null
R9733:Bltp1	UTSW	3	37,102,732 (GRCm39)	missense
R9751:Bltp1	UTSW	3	37,065,889 (GRCm39)	missense
RF013:Bltp1	UTSW	3	37,104,906 (GRCm39)	critical splice acceptor site	probably benign
RF015:Bltp1	UTSW	3	37,104,897 (GRCm39)	critical splice acceptor site	probably benign
RF021:Bltp1	UTSW	3	37,104,897 (GRCm39)	critical splice acceptor site	probably benign
RF023:Bltp1	UTSW	3	37,104,909 (GRCm39)	critical splice acceptor site	probably benign
RF034:Bltp1	UTSW	3	37,104,909 (GRCm39)	critical splice acceptor site	probably benign
RF035:Bltp1	UTSW	3	37,104,907 (GRCm39)	critical splice acceptor site	probably benign
RF055:Bltp1	UTSW	3	37,104,906 (GRCm39)	critical splice acceptor site	probably benign
X0050:Bltp1	UTSW	3	37,011,277 (GRCm39)	missense	probably damaging	1.00
Z1088:Bltp1	UTSW	3	37,041,716 (GRCm39)	missense	probably damaging	1.00
Z1177:Bltp1	UTSW	3	37,037,589 (GRCm39)	missense	possibly damaging	0.88
Z1177:Bltp1	UTSW	3	36,974,099 (GRCm39)	missense	probably benign
Z1177:Bltp1	UTSW	3	37,090,856 (GRCm39)	missense

Predicted Primers

PCR Primer
(F):5'- ATGTTTTCCTCAGTAAAGCACCC -3'
(R):5'- AATCAGCTGATGGTGTGTAAGG -3'

Sequencing Primer
(F):5'- TTTTCCTCAGTAAAGCACCCTAAATC -3'
(R):5'- GGGAATGAACCAAAACTTCTCCTCTG -3'

Posted On

2014-09-17