Mutagenetix > Incidental Mutation

Incidental Mutation 'R0148:Peg10'

22651

Institutional Source

Beutler Lab

Gene Symbol

Peg10

Ensembl Gene

ENSMUSG00000092035

Gene Name

paternally expressed 10

Synonyms

HB-1, MyEF-3, Mart2, Mar2, MyEF-3 like, MEF3L, Edr

MMRRC Submission

038432-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R0148 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

4747306-4760517 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 4755711 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Serine at position 96 (R96S)

Ref Sequence

ENSEMBL: ENSMUSP00000135076 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166678] [ENSMUST00000176204] [ENSMUST00000176551]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000166678
AA Change: R497S

PolyPhen 2 Score 0.879 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000127306
Gene: ENSMUSG00000092035
AA Change: R497S

Domain	Start	End	E-Value	Type
low complexity region	11	26	N/A	INTRINSIC
low complexity region	34	50	N/A	INTRINSIC
low complexity region	80	107	N/A	INTRINSIC
Pfam:DUF4939	130	220	6.1e-17	PFAM
Pfam:Retrotrans_gag	174	267	2.9e-20	PFAM
low complexity region	334	342	N/A	INTRINSIC
ZnF_C2HC	345	361	3.34e-2	SMART
low complexity region	368	379	N/A	INTRINSIC
low complexity region	541	610	N/A	INTRINSIC
low complexity region	621	660	N/A	INTRINSIC
low complexity region	663	785	N/A	INTRINSIC
Blast:SERPIN	798	910	1e-5	BLAST
low complexity region	923	936	N/A	INTRINSIC
low complexity region	972	998	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000176204

SMART Domains

Protein: ENSMUSP00000134963
Gene: ENSMUSG00000092035

Domain	Start	End	E-Value	Type
low complexity region	11	26	N/A	INTRINSIC
low complexity region	34	50	N/A	INTRINSIC
low complexity region	80	107	N/A	INTRINSIC
Pfam:Retrotrans_gag	174	267	1.3e-20	PFAM
low complexity region	334	342	N/A	INTRINSIC
ZnF_C2HC	345	361	3.34e-2	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000176551
AA Change: R96S

PolyPhen 2 Score 0.879 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000135076
Gene: ENSMUSG00000092035
AA Change: R96S

Domain	Start	End	E-Value	Type
low complexity region	173	242	N/A	INTRINSIC
low complexity region	253	292	N/A	INTRINSIC
low complexity region	295	417	N/A	INTRINSIC
Blast:SERPIN	430	542	6e-6	BLAST
low complexity region	555	568	N/A	INTRINSIC
low complexity region	604	630	N/A	INTRINSIC

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 96.0%
20x: 91.8%

Validation Efficiency

86% (30/35)

MGI Phenotype

FUNCTION: This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation, apoptosis and cancer development. Knockout mice lacking this gene showed early embryonic lethality with placental defects, indicating the importance of this gene in embryonic development. [provided by RefSeq, Oct 2014]
PHENOTYPE: Heterozygous mice with a paternally inherited null allele display embryonic lethality during organogenesis with abnormal placental development. Heterozygous mice with a maternally inherited null allele are viable and fertile. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 76 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2m	T	C	6: 121,662,446		probably null	Het
Agtr1a	T	C	13: 30,381,944	S331P	probably benign	Het
Ank1	T	A	8: 23,123,977	N1545K	probably damaging	Het
Bahcc1	A	T	11: 120,268,404	Q152H	probably damaging	Het
Bend3	T	A	10: 43,511,950	Y780N	probably damaging	Het
Bod1l	G	T	5: 41,818,697	A1758E	possibly damaging	Het
Ctcfl	T	C	2: 173,118,547	D81G	possibly damaging	Het
Ddx39	C	T	8: 83,722,476	R298C	possibly damaging	Het
Dock8	T	C	19: 25,119,459	L577P	probably benign	Het
Drc1	A	T	5: 30,281,489	N13I	possibly damaging	Het
Efl1	T	C	7: 82,671,670	S104P	probably damaging	Het
Eml4	T	A	17: 83,421,652	N85K	probably damaging	Het
Epb41l4a	T	C	18: 33,798,800	T581A	probably damaging	Het
Epha3	T	C	16: 63,612,944	D446G	possibly damaging	Het
Fam209	G	T	2: 172,473,980	G92C	probably damaging	Het
Fbln1	G	A	15: 85,230,826	R193H	probably damaging	Het
Fbxw21	A	G	9: 109,148,017		probably null	Het
Fgf17	C	T	14: 70,638,873	R49Q	probably damaging	Het
Flnb	T	C	14: 7,939,077	S2307P	probably benign	Het
Galr1	A	G	18: 82,405,570	L194P	probably benign	Het
Gar1	T	C	3: 129,829,473	H89R	probably damaging	Het
Gbp4	T	A	5: 105,119,496	Y519F	probably benign	Het
Git1	A	G	11: 77,505,728	T601A	probably benign	Het
Gm10722	T	"C,A"	9: 3,001,405		probably null	Het
Gm5142	C	T	14: 59,178,670	R13H	possibly damaging	Het
Gria2	A	C	3: 80,707,731	W481G	probably damaging	Het
Homer2	T	C	7: 81,624,278	T57A	probably benign	Het
Hpse2	A	C	19: 42,931,660		probably null	Het
Hspb7	T	C	4: 141,423,991	I148T	probably damaging	Het
Htr1d	C	A	4: 136,443,477	T339K	probably damaging	Het
Il4ra	T	A	7: 125,575,537	C306S	probably damaging	Het
Kansl3	A	T	1: 36,353,816	C225S	probably damaging	Het
Lama3	G	A	18: 12,448,272	C596Y	probably damaging	Het
Lama5	T	C	2: 180,190,406	H1714R	probably benign	Het
March6	C	T	15: 31,490,612	V293M	probably damaging	Het
Med12l	A	G	3: 59,037,654	D100G	probably damaging	Het
Mettl14	G	A	3: 123,371,394	T316I	probably damaging	Het
Mmp15	A	T	8: 95,372,317	N591Y	probably benign	Het
Mrpl53	T	C	6: 83,109,537	L74P	probably damaging	Het
Mvp	C	T	7: 126,989,865	V577M	probably damaging	Het
Neb	T	C	2: 52,249,376	K140E	probably damaging	Het
Nfya	A	G	17: 48,398,998	V48A	possibly damaging	Het
Ngf	G	T	3: 102,509,803		probably benign	Het
Nipsnap3b	C	T	4: 53,017,088	A104V	possibly damaging	Het
Nlrp14	A	G	7: 107,182,721	Y375C	probably benign	Het
Nod1	A	G	6: 54,938,217	Y764H	probably damaging	Het
Olfr225	G	A	11: 59,613,494	V177M	probably damaging	Het
Olfr270	A	T	4: 52,971,232	I204F	probably benign	Het
Olfr873	T	G	9: 20,301,091	M297R	probably damaging	Het
Pcdhb19	A	T	18: 37,497,182	Q10L	probably benign	Het
Pdcl	T	C	2: 37,352,130	I203V	probably benign	Het
Pknox1	T	A	17: 31,604,790	N379K	probably benign	Het
Prodh	T	G	16: 18,077,813	Q360P	probably damaging	Het
Raf1	C	T	6: 115,632,973	G202S	probably benign	Het
Rgs11	T	A	17: 26,207,459		probably null	Het
Rilp	A	T	11: 75,510,233	H29L	probably damaging	Het
Rtel1	T	C	2: 181,321,046	C31R	probably damaging	Het
Rubcnl	T	A	14: 75,042,458	I427K	probably damaging	Het
Ryr1	C	A	7: 29,052,035	R3706L	probably damaging	Het
Ryr2	T	C	13: 11,714,548	D2396G	probably damaging	Het
Slc45a2	T	C	15: 11,025,868	S435P	probably damaging	Het
Spata17	A	G	1: 187,112,601	V111A	probably damaging	Het
Svep1	C	T	4: 58,116,608	D881N	possibly damaging	Het
Sypl2	T	A	3: 108,219,095	N67I	possibly damaging	Het
Tenm3	T	C	8: 48,236,720	Y1944C	probably damaging	Het
Tep1	A	T	14: 50,824,789	D2535E	possibly damaging	Het
Tkt	T	A	14: 30,572,220	I529N	probably damaging	Het
Trp53i11	T	G	2: 93,197,735	V39G	probably damaging	Het
Trpm2	C	T	10: 77,925,825	G997D	probably damaging	Het
Usp3	A	G	9: 66,540,167	V219A	possibly damaging	Het
Usp4	T	A	9: 108,391,671		probably null	Het
Wdfy3	A	G	5: 101,917,411	V1297A	probably benign	Het
Wdr46	T	A	17: 33,941,023	F70I	probably benign	Het
Xkr6	T	C	14: 63,819,549	V303A	unknown	Het
Zdbf2	C	T	1: 63,304,006	Q515*	probably null	Het
Zfhx2	A	G	14: 55,072,897	Y731H	possibly damaging	Het

Other mutations in Peg10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02029:Peg10	APN	6	4754473	utr 5 prime	probably benign
IGL03063:Peg10	APN	6	4756647	utr 3 prime	probably benign
piaggio	UTSW	6	4756427	utr 3 prime	probably benign
PIT4480001:Peg10	UTSW	6	4756560	missense	unknown
R0090:Peg10	UTSW	6	4756063	utr 3 prime	probably benign
R0650:Peg10	UTSW	6	4756475	small insertion	probably benign
R0698:Peg10	UTSW	6	4756835	utr 3 prime	probably benign
R1600:Peg10	UTSW	6	4757080	utr 3 prime	probably benign
R1842:Peg10	UTSW	6	4756381	utr 3 prime	probably benign
R1930:Peg10	UTSW	6	4755778	missense	probably damaging	0.99
R1931:Peg10	UTSW	6	4755778	missense	probably damaging	0.99
R2162:Peg10	UTSW	6	4755914	utr 3 prime	probably benign
R2215:Peg10	UTSW	6	4756918	utr 3 prime	probably benign
R2339:Peg10	UTSW	6	4756102	utr 3 prime	probably benign
R2847:Peg10	UTSW	6	4756912	utr 3 prime	probably benign
R2848:Peg10	UTSW	6	4756912	utr 3 prime	probably benign
R3000:Peg10	UTSW	6	4754276	utr 5 prime	probably benign
R3056:Peg10	UTSW	6	4755029	missense	possibly damaging	0.66
R4051:Peg10	UTSW	6	4754534	missense	probably benign	0.00
R4059:Peg10	UTSW	6	4756427	utr 3 prime	probably benign
R4296:Peg10	UTSW	6	4756472	small insertion	probably benign
R4626:Peg10	UTSW	6	4756460	small insertion	probably benign
R4634:Peg10	UTSW	6	4756452	small insertion	probably benign
R4679:Peg10	UTSW	6	4756452	small insertion	probably benign
R4834:Peg10	UTSW	6	4754294	utr 5 prime	probably benign
R4982:Peg10	UTSW	6	4756451	small insertion	probably benign
R4983:Peg10	UTSW	6	4756451	small insertion	probably benign
R4996:Peg10	UTSW	6	4756454	small insertion	probably benign
R4997:Peg10	UTSW	6	4756457	small insertion	probably benign
R5015:Peg10	UTSW	6	4756453	small insertion	probably benign
R5085:Peg10	UTSW	6	4755864	utr 3 prime	probably benign
R5091:Peg10	UTSW	6	4754511	missense	probably benign	0.01
R5231:Peg10	UTSW	6	4756939	utr 3 prime	probably benign
R5278:Peg10	UTSW	6	4756442	small deletion	probably benign
R5364:Peg10	UTSW	6	4756128	utr 3 prime	probably benign
R5397:Peg10	UTSW	6	4756453	small insertion	probably benign
R5485:Peg10	UTSW	6	4755565	missense	probably benign	0.09
R5573:Peg10	UTSW	6	4755913	utr 3 prime	probably benign
R5710:Peg10	UTSW	6	4756350	small insertion	probably benign
R5710:Peg10	UTSW	6	4756351	small insertion	probably benign
R5736:Peg10	UTSW	6	4754423	missense	probably benign	0.00
R5865:Peg10	UTSW	6	4754375	missense	probably damaging	0.98
R6056:Peg10	UTSW	6	4756449	small insertion	probably benign
R6116:Peg10	UTSW	6	4756351	small insertion	probably benign
R6129:Peg10	UTSW	6	4756449	small insertion	probably benign
R6147:Peg10	UTSW	6	4754499	start gained	probably benign
R6171:Peg10	UTSW	6	4756449	small insertion	probably benign
R6194:Peg10	UTSW	6	4756351	small insertion	probably benign
R6197:Peg10	UTSW	6	4756452	small insertion	probably benign
R6207:Peg10	UTSW	6	4756449	small insertion	probably benign
R6215:Peg10	UTSW	6	4756452	small insertion	probably benign
R6276:Peg10	UTSW	6	4756449	small insertion	probably benign
R6281:Peg10	UTSW	6	4756449	small insertion	probably benign
R6287:Peg10	UTSW	6	4756451	small insertion	probably benign
R6302:Peg10	UTSW	6	4756449	small insertion	probably benign
R6393:Peg10	UTSW	6	4756452	small insertion	probably benign
R6394:Peg10	UTSW	6	4756451	small insertion	probably benign
R6405:Peg10	UTSW	6	4756453	small insertion	probably benign
R6421:Peg10	UTSW	6	4756449	small insertion	probably benign
R6486:Peg10	UTSW	6	4756449	small insertion	probably benign
R6538:Peg10	UTSW	6	4756449	small insertion	probably benign
R6668:Peg10	UTSW	6	4754502	missense	probably benign	0.01
R6679:Peg10	UTSW	6	4754276	utr 5 prime	probably benign
R6685:Peg10	UTSW	6	4754738	missense	probably damaging	1.00
R6702:Peg10	UTSW	6	4756452	small insertion	probably benign
R6706:Peg10	UTSW	6	4756452	small insertion	probably benign
R6747:Peg10	UTSW	6	4757137	utr 3 prime	probably benign
R6775:Peg10	UTSW	6	4756452	small insertion	probably benign
R6811:Peg10	UTSW	6	4756451	small insertion	probably benign
R6823:Peg10	UTSW	6	4756431	small deletion	probably benign
R6826:Peg10	UTSW	6	4756353	small insertion	probably benign
R6847:Peg10	UTSW	6	4754279	utr 5 prime	probably benign
R6861:Peg10	UTSW	6	4756350	small insertion	probably benign
R6861:Peg10	UTSW	6	4756351	small insertion	probably benign
R6876:Peg10	UTSW	6	4756451	small insertion	probably benign
R6891:Peg10	UTSW	6	4756449	small insertion	probably benign
R6911:Peg10	UTSW	6	4756452	small insertion	probably benign
R6973:Peg10	UTSW	6	4756431	small deletion	probably benign
R6990:Peg10	UTSW	6	4756451	small insertion	probably benign
R6998:Peg10	UTSW	6	4756398	small deletion	probably benign
R7070:Peg10	UTSW	6	4756454	small insertion	probably benign
R7120:Peg10	UTSW	6	4756398	small deletion	probably benign
R7132:Peg10	UTSW	6	4756398	small deletion	probably benign
R7140:Peg10	UTSW	6	4756452	small insertion	probably benign
R7189:Peg10	UTSW	6	4756431	small deletion	probably benign
R7208:Peg10	UTSW	6	4756398	small deletion	probably benign
R7256:Peg10	UTSW	6	4756398	small deletion	probably benign
R7260:Peg10	UTSW	6	4756398	small deletion	probably benign
R7261:Peg10	UTSW	6	4756591	missense	unknown
R7401:Peg10	UTSW	6	4756452	small insertion	probably benign
R7409:Peg10	UTSW	6	4756398	small deletion	probably benign
R7439:Peg10	UTSW	6	4756453	small insertion	probably benign
R7475:Peg10	UTSW	6	4756398	small deletion	probably benign
R7483:Peg10	UTSW	6	4756451	small insertion	probably benign
R7502:Peg10	UTSW	6	4756398	small deletion	probably benign
R7515:Peg10	UTSW	6	4756452	small insertion	probably benign
R7520:Peg10	UTSW	6	4756796	missense	unknown
R7544:Peg10	UTSW	6	4756427	frame shift	probably null
R7571:Peg10	UTSW	6	4756082	missense	unknown
R7581:Peg10	UTSW	6	4756452	small insertion	probably benign
R7635:Peg10	UTSW	6	4754938	missense	probably damaging	0.99
R7677:Peg10	UTSW	6	4756398	small deletion	probably benign
R7697:Peg10	UTSW	6	4756453	small insertion	probably benign
R7710:Peg10	UTSW	6	4756452	small insertion	probably benign
R7803:Peg10	UTSW	6	4756431	small deletion	probably benign
R7816:Peg10	UTSW	6	4756453	small insertion	probably benign
R7820:Peg10	UTSW	6	4756398	small deletion	probably benign
R7827:Peg10	UTSW	6	4756452	small insertion	probably benign
R7861:Peg10	UTSW	6	4756431	small deletion	probably benign
R7881:Peg10	UTSW	6	4756454	small insertion	probably benign
R7904:Peg10	UTSW	6	4756452	small insertion	probably benign
R7915:Peg10	UTSW	6	4756451	small insertion	probably benign
R7916:Peg10	UTSW	6	4756451	small insertion	probably benign
R7963:Peg10	UTSW	6	4756452	small insertion	probably benign
R8016:Peg10	UTSW	6	4756451	small insertion	probably benign
R8037:Peg10	UTSW	6	4756398	small deletion	probably benign
R8062:Peg10	UTSW	6	4756398	small deletion	probably benign
R8081:Peg10	UTSW	6	4756452	small insertion	probably benign
R8113:Peg10	UTSW	6	4756451	small insertion	probably benign
R8115:Peg10	UTSW	6	4756707	missense	unknown
R8140:Peg10	UTSW	6	4756113	missense	unknown
R8178:Peg10	UTSW	6	4756452	small insertion	probably benign
R8233:Peg10	UTSW	6	4756453	small insertion	probably benign
R8239:Peg10	UTSW	6	4756452	small insertion	probably benign
R8281:Peg10	UTSW	6	4756431	small deletion	probably benign
R8310:Peg10	UTSW	6	4756454	small insertion	probably benign
R8312:Peg10	UTSW	6	4756452	small insertion	probably benign
R8330:Peg10	UTSW	6	4756452	small insertion	probably benign
R8338:Peg10	UTSW	6	4756398	small deletion	probably benign
R8354:Peg10	UTSW	6	4756452	small insertion	probably benign
R8387:Peg10	UTSW	6	4756452	small insertion	probably benign
R8390:Peg10	UTSW	6	4756451	small insertion	probably benign
R8408:Peg10	UTSW	6	4756453	small insertion	probably benign
R8415:Peg10	UTSW	6	4756451	small insertion	probably benign
R8439:Peg10	UTSW	6	4755462	missense	possibly damaging	0.58
R8444:Peg10	UTSW	6	4756398	small deletion	probably benign
R8463:Peg10	UTSW	6	4756453	small insertion	probably benign
R8477:Peg10	UTSW	6	4756453	small insertion	probably benign
R8507:Peg10	UTSW	6	4756453	small insertion	probably benign
R8552:Peg10	UTSW	6	4756452	small insertion	probably benign
R8678:Peg10	UTSW	6	4756431	small deletion	probably benign
R8699:Peg10	UTSW	6	4756451	small insertion	probably benign
R8700:Peg10	UTSW	6	4756451	small insertion	probably benign
R8705:Peg10	UTSW	6	4756398	small deletion	probably benign
R8765:Peg10	UTSW	6	4754492	missense	unknown
R8824:Peg10	UTSW	6	4756451	small insertion	probably benign
R8859:Peg10	UTSW	6	4756451	small insertion	probably benign
R8870:Peg10	UTSW	6	4754825	missense	probably damaging	0.99
R8909:Peg10	UTSW	6	4756451	small insertion	probably benign
R8918:Peg10	UTSW	6	4756398	small deletion	probably benign
R8924:Peg10	UTSW	6	4756398	small deletion	probably benign
R8925:Peg10	UTSW	6	4756452	small insertion	probably benign
R8930:Peg10	UTSW	6	4756449	small insertion	probably benign
R8950:Peg10	UTSW	6	4756452	small insertion	probably benign
R8960:Peg10	UTSW	6	4756449	small insertion	probably benign
R8975:Peg10	UTSW	6	4756452	small insertion	probably benign
R8988:Peg10	UTSW	6	4756398	small deletion	probably benign
R9046:Peg10	UTSW	6	4756452	small insertion	probably benign
R9068:Peg10	UTSW	6	4756451	small insertion	probably benign
R9074:Peg10	UTSW	6	4756451	small insertion	probably benign
R9088:Peg10	UTSW	6	4756453	small insertion	probably benign
R9094:Peg10	UTSW	6	4756449	small insertion	probably benign
R9114:Peg10	UTSW	6	4756452	small insertion	probably benign
R9116:Peg10	UTSW	6	4756452	small insertion	probably benign
R9135:Peg10	UTSW	6	4756453	small insertion	probably benign
R9137:Peg10	UTSW	6	4756398	small deletion	probably benign
R9139:Peg10	UTSW	6	4756449	small insertion	probably benign
R9139:Peg10	UTSW	6	4757128	missense	unknown
R9171:Peg10	UTSW	6	4756452	small insertion	probably benign
R9173:Peg10	UTSW	6	4756451	small insertion	probably benign
R9213:Peg10	UTSW	6	4756451	small insertion	probably benign
R9216:Peg10	UTSW	6	4756452	small insertion	probably benign
R9229:Peg10	UTSW	6	4756398	small deletion	probably benign
R9233:Peg10	UTSW	6	4756398	small deletion	probably benign
R9283:Peg10	UTSW	6	4756452	small insertion	probably benign
R9328:Peg10	UTSW	6	4756398	small deletion	probably benign
R9367:Peg10	UTSW	6	4756398	small deletion	probably benign
R9369:Peg10	UTSW	6	4756452	small insertion	probably benign
R9405:Peg10	UTSW	6	4756398	small deletion	probably benign
R9410:Peg10	UTSW	6	4756452	small insertion	probably benign
R9412:Peg10	UTSW	6	4756453	small insertion	probably benign
R9421:Peg10	UTSW	6	4756398	small deletion	probably benign
R9437:Peg10	UTSW	6	4756451	small insertion	probably benign
R9440:Peg10	UTSW	6	4756451	small insertion	probably benign
R9460:Peg10	UTSW	6	4756452	small insertion	probably benign
R9492:Peg10	UTSW	6	4756398	small deletion	probably benign
R9495:Peg10	UTSW	6	4756451	small insertion	probably benign
R9500:Peg10	UTSW	6	4756871	missense	unknown
R9511:Peg10	UTSW	6	4756451	small insertion	probably benign
R9515:Peg10	UTSW	6	4756452	small insertion	probably benign
R9576:Peg10	UTSW	6	4756398	small deletion	probably benign
R9610:Peg10	UTSW	6	4756452	small insertion	probably benign
R9611:Peg10	UTSW	6	4756452	small insertion	probably benign
R9611:Peg10	UTSW	6	4756453	small insertion	probably benign
R9614:Peg10	UTSW	6	4756451	small insertion	probably benign
R9619:Peg10	UTSW	6	4755316	missense	probably benign	0.02
R9646:Peg10	UTSW	6	4756452	small insertion	probably benign
R9655:Peg10	UTSW	6	4756398	small deletion	probably benign
R9673:Peg10	UTSW	6	4756452	small insertion	probably benign
R9675:Peg10	UTSW	6	4756398	small deletion	probably benign
R9696:Peg10	UTSW	6	4756431	small deletion	probably benign
R9749:Peg10	UTSW	6	4756398	small deletion	probably benign
R9756:Peg10	UTSW	6	4756452	small insertion	probably benign
X0065:Peg10	UTSW	6	4756515	utr 3 prime	probably benign
Z1176:Peg10	UTSW	6	4756451	small insertion	probably benign

Predicted Primers

PCR Primer
(F):5'- TCAGCACCTGCAAGTGATGCTC -3'
(R):5'- TGGACATGCGGATGCACATGATG -3'

Sequencing Primer
(F):5'- GCAAGTGATGCTCCAGATTC -3'
(R):5'- gcggatgcaCATGATGAAGTAG -3'

Posted On

2013-04-16