Incidental Mutation 'R2066:Phldb2'
| ID |
226706 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phldb2
|
| Ensembl Gene |
ENSMUSG00000033149 |
| Gene Name |
pleckstrin homology like domain, family B, member 2 |
| Synonyms |
LL5b, LL5beta, C820004H04Rik |
| MMRRC Submission |
040071-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2066 (G1)
|
| Quality Score |
195 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
45746243-45953598 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 45770758 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 970
(L970Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123284
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036355]
[ENSMUST00000076333]
[ENSMUST00000134802]
|
| AlphaFold |
Q8K1N2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000036355
AA Change: L925Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000046496
Gene: ENSMUSG00000033149
AA Change: L925Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
coiled coil region
|
1027 |
1097 |
N/A |
INTRINSIC |
|
PH
|
1140 |
1244 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076333
AA Change: L978Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000075672
Gene: ENSMUSG00000033149
AA Change: L978Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
901 |
913 |
N/A |
INTRINSIC |
|
coiled coil region
|
1080 |
1150 |
N/A |
INTRINSIC |
|
PH
|
1193 |
1297 |
6.45e-17 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000131003
AA Change: L240Q
|
| SMART Domains |
Protein: ENSMUSP00000119718
Gene: ENSMUSG00000033149
AA Change: L240Q
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
55 |
N/A |
INTRINSIC |
|
coiled coil region
|
87 |
163 |
N/A |
INTRINSIC |
|
coiled coil region
|
342 |
412 |
N/A |
INTRINSIC |
|
PH
|
456 |
560 |
6.45e-17 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133111
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000134802
AA Change: L970Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000123284
Gene: ENSMUSG00000033149
AA Change: L970Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
312 |
328 |
N/A |
INTRINSIC |
|
low complexity region
|
471 |
492 |
N/A |
INTRINSIC |
|
coiled coil region
|
625 |
737 |
N/A |
INTRINSIC |
|
coiled coil region
|
769 |
845 |
N/A |
INTRINSIC |
|
coiled coil region
|
1072 |
1131 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151300
|
| Meta Mutation Damage Score |
0.2491 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.6%
|
| Validation Efficiency |
100% (79/79) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933436I01Rik |
T |
A |
X: 67,920,702 (GRCm38) |
I184L |
probably benign |
Het |
| 9530002B09Rik |
T |
A |
4: 122,689,322 (GRCm38) |
|
probably benign |
Het |
| Acadl |
C |
T |
1: 66,841,746 (GRCm38) |
|
probably null |
Het |
| Acss1 |
G |
A |
2: 150,668,131 (GRCm38) |
Q23* |
probably null |
Het |
| Afap1l1 |
A |
T |
18: 61,739,122 (GRCm38) |
|
probably null |
Het |
| Akt3 |
A |
G |
1: 177,102,985 (GRCm38) |
S136P |
possibly damaging |
Het |
| Amy2a1 |
T |
C |
3: 113,530,568 (GRCm38) |
I108V |
probably benign |
Het |
| Ano5 |
T |
G |
7: 51,585,386 (GRCm38) |
L639R |
probably damaging |
Het |
| Arhgap26 |
T |
C |
18: 39,306,728 (GRCm38) |
S71P |
probably damaging |
Het |
| B3gnt2 |
A |
G |
11: 22,836,735 (GRCm38) |
L151P |
probably damaging |
Het |
| Bach1 |
A |
T |
16: 87,729,625 (GRCm38) |
K658N |
probably damaging |
Het |
| Bdnf |
C |
A |
2: 109,723,902 (GRCm38) |
T207K |
probably damaging |
Het |
| Bod1l |
G |
T |
5: 41,805,156 (GRCm38) |
T2746K |
probably damaging |
Het |
| Brwd1 |
A |
G |
16: 96,046,465 (GRCm38) |
S652P |
probably benign |
Het |
| Ccnt1 |
A |
T |
15: 98,551,942 (GRCm38) |
H156Q |
probably benign |
Het |
| Clasp2 |
T |
A |
9: 113,906,157 (GRCm38) |
I1021N |
possibly damaging |
Het |
| Cnep1r1 |
G |
T |
8: 88,118,817 (GRCm38) |
|
probably benign |
Het |
| Cntn6 |
C |
T |
6: 104,861,822 (GRCm38) |
R946* |
probably null |
Het |
| Dnaaf3 |
T |
C |
7: 4,523,799 (GRCm38) |
I426M |
possibly damaging |
Het |
| Dnajc13 |
A |
T |
9: 104,221,441 (GRCm38) |
I471N |
probably benign |
Het |
| Ehd1 |
T |
C |
19: 6,298,078 (GRCm38) |
L362P |
probably benign |
Het |
| Emx2 |
A |
G |
19: 59,461,698 (GRCm38) |
N149S |
probably benign |
Het |
| Fbln7 |
G |
T |
2: 128,877,466 (GRCm38) |
R61L |
probably damaging |
Het |
| Fgb |
C |
A |
3: 83,049,689 (GRCm38) |
D25Y |
probably benign |
Het |
| Filip1 |
A |
G |
9: 79,820,216 (GRCm38) |
S374P |
probably damaging |
Het |
| Fry |
T |
A |
5: 150,370,119 (GRCm38) |
|
probably benign |
Het |
| Gm12695 |
T |
C |
4: 96,769,726 (GRCm38) |
T69A |
probably benign |
Het |
| Gm2959 |
A |
G |
14: 42,413,701 (GRCm38) |
|
noncoding transcript |
Het |
| Gm9912 |
T |
C |
3: 149,185,159 (GRCm38) |
T113A |
unknown |
Het |
| Hdlbp |
A |
G |
1: 93,421,880 (GRCm38) |
|
probably benign |
Het |
| Hunk |
G |
A |
16: 90,481,245 (GRCm38) |
|
probably null |
Het |
| Ifnb1 |
T |
A |
4: 88,522,759 (GRCm38) |
I6F |
possibly damaging |
Het |
| Il2rg |
A |
G |
X: 101,267,810 (GRCm38) |
L57P |
possibly damaging |
Het |
| Ints1 |
A |
G |
5: 139,767,496 (GRCm38) |
V720A |
probably benign |
Het |
| Invs |
T |
A |
4: 48,396,287 (GRCm38) |
L320Q |
probably damaging |
Het |
| Jpt2 |
G |
A |
17: 24,948,739 (GRCm38) |
Q79* |
probably null |
Het |
| Lingo2 |
A |
G |
4: 35,709,179 (GRCm38) |
L267P |
probably benign |
Het |
| Lonp2 |
A |
G |
8: 86,665,775 (GRCm38) |
T490A |
probably damaging |
Het |
| Meiob |
G |
T |
17: 24,818,316 (GRCm38) |
R56L |
probably damaging |
Het |
| Mindy3 |
A |
T |
2: 12,419,249 (GRCm38) |
S2T |
probably damaging |
Het |
| Mrm3 |
A |
T |
11: 76,250,321 (GRCm38) |
D385V |
probably damaging |
Het |
| Mrto4 |
T |
C |
4: 139,349,023 (GRCm38) |
K86E |
probably benign |
Het |
| Naf1 |
A |
G |
8: 66,887,780 (GRCm38) |
D414G |
probably damaging |
Het |
| Nav1 |
C |
T |
1: 135,449,004 (GRCm38) |
R1694Q |
probably damaging |
Het |
| Nbea |
A |
G |
3: 55,968,146 (GRCm38) |
V1701A |
probably damaging |
Het |
| Nipal4 |
T |
G |
11: 46,156,795 (GRCm38) |
D104A |
probably damaging |
Het |
| Npas4 |
A |
G |
19: 4,987,414 (GRCm38) |
V284A |
probably damaging |
Het |
| Nup133 |
C |
A |
8: 123,914,575 (GRCm38) |
D869Y |
probably damaging |
Het |
| Obscn |
G |
A |
11: 59,135,732 (GRCm38) |
A215V |
possibly damaging |
Het |
| Olfr1218 |
A |
G |
2: 89,054,899 (GRCm38) |
Y176H |
probably damaging |
Het |
| Olfr870 |
G |
T |
9: 20,171,554 (GRCm38) |
Q6K |
probably benign |
Het |
| Olfr938 |
T |
C |
9: 39,078,214 (GRCm38) |
Y177C |
probably damaging |
Het |
| Pgs1 |
G |
A |
11: 118,014,570 (GRCm38) |
|
probably benign |
Het |
| Phc2 |
T |
C |
4: 128,747,136 (GRCm38) |
F672S |
probably damaging |
Het |
| Plxnb3 |
T |
A |
X: 73,771,751 (GRCm38) |
Y1845* |
probably null |
Het |
| Ppip5k1 |
A |
G |
2: 121,342,871 (GRCm38) |
|
probably benign |
Het |
| Prune2 |
A |
G |
19: 17,120,678 (GRCm38) |
D1182G |
possibly damaging |
Het |
| Psg25 |
G |
A |
7: 18,529,562 (GRCm38) |
T112I |
probably damaging |
Het |
| Sec61g |
T |
C |
11: 16,508,124 (GRCm38) |
T24A |
probably benign |
Het |
| Skint1 |
T |
A |
4: 112,025,533 (GRCm38) |
V258D |
probably benign |
Het |
| Sorbs1 |
T |
C |
19: 40,365,028 (GRCm38) |
|
probably null |
Het |
| Sox2 |
C |
A |
3: 34,651,307 (GRCm38) |
Q298K |
possibly damaging |
Het |
| Spatc1 |
T |
A |
15: 76,283,537 (GRCm38) |
|
probably null |
Het |
| Szt2 |
T |
C |
4: 118,373,980 (GRCm38) |
M2529V |
unknown |
Het |
| Thrap3 |
T |
C |
4: 126,175,396 (GRCm38) |
Y654C |
possibly damaging |
Het |
| Tpp2 |
T |
G |
1: 43,978,438 (GRCm38) |
I734S |
possibly damaging |
Het |
| Troap |
T |
C |
15: 99,082,463 (GRCm38) |
L508P |
probably benign |
Het |
| Ttc28 |
C |
A |
5: 111,225,933 (GRCm38) |
F1078L |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,714,373 (GRCm38) |
N32795S |
probably damaging |
Het |
| Ubap2 |
C |
T |
4: 41,199,872 (GRCm38) |
A752T |
probably benign |
Het |
| Ugt2b36 |
T |
C |
5: 87,092,241 (GRCm38) |
E95G |
probably benign |
Het |
| Vmn1r55 |
A |
G |
7: 5,147,049 (GRCm38) |
V125A |
possibly damaging |
Het |
| Vstm2a |
A |
T |
11: 16,261,483 (GRCm38) |
I98F |
probably benign |
Het |
| Zdhhc13 |
T |
A |
7: 48,816,427 (GRCm38) |
V284D |
probably benign |
Het |
| Zfp668 |
C |
A |
7: 127,867,031 (GRCm38) |
R327L |
probably damaging |
Het |
| Zgrf1 |
T |
C |
3: 127,613,350 (GRCm38) |
C1589R |
probably damaging |
Het |
|
| Other mutations in Phldb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00321:Phldb2
|
APN |
16 |
45,772,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00485:Phldb2
|
APN |
16 |
45,757,188 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
IGL00544:Phldb2
|
APN |
16 |
45,825,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00547:Phldb2
|
APN |
16 |
45,825,535 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL00835:Phldb2
|
APN |
16 |
45,751,456 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00987:Phldb2
|
APN |
16 |
45,763,102 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
IGL01102:Phldb2
|
APN |
16 |
45,825,060 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01530:Phldb2
|
APN |
16 |
45,802,729 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01549:Phldb2
|
APN |
16 |
45,774,318 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01712:Phldb2
|
APN |
16 |
45,751,429 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01755:Phldb2
|
APN |
16 |
45,825,582 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01823:Phldb2
|
APN |
16 |
45,825,144 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02353:Phldb2
|
APN |
16 |
45,748,779 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02360:Phldb2
|
APN |
16 |
45,748,779 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02716:Phldb2
|
APN |
16 |
45,801,590 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0139:Phldb2
|
UTSW |
16 |
45,770,666 (GRCm38) |
splice site |
probably benign |
|
|
R0312:Phldb2
|
UTSW |
16 |
45,789,047 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0379:Phldb2
|
UTSW |
16 |
45,781,451 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0535:Phldb2
|
UTSW |
16 |
45,757,127 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1387:Phldb2
|
UTSW |
16 |
45,825,994 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R1444:Phldb2
|
UTSW |
16 |
45,757,253 (GRCm38) |
splice site |
probably benign |
|
|
R1487:Phldb2
|
UTSW |
16 |
45,789,024 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1501:Phldb2
|
UTSW |
16 |
45,777,783 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1605:Phldb2
|
UTSW |
16 |
45,770,779 (GRCm38) |
splice site |
probably benign |
|
|
R1716:Phldb2
|
UTSW |
16 |
45,775,050 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1732:Phldb2
|
UTSW |
16 |
45,757,166 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1779:Phldb2
|
UTSW |
16 |
45,801,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1824:Phldb2
|
UTSW |
16 |
45,826,011 (GRCm38) |
missense |
probably benign |
0.14 |
|
R2001:Phldb2
|
UTSW |
16 |
45,774,195 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R2122:Phldb2
|
UTSW |
16 |
45,762,941 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2448:Phldb2
|
UTSW |
16 |
45,825,363 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2932:Phldb2
|
UTSW |
16 |
45,748,785 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3076:Phldb2
|
UTSW |
16 |
45,825,010 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3078:Phldb2
|
UTSW |
16 |
45,825,010 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3779:Phldb2
|
UTSW |
16 |
45,748,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3914:Phldb2
|
UTSW |
16 |
45,757,163 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4536:Phldb2
|
UTSW |
16 |
45,770,681 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4568:Phldb2
|
UTSW |
16 |
45,777,718 (GRCm38) |
nonsense |
probably null |
|
|
R4798:Phldb2
|
UTSW |
16 |
45,825,874 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4853:Phldb2
|
UTSW |
16 |
45,802,716 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4906:Phldb2
|
UTSW |
16 |
45,751,395 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4984:Phldb2
|
UTSW |
16 |
45,825,633 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5078:Phldb2
|
UTSW |
16 |
45,777,742 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5137:Phldb2
|
UTSW |
16 |
45,808,258 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5237:Phldb2
|
UTSW |
16 |
45,747,886 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5410:Phldb2
|
UTSW |
16 |
45,825,612 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R5825:Phldb2
|
UTSW |
16 |
45,763,097 (GRCm38) |
missense |
probably benign |
0.11 |
|
R5874:Phldb2
|
UTSW |
16 |
45,801,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5907:Phldb2
|
UTSW |
16 |
45,825,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6332:Phldb2
|
UTSW |
16 |
45,774,246 (GRCm38) |
missense |
probably benign |
|
|
R6354:Phldb2
|
UTSW |
16 |
45,825,114 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6355:Phldb2
|
UTSW |
16 |
45,825,338 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6383:Phldb2
|
UTSW |
16 |
45,748,750 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6463:Phldb2
|
UTSW |
16 |
45,774,993 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6513:Phldb2
|
UTSW |
16 |
45,747,877 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R6593:Phldb2
|
UTSW |
16 |
45,825,427 (GRCm38) |
nonsense |
probably null |
|
|
R6756:Phldb2
|
UTSW |
16 |
45,808,320 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6810:Phldb2
|
UTSW |
16 |
45,748,725 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6897:Phldb2
|
UTSW |
16 |
45,777,775 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7010:Phldb2
|
UTSW |
16 |
45,751,505 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7142:Phldb2
|
UTSW |
16 |
45,757,176 (GRCm38) |
nonsense |
probably null |
|
|
R7149:Phldb2
|
UTSW |
16 |
45,751,532 (GRCm38) |
nonsense |
probably null |
|
|
R7249:Phldb2
|
UTSW |
16 |
45,801,614 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7300:Phldb2
|
UTSW |
16 |
45,825,562 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7328:Phldb2
|
UTSW |
16 |
45,758,209 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7515:Phldb2
|
UTSW |
16 |
45,774,240 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R7840:Phldb2
|
UTSW |
16 |
45,751,364 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7988:Phldb2
|
UTSW |
16 |
45,825,571 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8159:Phldb2
|
UTSW |
16 |
45,860,384 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R8353:Phldb2
|
UTSW |
16 |
45,825,022 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8453:Phldb2
|
UTSW |
16 |
45,825,022 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8969:Phldb2
|
UTSW |
16 |
45,772,133 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9058:Phldb2
|
UTSW |
16 |
45,772,241 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R9106:Phldb2
|
UTSW |
16 |
45,860,394 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9278:Phldb2
|
UTSW |
16 |
45,825,945 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9324:Phldb2
|
UTSW |
16 |
45,775,074 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9563:Phldb2
|
UTSW |
16 |
45,824,884 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R9626:Phldb2
|
UTSW |
16 |
45,772,184 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R9712:Phldb2
|
UTSW |
16 |
45,774,977 (GRCm38) |
missense |
probably benign |
0.27 |
|
R9718:Phldb2
|
UTSW |
16 |
45,781,393 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
RF008:Phldb2
|
UTSW |
16 |
45,762,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,953,508 (GRCm38) |
unclassified |
probably benign |
|
|
Z1176:Phldb2
|
UTSW |
16 |
45,825,827 (GRCm38) |
missense |
probably benign |
0.04 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,825,826 (GRCm38) |
missense |
probably benign |
0.43 |
|
Z1190:Phldb2
|
UTSW |
16 |
45,825,334 (GRCm38) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGGACATGGGTTGATCTTCCC -3'
(R):5'- AGCAGAGCTTCTTGGGAGAG -3'
Sequencing Primer
(F):5'- ATGGGTTGATCTTCCCTCCCAAC -3'
(R):5'- CTTGGGAGAGATGGTGAGTAATTAGC -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation