Incidental Mutation 'R2067:Zgrf1'
| ID |
226738 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zgrf1
|
| Ensembl Gene |
ENSMUSG00000051278 |
| Gene Name |
zinc finger, GRF-type containing 1 |
| Synonyms |
4930422G04Rik |
| MMRRC Submission |
040072-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.066)
|
| Stock # |
R2067 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
127553489-127618023 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 127613350 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Arginine
at position 1589
(C1589R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143761
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043108]
[ENSMUST00000196141]
[ENSMUST00000196341]
[ENSMUST00000199888]
[ENSMUST00000200490]
|
| AlphaFold |
Q0VGT4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043108
AA Change: C1589R
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000044432
Gene: ENSMUSG00000051278
AA Change: C1589R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.7e-23 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
906 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
1109 |
1153 |
1.5e-17 |
PFAM |
|
low complexity region
|
1316 |
1328 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
1501 |
1608 |
1.6e-21 |
PFAM |
|
Pfam:AAA_12
|
1616 |
1802 |
1.3e-51 |
PFAM |
|
coiled coil region
|
1833 |
1861 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000196141
AA Change: C1589R
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000143761
Gene: ENSMUSG00000051278
AA Change: C1589R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.7e-23 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
906 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
1109 |
1153 |
1.5e-17 |
PFAM |
|
low complexity region
|
1316 |
1328 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
1501 |
1608 |
1.6e-21 |
PFAM |
|
Pfam:AAA_12
|
1616 |
1802 |
1.3e-51 |
PFAM |
|
coiled coil region
|
1833 |
1861 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000196341
AA Change: V662A
PolyPhen 2
Score 0.971 (Sensitivity: 0.77; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000143570
Gene: ENSMUSG00000051278
AA Change: V662A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
22 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
225 |
269 |
6.7e-15 |
PFAM |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
491 |
659 |
7.1e-7 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199888
|
| SMART Domains |
Protein: ENSMUSP00000142693
Gene: ENSMUSG00000051278
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
82 |
3.5e-22 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200490
|
| SMART Domains |
Protein: ENSMUSP00000143585
Gene: ENSMUSG00000051278
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.4e-20 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.5991 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.7%
|
| Validation Efficiency |
97% (76/78) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9530002B09Rik |
T |
A |
4: 122,689,322 (GRCm38) |
|
probably benign |
Het |
| Abca2 |
A |
T |
2: 25,437,505 (GRCm38) |
I669F |
possibly damaging |
Het |
| Acin1 |
T |
A |
14: 54,665,254 (GRCm38) |
Q360H |
probably damaging |
Het |
| Aldh3b1 |
T |
A |
19: 3,921,755 (GRCm38) |
D72V |
probably benign |
Het |
| Alox12e |
G |
A |
11: 70,316,002 (GRCm38) |
R620W |
probably damaging |
Het |
| Alpl |
T |
C |
4: 137,749,545 (GRCm38) |
|
probably benign |
Het |
| Amy2a1 |
T |
C |
3: 113,530,568 (GRCm38) |
I108V |
probably benign |
Het |
| Ascc2 |
A |
T |
11: 4,681,496 (GRCm38) |
M646L |
probably benign |
Het |
| Bod1l |
G |
A |
5: 41,817,086 (GRCm38) |
T2295M |
probably benign |
Het |
| Ccdc9 |
A |
T |
7: 16,278,550 (GRCm38) |
|
probably null |
Het |
| Clptm1l |
C |
T |
13: 73,607,723 (GRCm38) |
Q153* |
probably null |
Het |
| Csmd1 |
A |
G |
8: 15,900,782 (GRCm38) |
S3476P |
probably benign |
Het |
| Ddias |
A |
T |
7: 92,859,699 (GRCm38) |
M336K |
possibly damaging |
Het |
| Ehd1 |
T |
C |
19: 6,298,078 (GRCm38) |
L362P |
probably benign |
Het |
| Epha1 |
G |
T |
6: 42,366,053 (GRCm38) |
H187Q |
probably benign |
Het |
| Espl1 |
T |
C |
15: 102,299,090 (GRCm38) |
S330P |
probably damaging |
Het |
| Fbln7 |
G |
T |
2: 128,877,466 (GRCm38) |
R61L |
probably damaging |
Het |
| Fbxo41 |
C |
T |
6: 85,478,471 (GRCm38) |
W577* |
probably null |
Het |
| Fgb |
C |
A |
3: 83,049,689 (GRCm38) |
D25Y |
probably benign |
Het |
| Gc |
T |
A |
5: 89,446,517 (GRCm38) |
K37N |
probably damaging |
Het |
| Gfpt1 |
T |
C |
6: 87,057,754 (GRCm38) |
I178T |
probably benign |
Het |
| Gm12695 |
T |
C |
4: 96,769,726 (GRCm38) |
T69A |
probably benign |
Het |
| Gm3944 |
C |
A |
12: 18,853,894 (GRCm38) |
S8* |
probably null |
Het |
| Gm9912 |
T |
C |
3: 149,185,159 (GRCm38) |
T113A |
unknown |
Het |
| Gpr156 |
A |
G |
16: 37,978,751 (GRCm38) |
D109G |
probably benign |
Het |
| Hoxd1 |
A |
T |
2: 74,763,366 (GRCm38) |
T89S |
probably benign |
Het |
| Htt |
C |
T |
5: 34,825,982 (GRCm38) |
T975I |
probably benign |
Het |
| Itpr3 |
G |
A |
17: 27,098,076 (GRCm38) |
M768I |
probably benign |
Het |
| Krt4 |
C |
A |
15: 101,924,664 (GRCm38) |
A3S |
possibly damaging |
Het |
| Mrto4 |
T |
C |
4: 139,349,023 (GRCm38) |
K86E |
probably benign |
Het |
| Mup4 |
T |
A |
4: 59,960,622 (GRCm38) |
|
probably benign |
Het |
| Myh1 |
G |
A |
11: 67,214,620 (GRCm38) |
D1079N |
possibly damaging |
Het |
| Myo1a |
A |
G |
10: 127,705,478 (GRCm38) |
N43D |
probably benign |
Het |
| Napa |
A |
T |
7: 16,115,278 (GRCm38) |
|
probably benign |
Het |
| Ndufa12 |
A |
G |
10: 94,220,707 (GRCm38) |
D99G |
probably damaging |
Het |
| Neb |
A |
G |
2: 52,284,263 (GRCm38) |
I1528T |
probably benign |
Het |
| Nek1 |
T |
C |
8: 61,007,162 (GRCm38) |
S41P |
probably damaging |
Het |
| Nolc1 |
C |
T |
19: 46,083,607 (GRCm38) |
T612M |
probably damaging |
Het |
| Nsun5 |
T |
G |
5: 135,375,072 (GRCm38) |
Y301D |
probably damaging |
Het |
| Oas1g |
T |
C |
5: 120,885,883 (GRCm38) |
E121G |
probably damaging |
Het |
| Olfr1085 |
G |
T |
2: 86,658,437 (GRCm38) |
T7K |
probably damaging |
Het |
| Olfr1170 |
A |
G |
2: 88,224,474 (GRCm38) |
V186A |
possibly damaging |
Het |
| Olfr324 |
A |
G |
11: 58,597,570 (GRCm38) |
N58S |
probably damaging |
Het |
| Olfr397 |
A |
G |
11: 73,964,914 (GRCm38) |
Y102C |
probably damaging |
Het |
| Olfr522 |
T |
A |
7: 140,162,909 (GRCm38) |
I14F |
possibly damaging |
Het |
| Olfr910 |
T |
A |
9: 38,539,280 (GRCm38) |
N128K |
probably benign |
Het |
| Osmr |
T |
C |
15: 6,815,415 (GRCm38) |
N957D |
probably benign |
Het |
| Parn |
G |
A |
16: 13,603,069 (GRCm38) |
S473L |
probably damaging |
Het |
| Phc2 |
T |
C |
4: 128,747,136 (GRCm38) |
F672S |
probably damaging |
Het |
| Pik3c2b |
T |
C |
1: 133,099,611 (GRCm38) |
S1283P |
probably damaging |
Het |
| Pole2 |
G |
A |
12: 69,228,152 (GRCm38) |
R5W |
probably benign |
Het |
| Prl7a2 |
T |
A |
13: 27,660,887 (GRCm38) |
Y172F |
probably damaging |
Het |
| Ptprz1 |
A |
G |
6: 23,050,389 (GRCm38) |
|
probably benign |
Het |
| Rapgef3 |
C |
A |
15: 97,766,961 (GRCm38) |
G7V |
probably damaging |
Het |
| Ripor1 |
T |
A |
8: 105,617,708 (GRCm38) |
S491R |
probably benign |
Het |
| Rnf141 |
A |
G |
7: 110,821,365 (GRCm38) |
|
probably benign |
Het |
| Ryr3 |
C |
T |
2: 112,946,957 (GRCm38) |
R285Q |
probably damaging |
Het |
| Sall4 |
T |
C |
2: 168,756,545 (GRCm38) |
N125S |
probably benign |
Het |
| Schip1 |
A |
G |
3: 68,617,786 (GRCm38) |
K360R |
probably damaging |
Het |
| Senp6 |
T |
A |
9: 80,089,869 (GRCm38) |
V55E |
probably benign |
Het |
| Skint1 |
T |
A |
4: 112,025,533 (GRCm38) |
V258D |
probably benign |
Het |
| Slc25a16 |
T |
A |
10: 62,932,751 (GRCm38) |
H130Q |
probably benign |
Het |
| Styx |
T |
C |
14: 45,373,563 (GRCm38) |
V217A |
probably benign |
Het |
| Syne2 |
G |
A |
12: 75,888,342 (GRCm38) |
|
probably null |
Het |
| Tagap1 |
A |
G |
17: 6,956,860 (GRCm38) |
S146P |
probably benign |
Het |
| Tatdn2 |
A |
G |
6: 113,704,142 (GRCm38) |
K379E |
probably benign |
Het |
| Thrap3 |
T |
C |
4: 126,175,396 (GRCm38) |
Y654C |
possibly damaging |
Het |
| Tle2 |
T |
C |
10: 81,580,551 (GRCm38) |
L135P |
probably damaging |
Het |
| Tmc1 |
A |
G |
19: 20,824,309 (GRCm38) |
F451S |
possibly damaging |
Het |
| Trpm7 |
G |
A |
2: 126,797,727 (GRCm38) |
P1650S |
probably damaging |
Het |
| Ttll4 |
G |
A |
1: 74,680,382 (GRCm38) |
R16H |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,714,373 (GRCm38) |
N32795S |
probably damaging |
Het |
| Tubgcp6 |
T |
C |
15: 89,104,489 (GRCm38) |
E803G |
probably benign |
Het |
| Ubr2 |
A |
G |
17: 46,963,145 (GRCm38) |
|
probably null |
Het |
| Ugt2b35 |
A |
G |
5: 87,001,553 (GRCm38) |
D221G |
probably damaging |
Het |
| Unc45b |
G |
A |
11: 82,911,689 (GRCm38) |
A4T |
probably benign |
Het |
| Vmn1r70 |
A |
T |
7: 10,634,337 (GRCm38) |
I251F |
possibly damaging |
Het |
| Vmn2r120 |
T |
A |
17: 57,524,553 (GRCm38) |
H412L |
possibly damaging |
Het |
| Zfp59 |
A |
G |
7: 27,853,510 (GRCm38) |
N129S |
probably benign |
Het |
|
| Other mutations in Zgrf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01088:Zgrf1
|
APN |
3 |
127,588,141 (GRCm38) |
splice site |
probably benign |
|
|
IGL01153:Zgrf1
|
APN |
3 |
127,602,406 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01330:Zgrf1
|
APN |
3 |
127,584,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01501:Zgrf1
|
APN |
3 |
127,602,562 (GRCm38) |
splice site |
probably null |
|
|
IGL01827:Zgrf1
|
APN |
3 |
127,616,281 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL02600:Zgrf1
|
APN |
3 |
127,600,974 (GRCm38) |
splice site |
probably benign |
|
|
IGL03122:Zgrf1
|
APN |
3 |
127,588,133 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL03365:Zgrf1
|
APN |
3 |
127,598,774 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R0015_Zgrf1_014
|
UTSW |
3 |
127,555,397 (GRCm38) |
splice site |
probably benign |
|
|
R1298_Zgrf1_204
|
UTSW |
3 |
127,583,889 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7175_zgrf1_533
|
UTSW |
3 |
127,563,590 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0015:Zgrf1
|
UTSW |
3 |
127,555,397 (GRCm38) |
splice site |
probably benign |
|
|
R0243:Zgrf1
|
UTSW |
3 |
127,615,446 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0468:Zgrf1
|
UTSW |
3 |
127,562,041 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R0497:Zgrf1
|
UTSW |
3 |
127,584,650 (GRCm38) |
splice site |
probably benign |
|
|
R0505:Zgrf1
|
UTSW |
3 |
127,573,238 (GRCm38) |
missense |
probably benign |
0.30 |
|
R0511:Zgrf1
|
UTSW |
3 |
127,584,660 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0539:Zgrf1
|
UTSW |
3 |
127,615,192 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0617:Zgrf1
|
UTSW |
3 |
127,588,038 (GRCm38) |
missense |
probably benign |
0.39 |
|
R1298:Zgrf1
|
UTSW |
3 |
127,583,889 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1353:Zgrf1
|
UTSW |
3 |
127,611,803 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1593:Zgrf1
|
UTSW |
3 |
127,561,026 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R1846:Zgrf1
|
UTSW |
3 |
127,615,463 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1912:Zgrf1
|
UTSW |
3 |
127,563,137 (GRCm38) |
missense |
probably benign |
|
|
R2062:Zgrf1
|
UTSW |
3 |
127,613,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2064:Zgrf1
|
UTSW |
3 |
127,613,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2065:Zgrf1
|
UTSW |
3 |
127,613,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2066:Zgrf1
|
UTSW |
3 |
127,613,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2256:Zgrf1
|
UTSW |
3 |
127,561,997 (GRCm38) |
missense |
probably benign |
0.18 |
|
R2321:Zgrf1
|
UTSW |
3 |
127,562,407 (GRCm38) |
nonsense |
probably null |
|
|
R2381:Zgrf1
|
UTSW |
3 |
127,556,214 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2913:Zgrf1
|
UTSW |
3 |
127,598,707 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R3147:Zgrf1
|
UTSW |
3 |
127,584,148 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R3236:Zgrf1
|
UTSW |
3 |
127,613,375 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3237:Zgrf1
|
UTSW |
3 |
127,613,375 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4433:Zgrf1
|
UTSW |
3 |
127,562,078 (GRCm38) |
missense |
probably benign |
|
|
R4441:Zgrf1
|
UTSW |
3 |
127,586,137 (GRCm38) |
missense |
possibly damaging |
0.45 |
|
R4457:Zgrf1
|
UTSW |
3 |
127,595,929 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4498:Zgrf1
|
UTSW |
3 |
127,586,100 (GRCm38) |
nonsense |
probably null |
|
|
R4598:Zgrf1
|
UTSW |
3 |
127,601,030 (GRCm38) |
missense |
probably benign |
0.14 |
|
R4701:Zgrf1
|
UTSW |
3 |
127,598,704 (GRCm38) |
missense |
probably benign |
0.03 |
|
R4898:Zgrf1
|
UTSW |
3 |
127,602,436 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4944:Zgrf1
|
UTSW |
3 |
127,561,868 (GRCm38) |
nonsense |
probably null |
|
|
R5256:Zgrf1
|
UTSW |
3 |
127,602,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5294:Zgrf1
|
UTSW |
3 |
127,600,980 (GRCm38) |
missense |
probably benign |
0.14 |
|
R5358:Zgrf1
|
UTSW |
3 |
127,567,703 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5359:Zgrf1
|
UTSW |
3 |
127,601,165 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5447:Zgrf1
|
UTSW |
3 |
127,563,119 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R5569:Zgrf1
|
UTSW |
3 |
127,561,025 (GRCm38) |
missense |
probably benign |
0.33 |
|
R5887:Zgrf1
|
UTSW |
3 |
127,584,765 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5914:Zgrf1
|
UTSW |
3 |
127,561,023 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5925:Zgrf1
|
UTSW |
3 |
127,573,204 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R5936:Zgrf1
|
UTSW |
3 |
127,562,253 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R6087:Zgrf1
|
UTSW |
3 |
127,615,486 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6089:Zgrf1
|
UTSW |
3 |
127,595,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6181:Zgrf1
|
UTSW |
3 |
127,587,941 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6277:Zgrf1
|
UTSW |
3 |
127,598,812 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R6441:Zgrf1
|
UTSW |
3 |
127,588,034 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R6659:Zgrf1
|
UTSW |
3 |
127,616,506 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6857:Zgrf1
|
UTSW |
3 |
127,581,447 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6932:Zgrf1
|
UTSW |
3 |
127,559,632 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7008:Zgrf1
|
UTSW |
3 |
127,561,772 (GRCm38) |
missense |
probably benign |
0.18 |
|
R7175:Zgrf1
|
UTSW |
3 |
127,563,590 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7264:Zgrf1
|
UTSW |
3 |
127,563,569 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7272:Zgrf1
|
UTSW |
3 |
127,598,760 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7298:Zgrf1
|
UTSW |
3 |
127,583,650 (GRCm38) |
nonsense |
probably null |
|
|
R7412:Zgrf1
|
UTSW |
3 |
127,563,071 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7836:Zgrf1
|
UTSW |
3 |
127,563,431 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7945:Zgrf1
|
UTSW |
3 |
127,562,760 (GRCm38) |
missense |
probably benign |
0.37 |
|
R7996:Zgrf1
|
UTSW |
3 |
127,595,924 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R8165:Zgrf1
|
UTSW |
3 |
127,563,383 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R8198:Zgrf1
|
UTSW |
3 |
127,596,024 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8296:Zgrf1
|
UTSW |
3 |
127,583,995 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8298:Zgrf1
|
UTSW |
3 |
127,615,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8341:Zgrf1
|
UTSW |
3 |
127,560,915 (GRCm38) |
nonsense |
probably null |
|
|
R8445:Zgrf1
|
UTSW |
3 |
127,586,205 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9088:Zgrf1
|
UTSW |
3 |
127,583,677 (GRCm38) |
missense |
probably benign |
0.21 |
|
R9236:Zgrf1
|
UTSW |
3 |
127,584,663 (GRCm38) |
missense |
probably benign |
0.09 |
|
R9250:Zgrf1
|
UTSW |
3 |
127,586,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9253:Zgrf1
|
UTSW |
3 |
127,598,779 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9464:Zgrf1
|
UTSW |
3 |
127,584,092 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9647:Zgrf1
|
UTSW |
3 |
127,561,602 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9680:Zgrf1
|
UTSW |
3 |
127,615,567 (GRCm38) |
missense |
probably benign |
0.38 |
|
RF015:Zgrf1
|
UTSW |
3 |
127,563,233 (GRCm38) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGGTAACTTTTCAAAGCCTTCAG -3'
(R):5'- TGATGTACACAGAGAAACAGCTC -3'
Sequencing Primer
(F):5'- GCCTTCAGCTTGCTAGTTAGC -3'
(R):5'- GAGAAACAGCTCCATTTTTAAAGGC -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation