Mutagenetix > Incidental Mutation

Incidental Mutation 'R0148:Flnb'

22674

Institutional Source

Beutler Lab

Gene Symbol

Flnb

Ensembl Gene

ENSMUSG00000025278

Gene Name

filamin, beta

Synonyms

MMRRC Submission

038432-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R0148 (G1)

Quality Score

225

Status

Validated (trace)

Chromosome

Chromosomal Location

7817957-7951588 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 7939077 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 2307 (S2307P)

Ref Sequence

ENSEMBL: ENSMUSP00000052020 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000052678]

AlphaFold

Q80X90

Predicted Effect

probably benign
Transcript: ENSMUST00000052678
AA Change: S2307P

PolyPhen 2 Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)

SMART Domains

Protein: ENSMUSP00000052020
Gene: ENSMUSG00000025278
AA Change: S2307P

Domain	Start	End	E-Value	Type
CH	18	120	2.38e-26	SMART
CH	141	237	1.83e-18	SMART
IG_FLMN	253	350	1.17e-33	SMART
IG_FLMN	353	449	2.08e-34	SMART
IG_FLMN	451	546	3.42e-35	SMART
IG_FLMN	548	639	6.06e-27	SMART
IG_FLMN	644	739	1.94e-34	SMART
IG_FLMN	741	842	4.25e-31	SMART
IG_FLMN	844	941	5.16e-30	SMART
IG_FLMN	943	1037	5.12e-25	SMART
IG_FLMN	1039	1130	5.31e-41	SMART
IG_FLMN	1132	1225	1.4e-31	SMART
IG_FLMN	1227	1325	1.42e-32	SMART
IG_FLMN	1327	1418	5.19e-35	SMART
IG_FLMN	1420	1514	2.48e-41	SMART
IG_FLMN	1516	1611	3.15e-34	SMART
IG_FLMN	1613	1707	4.99e-37	SMART
IG_FLMN	1730	1819	4.44e-11	SMART
IG_FLMN	1820	1911	5.82e-38	SMART
IG_FLMN	1914	1997	5.68e-9	SMART
IG_FLMN	2001	2092	4.45e-34	SMART
IG_FLMN	2101	2188	1.24e-9	SMART
IG_FLMN	2192	2283	4.48e-39	SMART
IG_FLMN	2286	2378	2.94e-25	SMART
IG_FLMN	2383	2474	5.66e-27	SMART
IG_FLMN	2511	2602	1.63e-27	SMART

Meta Mutation Damage Score

0.5051

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 96.0%
20x: 91.8%

Validation Efficiency

86% (30/35)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
PHENOTYPE: Mutations in this gene cause skeletal defects including runting, premature mineralization, and bone fusion. Nullizygous mice show a delay and reduction in long bone growth. Truncation mutations cause early fusion of spinal vertebrae due to enhanced chondrocyte hypertrophy and early differentiation. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 76 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2m	T	C	6: 121,662,446 (GRCm38)		probably null	Het
Agtr1a	T	C	13: 30,381,944 (GRCm38)	S331P	probably benign	Het
Ank1	T	A	8: 23,123,977 (GRCm38)	N1545K	probably damaging	Het
Bahcc1	A	T	11: 120,268,404 (GRCm38)	Q152H	probably damaging	Het
Bend3	T	A	10: 43,511,950 (GRCm38)	Y780N	probably damaging	Het
Bod1l	G	T	5: 41,818,697 (GRCm38)	A1758E	possibly damaging	Het
Ctcfl	T	C	2: 173,118,547 (GRCm38)	D81G	possibly damaging	Het
Ddx39a	C	T	8: 83,722,476 (GRCm38)	R298C	possibly damaging	Het
Dock8	T	C	19: 25,119,459 (GRCm38)	L577P	probably benign	Het
Drc1	A	T	5: 30,281,489 (GRCm38)	N13I	possibly damaging	Het
Efl1	T	C	7: 82,671,670 (GRCm38)	S104P	probably damaging	Het
Eml4	T	A	17: 83,421,652 (GRCm38)	N85K	probably damaging	Het
Epb41l4a	T	C	18: 33,798,800 (GRCm38)	T581A	probably damaging	Het
Epha3	T	C	16: 63,612,944 (GRCm38)	D446G	possibly damaging	Het
Fam209	G	T	2: 172,473,980 (GRCm38)	G92C	probably damaging	Het
Fbln1	G	A	15: 85,230,826 (GRCm38)	R193H	probably damaging	Het
Fbxw21	A	G	9: 109,148,017 (GRCm38)		probably null	Het
Fgf17	C	T	14: 70,638,873 (GRCm38)	R49Q	probably damaging	Het
Galr1	A	G	18: 82,405,570 (GRCm38)	L194P	probably benign	Het
Gar1	T	C	3: 129,829,473 (GRCm38)	H89R	probably damaging	Het
Gbp4	T	A	5: 105,119,496 (GRCm38)	Y519F	probably benign	Het
Git1	A	G	11: 77,505,728 (GRCm38)	T601A	probably benign	Het
Gm10722	T	"C,A"	9: 3,001,405 (GRCm38)		probably null	Het
Gm5142	C	T	14: 59,178,670 (GRCm38)	R13H	possibly damaging	Het
Gria2	A	C	3: 80,707,731 (GRCm38)	W481G	probably damaging	Het
Homer2	T	C	7: 81,624,278 (GRCm38)	T57A	probably benign	Het
Hpse2	A	C	19: 42,931,660 (GRCm38)		probably null	Het
Hspb7	T	C	4: 141,423,991 (GRCm38)	I148T	probably damaging	Het
Htr1d	C	A	4: 136,443,477 (GRCm38)	T339K	probably damaging	Het
Il4ra	T	A	7: 125,575,537 (GRCm38)	C306S	probably damaging	Het
Kansl3	A	T	1: 36,353,816 (GRCm38)	C225S	probably damaging	Het
Lama3	G	A	18: 12,448,272 (GRCm38)	C596Y	probably damaging	Het
Lama5	T	C	2: 180,190,406 (GRCm38)	H1714R	probably benign	Het
Marchf6	C	T	15: 31,490,612 (GRCm38)	V293M	probably damaging	Het
Med12l	A	G	3: 59,037,654 (GRCm38)	D100G	probably damaging	Het
Mettl14	G	A	3: 123,371,394 (GRCm38)	T316I	probably damaging	Het
Mmp15	A	T	8: 95,372,317 (GRCm38)	N591Y	probably benign	Het
Mrpl53	T	C	6: 83,109,537 (GRCm38)	L74P	probably damaging	Het
Mvp	C	T	7: 126,989,865 (GRCm38)	V577M	probably damaging	Het
Neb	T	C	2: 52,249,376 (GRCm38)	K140E	probably damaging	Het
Nfya	A	G	17: 48,398,998 (GRCm38)	V48A	possibly damaging	Het
Ngf	G	T	3: 102,509,803 (GRCm38)		probably benign	Het
Nipsnap3b	C	T	4: 53,017,088 (GRCm38)	A104V	possibly damaging	Het
Nlrp14	A	G	7: 107,182,721 (GRCm38)	Y375C	probably benign	Het
Nod1	A	G	6: 54,938,217 (GRCm38)	Y764H	probably damaging	Het
Or13d1	A	T	4: 52,971,232 (GRCm38)	I204F	probably benign	Het
Or2w25	G	A	11: 59,613,494 (GRCm38)	V177M	probably damaging	Het
Or7e177	T	G	9: 20,301,091 (GRCm38)	M297R	probably damaging	Het
Pcdhb19	A	T	18: 37,497,182 (GRCm38)	Q10L	probably benign	Het
Pdcl	T	C	2: 37,352,130 (GRCm38)	I203V	probably benign	Het
Peg10	C	A	6: 4,755,711 (GRCm38)	R96S	possibly damaging	Het
Pknox1	T	A	17: 31,604,790 (GRCm38)	N379K	probably benign	Het
Prodh	T	G	16: 18,077,813 (GRCm38)	Q360P	probably damaging	Het
Raf1	C	T	6: 115,632,973 (GRCm38)	G202S	probably benign	Het
Rgs11	T	A	17: 26,207,459 (GRCm38)		probably null	Het
Rilp	A	T	11: 75,510,233 (GRCm38)	H29L	probably damaging	Het
Rtel1	T	C	2: 181,321,046 (GRCm38)	C31R	probably damaging	Het
Rubcnl	T	A	14: 75,042,458 (GRCm38)	I427K	probably damaging	Het
Ryr1	C	A	7: 29,052,035 (GRCm38)	R3706L	probably damaging	Het
Ryr2	T	C	13: 11,714,548 (GRCm38)	D2396G	probably damaging	Het
Slc45a2	T	C	15: 11,025,868 (GRCm38)	S435P	probably damaging	Het
Spata17	A	G	1: 187,112,601 (GRCm38)	V111A	probably damaging	Het
Svep1	C	T	4: 58,116,608 (GRCm38)	D881N	possibly damaging	Het
Sypl2	T	A	3: 108,219,095 (GRCm38)	N67I	possibly damaging	Het
Tenm3	T	C	8: 48,236,720 (GRCm38)	Y1944C	probably damaging	Het
Tep1	A	T	14: 50,824,789 (GRCm38)	D2535E	possibly damaging	Het
Tkt	T	A	14: 30,572,220 (GRCm38)	I529N	probably damaging	Het
Trp53i11	T	G	2: 93,197,735 (GRCm38)	V39G	probably damaging	Het
Trpm2	C	T	10: 77,925,825 (GRCm38)	G997D	probably damaging	Het
Usp3	A	G	9: 66,540,167 (GRCm38)	V219A	possibly damaging	Het
Usp4	T	A	9: 108,391,671 (GRCm38)		probably null	Het
Wdfy3	A	G	5: 101,917,411 (GRCm38)	V1297A	probably benign	Het
Wdr46	T	A	17: 33,941,023 (GRCm38)	F70I	probably benign	Het
Xkr6	T	C	14: 63,819,549 (GRCm38)	V303A	unknown	Het
Zdbf2	C	T	1: 63,304,006 (GRCm38)	Q515*	probably null	Het
Zfhx2	A	G	14: 55,072,897 (GRCm38)	Y731H	possibly damaging	Het

Other mutations in Flnb

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01017:Flnb	APN	14	7,917,390 (GRCm38)	splice site	probably benign
IGL01063:Flnb	APN	14	7,926,518 (GRCm38)	splice site	probably benign
IGL01135:Flnb	APN	14	7,909,736 (GRCm38)	missense	probably benign
IGL01139:Flnb	APN	14	7,945,989 (GRCm38)	missense	probably damaging	1.00
IGL01364:Flnb	APN	14	7,934,562 (GRCm38)	critical splice acceptor site	probably null
IGL01417:Flnb	APN	14	7,905,513 (GRCm38)	missense	probably damaging	0.99
IGL01505:Flnb	APN	14	7,902,003 (GRCm38)	critical splice donor site	probably null
IGL01560:Flnb	APN	14	7,893,829 (GRCm38)	missense	probably benign	0.07
IGL01621:Flnb	APN	14	7,950,470 (GRCm38)	missense	probably damaging	1.00
IGL01656:Flnb	APN	14	7,902,010 (GRCm38)	splice site	probably benign
IGL01889:Flnb	APN	14	7,935,967 (GRCm38)	missense	possibly damaging	0.85
IGL01987:Flnb	APN	14	7,922,748 (GRCm38)	critical splice donor site	probably null
IGL02322:Flnb	APN	14	7,894,676 (GRCm38)	missense	probably damaging	1.00
IGL02496:Flnb	APN	14	7,930,919 (GRCm38)	splice site	probably benign
IGL02752:Flnb	APN	14	7,917,338 (GRCm38)	missense	probably benign
IGL03001:Flnb	APN	14	7,934,680 (GRCm38)	missense	probably damaging	0.99
IGL03076:Flnb	APN	14	7,901,988 (GRCm38)	missense	probably benign	0.01
IGL03085:Flnb	APN	14	7,882,211 (GRCm38)	missense	probably benign
IGL03170:Flnb	APN	14	7,818,261 (GRCm38)	missense	possibly damaging	0.90
IGL03373:Flnb	APN	14	7,890,867 (GRCm38)	critical splice donor site	probably null
Boomerang	UTSW	14	7,901,945 (GRCm38)	missense	probably damaging	1.00
Queensland	UTSW	14	7,927,352 (GRCm38)	missense	probably damaging	1.00
R3437_Flnb_252	UTSW	14	7,942,057 (GRCm38)	missense	probably damaging	0.97
R8441_Flnb_221	UTSW	14	7,896,488 (GRCm38)	missense	probably benign	0.15
Rhodelinda	UTSW	14	7,887,682 (GRCm38)	splice site	probably benign
saul	UTSW	14	7,889,183 (GRCm38)	missense	probably damaging	0.99
Xerxes	UTSW	14	7,867,551 (GRCm38)	missense	probably damaging	1.00
R0068:Flnb	UTSW	14	7,915,290 (GRCm38)	missense	possibly damaging	0.49
R0068:Flnb	UTSW	14	7,915,290 (GRCm38)	missense	possibly damaging	0.49
R0084:Flnb	UTSW	14	7,935,979 (GRCm38)	missense	probably benign
R0128:Flnb	UTSW	14	7,901,951 (GRCm38)	missense	probably damaging	0.99
R0130:Flnb	UTSW	14	7,901,951 (GRCm38)	missense	probably damaging	0.99
R0166:Flnb	UTSW	14	7,896,115 (GRCm38)	missense	probably damaging	1.00
R0376:Flnb	UTSW	14	7,946,014 (GRCm38)	critical splice donor site	probably null
R0547:Flnb	UTSW	14	7,912,943 (GRCm38)	splice site	probably null
R0612:Flnb	UTSW	14	7,887,682 (GRCm38)	splice site	probably benign
R0656:Flnb	UTSW	14	7,927,352 (GRCm38)	missense	probably damaging	1.00
R0691:Flnb	UTSW	14	7,890,810 (GRCm38)	missense	probably benign	0.16
R1241:Flnb	UTSW	14	7,896,503 (GRCm38)	missense	probably benign	0.06
R1572:Flnb	UTSW	14	7,883,908 (GRCm38)	missense	probably damaging	0.97
R1682:Flnb	UTSW	14	7,913,121 (GRCm38)	missense	probably benign	0.04
R1807:Flnb	UTSW	14	7,934,645 (GRCm38)	missense	probably benign	0.26
R1848:Flnb	UTSW	14	7,892,113 (GRCm38)	missense	probably damaging	1.00
R1959:Flnb	UTSW	14	7,884,735 (GRCm38)	nonsense	probably null
R2078:Flnb	UTSW	14	7,927,466 (GRCm38)	missense	probably damaging	1.00
R2132:Flnb	UTSW	14	7,873,376 (GRCm38)	missense	probably benign	0.04
R2209:Flnb	UTSW	14	7,905,507 (GRCm38)	nonsense	probably null
R2212:Flnb	UTSW	14	7,881,652 (GRCm38)	small deletion	probably benign
R2213:Flnb	UTSW	14	7,881,652 (GRCm38)	small deletion	probably benign
R2363:Flnb	UTSW	14	7,945,950 (GRCm38)	missense	possibly damaging	0.95
R2415:Flnb	UTSW	14	7,929,932 (GRCm38)	missense	probably benign	0.07
R2983:Flnb	UTSW	14	7,882,250 (GRCm38)	missense	probably damaging	1.00
R3001:Flnb	UTSW	14	7,907,162 (GRCm38)	missense	probably benign	0.22
R3002:Flnb	UTSW	14	7,907,162 (GRCm38)	missense	probably benign	0.22
R3436:Flnb	UTSW	14	7,942,057 (GRCm38)	missense	probably damaging	0.97
R3437:Flnb	UTSW	14	7,942,057 (GRCm38)	missense	probably damaging	0.97
R3778:Flnb	UTSW	14	7,915,353 (GRCm38)	missense	probably benign	0.06
R3783:Flnb	UTSW	14	7,889,236 (GRCm38)	missense	probably benign	0.04
R4162:Flnb	UTSW	14	7,915,374 (GRCm38)	missense	possibly damaging	0.81
R4163:Flnb	UTSW	14	7,915,374 (GRCm38)	missense	possibly damaging	0.81
R4164:Flnb	UTSW	14	7,915,374 (GRCm38)	missense	possibly damaging	0.81
R4356:Flnb	UTSW	14	7,922,700 (GRCm38)	missense	probably benign
R4369:Flnb	UTSW	14	7,942,216 (GRCm38)	missense	probably benign
R4783:Flnb	UTSW	14	7,905,701 (GRCm38)	missense	probably benign	0.12
R4785:Flnb	UTSW	14	7,905,701 (GRCm38)	missense	probably benign	0.12
R4790:Flnb	UTSW	14	7,905,661 (GRCm38)	missense	probably benign	0.34
R4828:Flnb	UTSW	14	7,919,238 (GRCm38)	missense	probably benign	0.13
R4882:Flnb	UTSW	14	7,929,936 (GRCm38)	missense	possibly damaging	0.56
R5002:Flnb	UTSW	14	7,945,882 (GRCm38)	missense	probably damaging	1.00
R5058:Flnb	UTSW	14	7,924,262 (GRCm38)	nonsense	probably null
R5184:Flnb	UTSW	14	7,901,945 (GRCm38)	missense	probably damaging	1.00
R5186:Flnb	UTSW	14	7,909,748 (GRCm38)	missense	probably damaging	1.00
R5395:Flnb	UTSW	14	7,883,881 (GRCm38)	missense	probably benign	0.02
R5421:Flnb	UTSW	14	7,926,494 (GRCm38)	missense	probably damaging	1.00
R5667:Flnb	UTSW	14	7,890,843 (GRCm38)	missense	probably benign	0.00
R5671:Flnb	UTSW	14	7,890,843 (GRCm38)	missense	probably benign	0.00
R5714:Flnb	UTSW	14	7,929,073 (GRCm38)	missense	probably damaging	1.00
R5860:Flnb	UTSW	14	7,931,135 (GRCm38)	missense	probably damaging	1.00
R5892:Flnb	UTSW	14	7,907,183 (GRCm38)	missense	probably damaging	1.00
R5924:Flnb	UTSW	14	7,890,765 (GRCm38)	missense	probably benign	0.00
R6131:Flnb	UTSW	14	7,894,635 (GRCm38)	missense	possibly damaging	0.79
R6244:Flnb	UTSW	14	7,892,092 (GRCm38)	missense	probably damaging	1.00
R6489:Flnb	UTSW	14	7,867,551 (GRCm38)	missense	probably damaging	1.00
R6582:Flnb	UTSW	14	7,892,275 (GRCm38)	critical splice donor site	probably null
R6586:Flnb	UTSW	14	7,929,138 (GRCm38)	missense	possibly damaging	0.93
R6611:Flnb	UTSW	14	7,915,318 (GRCm38)	missense	probably damaging	1.00
R6626:Flnb	UTSW	14	7,929,012 (GRCm38)	missense	probably damaging	1.00
R6700:Flnb	UTSW	14	7,892,189 (GRCm38)	missense	probably damaging	0.99
R6738:Flnb	UTSW	14	7,904,536 (GRCm38)	missense	probably benign	0.01
R6864:Flnb	UTSW	14	7,905,640 (GRCm38)	missense	possibly damaging	0.84
R6916:Flnb	UTSW	14	7,907,171 (GRCm38)	missense	probably damaging	0.99
R7117:Flnb	UTSW	14	7,894,214 (GRCm38)	missense	probably benign	0.02
R7164:Flnb	UTSW	14	7,915,944 (GRCm38)	splice site	probably null
R7328:Flnb	UTSW	14	7,894,660 (GRCm38)	nonsense	probably null
R7328:Flnb	UTSW	14	7,883,788 (GRCm38)	missense	possibly damaging	0.95
R7687:Flnb	UTSW	14	7,924,224 (GRCm38)	missense	probably damaging	1.00
R7716:Flnb	UTSW	14	7,917,274 (GRCm38)	missense	possibly damaging	0.64
R7763:Flnb	UTSW	14	7,926,478 (GRCm38)	missense	probably benign	0.00
R7821:Flnb	UTSW	14	7,939,113 (GRCm38)	missense	probably benign	0.00
R7921:Flnb	UTSW	14	7,933,800 (GRCm38)	missense	possibly damaging	0.57
R8008:Flnb	UTSW	14	7,892,155 (GRCm38)	missense	probably damaging	1.00
R8075:Flnb	UTSW	14	7,913,048 (GRCm38)	missense	probably benign	0.00
R8084:Flnb	UTSW	14	7,907,243 (GRCm38)	missense	probably benign	0.00
R8259:Flnb	UTSW	14	7,889,183 (GRCm38)	missense	probably damaging	0.99
R8441:Flnb	UTSW	14	7,896,488 (GRCm38)	missense	probably benign	0.15
R8493:Flnb	UTSW	14	7,869,822 (GRCm38)	missense	probably damaging	0.97
R8508:Flnb	UTSW	14	7,950,394 (GRCm38)	missense	probably damaging	0.98
R8531:Flnb	UTSW	14	7,929,939 (GRCm38)	missense	probably damaging	1.00
R8812:Flnb	UTSW	14	7,887,624 (GRCm38)	missense	probably benign	0.06
R8814:Flnb	UTSW	14	7,927,409 (GRCm38)	missense	probably damaging	1.00
R8825:Flnb	UTSW	14	7,887,566 (GRCm38)	missense	probably damaging	1.00
R8868:Flnb	UTSW	14	7,908,671 (GRCm38)	missense	probably benign	0.02
R8955:Flnb	UTSW	14	7,904,688 (GRCm38)	nonsense	probably null
R8955:Flnb	UTSW	14	7,892,874 (GRCm38)	missense	probably damaging	1.00
R8976:Flnb	UTSW	14	7,901,882 (GRCm38)	critical splice acceptor site	probably null
R9055:Flnb	UTSW	14	7,908,553 (GRCm38)	missense	probably benign	0.00
R9148:Flnb	UTSW	14	7,817,996 (GRCm38)	start gained	probably benign
R9179:Flnb	UTSW	14	7,887,541 (GRCm38)	nonsense	probably null
R9180:Flnb	UTSW	14	7,818,219 (GRCm38)	missense	probably damaging	1.00
R9189:Flnb	UTSW	14	7,892,976 (GRCm38)	missense	possibly damaging	0.90
R9286:Flnb	UTSW	14	7,873,414 (GRCm38)	missense	probably damaging	0.98
R9288:Flnb	UTSW	14	7,904,498 (GRCm38)	missense	probably benign	0.43
R9354:Flnb	UTSW	14	7,818,411 (GRCm38)	missense	probably benign	0.13
R9484:Flnb	UTSW	14	7,929,004 (GRCm38)	missense	probably benign	0.06
R9505:Flnb	UTSW	14	7,904,665 (GRCm38)	missense	probably benign
R9525:Flnb	UTSW	14	7,905,481 (GRCm38)	missense	probably damaging	1.00
R9621:Flnb	UTSW	14	7,926,421 (GRCm38)	missense	probably damaging	0.99
R9630:Flnb	UTSW	14	7,926,438 (GRCm38)	nonsense	probably null
R9739:Flnb	UTSW	14	7,935,954 (GRCm38)	nonsense	probably null
R9760:Flnb	UTSW	14	7,929,846 (GRCm38)	missense	probably damaging	0.98
X0066:Flnb	UTSW	14	7,908,636 (GRCm38)	missense	probably damaging	1.00
Z1088:Flnb	UTSW	14	7,905,871 (GRCm38)	missense	probably benign	0.04
Z1176:Flnb	UTSW	14	7,942,066 (GRCm38)	missense	probably benign	0.25

Predicted Primers

PCR Primer
(F):5'- CTGCCCCGTCTTGTTATCAGGTATG -3'
(R):5'- GGGTATTGCTGTCACACAGAGAGTC -3'

Sequencing Primer
(F):5'- GTCTTGTTATCAGGTATGACAGATG -3'
(R):5'- CCCATTTTAGAAACGATGCCTGG -3'

Posted On

2013-04-16