Incidental Mutation 'R2069:Cdh7'
| ID |
226905 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cdh7
|
| Ensembl Gene |
ENSMUSG00000026312 |
| Gene Name |
cadherin 7, type 2 |
| Synonyms |
CDH7L1 |
| MMRRC Submission |
040074-MU
|
| Accession Numbers |
Ncbi RefSeq: NM_172853.2; MGI:2442792
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2069 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
109982431-110140157 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 110138159 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 721
(D721V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000129715
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027542]
[ENSMUST00000112701]
[ENSMUST00000131464]
[ENSMUST00000172005]
|
| AlphaFold |
Q8BM92 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000027542
AA Change: D721V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000027542
Gene: ENSMUSG00000026312
AA Change: D721V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
CA
|
70 |
151 |
5.77e-16 |
SMART |
|
CA
|
175 |
260 |
2.9e-30 |
SMART |
|
CA
|
284 |
376 |
1.96e-18 |
SMART |
|
CA
|
399 |
480 |
1.19e-26 |
SMART |
|
CA
|
503 |
590 |
2.26e-9 |
SMART |
|
transmembrane domain
|
606 |
628 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
633 |
778 |
6e-54 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112701
AA Change: D721V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108321
Gene: ENSMUSG00000026312
AA Change: D721V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
CA
|
70 |
151 |
5.77e-16 |
SMART |
|
CA
|
175 |
260 |
2.9e-30 |
SMART |
|
CA
|
284 |
376 |
1.96e-18 |
SMART |
|
CA
|
399 |
480 |
1.19e-26 |
SMART |
|
CA
|
503 |
590 |
2.26e-9 |
SMART |
|
transmembrane domain
|
606 |
628 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
631 |
779 |
4e-58 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131464
|
| SMART Domains |
Protein: ENSMUSP00000138046
Gene: ENSMUSG00000026312
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
PDB:1ZVN|B
|
49 |
70 |
1e-9 |
PDB |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000134301
|
| SMART Domains |
Protein: ENSMUSP00000123394
Gene: ENSMUSG00000026312
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
24 |
111 |
2.26e-9 |
SMART |
|
transmembrane domain
|
125 |
147 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000172005
AA Change: D721V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000129715
Gene: ENSMUSG00000026312
AA Change: D721V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
CA
|
70 |
151 |
5.77e-16 |
SMART |
|
CA
|
175 |
260 |
2.9e-30 |
SMART |
|
CA
|
284 |
376 |
1.96e-18 |
SMART |
|
CA
|
399 |
480 |
1.19e-26 |
SMART |
|
CA
|
503 |
590 |
2.26e-9 |
SMART |
|
transmembrane domain
|
606 |
628 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
631 |
779 |
4e-58 |
PFAM |
|
| Meta Mutation Damage Score |
0.9124 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
100% (104/104) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related cadherin gene on chromosome 1. [provided by RefSeq, Oct 2015]
|
| Allele List at MGI |
All alleles(1) : Targeted(1)
|
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930519G04Rik |
T |
C |
5: 114,874,280 (GRCm38) |
V86A |
probably benign |
Het |
| Abcc3 |
A |
T |
11: 94,364,417 (GRCm38) |
I601N |
probably damaging |
Het |
| Abl2 |
T |
A |
1: 156,620,827 (GRCm38) |
|
probably null |
Het |
| Adgrf4 |
C |
T |
17: 42,666,898 (GRCm38) |
R518Q |
possibly damaging |
Het |
| Ahi1 |
C |
T |
10: 20,959,996 (GRCm38) |
T76I |
probably damaging |
Het |
| Arhgap42 |
C |
T |
9: 9,035,600 (GRCm38) |
G247D |
probably damaging |
Het |
| Arid2 |
C |
T |
15: 96,362,590 (GRCm38) |
L407F |
probably damaging |
Het |
| Atp13a1 |
T |
C |
8: 69,799,773 (GRCm38) |
F606L |
probably benign |
Het |
| Avl9 |
T |
A |
6: 56,736,435 (GRCm38) |
|
probably benign |
Het |
| B3glct |
C |
T |
5: 149,709,380 (GRCm38) |
A65V |
probably damaging |
Het |
| Bcorl1 |
T |
C |
X: 48,401,917 (GRCm38) |
|
probably benign |
Het |
| Bdp1 |
T |
C |
13: 100,050,988 (GRCm38) |
T1624A |
probably benign |
Het |
| Bmp15 |
A |
G |
X: 6,316,021 (GRCm38) |
M263T |
probably benign |
Het |
| Brd8 |
T |
C |
18: 34,614,479 (GRCm38) |
K110E |
probably damaging |
Het |
| Cachd1 |
A |
G |
4: 100,990,844 (GRCm38) |
D1052G |
probably damaging |
Het |
| Capn9 |
G |
A |
8: 124,605,711 (GRCm38) |
G430R |
possibly damaging |
Het |
| Ccdc113 |
G |
A |
8: 95,557,296 (GRCm38) |
E333K |
probably benign |
Het |
| Ccnl2 |
A |
T |
4: 155,812,481 (GRCm38) |
|
probably null |
Het |
| Ccr9 |
T |
C |
9: 123,779,364 (GRCm38) |
F37S |
probably benign |
Het |
| Ceacam10 |
A |
T |
7: 24,778,372 (GRCm38) |
N104I |
probably damaging |
Het |
| Cenpk |
T |
A |
13: 104,236,176 (GRCm38) |
|
probably benign |
Het |
| Cfi |
A |
G |
3: 129,858,804 (GRCm38) |
|
probably null |
Het |
| Chd1 |
T |
C |
17: 15,742,294 (GRCm38) |
F771S |
probably damaging |
Het |
| Chil4 |
G |
A |
3: 106,219,455 (GRCm38) |
L4F |
probably benign |
Het |
| Cilp |
G |
A |
9: 65,278,090 (GRCm38) |
R489Q |
possibly damaging |
Het |
| Cntnap5b |
G |
A |
1: 100,358,725 (GRCm38) |
G402R |
probably benign |
Het |
| Coq8b |
A |
G |
7: 27,257,377 (GRCm38) |
E485G |
probably damaging |
Het |
| Cse1l |
A |
G |
2: 166,941,492 (GRCm38) |
S733G |
probably benign |
Het |
| Dnah5 |
G |
A |
15: 28,312,388 (GRCm38) |
|
probably null |
Het |
| Dnmt3l |
T |
C |
10: 78,052,732 (GRCm38) |
V156A |
probably damaging |
Het |
| Duox1 |
A |
T |
2: 122,333,062 (GRCm38) |
T792S |
probably benign |
Het |
| Duox2 |
T |
C |
2: 122,287,108 (GRCm38) |
D915G |
probably benign |
Het |
| Efcab5 |
A |
T |
11: 77,172,321 (GRCm38) |
M115K |
probably benign |
Het |
| Eif2s1 |
G |
A |
12: 78,877,185 (GRCm38) |
D139N |
probably benign |
Het |
| Erg |
A |
G |
16: 95,361,078 (GRCm38) |
F390L |
probably damaging |
Het |
| Fam193b |
A |
T |
13: 55,542,998 (GRCm38) |
S650R |
probably damaging |
Het |
| Fbp2 |
T |
A |
13: 62,854,061 (GRCm38) |
K113N |
possibly damaging |
Het |
| Fnbp4 |
T |
G |
2: 90,758,372 (GRCm38) |
S496A |
probably damaging |
Het |
| Gab3 |
C |
A |
X: 75,000,095 (GRCm38) |
R475L |
probably damaging |
Het |
| Gm7534 |
T |
G |
4: 134,201,941 (GRCm38) |
N351T |
possibly damaging |
Het |
| Gsap |
T |
C |
5: 21,226,839 (GRCm38) |
|
probably benign |
Het |
| Gucy1a2 |
C |
T |
9: 3,582,697 (GRCm38) |
L160F |
probably damaging |
Het |
| Hivep1 |
C |
T |
13: 42,183,786 (GRCm38) |
A2447V |
possibly damaging |
Het |
| Hrasls5 |
T |
C |
19: 7,612,638 (GRCm38) |
S10P |
possibly damaging |
Het |
| Insc |
G |
T |
7: 114,804,593 (GRCm38) |
|
probably null |
Het |
| Jph2 |
A |
G |
2: 163,339,685 (GRCm38) |
S520P |
possibly damaging |
Het |
| Kidins220 |
T |
A |
12: 24,987,006 (GRCm38) |
|
probably benign |
Het |
| Krtap29-1 |
A |
G |
11: 99,978,612 (GRCm38) |
S148P |
probably damaging |
Het |
| Ltbp2 |
A |
C |
12: 84,793,733 (GRCm38) |
C1000G |
probably damaging |
Het |
| Map2k3 |
T |
C |
11: 60,950,027 (GRCm38) |
F294S |
probably damaging |
Het |
| Map4k2 |
C |
A |
19: 6,342,738 (GRCm38) |
|
probably benign |
Het |
| Mboat2 |
T |
C |
12: 24,951,443 (GRCm38) |
V281A |
probably benign |
Het |
| Mdga2 |
G |
A |
12: 66,568,917 (GRCm38) |
R570* |
probably null |
Het |
| Mlxipl |
A |
G |
5: 135,107,005 (GRCm38) |
D28G |
probably damaging |
Het |
| Morc2b |
T |
C |
17: 33,136,760 (GRCm38) |
I679M |
probably benign |
Het |
| Myh4 |
T |
C |
11: 67,246,366 (GRCm38) |
|
probably benign |
Het |
| Nfib |
A |
C |
4: 82,498,615 (GRCm38) |
L61R |
probably damaging |
Het |
| Noc2l |
C |
A |
4: 156,241,450 (GRCm38) |
Y227* |
probably null |
Het |
| Nrde2 |
A |
G |
12: 100,142,232 (GRCm38) |
S367P |
probably damaging |
Het |
| Nup93 |
C |
A |
8: 94,243,739 (GRCm38) |
P89T |
probably damaging |
Het |
| Obsl1 |
G |
A |
1: 75,486,756 (GRCm38) |
T1764M |
probably benign |
Het |
| Olfr1240 |
C |
T |
2: 89,439,583 (GRCm38) |
R232H |
probably benign |
Het |
| Olfr1283 |
A |
G |
2: 111,369,095 (GRCm38) |
I154M |
probably benign |
Het |
| Olfr6 |
A |
T |
7: 106,956,287 (GRCm38) |
Y216* |
probably null |
Het |
| Olfr714 |
A |
T |
7: 107,074,619 (GRCm38) |
K264* |
probably null |
Het |
| Olfr749 |
T |
A |
14: 50,736,576 (GRCm38) |
E195D |
possibly damaging |
Het |
| Olfr824 |
A |
G |
10: 130,126,205 (GRCm38) |
I284T |
possibly damaging |
Het |
| Oxct1 |
G |
T |
15: 4,092,525 (GRCm38) |
A319S |
probably null |
Het |
| P2ry10 |
A |
G |
X: 107,103,253 (GRCm38) |
S265G |
probably benign |
Het |
| Peak1 |
A |
T |
9: 56,258,759 (GRCm38) |
N628K |
probably damaging |
Het |
| Pkdrej |
T |
A |
15: 85,821,231 (GRCm38) |
Q168L |
probably benign |
Het |
| Plec |
A |
G |
15: 76,188,926 (GRCm38) |
M604T |
probably benign |
Het |
| Pmfbp1 |
A |
T |
8: 109,532,103 (GRCm38) |
N680I |
possibly damaging |
Het |
| Pnmal2 |
T |
C |
7: 16,945,789 (GRCm38) |
W233R |
probably damaging |
Het |
| Pxn |
A |
G |
5: 115,545,667 (GRCm38) |
N186S |
probably benign |
Het |
| Rsad1 |
A |
C |
11: 94,549,125 (GRCm38) |
|
probably benign |
Het |
| Runx2 |
A |
G |
17: 44,735,342 (GRCm38) |
I112T |
probably benign |
Het |
| S1pr2 |
A |
T |
9: 20,967,494 (GRCm38) |
L346Q |
probably damaging |
Het |
| Skint6 |
A |
G |
4: 113,238,132 (GRCm38) |
I110T |
probably damaging |
Het |
| Slc36a4 |
T |
A |
9: 15,726,980 (GRCm38) |
F234Y |
probably damaging |
Het |
| Slitrk2 |
T |
A |
X: 66,654,629 (GRCm38) |
V242D |
probably damaging |
Het |
| Sp100 |
A |
G |
1: 85,681,142 (GRCm38) |
|
probably null |
Het |
| Spryd3 |
A |
C |
15: 102,118,181 (GRCm38) |
L352V |
probably benign |
Het |
| Ssc4d |
A |
C |
5: 135,970,317 (GRCm38) |
W11G |
possibly damaging |
Het |
| Stx17 |
T |
A |
4: 48,158,870 (GRCm38) |
D83E |
probably damaging |
Het |
| Tlk2 |
A |
T |
11: 105,240,440 (GRCm38) |
Q204L |
probably benign |
Het |
| Tnfrsf21 |
A |
T |
17: 43,037,938 (GRCm38) |
H147L |
possibly damaging |
Het |
| Tnrc18 |
A |
T |
5: 142,766,087 (GRCm38) |
D1154E |
unknown |
Het |
| Trap1 |
A |
G |
16: 4,068,336 (GRCm38) |
S86P |
probably benign |
Het |
| Trim32 |
T |
A |
4: 65,614,776 (GRCm38) |
C523* |
probably null |
Het |
| Ttc38 |
G |
T |
15: 85,838,788 (GRCm38) |
D146Y |
probably damaging |
Het |
| Ttc9 |
T |
A |
12: 81,631,796 (GRCm38) |
L131Q |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,813,339 (GRCm38) |
G11436R |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,726,848 (GRCm38) |
|
probably benign |
Het |
| Ubash3b |
G |
A |
9: 41,043,573 (GRCm38) |
P92S |
possibly damaging |
Het |
| Ube4a |
T |
C |
9: 44,948,099 (GRCm38) |
N367S |
probably damaging |
Het |
| Ubr4 |
T |
A |
4: 139,479,540 (GRCm38) |
H4899Q |
possibly damaging |
Het |
| Ufl1 |
C |
T |
4: 25,269,036 (GRCm38) |
G265D |
possibly damaging |
Het |
| Vmn2r27 |
T |
A |
6: 124,224,483 (GRCm38) |
I172F |
probably damaging |
Het |
| Vmn2r6 |
A |
T |
3: 64,556,098 (GRCm38) |
H438Q |
possibly damaging |
Het |
| Vmn2r61 |
A |
G |
7: 42,300,001 (GRCm38) |
D615G |
probably benign |
Het |
| Wdr24 |
T |
A |
17: 25,826,282 (GRCm38) |
D330E |
probably damaging |
Het |
| Zbbx |
A |
T |
3: 75,078,412 (GRCm38) |
N444K |
probably benign |
Het |
| Zc3h7b |
A |
T |
15: 81,792,328 (GRCm38) |
Q757L |
probably damaging |
Het |
|
| Other mutations in Cdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00742:Cdh7
|
APN |
1 |
110,065,626 (GRCm38) |
missense |
probably benign |
0.22 |
|
IGL00861:Cdh7
|
APN |
1 |
110,060,988 (GRCm38) |
splice site |
probably benign |
|
|
IGL01016:Cdh7
|
APN |
1 |
110,108,956 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01538:Cdh7
|
APN |
1 |
110,061,140 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01763:Cdh7
|
APN |
1 |
110,065,790 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01765:Cdh7
|
APN |
1 |
110,061,106 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01937:Cdh7
|
APN |
1 |
110,138,096 (GRCm38) |
missense |
probably benign |
|
|
IGL02020:Cdh7
|
APN |
1 |
110,138,348 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02135:Cdh7
|
APN |
1 |
110,138,274 (GRCm38) |
nonsense |
probably null |
|
|
IGL02285:Cdh7
|
APN |
1 |
110,138,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03237:Cdh7
|
APN |
1 |
110,138,307 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
IGL03280:Cdh7
|
APN |
1 |
110,108,768 (GRCm38) |
nonsense |
probably null |
|
|
IGL03347:Cdh7
|
APN |
1 |
110,138,243 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
IGL03385:Cdh7
|
APN |
1 |
110,065,786 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL02802:Cdh7
|
UTSW |
1 |
110,137,925 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0030:Cdh7
|
UTSW |
1 |
110,138,068 (GRCm38) |
nonsense |
probably null |
|
|
R0070:Cdh7
|
UTSW |
1 |
110,098,372 (GRCm38) |
missense |
probably benign |
0.37 |
|
R0070:Cdh7
|
UTSW |
1 |
110,098,372 (GRCm38) |
missense |
probably benign |
0.37 |
|
R0255:Cdh7
|
UTSW |
1 |
109,994,306 (GRCm38) |
missense |
probably benign |
0.09 |
|
R0365:Cdh7
|
UTSW |
1 |
110,108,756 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0506:Cdh7
|
UTSW |
1 |
110,100,114 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0549:Cdh7
|
UTSW |
1 |
110,108,944 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0599:Cdh7
|
UTSW |
1 |
110,052,966 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0648:Cdh7
|
UTSW |
1 |
110,065,607 (GRCm38) |
splice site |
probably benign |
|
|
R1033:Cdh7
|
UTSW |
1 |
110,085,053 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1173:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1174:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1175:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1403:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1403:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1406:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1406:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1587:Cdh7
|
UTSW |
1 |
110,100,027 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1728:Cdh7
|
UTSW |
1 |
110,065,735 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1729:Cdh7
|
UTSW |
1 |
110,065,735 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1730:Cdh7
|
UTSW |
1 |
110,065,735 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1739:Cdh7
|
UTSW |
1 |
110,065,735 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1762:Cdh7
|
UTSW |
1 |
110,065,735 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1769:Cdh7
|
UTSW |
1 |
110,052,876 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1783:Cdh7
|
UTSW |
1 |
110,065,735 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1785:Cdh7
|
UTSW |
1 |
110,065,735 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1940:Cdh7
|
UTSW |
1 |
110,049,024 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1972:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1973:Cdh7
|
UTSW |
1 |
110,061,132 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1997:Cdh7
|
UTSW |
1 |
110,048,938 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2060:Cdh7
|
UTSW |
1 |
110,048,877 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2068:Cdh7
|
UTSW |
1 |
110,137,936 (GRCm38) |
nonsense |
probably null |
|
|
R2137:Cdh7
|
UTSW |
1 |
110,100,106 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R2155:Cdh7
|
UTSW |
1 |
110,048,864 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3780:Cdh7
|
UTSW |
1 |
110,049,004 (GRCm38) |
missense |
probably benign |
0.45 |
|
R3781:Cdh7
|
UTSW |
1 |
110,049,004 (GRCm38) |
missense |
probably benign |
0.45 |
|
R3782:Cdh7
|
UTSW |
1 |
110,049,004 (GRCm38) |
missense |
probably benign |
0.45 |
|
R4115:Cdh7
|
UTSW |
1 |
110,138,309 (GRCm38) |
missense |
probably benign |
0.37 |
|
R4277:Cdh7
|
UTSW |
1 |
110,065,688 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4299:Cdh7
|
UTSW |
1 |
110,061,001 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4777:Cdh7
|
UTSW |
1 |
109,994,325 (GRCm38) |
nonsense |
probably null |
|
|
R4907:Cdh7
|
UTSW |
1 |
110,138,323 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5045:Cdh7
|
UTSW |
1 |
110,098,350 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5059:Cdh7
|
UTSW |
1 |
110,065,700 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5146:Cdh7
|
UTSW |
1 |
109,994,312 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R5196:Cdh7
|
UTSW |
1 |
110,138,000 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5304:Cdh7
|
UTSW |
1 |
110,108,839 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5496:Cdh7
|
UTSW |
1 |
110,048,917 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5743:Cdh7
|
UTSW |
1 |
110,108,845 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5867:Cdh7
|
UTSW |
1 |
110,048,851 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6042:Cdh7
|
UTSW |
1 |
110,138,267 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6092:Cdh7
|
UTSW |
1 |
110,098,306 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6497:Cdh7
|
UTSW |
1 |
110,065,798 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7111:Cdh7
|
UTSW |
1 |
110,137,908 (GRCm38) |
missense |
|
|
|
R7511:Cdh7
|
UTSW |
1 |
109,997,853 (GRCm38) |
intron |
probably benign |
|
|
R7532:Cdh7
|
UTSW |
1 |
110,138,159 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7879:Cdh7
|
UTSW |
1 |
110,048,947 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7978:Cdh7
|
UTSW |
1 |
109,994,105 (GRCm38) |
start gained |
probably benign |
|
|
R8022:Cdh7
|
UTSW |
1 |
110,061,108 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8207:Cdh7
|
UTSW |
1 |
109,994,346 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8224:Cdh7
|
UTSW |
1 |
109,994,203 (GRCm38) |
missense |
probably benign |
|
|
R8239:Cdh7
|
UTSW |
1 |
110,100,102 (GRCm38) |
missense |
probably benign |
0.11 |
|
R8749:Cdh7
|
UTSW |
1 |
110,099,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8884:Cdh7
|
UTSW |
1 |
110,100,130 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9030:Cdh7
|
UTSW |
1 |
110,100,113 (GRCm38) |
missense |
probably benign |
0.21 |
|
R9498:Cdh7
|
UTSW |
1 |
110,048,905 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9658:Cdh7
|
UTSW |
1 |
110,061,055 (GRCm38) |
missense |
probably damaging |
0.99 |
|
Z1088:Cdh7
|
UTSW |
1 |
110,085,123 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1176:Cdh7
|
UTSW |
1 |
110,108,736 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAAGACACAGAAGCCTTTGAC -3'
(R):5'- TTCCAAAGTAAGGGTCCAAGG -3'
Sequencing Primer
(F):5'- ACAGAAGCCTTTGACATGGC -3'
(R):5'- TTCCAAAGTAAGGGTCCAAGGCTATG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation