Incidental Mutation 'R2070:Zfp106'
| ID |
227014 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| MMRRC Submission |
040075-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2070 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
120337301-120394324 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 120354010 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Arginine
at position 1490
(H1490R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128995
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000152347]
[ENSMUST00000171215]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000055241
AA Change: H1513R
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: H1513R
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139942
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141874
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000149210
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152347
AA Change: H219R
PolyPhen 2
Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000132902
Gene: ENSMUSG00000027288
AA Change: H219R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
66 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
163 |
N/A |
INTRINSIC |
|
Pfam:WD40
|
234 |
265 |
1.3e-5 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163384
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171215
AA Change: H1490R
PolyPhen 2
Score 0.112 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000128995
Gene: ENSMUSG00000027288
AA Change: H1490R
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
20 |
44 |
7.18e1 |
SMART |
|
low complexity region
|
52 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
176 |
189 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
coiled coil region
|
777 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
1026 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1338 |
1350 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1386 |
N/A |
INTRINSIC |
|
WD40
|
1502 |
1539 |
9.24e-4 |
SMART |
|
WD40
|
1542 |
1584 |
1.83e-7 |
SMART |
|
PQQ
|
1564 |
1595 |
3.42e2 |
SMART |
|
WD40
|
1628 |
1668 |
3.45e-1 |
SMART |
|
PQQ
|
1648 |
1679 |
9.14e1 |
SMART |
|
WD40
|
1671 |
1708 |
2.12e-3 |
SMART |
|
PQQ
|
1688 |
1719 |
6.42e0 |
SMART |
|
WD40
|
1711 |
1748 |
6e-3 |
SMART |
|
PQQ
|
1728 |
1759 |
5.7e2 |
SMART |
|
WD40
|
1751 |
1788 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1795 |
1820 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1828 |
1856 |
1.31e2 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
A |
G |
11: 58,767,595 (GRCm39) |
K31E |
probably damaging |
Het |
| Abcc10 |
G |
C |
17: 46,614,491 (GRCm39) |
N1477K |
probably benign |
Het |
| Ablim2 |
G |
A |
5: 35,955,857 (GRCm39) |
C24Y |
probably damaging |
Het |
| Ankle1 |
T |
C |
8: 71,861,988 (GRCm39) |
F497S |
probably damaging |
Het |
| Armh3 |
G |
T |
19: 45,879,724 (GRCm39) |
P543Q |
probably damaging |
Het |
| Ash1l |
C |
G |
3: 88,873,510 (GRCm39) |
P98A |
probably damaging |
Het |
| Atad5 |
A |
T |
11: 79,988,878 (GRCm39) |
|
probably null |
Het |
| B3gnt4 |
A |
T |
5: 123,649,433 (GRCm39) |
H266L |
probably benign |
Het |
| Bmi1 |
A |
G |
2: 18,688,851 (GRCm39) |
I207V |
probably benign |
Het |
| Bnip3l |
A |
G |
14: 67,226,671 (GRCm39) |
M174T |
probably damaging |
Het |
| Bora |
T |
C |
14: 99,299,714 (GRCm39) |
S229P |
probably damaging |
Het |
| Ccdc121 |
T |
C |
5: 31,644,727 (GRCm39) |
V160A |
possibly damaging |
Het |
| Ccdc27 |
T |
A |
4: 154,126,270 (GRCm39) |
N73I |
unknown |
Het |
| Cdc42bpg |
T |
A |
19: 6,370,518 (GRCm39) |
C1204S |
probably damaging |
Het |
| Cdsn |
A |
T |
17: 35,865,591 (GRCm39) |
D40V |
probably damaging |
Het |
| Cilp |
T |
A |
9: 65,186,377 (GRCm39) |
V824D |
probably damaging |
Het |
| Cmtr1 |
A |
G |
17: 29,913,757 (GRCm39) |
|
probably null |
Het |
| Cntnap1 |
A |
G |
11: 101,073,805 (GRCm39) |
Y652C |
probably damaging |
Het |
| Col12a1 |
T |
C |
9: 79,554,978 (GRCm39) |
I2033M |
probably benign |
Het |
| Cwh43 |
T |
C |
5: 73,578,860 (GRCm39) |
L289P |
probably damaging |
Het |
| Ddhd1 |
T |
C |
14: 45,848,081 (GRCm39) |
D529G |
probably damaging |
Het |
| Defb28 |
T |
A |
2: 152,362,064 (GRCm39) |
S75T |
probably benign |
Het |
| Dennd2a |
A |
T |
6: 39,442,053 (GRCm39) |
V939D |
probably damaging |
Het |
| Dlg5 |
T |
C |
14: 24,186,703 (GRCm39) |
R1866G |
probably damaging |
Het |
| Dsc1 |
C |
T |
18: 20,221,353 (GRCm39) |
|
probably null |
Het |
| Ecscr |
T |
G |
18: 35,848,490 (GRCm39) |
N184T |
probably damaging |
Het |
| Eif4ebp1 |
G |
T |
8: 27,763,372 (GRCm39) |
R55L |
probably damaging |
Het |
| Eml1 |
G |
T |
12: 108,479,258 (GRCm39) |
V344L |
probably damaging |
Het |
| Exoc2 |
G |
T |
13: 30,999,353 (GRCm39) |
N901K |
probably benign |
Het |
| Fam161b |
T |
A |
12: 84,403,202 (GRCm39) |
I143F |
probably benign |
Het |
| Fam180a |
A |
G |
6: 35,302,846 (GRCm39) |
S2P |
probably benign |
Het |
| Fat3 |
T |
A |
9: 15,910,666 (GRCm39) |
I1779F |
probably benign |
Het |
| Fat4 |
A |
G |
3: 39,064,804 (GRCm39) |
K4920R |
probably benign |
Het |
| Fsip2 |
T |
A |
2: 82,806,699 (GRCm39) |
V1006E |
probably damaging |
Het |
| Glcci1 |
A |
G |
6: 8,558,566 (GRCm39) |
S30G |
probably damaging |
Het |
| Gm5414 |
A |
T |
15: 101,536,495 (GRCm39) |
S43R |
possibly damaging |
Het |
| Hao1 |
T |
C |
2: 134,372,535 (GRCm39) |
T158A |
probably damaging |
Het |
| Hic1 |
T |
C |
11: 75,059,885 (GRCm39) |
H154R |
possibly damaging |
Het |
| Hmgxb3 |
T |
C |
18: 61,304,431 (GRCm39) |
Y53C |
probably damaging |
Het |
| Ipmk |
A |
T |
10: 71,208,579 (GRCm39) |
K122* |
probably null |
Het |
| Jakmip2 |
T |
C |
18: 43,696,395 (GRCm39) |
E518G |
probably benign |
Het |
| Kmt2e |
A |
G |
5: 23,706,993 (GRCm39) |
T1519A |
probably benign |
Het |
| Lfng |
T |
C |
5: 140,598,350 (GRCm39) |
I224T |
possibly damaging |
Het |
| Magel2 |
G |
A |
7: 62,028,844 (GRCm39) |
V583I |
unknown |
Het |
| Map4k5 |
C |
T |
12: 69,863,111 (GRCm39) |
V629I |
probably damaging |
Het |
| Med12l |
A |
G |
3: 59,152,326 (GRCm39) |
D1037G |
probably damaging |
Het |
| Morc1 |
C |
T |
16: 48,412,974 (GRCm39) |
T705I |
probably benign |
Het |
| Mptx2 |
A |
T |
1: 173,102,145 (GRCm39) |
Y181* |
probably null |
Het |
| Mrpl24 |
T |
C |
3: 87,830,374 (GRCm39) |
|
probably null |
Het |
| Myo5a |
A |
G |
9: 75,089,266 (GRCm39) |
E1132G |
probably benign |
Het |
| Nedd4l |
T |
G |
18: 65,345,891 (GRCm39) |
F814L |
probably damaging |
Het |
| Nmral1 |
T |
A |
16: 4,534,211 (GRCm39) |
I77F |
probably damaging |
Het |
| Oit3 |
T |
G |
10: 59,266,835 (GRCm39) |
I224L |
probably benign |
Het |
| Oxsm |
A |
G |
14: 16,241,983 (GRCm38) |
L262P |
probably benign |
Het |
| Pacs2 |
C |
T |
12: 113,024,731 (GRCm39) |
T407I |
probably damaging |
Het |
| Pard6g |
T |
C |
18: 80,160,940 (GRCm39) |
I351T |
probably benign |
Het |
| Pdcl2 |
A |
T |
5: 76,472,838 (GRCm39) |
|
probably null |
Het |
| Pdzph1 |
T |
C |
17: 59,281,092 (GRCm39) |
R397G |
probably benign |
Het |
| Phip |
T |
A |
9: 82,757,352 (GRCm39) |
I1607L |
probably benign |
Het |
| Plekhd1 |
C |
A |
12: 80,739,681 (GRCm39) |
S10* |
probably null |
Het |
| Pramel24 |
T |
G |
4: 143,453,472 (GRCm39) |
Y193* |
probably null |
Het |
| Prdm1 |
C |
T |
10: 44,317,408 (GRCm39) |
D505N |
possibly damaging |
Het |
| Psmd13 |
T |
C |
7: 140,477,561 (GRCm39) |
V320A |
probably damaging |
Het |
| Rbak |
A |
G |
5: 143,162,339 (GRCm39) |
L8P |
probably damaging |
Het |
| Rere |
C |
A |
4: 150,699,047 (GRCm39) |
|
probably benign |
Het |
| Rint1 |
T |
C |
5: 24,015,927 (GRCm39) |
S456P |
possibly damaging |
Het |
| Scn3a |
T |
C |
2: 65,351,210 (GRCm39) |
Q446R |
possibly damaging |
Het |
| Slitrk5 |
A |
G |
14: 111,917,621 (GRCm39) |
Y415C |
probably damaging |
Het |
| Snrnp200 |
A |
G |
2: 127,054,323 (GRCm39) |
E210G |
possibly damaging |
Het |
| Snrnp200 |
A |
G |
2: 127,079,803 (GRCm39) |
T1891A |
probably benign |
Het |
| Sohlh2 |
A |
G |
3: 55,115,043 (GRCm39) |
I343V |
probably benign |
Het |
| Spin1 |
T |
C |
13: 51,298,573 (GRCm39) |
|
probably null |
Het |
| St14 |
T |
A |
9: 31,002,669 (GRCm39) |
I745F |
probably damaging |
Het |
| Sv2a |
G |
A |
3: 96,101,191 (GRCm39) |
A730T |
possibly damaging |
Het |
| Tars2 |
C |
A |
3: 95,654,950 (GRCm39) |
G113C |
probably damaging |
Het |
| Tlcd3b |
T |
C |
7: 126,419,012 (GRCm39) |
L4P |
probably benign |
Het |
| Trp53 |
A |
G |
11: 69,480,458 (GRCm39) |
D278G |
probably damaging |
Het |
| Ubxn7 |
T |
A |
16: 32,191,287 (GRCm39) |
C160S |
possibly damaging |
Het |
| Uty |
T |
C |
Y: 1,169,193 (GRCm39) |
E414G |
probably benign |
Het |
| Wrap73 |
T |
A |
4: 154,233,200 (GRCm39) |
S125T |
possibly damaging |
Het |
| Wwc2 |
T |
C |
8: 48,321,356 (GRCm39) |
D586G |
unknown |
Het |
| Zswim5 |
T |
C |
4: 116,837,109 (GRCm39) |
V731A |
probably benign |
Het |
| Zyg11b |
G |
C |
4: 108,108,016 (GRCm39) |
N463K |
possibly damaging |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,369,978 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,344,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,343,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,365,516 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,354,945 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,354,034 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,355,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,365,288 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,369,803 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,354,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,364,712 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,376,395 (GRCm39) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,340,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,362,178 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,359,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,354,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,365,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,350,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,364,356 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,358,953 (GRCm39) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,362,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,357,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Zfp106
|
UTSW |
2 |
120,385,729 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0828:Zfp106
|
UTSW |
2 |
120,366,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,365,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,354,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,364,245 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1754:Zfp106
|
UTSW |
2 |
120,364,244 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1755:Zfp106
|
UTSW |
2 |
120,365,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,350,909 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,344,096 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,362,162 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2301:Zfp106
|
UTSW |
2 |
120,366,131 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,357,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,365,080 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,365,094 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,362,630 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,364,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,365,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,357,380 (GRCm39) |
splice site |
probably null |
|
|
R4678:Zfp106
|
UTSW |
2 |
120,364,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4965:Zfp106
|
UTSW |
2 |
120,364,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5011:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,365,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,354,449 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5328:Zfp106
|
UTSW |
2 |
120,350,898 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5403:Zfp106
|
UTSW |
2 |
120,365,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,362,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,363,988 (GRCm39) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,354,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,346,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,353,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,364,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,369,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,362,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,376,400 (GRCm39) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,341,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,343,215 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,354,538 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,366,096 (GRCm39) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,344,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,355,000 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,354,812 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,354,600 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,366,077 (GRCm39) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,364,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Zfp106
|
UTSW |
2 |
120,369,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,350,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,364,812 (GRCm39) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,353,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,351,007 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,365,807 (GRCm39) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,365,297 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,360,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGACAGGAGTGTGCAACGTG -3'
(R):5'- AAATCTTGGCTCTTGGAGTCG -3'
Sequencing Primer
(F):5'- CAACGTGCAAAGCCCAGGG -3'
(R):5'- GCTCTTGGAGTCGGCTTG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation