Incidental Mutation 'R2072:Dlgap1'
| ID |
227276 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dlgap1
|
| Ensembl Gene |
ENSMUSG00000003279 |
| Gene Name |
DLG associated protein 1 |
| Synonyms |
Sapap1, Gkap, GKAP/SAPAP, SAPAP1, D17Bwg0511e, DAP-1 beta, 4933422O14Rik |
| MMRRC Submission |
040077-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2072 (G1)
|
| Quality Score |
174 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
70276068-71128408 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 70969765 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Cysteine
at position 524
(R524C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000116072
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000060072]
[ENSMUST00000097288]
[ENSMUST00000133717]
[ENSMUST00000133983]
[ENSMUST00000135938]
[ENSMUST00000140728]
[ENSMUST00000155016]
[ENSMUST00000148486]
[ENSMUST00000146730]
|
| AlphaFold |
Q9D415 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000060072
AA Change: R524C
PolyPhen 2
Score 0.931 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000052858
Gene: ENSMUSG00000003279
AA Change: R524C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
180 |
210 |
N/A |
INTRINSIC |
|
low complexity region
|
515 |
539 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
642 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
643 |
982 |
6.8e-139 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000097288
AA Change: R216C
PolyPhen 2
Score 0.923 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000094890
Gene: ENSMUSG00000003279
AA Change: R216C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
208 |
228 |
N/A |
INTRINSIC |
|
low complexity region
|
244 |
261 |
N/A |
INTRINSIC |
|
low complexity region
|
330 |
344 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
345 |
625 |
9.4e-106 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126801
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000133717
AA Change: R226C
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000122370
Gene: ENSMUSG00000003279
AA Change: R226C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
218 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
312 |
326 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
327 |
666 |
1.3e-139 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000133983
AA Change: R524C
PolyPhen 2
Score 0.931 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000116716
Gene: ENSMUSG00000003279
AA Change: R524C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
180 |
210 |
N/A |
INTRINSIC |
|
low complexity region
|
515 |
539 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
642 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
643 |
982 |
6.8e-139 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000135938
AA Change: R524C
PolyPhen 2
Score 0.931 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000118497
Gene: ENSMUSG00000003279
AA Change: R524C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
180 |
210 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
536 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
624 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
625 |
964 |
9.3e-139 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140728
AA Change: R224C
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000117358
Gene: ENSMUSG00000003279
AA Change: R224C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
216 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
252 |
269 |
N/A |
INTRINSIC |
|
low complexity region
|
338 |
352 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
353 |
692 |
1.4e-139 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000155016
AA Change: R524C
PolyPhen 2
Score 0.931 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000122896
Gene: ENSMUSG00000003279
AA Change: R524C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
180 |
210 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
536 |
N/A |
INTRINSIC |
|
low complexity region
|
552 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
652 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
660 |
992 |
2e-153 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000148486
AA Change: R224C
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000122337
Gene: ENSMUSG00000003279
AA Change: R224C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
215 |
239 |
N/A |
INTRINSIC |
|
low complexity region
|
242 |
259 |
N/A |
INTRINSIC |
|
low complexity region
|
328 |
342 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
343 |
682 |
1.3e-139 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000146730
AA Change: R524C
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000116072
Gene: ENSMUSG00000003279
AA Change: R524C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
180 |
210 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
536 |
N/A |
INTRINSIC |
|
low complexity region
|
552 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
652 |
N/A |
INTRINSIC |
|
Pfam:GKAP
|
653 |
933 |
9.5e-106 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150260
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150798
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.3%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 0610040J01Rik |
G |
C |
5: 64,056,080 (GRCm39) |
R272P |
possibly damaging |
Het |
| Ablim3 |
A |
T |
18: 61,990,159 (GRCm39) |
D83E |
possibly damaging |
Het |
| Aco1 |
G |
A |
4: 40,183,605 (GRCm39) |
G508S |
probably damaging |
Het |
| Adamts13 |
C |
A |
2: 26,895,437 (GRCm39) |
T1176N |
probably benign |
Het |
| Adgre5 |
T |
C |
8: 84,454,433 (GRCm39) |
T357A |
probably benign |
Het |
| Akap8l |
C |
T |
17: 32,551,457 (GRCm39) |
R511H |
probably damaging |
Het |
| Ankrd33 |
T |
C |
15: 101,017,517 (GRCm39) |
V310A |
probably benign |
Het |
| Armh3 |
A |
T |
19: 45,953,820 (GRCm39) |
I188K |
probably damaging |
Het |
| Bnipl |
C |
T |
3: 95,151,522 (GRCm39) |
G232E |
probably damaging |
Het |
| Btbd17 |
A |
T |
11: 114,682,778 (GRCm39) |
|
probably null |
Het |
| Cacna1s |
G |
A |
1: 136,007,242 (GRCm39) |
V173I |
probably benign |
Het |
| Ccdc122 |
T |
C |
14: 77,306,391 (GRCm39) |
|
probably null |
Het |
| Ces1a |
T |
A |
8: 93,774,703 (GRCm39) |
N12Y |
probably benign |
Het |
| Chrdl1 |
T |
C |
X: 142,086,414 (GRCm39) |
I231V |
probably benign |
Het |
| Ciita |
C |
T |
16: 10,336,217 (GRCm39) |
T958I |
probably benign |
Het |
| Cnot1 |
G |
T |
8: 96,466,461 (GRCm39) |
T1592K |
possibly damaging |
Het |
| Dcaf15 |
T |
C |
8: 84,828,370 (GRCm39) |
D240G |
probably damaging |
Het |
| Dmd |
G |
C |
X: 83,356,089 (GRCm39) |
A2257P |
probably benign |
Het |
| Dsg1c |
A |
G |
18: 20,408,309 (GRCm39) |
M453V |
probably benign |
Het |
| Ednrb |
G |
T |
14: 104,054,535 (GRCm39) |
N432K |
probably benign |
Het |
| Fcgbp |
G |
A |
7: 27,819,814 (GRCm39) |
G2514S |
probably damaging |
Het |
| Fez1 |
A |
G |
9: 36,779,241 (GRCm39) |
K306R |
probably benign |
Het |
| Fmo4 |
A |
G |
1: 162,637,456 (GRCm39) |
V12A |
probably benign |
Het |
| Fpgt |
T |
C |
3: 154,793,511 (GRCm39) |
Y172C |
probably damaging |
Het |
| Fsip2 |
T |
A |
2: 82,839,159 (GRCm39) |
F6976I |
possibly damaging |
Het |
| Galnt12 |
C |
T |
4: 47,108,477 (GRCm39) |
R205* |
probably null |
Het |
| Grik5 |
A |
T |
7: 24,714,738 (GRCm39) |
M752K |
possibly damaging |
Het |
| Herc2 |
A |
G |
7: 55,876,712 (GRCm39) |
N4516S |
probably damaging |
Het |
| Ifrd2 |
A |
T |
9: 107,469,744 (GRCm39) |
D439V |
probably damaging |
Het |
| Igsf3 |
A |
G |
3: 101,346,831 (GRCm39) |
T609A |
probably benign |
Het |
| Kif5a |
T |
C |
10: 127,081,238 (GRCm39) |
D232G |
probably damaging |
Het |
| Lgi2 |
A |
G |
5: 52,695,847 (GRCm39) |
S371P |
probably damaging |
Het |
| Marchf3 |
A |
T |
18: 56,944,925 (GRCm39) |
V56E |
possibly damaging |
Het |
| Mib2 |
T |
C |
4: 155,744,158 (GRCm39) |
D168G |
probably damaging |
Het |
| Nhs |
T |
A |
X: 160,625,717 (GRCm39) |
H544L |
probably damaging |
Het |
| Nlrp2 |
A |
G |
7: 5,328,005 (GRCm39) |
S683P |
probably damaging |
Het |
| Onecut3 |
T |
G |
10: 80,330,848 (GRCm39) |
L3V |
unknown |
Het |
| Or12j2 |
T |
C |
7: 139,916,566 (GRCm39) |
S264P |
possibly damaging |
Het |
| Or4c35 |
C |
A |
2: 89,808,557 (GRCm39) |
T145K |
probably benign |
Het |
| Or5b102 |
A |
T |
19: 13,041,044 (GRCm39) |
M90L |
probably benign |
Het |
| Otogl |
C |
T |
10: 107,616,904 (GRCm39) |
C1791Y |
probably damaging |
Het |
| Paip1 |
T |
C |
13: 119,566,798 (GRCm39) |
V128A |
possibly damaging |
Het |
| Pcnx2 |
A |
T |
8: 126,488,481 (GRCm39) |
C1688S |
possibly damaging |
Het |
| Pdzd2 |
A |
G |
15: 12,385,905 (GRCm39) |
L955P |
probably damaging |
Het |
| Phlpp2 |
T |
C |
8: 110,655,124 (GRCm39) |
S605P |
possibly damaging |
Het |
| Pkhd1l1 |
G |
T |
15: 44,422,035 (GRCm39) |
A3102S |
probably damaging |
Het |
| Plxnb2 |
G |
T |
15: 89,042,654 (GRCm39) |
R1545S |
probably damaging |
Het |
| Ppp4c |
T |
C |
7: 126,386,520 (GRCm39) |
|
probably null |
Het |
| Prune1 |
C |
T |
3: 95,162,719 (GRCm39) |
R318Q |
probably benign |
Het |
| Psg27 |
T |
C |
7: 18,294,342 (GRCm39) |
D355G |
probably damaging |
Het |
| Psg27 |
A |
G |
7: 18,298,934 (GRCm39) |
L129P |
probably benign |
Het |
| Psmc6 |
A |
G |
14: 45,567,323 (GRCm39) |
K7E |
possibly damaging |
Het |
| Reln |
A |
T |
5: 22,124,175 (GRCm39) |
V2777E |
probably damaging |
Het |
| Rigi |
A |
T |
4: 40,224,069 (GRCm39) |
|
probably null |
Het |
| Scn11a |
G |
T |
9: 119,640,274 (GRCm39) |
A207E |
possibly damaging |
Het |
| Slc5a5 |
C |
T |
8: 71,345,083 (GRCm39) |
G75R |
possibly damaging |
Het |
| Smarcd2 |
A |
T |
11: 106,156,133 (GRCm39) |
L42* |
probably null |
Het |
| Smg1 |
T |
C |
7: 117,762,389 (GRCm39) |
|
probably benign |
Het |
| Smurf2 |
T |
A |
11: 106,732,595 (GRCm39) |
Q335L |
probably benign |
Het |
| Sspo |
A |
T |
6: 48,450,451 (GRCm39) |
H2580L |
probably benign |
Het |
| Stk3 |
T |
C |
15: 34,959,195 (GRCm39) |
M256V |
possibly damaging |
Het |
| Syt1 |
A |
G |
10: 108,419,833 (GRCm39) |
I276T |
probably damaging |
Het |
| Syt10 |
C |
T |
15: 89,674,979 (GRCm39) |
D456N |
probably damaging |
Het |
| Taar9 |
A |
T |
10: 23,984,877 (GRCm39) |
C186S |
probably damaging |
Het |
| Tnrc6b |
C |
T |
15: 80,767,166 (GRCm39) |
P977L |
possibly damaging |
Het |
| Trp53bp2 |
A |
G |
1: 182,286,432 (GRCm39) |
T1091A |
probably benign |
Het |
| Ttn |
G |
T |
2: 76,768,120 (GRCm39) |
T2947N |
probably damaging |
Het |
| Ube2q1 |
T |
C |
3: 89,686,878 (GRCm39) |
|
probably null |
Het |
| Ube3c |
A |
G |
5: 29,840,638 (GRCm39) |
E671G |
probably benign |
Het |
| Upf3a |
A |
G |
8: 13,835,850 (GRCm39) |
K56R |
possibly damaging |
Het |
| Vmn2r15 |
A |
T |
5: 109,434,619 (GRCm39) |
M695K |
possibly damaging |
Het |
| Vmn2r3 |
A |
T |
3: 64,182,493 (GRCm39) |
M402K |
possibly damaging |
Het |
| Zfp354b |
T |
A |
11: 50,813,279 (GRCm39) |
R549* |
probably null |
Het |
| Zfp37 |
A |
T |
4: 62,109,945 (GRCm39) |
M411K |
probably damaging |
Het |
| Zfp747 |
T |
A |
7: 126,973,142 (GRCm39) |
T343S |
possibly damaging |
Het |
| Zfp853 |
T |
A |
5: 143,275,137 (GRCm39) |
Q161L |
unknown |
Het |
|
| Other mutations in Dlgap1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00162:Dlgap1
|
APN |
17 |
70,823,080 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01413:Dlgap1
|
APN |
17 |
70,823,069 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01531:Dlgap1
|
APN |
17 |
70,823,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02226:Dlgap1
|
APN |
17 |
70,823,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB009:Dlgap1
|
UTSW |
17 |
70,823,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB019:Dlgap1
|
UTSW |
17 |
70,823,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0453:Dlgap1
|
UTSW |
17 |
71,068,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0482:Dlgap1
|
UTSW |
17 |
70,823,185 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0520:Dlgap1
|
UTSW |
17 |
70,823,989 (GRCm39) |
nonsense |
probably null |
|
|
R1951:Dlgap1
|
UTSW |
17 |
71,068,306 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2076:Dlgap1
|
UTSW |
17 |
71,093,826 (GRCm39) |
nonsense |
probably null |
|
|
R3438:Dlgap1
|
UTSW |
17 |
70,823,356 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3743:Dlgap1
|
UTSW |
17 |
71,025,221 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3881:Dlgap1
|
UTSW |
17 |
71,093,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3981:Dlgap1
|
UTSW |
17 |
70,823,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4043:Dlgap1
|
UTSW |
17 |
71,068,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4272:Dlgap1
|
UTSW |
17 |
71,073,038 (GRCm39) |
missense |
probably benign |
|
|
R4273:Dlgap1
|
UTSW |
17 |
71,073,038 (GRCm39) |
missense |
probably benign |
|
|
R4557:Dlgap1
|
UTSW |
17 |
70,823,684 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4652:Dlgap1
|
UTSW |
17 |
71,068,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4771:Dlgap1
|
UTSW |
17 |
70,900,375 (GRCm39) |
nonsense |
probably null |
|
|
R5000:Dlgap1
|
UTSW |
17 |
71,073,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5004:Dlgap1
|
UTSW |
17 |
71,025,222 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5291:Dlgap1
|
UTSW |
17 |
71,025,205 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5304:Dlgap1
|
UTSW |
17 |
71,122,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5473:Dlgap1
|
UTSW |
17 |
70,824,025 (GRCm39) |
intron |
probably benign |
|
|
R5522:Dlgap1
|
UTSW |
17 |
70,823,993 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5586:Dlgap1
|
UTSW |
17 |
71,125,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5742:Dlgap1
|
UTSW |
17 |
71,025,194 (GRCm39) |
missense |
probably benign |
|
|
R5802:Dlgap1
|
UTSW |
17 |
71,073,086 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5850:Dlgap1
|
UTSW |
17 |
71,094,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5857:Dlgap1
|
UTSW |
17 |
71,122,388 (GRCm39) |
intron |
probably benign |
|
|
R5883:Dlgap1
|
UTSW |
17 |
70,824,008 (GRCm39) |
intron |
probably benign |
|
|
R6045:Dlgap1
|
UTSW |
17 |
71,125,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6336:Dlgap1
|
UTSW |
17 |
71,122,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6448:Dlgap1
|
UTSW |
17 |
70,900,325 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6682:Dlgap1
|
UTSW |
17 |
71,094,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6795:Dlgap1
|
UTSW |
17 |
71,125,069 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7147:Dlgap1
|
UTSW |
17 |
70,969,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7187:Dlgap1
|
UTSW |
17 |
70,823,093 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7382:Dlgap1
|
UTSW |
17 |
71,094,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7859:Dlgap1
|
UTSW |
17 |
70,823,683 (GRCm39) |
missense |
probably benign |
|
|
R7932:Dlgap1
|
UTSW |
17 |
70,823,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8477:Dlgap1
|
UTSW |
17 |
70,823,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Dlgap1
|
UTSW |
17 |
71,122,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8866:Dlgap1
|
UTSW |
17 |
70,823,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8910:Dlgap1
|
UTSW |
17 |
71,093,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8997:Dlgap1
|
UTSW |
17 |
70,823,528 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9012:Dlgap1
|
UTSW |
17 |
70,823,182 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9035:Dlgap1
|
UTSW |
17 |
70,823,855 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9067:Dlgap1
|
UTSW |
17 |
71,116,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9361:Dlgap1
|
UTSW |
17 |
71,068,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9464:Dlgap1
|
UTSW |
17 |
70,823,964 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9550:Dlgap1
|
UTSW |
17 |
71,093,902 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9564:Dlgap1
|
UTSW |
17 |
70,964,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9565:Dlgap1
|
UTSW |
17 |
70,964,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
T0975:Dlgap1
|
UTSW |
17 |
70,823,950 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1176:Dlgap1
|
UTSW |
17 |
71,122,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Dlgap1
|
UTSW |
17 |
70,969,738 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTTCGAATCCGTGTGCGAG -3'
(R):5'- CCTGTGGATTCTCACATGGTGG -3'
Sequencing Primer
(F):5'- CGAGTCTGTGTTCAGCGAGC -3'
(R):5'- ATTCTCACATGGTGGTGGAG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation