Incidental Mutation 'R2131:Arap2'
| ID |
228060 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap2
|
| Ensembl Gene |
ENSMUSG00000037999 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| Synonyms |
Centd1 |
| MMRRC Submission |
040134-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2131 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
62759788-62923502 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 62835301 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 747
(N747S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076623]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076623
AA Change: N747S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000075924
Gene: ENSMUSG00000037999
AA Change: N747S
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
low complexity region
|
222 |
233 |
N/A |
INTRINSIC |
|
PH
|
481 |
574 |
6.45e-17 |
SMART |
|
PH
|
586 |
679 |
9.05e-12 |
SMART |
|
ArfGap
|
684 |
805 |
9.2e-33 |
SMART |
|
PH
|
891 |
1003 |
1.51e-8 |
SMART |
|
PH
|
1013 |
1112 |
9.21e-4 |
SMART |
|
RhoGAP
|
1124 |
1300 |
1.36e-50 |
SMART |
|
Pfam:RA
|
1325 |
1416 |
2.1e-7 |
PFAM |
|
PH
|
1429 |
1533 |
2.68e-14 |
SMART |
|
coiled coil region
|
1561 |
1590 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201373
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 123 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2ml1 |
T |
A |
6: 128,553,223 (GRCm39) |
N178I |
probably damaging |
Het |
| Acvr2b |
A |
G |
9: 119,261,874 (GRCm39) |
R437G |
probably damaging |
Het |
| Adamtsl3 |
C |
A |
7: 82,227,802 (GRCm39) |
A1329E |
probably damaging |
Het |
| Adgrl2 |
T |
C |
3: 148,596,124 (GRCm39) |
I71V |
probably damaging |
Het |
| Adra1a |
A |
T |
14: 66,964,981 (GRCm39) |
I324F |
possibly damaging |
Het |
| Akap13 |
G |
T |
7: 75,261,182 (GRCm39) |
A1269S |
probably benign |
Het |
| Ampd1 |
G |
T |
3: 103,002,194 (GRCm39) |
|
probably null |
Het |
| Ankrd16 |
T |
A |
2: 11,788,506 (GRCm39) |
D211E |
probably damaging |
Het |
| Aopep |
T |
A |
13: 63,357,963 (GRCm39) |
C656S |
probably benign |
Het |
| Aox3 |
A |
G |
1: 58,209,002 (GRCm39) |
H845R |
probably damaging |
Het |
| Apc |
C |
A |
18: 34,445,098 (GRCm39) |
Q665K |
possibly damaging |
Het |
| Arsk |
A |
T |
13: 76,239,931 (GRCm39) |
C47* |
probably null |
Het |
| Atp8b5 |
T |
A |
4: 43,370,726 (GRCm39) |
F1001I |
probably benign |
Het |
| Bap1 |
T |
A |
14: 30,980,288 (GRCm39) |
Y645* |
probably null |
Het |
| Brca2 |
A |
G |
5: 150,480,594 (GRCm39) |
Y2760C |
probably damaging |
Het |
| Cad |
T |
A |
5: 31,215,416 (GRCm39) |
F76I |
probably damaging |
Het |
| Capn9 |
G |
A |
8: 125,332,450 (GRCm39) |
G430R |
possibly damaging |
Het |
| Castor2 |
G |
A |
5: 134,164,992 (GRCm39) |
C187Y |
probably damaging |
Het |
| Ccdc27 |
TTCCTCCTCCTCCTCCTCCTC |
TTCCTCCTCCTCCTCCTC |
4: 154,120,763 (GRCm39) |
|
probably benign |
Het |
| Cdkn2c |
A |
C |
4: 109,522,260 (GRCm39) |
N28K |
probably null |
Het |
| Celsr1 |
T |
A |
15: 85,847,424 (GRCm39) |
I1438F |
probably benign |
Het |
| Cfhr2 |
T |
G |
1: 139,758,893 (GRCm39) |
R52S |
probably benign |
Het |
| Cldn1 |
G |
C |
16: 26,190,300 (GRCm39) |
A26G |
probably damaging |
Het |
| Col20a1 |
T |
A |
2: 180,634,366 (GRCm39) |
F110L |
probably damaging |
Het |
| Creg2 |
T |
C |
1: 39,664,146 (GRCm39) |
N204S |
probably benign |
Het |
| Cx3cl1 |
C |
A |
8: 95,506,201 (GRCm39) |
Q69K |
probably benign |
Het |
| Cyfip2 |
T |
C |
11: 46,176,958 (GRCm39) |
E74G |
possibly damaging |
Het |
| Cyp2g1 |
A |
T |
7: 26,520,135 (GRCm39) |
I456F |
probably damaging |
Het |
| Dapk1 |
T |
A |
13: 60,909,481 (GRCm39) |
W1365R |
possibly damaging |
Het |
| Dapk1 |
A |
G |
13: 60,877,345 (GRCm39) |
E528G |
possibly damaging |
Het |
| Dbt |
T |
A |
3: 116,332,773 (GRCm39) |
D16E |
probably damaging |
Het |
| Depdc5 |
T |
A |
5: 33,148,125 (GRCm39) |
L1469* |
probably null |
Het |
| Dnah3 |
T |
A |
7: 119,566,982 (GRCm39) |
T2415S |
possibly damaging |
Het |
| Dnmbp |
A |
G |
19: 43,842,750 (GRCm39) |
L1210S |
probably damaging |
Het |
| Dpyd |
T |
C |
3: 118,468,217 (GRCm39) |
V77A |
probably benign |
Het |
| Eps15l1 |
A |
T |
8: 73,140,712 (GRCm39) |
V260D |
probably benign |
Het |
| Eya1 |
A |
G |
1: 14,241,198 (GRCm39) |
V573A |
probably benign |
Het |
| Fam171b |
T |
A |
2: 83,710,202 (GRCm39) |
S625T |
probably damaging |
Het |
| Fam186a |
T |
C |
15: 99,831,557 (GRCm39) |
|
probably benign |
Het |
| Gabra4 |
G |
T |
5: 71,798,567 (GRCm39) |
D137E |
probably benign |
Het |
| Gemin4 |
G |
C |
11: 76,101,876 (GRCm39) |
P962A |
probably damaging |
Het |
| Gm43302 |
T |
C |
5: 105,422,610 (GRCm39) |
D474G |
probably damaging |
Het |
| Golim4 |
A |
T |
3: 75,815,456 (GRCm39) |
V116D |
probably damaging |
Het |
| Gpr19 |
T |
C |
6: 134,847,405 (GRCm39) |
M1V |
probably null |
Het |
| Hnf4a |
T |
A |
2: 163,389,338 (GRCm39) |
N29K |
probably benign |
Het |
| Htt |
A |
G |
5: 35,034,453 (GRCm39) |
R1975G |
possibly damaging |
Het |
| Ift20 |
G |
A |
11: 78,430,860 (GRCm39) |
E68K |
probably damaging |
Het |
| Il4i1 |
G |
A |
7: 44,489,494 (GRCm39) |
V420M |
probably damaging |
Het |
| Insrr |
G |
A |
3: 87,717,879 (GRCm39) |
|
probably null |
Het |
| Ipo9 |
ATCCTCCTCCTCCTCCTC |
ATCCTCCTCCTCCTCCTCCTC |
1: 135,314,006 (GRCm39) |
|
probably benign |
Het |
| Ipo9 |
A |
G |
1: 135,329,988 (GRCm39) |
V484A |
probably benign |
Het |
| Jmjd4 |
A |
T |
11: 59,345,781 (GRCm39) |
H287L |
probably damaging |
Het |
| Kcnj13 |
A |
G |
1: 87,314,256 (GRCm39) |
V322A |
probably benign |
Het |
| Kdm5d |
T |
C |
Y: 941,483 (GRCm39) |
L1228P |
probably benign |
Het |
| Klra3 |
A |
G |
6: 130,312,738 (GRCm39) |
S9P |
probably benign |
Het |
| Ldhd |
C |
T |
8: 112,355,169 (GRCm39) |
|
probably null |
Het |
| Lmo2 |
T |
C |
2: 103,811,407 (GRCm39) |
Y147H |
probably damaging |
Het |
| Lmo7 |
A |
T |
14: 102,137,674 (GRCm39) |
D670V |
probably damaging |
Het |
| Lmtk2 |
C |
T |
5: 144,111,806 (GRCm39) |
T842I |
possibly damaging |
Het |
| Lrp5 |
T |
C |
19: 3,672,708 (GRCm39) |
T534A |
possibly damaging |
Het |
| Lrrc24 |
A |
T |
15: 76,599,781 (GRCm39) |
F453I |
possibly damaging |
Het |
| Magel2 |
A |
T |
7: 62,027,486 (GRCm39) |
H130L |
unknown |
Het |
| Mcpt8 |
T |
C |
14: 56,319,740 (GRCm39) |
I237V |
probably damaging |
Het |
| Med4 |
A |
G |
14: 73,755,436 (GRCm39) |
N248S |
possibly damaging |
Het |
| Mest |
C |
T |
6: 30,745,884 (GRCm39) |
L269F |
probably damaging |
Het |
| Mib2 |
C |
T |
4: 155,739,695 (GRCm39) |
|
probably null |
Het |
| Mki67 |
T |
A |
7: 135,305,970 (GRCm39) |
|
probably null |
Het |
| Mnx1 |
T |
A |
5: 29,679,187 (GRCm39) |
S299C |
unknown |
Het |
| Nbr1 |
T |
A |
11: 101,457,017 (GRCm39) |
|
probably null |
Het |
| Ncapd3 |
T |
G |
9: 26,994,642 (GRCm39) |
V1174G |
probably damaging |
Het |
| Nyap1 |
A |
C |
5: 137,731,943 (GRCm39) |
|
probably null |
Het |
| Olfml3 |
T |
A |
3: 103,643,185 (GRCm39) |
M399L |
probably benign |
Het |
| Oosp1 |
T |
C |
19: 11,668,314 (GRCm39) |
D23G |
probably damaging |
Het |
| Optc |
A |
T |
1: 133,831,534 (GRCm39) |
|
probably null |
Het |
| Or1j13 |
A |
G |
2: 36,370,059 (GRCm39) |
S28P |
possibly damaging |
Het |
| Or6c205 |
T |
C |
10: 129,086,943 (GRCm39) |
F180S |
probably benign |
Het |
| Osbpl6 |
T |
A |
2: 76,416,558 (GRCm39) |
I546K |
probably damaging |
Het |
| Otog |
A |
T |
7: 45,899,524 (GRCm39) |
N275I |
probably damaging |
Het |
| Pcdhb14 |
C |
A |
18: 37,580,923 (GRCm39) |
Q10K |
probably benign |
Het |
| Pcx |
T |
C |
19: 4,652,579 (GRCm39) |
F189L |
probably benign |
Het |
| Pde6b |
A |
G |
5: 108,576,069 (GRCm39) |
D718G |
probably damaging |
Het |
| Pklr |
C |
A |
3: 89,049,967 (GRCm39) |
P314Q |
probably damaging |
Het |
| Plcb1 |
T |
A |
2: 135,167,587 (GRCm39) |
Y460* |
probably null |
Het |
| Plekha6 |
C |
A |
1: 133,207,103 (GRCm39) |
|
probably null |
Het |
| Plekho1 |
A |
G |
3: 95,896,429 (GRCm39) |
S347P |
probably damaging |
Het |
| Plxna2 |
G |
A |
1: 194,327,058 (GRCm39) |
D331N |
probably benign |
Het |
| Prelp |
C |
T |
1: 133,842,869 (GRCm39) |
R92K |
probably benign |
Het |
| Prkra |
A |
T |
2: 76,477,480 (GRCm39) |
I75K |
probably damaging |
Het |
| Ptpn11 |
G |
A |
5: 121,310,089 (GRCm39) |
A31V |
probably damaging |
Het |
| Pzp |
T |
C |
6: 128,468,124 (GRCm39) |
|
probably null |
Het |
| Rbm12 |
A |
T |
2: 155,937,430 (GRCm39) |
C947* |
probably null |
Het |
| Ren1 |
C |
G |
1: 133,278,516 (GRCm39) |
|
probably null |
Het |
| Ro60 |
T |
C |
1: 143,635,772 (GRCm39) |
D458G |
probably benign |
Het |
| Sarm1 |
A |
T |
11: 78,366,133 (GRCm39) |
C649S |
probably benign |
Het |
| Septin12 |
T |
A |
16: 4,809,643 (GRCm39) |
Q223L |
probably damaging |
Het |
| Septin4 |
A |
T |
11: 87,474,262 (GRCm39) |
Q60L |
probably benign |
Het |
| Slc22a21 |
A |
T |
11: 53,870,559 (GRCm39) |
L42Q |
probably damaging |
Het |
| Slc44a1 |
GCCC |
GCCCCCCC |
4: 53,563,246 (GRCm39) |
|
probably null |
Het |
| Slc9a4 |
T |
G |
1: 40,646,901 (GRCm39) |
|
probably null |
Het |
| Sort1 |
T |
A |
3: 108,259,002 (GRCm39) |
F678Y |
probably benign |
Het |
| Spag6 |
T |
A |
2: 18,737,908 (GRCm39) |
C259* |
probably null |
Het |
| Spata31e2 |
T |
C |
1: 26,724,935 (GRCm39) |
R82G |
probably benign |
Het |
| Stard13 |
T |
C |
5: 150,968,633 (GRCm39) |
Y879C |
probably damaging |
Het |
| Stk24 |
A |
T |
14: 121,539,623 (GRCm39) |
I191N |
probably damaging |
Het |
| Tacc1 |
A |
T |
8: 25,654,509 (GRCm39) |
N271K |
probably damaging |
Het |
| Tacc2 |
T |
A |
7: 130,223,587 (GRCm39) |
S91T |
possibly damaging |
Het |
| Tacr3 |
T |
C |
3: 134,637,941 (GRCm39) |
V366A |
probably benign |
Het |
| Tasor |
A |
G |
14: 27,198,571 (GRCm39) |
N1301S |
possibly damaging |
Het |
| Tbccd1 |
A |
G |
16: 22,660,739 (GRCm39) |
S26P |
probably benign |
Het |
| Tecpr1 |
T |
A |
5: 144,145,463 (GRCm39) |
T595S |
probably benign |
Het |
| Tjp3 |
T |
A |
10: 81,113,888 (GRCm39) |
M457L |
possibly damaging |
Het |
| Tor1aip2 |
A |
G |
1: 155,941,095 (GRCm39) |
Y467C |
probably damaging |
Het |
| Ttc9b |
T |
A |
7: 27,353,774 (GRCm39) |
|
probably null |
Het |
| Tti1 |
T |
C |
2: 157,842,663 (GRCm39) |
R789G |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,662,561 (GRCm39) |
|
probably null |
Het |
| Txk |
T |
A |
5: 72,853,922 (GRCm39) |
T472S |
probably damaging |
Het |
| Ube3d |
A |
T |
9: 86,254,540 (GRCm39) |
|
probably null |
Het |
| Vav2 |
C |
A |
2: 27,189,408 (GRCm39) |
R176L |
possibly damaging |
Het |
| Vps35l |
T |
C |
7: 118,393,798 (GRCm39) |
Y516H |
probably damaging |
Het |
| Wdr27 |
T |
A |
17: 15,148,594 (GRCm39) |
D133V |
probably damaging |
Het |
| Zc3h7a |
A |
T |
16: 10,968,469 (GRCm39) |
Y503* |
probably null |
Het |
| Zdhhc13 |
T |
A |
7: 48,474,392 (GRCm39) |
L548Q |
possibly damaging |
Het |
| Zfp467 |
A |
C |
6: 48,419,595 (GRCm39) |
S38A |
probably damaging |
Het |
|
| Other mutations in Arap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00481:Arap2
|
APN |
5 |
62,793,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00642:Arap2
|
APN |
5 |
62,890,401 (GRCm39) |
nonsense |
probably null |
|
|
IGL00705:Arap2
|
APN |
5 |
62,835,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00942:Arap2
|
APN |
5 |
62,855,732 (GRCm39) |
nonsense |
probably null |
|
|
IGL01069:Arap2
|
APN |
5 |
62,807,199 (GRCm39) |
missense |
probably benign |
|
|
IGL01601:Arap2
|
APN |
5 |
62,798,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01986:Arap2
|
APN |
5 |
62,779,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02032:Arap2
|
APN |
5 |
62,828,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02262:Arap2
|
APN |
5 |
62,800,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Arap2
|
APN |
5 |
62,807,025 (GRCm39) |
splice site |
probably benign |
|
|
IGL02527:Arap2
|
APN |
5 |
62,906,650 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Arap2
|
APN |
5 |
62,906,452 (GRCm39) |
missense |
probably benign |
|
|
IGL02864:Arap2
|
APN |
5 |
62,835,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03078:Arap2
|
APN |
5 |
62,890,408 (GRCm39) |
splice site |
probably benign |
|
|
IGL03154:Arap2
|
APN |
5 |
62,800,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03213:Arap2
|
APN |
5 |
62,906,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Arap2
|
APN |
5 |
62,779,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03288:Arap2
|
APN |
5 |
62,761,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4354001:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0012:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Arap2
|
UTSW |
5 |
62,833,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0472:Arap2
|
UTSW |
5 |
62,864,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0551:Arap2
|
UTSW |
5 |
62,798,666 (GRCm39) |
splice site |
probably null |
|
|
R0607:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0617:Arap2
|
UTSW |
5 |
62,807,250 (GRCm39) |
splice site |
probably benign |
|
|
R0975:Arap2
|
UTSW |
5 |
62,888,229 (GRCm39) |
splice site |
probably benign |
|
|
R0976:Arap2
|
UTSW |
5 |
62,807,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1164:Arap2
|
UTSW |
5 |
62,840,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1268:Arap2
|
UTSW |
5 |
62,887,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1480:Arap2
|
UTSW |
5 |
62,826,472 (GRCm39) |
nonsense |
probably null |
|
|
R1502:Arap2
|
UTSW |
5 |
62,761,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1543:Arap2
|
UTSW |
5 |
62,763,498 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1962:Arap2
|
UTSW |
5 |
62,834,007 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2040:Arap2
|
UTSW |
5 |
62,906,259 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2118:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2215:Arap2
|
UTSW |
5 |
62,834,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3027:Arap2
|
UTSW |
5 |
62,827,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3053:Arap2
|
UTSW |
5 |
62,906,200 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3975:Arap2
|
UTSW |
5 |
62,906,237 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4272:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4273:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4326:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4327:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4328:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4451:Arap2
|
UTSW |
5 |
62,906,513 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4659:Arap2
|
UTSW |
5 |
62,811,469 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4665:Arap2
|
UTSW |
5 |
62,827,312 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4715:Arap2
|
UTSW |
5 |
62,906,437 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4808:Arap2
|
UTSW |
5 |
62,887,984 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4941:Arap2
|
UTSW |
5 |
62,906,821 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4983:Arap2
|
UTSW |
5 |
62,833,868 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5095:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Arap2
|
UTSW |
5 |
62,826,524 (GRCm39) |
nonsense |
probably null |
|
|
R5201:Arap2
|
UTSW |
5 |
62,840,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Arap2
|
UTSW |
5 |
62,872,089 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5359:Arap2
|
UTSW |
5 |
62,840,762 (GRCm39) |
nonsense |
probably null |
|
|
R5426:Arap2
|
UTSW |
5 |
62,800,159 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5503:Arap2
|
UTSW |
5 |
62,787,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Arap2
|
UTSW |
5 |
62,772,410 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5764:Arap2
|
UTSW |
5 |
62,800,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Arap2
|
UTSW |
5 |
62,834,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5846:Arap2
|
UTSW |
5 |
62,807,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Arap2
|
UTSW |
5 |
62,828,297 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6173:Arap2
|
UTSW |
5 |
62,906,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Arap2
|
UTSW |
5 |
62,872,074 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6249:Arap2
|
UTSW |
5 |
62,803,536 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6386:Arap2
|
UTSW |
5 |
62,761,865 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6424:Arap2
|
UTSW |
5 |
62,840,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6744:Arap2
|
UTSW |
5 |
62,906,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6766:Arap2
|
UTSW |
5 |
62,834,443 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6990:Arap2
|
UTSW |
5 |
62,833,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7067:Arap2
|
UTSW |
5 |
62,811,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7098:Arap2
|
UTSW |
5 |
62,833,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7107:Arap2
|
UTSW |
5 |
62,763,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7156:Arap2
|
UTSW |
5 |
62,761,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Arap2
|
UTSW |
5 |
62,761,621 (GRCm39) |
missense |
probably benign |
|
|
R7187:Arap2
|
UTSW |
5 |
62,826,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7197:Arap2
|
UTSW |
5 |
62,798,729 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7214:Arap2
|
UTSW |
5 |
62,906,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7317:Arap2
|
UTSW |
5 |
62,807,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7392:Arap2
|
UTSW |
5 |
62,855,728 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7438:Arap2
|
UTSW |
5 |
62,906,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7452:Arap2
|
UTSW |
5 |
62,833,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7495:Arap2
|
UTSW |
5 |
62,833,893 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7796:Arap2
|
UTSW |
5 |
62,888,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Arap2
|
UTSW |
5 |
62,888,048 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8116:Arap2
|
UTSW |
5 |
62,887,954 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Arap2
|
UTSW |
5 |
62,779,324 (GRCm39) |
splice site |
probably null |
|
|
R8277:Arap2
|
UTSW |
5 |
62,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Arap2
|
UTSW |
5 |
62,761,669 (GRCm39) |
nonsense |
probably null |
|
|
R8398:Arap2
|
UTSW |
5 |
62,906,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Arap2
|
UTSW |
5 |
62,888,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Arap2
|
UTSW |
5 |
62,855,668 (GRCm39) |
nonsense |
probably null |
|
|
R9102:Arap2
|
UTSW |
5 |
62,906,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9121:Arap2
|
UTSW |
5 |
62,906,326 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9174:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Arap2
|
UTSW |
5 |
62,828,421 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9281:Arap2
|
UTSW |
5 |
62,906,848 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9399:Arap2
|
UTSW |
5 |
62,763,455 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9450:Arap2
|
UTSW |
5 |
62,855,762 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9467:Arap2
|
UTSW |
5 |
62,887,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9567:Arap2
|
UTSW |
5 |
62,761,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9577:Arap2
|
UTSW |
5 |
62,769,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Arap2
|
UTSW |
5 |
62,906,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9688:Arap2
|
UTSW |
5 |
62,872,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CACTTTCGTCAGAGTCGTCAC -3'
(R):5'- ACACACATAACATGCTTTGAGC -3'
Sequencing Primer
(F):5'- GAGTCGTCACATCTTCACATTCTGAG -3'
(R):5'- ACATGCTTTGAGCTATATTCCCAG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation