Incidental Mutation 'R2058:Ano1'
| ID |
228372 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ano1
|
| Ensembl Gene |
ENSMUSG00000031075 |
| Gene Name |
anoctamin 1, calcium activated chloride channel |
| Synonyms |
Tmem16a |
| MMRRC Submission |
040063-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R2058 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
144588549-144751974 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 144648052 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 334
(V334A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113899
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033393]
[ENSMUST00000118556]
[ENSMUST00000121758]
[ENSMUST00000155175]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000033393
AA Change: V276A
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000033393
Gene: ENSMUSG00000031075
AA Change: V276A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
129 |
147 |
N/A |
INTRINSIC |
|
Pfam:Anoctamin
|
320 |
898 |
1.3e-149 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000118556
AA Change: V334A
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000113899
Gene: ENSMUSG00000031075
AA Change: V334A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Anoct_dimer
|
112 |
375 |
5.5e-83 |
PFAM |
|
Pfam:Anoctamin
|
378 |
955 |
6.7e-140 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000121758
AA Change: V333A
PolyPhen 2
Score 0.891 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000112616
Gene: ENSMUSG00000031075
AA Change: V333A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Anoct_dimer
|
54 |
317 |
7.1e-83 |
PFAM |
|
Pfam:Anoctamin
|
320 |
901 |
2.2e-139 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000152531
AA Change: V163A
|
| SMART Domains |
Protein: ENSMUSP00000119653
Gene: ENSMUSG00000031075
AA Change: V163A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Anoct_dimer
|
2 |
205 |
4.4e-64 |
PFAM |
|
Pfam:Anoctamin
|
208 |
335 |
3e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155175
|
| SMART Domains |
Protein: ENSMUSP00000120306
Gene: ENSMUSG00000031075
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
153 |
171 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208985
|
| Meta Mutation Damage Score |
0.3632 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 94.6%
|
| Validation Efficiency |
99% (94/95) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knockout allele exhibit postnatal death associated with aerophagia, slow postnatal weight gain, cyanosis, and abnormal tracheal morphology. Mice homozygous for a different knock-out allele exhibit proteinuria and intracellular endosomal vesicles in PTE cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam18 |
A |
T |
8: 24,672,066 (GRCm38) |
|
probably benign |
Het |
| Adgrf5 |
A |
G |
17: 43,428,586 (GRCm38) |
Y72C |
possibly damaging |
Het |
| Alas1 |
T |
C |
9: 106,241,290 (GRCm38) |
E211G |
probably damaging |
Het |
| Alkbh1 |
C |
T |
12: 87,443,750 (GRCm38) |
|
probably benign |
Het |
| Arhgap18 |
C |
T |
10: 26,854,908 (GRCm38) |
T122I |
probably benign |
Het |
| Arhgef4 |
A |
G |
1: 34,722,377 (GRCm38) |
K238R |
unknown |
Het |
| Atf6b |
A |
T |
17: 34,648,575 (GRCm38) |
|
probably null |
Het |
| Atp2a1 |
G |
A |
7: 126,447,672 (GRCm38) |
A847V |
possibly damaging |
Het |
| Baz1b |
T |
A |
5: 135,217,225 (GRCm38) |
N509K |
probably benign |
Het |
| BC051076 |
A |
T |
5: 87,963,985 (GRCm38) |
|
noncoding transcript |
Het |
| Cage1 |
A |
G |
13: 38,023,380 (GRCm38) |
V163A |
probably benign |
Het |
| Canx |
T |
C |
11: 50,304,425 (GRCm38) |
N272S |
probably damaging |
Het |
| Cd302 |
T |
A |
2: 60,252,423 (GRCm38) |
I186F |
possibly damaging |
Het |
| Cd84 |
A |
G |
1: 171,872,750 (GRCm38) |
T145A |
possibly damaging |
Het |
| Cep112 |
T |
A |
11: 108,519,261 (GRCm38) |
|
probably null |
Het |
| Cmtm4 |
A |
C |
8: 104,355,288 (GRCm38) |
F156V |
probably damaging |
Het |
| Col4a1 |
T |
A |
8: 11,210,792 (GRCm38) |
D1330V |
probably damaging |
Het |
| Ctsa |
T |
G |
2: 164,834,902 (GRCm38) |
M136R |
probably null |
Het |
| Cyp2d10 |
T |
A |
15: 82,403,814 (GRCm38) |
I363F |
probably damaging |
Het |
| Dmbt1 |
G |
A |
7: 131,106,170 (GRCm38) |
A1381T |
possibly damaging |
Het |
| Dmwd |
T |
A |
7: 19,080,727 (GRCm38) |
L434Q |
probably damaging |
Het |
| Fat4 |
T |
A |
3: 38,891,170 (GRCm38) |
M1404K |
possibly damaging |
Het |
| Gcc2 |
T |
A |
10: 58,285,957 (GRCm38) |
S1102T |
probably benign |
Het |
| Gcm2 |
T |
C |
13: 41,109,954 (GRCm38) |
M1V |
probably null |
Het |
| Gna14 |
G |
C |
19: 16,608,141 (GRCm38) |
|
probably benign |
Het |
| Gsk3b |
T |
A |
16: 38,187,909 (GRCm38) |
D192E |
probably benign |
Het |
| Gulo |
A |
G |
14: 65,991,159 (GRCm38) |
V270A |
possibly damaging |
Het |
| Hps5 |
T |
A |
7: 46,768,051 (GRCm38) |
D904V |
probably damaging |
Het |
| Il7 |
A |
T |
3: 7,573,915 (GRCm38) |
N130K |
probably damaging |
Het |
| Jak3 |
A |
T |
8: 71,685,383 (GRCm38) |
|
probably null |
Het |
| Klhl6 |
T |
G |
16: 19,982,931 (GRCm38) |
T25P |
probably benign |
Het |
| Kremen2 |
T |
C |
17: 23,742,717 (GRCm38) |
E272G |
possibly damaging |
Het |
| Map3k21 |
A |
G |
8: 125,938,722 (GRCm38) |
K550R |
probably benign |
Het |
| Mphosph10 |
T |
A |
7: 64,376,751 (GRCm38) |
L650F |
probably damaging |
Het |
| Mrpl48 |
T |
C |
7: 100,549,333 (GRCm38) |
E204G |
probably damaging |
Het |
| Msh5 |
A |
C |
17: 35,029,756 (GRCm38) |
V738G |
probably damaging |
Het |
| Mybph |
G |
A |
1: 134,200,119 (GRCm38) |
C473Y |
probably damaging |
Het |
| Nid1 |
A |
C |
13: 13,500,473 (GRCm38) |
H926P |
probably benign |
Het |
| Nlrp9a |
T |
A |
7: 26,557,362 (GRCm38) |
I46K |
possibly damaging |
Het |
| Notch3 |
T |
C |
17: 32,143,644 (GRCm38) |
T1336A |
probably benign |
Het |
| Nsun4 |
T |
C |
4: 116,053,680 (GRCm38) |
|
probably null |
Het |
| Olfr1023 |
A |
T |
2: 85,886,952 (GRCm38) |
T51S |
possibly damaging |
Het |
| Olfr390 |
A |
G |
11: 73,787,274 (GRCm38) |
N112S |
probably benign |
Het |
| Osgin1 |
A |
G |
8: 119,445,673 (GRCm38) |
D402G |
possibly damaging |
Het |
| Patl1 |
A |
G |
19: 11,932,147 (GRCm38) |
E479G |
possibly damaging |
Het |
| Pbsn |
T |
C |
X: 77,847,976 (GRCm38) |
K72E |
probably damaging |
Het |
| Pcdhb13 |
A |
G |
18: 37,444,567 (GRCm38) |
Q666R |
possibly damaging |
Het |
| Pi4k2b |
G |
A |
5: 52,750,680 (GRCm38) |
V131I |
probably benign |
Het |
| Pkn2 |
G |
A |
3: 142,853,471 (GRCm38) |
H98Y |
possibly damaging |
Het |
| Pms1 |
A |
G |
1: 53,275,168 (GRCm38) |
Y73H |
probably benign |
Het |
| Ppt2 |
A |
T |
17: 34,622,844 (GRCm38) |
|
probably benign |
Het |
| Prkdc |
A |
G |
16: 15,727,605 (GRCm38) |
T1862A |
probably benign |
Het |
| Prl6a1 |
T |
C |
13: 27,319,098 (GRCm38) |
Y231H |
probably benign |
Het |
| Ranbp3l |
T |
A |
15: 9,000,817 (GRCm38) |
V41D |
probably damaging |
Het |
| Rhobtb2 |
T |
C |
14: 69,794,039 (GRCm38) |
T546A |
possibly damaging |
Het |
| Ripk4 |
A |
T |
16: 97,744,142 (GRCm38) |
L372* |
probably null |
Het |
| Rnf126 |
A |
G |
10: 79,759,137 (GRCm38) |
|
probably benign |
Het |
| S100pbp |
A |
G |
4: 129,182,100 (GRCm38) |
V144A |
probably benign |
Het |
| Saal1 |
T |
C |
7: 46,699,456 (GRCm38) |
Q317R |
probably damaging |
Het |
| Sap25 |
G |
A |
5: 137,642,772 (GRCm38) |
G277R |
probably damaging |
Het |
| Senp2 |
C |
T |
16: 22,014,199 (GRCm38) |
T79I |
probably damaging |
Het |
| Serpinb9c |
A |
T |
13: 33,156,871 (GRCm38) |
C81* |
probably null |
Het |
| Set |
A |
G |
2: 30,069,036 (GRCm38) |
K70E |
possibly damaging |
Het |
| Setd3 |
A |
G |
12: 108,107,341 (GRCm38) |
I559T |
probably benign |
Het |
| Sik1 |
A |
G |
17: 31,848,797 (GRCm38) |
S435P |
probably benign |
Het |
| Skint3 |
A |
T |
4: 112,255,783 (GRCm38) |
K197* |
probably null |
Het |
| Skint5 |
T |
A |
4: 113,870,700 (GRCm38) |
I402F |
possibly damaging |
Het |
| Slc18a1 |
G |
A |
8: 69,043,961 (GRCm38) |
T350M |
probably damaging |
Het |
| Slc19a3 |
A |
T |
1: 83,014,791 (GRCm38) |
I403K |
probably damaging |
Het |
| Slc1a7 |
C |
T |
4: 108,004,439 (GRCm38) |
T225I |
probably benign |
Het |
| Slc38a4 |
T |
C |
15: 97,008,725 (GRCm38) |
I336V |
probably benign |
Het |
| Smarcc1 |
A |
G |
9: 110,118,343 (GRCm38) |
|
probably benign |
Het |
| St8sia5 |
A |
T |
18: 77,254,763 (GRCm38) |
I390F |
probably damaging |
Het |
| Strc |
A |
T |
2: 121,378,887 (GRCm38) |
W290R |
probably damaging |
Het |
| Svep1 |
T |
C |
4: 58,084,554 (GRCm38) |
D1858G |
possibly damaging |
Het |
| Sympk |
G |
A |
7: 19,043,529 (GRCm38) |
R568Q |
probably damaging |
Het |
| Tex44 |
A |
C |
1: 86,427,006 (GRCm38) |
K212N |
probably damaging |
Het |
| Tgm4 |
T |
C |
9: 123,061,770 (GRCm38) |
I54T |
probably damaging |
Het |
| Thrap3 |
C |
T |
4: 126,180,174 (GRCm38) |
V260I |
probably damaging |
Het |
| Thsd7a |
A |
T |
6: 12,318,106 (GRCm38) |
|
probably benign |
Het |
| Trim12c |
A |
G |
7: 104,348,191 (GRCm38) |
F53L |
possibly damaging |
Het |
| Ttc6 |
T |
A |
12: 57,737,693 (GRCm38) |
D1849E |
probably benign |
Het |
| Ubap2l |
A |
T |
3: 90,031,376 (GRCm38) |
|
probably benign |
Het |
| Umodl1 |
G |
A |
17: 31,008,766 (GRCm38) |
|
probably null |
Het |
| Usp17la |
A |
C |
7: 104,861,171 (GRCm38) |
T328P |
probably damaging |
Het |
| Vmn2r113 |
T |
A |
17: 22,958,249 (GRCm38) |
L669* |
probably null |
Het |
| Vps13b |
T |
A |
15: 35,841,447 (GRCm38) |
V2541E |
probably damaging |
Het |
| Wnt3 |
T |
C |
11: 103,812,285 (GRCm38) |
I198T |
probably damaging |
Het |
| Zfp316 |
T |
C |
5: 143,263,406 (GRCm38) |
E158G |
unknown |
Het |
| Zfp362 |
T |
G |
4: 128,786,987 (GRCm38) |
I182L |
possibly damaging |
Het |
| Zfp804a |
A |
G |
2: 82,257,366 (GRCm38) |
D513G |
probably benign |
Het |
| Zfp879 |
C |
T |
11: 50,832,601 (GRCm38) |
E543K |
probably benign |
Het |
| Zfp97 |
T |
A |
17: 17,144,756 (GRCm38) |
N172K |
possibly damaging |
Het |
| Zmym6 |
A |
T |
4: 127,088,415 (GRCm38) |
K82* |
probably null |
Het |
|
| Other mutations in Ano1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00595:Ano1
|
APN |
7 |
144,638,513 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00754:Ano1
|
APN |
7 |
144,597,231 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL00780:Ano1
|
APN |
7 |
144,655,630 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL00918:Ano1
|
APN |
7 |
144,644,752 (GRCm38) |
splice site |
probably benign |
|
|
IGL01112:Ano1
|
APN |
7 |
144,637,145 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
IGL01285:Ano1
|
APN |
7 |
144,644,742 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01285:Ano1
|
APN |
7 |
144,595,538 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01308:Ano1
|
APN |
7 |
144,595,498 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01407:Ano1
|
APN |
7 |
144,637,111 (GRCm38) |
missense |
probably benign |
0.22 |
|
IGL01672:Ano1
|
APN |
7 |
144,655,675 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01920:Ano1
|
APN |
7 |
144,611,454 (GRCm38) |
splice site |
probably benign |
|
|
IGL01926:Ano1
|
APN |
7 |
144,610,875 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL02164:Ano1
|
APN |
7 |
144,637,181 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL02190:Ano1
|
APN |
7 |
144,618,883 (GRCm38) |
missense |
probably benign |
0.41 |
|
IGL02214:Ano1
|
APN |
7 |
144,655,708 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
IGL02299:Ano1
|
APN |
7 |
144,590,075 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
IGL02567:Ano1
|
APN |
7 |
144,611,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03131:Ano1
|
APN |
7 |
144,603,585 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL03291:Ano1
|
APN |
7 |
144,621,675 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03299:Ano1
|
APN |
7 |
144,654,256 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03394:Ano1
|
APN |
7 |
144,595,439 (GRCm38) |
splice site |
probably null |
|
|
PIT4434001:Ano1
|
UTSW |
7 |
144,610,895 (GRCm38) |
missense |
probably benign |
0.28 |
|
R0502:Ano1
|
UTSW |
7 |
144,597,215 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0595:Ano1
|
UTSW |
7 |
144,590,153 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R0732:Ano1
|
UTSW |
7 |
144,619,488 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R0970:Ano1
|
UTSW |
7 |
144,595,571 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0988:Ano1
|
UTSW |
7 |
144,633,653 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1074:Ano1
|
UTSW |
7 |
144,611,680 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1301:Ano1
|
UTSW |
7 |
144,633,689 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R1528:Ano1
|
UTSW |
7 |
144,595,566 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2018:Ano1
|
UTSW |
7 |
144,654,250 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2056:Ano1
|
UTSW |
7 |
144,648,052 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2057:Ano1
|
UTSW |
7 |
144,648,052 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2059:Ano1
|
UTSW |
7 |
144,611,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2860:Ano1
|
UTSW |
7 |
144,590,012 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2861:Ano1
|
UTSW |
7 |
144,590,012 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3770:Ano1
|
UTSW |
7 |
144,595,569 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3970:Ano1
|
UTSW |
7 |
144,607,963 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4179:Ano1
|
UTSW |
7 |
144,650,505 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4489:Ano1
|
UTSW |
7 |
144,611,742 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4678:Ano1
|
UTSW |
7 |
144,669,552 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4915:Ano1
|
UTSW |
7 |
144,611,375 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R5114:Ano1
|
UTSW |
7 |
144,657,083 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R5362:Ano1
|
UTSW |
7 |
144,648,600 (GRCm38) |
unclassified |
probably benign |
|
|
R5364:Ano1
|
UTSW |
7 |
144,637,204 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5366:Ano1
|
UTSW |
7 |
144,654,209 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5387:Ano1
|
UTSW |
7 |
144,648,619 (GRCm38) |
missense |
probably benign |
|
|
R5762:Ano1
|
UTSW |
7 |
144,648,037 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5857:Ano1
|
UTSW |
7 |
144,637,103 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6091:Ano1
|
UTSW |
7 |
144,669,434 (GRCm38) |
missense |
probably benign |
0.12 |
|
R6093:Ano1
|
UTSW |
7 |
144,611,377 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R6177:Ano1
|
UTSW |
7 |
144,678,741 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R6246:Ano1
|
UTSW |
7 |
144,633,725 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R6274:Ano1
|
UTSW |
7 |
144,618,863 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6323:Ano1
|
UTSW |
7 |
144,611,686 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6574:Ano1
|
UTSW |
7 |
144,607,916 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6782:Ano1
|
UTSW |
7 |
144,621,687 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6880:Ano1
|
UTSW |
7 |
144,644,742 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6909:Ano1
|
UTSW |
7 |
144,655,731 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7066:Ano1
|
UTSW |
7 |
144,637,086 (GRCm38) |
missense |
probably benign |
0.35 |
|
R7073:Ano1
|
UTSW |
7 |
144,638,552 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7146:Ano1
|
UTSW |
7 |
144,655,656 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7420:Ano1
|
UTSW |
7 |
144,655,641 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7874:Ano1
|
UTSW |
7 |
144,621,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8468:Ano1
|
UTSW |
7 |
144,655,620 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8867:Ano1
|
UTSW |
7 |
144,669,660 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R8923:Ano1
|
UTSW |
7 |
144,650,551 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9215:Ano1
|
UTSW |
7 |
144,595,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9281:Ano1
|
UTSW |
7 |
144,595,581 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9572:Ano1
|
UTSW |
7 |
144,650,556 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R9668:Ano1
|
UTSW |
7 |
144,610,842 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9681:Ano1
|
UTSW |
7 |
144,590,156 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R9756:Ano1
|
UTSW |
7 |
144,608,929 (GRCm38) |
missense |
probably benign |
0.45 |
|
R9780:Ano1
|
UTSW |
7 |
144,655,621 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9792:Ano1
|
UTSW |
7 |
144,621,697 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9793:Ano1
|
UTSW |
7 |
144,621,697 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9795:Ano1
|
UTSW |
7 |
144,621,697 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCTGCCAGCCAAAACTGCC -3'
(R):5'- TGCCTTCTACCCAGGGAAGAAC -3'
Sequencing Primer
(F):5'- AAAACTGCCCTGTGTGTGAC -3'
(R):5'- ACCCCAAGATGGTGACTGG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation